People with HIV who are undiagnosed and those with detectable viral load less likely to use condoms, South African study findsMichael Carter | 6 years ago People with HIV who don't use condoms consistently are more likely to be unaware they are HIV-posit......MORE |
HIV-positive transgender men in US have significant unmet medical and social needsMichael Carter | 6 years ago HIV-positive transgender men in the United States have significant unmet social and healthcare need......MORE |
HIV drug resistance now high enough to trigger a change in first-line treatment in eastern and southern AfricaKeith Alcorn | 6 years ago HIV drug resistance is increasing rapidly in southern and eastern Africa and Latin America and, as......MORE |
ART reduces prevalence of cervical infection with high-risk HPV, pre-cancerous cell changes and cervical cancerMichael Carter | 6 years ago Antiretroviral therapy (ART) is associated with a lower prevalence of high-risk cervical HPV infect......MORE |
ART reduces prevalence of cervical infection with high-risk HPV, pre-cancerous cell changes and cervical cancerMichael Carter | 6 years ago Antiretroviral therapy (ART) is associated with a lower prevalence of high-risk cervical human papi......MORE |
Many Americans still get their HIV diagnosis years after infectionLiz Highleyman | 6 years ago Many people with HIV in the United States are still being diagnosed with HIV late, and therefore no......MORE |
HIV testing rate among children and adolescents boosted after caregivers receive a cash incentiveMichael Carter | 6 years ago Children and adolescents are more likely to be tested for HIV if their parents or caregivers are of......MORE |
HIV testing rate among children and adolescents boosted after care-givers receive a cash incentiveMichael Carter | 6 years ago Children and adolescents are more likely to be tested for HIV if their parents or caregivers are of......MORE |
More work and lower drug prices are needed to eliminate hepatitis C worldwideLiz Highleyman | 6 years ago Eliminating hepatitis C virus (HCV) as a global public health concern is feasible, but to do this m......MORE |
Sofosbuvir/ledipasvir for 8 weeks cures acute HCV in people with HIVLiz Highleyman | 6 years ago An 8-week course of sofosbuvir/ledipasvir (Harvoni) led to a sustained response in all people with ......MORE |
HIV-positive children in resource-limited settings can achieve good virological outcomes without routine viral load or CD4 cell count monitoringMichael Carter | 6 years ago HIV-positive children can achieve good virological outcomes without routine monitoring of CD4 cell ......MORE |
Undetectable viral load at time of immunisation enhances yellow fever vaccine protection for people with HIVMichael Carter | 6 years ago Viral suppression at the time of immunisation is the most important determinant of long-term respon......MORE |
To better target HIV prevention, identify people whose social contacts have high viral loadsRoger Pebody | 6 years ago Rather than relying on assessment of an individual’s sexual behaviour or of ‘community viral lo......MORE |
Despite reassuring data, we can’t yet say U=U for breastfeedingRoger Pebody | 6 years ago While effective HIV treatment greatly reduces the risk of onward transmission during breastfeeding,......MORE |
Risk of chronic kidney disease and cardiovascular disease in people with HIV should be assessed togetherMichael Carter | 6 years ago People with HIV should have their risk of cardiovascular disease (CVD) and chronic kidney disease (......MORE |
Schistosomiasis increases risk of infection with HIV, especially for women and is also associated with a higher HIV viral loadMichael Carter | 6 years ago Infection with schistosome parasitic worms has an important role in HIV transmission, especially fo......MORE |
Gay men’s stories of monogamy and non-monogamy: change, flexibility and tensionsRoger Pebody | 6 years ago Although some gay men idealise monogamy, particularly in the early stages of a relationship, couple......MORE |
European Cure Review concentrates on HIV therapeutic vaccinesGus Cairns | 6 years ago A cure for HIV would almost inevitably have to involve a vaccine to improve the body’s natural ab......MORE |
Who is taking an HIV test in England and where?Roger Pebody | 6 years ago The range of settings in which people test for HIV has expanded significantly in recent years in En......MORE |
HIV incidence is falling in English gay men, say Public Health EnglandRoger Pebody | 6 years ago While several recent reports have shown that new HIV diagnoses have been falling in UK gay men, wha......MORE |
Screen all HIV-positive MSM for pre-cancerous anal cell changes, say Dutch investigatorsMichael Carter | 6 years ago Younger age and shorter duration of viral suppression are risk factors for the development of high-......MORE |
Nivolumab improves outcomes in liver cancer studyLiz Highleyman | 6 years ago Nivolumab (Opdivo), a PD-1 checkpoint inhibitor that helps the immune system fight cancer, was asso......MORE |
No change in cognitive function or brain structure in people taking effective HIV treatment for 2 yearsKeith Alcorn | 6 years ago People with HIV taking antiretroviral treatment who had undetectable viral load did not suffer any ......MORE |
Up to a quarter of HIV-negative gay men attending three English clinics used PrEP in the last yearGus Cairns | 6 years ago A prospective cohort study of gay men attending three clinics in southern England – 56 Dean St an......MORE |
Healthcare workers living with HIV have different motivations for disclosing or concealing their HIV statusRoger Pebody | 6 years ago Nurses and other healthcare workers who are living with HIV have mixed reactions when they mention ......MORE |
HIV diagnoses in English gay men have been falling since 2014Gus Cairns | 6 years ago A new analysis by Public Health England of testing rates and HIV diagnoses from all of England’s ......MORE |
High HIV incidence from non-primary partners and low PEP and PREP use seen in PARTNER studyGus Cairns | 6 years ago HIV incidence among the HIV-negative gay men in the PARTNER 1 and 2 studies, due to sex with partne......MORE |
European AIDS Clinical Society strengthens HPV vaccination adviceKeith Alcorn | 6 years ago The European AIDS Clinical Society (EACS) has recommended HPV (human papillomavirus) vaccination fo......MORE |
People with HIV more likely to adhere to their antiretroviral therapy than treatment for other chronic health problemsMichael Carter | 6 years ago Ageing HIV-positive people have significantly higher levels of adherence to their antiretroviral th......MORE |
Starting ART immediately after HIV diagnosis cuts mortality risk by two-thirds for people with high CD4 cell countsMichael Carter | 6 years ago People with a high CD4 cell count who start antiretroviral therapy (ART) immediately after diagnosi......MORE |
Starting ART immediately after HIV diagnosis cuts mortality risk by two-thirds for patients with high CD4 cell countsMichael Carter | 6 years ago Patients with a high CD4 cell count who start antiretroviral therapy (ART) immediately after diagno......MORE |
Swiss study examines which years gay men decided to stop consistent condom useGus Cairns | 6 years ago An innovative study presented at the 16th European AIDS conference in Milan two weeks ago used a ma......MORE |
Survey of dating app users finds that PrEP usage has not increased in Europe in the last yearGus Cairns | 6 years ago A study of men who have sex with men (MSM) conducted by the European Centre for Disease Control and......MORE |
Global progress towards hepatitis C elimination still blocked by cost of treatment, lack of diagnosisKeith Alcorn | 6 years ago Nine countries — Australia, Brazil, Egypt, Georgia, Germany, Iceland, Japan, the Netherlands and ......MORE |
UK elimination of hepatitis C in jeopardy unless more patients foundKeith Alcorn | 6 years ago Just one in three people with hepatitis C in the United Kingdom has been diagnosed according to the......MORE |
Hepatitis C test-and-treat programme reduces HCV by two-thirds among men who have sex with Men in Swiss HIV CohortKeith Alcorn | 6 years ago A systematic policy of test-and-treat cured 99% of men who have sex with men with hepatitis C in th......MORE |
Curing hepatitis C with DAAs linked to 71% reduction in liver cancerLiz Highleyman | 6 years ago People who achieved a sustained response to hepatitis C treatment lowered their risk of hepatocellu......MORE |
High rate of hepatitis C reinfection in German men who have sex with menKeith Alcorn | 6 years ago Around one in seven gay and bisexual men cured of hepatitis C at major treatment centres in German......MORE |
Symtuza as effective as multi-pill combination in previously untreated people with HIVKeith Alcorn | 6 years ago The single-pill combination of darunavir, cobicistat, tenofovir alafenamide and emtricitabine (Symt......MORE |
Fostemsavir controls viral load in half of people with highly drug-resistant HIVKeith Alcorn | 6 years ago Fostemsavir, a new experimental attachment inhibitor, suppressed viral load in over half of partici......MORE |
Hepatitis C halved in Spanish people living with HIV in one year due to treatmentKeith Alcorn | 6 years ago Spain is making dramatic progress towards eliminating hepatitis C in people living with HIV because......MORE |
People with HIV still expect a lower quality of life than their negative peers, European survey findsGus Cairns | 6 years ago A study commissioned by the drug company Gilead Sciences and conducted in five European countries h......MORE |
New EACS treatment guidelinesKeith Alcorn | 6 years ago Everyone with HIV and HCV co-infection should receive direct-acting antiviral treatment for hepatit......MORE |
How a London clinic reduced new HIV infections by 90% and why more European cities can do the sameKeith Alcorn | 6 years ago Scaling up HIV testing to reduce undiagnosed HIV infection requires a fundamental re-ordering of HI......MORE |
ABX464 reduces HIV reservoir but doesn’t delay viral reboundKeith Alcorn | 6 years ago ABX464, a new drug that stimulates the clearance of HIV from infected cells, reduces the reservoir ......MORE |
Boosted protease inhibitor and lamivudine provides effective maintenance treatmentKeith Alcorn | 6 years ago HIV maintenance treatment with two drugs, a boosted protease inhibitor and lamivudine, is just as e......MORE |
Daily aspirin therapy linked to lower liver cancer riskLiz Highleyman | 6 years ago People with hepatitis B virus (HBV) who took an aspirin a day – often recommended to help prevent......MORE |
Hepatitis C testing linked to reduced opioid use among people who inject drugsLiz Highleyman | 6 years ago Getting tested for hepatitis C virus (HCV) was associated with reduced drug use, especially among t......MORE |
Maviret cures most people with HCV genotype 3 and those with cirrhosisLiz Highleyman | 6 years ago Glecaprevir and pibrentasvir, the two drugs in the recently approved Maviret co-formulation, demons......MORE |
HCV infection is rising among HIV-positive gay men in San DiegoLiz Highleyman | 6 years ago Hepatitis C incidence is increasing among gay and bisexual men living with HIV in San Diego, accord......MORE |
Hepatitis C cure leads to improved quality of lifeLiz Highleyman | 6 years ago People who were cured of hepatitis C with direct-acting antivirals (DAAs) had sustained improvement......MORE |
A year of generic PrEP could recoup its own cost within five years if effectiveness is high, Public Health England model findsGus Cairns | 6 years ago A cost-effectiveness model developed by Public Health England finds that just one year’s worth of......MORE |
PrEP would save the NHS money, in numerous scenariosRoger Pebody | 6 years ago A PrEP programme for men who have sex with men in the UK would not only be cost-effective, but actu......MORE |
Restrictions on free DAA access in many European countries contrary to guidelines and undermine HCV elimination targets, say researchersMichael Carter | 6 years ago The restrictions which many European countries impose on free/reimbursed access to hepatitis C viru......MORE |
MSM in London diagnosed with early syphilis are a priority group for PrEP, suggests UK studyMichael Carter | 6 years ago Gay and other men who have sex with men (MSM) recently diagnosed with early syphilis are a priority......MORE |
Symtuza protease inhibitor regimen maintains viral suppression for a yearLiz Highleyman | 6 years ago People who switched from a multi-pill antiretroviral regimen to the first one-pill, once-daily regi......MORE |
Long-acting monoclonal antibody effective against multidrug-resistant HIVLiz Highleyman | 6 years ago Ibalizumab, a long-acting monoclonal antibody that prevents HIV from entering cells, maintained vir......MORE |
Rapid fibrosis progression in large proportion of HIV-positive gay men after acute HCVMichael Carter | 6 years ago Over a third of HIV-positive gay men develop significant liver fibrosis after an episode of acute h......MORE |
Impact of side-effects on retention in HIV care is underestimated, African study suggestsKeith Alcorn | 6 years ago The impact of drug side-effects on retention in HIV care is probably being underestimated, accordin......MORE |
Impact of side effects on retention in HIV care is underestimated, African study suggestsKeith Alcorn | 6 years ago The impact of drug side effects on retention in HIV care is probably being underestimated, accordin......MORE |
Many gay/bisexual men currently taking PrEP would switch to injectable forms of the therapy should it become availableMichael Carter | 6 years ago Approximately a third of gay and bisexual men who are currently taking oral (tenofovir/emtricitabin......MORE |
People with HIV/HCV co-infection have an increased risk of cardiovascular disease compared to people with HIV aloneMichael Carter | 6 years ago People with HIV/hepatitis C virus (HCV) co-infection are between a quarter and a third more likely ......MORE |
HIV diagnoses in the UK fell in gay men last year for the first time since the mid-1990s, Public Health England confirmsGus Cairns | 6 years ago The 2016 HIV surveillance figures released by Public Health England (PHE) today reveal that what ha......MORE |
Virally-suppressed people have “effectively no risk” of transmitting HIV, says US CDC: but how many are suppressed?Gus Cairns | 6 years ago The US Centers for Disease Control and Prevention (CDC) used 27 September, National Gay Men’s HIV......MORE |
Virally suppressed people have “effectively no risk” of transmitting HIV, says US CDC: but how many are suppressed?Gus Cairns | 6 years ago The US Centers for Disease Control and Prevention (CDC) used 27 September, National Gay Men’s HIV......MORE |
Drinking three or more cups of coffee a day halves the risk of dying for people with HIV/HCV co-infectionMichael Carter | 6 years ago Drinking three or more cups of coffee a day halves the risk of death from any cause for people with......MORE |
Amsterdam PrEP failure patient had unusual course of HIV infectionGus Cairns | 6 years ago At last February’s Conference on Retroviruses and Opportunistic Infections (CROI), Dutch clinicia......MORE |
Depression highly prevalent among people living with HIV in sub-Saharan AfricaMichael Carter | 6 years ago Depression is very common among people living with HIV (PLHIV) in sub-Saharan Africa (SSA), accordi......MORE |
US FDA approves nivolumab immunotherapy for liver cancerLiz Highleyman | 6 years ago The US Food and Drug Administration (FDA) last week granted accelerated approval for nivolumab (Opd......MORE |
HIV diagnoses on the rise among over-50s in EuropeKeith Alcorn | 6 years ago Just over one in six people diagnosed with HIV in Europe between 2004 and 2015 was over 50 years of......MORE |
People living with HIV in the UK not receiving appropriate monitoring of heart disease riskMichael Carter | 6 years ago The majority of HIV-positive people in the UK are not receiving recommended monitoring of cardiovas......MORE |
Australian clinic records show significant reduction in duration of infectiousness in HIV-positive gay men from 2007-2016Michael Carter | 6 years ago The period during which HIV-positive men who have sex with men (MSM) are potentially infectious fel......MORE |
Marathon training is safe for people with HIVMichael Carter | 6 years ago Marathon run training is safe for people with HIV, investigators from Germany report in BMC Infecti......MORE |
Does drug injection equipment other than syringes transmit hepatitis C?Liz Highleyman | 6 years ago Sharing drug preparation paraphernalia may not significantly contribute to hepatitis C virus (HCV) ......MORE |
Smokers with HIV doing well on treatment now at greater risk of lung cancer than AIDSKeith Alcorn | 6 years ago People living with HIV on antiretroviral treatment with fully suppressed viral load who smoke are m......MORE |
San Francisco annual report shows continued drop in new HIV infectionsLiz Highleyman | 6 years ago The San Francisco Department of Public Health has released its HIV Epidemiology Annual Report for 2......MORE |
High prices of DAAs mean there's been little progress towards achieving WHO target of eliminating HCV by 2030Michael Carter | 6 years ago Only a handful of countries are on course to achieve the World Health Organization (WHO) target of......MORE |
Study documents changing opinion among Italian doctors about PrEPGus Cairns | 6 years ago A survey of Italian infectious disease physicians working with HIV, conducted in 2015 but only publ......MORE |
New guidelines recommend that women avoid tenofovir & emtricitabine during pregnancyKeith Alcorn | 6 years ago Women should be offered the choice to avoid treatment with tenofovir and emtricitabine during pregn......MORE |
New US PrEP cost-effectiveness model finds drug prices will need to drop substantially if HIV risk rises, or if adherence is only moderateGus Cairns | 6 years ago A new US model of the cost-effectiveness of pre-exposure prophylaxis (PrEP) for men who have sex wi......MORE |
Maraviroc matches boosted protease inhibitor treatment over 96 weeksMichael Carter | 6 years ago Treatment with maraviroc (Celsentri/Selzentry) is associated with durable HIV suppression and a fav......MORE |
What is going on in gay men’s lives when they acquire HIV?Roger Pebody | 6 years ago Gay men in England who have recently become HIV positive describe a complex web of factors which ma......MORE |
No new HIV infections among Kaiser PrEP users, but data shows missed opportunitiesLiz Highleyman | 6 years ago No new HIV infections have occurred among nearly 5000 people who started Truvada for pre-exposure p......MORE |
Lipids improved by switching from ritonavir to cobicistat as a booster for darunavirMichael Carter | 6 years ago Switching from ritonavir to cobicistat is associated with significant improvements in cholesterol a......MORE |
Case reports of severe dolutegravir-related depressionMichael Carter | 6 years ago Severe depression can be a side-effect of treatment with the anti-HIV drug dolutegravir. In HIV Med......MORE |
Experts concur that intermittent oral PrEP probably won’t work for womenGus Cairns | 6 years ago Two presentations at the recent International AIDS Society Conference on HIV Science (IAS 2017) in ......MORE |
Experts concur that event-related oral PrEP probably won’t work for womenGus Cairns | 6 years ago Two presentations at the recent International AIDS Society Conference on HIV Science (IAS 2017) in ......MORE |
Taking dolutegravir in the morning may avert insomniaKeith Alcorn | 6 years ago Italian doctors say that sleeplessness after taking the integrase inhibitor dolutegravir occurred m......MORE |
The availability of direct-acting antivirals is reducing disparities in the uptake of hepatitis C treatmentRoger Pebody | 6 years ago An analysis from British Columbia, Canada shows that older people, individuals with HIV co-infectio......MORE |
The availability of directly acting antivirals is reducing disparities in the uptake of hepatitis C treatmentRoger Pebody | 6 years ago An analysis from British Columbia, Canada shows that older people, individuals with HIV co-infectio......MORE |
Who are trans women acquiring HIV from?Gus Cairns | 6 years ago There is a lot we don’t know about trans women’s HIV risk, why they are so vulnerable to HIV an......MORE |
One in seven people offered PrEP in African study start it immediatelyGus Cairns | 6 years ago One in seven (14%) of people offered PrEP in a large community study of enhanced HIV testing and tr......MORE |
What is “successful ageing” for people living with HIV?Roger Pebody | 6 years ago When Canadian researchers asked HIV-positive people over the age of 50 how they would define “suc......MORE |
New South Wales reports record drop in HIV diagnoses: fewest this year since records beganGus Cairns | 6 years ago Australia’s most populous state, New South Wales (NSW), has reported a steep drop in HIV diagnose......MORE |
No evidence of reduced efficacy or increased side-effects when patients switch to generic drugs, comparison study findsRoger Pebody | 6 years ago An analysis of 440 people switched to generic antiretroviral drugs at an Italian clinic and a match......MORE |
Trans women wary of antiretroviral drug and hormone interactionsLiz Highleyman | 6 years ago Transgender women living with HIV may be hesitant to use antiretroviral therapy (ART) or not take i......MORE |
Liver fibrosis speeds up around the menopause in women with HIV and HCV co-infectionMichael Carter | 6 years ago Menopause is associated with accelerated liver fibrosis in women with HIV and hepatitis C virus (HC......MORE |
People with HIV are at risk for liver fibrosis and steatosisLiz Highleyman | 6 years ago Metabolic syndrome, type 2 diabetes and obesity are risk factors for the development of liver fibro......MORE |
Switching from efavirenz to raltegravir leads to significant improvements in fatty liver disease in people with HIVMichael Carter | 6 years ago Switching to raltegravir from efavirenz is associated with significant improvements in liver steato......MORE |
Peripheral artery disease more common in people with HIV with lower CD4 countsKeith Alcorn | 6 years ago Peripheral artery disease, one of the most common forms of cardiovascular disease, occurs more freq......MORE |
PrEP use in US exceeds 100,000 in Gilead pharmacy surveyLiz Highleyman | 6 years ago An estimated 120,000 people in the US have started Truvada for pre-exposure prophylaxis (PrEP) sinc......MORE |
Incidence of anal cancer has already peaked among HIV-positive gay men; reductions can be achieved with expanded ART coverage and screeningMichael Carter | 6 years ago The incidence of anal cancer among HIV-positive gay men peaked in 2009 and will decline substantial......MORE |
Treatment with DAAs reduces the risk of mortality in the first 18 months after the completion of treatmentMichael Carter | 6 years ago For the first time, a large study has demonstrated that treatment with direct-acting antivirals (DA......MORE |
Switch from boosted protease inhibitor to dolutegravir reduces lipids in people with HIV at higher risk of heart diseaseKeith Alcorn | 6 years ago Switching from a boosted protease inhibitor to the integrase inhibitor dolutegravir was associated ......MORE |
Boosted darunavir plus lamivudine matches three-drug regimenKeith Alcorn | 6 years ago A combination of darunavir/ritonavir and lamivudine was just as effective as the same combination p......MORE |
European and US regulators approve AbbVie's new combo for all hepatitis C genotypesLiz Highleyman | 6 years ago The European Commission and the US Food and Drug Administration (FDA) last week approved AbbVie's n......MORE |
PrEP demand in England is rapidly accelerating – and most will want to join the trialGus Cairns | 6 years ago A survey of people currently using pre-exposure prophylaxis (PrEP) has found that PrEP use has rapi......MORE |
Why curing HIV may be like curing cancer – and may be as difficultGus Cairns | 6 years ago For the last few years, a specialist symposium on HIV cure research has preceded the International ......MORE |
What marks out HIV controllers from others?Gus Cairns | 6 years ago What if we are asking the wrong, question, though? What if trying to destroy or at least expose and......MORE |
Can we achieve a complete HIV cure in more patients?Gus Cairns | 6 years ago What all the different approaches discussed in the previous report have in common is to put HIV inf......MORE |
VRC01 antibody can delay but not prevent viral rebound after interruption of early treatmentLiz Highleyman | 6 years ago A broadly neutralising antibody modestly delayed the resurgence of viral replication following inte......MORE |
Long-acting NRTI shows promise for HIV treatment and PrEPLiz Highleyman | 6 years ago A single oral dose of MK-8591, a long-acting antiretroviral in a novel drug class, suppressed HIV f......MORE |
Stillbirth more frequent in women with HIV in UK and Ireland than in general populationCarole Leach-Lemens | 6 years ago The stillbirth rate among women living with HIV in the UK and Ireland from 2007 to 2015 was more th......MORE |
US HIV funding decisions on PEPFAR in 2017 will have critical effect on ability to reach 90-90-90 goalsKeith Alcorn | 6 years ago A withdrawal of United States funding for HIV treatment and prevention in sub-Saharan Africa could ......MORE |
First protease inhibitor combination pill maintains viral suppressionLiz Highleyman | 6 years ago The first once-daily single-tablet regimen containing a protease inhibitor maintained viral suppres......MORE |
Adolescents with HIV do better in more prosperous African countries, even with treatmentCarole Leach-Lemens | 6 years ago Adolescents who acquired HIV perinatally were less likely to die, grew faster and had better immune......MORE |
France’s next PrEP study aims to assess the wider impact of PrEP on the HIV epidemicRoger Pebody | 6 years ago France is launching a new study which will enrol 3000 new pre-exposure prophylxis (PrEP) users over......MORE |
Dutch study finds out whether gay men prefer daily or on-demand PrEPGus Cairns | 6 years ago In Europe, whether through national programmes or in trials, people are more often than not being g......MORE |
Long-acting cabotegravir injection shows promise for HIV preventionLiz Highleyman | 6 years ago A long-acting injectable formulation of cabotegravir given every 8 weeks produces high enough drugs......MORE |
Doravirine combination pill looks good for initial HIV treatmentLiz Highleyman | 6 years ago A single-tablet regimen containing the next-generation NNRTI doravirine reduced HIV viral load as m......MORE |
Acute kidney injury ‘uncommon’ but unpredictable on tenofovir and ritonavirGus Cairns | 6 years ago Doctors need to monitor patients regularly for kidney function if they are taking tenofovir, especi......MORE |
Countries and donors should aim for new $90-$90-$90 target on HIV, hepatitis, TB drug prices, study showsKeith Alcorn | 6 years ago HIV, hepatitis B and C and tuberculosis can each be treated for less than $90 a year where generic ......MORE |
Medical male circumcision for HIV has benefits for women tooRoger Pebody | 6 years ago South African women whose most recent sexual partner was circumcised are less likely to have HIV, s......MORE |
Demonstration projects explore the feasibility of PrEP for adolescents and young women in South AfricaRoger Pebody | 6 years ago One of the first studies to explore the acceptability, safety and use of pre-exposure prophylaxis (......MORE |
Ipergay trial: PrEP still protected people who had less sex and used it less oftenGus Cairns | 6 years ago A substudy of the French Ipergay trial of ‘on-demand’ PrEP has found that PrEP was just as effe......MORE |
Another HIV vaccine efficacy trial will start this yearGus Cairns | 6 years ago A year ago, one of the biggest pieces of prevention news at the Durban International AIDS Conferenc......MORE |
Glecaprevir/pibrentasvir is effective for people with HIV/HCV co-infectionLiz Highleyman | 6 years ago AbbVie's new pangenotypic regimen combining glecaprevir and pibrentasvir cured almost all HIV-posit......MORE |
90-90-90 progress in southern Africa: HIV testing gap needs to be closed in young people and menKeith Alcorn | 6 years ago Three African countries with high burdens of HIV infection are achieving very high levels of HIV tr......MORE |
Can self-testing engage 'hard to reach' men with HIV testing?Roger Pebody | 6 years ago Adding HIV self-testing as an additional option to a door-to-door programme offering HIV testing in......MORE |
Integrase inhibitors not causing higher rates of adverse birth outcomes, Botswana and French studies showCarole Leach-Lemens | 6 years ago Dolutegravir-based antiretroviral therapy (ART) started in pregnancy is as safe as efavirenz-based ......MORE |
New guidance says start HIV treatment within 7 days of diagnosis – but is everyone ready?Keith Alcorn | 6 years ago Everyone diagnosed with HIV should be offered the option to start treatment within seven days of di......MORE |
International study of gay couples reports no transmissions from an HIV-positive partner on treatmentGus Cairns | 6 years ago A study of 343 gay couples, where one partner had HIV and the other did not, has not found a single......MORE |
New integrase inhibitor bictegravir works well for first-line HIV treatmentLiz Highleyman | 6 years ago A single-tablet regimen containing the experimental integrase inhibitor bictegravir was as effectiv......MORE |
Hepatitis C treatment is effective and feasible in AfricaLiz Highleyman | 6 years ago Treatment for hepatitis C in sub-Saharan Africa can produce cure rates as high as those seen in ind......MORE |
High uptake of HIV self testing by female sex workers in African countriesRoger Pebody | 6 years ago A year ago there was virtually no evidence on the acceptability and feasibility of HIV self testing......MORE |
South African child has controlled HIV off treatment for 8.5 yearsKeith Alcorn | 6 years ago A nine-year-old South African child who was diagnosed with HIV infection at one month of age and r......MORE |
Programme to provide free self tests helps gay men to test for HIV more oftenRoger Pebody | 6 years ago Providing free HIV self-testing kits to gay and bisexual men is an effective way to increase the fr......MORE |
Less frequent clinic visits for HIV care: fine tuning neededKeith Alcorn | 6 years ago Shifts to less frequent clinic visits and medication pick-ups to free up healthcare resources and ......MORE |
Improved treatment for cryptococcal meningitis in HIV could save thousands of lives – if generic drug becomes availableKeith Alcorn | 6 years ago Urgent action is needed to improve access to the antifungal drug flucytosine, say investigators, fo......MORE |
Swaziland: new infections halved in five years as HIV treatment scales upKeith Alcorn | 6 years ago New HIV infections have halved in Swaziland since 2011 at the same time as the proportion of people......MORE |
Long-acting cabotegravir + rilpivirine injection shows good results at 96 weeksLiz Highleyman | 6 years ago Two long-acting injectable antiretrovirals, cabotegravir and rilpivirine, administered once every 4......MORE |
London gonorrhoea rates fall, and HIV rates falling in Australia as more join PrEP demoGus Cairns | 6 years ago Gonorrhoea diagnoses among gay men attending the largest STI clinic in the UK at 56 Dean Street in ......MORE |
World on track to reach the 90-90-90 targets for HIV treatment by 2020Keith Alcorn | 6 years ago The world is on track to reach global targets for reducing AIDS deaths and HIV treatment access by ......MORE |
WHO recommends package of tests, treatment and prevention for 'urgent need' people with HIV with low CD4 countsKeith Alcorn | 6 years ago A new package of measures to ensure rapid initiation of antiretroviral treatment and diagnosis of o......MORE |
Few people with HIV starting raltegravir and dolutegravir change therapy because of side-effectsMichael Carter | 6 years ago Only a few people starting an integrase inhibitor discontinue the treatment during the first year o......MORE |
US regulator approves Gilead's Vosevi combo pill for hepatitis C retreatmentLiz Highleyman | 6 years ago On 18 July the US Food and Drug Administration (FDA) approved Gilead Sciences' Vosevi, a new once-d......MORE |
US regulators approves Gilead's Vosevi combo pill for hepatitis C re-treatmentLiz Highleyman | 6 years ago On July 18 the US Food and Drug Administration (FDA) approved Gilead Sciences' Vosevi, a new once-d......MORE |
Many people living with HIV at high risk of cardiovascular disease are not on statinsMichael Carter | 6 years ago Only half of HIV-positive patients at a Chicago clinic eligible for statin therapy according to the......MORE |
People treated with atazanavir had lower risk of stroke and heart attackKeith Alcorn | 6 years ago People who started HIV treatment with a drug combination containing atazanavir (Reyataz) were signi......MORE |
Gay men using HIV self-tests promptly seek confirmatory testing and linkage to care, New York data suggestsRoger Pebody | 6 years ago Data from the partner services programme in New York City suggests that gay men who have previously......MORE |
Proton pump inhibitors may blunt CD4 cell gains, cause immune activation, in people with HIVKeith Alcorn | 6 years ago Proton pump inhibitors should be used with caution in people with HIV, US researchers say, after fi......MORE |
Non-alcoholic fatty liver disease common in people living with HIV – metabolic disorders are key risk factorsMichael Carter | 6 years ago Over a third of people with HIV have non-alcoholic fatty liver disease (NAFLD) in the absence of he......MORE |
High uptake of home-based HIV testing in Zambia, but repeat visits needed to get close to universal coverageRoger Pebody | 6 years ago Preliminary results from PopART, a large-scale study of a universal test and treat approach to slow......MORE |
Frailty is associated with loss of bone mineral density in middle-aged HIV-positive men and womenMichael Carter | 6 years ago Frailty is associated with loss of bone mineral density (BMD) in HIV-positive people, investigators......MORE |
Curing hepatitis C improves diabetes controlKeith Alcorn | 6 years ago Curing hepatitis C infection with direct-acting antiviral treatment improves diabetes control in pe......MORE |
Viral load as low as 400 copies/ml six months after starting ART is associated with a significant ten-year mortality riskMichael Carter | 6 years ago A viral load as low as 400 copies/ml six months after starting HIV therapy is associated with a sub......MORE |
Hepatitis A oubreak in gay and bisexual men in Europe is growingKeith Alcorn | 6 years ago New cases of hepatitis A cases have soared in Western Europe over the past six months as a result o......MORE |
Hepatitis A outbreak in gay and bisexual men in Europe is growingKeith Alcorn | 6 years ago New cases of hepatitis A cases have soared in Western Europe over the past six months as a result o......MORE |
San Francisco task force releases first hepatitis C estimatesLiz Highleyman | 6 years ago End Hep C SF, a consortium of public health workers, medical providers, advocates and people living......MORE |
Study identifies serious gaps in treatment and care of HIV-positive adolescents in sub-Saharan AfricaMichael Carter | 6 years ago Healthcare providers in sub-Saharan Africa are struggling to provide services for HIV-positive adol......MORE |
Why are women lost from HIV care during pregnancy? Malawi study shows social support and counselling are criticalKeith Alcorn | 6 years ago Lack of social support after diagnosis and inadequate counselling about HIV treatment and HIV disc......MORE |
HIV drug resistance becoming more common in Zambian infantsKeith Alcorn | 6 years ago The proportion of infants with HIV who had drug resistance at the time of HIV diagnosis almost doub......MORE |
New pangenotypic hepatitis C drug combinations recommended for approval in the European UnionKeith Alcorn | 6 years ago Two new pangenotypic direct-acting antiviral combinations have received positive opinions from the ......MORE |
Many Western European countries close to achieving UNAIDS 90-90-90 targetsMichael Carter | 6 years ago Countries in Western and Southern Europe are well on their way to meeting the UNAIDS 90-90-90 targe......MORE |
HIV has a similar impact to diabetes on heart disease riskKeith Alcorn | 6 years ago Living with HIV carries the same lifetime risk of cardiovascular disease as having diabetes, even a......MORE |
Researchers say rule out depression, anxiety, unemployment and other stresses before blaming cognitive impairment for everyday difficultiesMichael Carter | 6 years ago One in five people living with HIV in a European study reported a decline in everyday functioning a......MORE |
Risk score can identify which HIV-positive people with controlled viral load are at greatest risk of neurocognitive declineMichael Carter | 6 years ago Four factors are associated with neurocognitive decline in people living with HIV with an undetecta......MORE |
Experts question Cochrane review of hepatitis C treatmentKeith Alcorn | 6 years ago A systematic review of hepatitis C direct-acting antiviral studies published by the Cochrane Collab......MORE |
HIV drug resistance testing not a priority for resource-limited settings, trial findsKeith Alcorn | 6 years ago Resistance testing is unlikely to improve the effectiveness of second-line HIV treatment in resourc......MORE |
Fractures occur at an earlier age among men with HIVMichael Carter | 6 years ago The incidence of fractures begins to rise a full decade earlier in HIV-positive men compared to the......MORE |
High prevalence of tobacco use among HIV-positive individuals in low- and middle-income countriesMichael Carter | 6 years ago There is a high prevalence of tobacco use among HIV-positive adults in low- and middle-income count......MORE |
Taking PrEP has a profound impact on gay men’s sexual health and wellbeingRoger Pebody | 6 years ago Men who have sex with men (MSM) in Seattle who had recently begun to take pre-exposure prophylaxis ......MORE |
Swiss Grindr survey finds 50% want to use PrEP in the next six monthsGus Cairns | 6 years ago A survey of Swiss gay men and men who have sex with men recruited through the Grindr networking app......MORE |
Point-of-care CD4 counts improve linkage to HIV care in KenyaKeith Alcorn | 6 years ago Carrying out a point-of-care CD4 count immediately after a person was diagnosed with HIV by home-ba......MORE |
MSM, especially if HIV-positive, have an increased risk of meningococcal disease, according to US researchMichael Carter | 6 years ago Men who have sex with men (MSM) have an increased risk of meningococcal disease, investigators from......MORE |
Belgium, Portugal and Brazil will provide PrEP through their health services; Morocco announces a PrEP studyGus Cairns | 6 years ago In the last two weeks, several countries have announced that they will soon launch pre-exposure pro......MORE |
Six-question risk score can identify HIV-positive gay men needing testing for acute hepatitis CRoger Pebody | 6 years ago Six questions can identify HIV-positive gay men who are at elevated risk of having acute (recent) h......MORE |
Young women in Zimbabwe in sexual relationships with older men have an especially high risk of infection with HIVMichael Carter | 6 years ago Young women in Zimbabwe have an especially high risk of infection with HIV if they have a sexual pa......MORE |
HIV treatment targets for people who inject drugs will be missed without focus on rights, privacy and prisonsSusie McLean | 6 years ago Reaching ambitious HIV treatment targets for people who use drugs requires efforts to protect priv......MORE |
High frequency of recurrent high-grade pre-cancerous anal lesions in HIV-positive MSMMichael Carter | 6 years ago A high proportion of HIV-positive men who have sex with men (MSM) successfully treated for high-gra......MORE |
Agreements with cash incentives boost patient adherence to HIV therapy and rates of viral suppressionMichael Carter | 6 years ago Patients who enter into a contract with their HIV healthcare provider to receive cash incentives in......MORE |
Heroin combined with fentanyl is driving overdose crisis in USLiz Highleyman | 6 years ago New sources of heroin and increasing adulteration with fentanyl and other stronger analogues are co......MORE |
Injecting drug use increases worldwide, but no increases in needle and syringe programmesSusie McLean | 6 years ago Despite reports of expanding rates of injecting drug use in a new list of countries around the worl......MORE |
Indonesian buyers club helps people obtain generic hepatitis C treatmentLiz Highleyman | 6 years ago A community-led buyers club in Indonesia has helped more than 100 people get generic direct-acting ......MORE |
Pet care can connect people to health and harm reduction servicesLiz Highleyman | 6 years ago Providing free veterinary care can be a good way to bring homeless and marginally housed people int......MORE |
Use of psychedelic drugs may reduce the risk of suicide in female sex workersLiz Highleyman | 6 years ago Women sex workers who used psychedelic drugs such as LSD were less likely to think about or attempt......MORE |
People with HIV have impaired respiratory health, even when viral load is undetectableMichael Carter | 6 years ago HIV-positive people have impaired respiratory health, even when they have viral suppression with an......MORE |
Canadian Minister of Health opens International Harm Reduction conference amid controversy over overdose deathsSusie Mclean | 6 years ago The 25th International Harm Reduction Conference (HR17) in Montréal, Canada, kicked off with a dra......MORE |
People who use drugs may use cannabis and drug cocktails as a form of harm reductionLiz Highleyman | 6 years ago People who use drugs have come up with innovative strategies that help them reduce harm, including ......MORE |
Many physicians are wary of providing HIV PrEP for young peopleLiz Highleyman | 6 years ago Only about a third of family practice and paediatric providers said they would be likely to prescri......MORE |
Hepatitis C virus reinfection is uncommon after being cured with DAAsLiz Highleyman | 6 years ago Most people on opiate substitution therapy were successfully treated for hepatitis C with an interf......MORE |
Overamping is a common problem among people who use stimulantsLiz Highleyman | 6 years ago Overdosing on stimulants such as methamphetamine – known as 'overamping' – is an under-recognis......MORE |
Combining drug addiction treatment and perinatal HIV prevention leads to good outcomes in KenyaLiz Highleyman | 6 years ago An integrated programme offering medication-assisted drug addiction treatment and services aimed at......MORE |
Hydromorphone works as well as heroin-assisted drug addiction treatmentLiz Highleyman | 6 years ago Hydromorphone was as effective as pharmaceutical heroin for opioid addiction treatment, but it was ......MORE |
Drug checking reveals high levels of fentanyl contamination in Vancouver street drugsLiz Highleyman | 6 years ago A pilot project to check the purity of drugs at Vancouver's Insite safe injection facility found th......MORE |
AA amyloidosis is an unrecognised problem among people who inject drugsLiz Highleyman | 6 years ago AA amyloidosis, a condition resulting from skin and soft tissue infections that can lead to kidney ......MORE |
Life expectancy now near-normal in people with CD4 counts over 350 a year after starting therapyGus Cairns | 6 years ago A large study of 88,504 people with HIV on antiretroviral therapy (ART), published in the Lancet jo......MORE |
Protease inhibitor drug suppresses HIV in semen more slowly than drugs from other classesGus Cairns | 6 years ago Protease inhibitors may not be the best class of drug for people newly diagnosed with HIV to start ......MORE |
MDR-TB numbers could keep growing despite improved treatmentKeith Alcorn | 6 years ago Up to one-in-three tuberculosis cases in Russia could be multidrug resistant by 2040, and one-in-ei......MORE |
MDR TB numbers could keep growing despite improved treatmentKeith Alcorn | 6 years ago Up to one in three tuberculosis cases in Russia could be multi-drug resistant by 2040, and one in e......MORE |
Switching from efavirenz to lopinavir/ritonavir has no meaningful impact on neurological function, says UK studyMichael Carter | 6 years ago Switching from efavirenz does not significantly improve the neurological function of patients takin......MORE |
Undocumented migrants more likely to be lost to follow-up and have poor virological outcomes after starting ART, Milan study confirmsMichael Carter | 6 years ago Undocumented migrants living with HIV have especially poor rates of retention in care and virologic......MORE |
Besifovir and tenofovir exalidex look promising as new hepatitis B drugsLiz Highleyman | 6 years ago Two investigational nucleotide analogue antivirals were shown to be active against hepatitis B viru......MORE |
Naloxone is a heath intervention that can’t be effectively provided without the knowledge and social connections of people who inject drugsRoger Pebody | 6 years ago Programmes to provide naloxone, a drug that reverses the effects of opiate overdose, are successful......MORE |
Fear of stigma is prompting young South Africans to seek early HIV treatmentKeith Alcorn | 6 years ago Young South Africans are strongly motivated to seek HIV testing and treatment by a desire to mainta......MORE |
Increased screening for syphilis boosts detection of early latent infections among Australian gay menMichael Carter | 6 years ago Increased syphilis testing among gay men increased detection of early latent infections and was acc......MORE |
Avoiding false positives: rapid HIV tests vary in their accuracy, so need to be used in combinationRoger Pebody | 6 years ago An evaluation of eight widely used rapid diagnostic tests used in a variety of African countries by......MORE |
Triple combination cures most hepatitis C patients with prior DAA treatment failureLiz Highleyman | 6 years ago Almost all people with genotype 1 hepatitis C who were previously unsuccessfully treated with a cou......MORE |
Early ART highly acceptable and achieves excellent rates of viral suppression among young South African womenMichael Carter | 6 years ago Early antiretroviral therapy (ART) is highly acceptable to the majority of young women with HIV in ......MORE |
EASL releases updated hepatitis B guidelines at International Liver CongressLiz Highleyman | 7 years ago The European Association for the Study of the Liver (EASL) presented revised clinical practice guid......MORE |
Switching to TAF for hepatitis B improves kidney function and bone lossLiz Highleyman | 7 years ago People with hepatitis B who switched from the old tenofovir disoproxil fumarate (TDF) to the new te......MORE |
A quarter of people with second-line ART treatment failure in Kenya have exhausted current treatment optionsMichael Carter | 7 years ago Affordable third-line antiretrovirals are urgently needed in resource-limited settings, according t......MORE |
A quarter of people taking antiretroviral therapy in Kenya have exhausted current treatment optionsMichael Carter | 7 years ago Affordable third-line antiretrovirals are urgently needed in resource-limited settings, according t......MORE |
Generic hepatitis C drugs continue to produce high cure ratesKeith Alcorn | 7 years ago Treatment with generic versions of direct-acting antiviral drugs continues to produce similar cure ......MORE |
Switching from Atripla to generic-containing regimens can produce large cost savingsMichael Carter | 7 years ago Switching from branded Atripla to regimens that include at least one generic drug formulation can a......MORE |
AbbVie combination cures 97% of genotype 3 hepatitis CKeith Alcorn | 7 years ago AbbVie's pangenotypic direct-acting antiviral combination of two drugs cured 97% of people with ear......MORE |
AbbVie combination cures 95% of genotype 3 hepatitis CKeith Alcorn | 7 years ago AbbVie's pangenotypic direct-acting antiviral combination of two drugs cured 95% of people with ear......MORE |
New AbbVie hepatitis C combination cures 99% of people with cirrhosisKeith Alcorn | 7 years ago A new pangenotypic direct-acting antiviral combination developed by AbbVie is highly effective in ......MORE |
Direct-acting antivirals for hepatitis C not linked to higher liver cancer risk in most studiesLiz Highleyman | 7 years ago People with hepatitis C who take treatment with direct-acting antivirals (DAAs) do not appear to ha......MORE |
European HCV treatment access survey shows big variations in eligibilityKeith Alcorn | 7 years ago England, Malta, Slovakia, Hungary and Croatia have the tightest restrictions on who can receive dir......MORE |
Curing hepatitis C reduces cardiovascular riskKeith Alcorn | 7 years ago Curing hepatitis C reduces the risk of cardiovascular events in people with compensated cirrhosis,......MORE |
Monitoring of progress towards 90-90-90 blighted by poor quality reportingMichael Carter | 7 years ago Only six countries, representing just 2% of the global HIV burden, have high quality data reporting......MORE |
Hepatitis C treatment can be provided successfully at syringe programme sitesLiz Highleyman | 7 years ago Administering direct-acting antiviral therapy for people who inject drugs at a syringe exchange sit......MORE |
Study shows that HIV-positive nursing mothers in London can struggle to obtain and afford formula milkMichael Carter | 7 years ago Many HIV-positive nursing mothers in London are struggling to meet the financial costs of formula f......MORE |
Black HIV-positive MSM in US still have lower rates of ART useMichael Carter | 7 years ago The proportion of newly diagnosed HIV-positive men who have sex with men (MSM) in the United States......MORE |
Homeless US military veterans have high rates of HIV, HCV and HBVMichael Carter | 7 years ago Homeless veterans in the United States have a significantly higher prevalence of infection with HIV......MORE |
Behaviour change interventions in HIV prevention: is there still a place for them?Gus Cairns | 7 years ago A meta-analysis of studies of brief interventions to reduce HIV risk behaviour in HIV-negative gay ......MORE |
London data show that hepatitis C is passed on during anal sex without a condomRoger Pebody | 7 years ago Around one in five HIV-positive gay men who recently acquired hepatitis C report anal sex without a......MORE |
PrEP is approved in ScotlandGus Cairns | 7 years ago The Scottish Medicines Consortium (SMC) today announced that it had accepted tenofovir disoproxil/e......MORE |
Health system navigators didn't improve ART initiation or TB treatment completion rates among people newly diagnosed with HIV in DurbanMichael Carter | 7 years ago An intervention using health system navigators, phone support and text message reminders did not im......MORE |
Suicide accounts for 2% of deaths in people with HIV, twice the rate of the general populationRoger Pebody | 7 years ago Men living with HIV have an elevated rate of suicide, particularly in the first year after diagnosi......MORE |
The large fall in HIV diagnoses in London gay men is real and thanks to combination prevention, not just PrEPRoger Pebody | 7 years ago The number of new HIV diagnoses in gay men attending five key London clinics fell substantially dur......MORE |
Tracking down patients lost to HIV care: home visits need to be carefully targetedKeith Alcorn | 7 years ago Efforts to track patients lost to care are likely to produce very little return on the money and ti......MORE |
PrEP should be given to all breastfed babies, researchers sayGus Cairns | 7 years ago An international group of researchers involved in the ANRS 12174 randomised controlled trial of pre......MORE |
Poppers linked to increased risk of some cancers in older MSM without HIVKeith Alcorn | 7 years ago Daily or weekly use of poppers over a number of years is associated with a substantial increase in ......MORE |
Poppers linked to increased risk of some cancers in older men who have sex with men without HIVKeith Alcorn | 7 years ago Daily or weekly use of poppers over a number of years is associated with a substantial increase in ......MORE |
Co-infection with HCV increases cancer risk for people with HIVMichael Carter | 7 years ago People with HIV and hepatitis C virus (HCV) co-infection have an increased risk of non-AIDS-definin......MORE |
Black gay men still at higher risk of HIV in the UKRoger Pebody | 7 years ago Gay and bisexual men of black ethnicity are disproportionately likely to be living with diagnosed H......MORE |
Warning of hepatitis A outbreak among men who have sex with men in EuropeKeith Alcorn | 7 years ago An outbreak of hepatitis A in Europe has affected 287 people in at least 13 countries, with large ......MORE |
Investigating late HIV diagnoses as serious incidents may spur change across the health systemRoger Pebody | 7 years ago Investigating cases of very late HIV diagnosis through the NHS’ serious incident reporting proces......MORE |
Nurse-led intervention improves adherence to ART and is cost-effectiveMichael Carter | 7 years ago An antiretroviral therapy (ART) adherence support study conducted in the Netherlands has been haile......MORE |
Bone density improves in people who switch from tenofovir DF to tenofovir alafenamideLiz Highleyman | 7 years ago After three years, tenofovir alafenamide (TAF) for first-line HIV treatment was better at suppressi......MORE |
Scotland reports its lowest number of HIV diagnoses since 2003Gus Cairns | 7 years ago A report released on Tuesday by Health Protection Scotland shows that last year saw the lowest numb......MORE |
Two-thirds of people with HIV/HCV co-infection in Southeast Asia in need of HCV therapyMichael Carter | 7 years ago Almost two-thirds of people with HIV/hepatitis C virus (HCV) co-infection in Asia are in need of HC......MORE |
Research helps explain how vedolizumab antibody therapy leads to sustained viral remissionLiz Highleyman | 7 years ago HIV and its monkey cousin SIV can carry the alpha-4 beta-7 integrin receptor in their outer envelop......MORE |
Fewer clinic visits improve retention in HIV care in ZambiaKeith Alcorn | 7 years ago People with HIV who attended their clinic once every six months were much less likely to miss their......MORE |
Harm reduction should address the specific needs of couples who inject drugsRoger Pebody | 7 years ago The sharing of drug injecting equipment most often occurs between sexual partners, but the ways in ......MORE |
Vietnam will struggle to meet 90-90-90 targets without addressing barriers to HIV care for men who have sex with menRoger Pebody | 7 years ago Men who have sex with men in Vietnam risk being left behind as the country strives to achieve UNAID......MORE |
Finding men with HIV – and keeping them in treatmentKeith Alcorn | 7 years ago Specialised services to attract men to HIV testing and treatment may need to adopt several differen......MORE |
Linkage to HIV care still challenging for young men, Botswana study findsKeith Alcorn | 7 years ago Almost one in five people newly diagnosed with HIV in a study employing active methods to link peop......MORE |
Several new candidates in HIV drug pipeline discussed at conferenceLiz Highleyman | 7 years ago This year's Conference on Retroviruses and Opportunistic Infections (CROI 2017), held last month i......MORE |
Studies look at brain and cognitive changes in people with HIV as they ageLiz Highleyman | 7 years ago People with HIV often show persistent signs of cognitive impairment and abnormalities in brain stru......MORE |
Early adherence to ART key to long-term virological outcomesMichael Carter | 7 years ago Adherence to antiretroviral therapy (ART) in the first few months after starting treatment is cruci......MORE |
'Test and treat' study shows second phase is finding more people with HIV and getting them onto treatmentKeith Alcorn | 7 years ago After a second wave of intensive household testing, a large study of the 'test and treat' strategy ......MORE |
Glecaprevir/pibrentasvir for hepatitis C can be safely administered with common antiretroviralsLiz Highleyman | 7 years ago AbbVie's investigational glecaprevir/pibrentasvir treatment for hepatitis C is not expected to inte......MORE |
Dolutegravir monotherapy fails to maintain HIV viral suppression, but dolutegravir + lamivudine looks goodLiz Highleyman | 7 years ago Dolutegravir used alone without other antiretrovirals was unable to keep viral load suppressed in s......MORE |
DAA therapy cures most people with HIV/HCV co-infection with decompensated cirrhosis or liver transplantsLiz Highleyman | 7 years ago People with HIV/hepatitis C virus (HCV) co-infection with liver cirrhosis or liver failure, and th......MORE |
D:A:D study – long-term use of darunavir/ritonavir modestly increases the risk of cardiovascular diseaseMichael Carter | 7 years ago Long-term use of the protease inhibitor darunavir/ritonavir modestly increases the risk of cardiova......MORE |
Simple risk score can identify gay men who may have acute HIV infectionRoger Pebody | 7 years ago Seven simple questions about symptoms and risk factors identified three-quarters of gay men in Amst......MORE |
Researchers report case of bone marrow transplant patient off ART for 288 days without HIV reboundLiz Highleyman | 7 years ago An HIV-positive bone marrow transplant recipient at the Mayo Clinic experienced prolonged viral rem......MORE |
New HIV capsid inhibitors show high potency and prolonged activity in early studiesLiz Highleyman | 7 years ago A novel type of antiretroviral drug that interferes with the assembly and disassembly of the HIV ca......MORE |
HIV’s milder cousin may be less mild than previously thoughtGus Cairns | 7 years ago HIV-2’s virulence may have been underestimated and although progression to AIDS and death in HI......MORE |
Integrase inhibitors may increase risk of IRIS in late presenters for HIV treatmentKeith Alcorn | 7 years ago HIV integrase inhibitors such as dolutegravir and raltegravir may increase the risk of immune recon......MORE |
What is safe sex now? Does it include undetectable viral load and PrEP?Roger Pebody | 7 years ago Treatment as prevention and PrEP provide new ways to safely avoid HIV, but this poses challenges to......MORE |
Are people with HIV and HCV co-infection who are cured of hepatitis C with DAAs at increased risk for liver cancer?Liz Highleyman | 7 years ago People with HIV and hepatitis C virus (HCV) co-infection who are successfully treated for hepatitis......MORE |
Bacterial vaginosis does not affect efficacy of oral PrEP in womenGus Cairns | 7 years ago Research presented at the Conference on Retroviruses and Opportunistic Infections (CROI 2017) found......MORE |
STI rates in PrEP users very high, but evidence that PrEP increases them is inconclusiveGus Cairns | 7 years ago A study of PrEP users presented at the Conference on Retroviruses and Opportunistic Infections (CRO......MORE |
Monoclonal antibodies show promise for HIV-positive people with limited treatment optionsLiz Highleyman | 7 years ago A pair of long-acting monoclonal antibodies that prevent HIV from entering human cells – ibalizum......MORE |
No evidence of risk compensation after circumcision in three African cohortsRoger Pebody | 7 years ago Three large studies in South Africa, Zimbabwe and Kenya have found no evidence that men who have be......MORE |
Accelerated linkage to HIV care improves retention in care by a thirdCarole Leach-Lemens | 7 years ago Close to 60% of adults benefiting from point-of-care CD4 cell count testing at HIV testing sites, a......MORE |
Better depression care could improve outcomes for HIV treatment programmesRoger Pebody | 7 years ago Improved management of depression and other mental health disorders has the potential to improve th......MORE |
Peer navigators improve linkage to HIV care and retention in care in South African studyCarole Leach-Lemens | 7 years ago Adults recently diagnosed with HIV getting help from peers to address personal barriers to care tog......MORE |
Prednisone reduces the risk of developing TB-IRIS after starting antiretroviral treatmentKeith Alcorn | 7 years ago Prednisone reduces the risk of an immune restoration inflammatory syndrome (IRIS) in people with HI......MORE |
Will there be a new wave of HIV in people who inject drugs in the US?Gus Cairns | 7 years ago Ever since there was an outbreak of HIV among white, largely rural heroin users in Indiana in 2015,......MORE |
Will there be a new wave of HIV in injecting drug users in the US?Gus Cairns | 7 years ago Ever since there was an outbreak of HIV among white, largely rural heroin users in Indiana in 2015,......MORE |
New NNRTI doravirine shows good efficacy in phase 3 studyLiz Highleyman | 7 years ago Doravirine, an investigational next-generation non-nucleoside reverse transcriptase inhibitor (NNRT......MORE |
Time spent by US HIV patients in care with a transmissible viral load has fallen by three-quarters since 2000Gus Cairns | 7 years ago A study by the US Centers for the Disease Control (CDC) presented at the recent Conference on Retro......MORE |
Time spent by people in HIV care in US with a transmissible viral load has fallen by three-quarters since 2000Gus Cairns | 7 years ago A study by the US Centers for Disease Control and Prevention (CDC) presented at the recent Conferen......MORE |
One in five ‘heterosexual’ men in the UK caught their HIV from another manGus Cairns | 7 years ago A genetic analysis of a large database of UK people with HIV in care shows that 18% of men with HIV......MORE |
When science, community and political will come together, we can end the epidemic, says New York commissionerRoger Pebody | 7 years ago New York City’s strategy to end the AIDS epidemic is firmly rooted in science, was developed in c......MORE |
Spanish vaccine induces viral control off ART in nearly 40% of recipientsGus Cairns | 7 years ago A so-called ‘HIV Conserv’ vaccine has, for the first time, produced significant prolonged viral......MORE |
New hepatitis C infections among HIV-positive gay men drop by half after direct-acting antiviral roll-out in NetherlandsLiz Highleyman | 7 years ago A little more than a year after the Netherlands instituted a policy allowing unrestricted access to......MORE |
Three-drug regimen beats XDR-TB in first trialKeith Alcorn | 7 years ago A regimen of three oral drugs given for six months was enough to clear XDR-TB in 29 of the first 31......MORE |
How should HIV self-testing services be provided?Roger Pebody | 7 years ago Chairing a session on HIV self-testing at the 2017 Conference on Retroviruses and Opportunistic In......MORE |
Stopping smoking cuts the risk of some cancers quickly in people with HIVKeith Alcorn | 7 years ago Smoking probably contributes far more to the risk of cardiovascular disease in people with HIV than......MORE |
Unique case of PrEP failure without drug resistance reported from AmsterdamGus Cairns | 7 years ago HIV pre-exposure prophylaxis (PrEP) appears to be nearly 100% effective if taken consistently so th......MORE |
New HIV infections fall in the US, but demographic and geographic disparities persistLiz Highleyman | 7 years ago The number of annual new HIV infections in the US fell by 18% overall since 2008, offering evidence......MORE |
Isoniazid preventive treatment reduces the risk of death by 37% in people living with HIVKeith Alcorn | 7 years ago A six-month course of isoniazid preventive treatment (IPT) at the beginning of the Temprano trial r......MORE |
Treatment or watchful waiting for cervical abnormalities in women with HIV?Carole Leach-Lemens | 7 years ago Close monitoring of earlier-stage cervical abnormalities (CIN-2) may be preferable to treatment for......MORE |
Tenofovir/emtricitabine/efavirenz less likely to cause adverse birth outcomes than other regimens, Botswana study findsCarole Leach-Lemens | 7 years ago Infants exposed to an antiretroviral regimen of tenofovir, emtricitabine and efavirenz (Atripla) fr......MORE |
Tenofovir/FTC/efavirenz less likely to cause adverse birth outcomes than other regimens, Botswana study findsCarole Leach-Lemens | 7 years ago Infants exposed to an antiretroviral (ART) regimen of tenofovir, emtricitabine and efavirenz (TDF/F......MORE |
Experimental STI prophylaxis in PrEP users produces big drops in syphilis and chlamydia infections but not in gonorrhoeaGus Cairns | 7 years ago Use of the antibiotic doxycycline as on-demand post-exposure prophylaxis by men who have sex with m......MORE |
Changes in viral suppression over time reveal disparities in HIV care in the United StatesLiz Highleyman | 7 years ago Sustained viral suppression over the course of a year may be a better measure than the most recent ......MORE |
Dual antiretroviral regimen maintains durable HIV suppression after switchLiz Highleyman | 7 years ago People who switched from standard antiretroviral therapy to a two-drug regimen of dolutegravir (Tiv......MORE |
Infants treated within days of birth can clear HIV reservoir rapidlyKeith Alcorn | 7 years ago Viral load and viral DNA fall rapidly in infants who begin antiretroviral therapy within days of bi......MORE |
Treatment-as-prevention study sees substantial levels of transmitted drug resistance in participants, but no impact on treatmentGus Cairns | 7 years ago A study of the prevalence of transmitted drug resistance in participants in the ANRS 12249 trial of......MORE |
Point-of-care test improves infant HIV diagnosis rate, treatment starts and retention in careKeith Alcorn | 7 years ago Using a point-of-care test to diagnose HIV in infants significantly improved retention in care, spe......MORE |
Integrase inhibitor bictegravir matches dolutegravir for first-line HIV treatmentLiz Highleyman | 7 years ago Bictegravir, an investigational integrase inhibitor from Gilead Sciences, was highly potent, well t......MORE |
A benign circle: how a combination of factors has reduced HIV infections in one of the hardest-hit parts of AfricaGus Cairns | 7 years ago HIV incidence has started to tumble in one of the best-studied groups of people in Africa, the Conf......MORE |
Men from Latin America and central Europe now outnumber sub-Saharan Africans in HIV diagnoses in European migrantsGus Cairns | 7 years ago The latest figures from the European Centre for Disease Control (ECDC), presented at the recent HIV......MORE |
Across western Europe, migrants from all parts of the world start HIV treatment laterRoger Pebody | 7 years ago An analysis of over 150,000 people living with HIV in eleven western European countries shows that ......MORE |
Living with diagnosed HIV infection for a long time is associated with poor quality of lifeMichael Carter | 7 years ago Longer time living with diagnosed HIV infection is strongly associated with depression, anxiety and......MORE |
Sustained reductions in sexual risk behaviour following couples’ HIV testingRoger Pebody | 7 years ago A programme of couples’ HIV testing and counselling in Zambia appears to result in durable reduct......MORE |
Delays in linkage to care after HIV diagnosis pose the biggest barrier to treatment accessKeith Alcorn | 7 years ago Following individuals through the cascade of care, from HIV diagnosis to treatment and undetectable......MORE |
Women significantly more likely than men to have suboptimal adherence to HIV therapyMichael Carter | 7 years ago Women are more likely than men to have poor adherence to combination antiretroviral therapy (cART),......MORE |
Legalisation of sex work associated with lower prevalence of HIV in sex workersRoger Pebody | 7 years ago Countries that have legalised some aspects of sex work have fewer sex workers living with HIV than ......MORE |
High hepatitis C prevalence seen in Amsterdam PrEP study participantsGus Cairns | 7 years ago Researchers from the Dutch PrEP demonstration study, AmPrEP, have found an unexpectedly high rate o......MORE |
Recreational drug use very common among HIV-positive Londoners admitted for inpatient careMichael Carter | 7 years ago Recent recreational drug use is highly prevalent among HIV-positive people admitted to inpatient ca......MORE |
Recreational drug use very common among HIV-positive Londoners admitted for in-patient careMichael Carter | 7 years ago Recent recreational drug use is highly prevalent among HIV-positive people admitted to in-patient c......MORE |
Curing hepatitis C reduces the risk of diabetes & kidney failure in people with HIV/HCV co-infectionKeith Alcorn | 7 years ago Curing hepatitis C infection substantially reduces the risk of developing type 2 diabetes in people......MORE |
Hope overshadowed – the US PrEP SummitGus Cairns | 7 years ago The US National HIV PrEP Summit, which took place in early December in San Francisco, was one of th......MORE |
Liver cirrhosis and decompensation still on the rise among people with hepatitis CLiz Highleyman | 7 years ago Complications of advanced liver disease including cirrhosis and hepatic decompensation have risen o......MORE |
Two-thirds of HIV clinics in the UK don't think there's a current need for specialist services for older HIV-positive patientsMichael Carter | 7 years ago Two-thirds of HIV clinics in the UK do not think there is a current need for specialist care servic......MORE |
Is DAA treatment for hepatitis C reducing the need for liver transplants?Liz Highleyman | 7 years ago People successfully treated for hepatitis are less likely to need liver transplants and less likely......MORE |
No new HIV infections in Northern California Kaiser PrEP programme, but STI rates risingLiz Highleyman | 7 years ago No new HIV infections have been seen among nearly 1000 people who started Truvada for pre-exposure ......MORE |
Starting treatment quickly after diagnosis is not harmful for adolescents, Zimbabwe study findsKeith Alcorn | 7 years ago A lack of lengthy preparation before starting HIV treatment does not result in an increased risk of......MORE |
High prevalence of low testosterone among younger and middle-aged ART-treated men in FranceMichael Carter | 7 years ago Around one in six young and middle-aged HIV-positive men doing well on antiretroviral therapy (ART)......MORE |
Regular small incentives can improve adherence to ARTMichael Carter | 7 years ago The provision of regular low-value economic incentives can improve adherence to antiretroviral ther......MORE |
What are the key steps to effective delivery of PrEP care?Roger Pebody | 7 years ago Providing pre-exposure prophylaxis (PrEP) to people who need it entails at least nine key steps, wh......MORE |
Many older people living with HIV in the UK worried about poverty, loneliness and social careRoger Pebody | 7 years ago People over the age of 50 now represent one third of all people living with HIV, but the social car......MORE |
Vitamin D deficiency reduces statin potency, increases risk of muscle pain in people with HIVKeith Alcorn | 7 years ago People living with HIV who take statins are less likely to experience cholesterol reductions and mo......MORE |
Tenofovir alafenamide approved for hepatitis B in EuropeLiz Highleyman | 7 years ago The European Commission this week granted marketing authorisation for tenofovir alafenamide, to be ......MORE |
ART-treated patients in UK have an accurate understanding of their viral loadMichael Carter | 7 years ago The vast majority of antiretroviral (ART)-treated patients in the UK have an accurate knowledge of ......MORE |
People taking ART in the UK have an accurate understanding of their viral loadMichael Carter | 7 years ago The vast majority of people taking antiretroviral therapy (ART) in the UK have an accurate knowledg......MORE |
Implants and injectables: PrEP in the futureKeith Alcorn | 7 years ago Last month’s announcement that the Bill and Melinda Gates Foundation will give up to $140 million......MORE |
Risk of pregnancy loss among smokers much higher for women with HIVMichael Carter | 7 years ago Smoking “dramatically” increases the risk of pregnancy loss – miscarriage or stillbirth – i......MORE |
Risk score accurately predicts which pregnant and postpartum women would benefit most from PrEPMichael Carter | 7 years ago A risk score based on routine assessments carried out during antenatal care in resource-limited set......MORE |
Nearly two-thirds of European HIV cases are now in RussiaGus Cairns | 7 years ago The annual number of new cases of HIV increased by at least 8% in 2015 in the whole of the World He......MORE |
Scaling up adult male circumcision calculated to have HIV prevention benefits additional to those seen with 90-90-90 treatment targetMichael Carter | 7 years ago Scale-up of voluntary medical male circumcision (VMMC) in countries with a high HIV prevalence has ......MORE |
Viral load rebounds in a third of women who start HIV therapy during pregnancy or postpartum, South African study showsMichael Carter | 7 years ago Approximately one-third of HIV-positive women who attain viral suppression after starting antiretro......MORE |
Viral load testing capacity still weak in sub-Saharan Africa, 7-country study findsKeith Alcorn | 7 years ago Viral load testing capacity is still weak in some of the countries with the highest burden of HIV i......MORE |
People with HIV/HCV co-infection at increased risk of kidney disease and bone disordersMichael Carter | 7 years ago Hepatitis C virus (HCV) infection in people with HIV co-infection is associated with an increased r......MORE |
Virologic failure detected in a quarter of ART-treated children in TanzaniaMichael Carter | 7 years ago A quarter of children and adolescents in Tanzania taking antiretroviral therapy (ART) have major re......MORE |
The UK’s largest sexual health clinic saw a 40 percent drop in new HIV infections this yearGus Cairns | 7 years ago The clinic at 56 Dean Street in Soho, central London, the largest sexual health clinic in the UK, s......MORE |
In the era of universal treatment, what are HIV clinical guidelines for?Gus Cairns | 7 years ago The purpose and structure of clinical HIV guidelines may have to change radically now that universa......MORE |
African Americans taking ART have high incidence of illness associated with risk of cardiovascular diseaseMichael Carter | 7 years ago Black HIV-positive men and women receiving antiretroviral therapy (ART) have especially high rates ......MORE |
Co-morbidities are common and rising among people with HIV in the USLiz Highleyman | 7 years ago People living with HIV are increasingly experiencing a range of non-AIDS-related comorbidities as t......MORE |
High prevalence of resistance to zidovudine among people in sub-Saharan Africa experiencing virological failure with tenofovir-containing ARTMichael Carter | 7 years ago A significant proportion of people with virological failure after treatment with tenofovir-containi......MORE |
Migration and age differences between male and female partners fuelling the HIV epidemic in South AfricaRoger Pebody | 7 years ago Analyses from two large household surveys in KwaZulu-Natal, South Africa shed new light on the dyna......MORE |
Multiple motivations for ‘transactional sex’ need to be taken into account when planning interventions for African womenRoger Pebody | 7 years ago Many HIV prevention strategies identify ‘transactional sex’ as a practice that contributes to y......MORE |
Malawi, Zambia and Zimbabwe making strong progress towards the 90-90-90 goalsKeith Alcorn | 7 years ago Malawi, Zambia and Zimbabwe are making strong progress towards achieving the treatment and viral su......MORE |
Almost half of MSM with HIV/HCV co-infection have HCV in their rectal fluidMichael Carter | 7 years ago Almost half of HIV-positive men who have sex with men (MSM) who have co-infection with hepatitis C ......MORE |
Sofosbuvir-based therapy achieves excellent SVR12 rates among people who inject drugs in the UkraineMichael Carter | 7 years ago People who inject drugs (PWID) can have an excellent response to sofosbuvir-based therapy for hepat......MORE |
Sofosbuvir-based therapy achieves excellent SVR12 rates among people who inject drugs in UkraineMichael Carter | 7 years ago People who inject drugs (PWID) can have an excellent response to sofosbuvir-based therapy for hepat......MORE |
United States: Syringe service use up, but a third of people who inject drugs still share needlesLiz Highleyman | 7 years ago Use of syringe exchange and distribution services has increased substantially over the past decade ......MORE |
Electronic monitoring of antiretroviral adherence in "real time" boosts pill taking and need for intensive adherence supportMichael Carter | 7 years ago Electronic monitoring of antiretroviral adherence in “real time” significantly increases the pr......MORE |
Electronic monitoring of antiretroviral adherence in "real-time" boosts pill taking and need for intensive adherence supportMichael Carter | 7 years ago Electronic monitoring of antiretroviral adherence in “real time” significantly increases the pr......MORE |
Hepatitis C virus infection is rising among gay and bisexual men in San DiegoLiz Highleyman | 7 years ago The prevalence of hepatitis C virus (HCV) infection among HIV-positive men who have sex with men in......MORE |
NHS England announces major new PrEP trial for 2017Gus Cairns | 7 years ago NHS England, in collaboration with Public Health England, has announced in a press release today th......MORE |
Survey finds good knowledge of PrEP in Europe and a considerable amount of unsupported informal PrEP useGus Cairns | 7 years ago A large survey of knowledge and use of pre-exposure prophylaxis (PrEP) in Europe released its preli......MORE |
There may be fewer people living with undiagnosed HIV in the UK than previously thoughtRoger Pebody | 7 years ago Public Health England’s estimate of the number of people who have HIV without being aware of it h......MORE |
CDC releases new data on HIV diagnosis and prevalence in the United StatesLiz Highleyman | 7 years ago In advance of World AIDS Day the US Centers for Disease Control and Prevention (CDC) released its l......MORE |
Ending the HIV epidemic faces daunting barriers, former WHO HIV chief warnsGus Cairns | 7 years ago The difficulty of bringing the HIV epidemic “down to zero” should not be underestimated, Kevin ......MORE |
World Health Organization urges scale-up of HIV self-testingRoger Pebody | 7 years ago HIV self-testing (sometimes called ‘home testing’) should be offered as an additional approach ......MORE |
Health agencies should challenge the idea that most gay men use drugsRoger Pebody | 7 years ago Drug use generally and chemsex more specifically are perceived to be common and normalised behaviou......MORE |
Sofosbuvir/ledipasvir is effective for people with HIV/HCV co-infection in real-world clinical practiceLiz Highleyman | 7 years ago The sofosbuvir/ledipasvir (Harvoni) co-formulation used in real-world clinical practice produced go......MORE |
Sofosbuvir/ledipasvir is effective for HIV/HCV co-infected people in real-world clinical practiceLiz Highleyman | 7 years ago The sofosbuvir/ledipasvir (Harvoni) coformulation used in real-world clinical practice produced goo......MORE |
Grazoprevir triple regimen demonstrates high cure rates, even for hard-to-treat peopleLiz Highleyman | 7 years ago A new three-drug co-formulation containing Merck's grazoprevir plus the investigational agents MK-3......MORE |
People with HIV/HCV co-infection see good cure rates in real-world practice in MadridLiz Highleyman | 7 years ago More than 90% of HIV-positive people treated with direct-acting antivirals for hepatitis C – incl......MORE |
Chemsex and slamming “suffused with romantic, emotional and communal attachments”Roger Pebody | 7 years ago While gay men’s use of drugs in sexual contexts is often portrayed as deviant, extreme and unconn......MORE |
8-week triple DAA combo cures most people with genotype 1-6 hepatitis CLiz Highleyman | 7 years ago A three-drug regimen of sofosbuvir, velpatasvir and voxilaprevir taken for 8 weeks demonstrated an ......MORE |
Birth cohort screening and linkage to care for HCV treatment still weak in United StatesKeith Alcorn | 7 years ago Grave weaknesses in hepatitis C screening and linkage to care are still widespread in the United St......MORE |
AbbVie pangenotypic combination cures 98% or above across genotypesKeith Alcorn | 7 years ago AbbVie’s combination of glecaprevir and pibrentasvir cured at least 98% of people with hepatitis ......MORE |
AbbVie pangenotypic combination cures almost all hard-to-treat people with HCV genotype 3Keith Alcorn | 7 years ago AbbVie’s pangenotypic combination of glecaprevir and pibrentasvir cured almost all of the hardest......MORE |
US Veterans Affairs and Australia show potential for rapid elimination of hepatitis CKeith Alcorn | 7 years ago If sufficient money is available to pay for direct-acting antivirals (DAAs), the US Veterans Affair......MORE |
Tenofovir alafenamide approved for hepatitis B, works well with less effect on bonesLiz Highleyman | 7 years ago Tenofovir alafenamide (TAF), a new lower-dose pro-drug, matches the older tenofovir disoproxil fuma......MORE |
Self-sampling for HIV testing popular with gay men who have not recently tested, but less uptake by African peopleRoger Pebody | 7 years ago Three quarters of those using England’s free self-sampling service are men who have sex with men,......MORE |
Long term decline in consistent condom use among Australian gay menRoger Pebody | 7 years ago Data from the last ten years of the Australian Gay Community Periodic Surveys shows a steady declin......MORE |
Grazoprevir/elbasvir + sofosbuvir highly effective for hard-to-treat genotype 3 hepatitis C patientsLiz Highleyman | 7 years ago A triple regimen of grazoprevir/elbasvir (Zepatier) plus sofosbuvir (Sovaldi) without ribavirin cur......MORE |
Liver cancer risk reduced after hepatitis C treatment, but vigilance needed for aggressive cancers in months after treatmentKeith Alcorn | 7 years ago People who are cured of hepatitis C after a course of direct-acting antiviral treatment do not hav......MORE |
Real-world responses to HCV treatment among US veterans match best clinical trial resultsKeith Alcorn | 7 years ago Direct-acting antiviral treatment is curing people of hepatitis C infection in clinics at similar r......MORE |
The ‘long tail’ problem: injected-PrEP trial will be extended due to persistence of drug in companion studyGus Cairns | 7 years ago A study presented at last month’s HIV Research for Prevention (HIVR4P) conference in Chicago show......MORE |
The ‘long tail’ problem: forthcoming injected-PrEP efficacy trial delayed due to persistence of drug in some volunteersGus Cairns | 7 years ago A study presented at last month’s HIV Research for Prevention (HIVR4P) conference in Chicago show......MORE |
NHS England loses appeal – it must consider providing PrEPRoger Pebody | 7 years ago At the Court of Appeal in London this morning, three judges confirmed that NHS England is responsib......MORE |
Tenofovir alafenamide works well and improves kidney and bone markers in older people living with HIVLiz Highleyman | 7 years ago A co-formulation of tenofovir alafenamide (TAF) plus emtricitabine, used with a third antiretrovir......MORE |
Omega-3 fatty acids may reduce triglycerides and improve inflammation in people with HIVLiz Highleyman | 7 years ago Long-term use of omega-3 fatty acid supplements was associated with reduced levels of triglycerides......MORE |
Smoking more harmful than HIV for people taking effective treatment, US study suggestsKeith Alcorn | 7 years ago Smoking has the potential to shorten the life of a person taking HIV treatment by an average of six......MORE |
Dolutegravir regimen highly effective in clinical trial for womenLiz Highleyman | 7 years ago A once-daily regimen containing the potent HIV integrase inhibitor dolutegravir worked better than......MORE |
Ibalizumab monoclonal antibody looks promising for people with drug-resistant HIVLiz Highleyman | 7 years ago Ibalizumab, an experimental monoclonal antibody with a unique mechanism of action, demonstrated goo......MORE |
Men with HIV and men on PrEP in Boston see large increase in sexually transmitted infectionsLiz Highleyman | 7 years ago Rates of gonorrhoea, syphilis and chlamydia have risen steeply at Fenway Health in Boston since 201......MORE |
Four days on, three days off HIV treatment controls viral load in French pilot studyKeith Alcorn | 7 years ago An experimental `four days on, three days off` antiretroviral regimen kept viral load fully suppre......MORE |
Do people living with HIV who have an undetectable viral load need to wear condoms?Liz Highleyman | 7 years ago In the face of extensive research showing that people living with HIV who are on antiretroviral the......MORE |
Electronic health records can help select candidates for HIV PrEPLiz Highleyman | 7 years ago A machine learning algorithm used to analyse electronic health records (EHRs) identified high-risk ......MORE |
Darunavir/ritonavir & lamivudine matches triple-drug therapyKeith Alcorn | 7 years ago Simplifying antiretroviral therapy to a two-drug combination of lamivudine plus the protease inhibi......MORE |
Only a small proportion of gay men with HIV receive anal cancer screeningLiz Highleyman | 7 years ago In the absence of national screening guidelines, only 11% of HIV-positive gay and bisexual men in t......MORE |
New long-acting fusion inhibitor albuvirtide plus boosted protease inibitor matches standard triple-drug therapyKeith Alcorn | 7 years ago A new fusion inhibitor, albuvirtide, under development in China, combined with a boosted protease i......MORE |
Generic hepatitis C drugs purchased online achieve high cure ratesKeith Alcorn | 7 years ago Use of generic versions of direct-acting antivirals resulted in very high cure rates for people who......MORE |
Tests of online PrEP purchases by London clinic find no fakes, and adequate drug levelsGus Cairns | 7 years ago A sexual health clinic in central London that offered to test drug levels in users of tenofovir/emt......MORE |
The benefit of treatment has outweighed the clinical impact of lipodystrophy, conference hearsGus Cairns | 7 years ago The 2016 Glasgow HIV Conference heard today that over a 20-year period, people who suffered lipodys......MORE |
French study reveals the growing complexity of medical needs as people with HIV ageKeith Alcorn | 7 years ago The complexity of the needs of people living with HIV will continue to increase as the population a......MORE |
Dolutegravir and central nervous system side-effects: abacavir, older age increase the riskKeith Alcorn | 7 years ago Insomnia, dizziness, headache and other central nervous system side effects are occurring more freq......MORE |
Some of the Americans who need PrEP the most face the greatest barriers to getting itRoger Pebody | 7 years ago The personal values and moral judgements of healthcare providers are likely to interfere with the a......MORE |
Two-drug HIV therapy just as effective as three-drug therapyKeith Alcorn | 7 years ago Simplification of an antiretroviral treatment to a boosted protease inhibitor and the nucleoside an......MORE |
As PrEP knowledge increases in San Francisco, 12,500 people now thought to be on PrEPLiz Highleyman | 7 years ago Knowledge about and use of HIV pre-exposure prophylaxis (PrEP) has greatly increased over the past ......MORE |
New $90-$90-$90 target needed for global viral hepatitis, HIV and TB treatmentKeith Alcorn | 7 years ago The costs of making drugs to treat viral hepatitis, HIV and TB are now so low that each disease cou......MORE |
New HIV prevention products will need marketing and effective health services to reach the people who need themRoger Pebody | 7 years ago There is a naivety among many HIV prevention researchers and advocates about the steps needed to in......MORE |
Huge diversity in current HIV vaccine research, Research for Prevention conference hearsGus Cairns | 7 years ago The HIV vaccine research field is currently going through probably its most fertile and diverse per......MORE |
New microbicide enema achieves high levels of drug in rectal tissues in monkeysGus Cairns | 7 years ago Rectal microbicides that protect against HIV transmission via anal sex are a bigger technical chall......MORE |
Rings, films or inserts? Researchers need to develop prevention products that make sense in women’s livesRoger Pebody | 7 years ago “We need to think outside of the box,” Sharon Hillier of the Microbicide Trials Network told th......MORE |
Vaginal and rectal bacteria may have a big influence on HIV transmission and microbicide efficacyGus Cairns | 7 years ago A number of presentations at the 2016 HIV Research for Prevention Conference (HIVR4P) in Chicago lo......MORE |
Controlling the HIV epidemic: ambitious funding, expanded workforce, innovations and micro-focus neededKeith Alcorn | 7 years ago Advocates who seek to end AIDS by 2030 should be ready to call on Hillary Clinton to massively incr......MORE |
Policy makers’ inaction is leading people to take PrEP ‘in the wild’Roger Pebody | 7 years ago An increasing number of gay men and others at risk of HIV are seeking to protect their health with ......MORE |
Anal sex may transmit four in ten HIV infections in US women at high riskGus Cairns | 7 years ago A study presented at the 2016 HIV Research for Prevention (HIVR4P) Conference in Chicago, USA sugge......MORE |
Second case report of PrEP failure due to drug-resistant virusRoger Pebody | 7 years ago A PrEP user in New York City has become HIV positive with virus that is resistant to Truvada and ot......MORE |
Mental health disorders common among people with HIV in British ColumbiaMichael Carter | 7 years ago Over 50% of people with HIV, many from disenfranchised groups, in British Columbia, Canada, are liv......MORE |
Crohn’s disease drug produces long-lasting viral undetectability and T-cell restoration off treatment in monkeysGus Cairns | 7 years ago In a promising experiment in rhesus macaque monkeys, scientists from Emory University in Atlanta ha......MORE |
Doctors in Netherlands observe higher than expected dolutegravir treatment discontinuation rateMichael Carter | 7 years ago Almost one in seven people in a Dutch clinic population stopped treatment with the HIV integrase in......MORE |
Less than 100% adherence to HIV therapy, even with viral suppression, can lead to more inflammation and immune activationMichael Carter | 7 years ago Research involving men taking antiretroviral therapy, all with an undetectable viral load, has show......MORE |
Educational attainment associated with health outcomes after starting HIV therapyMichael Carter | 7 years ago People with HIV who have lower educational attainment have poorer outcomes after starting combinati......MORE |
No evidence that contaminated nelfinavir led to increased risk of birth abnormalities or cancerMichael Carter | 7 years ago HIV-negative infants potentially exposed in utero to doses of the HIV protease inhibitor nelfinavir......MORE |
Promising trends continue in UK diagnosis and treatment ratesGus Cairns | 7 years ago A ‘mini report’ of the latest figures on HIV diagnoses, late diagnosis, and treatment uptake in......MORE |
Hepatitis B testing should be done before hepatitis C treatment due to risk of HBV reactivationLiz Highleyman | 7 years ago People considering direct-acting antiviral (DAA) therapy for hepatitis C should first be tested for......MORE |
Gay men with overlapping partnerships are more likely to be recently and locally infectedGus Cairns | 7 years ago A study analysing transmission patterns between gay men in a cohort of patients on San Diego, Calif......MORE |
100% cure rate for people with HCV genotype 1 treated with AL-335, odalasvir and simeprevir for 6 or 8 weeksLiz Highleyman | 7 years ago A triple regimen containing two experimental hepatitis C drugs – AL-335 and odalasvir – plus si......MORE |
Young people say that sex and relationships education in schools is negative and out of touchRoger Pebody | 7 years ago A review of 55 separate studies of sex and relationships education (SRE) in schools shows that youn......MORE |
Media reports of a British HIV cure 'breakthrough' are prematureKeith Alcorn | 7 years ago The Sunday Times yesterday reported that HIV had become undetectable in the blood of one man takin......MORE |
Hepatitis C infection and reinfection among men who have sex with men need higher priority, US and European studies showLiz Highleyman | 7 years ago Public health officials in Michigan have identified a cluster of more than 20 cases of apparently s......MORE |
Syphilis rates rising among gay men in US, CDC data showLiz Highleyman | 7 years ago New state-level data reveal that syphilis cases continue to rise among gay and bisexual men in the ......MORE |
Risk of reinfection is a concern after successful hepatitis C treatmentLiz Highleyman | 7 years ago People on opiate agonist substitution therapy can be successfully treated with grazoprevir/elbasvir......MORE |
Dutch model finds PrEP for high-risk gay men is cost-effective at current prices and cost-saving at generic pricesGus Cairns | 7 years ago A mathematical modelling study based on the HIV epidemic in the Netherlands has found that daily Pr......MORE |
EASL issues new hepatitis C treatment recommendations for all genotypesLiz Highleyman | 7 years ago The European Association for the Study of the Liver (EASL) released its latest recommendations on t......MORE |
Structural inequalities create vulnerability to HIV for black gay men in New YorkRoger Pebody | 7 years ago The sexual relationships of many African American men who have sex with men are largely shaped by e......MORE |
Early infant HIV testing at birth and at 6 weeks of age will save lives, extend life expectancy and is cost-effective for South Africa, study findsMichael Carter | 7 years ago Early infant HIV diagnosis in South Africa will save lives, extend life expectancy and be cost-effe......MORE |
Spanish study gives reassurance: small HIV blips do not predict treatment failureMichael Carter | 7 years ago A very low viral load (20-49 copies/ml) during HIV therapy does not increase the risk of the subseq......MORE |
HCV treatment is effective and may work as prevention for people who inject drugsLiz Highleyman | 7 years ago Hepatitis C treatment for people who inject drugs is as safe and effective as it is for non-drug-us......MORE |
New York clinic outlines how to improve uptake of PrEP by transgender peopleRoger Pebody | 7 years ago Dedicated efforts are needed to engage transgender men and women with clinical services and to enco......MORE |
Ugandan experience shows TB detection can be successfully incorporated into community HIV testing campaignsMichael Carter | 7 years ago Community health campaigns provide an opportunity to detect previously undiagnosed cases of tubercu......MORE |
Where would gay men prefer to take their next HIV test?Roger Pebody | 7 years ago Among English gay men who have never previously taken a test for HIV, self-testing and self-samplin......MORE |
Hepatitis C vaccine development shows progress but scientific barriers remainLiz Highleyman | 7 years ago An effective vaccine may be necessary to eliminate hepatitis C virus (HCV) but development has been......MORE |
Sweden the first country to achieve UNAIDS/WHO 90-90-90 targetMichael Carter | 7 years ago Sweden has become the first country to achieve the UNAIDS/WHO 90-90-90 target, research published i......MORE |
Managing non-communicable diseases among people living with HIVTheo Smart | 7 years ago Non-communicable diseases - including cardiovascular diseases, diabetes, cancers, and other illnes......MORE |
Delays in updating HIV treatment guidelines in Africa blocking early treatment for millionsKeith Alcorn | 7 years ago Delays in adopting the World Health Organization’s 2015 recommendation of HIV treatment for all t......MORE |
Effective antiviral treatment reduces fatigue in people with chronic hepatitis CLiz Highleyman | 7 years ago Fatigue – a common symptom among people living with hepatitis C virus (HCV) infection – is asso......MORE |
INHSU 2016 opens with focus on hepatitis C prevention and treatment for people who inject drugsLiz Highleyman | 7 years ago The 5th International Symposium on Hepatitis Care in Substance Users (INHSU 2016) got underway yest......MORE |
London gay men anticipate some pros and cons of different PrEP methods – but optimal efficacy is key to acceptabilityRoger Pebody | 7 years ago When presented with a range of possible HIV prevention technologies – a daily pill, pills before ......MORE |
Acceptability of PrEP for London gay men affected by perception of risk, sexual partners’ attitudes and the stigmatisation of sexRoger Pebody | 7 years ago PrEP is broadly acceptable to London gay men who are at risk of acquiring HIV, with many men seeing......MORE |
Life expectancy of patients starting HIV therapy differs sharply between high and middle/low income countriesMichael Carter | 7 years ago There are significant disparities in the life expectancy of HIV-positive patients starting combinat......MORE |
Life expectancy of people starting HIV therapy differs sharply between high- and middle/low-income countriesMichael Carter | 7 years ago There are significant disparities in the life expectancy of HIV-positive people starting combinatio......MORE |
HIV-positive gay and bisexual men have increased risk of hospitalisation with anxiety and mood disorders, a risk factor for later mortalityMichael Carter | 7 years ago HIV-positive gay and bisexual men are almost ten times more likely to be hospitalised because of mo......MORE |
Statins reduce risk of progression to cirrhosis in people with HIV/HCV co-infectionMichael Carter | 7 years ago Treatment with statins decreases the risk of progression to liver cirrhosis in people with HIV and ......MORE |
Statins reduce risk of progression to cirrhosis in HIV/HCV-co-infected peopleMichael Carter | 7 years ago Treatment with statins decreases the risk of progression to liver cirrhosis in people co-infected w......MORE |
San Francisco reports new low in HIV infections and faster treatment, but disparities remainLiz Highleyman | 7 years ago On September 1 the San Francisco Department of Public Health released its HIV Epidemiology Annual R......MORE |
Improvements in HIV treatment and care have had no impact on rates of endstage liver disease among HIV-positive people with viral hepatitisMichael Carter | 7 years ago Incidence of endstage liver disease (ESLD) among HIV-positive people with viral hepatitis changed l......MORE |
Improvements in HIV treatment and care have had no impact on rates of endstage liver disease among HIV-positive patients with viral hepatitisMichael Carter | 7 years ago Incidence of endstage liver disease (ESLD) among HIV-positive patients with viral hepatitis changed......MORE |
Vaginal ring for HIV prevention effective and acceptableRoger Pebody | 7 years ago An updated adherence analysis from the ASPIRE study indicates that consistent users of a vaginal ri......MORE |
Study looks at use of PrEP during pregnancy and breastfeedingLiz Highleyman | 7 years ago Women in San Francisco and the New York City frequently chose to use Truvada for pre-exposure prop......MORE |
Realism needed about the benefits and risks of taking part in HIV cure studiesRoger Pebody | 7 years ago A significant proportion of people living with HIV would be willing to take part in a study towards......MORE |
Depression increases risk of heart attack for adults with HIVMichael Carter | 7 years ago Major depression is associated with an increased risk of heart attack for middle-aged HIV-positive ......MORE |
Elevated lipids associated with cognitive decline in middle-aged HIV-positive men doing well on ARTMichael Carter | 7 years ago Elevated cholesterol and a gene associated with Alzheimer’s risk in the general population are bo......MORE |
Elevated lipids associated with cognitive decline in middle aged HIV-positive men doing well on ARTMichael Carter | 7 years ago Elevated cholesterol and a gene associated with Alzheimer’s risk in the general population are bo......MORE |
US PrEP study achieves high levels of engagement and adherence among black men who have sex with menGus Cairns | 7 years ago What was described at the AIDS2016 conference as “The first PrEP trial devised and run by four bl......MORE |
Many people in the US with chronic hepatitis B not being properly monitoredMichael Carter | 7 years ago Many people with chronic hepatitis B (CHB) virus infection have infrequent medical monitoring, acco......MORE |
Neglect of infectious diseases in prisons highlighted at AIDS 2016Theo Smart | 7 years ago “Prisoners are among the most neglected of the key populations; they bear higher burdens of HIV, ......MORE |
HIV not a risk factor for fibrosis progression in people with hepatitis CMichael Carter | 7 years ago HIV co-infection is not associated with accelerated progression of liver fibrosis in people with he......MORE |
New WHO algorithm to prevent TB deaths in very ill people with HIVTheo Smart | 7 years ago The World Health Organization (WHO) has released a new diagnostic algorithm in order to reduce the ......MORE |
German medicines watchdog rejects ‘new tenofovir’ pillGus Cairns | 7 years ago The German health technology assessment agency IQWiG has announced that it finds no advantage in De......MORE |
How can clinical services engage men who have sex with men in Africa?Roger Pebody | 7 years ago Men who have sex with men living in African countries have an extremely high burden of HIV, Stefan ......MORE |
Poor kidney function associated with increased cardiovascular risk for people with HIVMichael Carter | 7 years ago Renal impairment is associated with an increased risk of cardiovascular disease (CVD) in HIV-positi......MORE |
Most contraceptives not linked to HIV infection, but Depo-Provera may raise riskLiz Highleyman | 7 years ago Birth control pills and some types of injectable and implanted contraceptives were not associated w......MORE |
Ongoing hepatitis B virus replication associated with higher mortality for people with HIVLiz Highleyman | 7 years ago People with HIV and hepatitis B virus (HBV) co-infection have more than double the risk of death if......MORE |
Vaginal bacteria increase HIV susceptibility and may reduce PrEP effectivenessLiz Highleyman | 7 years ago Overgrowth of a certain species of vaginal bacteria was associated with a 13-fold higher likelihood......MORE |
Most patients taking second-line ART in sub-Saharan Africa achieve viral suppression but there's a need for third-line treatment optionsMichael Carter | 7 years ago Approximately 85% of patients switched to protease inhibitor-based second-line antiretroviral (ART)......MORE |
Most people taking second-line ART in sub-Saharan Africa achieve viral suppression but there's a need for third-line treatment optionsMichael Carter | 7 years ago Approximately 85% of people switched to protease inhibitor-based second-line antiretroviral (ART) i......MORE |
No new HIV infections seen in San Francisco's Strut PrEP programmeLiz Highleyman | 7 years ago A community-based sexual health clinic in San Francisco has offered nurse-led pre-exposure prophyla......MORE |
Efavirenz appears to be associated with elevated suicide risk in START trialLiz Highleyman | 7 years ago Participants in the START treatment-timing trial who took antiretroviral regimens containing efavir......MORE |
A detectable CMV viral load could signal a high risk of mortality in older individuals hospitalised with HIV-associated TBTheo Smart | 7 years ago A study conducted in a cohort of hospitalised HIV-associated TB coinfected adults from Khayelitsha......MORE |
People shifting from paediatric to adult HIV care have a high risk of ART failureMichael Carter | 7 years ago HIV-positive adolescents and young adults are especially likely to experience the virological failu......MORE |
Patients shifting from paediatric to adult HIV care have a high risk of ART failureMichael Carter | 7 years ago HIV-positive adolescents and young adults are especially likely to experience the virological failu......MORE |
Package of prophylaxis against infections reduces the risk of death for people starting HIV treatment very lateKeith Alcorn | 7 years ago A package of enhanced prophylaxis against infections significantly reduced the risk of death in adu......MORE |
Ending AIDS by 2030 a distant prospect, global HIV incidence, prevalence, treatment coverage and mortality figures suggestMichael Carter | 7 years ago Remarkable progress has been made towards curbing the global HIV epidemic, but there is little chan......MORE |
AbbVie 3D and 2D hepatitis C combos work well for people with HIV and HCV co-infectionLiz Highleyman | 7 years ago AbbVie's paritaprevir-based 3D regimen for hepatitis C virus (HCV) genotype 1 and 2D regimen for ge......MORE |
START analysis looks at who benefits most from immediate HIV treatmentLiz Highleyman | 7 years ago Starting antiretroviral therapy (ART) soon after HIV diagnosis led to better outcomes than delayed ......MORE |
High Court rules NHS England is responsible for funding PrEPKeith Alcorn | 7 years ago A judicial review in the High Court has ruled that NHS England is responsible for funding pre-expos......MORE |
Training community health workers to perform intensified TB case finding associated with a surge in TB diagnoses in a rural Malawi studyTheo Smart | 7 years ago Intensified TB case finding (TB ICF) by community health workers was associated with a dramatic (20......MORE |
Searching for the next ‘Berlin patient’: doctors document bone-marrow recipients with HIVGus Cairns | 7 years ago The ‘Berlin patient’, Timothy Ray Brown, has now survived seven years off antiretroviral therap......MORE |
PrEP rollout recipients in France top 1000: full trial results report 97% effectivenessGus Cairns | 7 years ago Up to July 2016, 1077 people, 96.4% of them gay men, have started HIV pre-exposure prophylaxis (PrE......MORE |
PrEP rollout recipients in France top 1,000: full trial results report 97% effectivenessGus Cairns | 7 years ago Up to July 2016, 1077 people, 96.4% of them gay men, have started HIV pre-exposure prophylaxis (PrE......MORE |
Stigma persists in the undetectable eraRoger Pebody | 7 years ago In an era of widespread HIV treatment and undetectable viral load, stigma remains a persistent feat......MORE |
Reducing clinic visits can support retention in HIV care, African studies showKeith Alcorn | 7 years ago Interventions which reduce the need for people to attend clinics are proving highly successful in r......MORE |
High-dose rifampicin for TB treatment regimen may improve survival in people with low CD4 cell countsTheo Smart | 7 years ago More aggressive TB treatment using high dose of rifampicin, in addition to ARV treatment, could red......MORE |
Early HIV treatment: mothers say they need time to thinkCarole Leach-Lemens | 7 years ago Findings from the first randomised controlled trial to date evaluating postpartum antiretroviral th......MORE |
Mapping local HIV epidemics can help target resources to areas with the greatest needRoger Pebody | 7 years ago Global health agencies have recently put a new emphasis on geography. UNAIDS have called for progra......MORE |
Women with HIV have higher risk of loss to follow-up and death after deliveryCarole Leach-Lemens | 7 years ago Despite the widespread implementation of Option B+ (lifelong antiretroviral therapy (ART) for pregn......MORE |
Phone and home visit follow-up and appointment trackers improve retention in HIV care for pregnant women and new mothersCarole Leach-Lemens | 7 years ago Phone and home visit follow-ups, improved use of appointment books to track attendance and patient-......MORE |
Once-daily raltegravir works as well as twice-daily for initial HIV treatmentLiz Highleyman | 7 years ago A new formulation of the integrase inhibitor raltegravir (Isentress) taken once daily suppressed H......MORE |
Bone loss partially recovers after stopping PrEP, twice-yearly kidney monitoring is enough for mostLiz Highleyman | 7 years ago Young adults taking Truvada for pre-exposure prophylaxis (PrEP) experienced a modest decrease in bo......MORE |
Dolutegravir plus lamivudine dual therapy works well as initial HIV treatmentLiz Highleyman | 7 years ago A two-drug regimen of dolutegravir and the well-tolerated NRTI lamivudine led to sustained viral su......MORE |
Access to HIV home tests doubles the frequency of HIV testing in Australian gay menRoger Pebody | 7 years ago A randomised trial conducted with Australian gay men has shown that easy access to self-testing kit......MORE |
'Test and treat': large study fails to show an impact on new HIV infectionsRoger Pebody | 7 years ago The first major research study of ‘test and treat’ as a public health intervention to report it......MORE |
Earlier HIV treatment is not over-burdening health servicesKeith Alcorn | 7 years ago Earlier treatment initiation is not overwhelming rural health services in South Africa, but changes......MORE |
Long-acting injectable drugs work well for HIV maintenance therapyLiz Highleyman | 7 years ago Two long-acting injectable antiretrovirals – cabotegravir and rilpivirine – administered once e......MORE |
Viral load pilot study shows roll-out will depend on an educated workforceKeith Alcorn | 7 years ago For viral load testing to prevent treatment failure, drug resistance and onward transmission, treat......MORE |
World’s largest study of HIV self-testing gets off the groundRoger Pebody | 7 years ago Early data from STAR, the largest study yet of HIV self-testing, suggests that there is a strong de......MORE |
Australia adopts ambitious plan to use PrEP to ‘virtually eliminate’ HIV by 2020Gus Cairns | 7 years ago Australia plans an ambitious programme of pre-exposure prophylaxis (PrEP) provision for gay men at ......MORE |
Market constraints and uncertainties may limit the scale-up of HIV self-testingRoger Pebody | 7 years ago Four different HIV self-test products are now manufactured and approved for sale in the US and Euro......MORE |
Sofosbuvir/velpatasvir shows high cure rate in HIV/HCV co-infection studyLiz Highleyman | 7 years ago The once-daily co-formulation of sofosbuvir and velpatasvir was highly effective against all hepati......MORE |
Starting treatment on the day of HIV diagnosis improves retention and viral suppression, Haiti study showsKeith Alcorn | 7 years ago Interventions to improve linkage to care and retention in treatment which speed up the start of tre......MORE |
PrEP can further reduce the risk of HIV infection after a partner starts treatmentLiz Highleyman | 7 years ago Offering Truvada pre-exposure prophylaxis (PrEP) to the HIV-negative partner in a serodiscordant c......MORE |
Young gay men can do well on PrEP, but may need more supportLiz Highleyman | 7 years ago Young gay and bisexual men had good adherence to Truvada for pre-exposure prophylaxis (PrEP) during......MORE |
SEARCH study exceeds 90-90-90 targets after 2 years of 'test and treat' for HIV in rural East AfricaKeith Alcorn | 7 years ago A large study that embeds 'test and treat' for HIV within a larger multi-disease prevention campaig......MORE |
South Africa has driven mother-to-child HIV transmission down to 4%Carole Leach-Lemens | 7 years ago Mother-to-child transmission (MTCT) of HIV at population level was just over 4% at 18 months follow......MORE |
HIV will only be cured with combinations too, conference delegates hearGus Cairns | 7 years ago Curing people of HIV infection will have to involve combinations of drugs and approaches, just as H......MORE |
Progress towards 90-90-90 targets in southern Africa: find the men!Keith Alcorn | 7 years ago Studies of treatment cascade performance in South Africa and Namibia show large variations between ......MORE |
Far fewer people drop out of HIV care in South Africa than previously thoughtRoger Pebody | 7 years ago Previous research has considerably over-estimated the number of people living with HIV who stop att......MORE |
HIV criminalisation on the rise, especially in sub-Saharan AfricaLesley Odendal | 7 years ago Globally, 72 countries have adopted laws that specifically allow for HIV criminalisation, either be......MORE |
New strategy aims to end AIDS in children by 2020Keith Alcorn | 7 years ago A new strategy to end paediatric AIDS launched at the 21st International AIDS Conference in Durban,......MORE |
More confidence on zero risk: still no transmissions seen from people with an undetectable viral load in PARTNER studyGus Cairns | 7 years ago The PARTNER study, which two years ago created headlines by establishing that the chance of an HIV-......MORE |
It’s all go for a new HIV vaccine efficacy trial this yearGus Cairns | 7 years ago A new efficacy trial for an HIV vaccine – only the seventh ever conducted in the history of the e......MORE |
Comprehensive services for sex workers reduce detectable viral load, but enhanced ARV services provide no extra benefitRoger Pebody | 7 years ago A randomised trial in female sex workers in Zimbabwe, offering enhanced access to HIV treatment and......MORE |
HIV treatment programmes need to prepare for the 'youth bulge', South African experience showsCarole Leach-Lemens | 7 years ago Treatment programmes in sub-Saharan Africa must prepare for a growing population of adolescents ove......MORE |
PrEP use exceeds 79,000 in US pharmacy survey, but some groups lagging behindLiz Highleyman | 7 years ago More than 79,000 people in the US have started Truvada for pre-exposure prophylaxis (PrEP) over the......MORE |
Strong association between sexual violence and African women acquiring HIV in EuropeRoger Pebody | 7 years ago Migrant African women who have acquired HIV since moving to France are four times more likely to ha......MORE |
Gains in curbing HIV epidemic could be lost without continued commitment, AIDS 2016 speakers sayLiz Highleyman | 7 years ago Participants at the 21st International AIDS Conference (AIDS 2016), taking place this week in Durba......MORE |
TB2016 demands a global commitment to end TBTheo Smart | 7 years ago While much of TB 2016, held on the eve of AIDS 2016 from 16-17 July 2016 was devoted to the rapidly......MORE |
Progress towards 90-90-90 targets is promising, but funding is the critical step, says UNAIDS leaderKeith Alcorn | 7 years ago The 90-90-90 targets for testing, treatment and viral suppression are achievable by 2020 in many hi......MORE |
Young women treated in very early HIV infection stay HIV negative and preserve immune functionGus Cairns | 7 years ago A group of young South African women who were diagnosed in very early infection and immediately giv......MORE |
Shortened regimen for MDR-TB shows good results for childrenLesley Odendal | 7 years ago The use of the shortened 9-month treatment regimen for multidrug-resistant tuberculosis (MDR-TB), k......MORE |
PrEP researchers now focusing on the best ways to get PrEP to people who need itRoger Pebody | 7 years ago Speaking to a pre-conference meeting on pre-exposure prophylaxis (PrEP) yesterday at the 21st Inter......MORE |
Opioid substitution therapy improves many ART-related outcomes among people who inject drugsMichael Carter | 7 years ago Opioid substitution therapy has a key roll in improving antiretroviral therapy (ART)-related outcom......MORE |
Most young MSM and transgender women, including those with HIV, would benefit from HPV vaccinationMichael Carter | 7 years ago Most young gay, bisexual and other men who have sex with men (MSM) would benefit from human papillo......MORE |
Incidence of liver cancer is increasing in patients with HIV/HCV co-infectionMichael Carter | 7 years ago Incidence of liver cancer is increasing among patients with HIV co-infection, an international team......MORE |
Incidence of liver cancer is increasing in people with HIV/HCV co-infectionMichael Carter | 7 years ago Incidence of liver cancer is increasing among people with HIV co-infection, an international team o......MORE |
Switching from tenofovir DF to TAF improves bone and kidney safetyLiz Highleyman | 7 years ago People with HIV who switched from the older tenofovir disoproxil fumarate (TDF) formulation to teno......MORE |
Feasible to prescribe ART to emergency department patients with suspected acute HIV infectionMichael Carter | 7 years ago Empiric antiretroviral therapy (ART) for individuals presenting to emergency departments with suspe......MORE |
HIV seroconversion is rare if Truvada PrEP is used consistentlyLiz Highleyman | 7 years ago New HIV infections occurred at a low rate of about 1 per 100 person-years among people who took dai......MORE |
New integrase inhibitor bictegravir looks promising in early studiesLiz Highleyman | 7 years ago Gilead Sciences' novel integrase inhibitor bictegravir (formerly GS-9883) demonstrated favourable p......MORE |
Atripla three times weekly maintains HIV viral suppression for 24 weeksLiz Highleyman | 7 years ago People with undetectable viral load who switched from taking the Atripla single-tablet regimen (efa......MORE |
VACS Index score can help identify HIV-positive people most at risk of neurocognitive declineMichael Carter | 7 years ago A combination of simple, routine blood tests may be able to predict which people living with HIV ar......MORE |
VACS Index score can help identify HIV-positive patients most at risk of neurocognitive declineMichael Carter | 7 years ago A combination of simple, routine blood tests may be able to predict which HIV-positive patients are......MORE |
Gay and bisexual people really do have poorer mental health, national US health survey showsGus Cairns | 7 years ago The inclusion, for the first time, of a question about sexual orientation in a regularly-conducted ......MORE |
Vaccination could have important role in control of UK HCV epidemic among people who inject drugsMichael Carter | 7 years ago A vaccine, even with low efficacy, could lead to meaningful reductions in the incidence and prevale......MORE |
PRO 140 antibody injections maintain viral suppression in phase 2 studyLiz Highleyman | 7 years ago Subcutaneous injections of PRO 140, a monoclonal antibody that blocks HIV entry into cells, was wel......MORE |
PRO-140 antibody injections maintain viral suppression in phase 2 studyLiz Highleyman | 7 years ago Subcutaneous injections of PRO 140, a monoclonal antibody that blocks HIV entry into cells, was wel......MORE |
US National HIV Testing Day boosts numbers testingRoger Pebody | 7 years ago Today, June 27, is National HIV Testing Day in the United States and a study just published in Morb......MORE |
ART use averting huge numbers of opportunistic infections among children living with HIV in lower-income countriesMichael Carter | 7 years ago There has been a decrease in cases of many opportunistic infections (OIs) among children living wit......MORE |
ART use averting huge numbers of opportunistic infections among HIV-positive children in lower-income countriesMichael Carter | 7 years ago There has been a decrease in cases of many opportunistic infections (OIs) among HIV-positive childr......MORE |
PrEP use is rising fast in US, but large racial disparities remainLiz Highleyman | 7 years ago More than 49,000 people in the US have filled prescriptions for Truvada for pre-exposure prophylaxi......MORE |
Hepatitis C antigen testing could eliminate need for two-step HCV testing, reduce cost of accessKeith Alcorn | 7 years ago Testing for hepatitis C virus core antigen could eventually replace the current two-step procedure......MORE |
Gay men report a wide range of behaviours to make sex saferRoger Pebody | 7 years ago Gay men in the UK employ a wide range of precautionary tactics and behaviours to avoid harms during......MORE |
Many US communities vulnerable to HIV outbreak due to unsafe injecting of prescription opioidsMichael Carter | 7 years ago Research published in the online edition of the Journal of Acquired Immune Deficiency Syndromes has......MORE |
Women in HIV serodiscordant relationships less likely to take PrEP consistently if they experience intimate partner violenceMichael Carter | 7 years ago Experiencing intimate partner violence is associated with an increased risk of poor adherence to HI......MORE |
People who inject drugs have other priorities ahead of PrEPRoger Pebody | 7 years ago People who inject drugs have fundamental concerns about HIV pre-exposure prophylaxis and the manner......MORE |
HIV treatment reduces HIV transmission by 77% in South African couplesKeith Alcorn | 7 years ago Antiretroviral treatment reduced the risk of HIV transmission by 77% in serodiscordant couples in r......MORE |
HIV testing and treatment campaigns need to target women and the under 35s, says research from South AfricaMichael Carter | 7 years ago A quarter of HIV-positive individuals in KwaZulu-Natal are unaware of their infection status, accor......MORE |
Sofosbuvir/ledipasvir regimens can cost less per cure than older hepatitis C treatmentsKeith Alcorn | 7 years ago The cost of treating chronic hepatitis C with sofosbuvir/ledipasvir (Harvoni) is lower than the cos......MORE |
Sofosbuvir/ledipasvir regimens can cost less per cure than older hepatitis C treatmentsLiz Highleyman | 7 years ago The cost of treating chronic hepatitis C with sofosbuvir/ledipasvir (Harvoni) is lower than the cos......MORE |
HIV-positive adolescents need to be rapidly linked to specialist care to have best chances of sustaining engagement with HIV servicesMichael Carter | 7 years ago Adolescents newly diagnosed with HIV need to be rapidly incorporated into HIV care networks to have......MORE |
Adolescents with HIV need to be rapidly linked to specialist care to have best chances of sustaining engagement with HIV servicesMichael Carter | 7 years ago Adolescents newly diagnosed with HIV need to be rapidly incorporated into HIV care networks to have......MORE |
Less frequent CD4 and viral load monitoring safe for people doing well on ARTMichael Carter | 7 years ago The frequency of routine monitoring for people treated with antiretrovirals with viral suppression ......MORE |
Big increases in proportion of HIV-positive patients in US treated with ART and with viral suppressionMichael Carter | 7 years ago The proportion of HIV-positive patients receiving care in the United States who accessed antiretrov......MORE |
Big increases in proportion of HIV-positive people in US treated with ART and with viral suppressionMichael Carter | 7 years ago The proportion of people living with HIV receiving care in the United States who accessed antiretro......MORE |
New HCV therapies unaffordable to health systems and individualsMichael Carter | 7 years ago The pricing of new treatments for hepatitis C virus (HCV) means they are unaffordable for many heal......MORE |
Sub-type C infection does not increase the risk of virologic failure when patients are taking tenofovir-containing first-line ARTMichael Carter | 7 years ago There is no evidence that HIV-positive patients with sub-type C infection have an increased risk of......MORE |
Sub-type C infection does not increase the risk of virologic failure when people are taking tenofovir-containing first-line ARTMichael Carter | 7 years ago There is no evidence that HIV-positive people with sub-type C infection have an increased risk of t......MORE |
UN High-Level Meeting on Ending AIDS faces battle over key populationsKeith Alcorn | 7 years ago Activists say that a United Nations Political Declaration on Ending AIDS, due to be finalised this ......MORE |
HIV self-testing has several advantages, but some barriers to HIV testing likely to remainRoger Pebody | 7 years ago A service offering kits for HIV self-testing in South Africa has the potential to improve uptake of......MORE |
Australia shows an alternative to rationing hepatitis C treatmentKeith Alcorn | 7 years ago The Hepatitis C Trust has announced it is considering seeking judicial review of NHS England's deci......MORE |
Significant attrition at each stage of HIV care cascade in South AfricaMichael Carter | 7 years ago There is significant attrition at each stage of the HIV care continuum in South Africa, according t......MORE |
Cost is biggest barrier to PrEP in Europe, ECDC declaresGus Cairns | 7 years ago A meeting a month ago at the European Centre for Disease Control (ECDC) in Stockholm found that cos......MORE |
Cost is biggest barrier to PrEP in Europe, ECDC report declaresGus Cairns | 7 years ago A meeting a month ago at the European Centre for Disease Control (ECDC) in Stockholm found that cos......MORE |
France to provide universal access to hepatitis C treatmentKeith Alcorn | 7 years ago France will provide access to hepatitis C treatment with direct-acting antivirals to everyone diagn......MORE |
Many South African patients whose HIV has been diagnosed have unprotected sex with a serodiscordant partner before starting ARTMichael Carter | 7 years ago Among a sample of South Africans living with diagnosed HIV infection in South Africa and waiting to......MORE |
Many South African patients whose HIV has been diagnosed have unprotected sex with a serodiscrodant partner before starting ARTMichael Carter | 7 years ago Among a sample of South Africans living with diagnosed HIV infection in South Africa and waiting to......MORE |
Many South African people whose HIV has been diagnosed have unprotected sex with a serodiscordant partner before starting ARTMichael Carter | 7 years ago Among a sample of South Africans living with diagnosed HIV infection in South Africa and waiting to......MORE |
Two million people with HIV started treatment in 2015Keith Alcorn | 7 years ago At least two million people worldwide started antiretroviral treatment in 2015 alone, and 17 millio......MORE |
2 million people with HIV started treatment in 2015Keith Alcorn | 7 years ago At least two million people worldwide started antiretroviral treatment in 2015 alone, and 17 millio......MORE |
Very high levels of drug resistance seen in patients failing first-line antiretroviral therapy in KenyaGus Cairns | 7 years ago A cross-sectional survey of viral load in patients attending the largest clinic providing antiretro......MORE |
Very high levels of drug resistance seen in people experiencing first-line antiretroviral therapy failure in KenyaGus Cairns | 7 years ago A cross-sectional survey of viral load in patients attending the largest clinic providing antiretro......MORE |
Rare but severe liver side-effects reported among South African patients starting efavirenz-based ARTMichael Carter | 7 years ago Treatment with efavirenz has been associated with rare but severe liver complications among patient......MORE |
AIDS patients have increased risk of death due to non-AIDS-related cancersMichael Carter | 7 years ago People diagnosed with AIDS have a very high risk of dying of a non-AIDS-defining cancer, Italian in......MORE |
People diagnosed with AIDS have increased risk of death due to non-AIDS-related cancersMichael Carter | 7 years ago People diagnosed with AIDS have a very high risk of dying of a non-AIDS-defining cancer, Italian in......MORE |
Only treating patients with cirrhosis with DAAs will have limited impact on HCV epidemic in EnglandMichael Carter | 7 years ago Targeting new hepatitis C virus (HCV) direct acting antivirals (DAAs) at patients with cirrhosis wi......MORE |
American gay men’s use of condoms has been falling for a decade, regardless of sero-sorting or PrEPRoger Pebody | 7 years ago There has been a long-term decline in condom use by American gay men, researchers from the Centers......MORE |
American gay men’s use of condoms has been falling for a decade, regardless of serosorting or PrEPRoger Pebody | 7 years ago There has been a long-term decline in condom use by American gay men, researchers from the Centers......MORE |
HIV/HBV co-infection linked to worse immune recovery and death, but tenofovir improves outcomesLiz Highleyman | 7 years ago HIV-positive people with hepatitis B virus (HBV) co-infection had impaired CD4 cell recovery after ......MORE |
Poor mental health more commonly experienced by gay and bisexual men who are younger, poorer, less educated or blackRoger Pebody | 7 years ago While it is well established that men who have sex with men are more likely to experience poor ment......MORE |
In Option B+, side-effects and needing time to think are key reasons for not taking HIV medicationRoger Pebody | 7 years ago A qualitative study of women in Malawi who chose not to take HIV treatment as part of the country......MORE |
Denmark shows first clear evidence of the success of treatment as prevention in gay men in a high income countryGus Cairns | 7 years ago A study by the University of California, Los Angeles, and Copenhagen University Hospital provides t......MORE |
Successful diagnosis of acute/early HIV infections may have contributed to fall in HIV incidence in San DiegoMichael Carter | 7 years ago An HIV testing programme targeting individuals with acute/early infection likely contributed to a d......MORE |
HIV rapidly develops resistance to gene-editing cure technologyGus Cairns | 7 years ago In a setback for a novel approach to curing HIV, researchers involved in a technique that uses enzy......MORE |
Does having HIV affect response to hepatitis C treatment?Liz Highleyman | 7 years ago A study from the US Veterans Health Administration found that HIV-positive people responded as well......MORE |
Hypertension in patients with HIV associated with obesity, fat loss and previous treatment with stavudineMichael Carter | 7 years ago Patients with HIV have a higher prevalence of hypertension than closely matched HIV-negative contro......MORE |
WHO issues new hepatitis C guidelines, EASL guidelines update forthcoming in SeptemberLiz Highleyman | 7 years ago In April, coinciding with the 2016 International Liver Congress in Barcelona, the World Health Orga......MORE |
Men taking virologically suppressive ART have undetectable HIV in their pre-ejaculatory fluidMichael Carter | 7 years ago HIV is undetectable in the pre-ejaculatory fluid of men taking suppressive antiretroviral therapy, ......MORE |
Small risk of sexual transmission of HIV persists through first six months of ARTMichael Carter | 7 years ago A risk of HIV transmission to sexual partners persists for six months after the initiation of antir......MORE |
US on course to end its HIV epidemic – eventuallyGus Cairns | 7 years ago If current trends continue, the US may eventually end its HIV epidemic, a mathematical model recent......MORE |
HCV associated with increased risk of cancers of the head and neckMichael Carter | 7 years ago Infection with hepatitis C virus (HCV) is associated with an increased risk of head and neck cancer......MORE |
Hepatitis C kills more people than any other infectious disease in US, CDC saysLiz Highleyman | 7 years ago The number of deaths due to hepatitis C is at an all-time high in the US and exceeds those attribu......MORE |
Hepatitis C therapy improves quality of life for people who inject drugs, but reinfection risk remainsKeith Alcorn | 7 years ago People on opiate substitution therapy can be successfully treated with grazoprevir/elbasvir (Zepati......MORE |
High prevalence of geriatric conditions in HIV-positive patients aged over 50 in San FranciscoMichael Carter | 7 years ago Older HIV-positive patients have a high prevalence of multiple age-related problems, investigators ......MORE |
China has a long way to go before it achieves 90-90-90 targetsMichael Carter | 7 years ago A study published in Clinical Infectious Diseases suggests that China has a long way to go before i......MORE |
Which men stand to benefit most from access to PrEP?Michael Carter | 7 years ago New data from the PROUD pre-exposure prophylaxis (PrEP) study have identified the characteristics o......MORE |
How do gay men diagnosed with HIV change their risk behaviour?Gus Cairns | 7 years ago To what extent do gay men modify their sexual risk behaviour after testing HIV positive? Two Austra......MORE |
People treated for hepatitis C have unexpectedly high rate of liver cancer recurrenceLiz Highleyman | 7 years ago Hepatitis C patients with cirrhosis who were treated with direct-acting antivirals had about twice ......MORE |
ART use doesn't increase sexual risk among people with HIV in the UKMichael Carter | 7 years ago Taking antiretroviral therapy (ART) is not associated with an increased risk of condomless sex with......MORE |
More targeted interventions to diagnose HIV during acute infection are needed, researchers warnMichael Carter | 7 years ago Men who have sex with men (MSM) diagnosed with HIV in the acute phase of HIV infection have a great......MORE |
Portugal's roll-out of HCV therapy with DAAs achieves impressive resultsMichael Carter | 7 years ago Roll-out of hepatitis C virus (HCV) therapy using direct acting antivirals (DAAs) has achieved exce......MORE |
First data on uptake of HIV self-testing in the UKRoger Pebody | 8 years ago Between April 2015 and February 2016, almost 28,000 people have paid £29.95 for a kit allowing the......MORE |
Opt-out HIV testing in a hospital emergency department may cost less than managing two patients with undiagnosed HIVRoger Pebody | 8 years ago Opt-out HIV testing in accident and emergency departments in areas of high HIV prevalence is likely......MORE |
Considerable overlap between HIV and shigellosis epidemics in the UKMichael Carter | 8 years ago Approximately a third of cases of non-travel-related Shigella dysentery in the UK involve HIV-posit......MORE |
Considerable overlap between HIV and Shigella epidemics in the UKMichael Carter | 8 years ago Approximately a third of cases of non-travel-related Shigella dysentery in the UK involve HIV-posit......MORE |
Online privacy concerns limit the reach of sexual health messages on social mediaRoger Pebody | 8 years ago The way in which individuals manage their identities on Facebook, for example avoiding publication ......MORE |
Multiple social and health factors associated with irregular attendance at London HIV clinicsRoger Pebody | 8 years ago People who miss appointments for HIV care are more likely to have money problems, childcare respons......MORE |
DAAs achieve excellent outcomes in real-world settingsMichael Carter | 8 years ago Hepatitis C virus (HCV) therapy with direct acting antivirals (DAAs) is as effective in real-world ......MORE |
Model suggests there are fewer people with HIV in the US than thought, and more of them on therapyGus Cairns | 8 years ago A study comparing recorded diagnoses of HIV with subsequent records of viral load and CD4 tests sug......MORE |
High incidence of HCV re-infection among HIV-positive MSM in Western EuropeMichael Carter | 8 years ago There is a very high incidence of hepatitis C virus (HCV) re-infection among HIV-positive men who h......MORE |
Sofosbuvir/velpatasvir cures HCV in 95% of people with HCV and HIV co-infectionLiz Highleyman | 8 years ago A dual regimen of sofosbuvir plus velpatasvir was well tolerated and highly effective against hepat......MORE |
Six weeks of sofosbuvir/ledipasvir is enough to cure acute hepatitis C in HIV-negative peopleLiz Highleyman | 8 years ago A regimen of sofosbuvir/ledipasvir (Harvoni) taken for six weeks cured all patients with genotype 1......MORE |
Tenofovir alafenamide works well against hepatitis B with less effect on bones and kidneysLiz Highleyman | 8 years ago The new tenofovir alafenamide (TAF) pro-drug is as potent against hepatitis B virus (HBV) as the cu......MORE |
Low-cost generic hepatitis C drugs match branded products in viral responseKeith Alcorn | 8 years ago Generic versions of direct-acting antivirals purchased from China and India by people unable to obt......MORE |
Shifting hepatitis C treatment to primary care providers could expand availabilityLiz Highleyman | 8 years ago Hepatitis C treatment managed by non-specialists such as primary care physicians and nurse practiti......MORE |
Sofosbuvir/velpatasvir + GS-9857 works well for treatment-experienced hepatitis C patientsLiz Highleyman | 8 years ago A triple combination of Gilead Sciences' sofosbuvir, velpatasvir and GS-9857 demonstrated a high s......MORE |
Hepatitis C treatment may not be enough to stop the progress of advanced liver disease, or reduce liver transplant needKeith Alcorn | 8 years ago Doctors need to have “full and frank” discussions with patients about the potential risks and b......MORE |
$300 hepatitis C combination to enter clinical trialsKeith Alcorn | 8 years ago The Drugs for Neglected Diseases Initiative (DNDI) is launching clinical trials in Thailand and Mal......MORE |
People not taking HIV treatment feel under pressure to ‘do the right thing’Roger Pebody | 8 years ago Australian people living with HIV who have chosen not to take antiretrovirals and who have doubts a......MORE |
Resistance to anti-HIV drugs in steep decline in SwitzerlandMichael Carter | 8 years ago Prevalence of antiretroviral drug resistance has declined significantly among patients in Switzerla......MORE |
Primary care doctors and nurse practitioners can successfully treat people with hepatitis CLiz Highleyman | 8 years ago Direct-acting antiviral therapy for hepatitis C delivered by non-specialists such as primary care p......MORE |
A third of MSM with HIV/HCV co-infection have HCV in their semenMichael Carter | 8 years ago Hepatitis C virus (HCV) is present in the semen of a third of co-infected HIV-positive men who have......MORE |
VRC01 antibody delays but does not prevent HIV rebound after antiretroviral treatment interruptionLiz Highleyman | 8 years ago VRC01, a broadly neutralising antibody targeting HIV's CD4 binding site, was able to modestly delay......MORE |
More people with HIV are achieving viral suppression in US, but about 40% remain above transmission thresholdsLiz Highleyman | 8 years ago A growing proportion of people with HIV are reaching an undetectable viral load on antiretroviral t......MORE |
Indian study proves that more people virally suppressed in a population equals fewer HIV infectionsGus Cairns | 8 years ago The proportion of people living with HIV in a population who have a detectable viral load is much m......MORE |
Simple outreach on dating websites increases HIV testing rateRoger Pebody | 8 years ago A simple online outreach intervention – in which a health educator engaged in conversation and re......MORE |
No adverse social consequences from early ART initiation in West AfricaMichael Carter | 8 years ago Early initiation of antiretroviral therapy (ART) does not have negative social consequences, invest......MORE |
HCV epidemic in North America peaked between 1940 and 1965 with medical procedures likely source of most infectionsMichael Carter | 8 years ago The spread of hepatitis C virus (HCV) in North America peaked between 1940 and 1965, according to r......MORE |
African women in London with poor adherence feel that HIV treatment is difficult and unrelentingRoger Pebody | 8 years ago A qualitative study with West African women living in London who have difficulties adhering to thei......MORE |
Long-acting oral antiretroviral MK-8591 could represent 'paradigm shift' in HIV treatment and prophylaxisMichael Carter | 8 years ago An investigational antiretroviral agent that maintains drug levels that are able to inhibit HIV up ......MORE |
Antidepressant modestly improves HIV-related cognitive impairmentLiz Highleyman | 8 years ago The SSRI antidepressant paroxetine (Paxil) was associated with modest improvement in cognitive func......MORE |
Gene therapy snips HIV out of infected cells and makes uninfected cells resistantGus Cairns | 8 years ago For the first time, researchers have used a gene-editing technique already used to produce cells re......MORE |
Gene therapy snips HIV out of infected cells and makes uninfected cells resistantGus Cairns | 8 years ago For the first time, researchers have used a gene-editing technique already used to produce cells re......MORE |
High-risk anal HPV infections persist in a significant proportion of HIV-negative MSMMichael Carter | 8 years ago Anal infection with human papillomavirus (HPV) types associated with a high risk of pre-cancerous a......MORE |
Isoniazid alone prevents tuberculosis in people with advanced HIV, urine test may lower mortalityLiz Highleyman | 8 years ago Using isoniazid alone to prevent the development of active tuberculosis (TB) in people with advance......MORE |
Tailored programmes encourage black gay men to start and stay on PrEP in US studyLiz Highleyman | 8 years ago Providing culturally tailored support programmes for black men who have sex with men can increase t......MORE |
England’s PrEP policy in disarray after NHS U-turnRoger Pebody | 8 years ago Activists, individuals at risk of HIV, and clinicians have reacted with anger to an official U-turn......MORE |
Opt-out HIV/HBV/HCV testing for patients attending emergency departments identifies significant number of new infectionsMichael Carter | 8 years ago A pilot study involving nine UK emergency departments has shown that routine, opt-out testing for H......MORE |
ART has averted over 850,000 HIV-related opportunistic infections in low and middle income countriesMichael Carter | 8 years ago Rollout of antiretroviral therapy (ART) in low and middle income countries has averted over 850,000......MORE |
Combination inhibitor BMS-986197 demonstrates good activity against HIV in early studyLiz Highleyman | 8 years ago A long-acting bio-engineered molecule with a triple mechanism of action demonstrated potent antivir......MORE |
Starting HIV therapy associated with improvements in liver function, especially when viral load is suppressedMichael Carter | 8 years ago Starting antiretroviral therapy is associated with improvements in liver function in HIV-positive m......MORE |
High sexually transmitted infection rates among men on PrEP supports more frequent monitoringLiz Highleyman | 8 years ago Participants taking tenofovir/emtricitabine (Truvada) for pre-exposure prophylaxis (PrEP) continued......MORE |
HIV-related factors increase risk of strokeTheo Smart | 8 years ago HIV-related risk factors seem to increase the risk of stroke – the sudden death of brain cells du......MORE |
Sofosbuvir/velpatasvir for hepatitis C can be administered with most antiretroviralsLiz Highleyman | 8 years ago Sofosbuvir/velpatasvir, a forthcoming combination that effectively treats all hepatitis C virus (HC......MORE |
Transgender people are at high risk for HIV, but too little is known about prevention and treatment for this populationLiz Highleyman | 8 years ago Transgender women have among the highest rates of HIV infection but little is known about HIV preva......MORE |
Rapid rise in PrEP awareness in US gay men, but only 5% have used PrEPRoger Pebody | 8 years ago Large internet surveys of American gay men show that the proportion who have heard of pre-exposure ......MORE |
Indiana HIV epidemic among people who inject drugs is controlled, but ongoing vigilance is neededLiz Highleyman | 8 years ago Extensive epidemiological investigation followed by prevention and treatment interventions have lar......MORE |
Ravidasvir plus sofosbuvir demonstrates high cure rate for people with hepatitis C genotype 4Liz Highleyman | 8 years ago Sofosbuvir plus the investigational HCV NS5A inhibitor ravidasvir, with or without ribavirin, cured......MORE |
START study shows that people starting HIV treatment earlier have better quality of lifeRoger Pebody | 8 years ago Rather than treatment side-effects having a negative impact on people’s quality of life when they......MORE |
South Africa’s XDR-TB epidemic is due to transmission rather than evolution of resistant strainsTheo Smart | 8 years ago A study in KwaZulu-Natal, South Africa, evaluating the social networks as well as clinical and geno......MORE |
Maraviroc may work as PrEP in combination with another drug – but probably not by itselfGus Cairns | 8 years ago Two studies presented at the Conference on Retroviruses and Opportunistic Infections (CROI 2016) ou......MORE |
Expanding treatment and PrEP could prevent 185,000 new HIV infections, US CDC saysLiz Highleyman | 8 years ago Increasing diagnosis, care and treatment of people living with HIV could lead to a large decrease i......MORE |
Modest kidney function decline in people taking Truvada for PrEP supports need for monitoringLiz Highleyman | 8 years ago Participants taking tenofovir/emtricitabine (Truvada) for pre-exposure prophylaxis (PrEP) in two ma......MORE |
Rate of entry into HIV care improved by personalised counsellingKeith Alcorn | 8 years ago Entry into HIV care can be increased by around 40% if people receive a point-of-care CD4 test and c......MORE |
Studies probe retention in HIV care for women who start antiretroviral treatment during pregnancyCarole Leach-Lemens | 8 years ago Engaging lay counsellors to provide a combination package of evidence-based interventions in Nyanza......MORE |
Experimental TLR7 agonist suppresses HIV-like virus in monkeys after ART interruptionLiz Highleyman | 8 years ago GS-9620, an investigational toll-like receptor or TLR7 agonist, led to immune activation in a stud......MORE |
Study does not support routine HPV quadrivalent vaccination to protect against anal cancer in older people living with HIVKeith Alcorn | 8 years ago The quadrivalent HPV vaccine Gardasil does not protect older adults with HIV against persistent ana......MORE |
‘On-demand’ rectal microbicide gel has reasonable tolerability and acceptability – daily less soGus Cairns | 8 years ago Results from the MTN-017 study of 1% tenofovir gel as a rectal microbicide were presented to the CR......MORE |
Life expectancy in HIV positive people in the US still lags 13 years behind HIV negative peopleGus Cairns | 8 years ago A study presented at the CROI 2016 conference comparing life expectancies of HIV-positive and HIV-n......MORE |
Life expectancy in HIV-positive people in the US still lags 13 years behind HIV-negative peopleGus Cairns | 8 years ago A study presented at the Conference on Retroviruses and Opportunistic Infections (CROI 2016) compar......MORE |
Option B+ has enabled Malawi to make significant progress towards 90-90-90Roger Pebody | 8 years ago In four years Malawi’s treatment cascade for pregnant women has been transformed so that the prop......MORE |
Condom use in French PrEP trial: half only used PrEP, a quarter used condoms and PrEP, one in six used neitherGus Cairns | 8 years ago An analysis of condom use in the placebo-controlled phase of the French IPERGAY trial of intermitte......MORE |
Empirical TB treatment comes up short againTheo Smart | 8 years ago A South African trial has found that a strategy allowing primary care nurses to quickly provide emp......MORE |
Sofosbuvir/ledipasvir for 6 weeks cures HCV in HIV-positive people with acute HCV if viral load is lowLiz Highleyman | 8 years ago An interferon- and ribavirin-free regimen of sofosbuvir/ledipasvir (Harvoni) taken for just 6 weeks......MORE |
Large-scale household TB screening shows feasibility in PopART trialKeith Alcorn | 8 years ago Offering TB screening as part of a home-based HIV testing intervention has the potential to identif......MORE |
Almost-certain case of PrEP failure due to drug resistance reported at CROI 2016Gus Cairns | 8 years ago A case report of a man in Toronto who became infected with a multi-drug-resistant strain of HIV des......MORE |
Almost-certain case of PrEP failure due to drug resistance reported at CROI conferenceGus Cairns | 8 years ago A case report of a man in Toronto who became infected with a multi-drug-resistant strain of HIV des......MORE |
Early antiretroviral therapy reduces the risk of infection-related cancersKeith Alcorn | 8 years ago People who started antiretroviral therapy at a CD4 cell count above 500 had a significantly lower ......MORE |
HIV in the brain: new tools and treatment to keep your mind beautifulTheo Smart | 8 years ago In the future, HIV-associated neurocognitive disorder (HAND) may become less common because of the ......MORE |
Removing clinic barriers to rapid initiation of ART in Uganda enables 70% to start on the same dayRoger Pebody | 8 years ago Making point-of-care CD4 count diagnostics available, revising adherence counselling requirements a......MORE |
Dolutegravir safe and highly effective in older childrenCarole Leach-Lemens | 8 years ago Dolutegravir (DTG) plus optimised background regimen (OBR) is safe, well tolerated and provides vir......MORE |
Long-acting PrEP injection tolerable and acceptable for male volunteers, but dose adjustment neededGus Cairns | 8 years ago The Conference on Retroviruses and Opportunistic Infections (CROI 2016) heard results yesterday fro......MORE |
Tenofovir alafenamide PrEP protects monkeys from infection, but rectal and vaginal levels in humans may be too lowLiz Highleyman | 8 years ago A proof-of-concept study showed that the new tenofovir alafenamide (TAF) plus emtricitabine (FTC, E......MORE |
TAF/emtricitabine maintains viral suppression as well as TDF regimens with less bone and kidney toxicityLiz Highleyman | 8 years ago A fixed-dose coformulation of tenofovir alafenamide (TAF) and emtricitabine (FTC, Emtriva), combine......MORE |
PopART trial shows feasibility of reaching 90-90-90 targets for testing and treatment coverage in Zambia and South AfricaKeith Alcorn | 8 years ago Early findings from the PopART study of the impact of a test-and-treat strategy on antiretroviral t......MORE |
Botswana close to reaching the 90-90-90 testing and treatment targetsKeith Alcorn | 8 years ago Botswana is already close to reaching the 90-90-90 target for testing, treatment and viral suppres......MORE |
Cotrimoxazole prophylaxis provides no benefit for HIV-exposed uninfected childrenCarole Leach-Lemens | 8 years ago Challenging current guidelines, prolonged use of cotrimoxazole (CTX) may not be necessary for HIV-e......MORE |
Partner notification feasible and effective in African settingsRoger Pebody | 8 years ago Partner notification programmes, offering HIV testing to the sexual partners of people newly diagno......MORE |
Very high levels of chemsex and ‘slamsex’ seen in HIV-positive men attending English/Welsh HIV clinicsGus Cairns | 8 years ago A survey of HIV-positive patients attending 30 HIV clinics in England and Wales, presented at the C......MORE |
Option B+ cuts mother-to-child HIV transmission dramatically in MalawiCarole Leach-Lemens | 8 years ago Among women on antiretroviral therapy (ART) prior to pregnancy, early mother-to-child transmission ......MORE |
Starting HIV treatment at first clinic visit improves outcomes in African studyLiz Highleyman | 8 years ago A programme to accelerate the process of HIV diagnosis, preparation and starting antiretroviral the......MORE |
Major disparities persist in lifetime risk of HIV diagnosis in the USLiz Highleyman | 8 years ago The lifetime risk of being diagnosed with HIV in the US has decreased overall during the past decad......MORE |
During pregnancy, offering HIV testing at home doubles the proportion of male partners who testRoger Pebody | 8 years ago A programme of home visits, partner education and HIV testing for couples in Kenya was able to doub......MORE |
People with HIV considerably overestimate their chance of infecting someoneGus Cairns | 8 years ago Only a small proportion of HIV-positive people in a large US treatment study, ACTG A5257, regarded ......MORE |
Bone density recovers quickly after stopping PREPKeith Alcorn | 8 years ago Bone mineral density recovers within six months of stopping pre-exposure prophylaxis (PrEP) contain......MORE |
Dose-finding trials of antibody-based drugs for HIV prevention will start soonGus Cairns | 8 years ago The next generation of pre-exposure prophylaxis (PrEP), and even of HIV treatment, may consist of a......MORE |
Long-acting injectable cabotegravir + rilpivirine works well as HIV maintenance therapyLiz Highleyman | 8 years ago A combination of two long-acting injectable antiretrovirals, cabotegravir and rilpivirine, given on......MORE |
Early antiretroviral therapy has no impact on marker of early cardiovascular diseaseKeith Alcorn | 8 years ago Starting treatment at a CD4 cell count above 500 does not lead to improvement in an important early......MORE |
Women and African-Americans with HIV have a higher risk of strokeKeith Alcorn | 8 years ago The risk of stroke among people living with HIV is highest among people with unsuppressed viral loa......MORE |
Tenofovir treatment raises the risk of broken bonesKeith Alcorn | 8 years ago Treatment containing tenofovir is associated with a higher risk of bone fractures in people living ......MORE |
Vaginal rings containing antiretroviral moderately effective in preventing HIV – but not in the youngest womenGus Cairns | 8 years ago The results of two studies announced today at the annual Conference on Retroviruses and Opportunist......MORE |
Survey shows more than 800,000 people in US have hepatitis B, half of them AsianLiz Highleyman | 8 years ago Although nearly 70 million people in the US have been vaccinated against hepatitis B virus (HBV), t......MORE |
Direct-acting antivirals reduce cryoglobulinemia in hepatitis CKeith Alcorn | 8 years ago Treatment with direct-acting antivirals not only cures people of hepatitis C, but can also rapidly ......MORE |
What do women want from a vaginal microbicide ring?Gus Cairns | 8 years ago In order to maximise confidence in its effectiveness, a vaginal microbicide ring for women would id......MORE |
Telephone intervention can boost retention in care for HIV-positive patients with mental health and drug/alcohol problemsMichael Carter | 8 years ago Retention in HIV care among patients with mental health and/or drug and alcohol problems can be imp......MORE |
PrEP use rising among high-risk gay men in Washington StateLiz Highleyman | 8 years ago More than 20% of gay and bisexual men in Washington State considered to be at high risk for HIV in......MORE |
HIV-infected vaginal cells do not transmit HIV if plasma viral load is undetectable, researchers findGus Cairns | 8 years ago A group of researchers, in experiments on mice, have cleared up an important question about HIV tra......MORE |
Survival and outcome analysis shows that selected HIV-positive patients are good candidates for liver and kidney transplantMichael Carter | 8 years ago Liver and kidney transplant can be justified for carefully selected HIV-positive patients, research......MORE |
Moderate alcohol consumption may be more harmful to people with HIVKeith Alcorn | 8 years ago Safe drinking limits for people living with HIV may be lower than the recommendations for the rest ......MORE |
Neurosyphilis present in 90% of HIV-positive patients with early syphilis in WarsawMichael Carter | 8 years ago The overwhelming majority of early syphilis cases in patients with HIV in Warsaw had neurological i......MORE |
African Americans have highest HIV incidence, lowest rate of consistent careLiz Highleyman | 8 years ago African Americans in the US have the highest rate of new HIV infections, but black people living w......MORE |
Women under-represented in HIV clinical trialsRoger Pebody | 8 years ago Less than a quarter of people taking part in clinical trials for antiretroviral medications are wom......MORE |
Combination nanotherapy drastically reduces the amount of HIV produced by cells in miceGus Cairns | 8 years ago A combination of fine-particle formulations of the drugs atazanavir and ritonavir, plus an immune-d......MORE |
Combination nanotherapy drastically reduces the amount of HIV inside cells in miceGus Cairns | 8 years ago A combination of fine-particle formulations of the drugs atazanavir and ritonavir, plus an immune-d......MORE |
Bladder cancer occurring earlier in people with HIV, and cases more difficult to treat, French study findsMichael Carter | 8 years ago The frequency of bladder cancer is elevated in patients with HIV, investigators from Paris report i......MORE |
Opt-out approach can boost HIV testing ratesRoger Pebody | 8 years ago A large randomised study in an emergency department in San Francisco clearly shows that an ‘opt-o......MORE |
Broad range of risk factors associated with mild cognitive impairment in HIV-positive men on ARTMichael Carter | 8 years ago A broad range of factors are associated with cognitive impairment in middle-aged HIV-positive men, ......MORE |
Tenofovir resistance may develop after HIV treatment failure in over half in sub-Saharan AfricaKeith Alcorn | 8 years ago More than half of people who experienced failure of a tenofovir-based antiretroviral regimen in sub......MORE |
Tenofovir resistance may develop in more than half of patients failing treatment in sub-Saharan AfricaKeith Alcorn | 8 years ago More than half of people who experienced failure of a tenofovir-based antiretroviral regimen in sub......MORE |
New Merck combination pill Zepatier approved for hepatitis C treatment in the United StatesKeith Alcorn | 8 years ago Merck has received a US license for its direct-acting antiviral combination of grazoprevir and elba......MORE |
Criminal laws on HIV transmission make little difference to sexual behaviour – or may make condomless sex more likelyRoger Pebody | 8 years ago A study comparing the sexual behaviour of American gay men living in states with or without laws th......MORE |
London sexual health clinics step up their support for people buying PrEP onlineRoger Pebody | 8 years ago Several large sexual health clinics in London and Brighton have responded to the growing numbers of......MORE |
US study shows importance of access to chemotherapy for HIV-positive patients with Hodgkin lymphomaMichael Carter | 8 years ago HIV is associated with poorer outcomes in patients diagnosed with Hodgkin lymphoma, according to US......MORE |
People taking a large number of non-HIV-related medications more likely to stop or change HIV drugsMichael Carter | 8 years ago HIV-positive patients who are taking a large number of medications for the treatment of non-HIV-rel......MORE |
New PrEP studies will be a challenge, statisticians warnGus Cairns | 8 years ago Two statisticians involved in the PROUD and iPrEx trials of pre-exposure prophylaxis (PrEP) warn th......MORE |
Model suggests HIV vaccine still has key role in ending AIDSLiz Highleyman | 8 years ago Even a modestly effective HIV vaccine would likely be cost-effective and could make a major contri......MORE |
Cardiovascular disease risk is higher for people with hepatitis CKeith Alcorn | 8 years ago People with hepatitis C are at higher risk of dying from cardiovascular disease suffering a stroke ......MORE |
D:A:D study: long-term treatment with tenofovir associated with increased risk of serious liver diseaseMichael Carter | 8 years ago Long-term therapy with the antiretroviral drug tenofovir increases the risk of end-stage liver dise......MORE |
Electrocautery ablation only partially effective as a treatment for high-grade pre-cancerous anal lesions in HIV-positive gay menMichael Carter | 8 years ago Electrocautery ablation is only partially effective as a treatment for high-grade pre-cancerous ana......MORE |
High rates of cervical disease and low rates of screening among women with HIV in DenmarkMichael Carter | 8 years ago Women with HIV have a higher incidence of cervical dysplasia – pre-cancerous cell changes – com......MORE |
Efavirenz-based treatment is safe and effective for young children with HIV exposed to nevirapine for PMTCTMichael Carter | 8 years ago Efavirenz-based treatment is a safe and effective treatment option for children living with HIV pre......MORE |
PrEP, plus increased testing and treatment, could prevent nearly half of HIV infections in gay men in the UK by 2020Gus Cairns | 8 years ago A new British mathematical modelling study published in The Lancet HIV has found that adding pre-e......MORE |
High rates of modifiable cancer risk factors present in Western HIV-positive patientsMichael Carter | 8 years ago The prevalence of potentially modifiable risk factors for some cancers is “extraordinarily high......MORE |
High prevalence of anal infection with high-risk HPV types among HIV-positive women in FranceMichael Carter | 8 years ago A large proportion of women living with HIV in a national study have an anal infection with types o......MORE |
Two cases of PrEP failure on solo tenofovir pose significant research questionsGus Cairns | 8 years ago A report originally presented to the 2015 BHIVA conference last year details two cases where therap......MORE |
MDR-TB treatment: Six drugs better than fiveKeith Alcorn | 8 years ago A regimen containing six drugs was more likely to cure multi-drug resistant tuberculosis (MDR-TB) t......MORE |
Middle-aged people living with HIV have an increased risk of frailtyMichael Carter | 8 years ago Middle-aged people living with HIV have an increased risk of frailty compared with their peers with......MORE |
Not having enough food linked with lower chances of sustained viral suppression for ART-treated breastfeeding mothers in UgandaMichael Carter | 8 years ago Not having enough food is associated with poorer chances of achieving a sustained viral suppression......MORE |
Hepatitis C virus linked to increased risk of Parkinson's disease, studies showLiz Highleyman | 8 years ago People with hepatitis C virus (HCV) infection may be more likely to develop Parkinson's disease, e......MORE |
HIV-positive patients lost to follow-up successfully identified and re-engaged with care by programme in LA CountyMichael Carter | 8 years ago A programme in Los Angeles County successfully re-engaged and retained patients who dropped out of ......MORE |
LAM point-of-care TB testing reduces mortality in people with HIV/TB co-infection in hospitalLesley Odendal | 8 years ago All-cause 8-week mortality is reduced by rapid point-of-care urine-based testing for tuberculosis (......MORE |
Annual testing and scale-up of PrEP could slow the Dutch gay HIV epidemicRoger Pebody | 8 years ago Phylogenetic analysis of the source of HIV infections in Dutch gay men over more than a decade show......MORE |
Xpert MTB/RIF testing has reduced MDR-TB treatment delays in South AfricaLesley Odendal | 8 years ago Although the introduction of the Xpert MTB/RIF test for TB and drug-resistant TB has improved the ......MORE |
Lessons learnt from the history of contraception are relevant for the implementation of PrEPRoger Pebody | 8 years ago Achieving a widespread and appropriate use of pre-exposure prophylaxis (PrEP) will take several yea......MORE |
One in eight children with confirmed TB have drug-resistant TB in Cape TownLesley Odendal | 8 years ago One in eight children with confirmed TB have drug-resistant TB in Cape Town, South Africa, accordin......MORE |
Malawian study provides strong evidence that HIV infection is an important risk factor for strokeMichael Carter | 8 years ago HIV infection is an important risk factor for stroke among adults in Malawi, investigators report i......MORE |
HIV salvage regimens can safely omit NRTIs, says US studyMichael Carter | 8 years ago Nucleoside reverse transcriptase inhibitors (NRTIs) can be safely omitted from HIV salvage therapy,......MORE |
DAAs could halt HCV epidemic in US – but only with near-universal testing and big increase in treatment ratesMichael Carter | 8 years ago Treatment using direct-acting agents (DAA) could have a major impact on the hepatitis C virus (HCV)......MORE |
A quarter of people with HCV initially refused access to sofosbuvir/lepidasvir, says US study, but most successfully appealMichael Carter | 8 years ago Insurers deny almost a quarter of requests for sofosbuvir/lepidasvir (Harvoni) to treat people with......MORE |
Community care workers boost TB case finding among hard-to-reach adultsLesley Odendal | 8 years ago Community care worker active case finding is an effective tool for increasing TB case detection, ac......MORE |
Previous AIDS-related pulmonary disease associated with lung cancer risk for people with HIVMichael Carter | 8 years ago AIDS-related pulmonary disease is a major factor in the increased risk of lung cancer seen in peopl......MORE |
Low implementation of Xpert MTB/RIF among HIV/TB co-infected adults in 19 low- and middle-income countriesLesley Odendal | 8 years ago Three quarters of people with HIV/TB co-infection did not receive Xpert MTB/RIF testing for TB diag......MORE |
Large UK study shows low rates of HIV testing, even among those who think they are at risk of HIVRoger Pebody | 8 years ago A major household survey of adults in the UK shows that, even among people who perceive themselves ......MORE |
Evidence for PrEP efficacy grows, but implementation presents challengesLiz Highleyman | 8 years ago Pre-exposure prophylaxis (PrEP) was a major topic at the 2015 National HIV Prevention Conference (N......MORE |
Tenofovir alafenamide fumarate at what price? No more than $1000 a year above existing tenofovir formulation, says modelMichael Carter | 8 years ago The superior safety of the tenofovir analogue tenofovir alafenamide fumarate (TAF) over tenofovir d......MORE |
Two-drug ART with dolutegravir-lamivudine would be cost-effective and achieve substantial cash savingsMichael Carter | 8 years ago Virologically suppressive first-line antiretroviral treatment with a two-drug regimen of dolutegrav......MORE |
US syringe funding ban impedes HIV and hepatitis C preventionLiz Highleyman | 8 years ago Providing sterile syringes is a proven effective way to prevent HIV and hepatitis C virus (HCV) inf......MORE |
UK maintains the largest HIV epidemic in western Europe...Gus Cairns | 8 years ago The annual surveillance report released recently by the European Centre for Disease Prevention and ......MORE |
UK maintains the largest HIV epidemic in western EuropeGus Cairns | 8 years ago The annual surveillance report released recently by the European Centre for Disease Prevention and ......MORE |
Sofosbuvir/daclatasvir combination could be produced for $200 per hepatitis C cureKeith Alcorn | 8 years ago Month-by-month tracking of the prices paid in India for the chemicals used to make hepatitis C dire......MORE |
Sofosbuvir / daclatasvir combination could be produced for $200 per hepatitis C cureKeith Alcorn | 8 years ago Month-by-month tracking of the prices paid in India for the chemicals used to make hepatitis C dire......MORE |
Drug resistance acquired during HIV PrEP rapidly disappears after medication is discontinuedMichael Carter | 8 years ago Drug resistance acquired in rare cases of HIV infection during treatment with pre-exposure prophyla......MORE |
Grazoprevir/elbasvir cures more than 90% of people with HIV/HCV co-infectionLiz Highleyman | 8 years ago Merck's grazoprevir/elbasvir combination cured 93% of people with HIV and hepatitis C co-infection,......MORE |
Death during MDR-TB treatment more likely in people with HIV and underweight or most drug-resistant patientsKeith Alcorn | 8 years ago People living with HIV, those who are underweight and those with more extensive drug resistance are......MORE |
National HIV Prevention Conference highlights progress and disparitiesLiz Highleyman | 8 years ago Pre-exposure prophylaxis (PrEP), integration of prevention and treatment services, and initiatives ......MORE |
United States faces biggest burden of hepatitis C treatment costs before 2020Keith Alcorn | 8 years ago The cost of treating hepatitis C is likely to decline dramatically over the next decade in the Unit......MORE |
New HIV cases decline in US, but population and geographic disparities persistLiz Highleyman | 8 years ago HIV diagnoses have declined by nearly 20% overall during the past decade but progress has been une......MORE |
9-month MDR-TB regimen cures 82% in African studyKeith Alcorn | 8 years ago A nine-month standardised treatment regimen for multi-drug resistant tuberculosis (MDR-TB) cured 82......MORE |
San Francisco reports progress in 'Getting to Zero' HIV prevention and treatment effortLiz Highleyman | 8 years ago San Francisco made good progress in HIV prevention and treatment during 2015, and its successes ha......MORE |
San Francisco reports progress in 'Getting to Zero' HIV prevention and treatment effortKeith Alcorn | 8 years ago San Francisco made good progress in HIV prevention and treatment during 2015, and its successes ha......MORE |
Coffee consumption linked to reduced liver fibrosis in people with HBV, HCV and NAFLDLiz Highleyman | 8 years ago Drinking coffee was associated with lower liver stiffness – a non-invasive measure used to estima......MORE |
Gay men starting to use crystal meth usually increase their sexual risk takingRoger Pebody | 8 years ago A study which followed the same group of gay men over several years has found that individuals who ......MORE |
Australian survey finds that less than a third of gay men have committed relationships with just one partnerGus Cairns | 8 years ago A large survey conducted through gay dating sites and Facebook in Australia has found that previous......MORE |
Ipergay PrEP study results publishedGus Cairns | 8 years ago The results from the Ipergay study of intermittent pre-exposure prophylaxis (PrEP) were published i......MORE |
WHO issues recommendations on linkage to care, retention, to help bring HIV treatment to allKeith Alcorn | 8 years ago The World Health Organization has issued new recommendations on how to organise services in order t......MORE |
Many more people could benefit from HIV PrEP but not enough doctors are aware, says CDCLiz Highleyman | 8 years ago One-quarter of gay and bisexual men in the US and one-fifth of people who inject drugs -- but less......MORE |
For African migrants in Europe, destitution shapes sexual behaviour and HIV riskRoger Pebody | 8 years ago For African migrants recently arrived in France, periods without a residence permit, secure housing......MORE |
Two-drug maintenance therapy keeps viral load suppressed and may even have advantages over traditional ARTMichael Carter | 8 years ago Two-drug antiretroviral therapy (ART) consisting of ritonavir-boosted atazanavir and lamivudine has......MORE |
High HCV cure rate demonstrated for people retreated after failure of short course direct-acting antiviral therapyLiz Highleyman | 8 years ago People with hepatitis C who did not achieve sustained virological response with a prior short cours......MORE |
HIV-related wasting can have long-term consequencesMichael Carter | 8 years ago HIV-associated wasting can have a long-term impact on physical function and quality of life, accord......MORE |
Dutch research identifies relationship between HIV clinic characteristics and retention of patients in careMichael Carter | 8 years ago Dutch research published in the online edition of AIDS has provided insights into the relationship ......MORE |
Triple DAA regimen cures hepatitis C patients with rapid response in just 3 weeksLiz Highleyman | 8 years ago Response-guided therapy using an all-oral regimen of three direct-acting antivirals cured a majori......MORE |
Clinical impact of effective HCV DAAs: referrals for liver transplant drop after their introductionMichael Carter | 8 years ago The number of hepatitis C virus (HCV)-related referrals for liver transplant has declined significa......MORE |
France approves PrEPGus Cairns | 8 years ago In a historic move, France has become the first country outside the USA, and the first country with......MORE |
Study reveals potential challenges for scaling up of HCV therapy in UKMichael Carter | 8 years ago A large proportion of patients with chronic hepatitis C virus (HCV) infection in the UK have co-mor......MORE |
Liver fibrosis improves after successful treatment for hepatitis CLiz Highleyman | 8 years ago A majority of people with chronic hepatitis C and advanced fibrosis or cirrhosis showed improvement......MORE |
Widely-used anti-alcoholism drug wakes up dormant HIV-infected cellsGus Cairns | 8 years ago An Australian research team has found that disulfiram, a long-established and safe drug used primar......MORE |
Daclatasvir and sofosbuvir with ribavirin cures 90% of people with genotype 3 hepatitis CLiz Highleyman | 8 years ago An all-oral combination of daclatasvir, sofosbuvir and ribavirin taken for 12 or 16 weeks led to hi......MORE |
Daclatasvir plus sofosbuvir works well for people with genotype 3 hepatitis C and advanced liver disease in real-world clinical practiceLiz Highleyman | 8 years ago Interferon-free treatment with daclatasvir plus sofosbuvir, with or without ribavirin, led to susta......MORE |
Tenofovir during pregnancy reduces risk of mother-to-child hepatitis B virus transmissionLiz Highleyman | 8 years ago Women with chronic hepatitis B and high viral load who were treated with tenofovir (Viread) during ......MORE |
UK’s latest HIV figures show the need to scale up HIV testing and preventionRoger Pebody | 8 years ago The latest annual report by Public Health England shows that, although the number of gay men who ha......MORE |
New AbbVie hepatitis C combination cures 93%-97% with genotype 3Keith Alcorn | 8 years ago A combination of two experimental direct-acting antivirals developed by AbbVie cured 93%-97% of peo......MORE |
Sofosbuvir/ledipasvir plus vedroprevir shows 96% response rate for hard-to-treat genotype 1 hepatitis C patientsLiz Highleyman | 8 years ago A triple combination of Gilead Sciences' sofosbuvir/ledipasvir (Harvoni) plus the experimental HCV......MORE |
Barcelona clinic study counts how many gay men might benefit from PrEPGus Cairns | 8 years ago A study from the Barcelona Checkpoint gay men’s HIV clinic, presented at the recent 15th European......MORE |
Sofosbuvir/velpatasvir shows high cure rates for all HCV genotypes, works well for patients with liver decompensationLiz Highleyman | 8 years ago A coformulation of sofosbuvir and the pan-genotypic HCV NS5A inhibitor velpatasvir from Gilead Scie......MORE |
Sofosbuvir & ravidasvir delivers high sustained response rates for genotype 4 hepatitis C patientsLiz Highleyman | 8 years ago A regimen of sofosbuvir and the pan-genotypic HCV NS5A inhibitor ravidasvir, with or without ribavi......MORE |
Treatment intensification with sofosbuvir permits cure after failure of previous HCV treatmentKeith Alcorn | 8 years ago Re-treating with an interferon-free regimen that previously failed to cure hepatitis C can result i......MORE |
Almost half of US Medicaid recipients denied funding for hepatitis C treatment, 4-state study showsKeith Alcorn | 8 years ago Around one in six people with hepatitis C in four US states had their prescriptions for direct-acti......MORE |
New AbbVie hepatitis C pan-genotypic combination cures 97% - 100% in early studyKeith Alcorn | 8 years ago A combination of two experimental direct-acting antivirals developed by AbbVie cured 97%-100% of no......MORE |
REP 2139 shows promise for people with hepatitis B and hepatitis delta co-infectionLiz Highleyman | 8 years ago The nucleic acid-based polymer REP 2139, used first as monotherapy then combined with pegylated int......MORE |
Liver cancer risk will remain elevated for people with cirrhosis cured of hepatitis CKeith Alcorn | 8 years ago The burden of liver cancer and cirrhosis caused by hepatitis C is likely to continue to grow in the......MORE |
Sofosbuvir/velpatasvir + GS-9857 for 8 weeks cures hepatitis C for most people with genotype 1 or 3Liz Highleyman | 8 years ago An 8-week triple combination of Gilead Sciences' sofosbuvir, velpatasvir and GS-9857 showed a high ......MORE |
HCV transmission during anal sex may happen without blood, study in HIV/HCV coinfected men findsKeith Alcorn | 8 years ago Hepatitis C virus is present in large enough quantities in the rectal fluid of men with HIV and hep......MORE |
Grazoprevir/elbasvir shows high hepatitis C cure rate for people who inject drugsLiz Highleyman | 8 years ago Merck's grazoprevir/elbasvir coformulation cured hepatitis C infection in 92% of injecting drug us......MORE |
People with HIV and HCV co-infection achieve high HCV cure rates with grazoprevir/elbasvirLiz Highleyman | 8 years ago A dual combination of Merck's grazoprevir and elbasvir taken for 12 or 16 weeks cured most HIV-posi......MORE |
Women living with HIV in the UK continue to have poorer treatment outcomesRoger Pebody | 8 years ago Women have triple the rate of poor treatment outcomes of gay men and the gap has not narrowed over ......MORE |
Ambivalence and tensions in young gay men’s accounts of monogamy and relationshipsRoger Pebody | 8 years ago Young Australian gay men’s feelings about sex and relationships are characterised by a tension be......MORE |
Low CD4 count, smoking and unhealthy alcohol use are risk factors for acute exacerbation of COPD in people with HIVMichael Carter | 8 years ago HIV infection increases the risk of acute exacerbation of chronic obstructive pulmonary disease (AE......MORE |
Truvada PrEP appears to work for transgender women, but only if used consistentlyLiz Highleyman | 8 years ago The more than 300 transgender women in the pivotal iPrEx pre-exposure prophylaxis (PrEP) trial had......MORE |
Counselling for HIV sero-discordant couples associated with reductions in HIV risk behaviourMichael Carter | 8 years ago Counselling for HIV sero-discordant couples can achieve significant reductions in sexual risk behav......MORE |
How do we maximise global HIV treatment access? IAPAC Care Continuum Guidelines make recommendationsGus Cairns | 8 years ago IAPAC, the International Association of Practitioners in AIDS Care, has issued a set of guidelines ......MORE |
Does low-level HIV viral load raise the risk of disease progression and co-morbidities?Liz Highleyman | 8 years ago People living with HIV who have a detectable but low viral load – in the range of 50 to 500 or 10......MORE |
Hormonal contraception safe for women with HIV and may have important health benefitsMichael Carter | 8 years ago HIV-positive women can safely use hormonal contraception, according to research published in the on......MORE |
Patients of non-specialist HIV physicians often have poor ART outcomes and frequently receive sub-optimal careMichael Carter | 8 years ago Physician experience is associated with the quality of care provided to HIV-positive patients, new ......MORE |
Hepatitis C incidence remains stable among gay men living with HIV in Europe, but varies across countriesLiz Highleyman | 8 years ago Researchers have seen no decline in new hepatitis C virus (HCV) infections among HIV-positive men w......MORE |
Post-treatment control of HIV appears rare, biomarkers may help predict viral reboundLiz Highleyman | 8 years ago Only four individuals out of nearly 5000 people receiving care at US military health facilities wer......MORE |
Many HIV transmissions in sero-discordant couples occuring at CD4 cell counts above ART eligibility thresholdMichael Carter | 8 years ago Many HIV transmissions in sero-discordant couples occur when the HIV-infected partner has a high CD......MORE |
Priorities for HIV care: the perspectives of healthcare providers and patientsMichael Carter | 8 years ago Virological suppression and co-morbidities are the main focus of consultations between HIV healthca......MORE |
Sofosbuvir/ledipasvir for 8 weeks cures most hard-to-treat hepatitis C patients in real-world studyLiz Highleyman | 8 years ago Most people with hepatitis C virus (HCV) in the GECCO German hepatitis C cohort who were treated wi......MORE |
Successful hepatitis C treatment lowers risk of death for people with HIV and HCV co-infectionLiz Highleyman | 8 years ago Hepatitis C treatment that leads to sustained virological response (SVR) – generally regarded as ......MORE |
Strategies for hepatitis C ‘treatment as prevention’ must address the concerns of people who inject drugsRoger Pebody | 8 years ago While epidemiologists and public health experts are excited by the potential of new hepatitis C dru......MORE |
HIV maturation inhibitor BMS-955176 shows good safety and efficacy in phase 2a trialLiz Highleyman | 8 years ago Bristol-Myers Squibb’s next-generation maturation inhibitor BMS-955176 demonstrated good antivira......MORE |
START sub-studies show no differences in lung or neurocognitive function with early or later treatmentLiz Highleyman | 8 years ago Participants who started antiretroviral therapy (ART) soon after HIV diagnosis in the large START ......MORE |
Community-based drug projects provide an alternative to compulsory detention in AsiaRoger Pebody | 8 years ago A series of pilot projects in China, Indonesia and Cambodia are showing that non-coercive, communit......MORE |
START sub-study shows more bone loss with earlier HIV treatmentLiz Highleyman | 8 years ago Participants who started antiretroviral therapy (ART) soon after HIV diagnosis in the large START t......MORE |
London clinic survey shows impact of chemsex on condom and PEP useKeith Alcorn | 8 years ago A survey of gay men in London using drugs during sex – chemsex – has shown high levels of unpro......MORE |
Risk of heart attack rises with length of HIV infection, regardless of ageKeith Alcorn | 8 years ago Ten years after becoming infected with HIV, a person living with HIV has approximately twice the ri......MORE |
Harm reduction conference calls for political leadership to reform drugs policyRoger Pebody | 8 years ago The biggest challenges to harm reduction are drugs policy and drugs laws, the Malaysian harm reduct......MORE |
Harm reduction conference calls for political leadership on drugs policy reformRoger Pebody | 8 years ago The biggest challenges to harm reduction are drugs policy and drugs laws, the Malaysian harm reduct......MORE |
With EACS release, all international HIV treatment guidelines agree on when to start – for the first time since 2006Gus Cairns | 8 years ago The new European AIDS Clinical Society (EACS) HIV clinical guidelines, released last week at the 15......MORE |
Tenofovir alafenamide single-tablet regimen shows good efficacy with improved kidney and bone safetyLiz Highleyman | 8 years ago A single-tablet regimen containing the new tenofovir alafenamide (TAF) - to be marketed as Genvoya......MORE |
When will Europe get PrEP?Keith Alcorn | 8 years ago Pressure is mounting at community level for access to pre-exposure prophylaxis (PrEP) in Europe and......MORE |
Can dolutegravir dual therapy or monotherapy produce and maintain HIV suppression?Liz Highleyman | 8 years ago The potent integrase inhibitor dolutegravir taken with a single well-tolerated NRTI was able to ful......MORE |
The majority of migrants living with HIV in Europe may have acquired HIV in their new countryGus Cairns | 8 years ago A study presented at the 15th European AIDS Conference yesterday found evidence that the majority o......MORE |
Benefits of early HIV treatment are clear, but issues raised by START and D:A:D remain unresolvedLiz Highleyman | 8 years ago The long-running controversy over when to start antiretroviral therapy (ART) has been definitively ......MORE |
Needle and syringe exchanges need to adapt to meet the needs of people who inject steroids and image-enhancing drugsRoger Pebody | 8 years ago The numbers of people injecting steroids and other image-enhancing drugs has increased significantl......MORE |
Newest MDR-TB drug prices could fall by up to 95% through generic productionKeith Alcorn | 8 years ago The cost of newer drugs for the treatment of multidrug-resistant tuberculosis (MDR-TB) could be cut......MORE |
TB death rate four times higher in Eastern Europe due to lack of HIV treatment after TB diagnosisKeith Alcorn | 8 years ago People living with HIV in Eastern Europe who develop tuberculosis (TB) are four times more likely t......MORE |
Three-month isoniazid/pyrazinamide regimen prevents TB as well as 6-month isoniazid in people living with HIVKeith Alcorn | 8 years ago A daily three-month regimen of isoniazid and pyrazinamide is just as effective at preventing the de......MORE |
Can Europe reach the 90-90-90 target for HIV treatment by 2020?Keith Alcorn | 8 years ago The European region needs to step up prevention and treatment activities if it is to reach the UNAI......MORE |
Modest bone loss seen in young men taking Truvada for pre-exposure prophylaxisLiz Highleyman | 8 years ago Young men participating in a pre-exposure prophylaxis (PrEP) demonstration project experienced mode......MORE |
Why is injecting equipment re-used? Drug users do their own research to find outRoger Pebody | 8 years ago Even in the context of the relatively good access to harm reduction services in Australia, the prin......MORE |
Peer workers improve drug users’ engagement with HIV care in UkraineRoger Pebody | 8 years ago An innovative programme in which peer outreach workers use a case management approach to help HIV-p......MORE |
One third of people with HIV in US study are not virally suppressed on antiretroviral therapyLiz Highleyman | 8 years ago A third of people with HIV on antiretroviral therapy (ART) do not have sustained viral suppression ......MORE |
How do we treat the world? Experts discuss moving to universal HIV treatmentGus Cairns | 8 years ago What practical steps does the global healthcare community need to take in order to expand HIV treat......MORE |
Sofosbuvir + daclatasvir demonstrates high cure rates for people with HIV and HCV co-infectionLiz Highleyman | 8 years ago Nearly all people with HIV and genotype 1-4 HCV co-infection treated for 12 weeks with an interfero......MORE |
Retreat of international donors and neglect of national governments threatens harm reduction servicesRoger Pebody | 8 years ago The availability of needle and syringe programmes, opioid substitution therapy and other harm reduc......MORE |
Emergency needle exchange in Indiana reduces HIV and HCV risk for people who inject drugsLiz Highleyman | 8 years ago An emergency syringe exchange program implemented after an outbreak of HIV earlier this year in the......MORE |
US study provides 'real world' evidence about which patients with hepatitis C should be prioritised for therapyMichael Carter | 8 years ago For patients with hepatitis C virus (HCV) mono-infection, baseline fibrosis stage is strongly predi......MORE |
Opioid substitution therapy, especially in combination with needle exchange, reduces transmission of hepatitis CRoger Pebody | 8 years ago A pooled analysis of 25 studies has shown for the first time good evidence that methadone and other......MORE |
Studies continued to support tenofovir alafenamide combination pill as it nears US approvalLiz Highleyman | 8 years ago A single-tablet regimen containing a new formulation of tenofovir maintained viral suppression for ......MORE |
Hepatitis C-related mortality continues to increase in the USLiz Highleyman | 8 years ago Deaths related to hepatitis C virus (HCV) infection continue to rise in the US despite the advent o......MORE |
At least 25,000 people in the US may now be using PrEPGus Cairns | 8 years ago As many as 30,000 people in the US may now be taking pre-exposure prophylaxis to prevent HIV, the f......MORE |
Abacavir/lamivudine could be driving liver damage in ART-treated patients with HIV/HCV co-infectionMichael Carter | 8 years ago Progression of liver fibrosis among ART-treated patients with HIV/HCV co-infection is associated wi......MORE |
HIV attachment inhibitor BMS-663068 matches atazanavir in phase 2b studyLiz Highleyman | 8 years ago Bristol-Myers Squibb’s HIV attachment inhibitor BMS-663068 (fostemsavir), which prevents the viru......MORE |
Interferon-free treatment works well for people who inject drugs, but barriers to access remainLiz Highleyman | 8 years ago Hepatitis C treatment for people who inject drugs, including those receiving opioid substitution th......MORE |
Affordable Care Act coverage improves chances of viral suppression for Americans with HIVLiz Highleyman | 8 years ago Enrolling low-income and under-insured people with HIV in one of the new Affordable Care Act (ACA)......MORE |
No transmission of integrase inhibitor-resistant HIV seen in California patientsGus Cairns | 8 years ago Not one case of transmission of HIV that is resistant to any of the integrase inhibitor (INI) drugs......MORE |
People who inject drugs should have access to hepatitis C treatment, expert panel recommendsKeith Alcorn | 8 years ago New recommendations on hepatitis C treatment and care for people who inject drugs encourage physici......MORE |
People with HIV are at higher risk of several types of cancer, large study findsLiz Highleyman | 8 years ago People living with HIV remain at risk of AIDS-defining cancers in the era of effective antiretrovir......MORE |
New antiretrovirals and HIV treatment strategies highlighted at ICAACLiz Highleyman | 8 years ago Researchers presented findings from several HIV studies at the 55th Interscience Conference on Ant......MORE |
US HIV physicians routinely offering early ART but only a third have prescribed PrEPMichael Carter | 8 years ago Most doctors at the frontline of the HIV epidemic in the United States recommend early antiretrovir......MORE |
Recent infection and ART treatment interruptions are key periods for HIV transmissionMichael Carter | 8 years ago A large proportion of HIV transmissions occur during recent infection or antiretroviral treatment i......MORE |
New HCV NS5A inhibitor EDP-239 looks good in early studies, more evidence supports early hepatitis C treatmentLiz Highleyman | 8 years ago A new hepatitis C virus (HCV) NS5A inhibitor being developed by Enanta – EDP-239 – was well-tol......MORE |
PrEP preferences in gay men are predicted by the frequency and predictability of the sex they haveGus Cairns | 8 years ago A recently-published survey from the US and Canada reveals that on the whole HIV-negative gay men w......MORE |
WHO guidelines recommend universal antiretroviral treatment, PrEP for those at substantial riskLiz Highleyman | 8 years ago The World Health Organization (WHO) released updated guidelines today calling for antiretroviral th......MORE |
The enduring power of stigma – understanding why HIV-positive gay men don’t disclose their statusRoger Pebody | 8 years ago The accounts of a group of gay men living with HIV in Dublin, most of whom rarely, if ever, disclos......MORE |
High standards of care associated with reduced mortality risk of patients with HIVMichael Carter | 8 years ago Quality of care (QOC) in the first twelve months after entering HIV care is associated with longer-......MORE |
High standards of care associated with reduced mortality risk of patients with HIVMichael Carter | 8 years ago Quality of care (QOC) in the first twelve months after entering HIV care is associated with longer-......MORE |
Second UK cost-effectiveness study finds that large PrEP programmes may need drug price cut to be affordableGus Cairns | 8 years ago A second UK cost-effectiveness study of pre-exposure prophylaxis has concluded that a medium-sized ......MORE |
Substantial improvement in life expectancy of older HIV-positive patients in modern treatment era, report DanesMichael Carter | 8 years ago The prognosis of older HIV-positive patients has improved substantially during the era of combinati......MORE |
Increasing levels of engagement with care is key to controlling HIV epidemic in USMichael Carter | 8 years ago “Test-and-treat” is unlikely to be an effective strategy to control the HIV epidemic in the Uni......MORE |
Awareness of treatment’s impact on transmission is transforming the lives of couples of mixed HIV statusRoger Pebody | 8 years ago A greater understanding of the impact of HIV treatment on prevention is changing the experience of ......MORE |
Sexual transmission of HCV is increasing among gay and bisexual men with HIV, meta-analysis findsLiz Highleyman | 8 years ago Sexual transmission of hepatitis C virus (HCV) is occurring among HIV-positive men who have sex wit......MORE |
Thai testing campaign suggests how local cultures can influence testing behaviourGus Cairns | 8 years ago A campaign to encourage Thai gay men and other men who have sex with men (MSM) to test at least onc......MORE |
Spanish pharmacy HIV testing programme detects many new infectionsGus Cairns | 8 years ago A programme in which cheap, 30-minute HIV tests were offered in local pharmacy shops in three Spani......MORE |
Cost of comprehensive global viral hepatitis prevention and treatment effort might peak at $11 billion in 2025Keith Alcorn | 8 years ago Reaching the World Health Organization’s (WHO) proposed targets for viral hepatitis control by 20......MORE |
PROUD PrEP study results publishedGus Cairns | 8 years ago The results of the PROUD study of HIV pre-exposure prophylaxis (PrEP) using daily tenofovir + emtri......MORE |
Bone loss slows, but continues long-term in HIV-positive people on antiretroviral therapyLiz Highleyman | 8 years ago People with HIV experienced a decrease in bone density at the hip and spine during their first two ......MORE |
Asymptomatic neurocognitive impairment in people with HIV does predict later neurocognitive symptomsLiz Highleyman | 8 years ago People with HIV who showed evidence of asymptomatic neurocognitive impairment at study entry were n......MORE |
Rilpivirine + darunavir HIV maintenance regimen matches standard three-drug antiretroviral therapyLiz Highleyman | 8 years ago An NRTI-sparing dual antiretroviral regimen consisting of the NNRTI rilpivirine (Edurant) plus the ......MORE |
US PrEP care cascade analysis suggests that major, structural barriers need to be addressed for PrEP to have an impactRoger Pebody | 8 years ago The uptake of PrEP in people who need it risks being limited due to low levels of awareness, gaps i......MORE |
Medicines Patent Pool looks at hepatitis CKeith Alcorn | 8 years ago Greg Perry, Executive Director of the Medicines Patent Pool, told delegates at the World Hepatitis ......MORE |
Oestrogen may block HIV reactivation, hints at gender differences in viral reservoirsLiz Highleyman | 8 years ago Oestrogen receptors on cells may play a role in HIV latency and reactivation, and drugs targeting t......MORE |
Half of American gay men using dating apps have interacted with a PrEP userRoger Pebody | 8 years ago Almost half of American gay men recruited to a survey via advertising on a major mobile phone datin......MORE |
‘Undetectable’ is both a milestone and an identity for gay men recently diagnosed with HIVRoger Pebody | 8 years ago Achieving an undetectable viral load is a key milestone in the period after diagnosis with HIV, qua......MORE |
World Health Organization calls for ambitious global targets for viral hepatitis controlKeith Alcorn | 8 years ago The World Health Organization (WHO) is calling for ambitious new global targets for diagnosis, trea......MORE |
No HIV infections seen in San Francisco PrEP users referred via primary careGus Cairns | 8 years ago A programme that provides pre-exposure prophylaxis (PrEP) through primary care referrals in San Fra......MORE |
STI clinic attendees have high HIV diagnosis rates in Netherlands, but many missed opportunities in primary careGus Cairns | 8 years ago Two studies from the Netherlands show that while the proportion of people with HIV who are diagnose......MORE |
HIV treatment as prevention scale-up linked to reduced mortality among people who inject drugs in VancouverLiz Highleyman | 8 years ago HIV-related and all-cause death decreased significantly among people who inject drugs – with sim......MORE |
HIV-positive youth are less likely than adults to achieve viral suppression on antiretroviral treatmentLiz Highleyman | 8 years ago While adolescents and young adults are about as likely as older people to be linked to care after b......MORE |
Fatty liver may contribute to higher risk of death for HIV/HCV co-infected peopleLiz Highleyman | 8 years ago About a quarter of people in a New York City cohort who had HIV and hepatitis C virus (HCV) died ov......MORE |
Good outcomes for people living with HIV diagnosed with Hodgkin's lymphoma in FranceMichael Carter | 8 years ago People living with HIV who are diagnosed with Hodgkin’s lymphoma now have excellent outcomes, Fre......MORE |
HCV infection associated with hardening of the coronary arteryMichael Carter | 8 years ago Chronic hepatitis C virus (HCV) infection is associated with an important early warning side of car......MORE |
HIV-treatment 'booster drugs' are most likely to have dangerous interactions with methamphetamine, mephedrone, MDMA and ketamineRoger Pebody | 8 years ago The two drugs involved in HIV treatment that are most likely to have dangerous interactions with re......MORE |
Ugandan gay men talk about why they do not always use condomsGus Cairns | 8 years ago Gay men and other men who have sex with men (MSM) in Uganda, who had not used a condom last time th......MORE |
HIV-positive postpartum women who rapidly re-engage with HIV care more likely to have viral suppression in longer termMichael Carter | 8 years ago HIV-positive women who have recently given birth have low rates of engagement with HIV care, invest......MORE |
Low rates of engagement with HIV care among women who have recently given birth in Cape Town townshipsMichael Carter | 8 years ago Only half of HIV-positive mothers in townships near Cape Town, South Africa, who received antenatal......MORE |
People with HIV and hepatitis B co-infection can safely switch to simpler TAF single-tablet regimenLiz Highleyman | 8 years ago People with HIV and hepatitis B virus (HBV) co-infection maintained HIV viral suppression, maintain......MORE |
Hepatitis C cure associated with significant improvement in liver stiffness in people with HIV and HCV co-infectionMichael Carter | 8 years ago A successful response to hepatitis C virus (HCV) therapy is associated with a significant improveme......MORE |
People with hepatitis B can safely use Truvada PrEP for HIV preventionLiz Highleyman | 8 years ago People with hepatitis B virus (HBV) infection did not experience liver inflammation 'flares' or oth......MORE |
Study sheds light on how tenofovir is processed in different body tissuesLiz Highleyman | 8 years ago Tenofovir, which is widely used for HIV treatment and prevention, is activated in a tissue-specific......MORE |
Third of people with HIV who use drugs intentionally miss doses of HIV treatment when planning to use drugsMichael Carter | 8 years ago Beliefs about possible toxic interactions between antiretroviral therapy (ART) and illicit drugs ar......MORE |
Low-threshold methadone maintenance reduces HIV risk for people who inject drugsKeith Alcorn | 8 years ago Receiving methadone maintenance therapy through primary care physicians or community pharmacies sig......MORE |
First Brazilian PrEP data reinforce evidence that PrEP is most used by those at greatest riskGus Cairns | 8 years ago The first data from a Brazilian open-label demonstration project of HIV pre-exposure prophylaxis (P......MORE |
Cirrhosis and decompensation are common among people with chronic hepatitis CLiz Highleyman | 8 years ago More than one-quarter of people with chronic hepatitis C at Kaiser-Permanente developed liver cirrh......MORE |
Indiana HIV outbreak offers lessons about containing local outbreaks and need for harm reductionLiz Highleyman | 8 years ago An early-2015 outbreak of HIV and hepatitis C virus (HCV) in rural Indiana, USA, linked to injectio......MORE |
Starting ART reduces TB risk for HIV-positive patients in South AfricaMichael Carter | 8 years ago Starting antiretroviral therapy (ART) significantly reduces the risk of tuberculosis (TB) for patie......MORE |
WAVES shows elvitegravir regimen beats boosted atazanavir for women with HIVLiz Highleyman | 8 years ago A study of antiretroviral treatment specifically for women with HIV showed that a single-tablet reg......MORE |
Open-label PrEP in Botswana: very high adherence and no HIV infections seenGus Cairns | 8 years ago A study of open-label Truvada HIV pre-exposure prophylaxis (PrEP) in Botswana among heterosexual pe......MORE |
Peer or community interventions improve outcomes for mothers with HIVCarole Leach-Lemens | 8 years ago Peer- and community-based interventions can significantly increase retention in care of mothers wit......MORE |
Retention in pre-ART care can be boosted by monthly visits from volunteer support workersMichael Carter | 8 years ago Retention in HIV care for patients not eligible for antiretroviral therapy (ART) can be boosted by ......MORE |
Daclatasvir plus sofosbuvir cures HCV for most people with HIV and HCV co-infection in French compassionate use programmeLiz Highleyman | 8 years ago Interferon-free treatment using daclatasvir (Daklinza) and sofosbuvir (Sovaldi), with or without ri......MORE |
Interferon-free hepatitis treatment is highly effective for people with HIV and HCV co-infection in three studiesLiz Highleyman | 8 years ago Three different interferon-free regimens – sofosbuvir/ledipasvir, AbbVie's 3D regimen and grazopr......MORE |
Intensification of antiretroviral therapy reduces risk of late-term mother-to-child HIV transmissionCarole Leach-Lemens | 8 years ago Maternal and infant antiretroviral therapy (ART) intensification is very effective in preventing HI......MORE |
Implant and injectable hormonal contraception most effective methods for women living with HIVCarole Leach-Lemens | 8 years ago Hormonal contraceptive methods are highly effective in reducing the risk of pregnancy in women livi......MORE |
Liver fibrosis regression after hepatitis C treatment linked to reduced complications and death in people with HIV and HCV co-infectionLiz Highleyman | 8 years ago People with HIV and HCV co-infection, with liver cirrhosis, who achieve sustained virological respo......MORE |
Switching to new tenofovir alafenamide keeps virus in check and improves kidney and bone healthLiz Highleyman | 8 years ago People who switch from the current version of tenofovir to tenofovir alafenamide (TAF) – a new fo......MORE |
Raltegravir appears to prevent mother-to-child HIV transmission during late pregnancyLiz Highleyman | 8 years ago Combination antiretroviral therapy containing the integrase inhibitor raltegravir (Isentress) appea......MORE |
PrEP demo project finds the people at highest HIV risk generally take PrEP most consistentlyGus Cairns | 8 years ago An open-label demonstration project of Truvada pre-exposure prophylaxis (PrEP) in the United States......MORE |
Vancouver's treatment as prevention success is also due to harm reduction and addiction treatmentRoger Pebody | 8 years ago “We talk a lot about the success of treatment as prevention in Vancouver, but we always need to m......MORE |
HIV self-testing may help the 'hard to reach' learn their status, but uncertainties remainRoger Pebody | 8 years ago HIV self-testing (or ‘home testing’) is likely to have an important place in future global HIV ......MORE |
Peer-led network intervention substantially lowers HIV infections in people who use drugs in UkraineRoger Pebody | 8 years ago A cluster randomised trial in Ukraine has shown that a peer education project reduced new HIV infec......MORE |
Gay youth PrEP study finds good retention and reasonable adherenceGus Cairns | 8 years ago A US study of pre-exposure prophylaxis in 200 young gay and bisexual men aged 18-22 found reasonabl......MORE |
Giving people information about HIV treatment as prevention lessens stigma and increases testing ratesRoger Pebody | 8 years ago A large randomised trial of communities in rural Malawi shows that a single community meeting provi......MORE |
New NNRTI doravirine suppresses HIV as well as efavirenz but with fewer central nervous system side-effectsLiz Highleyman | 8 years ago Merck's next-generation NNRTI doravirine (formerly known as MK-1439) was found to be as effective ......MORE |
Same-day start to antiretroviral treatment leads to faster HIV suppression in San FranciscoLiz Highleyman | 8 years ago A programme at San Francisco General Hospital that offers antiretroviral therapy (ART) on the same......MORE |
Opioid substitution therapy combined with HIV treatment saves the lives of more drug users than ART aloneKeith Alcorn | 8 years ago Providing opioid substitution therapy (OST) alongside antiretroviral therapy (ART) to people who in......MORE |
Younger gay men have much lower risk of acquiring HIV than previous generations, but racial disparities persistRoger Pebody | 8 years ago An innovative analysis of HIV trends in the Seattle area has found that gay men who were born in th......MORE |
Half of African migrants diagnosed with HIV in France acquired HIV while living thereRoger Pebody | 8 years ago Between a third and a half of African people living with HIV in France probably acquired HIV after ......MORE |
Next-generation maturation inhibitor BMS-955176 shows good antiviral activity in combination with atazanavirLiz Highleyman | 8 years ago The next-generation HIV maturation inhibitor BMS-955176 was well-tolerated and suppressed HIV viral......MORE |
Intermittent PrEP may be a robust strategy for anal sex – vaginal much less certainGus Cairns | 8 years ago The pharmacodynamics (drug absorption and elimination rates) of the two drugs that comprise Truvada......MORE |
‘Nuanced’ sero-adaptive behaviours being used by Australian and American gay menRoger Pebody | 8 years ago There is evidence that some groups of Australian and American gay men are considering HIV-positive ......MORE |
'Nuanced' sero-adaptive behaviours being used by Australian and American gay menRoger Pebody | 8 years ago There is evidence that some groups of Australian and American gay men are considering HIV-positive ......MORE |
Treatment cascades show 90-90-90 goal within reach for some - but Eastern Europe lags behind AfricaKeith Alcorn | 8 years ago Global analysis of HIV treatment cascades – the proportions of people diagnosed with HIV, in care......MORE |
Treatment cascades show 90-90-90 goal within reach for some – but Eastern Europe lags behind AfricaKeith Alcorn | 8 years ago Global analysis of HIV treatment cascades – the proportions of people diagnosed with HIV, in care......MORE |
The Pros and Cons of PrEP: trial volunteers recount their experience of the ADAPT studyGus Cairns | 8 years ago The reasons whether or not people come forward for pre-exposure prophylaxis (PrEP) or take it once ......MORE |
Cash compensation encourages uptake of circumcision, PMTCT servicesKeith Alcorn | 8 years ago Cash compensation can improve the uptake of key HIV prevention services in sub-Saharan Africa, res......MORE |
Active invitation and tracing more likely to get men involved in couples HIV counselling and testingCarole Leach-Lemens | 8 years ago Active invitation and tracing of male partners of pregnant women newly diagnosed with HIV substanti......MORE |
Cash to stay in school doesn’t reduce HIV incidence in South African study – but school attendance protected young women against HIVKeith Alcorn | 8 years ago A conditional cash transfer to the households of adolescent girls to promote school attendance did ......MORE |
START trial provides definitive evidence of the benefits of early HIV treatmentLiz Highleyman | 8 years ago People who start antiretroviral therapy (ART) immediately after HIV diagnosis, while their CD4 cell......MORE |
Innovative approaches to linkage to care boost clinic visits, HIV treatment uptake in African studyKeith Alcorn | 8 years ago A systematic effort to promote HIV testing, linkage to care for people diagnosed with HIV and circu......MORE |
Non-daily PrEP regimens provide extra options, but adherence is often better with daily dosingRoger Pebody | 8 years ago For some people in some settings, less frequent PrEP regimens with doses linked to sexual activity ......MORE |
Targets proliferate in HIV cure researchGus Cairns | 8 years ago The Towards an HIV Cure two-day symposium has become a fixture in advance of the International AIDS......MORE |
No HIV infections from partners with fully suppressed viral load during long-term follow up of landmark treatment as prevention trialKeith Alcorn | 8 years ago Final follow up of the HPTN 052 study of treatment as prevention shows no evidence of HIV transmiss......MORE |
Young woman stays undetectable for twelve years off treatment after early HIV therapyGus Cairns | 8 years ago The 8th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 20......MORE |
Presumptive treatment of TB in advanced HIV no better than giving ART and isoniazidKeith Alcorn | 8 years ago Giving treatment for tuberculosis to all people with very advanced HIV disease at the time they sta......MORE |
Access to screening and treatment are key issues for hepatitis B and C and HIV/viral hepatitis co-infectionLiz Highleyman | 8 years ago The development of effective new interferon-free treatment makes it possible to cure more than 90% ......MORE |
Vancouver Consensus statement calls for early access to treatment and PrEP worldwideKeith Alcorn | 8 years ago Leading figures in the HIV response have endorsed a call for immediate access to antiretroviral the......MORE |
World Health Organization urges more HIV testing by non-medical staff, outside of clinical settings, targeted to those who need it the mostRoger Pebody | 8 years ago In addition to recommending that routine HIV testing in medical settings be expanded to reach new g......MORE |
World Health Organization to recommend HIV treatment for allKeith Alcorn | 8 years ago The World Health Organization will issue new HIV treatment guidelines later this year recommending ......MORE |
Test and treat studies and African countries showing that 90-90-90 targets are achievableRoger Pebody | 8 years ago Health services in some African countries including Botswana, Rwanda and Malawi are now providing e......MORE |
Reaching UNAIDS HIV treatment targets could avert millions of deaths and new infectionsLiz Highleyman | 8 years ago Achieving UNAIDS 90-90-90 targets for getting more people with HIV diagnosed and on antiretroviral ......MORE |
New drug holds out promise of long-term control or even cure of HIVGus Cairns | 8 years ago Scientists at the Scripps Research Institute in California have discovered a new type of drug that ......MORE |
HIV PEP with emtricitabine/tenofovir/rilpivirine has excellent completion and adherence ratesMichael Carter | 8 years ago Daily post-exposure prophylaxis (PEP) with single tablet emtricitabine/tenofovir/rilpivirine (Compl......MORE |
HIV-positive patients in Africa do well on three second-line ART regimensMichael Carter | 8 years ago Three second-line antiretroviral therapy (ART) regimens are equally safe and effective for patients......MORE |
South Africa: Women of lower socio-economic status have greater needs for services to prevent mother-to-child HIV transmissionLesley Odendal | 8 years ago Pregnant women of lower socio-economic status are more likely to take up early HIV testing and to h......MORE |
One step further towards an HIV vaccine: and this one performed as expectedGus Cairns | 8 years ago A recent experimental HIV vaccine protected 50% of a group of twelve rhesus monkeys from infection ......MORE |
Second-line ART patients reach viral re-suppression following intensified adherence supportLesley Odendal | 8 years ago Sixty-seven per cent of all patients who were failing second-line ART achieved viral re-suppressio......MORE |
Black market for Truvada PrEP may undermine treatment adherence in marginalised people living with HIVRoger Pebody | 8 years ago The increasing demand for pre-exposure prophylaxis (PrEP) is likely to increase the likelihood that......MORE |
Community-based adherence clubs show high retention in HIV care and treatment adherenceLesley Odendal | 8 years ago People with HIV who were receiving their HIV treatment outside of health facilities in community-ba......MORE |
Nurse-led palliative care can be successfully integrated into routine HIV services in KenyaMichael Carter | 8 years ago Integrating nurse-led palliative care into routine HIV services has positive effects for the psycho......MORE |
Prompt ART especially important for people with HIV aged 45 and overMichael Carter | 8 years ago Delaying antiretroviral therapy (ART) may have especially serious consequences for middle-aged and ......MORE |
Longer secondary education protects against HIV infection, Botswana study showsKeith Alcorn | 8 years ago Every additional year of schooling among young people in Botswana was associated with an 8% reducti......MORE |
Where next in PrEP and microbicides? Europeans discuss research pipelineGus Cairns | 8 years ago Thursday 18 June saw the final research meeting in Brussels of CHAARM (Combined Highly Active Anti-......MORE |
ART roll-out in Uganda accompanied by increased rates of HIV disclosure to spousesMichael Carter | 8 years ago Roll-out of antiretroviral treatment (ART) has been accompanied by an increase in the proportion of......MORE |
Multiple strategies for safer conception need to incorporate couples' preferencesLesley Odendal | 8 years ago Misunderstandings about serodiscordance and limited understanding of female fertility and male inse......MORE |
Unmet basic needs may be related to poor rates of durable viral suppression among transgender women with HIVMichael Carter | 8 years ago Transgender women living with HIV are less likely to have excellent adherence to antiretroviral tre......MORE |
People with HIV and HCV co-infection who have fibrosis stages F2 and above should be prioritised for new anti-HCV therapiesMichael Carter | 8 years ago People with HIV and hepatitis C virus (HCV) co-infection who have advanced liver fibrosis should be......MORE |
South Africa: Lower coverage of maternal HIV testing among adolescents leading to higher mother-to-child transmissionLesley Odendal | 8 years ago Adolescents have lower coverage of HIV testing and subsequent prevention of mother-to-child (PMTCT)......MORE |
South Africa: Lower coverage of maternal HIV testing among adoelscents leading to higher mother-to-child transmissionKeith Alcorn | 8 years ago Adolescents have lower coverage of HIV testing and subsequent prevention of mother-to-child (PMTCT)......MORE |
HIV stigma decreases with scale-up of HIV treatmentRoger Pebody | 8 years ago In high-prevalence countries of sub-Saharan Africa, the scale-up of HIV treatment appears to have r......MORE |
Liver transplants in HIV/HCV co-infection: study underlines importance of hepatitis C treatmentKeith Alcorn | 8 years ago People with HIV and hepatitis C co-infection were significantly more likely to experience organ re......MORE |
New British guidelines recommend treatment for everyone with HIVKeith Alcorn | 8 years ago Everyone with HIV who is prepared to take antiretroviral treatment should receive it, regardless of......MORE |
Four in ten people diagnosed with HIV in Europe are migrantsGus Cairns | 8 years ago Nearly four out of every ten people with HIV in the European Economic Area (EEA) is a migrant to th......MORE |
Not having enough food linked to poor treatment outcomes in New YorkRoger Pebody | 8 years ago People who don’t have enough food to eat are less likely to have an undetectable viral load than ......MORE |
Living in a stigmatizing country increases HIV risk for MSM in EuropeMichael Carter | 8 years ago Men who have sex with men (MSM) living in European countries with laws and attitudes that stigmatiz......MORE |
Vaginal microbicide ring study releases first data on participantsGus Cairns | 8 years ago An efficacy study of a new method of HIV prevention has published its first data. ASPIRE is one of ......MORE |
Liver function and survival improve after treatment with Viekirax + Exviera regimenLiz Highleyman | 8 years ago Hepatitis C patients treated with AbbVie's Viekirax plus Exviera or '3D' regimen saw improvements i......MORE |
Geriatric conditions common in middle-aged and older HIV-positive menMichael Carter | 8 years ago Geriatric conditions were common in middle-aged and older HIV-positive adults in a San Francisco cl......MORE |
Geriatric HIV: living with multiple medical conditions will become the norm as population agesRoger Pebody | 8 years ago In fifteen years time, the clinical needs of Dutch people living with HIV will have changed substan......MORE |
Consider cannabis use when assessing middle-aged and older patients with HIV, say US investigatorsMichael Carter | 8 years ago Recent cannabis (marijuana) use by middle-aged HIV-positive adults is associated with poor mental h......MORE |
High HCV infection rate in sub-Saharan Africa, with prevalence especially high in patients with HIVMichael Carter | 8 years ago Prevalence of hepatitis C virus (HCV) infection is high in sub-Saharan Africa, according to a repor......MORE |
Acute HCV infections observed among HIV-negative gay men in LondonMichael Carter | 8 years ago Hepatitis C virus (HCV) infections are occurring among HIV-negative gay men in London, investigator......MORE |
Most gay men with HIV in central European capitals are undiagnosed, survey has foundGus Cairns | 8 years ago A survey of gay men in the European cities of Barcelona, Bratislava, Bucharest, Ljubljana, Prague a......MORE |
Hepatitis B and C co-infection linked to worse liver fibrosis than hepatitis B aloneLiz Highleyman | 8 years ago People with both hepatitis B virus (HBV) and hepatitis C virus (HCV) co-infection may experience mo......MORE |
Hepatitis C treatment could halve HCV transmission among gay men in UK over 10 yearsKeith Alcorn | 8 years ago Access to more effective hepatitis C treatment could halve new infections among men who have sex wi......MORE |
Reinfection after hepatitis C cure: prevention may require long-term support for people who have injected drugsKeith Alcorn | 8 years ago Reinfection rates after hepatitis C cure among people who inject drug users, as well as past drug u......MORE |
Sofosbuvir plus daclatasvir for 12 weeks cures most HIV/HCV coinfected patientsLiz Highleyman | 8 years ago Nearly all HIV/HCV coinfected patients treated for 12 weeks with an interferon- and ribavirin-free ......MORE |
Transmitted HIV drug resistance is persistent but is not harming treatment responses in the UKGus Cairns | 8 years ago A study that looks at the genetic makeup of archived samples of drug-resistant HIV in the UK has fo......MORE |
Depression strongly associated with risky sex in UK gay menRoger Pebody | 8 years ago HIV-negative gay men who have several symptoms of depression are more likely to report sex without ......MORE |
Provision of PrEP in the UK will be cost-effective for gay men at high risk of HIV, model findsGus Cairns | 8 years ago A cost-effectiveness model of HIV pre-exposure prophylaxis (PrEP) for gay men based on the data fro......MORE |
Many South African women become infected with HIV during pregnancy posing high risk of transmission to their infantsMichael Carter | 8 years ago There is a high risk of HIV seroconversion during pregnancy for women in South Africa, investigator......MORE |
Harm reduction for people who inject drugs in New York has worked, but hasn’t reduced racial inequalityGus Cairns | 8 years ago Needle and syringe exchange and opiate substitution therapy in New York City has worked in reducing......MORE |
START trial finds that early treatment improves outcomes for people with HIVGus Cairns | 8 years ago A major international randomised clinical trial has found that people living with HIV have a consid......MORE |
High lifetime costs of treating HIV show importance of investing in preventionMichael Carter | 8 years ago The lifetime cost for treating one HIV infection in the UK is almost £380,000, according to a mode......MORE |
Acute HIV infection may present in many ways – sometimes as a serious illnessGus Cairns | 8 years ago A Swiss study of people who were diagnosed during early HIV infection has found that a quarter of t......MORE |
Funders' priorities and targets hindered community mobilisation and meaningful participation of sex workers in IndiaRoger Pebody | 8 years ago Two qualitative studies, investigating the implementation of a massive programme of HIV prevention ......MORE |
Lower daily tenofovir dose of 150mg safe and effective in people with moderate renal impairmentMichael Carter | 8 years ago A reduced tenofovir (Viread) dose of 150mg daily appears to be a safe and effective treatment for p......MORE |
Hepatitis C treatment for people in prison may be highly cost-effective in EnglandKeith Alcorn | 8 years ago Reducing the duration of direct-acting antiviral treatment for hepatitis C will make treatment for ......MORE |
Prioritisation is crucial for the success of PrEP, model confirmsGus Cairns | 8 years ago A mathematical model developed by two researchers at Imperial College in London, and based on what ......MORE |
Statin use associated with lower risk of liver decompensation and death in hepatitis C patients with cirrhosisLiz Highleyman | 8 years ago Hepatitis C patients with liver cirrhosis were significantly less likely to progress to decompensat......MORE |
Inter-connecting health problems increase HIV risk for MSMMichael Carter | 8 years ago Intertwining health problems – syndemics - are associated with higher viral load and poorer adh......MORE |
Civacir immune globulin may help prevent HCV reinfection after liver transplantLiz Highleyman | 8 years ago Civacir, a hepatitis C immune globulin or antibody product, reduced the likelihood of hepatitis C v......MORE |
Gilead triple combination cures easy-to-treat hepatitis C patients in 6 weeks, but 4 weeks is not enoughLiz Highleyman | 8 years ago A 6-week regimen of sofosbuvir (Sovaldi) plus two experimental direct-acting antivirals being devel......MORE |
Shortening hepatitis C treatment to 6 weeks effective but not perfect for easier-to-treat patientsKeith Alcorn | 8 years ago Shortening hepatitis C treatment to 6 weeks for easier-to-treat patients without cirrhosis does not......MORE |
Truvada PrEP causes only mild loss of bone mineral densityMichael Carter | 8 years ago Treatment with tenofovir/emtricitabine (Truvada) as pre-exposure prophylaxis (PrEP) is associated w......MORE |
People with hepatitis C have higher cancer rates, even when excluding liver cancerLiz Highleyman | 8 years ago Hepatitis C patients in the Kaiser Permanente Southern California health maintenance organization h......MORE |
Modern NNRTI regimens can be effective with 85% adherenceMichael Carter | 8 years ago Some modern HIV treatment regimens can achieve viral suppression with adherence rates as low as 85%......MORE |
Modern NNRTI regimens can be effective with 85% adherenceMichael Carter | 8 years ago Some modern HIV treatment regimens can achieve viral suppression with adherence rates as low as 85%......MORE |
Sofosbuvir-based therapy effective for hepatitis C patients with decompensated cirrhosisLiz Highleyman | 8 years ago Interferon-free regimens containing sofosbuvir (Sovaldi) plus simeprevir (Olysio) cured about three......MORE |
Five antiretroviral combinations associated with increased risk of a cardiovascular eventMichael Carter | 8 years ago Treatment with four individual and five combinations of anti-HIV drugs is associated with an increa......MORE |
Gilead triple combination cures easy-to-treat hepatitis C patients in 6 weeks, but 4 weeks is not enoughLiz Highleyman | 8 years ago A 6-week regimen of sofosbuvir (Sovaldi) plus two experimental direct-acting antivirals being devel......MORE |
HIV infection and low CD4 count associated with hardening of arteriesMichael Carter | 8 years ago HIV infection is associated with an increased risk of hardening of the arteries, investigators repo......MORE |
Another study confirms detrimental effects of delaying hepatitis C treatmentLiz Highleyman | 8 years ago Deferring antiviral therapy for hepatitis C until a person progresses to advanced liver disease has......MORE |
When a short course of sofosbuvir/ledipasvir fails, some people can be cured of hepatitis C with a double treatment durationLiz Highleyman | 8 years ago More than 70% of people with chronic genotype 1 hepatitis C who did not achieve a sustained virolog......MORE |
People who don’t tell anyone else their HIV status have as good health outcomes as other people living with HIVRoger Pebody | 8 years ago A large survey of people attending HIV clinics in the UK has found that those individuals who chose......MORE |
Many undiagnosed HIV infections picked up when testing people who have other medical conditions, but implementation challenges remainRoger Pebody | 8 years ago A Europe-wide project offering HIV tests to hospital patients with glandular fever symptoms, swolle......MORE |
Sofosbuvir-based treatment safe and effective in advanced kidney diseaseKeith Alcorn | 8 years ago Sofosbuvir-based direct-acting antiviral therapy for hepatitis C can be used safely and effectively......MORE |
Merck's grazoprevir/elbasvir combo cures 99% of hepatitis C in chronic kidney diseaseKeith Alcorn | 8 years ago The once-daily combination of grazoprevir and elbasvir cured hepatitis C in 99% of people with adva......MORE |
Sofosbuvir plus pegylated interferon/ribavirin is highly effective for people with hard-to-treat genotype 3 hepatitis CLiz Highleyman | 8 years ago A throwback regimen of sofosbuvir (Sovaldi), ribavirin and pegylated interferon taken for 12 weeks ......MORE |
Sofosbuvir, daclatasvir and ribavirin cures hepatitis C for most people with advanced cirrhosis or liver transplantsLiz Highleyman | 8 years ago An interferon-free regimen of sofosbuvir, daclatasvir and ribavirin for 12 weeks produced sustained......MORE |
New EASL guidelines prioritise interferon-free hepatitis C treatmentLiz Highleyman | 9 years ago The European Association for the Study of the Liver (EASL) released its latest hepatitis C treatmen......MORE |
Alcohol misuse the strongest predictor of severe liver damage and death in French people with hepatitis CKeith Alcorn | 9 years ago People with hepatitis C have a much greater risk of liver-related hospitalisation or death if they ......MORE |
Expanded vaccination and treatment could help eliminate hepatitis B worldwideLiz Highleyman | 9 years ago While universal infant hepatitis B virus (HBV) vaccination has already led to major advances in red......MORE |
Grazoprevir/elbasvir highly effective in treatment-experienced a nd HIV-coinfected hepatitis C patientsKeith Alcorn | 9 years ago The combination of grazoprevir and elbasvir without ribavirin is highly effective in curing hepati......MORE |
Advanced liver damage is common in people with undiagnosed hepatitis C in US surveyKeith Alcorn | 9 years ago Around one in five of people with hepatitis C in the United States who do not know of their inf......MORE |
Grazoprevir/elbasvir highly effective in treatment-experienced and HIV-coinfected hepatitis C patientsKeith Alcorn | 9 years ago The combination of grazoprevir and elbasvir without ribavirin is highly effective in curing hepatit......MORE |
First HIV home test approved for sale in UKRoger Pebody | 9 years ago The BioSure HIV Self Test, designed to be used by untrained users at home was granted a CE mark yes......MORE |
Many people living with HIV willing to take part in cure research, despite its risksRoger Pebody | 9 years ago There is a strong interest among people living with HIV in studies towards an HIV cure, with many p......MORE |
Grazoprevir / elbasvir highly effective in previously untreated hepatitis CKeith Alcorn | 9 years ago A 12-week course of the combination of grazoprevir and elbasvir cured 95% of previously untreated p......MORE |
Men taking HIV treatment have undetectable viral loads in the rectum; sexually transmitted infections make no differenceRoger Pebody | 9 years ago A small study assessing the infectiousness of HIV-positive gay men taking antiretroviral therapy ha......MORE |
Sofosbuvir/ledipasvir plus ribavirin shows high cure rate for hepatitis C patients with advanced liver diseaseLiz Highleyman | 9 years ago An oral regimen of sofosbuvir/ledipasvir (Harvoni) and ribavirin taken for 12 or 24 weeks produced ......MORE |
Merck HCV combination effective after failure of first generation of direct-acting antiviralsKeith Alcorn | 9 years ago A 12-week course of treatment with two direct-acting antivirals in development by Merck plus riba......MORE |
Merck HCV combination achieves 90% cure in advanced cirrhosisKeith Alcorn | 9 years ago A 12-week course of treatment with two direct-acting antivirals in development by Merck cured hepat......MORE |
Treatment outcomes no better with single tablet regimens than individual tabletsRoger Pebody | 9 years ago One pill a day HIV treatments such as Atripla, Stribild and Eviplera have the same rates of virolog......MORE |
HCV viral load levels during treatment and speed of decline do not predict cure with interferon-free therapyLiz Highleyman | 9 years ago Direct-acting antiviral regimens containing sofosbuvir (Sovaldi) and the drugs in Viekirax/Exviera ......MORE |
Daily PrEP leads to better adherence and protective drug levels in womenLiz Highleyman | 9 years ago HIV-negative African women assigned to take once-daily Truvada for HIV pre-exposure prophylaxis (Pr......MORE |
High treatment failure rate among Thai children switching to second-line ARTMichael Carter | 9 years ago There is a high treatment failure rate among children taking second-line antiretroviral therapy (AR......MORE |
Annual CD4 count monitoring may be sufficient for people doing well on HIV treatmentMichael Carter | 9 years ago Annual CD4 count monitoring may be sufficient for people taking antiretroviral treatment who have a......MORE |
Newly adopted risk behaviours predict HIV infections in Portuguese gay menRoger Pebody | 9 years ago Changes to an individual’s risk profile – including starting to have unprotected sex with a ste......MORE |
High-dose rifampicin may shorten time to TB clearanceLiz Highleyman | 9 years ago A combination regimen containing high-dose rifampicin (also known as rifampin) was associated with ......MORE |
Women in PrEP trial feared they would have to leave study if they reported low adherenceGus Cairns | 9 years ago Post-study interviews and computer questionnaires conducted with former participants in a trial of ......MORE |
Opioid substitution treatment increases chances that people who inject drugs will have good adherence to HIV therapyMichael Carter | 9 years ago Opioid substitution treatment (OST) increases the chances of people who inject drugs achieving good......MORE |
Global hepatitis B epidemic treatable at cost of just $36 per patient per yearMichael Carter | 9 years ago Large-scale production of generic entecavir could cut the cost of first-line hepatitis B virus (HBV......MORE |
Six in ten US HIV infections are transmitted by people who know they have HIV but are not in careGus Cairns | 9 years ago The majority of HIV in the USA is transmitted by people who know they have HIV but are not in care,......MORE |
End-stage liver disease is a concern for people with HIV and hepatitis B or C co-infectionLiz Highleyman | 9 years ago People with HIV and hepatitis B or C virus co-infection are more likely to progress to end-stage li......MORE |
Ritonavir concentrations not correlated with lipid levels in people with HIV taking boosted atazanavir or boosted darunavirMichael Carter | 9 years ago People taking HIV treatment based on ritonavir-boosted atazanavir and darunavir have comparable lon......MORE |
Cannabis use reduces risk of insulin resistance in people with HIV/HCV co-infectionMichael Carter | 9 years ago Cannabis use is associated with a reduced risk of insulin resistance in people with HIV and hepatit......MORE |
Chinese study sheds light on how well treatment may work as prevention in the real worldGus Cairns | 9 years ago A study from the Henan province of China published recently shows that antiretroviral therapy (ART)......MORE |
HCV sexual transmission linked to anal sex, drug use, lower CD4 countLiz Highleyman | 9 years ago In addition to the usual risk factors for hepatitis C virus (HCV) sexual transmission seen in most ......MORE |
Most HIV-positive gay men in European survey are on HIV treatment, though fewer in the eastGus Cairns | 9 years ago The large EMIS survey of gay men living in Europe has found that over 70% of respondents with HIV a......MORE |
More people in the UK are starting HIV treatment early, in order to reduce their risk of transmissionRoger Pebody | 9 years ago There is evidence of increasing interest in HIV treatment as prevention among people living with HI......MORE |
Adherence support improves ART outcomes in KenyaMichael Carter | 9 years ago The scale-up of antiretroviral therapy (ART) in Kenya is being undermined by high rates of treatmen......MORE |
Early antiretroviral treatment reduces, but does not eliminate HIV reservoirLiz Highleyman | 9 years ago Starting antiretroviral therapy (ART) very soon after infection may limit the size of the HIV 'rese......MORE |
Experimental agents reverse HIV latency and help immune system fight HIV-infected cellsLiz Highleyman | 9 years ago Researchers at the recent Conference on Retroviruses and Opportunistic Infections (CROI 2015) in S......MORE |
Screening for cryptococcal meningitis and adherence support reduce mortality among people starting ART in AfricaMichael Carter | 9 years ago Screening and treatment for cryptococcal meningitis combined with a short period of adherence suppo......MORE |
Good mental health associated with excellent adherence among people taking ART for preventionMichael Carter | 9 years ago Good mental health was the only significant factor associated with optimal pill-taking among people......MORE |
Canada: PrEP use now could save considerable sums in the futureGus Cairns | 9 years ago A Canadian paper that weighs the cost of using pre-exposure prophylaxis (PrEP) to prevent HIV infec......MORE |
Cabotegravir and rilpivirine effective for HIV maintenance therapy at 96 weeksLiz Highleyman | 9 years ago An combination of two once-daily oral antiretrovirals – the next-generation integrase inhibitor c......MORE |
FRAX fracture prediction tool underestimates fracture risk in people with HIVTheo Smart | 9 years ago The Fracture Risk Assessment Tool (FRAX), an online tool developed by the World Health Organization......MORE |
Sustained virological response represents a long-term cure for people with hepatitis C treated with sofosbuvirLiz Highleyman | 9 years ago Almost all patients with hepatitis C virus alone or HIV/HCV coinfection who achieved sustained viro......MORE |
Inflammation and gut leakage remains elevated in people with HIV despite early antiretroviral treatmentLiz Highleyman | 9 years ago Inflammatory changes and damage to the gut begin very soon after initial HIV infection, and may not......MORE |
Screening may miss pre-cancerous anal lesions in women with HIVTheo Smart | 9 years ago Existing algorithms to screen for anal cancer in women living with HIV could be missing many cases ......MORE |
Re-infection due to ongoing risk probably the cause of HCV recurrence after SVRMichael Carter | 9 years ago Rates of hepatitis C virus (HCV) reoccurrence after successful therapy differ markedly between risk......MORE |
Sofosbuvir/ledipasvir raises some antiretroviral levels in HIV/HCV coinfected peopleKeith Alcorn | 9 years ago HIV/HCV coinfected people who take sofosbuvir/ledipasvir (Harvoni) to treat hepatitis C along with ......MORE |
Sofosbuvir/ledipasvir raises some antiretroviral levels in HIV/HCV coinfected peopleLiz Highleyman | 9 years ago HIV/HCV coinfected people who take sofosbuvir/ledipasvir (Harvoni) to treat hepatitis C along with ......MORE |
Studies offer mounting evidence that statins may reduce the risk of heart disease in people living with HIVTheo Smart | 9 years ago Evidence is mounting that statin therapy can prevent the progression of coronary atherosclerosis (......MORE |
We may need to combine many approaches to achieve a cure, delegates hearGus Cairns | 9 years ago It is unlikely that one single approach will achieve a cure for HIV infection, delegates at a commu......MORE |
Does HIV make you fat? Study connects viral load with fat gainsGus Cairns | 9 years ago HIV infection or inflammatory changes associated with it may be responsible for fat accumulation an......MORE |
Screening study finds high prevalence of early-stage lung cancer among smokers with HIVTheo Smart | 9 years ago Using low-dose computed tomography to screen selected people living with HIV who smoke, led to ear......MORE |
Smoking is the biggest risk factor for non-AIDS-defining cancers in people living with HIVTheo Smart | 9 years ago Smoking appears to contribute most to the burden of non-AIDS-defining cancers diagnosed in people l......MORE |
Varenicline helps people with HIV stop smoking, but success rate remains lowLiz Highleyman | 9 years ago The smoking cessation drug varenicline (Champix, or Chantix in the United States) helped more peopl......MORE |
HIV attachment inhibitor BMS-663068 safe and effective in phase 2b studyLiz Highleyman | 9 years ago Bristol-Myers Squibb's BMS-663068 or fostemsavir, a first-in-class HIV attachment inhibitor that s......MORE |
Deferring hepatitis C treatment can lead to liver cancer and death, despite cureLiz Highleyman | 9 years ago HIV/HCV coinfected people who delay hepatitis C treatment remain at risk for liver failure, hepatoc......MORE |
Progression to severe fibrosis or cirrhosis is common among baby boomers with hepatitis C in the USLiz Highleyman | 9 years ago The burden of hepatitis C virus (HCV) infection is high in the US, with a substantial number of in......MORE |
Study finds high rates of cancer among older people living with HIVTheo Smart | 9 years ago Older people living with HIV (over the age of 65) are at greatly increased risk of HIV-associated c......MORE |
Levels of maraviroc in vaginal and rectal tissues may not be high enough for pre-exposure prophylaxisLiz Highleyman | 9 years ago Levels of the HIV entry inhibitor maraviroc (Celsentri/Selzentry) in vaginal and rectal tissues did......MORE |
Financial incentives did not improve linkage to care or viral suppression in US studyGus Cairns | 9 years ago A US study which offered patients gift cards to present themselves for care after testing, and also......MORE |
Tenofovir, boosted atazanavir and boosted lopinavir are associated with cumulative risk of developing chronic kidney diseaseGus Cairns | 9 years ago Three antiretroviral drugs are associated with a slowly increasing rate of chronic kidney disease o......MORE |
Two interferon-free regimens show high HCV cure rates for people with HIV and HCV co-infectionLiz Highleyman | 9 years ago A pair of two-drug, 12-week regimens containing neither interferon nor ribavirin – sofosbuvir (So......MORE |
Tenofovir alafenamide equally effective but safer for kidneys and bones than current formulationLiz Highleyman | 9 years ago Tenofovir alafenamide (TAF), a new formulation that has lower concentrations in the blood but reach......MORE |
Treatment cascades and viral load surveys show how African countries can maximise prevention benefits of HIV treatmentKeith Alcorn | 9 years ago Reaching ambitious HIV prevention targets in South Africa will require intensified efforts to engag......MORE |
Circumcision is reducing HIV incidence in Uganda, Rakai community study showsKeith Alcorn | 9 years ago The growing uptake of medical male circumcision by men in the Rakai district of Uganda is leading ......MORE |
No HIV transmissions from HIV-positive partner seen in Australian gay couples studyGus Cairns | 9 years ago An Australian-based study of gay male couples of opposite HIV status (serodifferent couples) has so......MORE |
US PEPFAR abstinence and faithfulness funding had no impact on sexual behaviour in AfricaKeith Alcorn | 9 years ago Nearly US$1.3 billion spent on US-funded programmes to promote abstinence and faithfulness in sub-S......MORE |
HIV maturation inhibitor BMS-955176 looks promising in early studyLiz Highleyman | 9 years ago A second-generation HIV maturation inhibitor, BMS-955176, demonstrated good safety and high potency......MORE |
Starting HIV treatment at CD4 count above 500 reduces the risk of serious illness and death by 44%, African Temprano trial showsKeith Alcorn | 9 years ago Starting HIV treatment at a CD4 cell count above 500 reduced the risk of serious illness including ......MORE |
Combining PrEP and ART could almost eliminate HIV infection, east African study findsGus Cairns | 9 years ago Giving both pre-exposure prophylaxis (PrEP) and antiretroviral therapy (ART) to heterosexual couple......MORE |
XDR-TB in South Africa is largely spread person-to-person, not by failure of drug treatmentKeith Alcorn | 9 years ago The vast majority of people with extensively drug-resistant tuberculosis (XDR-TB) diagnosed in the......MORE |
Stopping cotrimoxazole during antiretroviral therapy raises risk of bacterial illness, malaria, Ugandan trial showsKeith Alcorn | 9 years ago Stopping cotrimoxazole prophylaxis increases the risk of serious bacterial infections and malaria, ......MORE |
Week-on, weekend-off treatment controls viral load in young peopleKeith Alcorn | 9 years ago Taking an efavirenz-based antiretroviral regimen during the week and taking no medication on two da......MORE |
PrEP use rising in San Francisco, but scaling up could further cut new infectionsLiz Highleyman | 9 years ago Use of Truvada (tenofovir/emtricitabine) pre-exposure prophylaxis, better known as PrEP, is increas......MORE |
Disappointing result for tenofovir-gel microbicide shows that young women still lack HIV prevention methods they can useGus Cairns | 9 years ago Among some highly promising results from HIV prevention studies presented at the Conference on Retr......MORE |
7-country study shows triple-drug combination superior for preventing infant HIV infectionKeith Alcorn | 9 years ago Implementing the World Health Organization (WHO) recommendation of three-drug antiretroviral treatm......MORE |
Breastfeeding mothers often undiagnosed in sub-Saharan AfricaKeith Alcorn | 9 years ago A large proportion of women in sub-Saharan Africa who are at high risk of transmitting HIV to their......MORE |
Pre-exposure prophylaxis also stops 86% of HIV infections in Ipergay studyGus Cairns | 9 years ago A French and Canadian study of pre-exposure prophylaxis (PrEP) presented today at the Conference on......MORE |
Pre-exposure prophylaxis (PrEP) stops 86% of HIV infections in PROUD studyGus Cairns | 9 years ago A study of pre-exposure prophylaxis (PrEP), the English PROUD study, demonstrated the highest effec......MORE |
Local spending on HIV prevention in England plunges to 70p per person, per yearRoger Pebody | 9 years ago HIV prevention in England is underfunded and deprioritised, says the National AIDS Trust (NAT). Whe......MORE |
Low CD4 count important risk factor for oral HPV infection in patients with HIVMichael Carter | 9 years ago A low CD4 count is the single most important risk factor for oral human papillomavirus (HPV) infect......MORE |
Clinicians report two acute HCV infections in Kaiser San Francisco PrEP programmeLiz Highleyman | 9 years ago Two HIV-negative men gay receiving HIV pre-exposure prophylaxis (PrEP) through Kaiser Permanente in......MORE |
HIV testing continues to rise in UK gay men, but safer sex knowledge dropsRoger Pebody | 9 years ago With health services and HIV prevention organisations now having relentlessly focused on HIV testin......MORE |
Researchers may have caught HIV becoming more virulentGus Cairns | 9 years ago A study from Cuba has generated wide media interest because researchers have identified a particula......MORE |
Early antiretroviral treatment reduces seizure risk by two-thirds for children with HIVMichael Carter | 9 years ago Early antiretroviral therapy prevents the development of epilepsy in children with HIV, results of ......MORE |
Patients with HIV can safely receive kidneys from deceased HIV-positive donors, with good five-year survival ratesMichael Carter | 9 years ago HIV-positive patients can safely receive kidneys from deceased HIV-infected donors, investigators f......MORE |
Pilot study suggests that PrEP for other STIs might workGus Cairns | 9 years ago A small pilot study using a daily dose of the antibiotic doxycycline as pre-exposure prophylaxis (P......MORE |
A more personalised approach to hepatitis C treatment may improve adherence and completion ratesRoger Pebody | 9 years ago People receiving treatment for hepatitis C value clinicians who give information and clinical feedb......MORE |
VOICE trial: Microbicide gel may have stopped two out of three HIV infections – in the women who used itGus Cairns | 9 years ago The final published paper on the VOICE trial in women in three African countries mainly reinforces ......MORE |
Men who have sex with men have other health inequalities as well as poor sexual health, say Public Health EnglandRoger Pebody | 9 years ago The UK government’s leading body for public health this week launched a new framework for improvi......MORE |
No improvements in CD4 count at diagnosis in African patients in last decadeGus Cairns | 9 years ago A study by Harvard Medical School has found that the average CD4 count in sub-Saharan African peopl......MORE |
Screening for bone fracture risk should be routine for over-40s with HIV, new guidelines recommendKeith Alcorn | 9 years ago Screening for fracture risk should be a routine part of HIV care for all over-40s, and all postmeno......MORE |
AbbVie next-generation hepatitis C drugs look promising in early studiesLiz Highleyman | 9 years ago AbbVie's investigational HCV protease inhibitor ABT-493 and NS5A inhibitor ABT-530 demonstrated go......MORE |
African American people’s AIDS conspiracy beliefs best understood in terms of social anxiety and distrust, not ignoranceRoger Pebody | 9 years ago The idea that AIDS was created as part of a government-led conspiracy to decimate the African Ameri......MORE |
Smoking is the main cause of increased risk of heart attack in people with HIVRoger Pebody | 9 years ago People living with HIV who smoke have an almost three-fold greater risk of heart attack than HIV-ne......MORE |
Starting HIV treatment early and then interrupting is no better than delaying itGus Cairns | 9 years ago A French study that looked at the total amount of time since infection that people with HIV have sp......MORE |
Many HIV-positive people’s understanding of the law on HIV transmission is “weak and patchy”Roger Pebody | 9 years ago Many people living with HIV in England have a limited understanding of the law which leaves them ei......MORE |
Substance use and social problems predict HIV infection in American gay menRoger Pebody | 9 years ago American gay men reporting depression, childhood sexual abuse, stimulant use, other substance use a......MORE |
Successful peer-recruited project shows it is possible to do prevention work with gay men in hostile environmentsGus Cairns | 9 years ago A community education and HIV prevention project that took place among 626 gay men and other men......MORE |
Improved school attendance credited with reducing HIV infections among teenage girls in UgandaRoger Pebody | 9 years ago The Ugandan government’s decision to abolish tuition fees for school pupils, the resulting improv......MORE |
HCV prevention campaigns need to focus on reducing frequency of injecting drug use involving sharing of equipmentMichael Carter | 9 years ago Sharing injecting equipment is associated with a low per-event probability of hepatitis C virus (HC......MORE |
Gay men are better at predicting when they won’t have sex than when they willGus Cairns | 9 years ago A study in which a group of HIV-negative gay and bisexual men from New York were asked to predict e......MORE |
Elite controllers may pay a high price for their low viral loadGus Cairns | 9 years ago About one in 200 people with HIV maintains an undetectable viral load and high CD4 counts without h......MORE |
Experimental siRNA therapy lowers HBsAg levels in people with hepatitis BLiz Highleyman | 9 years ago ARC-520, a novel therapy using short interfering RNA, appeared safe and was associated with a reduc......MORE |
US guidelines on prevention with people living with HIV now emphasise engagement with care, HIV treatment and social factorsRoger Pebody | 9 years ago The American public health agency, the Centers for Disease Control and Prevention (CDC) has publish......MORE |
Entecavir and tenofovir work well for people with drug-resistant hepatitis B virusLiz Highleyman | 9 years ago A combination of entecavir plus tenofovir effectively suppressed hepatitis B virus (HBV) in people ......MORE |
CDC researchers publish estimate of effectiveness of condom use in anal sexGus Cairns | 9 years ago A paper this month in the Journal of Acquired Immune Deficiency Syndromes finally makes publicly av......MORE |
ART during tuberculosis therapy reduces mortality risk for people with HIVMichael Carter | 9 years ago There is a high mortality rate among people living with HIV undergoing treatment for tuberculosis (......MORE |
One million people with hepatitis C in the US at high priority for treatmentLiz Highleyman | 9 years ago An estimated 813,000 people with diagnosed hepatitis C in the US have undergone liver disease stagi......MORE |
Many hepatitis C patients with cirrhosis or advanced fibrosis face liver failure and liver cancerLiz Highleyman | 9 years ago Nearly one-third of chronic hepatitis C patients with liver cirrhosis and 12% with advanced fibrosi......MORE |
Strategies to improve male partner involvement in microbicide research neededLesley Odendal | 9 years ago Vaginal microbicides were partially developed in response to power differentials within sexual rel......MORE |
UK government halves the budget of HIV prevention programme for EnglandRoger Pebody | 9 years ago The Department of Health’s funding for HIV Prevention England, the national HIV prevention progra......MORE |
Smoking doubles risk of death for patients taking HIV therapyMichael Carter | 9 years ago Smoking doubles the mortality risk for people with HIV taking antiretroviral therapy, a study publi......MORE |
No new HIV infections seen among Kaiser PrEP usersLiz Highleyman | 9 years ago No new HIV infections have occurred among more than 500 users of the Kaiser Permanente healthcare p......MORE |
HIV most often passed on by younger gay men who have undiagnosed HIV, are not on treatment, and have an ongoing partnershipRoger Pebody | 9 years ago A modelling study based on the UK’s HIV epidemic among gay men estimates that two-thirds of infec......MORE |
HIV has become more virulent over time, not less, European study findsGus Cairns | 9 years ago The largest cohort study ever to look at CD4 count and viral loads in HIV-positive people around th......MORE |
Sofosbuvir/ledipasvir cures most previously treated hepatitis C patients with cirrhosisLiz Highleyman | 9 years ago Difficult-to-treat hepatitis C patients with liver cirrhosis who were not cured with a prior course......MORE |
Poor weight gain during first year of ART associated with increased mortality risk for children with HIV in resource-limited settingsMichael Carter | 9 years ago Poor weight gain after starting antiretroviral therapy (ART) is associated with increased mortality......MORE |
European HIV response "falling behind" as Eastern European epidemic growsKeith Alcorn | 9 years ago HIV diagnoses have increased by 80% in the European region since 2004, and three quarters of new HI......MORE |
Reduced physical function significantly increases mortality risk of middle-aged people living with HIVMichael Carter | 9 years ago HIV infection is associated with reduced physical performance, investigators report in the online e......MORE |
Safer injecting practices would be better promoted by focusing on pleasure and practical concerns – not the risk of infectionRoger Pebody | 9 years ago Harm reduction interventions often fail to engage people who inject drugs because they over-emphasi......MORE |
Sofosbuvir/ledipasvir with ribavirin cures most people with hepatitis C recurrence after liver transplantationLiz Highleyman | 9 years ago An interferon-free regimen of sofosbuvir plus ledipasvir (Harvoni) taken with ribavirin for 12 or 2......MORE |
Sofosbuvir + simeprevir shows good results for hepatitis C in real-world useLiz Highleyman | 9 years ago Regimens containing sofosbuvir (Sovaldi) – including sofosbuvir plus simeprevir (Olysio) – work......MORE |
HIV epidemic will spring back without near-universal diagnosis and treatment, says UNAIDSGus Cairns | 9 years ago “Without scale-up, the AIDS epidemic will continue to outrun the response, increasing the long-te......MORE |
British HIV cure survey: most respondents would be prepared to take some health risk to help find a cure for HIVGus Cairns | 9 years ago An online survey that asked people living with HIV, largely from the UK, whether they would partici......MORE |
DAAs show good cure rates and liver function improvement for transplant recipients with recurrent HCVLiz Highleyman | 9 years ago Several presentations at the American Association for the Study of Liver Diseases (AASLD) Liver Mee......MORE |
AbbVie 3D regimen cures recurrent HCV in most liver transplant recipients without cirrhosisLiz Highleyman | 9 years ago AbbVie's 3D regimen (newly named Viekirax + Exviera) demonstrated a sustained virological response ......MORE |
NHS urgently needs to make PrEP available, say HIV prevention organisationsRoger Pebody | 9 years ago A group of community organisations working on HIV prevention have called for the NHS to speed up it......MORE |
Tenofovir continues to suppresses hepatitis B virus for eight yearsLiz Highleyman | 9 years ago Most people with chronic hepatitis B who are treated with tenofovir for eight years continued to ma......MORE |
Tenofovir continues to suppress hepatitis B virus for eight yearsLiz Highleyman | 9 years ago Most people with chronic hepatitis B who are treated with tenofovir for eight years continued to ma......MORE |
Daclatasvir + sofosbuvir demonstrates good cure rate for genotype 3 hepatitis CLiz Highleyman | 9 years ago An all-oral combination of daclatasvir (Daklinza) plus sofosbuvir (Sovaldi), taken for 12 weeks, pr......MORE |
Positive response to 'gift tokens for undetectable viral load' trialGus Cairns | 9 years ago A US study presented at last month’s HIV Research for Prevention conference found generally posit......MORE |
AbbVie 3D regimen and sofosbuvir/ribavirin show high cure rates for HCV in people with HIV co-infectionLiz Highleyman | 9 years ago AbbVie's 3D regimen (paritaprevir/ombitasvir/ritonavir plus dasabuvir) with ribavirin for 12 weeks ......MORE |
Sofosbuvir + GS-5816 for 12 weeks shows high HCV cure rates, but 8 weeks is less effective for some patientsLiz Highleyman | 9 years ago A 12-week oral combination of sofosbuvir plus the experimental NS5A inhibitor GS-5816 demonstra......MORE |
HIV in the UK: 76% diagnosed, 90% on treatment, 90% undetectableRoger Pebody | 9 years ago The UK’s annual epidemiological report, released yesterday, shows that the country already provid......MORE |
Adding pegylated interferon to tenofovir improves odds of HBsAg loss in hepatitis B patientsLiz Highleyman | 9 years ago People with chronic hepatitis B virus (HBV) infection are more likely to experience favourable trea......MORE |
Gay men in UK recommended to receive HPV vaccinationMichael Carter | 9 years ago HPV vaccination programmes should be extended to gay and other men who have sex with men (MSM), an ......MORE |
Merck's grazoprevir/elbasvir combo shows high cure rates, including for people with cirrhosis and HIV/HCV co-infectionLiz Highleyman | 9 years ago An all-oral regimen of grazoprevir (MK-5172) and elbasvir (MK-8742), taken with or without ribaviri......MORE |
Groundbreaking HIV vaccine's effects were real – and could be made to work betterGus Cairns | 9 years ago Findings from further studies using a reformulation of the only HIV vaccine that has ever worked in......MORE |
Sofosbuvir/ledipasvir and AbbVie 3D regimen cure most people with HCV genotype 4Liz Highleyman | 9 years ago Sofosbuvir/ledipasvir without ribavirin and AbbVie's 3D regimen (paritaprevir/ombitasvir plus dasab......MORE |
Restoring and maintaining a high CD4 count possible for vast majority of people living with HIV in FranceAlain Volny-Anne | 9 years ago A large French study has shown that the vast majority of people living with HIV who started treatme......MORE |
Sofosbuvir/ledipasvir with ribavirin is highly effective for people with decompensated cirrhosisLiz Highleyman | 9 years ago An oral regimen of sofosbuvir/ledipasvir plus ribavirin taken for 12 weeks cured most hepatitis C p......MORE |
People living with HIV have high survival rates after liver transplants due to HCCLiz Highleyman | 9 years ago People with HIV – most of whom had hepatitis B or C co-infection – generally had good outcomes ......MORE |
What are the barriers that could stop HIV treatment becoming HIV prevention?Gus Cairns | 9 years ago One of the key strategies involved in trying to bring an end to the HIV epidemic is to increase the......MORE |
Hepatitis B testing and treatment rates are low among U.S. veteransLiz Highleyman | 9 years ago Only 15% of US veterans have been tested for hepatitis B virus (HBV) infection, and among those who......MORE |
Hepatitis B testing and treatment rates are low among US veteransLiz Highleyman | 9 years ago Only 15% of US veterans have been tested for hepatitis B virus (HBV) infection, and among those who......MORE |
Daclatasvir TRIO regimen has good cure rates for hepatitis C patients with or without cirrhosisLiz Highleyman | 9 years ago A 12-week all-oral regimen of daclatasvir, asunaprevir and beclabuvir, with or without ribavirin, c......MORE |
Young drug injectors on opioid maintenance therapy have lower risk of hepatitis C infectionLiz Highleyman | 9 years ago Young people who inject drugs (PWID) who undergo opioid agonist maintenance therapy with methadone ......MORE |
Misunderstanding of questions regarding anal sex in microbicide HIV prevention trialLesley Odendal | 9 years ago There was widespread misunderstanding and misinterpretation of questions about anal sex being asked......MORE |
Once-daily dolutegravir superior to darunavir/ritonavir in 96-week follow-upAlain Volny-Anne | 9 years ago Treatment with a triple antiretroviral combination containing once-daily integrase inhibitor dolute......MORE |
Doravirine works as well as efavirenz with fewer CNS side-effectsLiz Highleyman | 9 years ago Once-daily doravirine (MK-1439), an experimental NNRTI, demonstrated viral suppression similar to ......MORE |
Sofosbuvir/ledipasvir cures nearly all genotype 1 HCV for people with HIV co-infectionLiz Highleyman | 9 years ago All but one participant treated for hepatitis C virus (HCV) with a co-formulation of sofosbuvir an......MORE |
Sustained virological response to hepatitis C treatment reduces mortality, liver cancer and liver transplantsLiz Highleyman | 9 years ago People who achieve sustained virological response (SVR) when treated with interferon-based therapy ......MORE |
Sofosbuvir/ledipasvir cures nearly all genotype 1 HIV/HCV coinfected patientsLiz Highleyman | 9 years ago All but one participant treated with a co-formulation of sofosbuvir and ledipasvir (Harvoni) achiev......MORE |
Protease inhibitor monotherapy: darunavir/ritonavir less effective than three-drug therapyKeith Alcorn | 9 years ago Darunavir/ritonavir monotherapy results in a lower rate of viral suppression after 48 weeks when co......MORE |
Truvada PrEP use rising in United States, especially among menLiz Highleyman | 9 years ago The number of people using Truvada for pre-exposure prophylaxis (PrEP) in the US is increasing and ......MORE |
One third of TB cases in Eastern European HIV clinic survey multi-drug resistantAlain Volny-Anne | 9 years ago Around one-third of people living with HIV in Eastern Europe who were diagnosed with tuberculosis (......MORE |
Australia performs best in HIV treatment cascade – 62% with undetectable viral loadKeith Alcorn | 9 years ago Australia and northern European countries are doing far better than North America at retaining peop......MORE |
Australia performs best in HIV treatment cascade - 62% with undetectable viral loadKeith Alcorn | 9 years ago Australia and northern European countries are doing far better than North America at retaining peop......MORE |
Generic antiretrovirals could save NHS £1.25 billion over 5 years, study findsMichael Carter | 9 years ago Switching all patients taking antiretrovirals in the United Kingdom to generic versions of the drug......MORE |
Efavirenz compromises hormonal contraceptive implantKeith Alcorn | 9 years ago The widely-prescribed non-nucleoside reverse transcriptase inhibitor substantially reduces levels ......MORE |
Do emtricitabine and lamivudine have similar virological efficacy when used in first-line HIV therapy?Michael Carter | 9 years ago First-line antiretroviral regimens containing emtricitabine have superior virological efficacy to c......MORE |
HIV testing and ongoing relationships are part of 'safer sex' for young gay menRoger Pebody | 9 years ago Many young gay men consider ‘safer sex’ to be about more than condom use, according to a qualit......MORE |
Injectable rilpivirine shows promise in phase I trials – but may work better for anal than vaginal sexGus Cairns | 9 years ago A phase one dose-finding and safety study in humans of TMC278 LA, a long-acting, injectable formati......MORE |
Tenofovir gel use associated with lower HSV-2 risk in womenLesley Odendal | 9 years ago The risk of acquiring herpes simplex virus type 2 (HSV-2) was reduced by 46% (aIRR:0.54, 95%CI:0.30......MORE |
Injectable cabotegravir makes progress towards human efficacy studies: doubts about injectable rilpivirineGus Cairns | 9 years ago Researchers have determined the dose of an injectable formulation of the integrase inhibitor cabote......MORE |
Increased expenditure on social security has benefits for TB control in the EUMichael Carter | 9 years ago Increased expenditure on social protection programmes – sickness, disability and unemployment ben......MORE |
Research for Prevention conference opens with real hope for an HIV vaccineGus Cairns | 9 years ago “There’s only one Berlin patient still. But by this time next year he will at least be joined b......MORE |
Second European PrEP study is closed early due to high effectivenessGus Cairns | 9 years ago In an extraordinary development, a second European scientific trial of pre-exposure prophylaxis (Pr......MORE |
Second European PrEP study closes placebo arm early due to high effectivenessGus Cairns | 9 years ago In an extraordinary development, a second European scientific trial of pre-exposure prophylaxis (Pr......MORE |
How does a ‘human rights based approach’ work out on the ground? Lessons from South AfricaRoger Pebody | 9 years ago While international rhetoric on HIV and AIDS frequently invokes human rights, putting these ideas i......MORE |
Emerging epidemic of transmitted HIV drug resistance in low- and middle-income countries, with highest burden seen in MSMMichael Carter | 9 years ago Prevalence of transmitted drug-resistant HIV has doubled in low- and middle-income countries in rec......MORE |
Bedaquiline as part of tailored therapy for MDR- and XDR-TB achieves impressive culture conversion ratesMichael Carter | 9 years ago Use of the new anti-tuberculosis (TB) drug bedaquiline as part of a tailored regimen achieved high ......MORE |
AbbVie 3D HCV regimen well-tolerated in PEARL trialsLiz Highleyman | 9 years ago AbbVie's 3D hepatitis C regimen containing paritaprevir (ABT-450), ombitasvir, and dasabuvir was ge......MORE |
HIV care cascade at Kaiser Permanente varies by sex and ageTheo Smart | 9 years ago Though there has been improving performance of healthcare delivery at each point of the HIV care ca......MORE |
Behavioural and financial incentives may improve HIV treatment outcomesTheo Smart | 9 years ago While making medications free can remove barriers to access for individuals who cannot pay for trea......MORE |
NNRTIs and protease inhibitors both good for first ART, channelling affects choicesLiz Highleyman | 9 years ago Non-nucleoside reverse transcriptase inhibitors (NNRTIs) and boosted protease inhibitors work equ......MORE |
Infants in southern Africa start antiretroviral therapy late with advanced diseaseLesley Odendal | 9 years ago Three quarters of infants starting antiretroviral therapy (ART) across eleven clinics in southern A......MORE |
No to treating our way out of the epidemic, say South African expertsKeith Alcorn | 9 years ago No, we cannot treat our way out of the HIV epidemic, was the resounding sentiment of a panel of exp......MORE |
No to treating our way out of the epidemic, say South African expertsLesley Odendal | 9 years ago No, we cannot treat our way out of the HIV epidemic, was the resounding sentiment of a panel of exp......MORE |
Sofosbuvir/ledipasvir safe and effective for genotype 1 HCVLiz Highleyman | 9 years ago A single-tablet regimen containing the hepatitis C virus (HCV) nucleotide polymerase inhibitor so......MORE |
Inflammatory markers associated with development of diabetes in people taking HIV therapyMichael Carter | 9 years ago Low-level elevations in important markers of systemic inflammation are associated with the developm......MORE |
High effectiveness seen in English PrEP trialGus Cairns | 9 years ago The Steering Committee* of the PROUD trial of pre-exposure prophylaxis (PrEP) in gay men in England......MORE |
Targeted adherence measures and viral load monitoring needed to improve retention in South African ART programmeLesley Odendal | 9 years ago 57% of people living with HIV in South Africa who are eligible to initiate antiretroviral therapy (......MORE |
HIV stigma starts young, but can be corrected, African schoolchildren's study showsGus Cairns | 9 years ago A study conducted among nearly 40,000 school students aged 12 to 14 in nine southern African countr......MORE |
Care programme improves clinic attendance and rates of virologic suppression among vulnerable HIV-positive patients in New YorkMichael Carter | 9 years ago Enrollment in a comprehensive care coordination programme significantly improves levels of engageme......MORE |
HCV core-antigen testing is a reliable way of detecting acute HCV infections in HIV-positive gay menMichael Carter | 9 years ago Hepatitis C virus (HCV) core-antigen testing is a highly reliable way of diagnosing acute HCV infec......MORE |
HIV treatment roll-out has had only a modest impact on mortality in Lusaka, ZambiaMichael Carter | 9 years ago The scale-up of antiretroviral therapy (ART) programmes in Lusaka, Zambia, has been accompanied by ......MORE |
HIV-related stigma has increased in Uganda despite treatment roll-outMichael Carter | 9 years ago HIV continues to be stigmatised despite increased access to antiretroviral therapy (ART), according......MORE |
Counselling during routine HIV care reduces rates of risky sex among people on ART in South AfricaMichael Carter | 9 years ago HIV prevention counselling delivered during routine care reduces sexual risk behaviour in people re......MORE |
The treatment cascade in the United States – good in Ryan White programmes, but overall picture for gay men is poorMichael Carter | 9 years ago People living with HIV in the United States who receive their care through the Ryan White HIV/AIDS ......MORE |
People with hepatitis B who have cirrhosis should be prioritised for liver cancer screeningMichael Carter | 9 years ago Liver cancer screening for people with hepatitis B virus (HBV) infection should be targeted at thos......MORE |
PrEP will need high adherence, high effectiveness and high coverage in specific populations to be affordable in the US, New York study findsGus Cairns | 9 years ago A study based on New York City that modelled pre-exposure prophylaxis (PrEP) uptake there has found......MORE |
Approximately 4.2 million over 50s are now living with HIVMichael Carter | 9 years ago Persuasive new data showing the ageing of the global HIV epidemic has been published in the online ......MORE |
Nearly half of HIV-positive gay men could benefit from being vaccinated against HPV, say Irish researchersGus Cairns | 9 years ago A study of gay men in Ireland that has investigated the prevalence of infection with the human papi......MORE |
Treatment of worm infections leads to increases in CD4 counts and haemoglobin and fall in viral load for HIV-positive women taking ARTMichael Carter | 9 years ago De-worming is associated with falls in viral load and increases in CD4 count and haemoglobin, in pr......MORE |
London gay men: 2% of the population, a quarter of the sexually transmitted infections and half of HIV infectionsRoger Pebody | 9 years ago Men who have sex with men (MSM) living in London have particularly poor sexual health and this is w......MORE |
HIV infection associated with an increased risk of the diseases of ageingMichael Carter | 9 years ago HIV infection is associated with an increased risk of several diseases of old age, according to Dut......MORE |
HCV antibody testing may miss recent infections in gay men living with HIVMichael Carter | 9 years ago Nucleic acid testing should be used to diagnose acute hepatitis C virus (HCV) infections in gay men......MORE |
People living with HIV in the US are infrequently screened for HCVMichael Carter | 9 years ago People living with HIV are infrequently screened for hepatitis C virus (HCV) infection, according t......MORE |
Stigma, ambivalence and other priorities – explaining poor adherence to PrEP and vaginal microbicidesRoger Pebody | 9 years ago HIV stigma, the danger of being mistakenly labelled as having HIV, ambivalence about the research p......MORE |
Drug use strongly associated with sex, condomless sex and STIs in gay men living with HIV in EnglandGus Cairns | 9 years ago A large survey of gay and bisexual men living with HIV and attending eight sexual health clinics in......MORE |
Learning about additional HIV prevention methods doesn’t undermine gay men’s intentions to use condomsRoger Pebody | 9 years ago Health promotion interventions can combine information about condoms and alternative biomedical pre......MORE |
Pregnant women need more support on looking after their own health after childbirth – could help retention in Option B+ programmesRoger Pebody | 9 years ago Many women living with HIV believe that HIV care for the mother’s own health is unimportant once ......MORE |
Longer time to virological failure and less drug resistance seen in people taking Atripla than in people taking separate drugsGus Cairns | 9 years ago An analysis of people who experienced treatment failure on their first-line HIV therapy with a vira......MORE |
HIV testing rates are improving in African people in EnglandRoger Pebody | 9 years ago Data from two large, community surveys of African people living in England suggest that the proport......MORE |
Social inequalities associated with late HIV diagnosis and delayed HIV treatment – European studyRoger Pebody | 9 years ago Even in the context of western European countries with universal access to health care, there are s......MORE |
Poor knowledge of partner HIV status among South African women with recent pregnancyMichael Carter | 9 years ago Over 40% of women with recent pregnancy and a third of men with recent partner pregnancy do not kno......MORE |
Novel immune-suppressant vaccine completely blocks HIV infection in monkeys: human trials plannedGus Cairns | 9 years ago A novel and relatively simple vaccine that can be administered orally has managed to completely blo......MORE |
Late enrolment in HIV care declines in sub-Saharan Africa, but majority of people still eligible for immediate ART at diagnosisMichael Carter | 9 years ago The proportion of HIV-positive patients in sub-Saharan Africa who entered care late declined signif......MORE |
Expanded harm reduction provision achieves impressive reductions in HCV incidence among PWID in ScotlandMichael Carter | 9 years ago Implementation of comprehensive harm reduction policies has achieved impressive reductions in incid......MORE |
HIV superinfection associated with accelerated viral load increase but has no impact on clinical disease progressionMichael Carter | 9 years ago HIV superinfection has no impact on clinical disease progression, investigators report in the onlin......MORE |
Emergent HCV epidemic among young, non-urban people who inject drugs in the United StatesMichael Carter | 9 years ago Incidence of acute hepatitis C virus (HCV) infection increased significantly among young, non-urban......MORE |
CBT counselling significantly increases adherence among participants in HIV PrEP studyMichael Carter | 9 years ago A support intervention based on cognitive behavioural therapy (CBT) significantly improved adherenc......MORE |
Study in Malawi shows importance of screening HIV-positive patients for HBV co-infection and using tenofovir-containing regimensMichael Carter | 9 years ago Hepatitis B virus (HBV) genotype A1 infection is associated with poor virological control and the r......MORE |
Use of drug susceptibility testing to select therapy improves treatment outcomes in patients with MDR- and XDR-TBMichael Carter | 9 years ago New research published in the online edition of Clinical Infectious Diseases supports World Health ......MORE |
HIV prevention for black African people in the UK is under-resourced and needs to be scaled upRoger Pebody | 9 years ago NAT (National AIDS Trust) argues in a recent report that although black African communities in the ......MORE |
Study in South African township shows HIV-negative individuals often source of new TB cases in patients with HIVMichael Carter | 9 years ago HIV-negative individuals are an important source of new tuberculosis (TB) cases in HIV-positive pat......MORE |
Excellent outcomes among people starting HIV therapy at high CD4 counts in UgandaMichael Carter | 9 years ago People in Uganda starting antiretroviral therapy (ART) with higher CD4 counts can achieve excellent......MORE |
Intimate partner violence intervention reduces HIV incidence and violence against womenCarole Leach-Lemens | 9 years ago Integrating intimate partner violence (IPV) prevention strategies into HIV prevention programming l......MORE |
Risk of invasive pneumococcal disease remains high for people living with HIVMichael Carter | 9 years ago People living with HIV continue to be at increased risk of invasive pneumococcal disease, Danish in......MORE |
South African women living with HIV subtype C experience rapid CD4 cell lossMichael Carter | 9 years ago A third of women living with HIV subtype C have a fall in their CD4 count to below 350 cells/mm3 wi......MORE |
Couples-based intervention has impact on HCV incidence and risky sexual behaviour among drug-involved couples in KazakhstanMichael Carter | 9 years ago A couples-based risk reduction intervention reduced hepatitis C virus (HCV) incidence and levels of......MORE |
Self-testing has the potential to boost HIV diagnosis rates among MSM in ChinaMichael Carter | 9 years ago Self-testing has the potential to boost HIV diagnosis rates among high-risk and hard-to-reach men w......MORE |
Mothers starting antiretrovirals in Malawi lost from care more frequently, revealing weaknesses in Option B+ implementationCarole Leach-Lemens | 9 years ago Although Malawi’s policy of offering lifelong antiretroviral therapy (ART) to women living with H......MORE |
Harm reduction prevents HIV, national evidence from Ukraine and Greece showsMara Kardas-Nelson | 9 years ago Two presentations given at the 20th International AIDS Conference, held in Melbourne, Australia Jul......MORE |
Need for scaled up combination prevention for sex workers, Indian and Central American studies showMara Kardas-Nelson | 9 years ago Presentations given at a session considering HIV prevention strategies among female sex workers, wh......MORE |
Switching from first-line ART with suppressed viral load linked to treatment failureLiz Highleyman | 9 years ago People who switch away from their initial antiretroviral therapy (ART) regimen when their viral ......MORE |
Gay men interested in taking PrEP already report high-risk behaviourRoger Pebody | 9 years ago Surveys of gay men in the Netherlands and Australia suggest that some would use condoms less freque......MORE |
Young people with HIV respond well to human papillomavirus vaccineLiz Highleyman | 9 years ago The quadrivalent human papillomavirus (HPV) vaccine worked as well for teens and young adults with......MORE |
What needs to be done to make HIV self-testing a reality?Roger Pebody | 9 years ago Self-testing for HIV has great potential to broaden access to HIV testing, the 20th International A......MORE |
Nearly half of young gay men in Bangkok not using condoms consistently acquire HIV within five years of starting sexGus Cairns | 9 years ago A survey of young gay men and transgender women (MSM) in Bangkok has found that HIV incidence among......MORE |
NAM European HIV prevention survey: final resultsGus Cairns | 9 years ago A pan-European survey of opinions about HIV prevention methods, conducted by NAM last year and answ......MORE |
Of guidelines, targets and resources: the documents that defined the 2014 International AIDS ConferenceGus Cairns | 9 years ago If there was a phrase that defined the 20th International AIDS Conference, one that surfaced in eve......MORE |
Weight gain on ART may raise risk of heart disease and diabetesLiz Highleyman | 9 years ago People with HIV in the normal weight range who gain a substantial amount of weight shortly after st......MORE |
Interferon-free hepatitis C treatment works for people on methadone or buprenorphineLiz Highleyman | 9 years ago People with chronic hepatitis C who are using methadone or buprenorphine to manage opiate addiction......MORE |
Most gay men who don’t use condoms are mindful of HIV and attempt to reduce their riskRoger Pebody | 9 years ago Three-quarters of Australian gay and bisexual men who report unprotected anal intercourse with casu......MORE |
Efavirenz use not linked to neurocognitive impairmentLiz Highleyman | 9 years ago People who use antiretroviral regimens containing efavirenz (Sustiva or Stocrin, also in the Atripl......MORE |
How will people use PrEP? iPrEx users talk condoms, pills, anxiety and reliefGus Cairns | 9 years ago Interviews with participants in the US sites of the iPrEx study of pre-exposure prophylaxis show th......MORE |
The more drugs gay men have taken, the more likely they are to have unprotected sexRoger Pebody | 9 years ago The probability of gay men in England having unprotected anal intercourse is strongly associated wi......MORE |
Tackling moral judgments about sex and sexuality is vital for HIV preventionRoger Pebody | 9 years ago Scientific advances in biomedical prevention and treatment will not reach transgender people, men w......MORE |
ART demand up to 16.8 million by 2016Lesley Odendal | 9 years ago The projected demand for antiretroviral therapy (ART) will increase to 16.8 million person-years by......MORE |
Strong performance on HIV drugs for mothers doesn't guarantee optimal care for infants, survey showsCarole Leach-Lemens | 9 years ago The significant increase in access to antiretroviral therapy for all pregnant women living with HIV......MORE |
HIV is increasing in gay men in London because of lack of testing, comparative study findsGus Cairns | 9 years ago A study presented at the 20th International AIDS Conference (AIDS 2014) in Melbourne today compared......MORE |
Dolutegravir demonstrates good efficacy despite resistanceLiz Highleyman | 9 years ago Antiretroviral regimens containing the recently approved HIV integrase inhibitor dolutegravir (Tiv......MORE |
Could HIV treatment mean safer sex?Gus Cairns | 9 years ago A meta-analysis of every study that has looked at the sexual behaviour of people after starting HIV......MORE |
More data suggest increased risk of HIV infection for women using contraceptive injectionsRoger Pebody | 9 years ago A sophisticated meta-analysis, pooling individual-level data on 37,000 women, has found that the us......MORE |
Reduced treatment delays for people with drug-resistant TB and HIV co-infection through decentralised care and rapid Xpert MTB/RIF testLesley Odendal | 9 years ago Decentralisation of drug-resistant tuberculosis (DR-TB) management and use of the Xpert MTB/RIF tes......MORE |
Anal lesions often resolve without treatment in HIV-positive gay menKeith Alcorn | 9 years ago High-grade anal dysplasia is common among gay men living with HIV, but it often resolves spontaneou......MORE |
Home-testing acceptable in 'treat everyone' trial: treatment takes longer to acceptGus Cairns | 9 years ago The pilot phase of a trial in South Africa that aims to treat everyone living with HIV in a communi......MORE |
Treatment as prevention may not work in Africa without couples counsellingGus Cairns | 9 years ago A study from Zambia has found that a programme of couples voluntary counselling and testing (CVCT),......MORE |
Harm reduction funding meeting only 7% of global needKeith Alcorn | 9 years ago International donors are investing only 7% of what is needed to provide adequate harm reduction cov......MORE |
Maraviroc fails to match tenofovir/emtricitabine for first-line HIV treatmentKeith Alcorn | 9 years ago An NRTI-sparing dual antiretroviral regimen containing maraviroc (Celsentri) plus ritonavir-booste......MORE |
Meta-analysis: only half the people who start PEP complete the courseRoger Pebody | 9 years ago There are significant losses at each step of the post exposure prophylaxis (PEP) ‘treatment casca......MORE |
Globally, 1 in 12 MSM have been arrested for same-sex behaviourRoger Pebody | 9 years ago Laws which criminalise homosexual behaviour – such as those recently passed by Nigeria and Uganda......MORE |
Good adherence seen in study of intermittent PrEPGus Cairns | 9 years ago The first results published from the IPERGAY study, a trial of pre-exposure prophylaxis (PrEP) in g......MORE |
Novel techniques probed in cure researchGus Cairns | 9 years ago Two presentations at the 20th International AIDS Conference in Melbourne described new pathways bei......MORE |
Romidepsin activates latent HIV, but does not decrease viral reservoirLiz Highleyman | 9 years ago The HDAC inhibitor romidepsin was able to awaken latent HIV in resting T-cells, causing it to start......MORE |
Adolescent deaths from AIDS rising, especially among boysCarole Leach-Lemens | 9 years ago While new HIV infections have declined among children, adolescents and adults since 2000, HIV-relat......MORE |
Reappearance of HIV in "Mississippi Baby" poses questions for early treatmentGus Cairns | 9 years ago The 20th International AIDS Conference (AIDS 2014) heard yesterday that the reappearance of HIV in ......MORE |
Cash transfers plus care halve HIV risk behaviours in South African adolescentsCarole Leach-Lemens | 9 years ago Combining unconditional economic support in the form of government cash transfers, school feeding a......MORE |
AIDS 2014: Researchers discuss progress towards an HIV cureLiz Highleyman | 9 years ago Progress along the multi-pronged path towards a cure for HIV was one of the themes at the 20th In......MORE |
Overall PrEP effectiveness in iPrEx OLE study 50%, but 100% in those taking four or more doses a weekGus Cairns | 9 years ago The open-label extension of the iPrEx study of pre-exposure prophylaxis (iPrEx OLE) reported its ma......MORE |
What is needed to 'step up the pace' on HIV prevention and treatment?Keith Alcorn | 9 years ago 'Stepping up the pace', the theme of AIDS 2014, will require a new focus on key populations and ge......MORE |
Significantly less syphilis in female partners of circumcised menGus Cairns | 9 years ago A study presented today at the 20th International AIDS Conference (AIDS 2014) in Melbourne found po......MORE |
Novel TB regimen could reduce treatment durationLesley Odendal | 9 years ago A novel TB drug regimen that could treat drug-sensitive and some forms of drug-resistant TB far mor......MORE |
AbbVie 3D regimen cures most genotype 1 HCV in people with HIV and HCV co-infectionLiz Highleyman | 9 years ago An oral regimen of three direct-acting antivirals plus ribavirin taken for 12 weeks demonstrated a ......MORE |
Sofosbuvir + ribavirin cures hepatitis C for more than 80% of people with HIV and HCV co-infectionLiz Highleyman | 9 years ago An interferon-free regimen of sofosbuvir (Sovaldi) plus ribavirin for 24 weeks led to sustained hep......MORE |
Recession and income inequality have fuelled HIV infections in European drug usersRoger Pebody | 9 years ago In European countries, increases in rates of reported HIV infections among people who inject drugs ......MORE |
AIDS 2014 opening ceremony honours Flight MH17 dead with drive to end AIDS by 2030Keith Alcorn | 9 years ago The 20th International AIDS Conference (AIDS 2014) opened in Melbourne, Australia, on Sunday evenin......MORE |
European CDC cautious about PrEPGus Cairns | 9 years ago The European Centre for Disease Control (ECDC) has issued a paper saying that it cannot make a clea......MORE |
Protease inhibitor therapy doesn't reduce the risk of malaria for HIV-positive pregnant womenMichael Carter | 9 years ago Antiretroviral therapy (ART) based on the protease inhibitor lopinavir/ritonavir does not reduce th......MORE |
Study finds no evidence that HIV-positive gay men in UK have increased risk of neurocognitive impairmentMichael Carter | 9 years ago Prevalence and severity of neurocognitive impairment does not differ between HIV-positive and HIV-n......MORE |
High levels of adherence to study medication among women who conceived during HIV PrEP studyMichael Carter | 9 years ago HIV pre-exposure prophylaxis (PrEP) appears to be an acceptable strategy for safer conception for......MORE |
High rates of drug resistance among HIV-positive infants in South AfricaMichael Carter | 9 years ago There was a high prevalence of antiretroviral drug resistance among infants newly diagnosed with ......MORE |
Therapy with newer, safer antiretrovirals an option for the majority of HIV-positive patientsMichael Carter | 9 years ago The majority of patients taking antiretroviral therapy (ART) that includes drugs associated with ......MORE |
Substantial proportion of male HIV infections labelled as 'heterosexual exposure' in UK probably due to sex with other menMichael Carter | 9 years ago Up to a fifth of HIV infection among black African men initially classified as 'heterosexual exposu......MORE |
HIV prevention needs to support gay men to discuss HIV status and risk, especially in relationshipsRoger Pebody | 9 years ago Gay, bisexual and other men who have sex with men in Scotland rarely talk explicitly about HIV stat......MORE |
HIV/HCV co-infection associated with increased risk of osteoporosis and fracturesMichael Carter | 9 years ago Co-infection with HIV and hepatitis C virus (HCV) is associated with increased risks of low bone ......MORE |
Complex needs and overlapping vulnerabilities frequently reported by ‘high-risk’ gay men in ScotlandRoger Pebody | 9 years ago A quarter of Scottish gay men who are newly diagnosed with HIV or a rectal sexually transmitted inf......MORE |
Protease inhibitor therapy increases underlying genetic risk of diabetes for women with HIVMichael Carter | 9 years ago Treatment with an antiretroviral regimen based on a protease inhibitor magnifies any underlying gen......MORE |
'Robust' evidence of HIV epidemic among people who inject drugs in the Middle East and North AfricaMichael Carter | 9 years ago There is “robust” evidence of HIV epidemics among people who inject drugs (PWID) in multiple co......MORE |
High prevalence of risk behaviour means there's pontential for worsening of HIV epidemic among people who inject drugs in EuropeMichael Carter | 9 years ago Sharing of injecting equipment and sex without condoms is more frequently reported by people who in......MORE |
High prevalence of risk behaviour means there's potential for worsening of HIV epidemic among people who inject drugs in EuropeMichael Carter | 9 years ago Sharing of injecting equipment and sex without condoms is more frequently reported by people who in......MORE |
HCV is a major reason for healthcare utilisation in the United StatesMichael Carter | 9 years ago Patients with hepatitis C virus (HCV) infection are significant users of healthcare services in the......MORE |
Health interventions in online cruising environments more acceptable when they take a ‘passive’ approachRoger Pebody | 9 years ago A survey of men who have sex with men in Scotland has found that sexual health promotion is accepta......MORE |
ART soon after birth for HIV-infected babies can achieve sustained viral suppression and reduce pool of HIV-infected cellsMichael Carter | 9 years ago Antiretroviral therapy started soon after birth can suppress HIV to extremely low levels and severe......MORE |
Gay men who discuss HIV status with sexual partners are less likely to acquire HIVRoger Pebody | 9 years ago A case-control study, examining the sexual behaviour of German gay men receiving HIV-negative and H......MORE |
HIV infection due to unsafe medical injections may have fallen by almost 90% worldwide in decade after 2000Michael Carter | 9 years ago The number of HIV infections in low- and middle-income acquired due to unsafe medical injections by......MORE |
Drug-resistant gonorrhoea rates plummet in USGus Cairns | 9 years ago Preliminary results announced at the US 2014 STD Prevention Conference in Atlanta have shown that t......MORE |
Low uptake of HCV treatment in England will lead to substantial disease burden by 2035Michael Carter | 9 years ago Only 3% of patients with chronic hepatitis C virus (HCV) are treated for their infection each year ......MORE |
PrEP users say it provides an ‘extra layer of protection’ and ‘peace of mind’Roger Pebody | 9 years ago American gay men who have chosen to take pre-exposure prophylaxis (PrEP) are aware of their own ris......MORE |
Current WHO guidelines for use of ART as prevention will benefit only a "fraction" of people with higher CD4 counts and their partnersMichael Carter | 9 years ago World Health Organization (WHO) guidance on the use of antiretroviral treatment (ART) for the preve......MORE |
People starting therapy on a boosted protease inhihibitor don't need to switch after one virological failure episode, study indicatesMichael Carter | 9 years ago Remaining on the same regimen is a “reasonable” strategy for people taking first-line antiretro......MORE |
Three-quarters of women interviewed in Kenya's highest prevalence province say they prefer circumicsed partnersMichael Carter | 9 years ago Women in Kenya generally have a good understanding of the partial protection against infection with......MORE |
Three-quarters of women interviewed in Kenya's highest prevalence province say they prefer circumcised partnersMichael Carter | 9 years ago Women in Kenya generally have a good understanding of the partial protection against infection with......MORE |
Poor infection control procedures lead to HIV transmissions at haemodialysis centre in Saudi ArabiaMichael Carter | 9 years ago Breaches in infection control procedures were associated with genetically linked HIV transmissions ......MORE |
High burden of STIs among people living with HIV in Cape Town in period before they start ARTMichael Carter | 9 years ago Sexually transmitted infection (STI) rates are high among people living with HIV in the period befo......MORE |
Study shows prognostic value of viral load monitoring among people living with subtype C HIV in South AfricaMichael Carter | 9 years ago Viral load is the single most important predictor of CD4 cell loss among people in South Africa who......MORE |
Second analysis concludes that we can't eliminate the long-term possibility of HIV transmission from someone on treatmentGus Cairns | 9 years ago A study that estimates the risk that someone living with HIV and taking antiretroviral therapy coul......MORE |
Second analysis concludes that treatment doesn't eliminate the long-term risk of HIV transmissionGus Cairns | 9 years ago A mathematical model that estimates the risk of HIV transmission from someone taking antiretroviral......MORE |
Model shows potential for substantial long-term HIV risk for serodifferent couples, even with new prevention toolsGus Cairns | 9 years ago A mathematical model derived from the current knowledge about the efficacy of various different pre......MORE |
Model shows potential for substantial long-term HIV risk for serodifferent couples, even with new prevention toolsMichael Carter | 9 years ago A mathematical model derived from current knowledge about the efficacy of various different prevent......MORE |
Men living with HIV have a lower risk of prostate cancerMichael Carter | 9 years ago Incidence of prostate cancer is significantly lower among men living with HIV, investigators from C......MORE |
Tenofovir HIV PrEP causes no long-term harm to kidneysMichael Carter | 9 years ago HIV pre-exposure prophylaxis (PrEP) with tenofovir is associated with mild disturbances in kidney f......MORE |
Action needed to tackle co-infection with HIV and visceral leishmaniasis in IndiaMichael Carter | 9 years ago HIV and visceral leishmaniasis co-infection is “an under-diagnosed and under-recognised emerging ......MORE |
Low vitamin D concentrations associated with poor clinical and virological outcomes among people starting HIV therapyMichael Carter | 9 years ago Low vitamin D concentrations are associated with an increased risk of HIV disease progression among......MORE |
People living with HIV at higher risk of cancers caused by smoking or viruses, but not all cancersMichael Carter | 9 years ago The risk of cancer is increased twofold for people with HIV compared to individuals in the general ......MORE |
New US guidelines recommend PrEPGus Cairns | 9 years ago The US Centers for Disease Control and Prevention (CDC) today released new guidelines recommending ......MORE |
Daily dosing key to the efficacy of tenofovir-based HIV PrEPMichael Carter | 9 years ago Good adherence is key to the efficacy of tenofovir-based HIV pre-exposure prophylaxis (PrEP), accor......MORE |
No significant risk of resistance during treatment with Truvada PrEPMichael Carter | 9 years ago Treatment with pre-exposure prophylaxis (PrEP) does not involve a significant risk of HIV drug resi......MORE |
No significant risk of resistance if HIV infection occurs during use of Truvada PrEPMichael Carter | 9 years ago Treatment with pre-exposure prophylaxis (PrEP) does not involve a significant risk of HIV drug resi......MORE |
Even moderate drinking increases risk of advanced liver fibrosis for people with HIV and HCV co-infectionMichael Carter | 9 years ago Even moderate alcohol consumption is associated with an increased risk of advanced liver fibrosis f......MORE |
Annual HIV tests for high-risk groups and one-off screening for all others could have a big impact on UK's HIV epidemicMichael Carter | 9 years ago The UK’s HIV epidemic could be partially curtailed by annual testing of high-risk groups and one-......MORE |
Sofosbuvir + ribavirin is safe and effective for HCV recurrence after liver transplantationLiz Highleyman | 9 years ago An interferon-free combination of sofosbuvir (Sovaldi) plus ribavirin taken for up to 24 weeks led ......MORE |
Voucher incentives improve engagement with HIV care among people who inject drugsMichael Carter | 9 years ago Providing vouchers exchangeable for food or household goods boosts rates of linkage and retention i......MORE |
Sustained response to treatment reduces fatigue in hepatitis C patientsLiz Highleyman | 9 years ago Curative treatment that eliminates hepatitis C virus from the body can reduce central fatigue, one ......MORE |
Investigational protease inhibitor TMC310911 highly potent in phase 2 studyMichael Carter | 9 years ago The investigational ritonavir-boosted protease inhibitor TMC310911 has a potent antiviral effect, f......MORE |
Sofosbuvir + ribavirin for 24 weeks is highly effective against HCV genotype 4Liz Highleyman | 9 years ago A 24-week regimen of sofosbuvir (Sovaldi) plus ribavirin cured 93% of people with hard-to-treat he......MORE |
Early antiretroviral treatment reduces risk of AIDS and HIV-related illnessMichael Carter | 9 years ago Early antiretroviral therapy significantly reduced the risk of AIDS and HIV-related illness in a la......MORE |
PCR testing reveals high prevalence of CNS infections among people living with HIV in Zambia with CNS symptomsMichael Carter | 9 years ago There is a high prevalence of central nervous system (CNS) opportunistic infections among people li......MORE |
Methadone and buprenorphine-naloxone both associated with reduced HIV risk among people who inject drugsMichael Carter | 9 years ago Methadone maintenance therapy and treatment with buprenorphine-naloxone are equally effective at re......MORE |
Implementation of a comprehensive harm reduction programme curtailed the HIV epidemic among people who inject drugs in TaiwanMichael Carter | 9 years ago Implementation of a comprehensive harm reduction programme successfully contained the HIV epidemic ......MORE |
HIV infection increases risk of melanomaMichael Carter | 10 years ago HIV infection is associated with an increased risk of melanoma, according to the results of a meta-......MORE |
Three-drug AbbVie combination safe and highly effective in treatment of post-transplant hepatitis C recurrenceKeith Alcorn | 10 years ago A three-drug combination of direct-acting antivirals developed by AbbVie cured hepatitis C genotype......MORE |
Sofosbuvir for hepatitis C works well despite multiple negative predictive factorsLiz Highleyman | 10 years ago Hepatitis C treatment using sofosbuvir (Sovaldi) is highly effective even for people with multiple ......MORE |
People living with HIV in the UK still have impaired health-related quality of lifeMichael Carter | 10 years ago People living with HIV in the UK have poorer health-related quality of life (HRQoL) compared to ind......MORE |
Sofosbuvir + new GS-5816 NS5A inhibitor is effective against hepatitis C genotypes 1-6Liz Highleyman | 10 years ago A new experimental NS5A inhibitor, GS-5816, was shown to be safe and effective when used in an inte......MORE |
'Chem sex' commonly reported by UK gay men diagnosed with shigellaMichael Carter | 10 years ago 'Chem sex' (taking recreational drugs during sex) and attendance at sex parties are commonly repo......MORE |
BMS combination cures 90% of genotype 1b hepatitis C in 24 weeksKeith Alcorn | 10 years ago A combination of two direct-acting antivirals developed by Bristol-Myers Squibb (BMS) cured 90% of ......MORE |
Sofosbuvir + ribavirin is safe and effective for people with hepatitis C who have advanced liver diseaseLiz Highleyman | 10 years ago Sofosbuvir plus ribavirin is a safe option that can lead to sustained response in people with advan......MORE |
Abolishing HIV in RwandaGus Cairns | 10 years ago The achievement of universal HIV coverage in one African country, Rwanda, has resulted in HIV diagn......MORE |
Adding interferon to nucleoside antivirals may improve response for people with chronic hepatitis BLiz Highleyman | 10 years ago Adding pegylated interferon to entecavir (Baraclude) led to greater hepatitis B virus (HBV) viral l......MORE |
AbbVie 3-drug combination cures 92 to 96% of hepatitis C patients with cirrhosisKeith Alcorn | 10 years ago The largest study of new direct-acting antivirals yet conducted in people with hepatitis C genotype......MORE |
AbbVie 2-drug combination + ribavirin achieves 100% cure in previously untreated genotype 4 hepatitis CKeith Alcorn | 10 years ago A combination of two direct-acting antivirals developed by AbbVie cured 100% of previously untreate......MORE |
Sofosbuvir/ledipasvir coformulation cures more than 90% of treatment-naive and retreated genotype 1 patientsLiz Highleyman | 10 years ago A coformulation of sofosbuvir and ledipasvir taken for as little as 8 weeks produced high sustaine......MORE |
Sofosbuvir/ledipasvir co-formulation cures more than 90% of treatment-naive and retreated genotype 1 patientsLiz Highleyman | 10 years ago A co-formulation of sofosbuvir and ledipasvir taken for as little as eight weeks produced high sus......MORE |
Sofosbuvir + simeprevir dual therapy shows high cure rates for hepatitis C patients with or without cirrhosisLiz Highleyman | 10 years ago A 12-week oral regimen of sofosbuvir (Sovaldi) plus simeprevir (Olysio) without pegylated interfero......MORE |
European liver specialists recommend `mix-and-match` approach to new hepatitis C drugsKeith Alcorn | 10 years ago The European Association for the Study of the Liver has issued new guidelines for the treatment of ......MORE |
European liver specialists recommend 'mix-and-match' approach to new hepatitis C drugsKeith Alcorn | 10 years ago The European Association for the Study of the Liver (EASL) has issued new guidelines for the treatm......MORE |
Sofosbuvir/ledipasvir produces early cure for 100% of people with HIV and HCV co-infectionLiz Highleyman | 10 years ago Treatment for 12 weeks with a co-formulation of sofosbuvir and ledipasvir led to sustained respons......MORE |
Sofosbuvir/ledipasvir produces early cure for 100% of HIV/HCV coinfected patientsLiz Highleyman | 10 years ago Treatment for 12 weeks with a coformulation of sofosbuvir and ledipasvir led to sustained response......MORE |
Sofosbuvir/ledipasvir is safe and effective for relapsers and hard-to-treat patientsLiz Highleyman | 10 years ago A coformulation of sofosbuvir and ledipasvir successfully treated a variety of difficult-to-treat p......MORE |
88% of previous relapsers achieve hepatitis C cure with simeprevir-based triple therapyKeith Alcorn | 10 years ago Almost 90% of European patients who had relapsed after previous treatment with pegylated interferon......MORE |
AbbVie interferon-free regimen cures 96% of treatment-experienced genotype 1 hepatitis C infectionsKeith Alcorn | 10 years ago A 12-week course of three direct-acting antivirals developed by AbbVie, plus ribavirin, cured 96.3%......MORE |
Can we provide point-of-care viral load tests in poor countries?Gus Cairns | 10 years ago It is not impossible to provide mobile, point-of-care viral load tests in resource-poor settings, t......MORE |
PROUD UK PrEP study completes enrolment - first data gives participants' background and risk factorsGus Cairns | 10 years ago The pilot stage of the PROUD study - the UK's study of HIV pre-exposure prophylaxis (taking HIV dru......MORE |
PROUD UK PrEP study completes enrolment – first data give participants' background and risk factorsGus Cairns | 10 years ago The pilot stage of the PROUD study – the UK's study of HIV pre-exposure prophylaxis (HIV-negative......MORE |
WHO recommends global use of newest hepatitis C drugs, urges price reductionsKeith Alcorn | 10 years ago The World Health Organization has issued global treatment guidelines for hepatitis C, strongly reco......MORE |
Low CD4 count during HIV therapy increases risk of virus-related non-AIDS cancersMichael Carter | 10 years ago A poor CD4 response to antiretroviral therapy (ART) is associated with an increased risk of virus-r......MORE |
Giving treatment to specific high-risk people may bring down HIV faster than distributing it equallyGus Cairns | 10 years ago In a concentrated epidemic, HIV is mainly restricted to – or at least more common in – specific......MORE |
Expanded HIV testing may find more acute infections as well as more late presentersGus Cairns | 10 years ago Expanding HIV testing into local hospitals and primary care may not only find more people who have ......MORE |
Home sampling for HIV testing – high demand, 1 in 60 are HIV positiveRoger Pebody | 10 years ago Pilot projects, testing innovative ways for individuals to take their own saliva or blood sample an......MORE |
Home sampling for HIV testing – high demand, 1 in 60 are HIV positiveRoger Pebody | 10 years ago Pilot projects, testing innovative ways for individuals to take their own saliva or blood sample an......MORE |
An estimated 29,000 undiagnosed HIV cases in FranceMichael Carter | 10 years ago An estimated 29,000 individuals in France were living with undiagnosed HIV infection in 2010, inves......MORE |
No simple relationship between drug use and risky sex in London gay menRoger Pebody | 10 years ago Gay men involved in ‘chemsex’ (taking recreational drugs such as mephedrone, GHB/GBL and crysta......MORE |
Standard HIV treatment achieves high concentrations in female genital tract and suppresses shedding of virusMichael Carter | 10 years ago Standard antiretroviral therapy containing tenofovir, FTC and atazanavir achieves high concentratio......MORE |
HIV viral load in semen can differ in two samples provided within one hourMichael Carter | 10 years ago HIV can be intermittently detectable in the semen of men taking long-term antiretroviral therapy th......MORE |
Risk score can help predict which people living with HIV have highest risk of kidney disease during tenofovir treatmentMichael Carter | 10 years ago Investigators in the United States have developed a risk score to predict which people living with ......MORE |
Hepatitis delta virus co-infection increases risk of poor liver-related outcomes for people living with HIVMichael Carter | 10 years ago Co-infection with hepatitis delta virus (HDV) is a major risk factor for hepatic decompensation and......MORE |
South African treatment guidelines need to consider viral load, not CD4 count, to achieve greater impact of treatment as prevention: studyMichael Carter | 10 years ago Recommendations about the initiation of antiretroviral therapy (ART) need to change for the use of ......MORE |
Interferon-free BMS combo cures 90% of genotype 1 hepatitis CLiz Highleyman | 10 years ago An all-oral regimen of daclatasvir, asunaprevir and BMS-791325 – without interferon or ribavirin ......MORE |
HIV incidence is high among pregnant and postpartum women and increases the risk of mother-to-child transmissionMichael Carter | 10 years ago HIV incidence is high among pregnant and postpartum women and is associated with an increased risk ......MORE |
Merck combination suppresses HCV in mono-infected and co-infected patientsLiz Highleyman | 10 years ago An all-oral combination of the hepatitis C virus (HCV) protease inhibitor MK-5172 and NS5A inhibito......MORE |
Early treatment reduces viral reservoirs but does not prevent reboundLiz Highleyman | 10 years ago Antiretroviral therapy started during the first several days after infection limited dissemination ......MORE |
Dapivirine vaginal ring safe and effective in tissue study, but maraviroc component doesn't workLiz Highleyman | 10 years ago Vaginal rings containing the experimental NNRTI dapivirine were well tolerated and blocked HIV infe......MORE |
Early antiretroviral therapy may limit gut damage and immune activationLiz Highleyman | 10 years ago Starting antiretroviral therapy (ART) at the earliest stage of HIV infection can help prevent immun......MORE |
Women with circumcised partners less likely to have HIV, no less likely to use condomsGus Cairns | 10 years ago A study from Orange Farm near Johannesburg in South Africa, the area that hosted the first-ever ran......MORE |
High rate of new infections with HPV types associated with a high risk of anal cancer among gay men living with HIVMichael Carter | 10 years ago Incidence of anal infection with cancer-associated strains of human papillomavirus (HPV) is high am......MORE |
Monitoring may be an option for people living with HIV diagnosed with high-grade pre-cancerous anal lesionsMichael Carter | 10 years ago Up to 62% of people living with HIV who have high-grade pre-cancerous cell changes may experience a......MORE |
Rare case of lesbian transmission of HIV reported in USMichael Carter | 10 years ago An extremely rare case of female-to-female sexual transmission of HIV has been reported in the Unit......MORE |
Very different levels of PrEP uptake and adherence in three US cities, demonstration project findsGus Cairns | 10 years ago One of the first studies of open-label pre-exposure prophylaxis (PrEP) for at-risk gay men in three......MORE |
Heart attack link to abacavir persists in D:A:D studyGus Cairns | 10 years ago The nucleoside (NRTI) drug abacavir (Ziagen also in Kivexa/Epzicom) continues to be associated with......MORE |
Daclatasvir plus simeprevir are effective against hepatitis C genotype 1bLiz Highleyman | 10 years ago An all-oral regimen of daclatasvir plus simeprevir, without interferon or ribavirin, led to sustain......MORE |
Efavirenz-based ART matches lopinavir/ritonavir for perinatal HIV treatmentCarole Leach-Lemens | 10 years ago Pregnant women taking efavirenz-based antiretroviral therapy had significantly better virologic out......MORE |
Massive scale-up of HIV testing, plus HIV treatment on diagnosis, needed to curtail UK gay epidemicRoger Pebody | 10 years ago Increasing the proportion of HIV-positive gay men in the UK who have an undetectable viral load fro......MORE |
Only having sex with same-status partners is an HIV prevention strategy for 40% of gay menGus Cairns | 10 years ago A study from Seattle has found that only having sex with men of the same HIV status was by far the ......MORE |
Rejecting serodiscordant partners is HIV prevention strategy of choice for 40% of gay menGus Cairns | 10 years ago A study from Seattle has found that avoiding men of the opposite HIV status was by far the most com......MORE |
Sexually transmitted infections greatly increase the risk of HIV infection in pregnancyCarole Leach-Lemens | 10 years ago Pregnant women in Kenya have a similar risk of HIV infection during pregnancy to serodiscordant cou......MORE |
New NNRTI doravirine matches efavirenz for first-line HIV treatmentLiz Highleyman | 10 years ago The next-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) doravirine (formerly MK-......MORE |
Lopinavir/ritonavir or 3TC PrEP equally protective against infant HIV infection during breastfeedingCarole Leach-Lemens | 10 years ago Lopinavir/ritonavir (Kaletra) or 3TC (lamivudine, Epivir) proved equally protective as infant proph......MORE |
Heart attack risk in people with HIV may be falling – but not in womenGus Cairns | 10 years ago A number of studies at last week’s Conference on Retroviruses and Opportunistic Infections (CROI)......MORE |
Nipping HIV in the bud: could we use genotyping to interrupt transmission?Gus Cairns | 10 years ago The Conference on Retroviruses and Opportunistic Infections (CROI) this year heard a number of pres......MORE |
Novel two-drug maintenance combination works at least as well as triple therapy: stage set for long-lasting injectable formulationGus Cairns | 10 years ago An oral combination therapy of two antiretroviral drugs, the non-nucleoside rilpivirine (Edurant, a......MORE |
Protected T-cells persist and proliferate in HIV gene therapy studyLiz Highleyman | 10 years ago Genetically modified CD4 T-cells lacking CCR5 co-receptors reach high levels in the body and are re......MORE |
Raltegravir has the edge over two protease inhibitors in three-drug comparison studyGus Cairns | 10 years ago In a head-to-head comparison of three drugs presented at the 21st Conference on Retroviruses and Op......MORE |
The 'Boston patients' experience HIV rebound after stem cell transplantsLiz Highleyman | 10 years ago HIV has re-emerged in two Boston men who underwent experimental antiretroviral therapy interruption......MORE |
Younger women not at higher risk of HIV from relationships with older men, South African study findsKeith Alcorn | 10 years ago Sex with older men is not placing women under 30 at higher risk of HIV infection in rural South Afr......MORE |
Self-testing encourages very high uptake of HIV testing in Malawi studyKeith Alcorn | 10 years ago A community-based self-testing programme achieved 76% uptake of HIV testing in urban Malawi, with v......MORE |
Male life expectancy nine years shorter due to lower male uptake of HIV treatment in rural South AfricaKeith Alcorn | 10 years ago Male life expectancy in rural South Africa has improved far less dramatically than women’s life e......MORE |
Raltegravir plus boosted darunavir shown to be safe and effective for first-line ARTLiz Highleyman | 10 years ago An NRTI-sparing initial regimen of raltegravir (Isentress) plus boosted darunavir (Prezista) worked......MORE |
HIV attachment inhibitor BMS-663068 shows good safety and efficacy in phase 2b studyLiz Highleyman | 10 years ago Combination therapy using a novel HIV attachment inhibitor demonstrated good safety and effectivene......MORE |
Maternal deaths due to HIV not declining despite PMTCT successes in South AfricaKeith Alcorn | 10 years ago Improvements in prevention of mother-to-child transmission of HIV (PMTCT) in South Africa are not t......MORE |
HIV incidence at record high in young gay black men in southern USAGus Cairns | 10 years ago HIV incidence in young black gay men in Atlanta, Georgia in the US is running at 12.1% a year – o......MORE |
People with HIV more likely to die after diagnosis of many common cancers in USKeith Alcorn | 10 years ago People with HIV are more likely to die from many common cancers than the rest of the US population,......MORE |
Monkey studies confirm viability of injectable PrEP drugGus Cairns | 10 years ago Two studies in monkeys of an injectable formulation of the third-generation integrase inhibitor dr......MORE |
Sofosbuvir & ribavirin cures 75% of genotype 1 HIV/HCV co-infected patientsLiz Highleyman | 10 years ago An interferon-free regimen of sofosbuvir plus ribavirin for 24 weeks led to sustained response in t......MORE |
AbbVie '3D' combination cures 99% of genotype 1b hepatitis CKeith Alcorn | 10 years ago A 12-week triple combination of direct-acting antivirals developed by AbbVie cured at least 99% of ......MORE |
Simeprevir cures almost 80% of first-time coinfected hepatitis C patientsKeith Alcorn | 10 years ago The next-generation hepatitis C protease inhibitor simeprevir cured almost 80% of previously untre......MORE |
Simeprevir cures almost 80% of first-time co-infected hepatitis C patientsKeith Alcorn | 10 years ago The next-generation hepatitis C protease inhibitor simeprevir cured almost 80% of previously untre......MORE |
Faldaprevir plus interferon and ribavirin cures hepatitis C in most people with HIV/HCV co-infectionLiz Highleyman | 10 years ago The hepatitis C protease inhibitor faldaprevir added to pegylated interferon and ribavirin cured he......MORE |
Six-week oral treatment can cure hard-to-treat hepatitis C patientsLiz Highleyman | 10 years ago Interferon- and ribavirin-free treatment using sofosbuvir, ledipasvir and a third direct-acting dru......MORE |
No-one with an undetectable viral load, gay or heterosexual, transmits HIV in first two years of PARTNER studyGus Cairns | 10 years ago The second large study to look at whether people with HIV become non-infectious if they are on anti......MORE |
A cure may need multiple components, workshop delegates hearGus Cairns | 10 years ago Delegates at the community cure workshop in advance of the 21st Conference on Retroviruses and Oppo......MORE |
Older age associated with bigger increases in viral load and falls in CD4 count in patients not taking HIV treatmentMichael Carter | 10 years ago Results of a large observational study underline the importance of closely monitoring viral load in......MORE |
Reconnecting patients lost to follow-up with care can prevent new HIV transmissionsMichael Carter | 10 years ago The number of HIV transmissions can be reduced by tracing patients who drop out of HIV care, accord......MORE |
Big gaps in engagement with HIV care and virological suppression between US statesMichael Carter | 10 years ago The proportion of people living with HIV linked to and retained in HIV care varies considerably bet......MORE |
Guidelines for HIV testing in non-specialist settings not being followed in the UKMichael Carter | 10 years ago UK guidelines issued in 2008 concerning HIV testing in general medical and primary care settings ar......MORE |
HIV treatment as prevention: the Ugandan experienceMichael Carter | 10 years ago Antiretroviral therapy (ART) is associated with a substantial and sustained reduction in the risk o......MORE |
Young people who acquire HIV in Uganda report poor communication and mistrust in their relationshipsRoger Pebody | 10 years ago Compared with young people who remain HIV negative, recent seroconverters in Rakai, Uganda describe......MORE |
HIV treatment as prevention: the experience in British ColumbiaMichael Carter | 10 years ago Expanded coverage of HIV therapy in British Columbia has been accompanied by a 42% reduction in HIV......MORE |
Truvada PrEP does not harm the kidneys, trial showsMichael Carter | 10 years ago HIV pre-exposure prophylaxis (PrEP) with FTC/tenofovir (Truvada) is associated with only mild distu......MORE |
HIV prevalence and incidence fall in KenyaMichael Carter | 10 years ago HIV incidence and prevalence are declining in Kenya, investigators report in the online edition of ......MORE |
A low CD4 cell count despite viral suppression with HIV treatment is associated with a big increase in mortality riskMichael Carter | 10 years ago A low CD4 cell count is associated with increased mortality risk, even if people are taking virolog......MORE |
Wide range of factors contribute to high HIV risk among black MSM in the USMichael Carter | 10 years ago Demographic, behavioural, economic and biological factors are all associated with increased HIV ris......MORE |
Dosing errors of liquid AZT "exceedingly" common and related to poorer HIV health literacyMichael Carter | 10 years ago Dosing errors are “exceedingly” common when adults are preparing paediatric doses of liquid ant......MORE |
Unprotected receptive anal sex is the key risk factor among UK gay men for rectal LGV infectionMichael Carter | 10 years ago Unprotected receptive anal sex is the key risk factor for rectal LGV (lymphogranuloma venereum) inf......MORE |
Black people have low levels of engagement and retention in HIV care in the USMichael Carter | 10 years ago Intensified efforts are needed to improve engagement by black people in the HIV care continuum in t......MORE |
High incidence of antiretroviral prescribing errors in NigeriaMichael Carter | 10 years ago Antiretroviral prescribing errors are common in Nigeria, according to results of a large prospectiv......MORE |
‘Not quite normal’ – exploring poor mental health in gay menRoger Pebody | 10 years ago Although legal and social equality for gay people is further advanced in the Netherlands than in mo......MORE |
HIV associated with increased risk of MDR-TBMichael Carter | 10 years ago HIV infection is associated with an increased risk of multi-drug-resistant tuberculosis (MDR-TB), r......MORE |
HIV increases fracture risk, say DanesMichael Carter | 10 years ago HIV infection increases the risk of fractures, Danish investigators report in the online edition of......MORE |
Close link between HIV and hepatitis C transmission networksMichael Carter | 10 years ago HIV and hepatitis C virus (HCV) transmission networks are closely linked, according to Swiss resear......MORE |
HIV testing interventions should challenge fears of a positive resultRoger Pebody | 10 years ago Among gay and bisexual men in Glasgow, not having recently taken an HIV test is associated with bei......MORE |
Higher pill burden is associated with poorer adherence to HIV therapy and reduced chances of achieving an undetectable viral loadMichael Carter | 10 years ago Lower pill burden is associated with higher rates of adherence to HIV treatment and better virologi......MORE |
Gay and bisexual men in UK warned of Shigella outbreakMichael Carter | 10 years ago Gay and bisexual men in the UK are being targeted with a new health information campaign warning th......MORE |
US medical societies launch new hepatitis C treatment guidelinesLiz Highleyman | 10 years ago The American Association for the Study of Liver Diseases (AASLD), Infectious Diseases Society of Am......MORE |
Average CD4 cell count at time HIV therapy was started increased among young people in New York City after 2009Michael Carter | 10 years ago The average CD4 cell count at which young people living with HIV in New York City started antiretro......MORE |
Taking one to tango: how restricting responsibility for safer sex to individuals hinders talking about safer sexGus Cairns | 10 years ago A discussion paper based on a Canadian project that invited HIV-negative and HIV-positive gay men t......MORE |
Successful HIV drug resistance testing is possible when viral load is lowMichael Carter | 10 years ago HIV drug resistance testing can perform well, even when viral load is as low as 250 copies/ml, resu......MORE |
Ongoing challenges in providing PMTCT in Kenya and MalawiLesley Odendal | 10 years ago Ongoing systemic issues are affecting the implementation of the 2010 World Health Organisation (WHO......MORE |
Significant attrition at each step of the HIV care 'cascade' in British ColumbiaMichael Carter | 10 years ago Patients are being lost at each stage of the HIV care ‘cascade’ in British Columbia, Canada. In......MORE |
Long-term immune response to vaccines is impaired in people with HIVMichael Carter | 10 years ago The long-term immune response to most vaccines is impaired in people with HIV, according to the res......MORE |
Cotrimoxazole prophylaxis neither reduces TB risk nor complicates TB diagnosis in people with HIVMichael Carter | 10 years ago Cotrimoxazole prophylaxis has no impact on incidence or detection of tuberculosis (TB) in people wi......MORE |
Modelling study – self testing could lead to more HIV infectionsRoger Pebody | 10 years ago If gay men replace clinic-based HIV testing with less sensitive home tests, the prevalence and inci......MORE |
Testing HCV positive has a sustained impact on drug injecting behaviourMichael Carter | 10 years ago Diagnosis with hepatitis C virus (HCV) is associated with a sustained reduction in injecting drug u......MORE |
Gay men’s HIV risk varies hugely between individuals and over time, cohort study findsGus Cairns | 10 years ago A study that looked at the way risk of HIV transmission changed over time in a group of gay men dur......MORE |
Low lymphocyte count a risk factor for infections for people taking HCV therapyMichael Carter | 10 years ago A low lymphocyte count is associated with an increased risk of infections during hepatitis C virus ......MORE |
Opt-out HIV testing for acute medical admissions to UK hospitals worksMichael Carter | 10 years ago Opt-out HIV testing for general medical admissions to hospital is feasible, cost-effective and lead......MORE |
Immune suppression associated with reduced risk of TB transmission to household contacts of people with HIV/TB co-infectionMichael Carter | 10 years ago HIV-related immune suppression is associated with a reduced risk of tuberculosis (TB) transmission ......MORE |
Computerised counselling for patients taking HIV therapy can reduce viral load, improve treatment adherence and reduce rates of risky sexMichael Carter | 10 years ago Computerised counselling can achieve reductions in viral load and HIV transmission risk behaviour, ......MORE |
Study identifies factors associated with mortality in HIV-positive people with cryptococcal meningitisMichael Carter | 10 years ago Rapid diagnosis and effective antifungal therapy are essential to reduce mortality rates in HIV-pos......MORE |
Regular clinic attendance especially beneficial for people with HIV who have low CD4 countsMichael Carter | 10 years ago People taking HIV treatment who have a low CD4 cell count are especially likely to achieve an undet......MORE |
High viral load levels in young people newly linked with HIV care in the USMichael Carter | 10 years ago Approximately a third of young people newly linked to HIV care in the United States have viral load......MORE |
African studies identify strategies for improving treatment adherence, retention in careMara Kardas-Nelson | 10 years ago Getting people tested for HIV is one thing; getting them onto antiretrovirals (ARVs) another; and r......MORE |
TB/HIV programmatic challenges highlighted at ICASALesley Odendal | 10 years ago The presence of tuberculosis (TB) at the initiation of antiretroviral therapy (ART) predicts retent......MORE |
Life expectancy now considerably exceeds the average in some people with HIV in the USGus Cairns | 10 years ago A study from the US has found that some groups of people with HIV, especially those treated before ......MORE |
Large US study shows which HIV tests are most accurateRoger Pebody | 10 years ago Differences in the performance of commonly used HIV tests lead to substantial differences in the nu......MORE |
People newly diagnosed with HIV/STIs often have individuals with undiagnosed HIV in their social networkMichael Carter | 10 years ago Asking people who are newly diagnosed with HIV or a sexually transmitted infection (STI) to recruit......MORE |
Patients newly diagnosed with HIV/STIs often have individuals with undiagnosed HIV in their social networkMichael Carter | 10 years ago Asking patients newly diagnosed with HIV or a sexually transmitted infection (STI) to recruit conta......MORE |
Short course of ART during primary HIV therapy has immunological and virological benefits after treatment is stoppedMichael Carter | 10 years ago A short course of antiretroviral therapy during primary HIV infection (PHI) has immunological and v......MORE |
Short course of ART during primary HIV infection has immunological and virological benefits after treatment is stoppedMichael Carter | 10 years ago A short course of antiretroviral therapy during primary HIV infection (PHI) has immunological and v......MORE |
Botswana's ART programme achieves good resultsMichael Carter | 10 years ago Botswana’s antiretroviral treatment (ART) programme has achieved good results, analysis of nine y......MORE |
Implementing viral load testing in resource-limited settings: one size does not fit allMara Kardas-Nelson | 10 years ago Routine viral load can be done in low-resource settings, Helen Bygrave of Médecins Sans Frontière......MORE |
Decentralisation of care reduces HIV and TB-related deaths, illness in Swaziland and UgandaMara Kardas-Nelson | 10 years ago New studies from Eastern and Southern Africa add to mounting evidence that anti-retroviral therap......MORE |
Gilead two-drug hep C combination cures 94% of genotype 1 patients in eight weeksKeith Alcorn | 10 years ago A two-drug combination of sofosbuvir and ledipasvir cured 94% of previously untreated patients with......MORE |
Gilead two-drug hep C combination cures 94% of genotype 1 patients in 8 weeksKeith Alcorn | 10 years ago A two-drug combination of sofosbuvir and ledipasvir cured 94% of previously untreated patients with......MORE |
Health systems, not family factors, most crucial in PMTCT outcomes, Kenyan study showsLesley Odendal | 10 years ago Women who learn of their HIV infection during pregnancy are at higher risk of vertical transmission......MORE |
Widespread support for HIV PrEP among infectious disease doctors in the US and CanadaMichael Carter | 10 years ago Three-quarters of infectious disease specialists in the United States and Canada are supportive of ......MORE |
Starting antiretroviral therapy significantly reduces the risk of decompensated liver disease for men with HIV/HCV co-infectionMichael Carter | 10 years ago Starting antiretroviral therapy (ART) significantly reduces the risk of serious liver disease for p......MORE |
Study provides information on sexual health of male sex workers in EnglandMichael Carter | 10 years ago Male sex workers are significantly more likely to be diagnosed with certain sexually transmitted in......MORE |
HIV treatment in South Africa has had "astounding" benefitsMichael Carter | 10 years ago The roll-out of antiretroviral therapy (ART) in South Africa has achieved “astounding” results,......MORE |
Good adherence to HIV treatment, undetectable viral load, reduce the risk of anal infection with high-risk HPV types for MSM with HIVMichael Carter | 10 years ago Prevalence of anal HPV (human papillomavirus) infection is significantly higher among men with HIV ......MORE |
Men with penile HPV infection have an increased risk of acquiring HIVMichael Carter | 10 years ago Men with penile human papillomavirus (HPV) infection have an increased risk of acquiring HIV, inves......MORE |
NAM prevention survey results: testing underestimated, support for treatment as prevention, reservations about PrEPGus Cairns | 10 years ago A survey of beliefs and opinions on HIV prevention options, conducted by NAM as part of a programme......MORE |
NAM prevention survey: support for treatment as prevention, but reservations about PrEPGus Cairns | 10 years ago A survey of beliefs and opinions on HIV prevention options, conducted by NAM as part of a programme......MORE |
Severity of HIV seroconversion illness associated with subsequent disease progressionMichael Carter | 10 years ago Severity of symptoms during primary HIV infection (PHI) is associated with subsequent disease progr......MORE |
For women, HIV treatment based on atazanavir/ritonavir involves twice the risk of failure compared to efavirenz-containing therapyMichael Carter | 10 years ago Treatment outcomes differ between women taking first-line antiretroviral therapy based on ritonavir......MORE |
Hepatitis C virus dried on inanimate surfaces can remain infectious for up to six weeksMichael Carter | 10 years ago Dried spots of blood contaminated with hepatitis C virus (HCV) can remain infectious for up to six ......MORE |
Major UK study shows rise in HIV testing, but only a quarter of gay men tested in previous yearRoger Pebody | 10 years ago Data from three, large representative samples of the UK population over the last two decades show a......MORE |
Increasing diversity of sexual experience – major UK studyRoger Pebody | 10 years ago There has been significant change in British people’s sexual behaviour and attitudes in recent de......MORE |
Condomless sex increasing in US gay men – especially in HIV-negative and untested menGus Cairns | 10 years ago The proportion of gay men in the US who have had anal sex without a condom at least once in the pas......MORE |
Entecavir + tenofovir works well for people with hepatitis B who have had prior treatment failureLiz Highleyman | 10 years ago A dual regimen of entecavir (Baraclude) plus tenofovir (Viread) for 48 weeks led to virological res......MORE |
Micronutrient supplements delay HIV disease progression for patients with higher CD4 cell countsMichael Carter | 10 years ago Long-term micronutrient supplementation delays HIV disease progression in patients with higher CD4 ......MORE |
Early ART only increases TB IRIS risk for people with HIV who have a CD4 cell count below 50Michael Carter | 10 years ago A low CD4 cell count increases the risk of immune reconstitution inflammatory syndrome (IRIS) for p......MORE |
Faldaprevir effective across patient sub-groups with several baseline characteristics associated with treatment outcomesMichael Carter | 10 years ago The experimental hepatitis C virus (HCV) protease inhibitor is efficacious across a range of subgro......MORE |
After diagnosis of hepatitis C, some gay men willing to consider risk-reduction practicesRoger Pebody | 10 years ago HIV-positive gay men living with HIV in France need better information about the sexual transmissio......MORE |
Proportion of people in southern Africa starting ART with advanced HIV disease fallsMichael Carter | 10 years ago The proportion of people in sub-Saharan Africa who started antiretroviral therapy (ART) with advanc......MORE |
Ritonavir the cause of the interaction between telaprevir and ritonavir-boosted atazanavirMichael Carter | 10 years ago Ritonavir is the cause of the detrimental bi-directional interaction between telaprevir and ritonav......MORE |
Urgent need to address "resurgent" gay global epidemic, says English public health chiefGus Cairns | 10 years ago There is an increasing and potentially catastrophic HIV and sexual health epidemic in gay men and m......MORE |
Partner notification highly effective at finding new HIV cases, but a third who could be tested are missedGus Cairns | 10 years ago Systematically contacting and notifying the sexual partners of people newly diagnosed with HIV is a......MORE |
Faldaprevir safe and effective in HCV treatment-experienced patientsMichael Carter | 10 years ago The investigational hepatitis C virus (HCV) protease inhibitor faldaprevir is a safe and effective ......MORE |
People who aren't taking HIV treatment are a major source of transmitted resistance in Swiss gay menMichael Carter | 10 years ago Individuals who have never taken antiretroviral therapy (ART) are the main source of transmitted HI......MORE |
Largest ever number of HIV diagnoses in UK gay men – due to increased testing and new infectionsRoger Pebody | 10 years ago 3250 gay men were diagnosed with HIV in the United Kingdom during 2012, the largest number of cases......MORE |
Systematic review and meta-analysis shows equivalence of 3TC and FTCMichael Carter | 10 years ago The nucleoside reverse transcriptase inhibitors (NRTIs) 3TC and FTC are equally effective, results ......MORE |
AbbVie reports 96% cure rate for interferon-free hepatitis C regimen in phase 3 studyKeith Alcorn | 10 years ago An interferon-free combination of three drugs plus ribavirin achieved a sustained virologic respons......MORE |
Church attendance associated with late HIV diagnosis among US MSMMichael Carter | 10 years ago Church attendance is associated with late HIV diagnosis among men who have sex with men (MSM), acco......MORE |
Successful hepatitis C treatment reduces risk of liver cancer and death, but most remain untreatedLiz Highleyman | 10 years ago Hepatitis C treatment that leads to viral suppression significantly reduces the likelihood of liver......MORE |
Harm reduction works: extremely low HIV incidence over almost 20 years among people who inject drugs in AustraliaMichael Carter | 10 years ago Incidence of new HIV infections among people who inject drugs in Australia is extremely low, result......MORE |
Sofosbuvir/ribavirin for 24 weeks cures most genotype 3 hepatitis C patients, adding interferon may help difficult-to-treatLiz Highleyman | 10 years ago A dual oral regimen of sofosbuvir plus ribavirin led to sustained response for 93% of genotype 2 he......MORE |
Faldaprevir plus pegylated interferon/ribavirin leads to early sustained response in people with HIV and HCV co-infectionLiz Highleyman | 10 years ago The hepatitis C protease inhibitor faldaprevir plus pegylated interferon and ribavirin improved 4-w......MORE |
Rifampicin dose can be increased safely in TB treatment, may shorten durationMara Kardas-Nelson | 10 years ago Increasing the daily dose of rifampicin within the current TB treatment regimen from 10mg/kg to 15m......MORE |
Audit shows many high HIV prevalence areas in England are failing to expand HIV testingMichael Carter | 10 years ago Most sexual health commissioners for areas in England with a high HIV prevalence have introduced so......MORE |
Daclatasvir + asunaprevir cures 85% of genotype 1b hepatitis C patients in Japanese studyLiz Highleyman | 10 years ago An interferon- and ribavirin-free oral regimen of daclatasvir plus asunaprevir taken for 24 weeks l......MORE |
Fixed-dose sofosbuvir/ledipasvir with or without ribavirin cures most genotype 1 hepatitis C patients, LONESTAR study showsLiz Highleyman | 10 years ago At least 95% of newly treated people with genotype 1 hepatitis C and prior non-responders achieved ......MORE |
Another negative result in the quest for a shorter TB treatment courseMara Kardas-Nelson | 10 years ago Results from a Phase III trial that attempted to shorten the treatment duration for drug-sensitive ......MORE |
Sofosbuvir taken before or after liver transplant reduces hepatitis C recurrenceLiz Highleyman | 10 years ago An interferon-free combination of sofosbuvir plus ribavirin administered before liver transplantati......MORE |
HIV may be becoming less fit as it adapts to the immune systemGus Cairns | 10 years ago HIV, at least in some parts of the world, may be developing a lower replicative capacity as it adap......MORE |
Hepatitis B treatment with entecavir or tenofovir lowers, but does not eliminate, liver cancer riskLiz Highleyman | 10 years ago Long-term treatment with entecavir can reduce the likelihood that people with chronic hepatitis B w......MORE |
Sofosbuvir + ribavirin produces sustained response in 76% of genotype 1 HIV/HCV co-infected peopleLiz Highleyman | 10 years ago An interferon-free regimen of sofosbuvir plus ribavirin taken for 24 weeks cured three quarters of ......MORE |
Simeprevir + sofosbuvir produces high sustained response rates for hard-to-treat patients in COSMOS trialLiz Highleyman | 10 years ago A 12-week all-oral combination of simeprevir plus sofosbuvir led to sustained virological response ......MORE |
BMS interferon-free combination cures over 90% of genotype 1 hepatitis C in 12 weeksKeith Alcorn | 10 years ago A combination of three direct-acting antivirals developed by Bristol-Myers Squibb cured chronic hep......MORE |
Merck interferon-free combination shows high hepatitis C cure rate in early studyKeith Alcorn | 10 years ago A two-drug combination of direct-acting antivirals developed by Merck achieved very high cure rates......MORE |
Need for expansion of hepatitis C screening among veterans, 'baby-boom' generation and pregnant women highlightedKeith Alcorn | 10 years ago Two large studies of the 'baby-boom' generation in the United States suggest that at least 50,000 U......MORE |
AbbVie’s two-drug, interferon-free combination cures genotype 1b hepatitis C infection in 95%Keith Alcorn | 10 years ago A two-drug combination of direct-acting antivirals developed by AbbVie achieved sustained virologic......MORE |
High response rates with telaprevir triple therapy for HIV-positive men with acute hepatitis CLiz Highleyman | 10 years ago Adding telaprevir (Incivo or Incivek) to pegylated interferon and ribavirin shortens the duration o......MORE |
In ELECTRON trial, 100% of hard-to-treat patients cured with sofosbuvir/ledipasvir plus ribavirin or GS-9669Liz Highleyman | 10 years ago Interferon-free regimens of sofosbuvir and ledipasvir plus either ribavirin or GS-9669 taken for 12......MORE |
Urgent need to improve sexually transmitted infection screening for MSM in EuropeRoger Pebody | 10 years ago Across 40 large European cities, less than one third of men who have sex with men (MSM) have been s......MORE |
Gay men who don't have anal sex still at high risk of bacterial STIsMichael Carter | 10 years ago Gay men may still have a significant risk of syphilis and urethral gonorrhoea even if they do not h......MORE |
Once-daily raltegravir effective as maintenance therapyLiz Highleyman | 10 years ago Almost all HIV-positive people with undetectable viral load who switched to once-daily raltegravir ......MORE |
HIV rebound linked to higher baseline level, slower suppression and low-level viraemiaLiz Highleyman | 10 years ago Higher baseline viral load, longer time to viral suppression and low-level viraemia below the level......MORE |
Simultaneous HIV and tuberculosis therapy doesn't cause problems with liver functionMichael Carter | 10 years ago Simultaneous treatment with anti-tuberculosis (TB) drugs and antiretroviral therapy (ART) does not ......MORE |
Dolutegravir matches or surpasses other regimens for first-line HIV treatmentLiz Highleyman | 10 years ago The recently approved HIV integrase inhibitor dolutegravir (Tivicay) provides at least equivalent a......MORE |
HCV reinfection is common among HIV-positive gay men in EuropeLiz Highleyman | 10 years ago Nearly 10% of HIV-positive men acquired hepatitis C virus (HCV) a second time after clearing the vi......MORE |
High prevalence of osteoporosis and osteopenia in young men with HIVMichael Carter | 10 years ago There is an increased prevalence of osteoporosis and osteopenia in young HIV-positive men, Spanish ......MORE |
Low CD4 cell count increases heart attack risk for people with HIVMichael Carter | 10 years ago Immunodeficiency is an important risk factor for heart attack in people living with HIV, results of......MORE |
Social problems and drug and alcohol problems common among people who develop AIDS despite long-term HIV careMichael Carter | 10 years ago Psychiatric, drug, alcohol and social care problems are highly prevalent among people who develop s......MORE |
Social problems and drug and alcohol abuse common among people who develop AIDS despite long-term HIV careMichael Carter | 10 years ago Psychiatric, drug, alcohol and social care problems are highly prevalent among people who develop s......MORE |
Pre-test counselling does not reduce sexual risk reduction – findings support streamlined HIV testing proceduresRoger Pebody | 10 years ago A large randomised controlled trial of rapid HIV testing, with or without risk-reduction counsellin......MORE |
Pre-test counselling does not reduce sexual risk taking – findings support streamlined HIV testing proceduresRoger Pebody | 10 years ago A large randomised controlled trial of rapid HIV testing, with or without risk-reduction counsellin......MORE |
Late testing rates declining in Europe, but largely in gay menGus Cairns | 10 years ago Over Europe as a whole, the proportion of people testing late for HIV decreased between 2002 and 20......MORE |
Considerable increase in unprotected sex found in French/Canadian gay surveyGus Cairns | 10 years ago A French and Canadian online survey of gay men and other men who have sex with men (MSM) appears to......MORE |
Tel Aviv and Bucharest signal warnings of new HIV epidemics among people who inject drugsKeith Alcorn | 10 years ago A switch to a cheaper injectable illicit drug led to a major outbreak of HIV infection in Tel Aviv,......MORE |
Future HIV care will include both novel antiretroviral drugs and new treatment strategiesLiz Highleyman | 10 years ago HIV treatment in the coming years will include novel antiretroviral agents and new formulations suc......MORE |
Faldaprevir demonstrates good early response in genotype 1 HIV/HCV co-infectionLiz Highleyman | 10 years ago The HCV protease inhibitor faldaprevir added to pegylated interferon and ribavirin increased the li......MORE |
Suicide rates tumble in people with HIV in Canadian study but psychiatric drug use remains high in Danish people with HIVGus Cairns | 10 years ago A study presented at the 14th European AIDS Conference last week found that the suicide rate in peo......MORE |
Simeprevir with interferon effective for HIV/HCV co-infected people with genotype 1 hepatitis CLiz Highleyman | 10 years ago Adding the direct-acting hepatitis C drug simeprevir to pegylated interferon and ribavirin produced......MORE |
Dual therapy with Kaletra and 3TC works well regardless of viral loadLiz Highleyman | 10 years ago A dual combination of lopinavir/ritonavir (Kaletra or Aluvia) plus 3TC (lamivudine, Epivir) as firs......MORE |
GSK1265744 rapidly suppresses HIV and appears safe at selected doseLiz Highleyman | 10 years ago The experimental HIV integrase inhibitor GSK1265744 demonstrated rapid and potent antiviral activi......MORE |
Ensuring good-quality HIV care in Europe: where can we improve?Keith Alcorn | 10 years ago Only 20% of people with HIV in Europe have fully suppressed viral load, compared to an estimated 24......MORE |
New EACS treatment guidelines strike balance between individual choice and public health, say writersGus Cairns | 10 years ago A new edition of the European AIDS Clinical Society (EACS) guidelines for the treatment of HIV, HIV......MORE |
New drugs will bring revolution in hepatitis C treatmentLiz Highleyman | 10 years ago The advent of direct-acting antiviral agents can rightly be described as a revolution in treatment ......MORE |
CCR5 inhibitor cenicriviroc shows good activity against HIV; new formulation may reduce dropoutsLiz Highleyman | 10 years ago The dual CCR5/CCR2 inhibitor cenicriviroc demonstrated good antiviral activity and tolerability in ......MORE |
Number of people infected with drug-resistant HIV in Europe has risen by around 35%Keith Alcorn | 10 years ago The number of people in Europe who have become infected with a drug-resistant strain of HIV may hav......MORE |
Anal cancer screening may be appropriate for all women with HIV, French researchers suggestKeith Alcorn | 10 years ago Women living with HIV had a higher risk of anal pre-cancerous changes than cervical changes linked ......MORE |
Experts debate whether HIV cure is 'hype or hope'Liz Highleyman | 10 years ago Is a functional cure for HIV feasible within the foreseeable future or is it a hopeless quest robbi......MORE |
Researchers and advocates discuss biomedical HIV preventionLiz Highleyman | 10 years ago The first day of the 14th European AIDS Conference, which opened yesterday in Brussels, featured a ......MORE |
Researchers and advocates discuss the microbicides pipeline in EuropeLiz Highleyman | 10 years ago The first day of the 14th European AIDS Conference, which opened yesterday in Brussels, featured a ......MORE |
Eastern Europe facing quadruple epidemic while governments do nothing, warns UN Special EnvoyKeith Alcorn | 10 years ago Eastern Europe is facing quadruple, intersecting epidemics of injecting drug use, HIV, tuberculosis......MORE |
Vaccine trials – where next?Gus Cairns | 10 years ago New efficacy trials of HIV vaccines based on what has been learned in the RV144 vaccine trial in Th......MORE |
European physicians condemn impact of Russian anti-gay law on HIV prevention and careKeith Alcorn | 10 years ago The European AIDS Clinical Society (EACS) has strongly condemned the discriminatory legal and polic......MORE |
Big differences in virological outcomes among people taking first-line HIV therapy in resource-limited settingsMichael Carter | 10 years ago Virological outcomes vary enormously among people taking antiretroviral therapy in different resour......MORE |
HIV-positive people not on antiretrovirals are prone to inflammation-related bone lossLiz Highleyman | 10 years ago HIV-positive people not taking antiretroviral therapy experienced more bone mineral density loss at......MORE |
HIV-positive young women have adequate response to human papillomavirus vaccineLiz Highleyman | 10 years ago HIV-positive girls did not respond as well to the quadrivalent human papillomavirus (HPV) vaccine a......MORE |
Only a fifth of pregnancies among women living with HIV in the US are plannedMichael Carter | 10 years ago Only a fifth of pregnancies among women living with HIV in the United States are planned, research ......MORE |
Predicting response to acute hepatitis C treatment in HIV/HCV co-infected peopleLiz Highleyman | 10 years ago HIV/HCV co-infected people with higher HCV viral load, lower CD4 cell counts, older age and unfavou......MORE |
Young people (15 to 24 years) especially likely to drop out of HIV careMichael Carter | 10 years ago Patients aged between 15 and 24 years are significantly more likely to drop out of HIV compared to ......MORE |
Eviplera works well regardless of viral load or CD4 count, may improve lipid levelsLiz Highleyman | 10 years ago The single-tablet regimen Eviplera (rilpivirine/tenofovir/emtricitabine) worked as well as Atripla ......MORE |
Unravelling the mystery of the vaccine trialsGus Cairns | 10 years ago There have been thousands of small vaccine trials in the history of HIV – the first one took plac......MORE |
HIV monitoring every six months is adequate for people on ART with stable viral suppressionLiz Highleyman | 10 years ago People with HIV who have their viral load and CD4 cell count monitored every six months were no mor......MORE |
Specialised testing and social marketing campaigns increase the detection of acute HIV infection among gay menMichael Carter | 10 years ago Big increases in diagnosis rates of acute HIV infection (AHI) can be achieved with the use of targe......MORE |
Daclatasvir works well against hepatitis C either with interferon or in all-oral regimenLiz Highleyman | 10 years ago A short 12- or 16-week triple regimen of daclatasvir plus pegylated interferon/ribavirin cured more......MORE |
Researchers see further positive results with herpes virus-based vaccines in monkeysGus Cairns | 10 years ago One of the biggest news stories at the AIDS Vaccine 2013 conference was the groundbreaking experime......MORE |
Female condom choices are expanding – new models have low failure rates and are acceptable to usersRoger Pebody | 10 years ago A randomised trial has shown that three new models of female condom are non-inferior to the establi......MORE |
The monkeys’ tale – how a vaccine might nip HIV in the budGus Cairns | 10 years ago Four dozen rhesus monkeys may have successfully fought off the monkey equivalent of HIV in a series......MORE |
UK patients with MDR-TB have good outcomes but a quarter not receiving the recommended duration of therapyMichael Carter | 10 years ago Approximately 25% of people with multidrug-resistant tuberculosis (MDR-TB) in the UK are not comple......MORE |
People with HIV have higher risk of death after heart attackLiz Highleyman | 10 years ago People with HIV had higher mortality than HIV-negative individuals after hospitalisation for acute ......MORE |
Does efavirenz use raise the risk of suicide in people with HIV?Liz Highleyman | 10 years ago Suicidal thoughts, attempted suicide and death by suicide were more than twice as common amongst pe......MORE |
HIV vaccine conference opens in most promising research atmosphere for yearsGus Cairns | 10 years ago The 13th – and last – AIDS Vaccine 2013 Conference opened today in Barcelona in an atmosphere o......MORE |
Studies look at community vs hospital-based HIV care and medication issuesLiz Highleyman | 10 years ago HIV-positive people treated at community clinics were more likely to continue receiving care, while......MORE |
Revisiting the safety spectrum: how gay men fall into different 'risk classes' for HIVGus Cairns | 10 years ago Gay men fall into different groups that are at radically different risk for acquiring HIV, Canadian......MORE |
Liver fibrosis linked to immune activation in HIV/HCV co-infected womenLiz Highleyman | 10 years ago CD4 and CD8 cell activation were found to be associated with biomarkers of liver fibrosis among HIV......MORE |
Many HIV-positive people not receiving recommended prevention counselling as part of their routine careMichael Carter | 10 years ago Approximately half of HIV-positive people in the United States are not receiving prevention counsel......MORE |
Long-acting antiretrovirals may improve survival for people with poor adherenceLiz Highleyman | 10 years ago Long-acting antiretroviral formulations taken once-monthly or less have the potential to improve su......MORE |
Liver cancer often diagnosed late with poor survival in people with HIVLiz Highleyman | 10 years ago Hepatocellular carcinoma is frequently diagnosed at an advanced stage in HIV-positive people with h......MORE |
New integrase inhibitor GSK1265744 safe and well tolerated in eight studiesLiz Highleyman | 10 years ago The investigational HIV integrase inhibitor GSK1265744 was well tolerated, with no notable safety c......MORE |
Home-based counselling and testing achieves very high testing rates in KenyaCarole Leach-Lemens | 10 years ago A home-based counselling and testing (HBCT) programme in western Kenya achieved 96% uptake of HIV t......MORE |
Is HCV infection spreading among HIV-positive gay men in Japan?Liz Highleyman | 10 years ago The incidence of acute hepatitis C virus (HCV) co-infection has increased in recent years at the la......MORE |
People's friends diagnose brain impairment better than they do themselvesGus Cairns | 10 years ago Baseline results from a longitudinal study of 235 gay men with HIV aged 18 to 50 attending the Mort......MORE |
Microbicide ring study shows users are reassured about discomfort but develop new worries about safetyGus Cairns | 10 years ago A safety and acceptability study of a vaginal ring containing the antiretroviral drugs dapivirine (......MORE |
Men attending group sex 'slam parties' don’t all use or inject drugsGus Cairns | 10 years ago There has been considerable publicity in the gay, scientific and general media recently about so-ca......MORE |
Cross-sectional study suggests circumcision is having a big impact on HIV rates among men in Orange Farm, South AfricaMichael Carter | 10 years ago Research conducted in South Africa suggests that the roll-out of circumcision is reducing the preva......MORE |
Stribild is effective and well tolerated in older people with HIVLiz Highleyman | 10 years ago The Stribild single-tablet regimen matched both Atripla and boosted atazanavir (Reyataz) in efficac......MORE |
Who will PrEP be for?Gus Cairns | 10 years ago Whether pre-exposure prophylaxis (PrEP) is adopted and is effective as an HIV prevention method dep......MORE |
Infection with HIV associated with increased risk of dialysis and end-stage kidney diseaseMichael Carter | 10 years ago HIV infection increases the risk of kidney disease requiring renal replacement therapy or dialysis,......MORE |
Political leadership on finance and pace of scale-up needed to realise full potential of treatment as preventionKeith Alcorn | 10 years ago Achieving the full potential of antiretroviral treatment as a prevention method will require govern......MORE |
Tenofovir vaginal ring protects monkeys on Depo-Provera against HIV-like virusLiz Highleyman | 10 years ago An intravaginal ring containing tenofovir protected all but one macaque monkey given hormonal contr......MORE |
Uptake of PrEP may be limited because few gay men think they are at risk of HIV infectionRoger Pebody | 10 years ago Three quarters of gay men seeking HIV testing at a Toronto sexual health clinic were assessed as be......MORE |
Treating HCV genotypes 2 and 3 in HIV/HCV co-infected peopleLiz Highleyman | 10 years ago People co-infected with HIV and HCV, mostly with hepatitis C virus (HCV) genotype 3, responded abo......MORE |
Making treatment as prevention a reality for people who inject drugsKeith Alcorn | 10 years ago People who inject drugs risk being left behind as countries make efforts to scale up antiretroviral......MORE |
Single-tablet regimen improves antiretroviral adherence and reduces hospitalisationLiz Highleyman | 10 years ago Antiretroviral treatment that requires only a single tablet taken once daily were associated with b......MORE |
HPV type 39 linked to anal dysplasia, better screening needed for HIV+ men and womenLiz Highleyman | 10 years ago About two-thirds of gay men and one-fifth of women tested in Spain were found to have cell or tissu......MORE |
Economic austerity affects the way in which HIV-positive Londoners view ‘treatment as prevention’Roger Pebody | 10 years ago Discussions of an economic crisis and of austerity contribute to the manner in which people living ......MORE |
Switching from Atripla to Eviplera reduces central nervous system side-effectsLiz Highleyman | 10 years ago People who switched single-tablet regimens from Atripla (efavirenz/tenofovir/emtricitabine) to Evip......MORE |
Late HIV diagnosis continues to be a Europe-wide problemMichael Carter | 10 years ago Late diagnosis of HIV remains a serious problem across Europe, results of a large study published i......MORE |
Interferon response reduces liver disease and death in HIV/HCV co-infected peopleLiz Highleyman | 10 years ago Effective interferon-based therapy that produces sustained virological response led to significant ......MORE |
"If I am given antiretrovirals I will think I am nearing the grave" – a challenge for early treatment strategiesRoger Pebody | 10 years ago Kenyan people living with HIV perceive antiretroviral therapy to be something that is taken in the ......MORE |
Raltegravir appears safe for mothers and babies during pregnancyLiz Highleyman | 10 years ago Antiretroviral regimens containing the integrase inhibitor raltegravir (Isentress) were shown to be......MORE |
Depression linked to episodes of detectable HIV in cerebrospinal fluidLiz Highleyman | 10 years ago People who experience episodes of major depressive disorder (MDD) are significantly more likely to ......MORE |
South American survey finds rectal microbicide formulated as a douche acceptableGus Cairns | 10 years ago A qualitative study of 140 men who have sex with men (MSM) and transgender women (TGW) is three cit......MORE |
Gay men recall seeing mass media campaign, but impact on behaviour remains unclearRoger Pebody | 10 years ago A media campaign promoting condom use and sexual health check-ups to gay and other men who have sex......MORE |
Novel NNRTI AIC292 works well against drug-resistant HIVLiz Highleyman | 10 years ago The next-generation HIV non-nucleoside reverse transcriptase inhibitor (NNRTI) AIC292 showed good a......MORE |
New NNRTI MK-1439 interacts with ritonavir but not tenofovirLiz Highleyman | 10 years ago Blood levels of MK-1439, a next-generation HIV non-nucleoside reverse transcriptase inhibitor (NNRT......MORE |
Dolutegravir shows good efficacy across broad range of patient groupsLiz Highleyman | 10 years ago The new integrase inhibitor dolutegravir worked better than boosted darunavir for people starting H......MORE |
US PrEP prescriptions more likely to go to Southern womenGus Cairns | 10 years ago A US survey of the prescribing of Truvada (tenofovir/emtricitabine) to HIV-negative people as pre-e......MORE |
New tenofovir formulation works equally well with less effect on kidneys and bonesLiz Highleyman | 10 years ago Tenofovir alafenamide (TAF), a new formulation that produces higher drug levels in cells but allows......MORE |
Raltegravir is a good choice for people with HIV undergoing cancer chemotherapyLiz Highleyman | 10 years ago The integrase inhibitor raltegravir (Isentress) may be an optimal choice for many HIV-positive peop......MORE |
CD4 gene therapy may enable functional HIV control during treatment interruptionLiz Highleyman | 10 years ago Two people whose CD4 T-cells were modified to make them resistant to HIV entry experienced substant......MORE |
Hepatitis E virus infection associated with HIV and damage to gut mucosa, Zambian study showsMichael Carter | 10 years ago The prevalence of hepatitis E virus (HEV) infection is strongly associated with HIV status, results......MORE |
Systematic review confirms that regular viral load monitoring assists adherence to HIV therapyMichael Carter | 10 years ago Routine viral load monitoring means that people with treatment adherence problems can be identified......MORE |
Sexual role versatility among HIV-negative US MSM contributing to high level of HIV incidenceMichael Carter | 10 years ago Versatility in anal sex roles is a likely explanation for the continued high rate of new HIV transm......MORE |
Integration of HIV care into primary care reduces deaths in South African trialCarole Leach-Lemens | 10 years ago Integrating HIV care into primary care can improve survival of HIV-positive patients in need of ART......MORE |
Loss of kidney function in older people with HIV underlines need for earlier treatmentMichael Carter | 10 years ago Kidney function deteriorates more rapidly in older people with HIV than in age-matched controls in ......MORE |
Intravenous AZT does not provide extra protection against vertical transmission in mothers with undetectable viral loadCarole Leach-Lemens | 10 years ago Intravenous (IV)-zidovudine (AZT or ZDV) during labour and delivery is effective in reducing mother......MORE |
Text messages do not reduce early resumption of sexual activity in recently circumcised menCarole Leach-Lemens | 10 years ago Text messaging did not help reduce early resumption of sex after male circumcision (MC) in a large ......MORE |
Tenofovir is highly effective for HIV/HBV co-infection, meta-analysis showsLiz Highleyman | 10 years ago Home aidsmap.com Full site Tenofovir is highly effective ......MORE |
Decompensated cirrhosis increases risk of liver cancer for people with HIV and viral hepatitis co-infectionMichael Carter | 10 years ago There is a relatively low incidence of hepatocellular carcinoma (HCC) among people living with HIV ......MORE |
People with HIV/HCV-co-infection and advanced liver fibrosis can rapidly develop decompensated liver diseaseMichael Carter | 10 years ago People living with HIV who have hepatitis C virus (HCV) co-infection and advanced liver fibrosis ca......MORE |
Global AIDS mortality fell by over 20% in last five years, but large inequalities remain between countriesGus Cairns | 10 years ago The overall annual death rate from AIDS has fallen by 21% since 2006, the most recent study in the ......MORE |
Persisently detectable viral load at any level increases risk of HIV treatment failureMichael Carter | 10 years ago For people taking HIV therapy, a persistent detectable viral load at any level is associated with a......MORE |
High rates of anal HPV infection among young gay menMichael Carter | 10 years ago Prevalence and incidence of anal human papillomavirus (HPV) are high among young gay men, according......MORE |
Partner violence may undermine use of female-controlled forms of HIV preventionMichael Carter | 10 years ago Women who experience violence from their male partner are less likely to use condoms or diaphragms,......MORE |
A fifth of gay men in a relationship with an HIV-negative man have not tested for HIV while in their current relationshipMichael Carter | 10 years ago A fifth of gay men in a relationship with an HIV-negative male partner have not had an HIV test whi......MORE |
Kenyan sex workers and men who have sex with men find PrEP acceptable but worry about others' assumptionsGus Cairns | 10 years ago Qualitative interviews from an already published placebo-controlled study of 66 men who have sex wi......MORE |
High proportion of Canadian patients with HIV-HCV co-infection and liver cirrhosis are not having ultrasounds to check for liver cancerMichael Carter | 10 years ago Over a third of HIV-positive people with hepatitis C virus-related liver cirrhosis are not having r......MORE |
Low baseline CD4 cell count associated with greater bone loss after starting HIV therapyMichael Carter | 10 years ago A low baseline CD4 cell count is associated with loss of bone mineral density (BMD) during the earl......MORE |
Cleared HCV infection associated with increased risk of kidney disease in people with HIVMichael Carter | 10 years ago People living with HIV with previous hepatitis C virus (HCV) infection continue to have an increase......MORE |
High prevalence of CMV retinitis among HIV-positive patients in Asia and AfricaMichael Carter | 10 years ago Prevalence of CMV retinitis remains high among HIV-positive patients in resource-limited settings, ......MORE |
Considerable increase in unprotected sex found in French gay surveyGus Cairns | 10 years ago A French and Canadian online survey of gay men and other men who have sex with men (MSM) appears to......MORE |
Legal barrier to self-testing for HIV in UK to be liftedKeith Alcorn | 10 years ago The Department of Health announced an important change to HIV testing policy for the United Kingdom......MORE |
UK health care workers with HIV to be cleared for dental and surgical workKeith Alcorn | 10 years ago Health care workers in the United Kingdom living with HIV will be permitted to carry out exposure-p......MORE |
UK healthcare workers with HIV to be cleared for dental and surgical workKeith Alcorn | 10 years ago Healthcare workers in the United Kingdom living with HIV will be permitted to carry out exposure-pr......MORE |
Pegylated interferon with antiretroviral therapy achieves promising results in patients with difficult-to-treat Kaposi's sarcomaMichael Carter | 10 years ago Pegylated interferon alfa-2a (PegIFN) may be an effective therapy for Kaposi's sarcoma (KS) that ha......MORE |
High prevalence of heart rhythm disturbance among HIV-positive people on methadone maintenance therapyMichael Carter | 10 years ago Spanish investigators have identified a high prevalence of a potentially life-threatening disturban......MORE |
CD4 cell count at time of entry to HIV care did not increase significantly between 1992 and 2011Michael Carter | 10 years ago The average CD4 cell count of people newly entering HIV care in resource-rich countries did not inc......MORE |
Few AIDS diagnoses among people with higher CD4 cell counts, but risk remains elevated for those with a count below 750Michael Carter | 10 years ago Incidence of AIDS-defining illnesses remains elevated even when the CD4 cell count is between 500 a......MORE |
Immune suppression and smoking history are risks for HPV-related anal disease in HIV-positive gay menMichael Carter | 10 years ago Risk factors for human papillomavirus (HPV)-associated anal disease in HIV-positive gay men are sim......MORE |
Community study finds no evidence of widespread HCV epidemic among HIV-negative gay men in LondonMichael Carter | 10 years ago Approximately 1% of HIV-negative gay men in London had antibodies to the hepatitis C virus (HCV) in......MORE |
A quarter of HIV/HCV-co-infected people in EuroSIDA have received HCV therapyMichael Carter | 10 years ago A quarter of HIV-positive people in the EuroSIDA cohort with chronic hepatitis C virus (HCV) co-inf......MORE |
Evidence is not yet sufficient to recommend universal treatment, clinicians and community writers sayGus Cairns | 10 years ago We do not yet have sufficiently strong evidence to recommend that antiretroviral treatment (ART) sh......MORE |
HIV treatment has not led to increasing sexual risk-taking in rural South African communitiesGus Cairns | 10 years ago A study from a rural area in the province of KwaZulu Natal, South Africa, has found no evidence tha......MORE |
Opportunities being missed for a vaginal delivery for HIV-positive pregnant women in Europe with viral suppressionMichael Carter | 10 years ago There are “missed opportunities” for HIV-positive pregnant women with a suppressed viral load t......MORE |
Smoking cannabis does not accelerate progression of liver disease in people with HIV/HCV co-infectionMichael Carter | 10 years ago Smoking cannabis does not worsen liver disease in people with HIV and hepatitis C virus (HCV) co-in......MORE |
Drinking alcohol doesn't increase the risk of HIV treatment failureMichael Carter | 10 years ago Alcohol consumption has little impact on key markers used to monitor the health of individuals with......MORE |
Investigators identify genetic profile associated with better treatment outcomes in people with HIV/HCV co-infectionMichael Carter | 10 years ago Several genetic characteristics are associated with a successful response to treatment for hepatiti......MORE |
Lymphoma mortality rates remain elevated among HIV-positive people in the United StatesMichael Carter | 10 years ago HIV-positive people in the United States diagnosed with certain types of lymphoma continue to have ......MORE |
Biomedical HIV prevention – the social complexities of achieving effectivenessRoger Pebody | 10 years ago Public health officials, donors, epidemiologists, researchers and clinicians need to factor in the ......MORE |
Only a weak association between immune suppression and increased cardiovascular disease risk for people with HIVMichael Carter | 10 years ago There is only a weak association between immune suppression and risk of heart attack and coronary h......MORE |
Number of patients diagnosed with HCV in England increased by a third between 2010 and 2012Michael Carter | 10 years ago The UK is making progress in the prevention, diagnosis and treatment of hepatitis C virus (HCV), a ......MORE |
"Strong" argument for providing HPV vaccination to younger gay men in the UKMichael Carter | 10 years ago There is a “strong” argument for extending UK HPV (human papillomavirus) vaccination programmes......MORE |
Gay men diagnosed with a rectal STI have a very high risk of subsequent infection with HIVMichael Carter | 10 years ago The rate of new HIV infections is especially high among gay men recently diagnosed with a rectal se......MORE |
HIV/HCV co-infected people can do well on hepatitis C triple therapy despite contraindicationsLiz Highleyman | 10 years ago Nearly three-quarters of HIV/HCV co-infected patients in the French HEPAVIH cohort achieved end-of-......MORE |
What HIV self-testing may mean for couplesLaura Lopez Gonzalez | 10 years ago A study in Malawi is offering glimpses into why couples opt for HIV self-testing – including issu......MORE |
Women with HIV feel 'under surveillance' during pregnancy and early motherhoodRoger Pebody | 10 years ago Women living with HIV are subject to questioning, monitoring and surveillance of their choices duri......MORE |
Many gay men enjoy bareback porn, but are concerned about its possible effects on sexual behaviourRoger Pebody | 10 years ago Many gay men who watch pornography enjoy and sometimes prefer material in which condoms are not use......MORE |
Medical male circumcision campaigns face cultural challenges in southern AfricaLaura Lopez Gonzalez | 10 years ago Campaigns to circumcise tens of thousands of men in southern Africa are falling victim to lingering......MORE |
Genetic testing lowers risk of nevirapine skin rashLiz Highleyman | 10 years ago Screening for genetic mutations could substantially reduce the risk of hypersensitivity reactions i......MORE |
Vaccination could prevent infection with anal cancer-associated HPV strains in older gay menMichael Carter | 10 years ago A large number of infections with anal cancer-associated strains of human papillomavirus (HPV) amon......MORE |
Male circumcision: the message is catching on, but scale-up poses monitoring and follow-up problemsGus Cairns | 10 years ago Programmes offering voluntary medical male circumcision (VMMC) as part of HIV prevention are now st......MORE |
Six in ten European gay men have had unprotected sex in the past year – more common with steady partnersRoger Pebody | 10 years ago Across Europe, 58% of gay and other men who have sex with men (MSM) report at least one incident of......MORE |
South African couples living with HIV are missing out on safer conception adviceLaura Lopez Gonzalez | 10 years ago Clinicians and counsellors may understand the right of people living with HIV to have children, but......MORE |
Text messages to mothers improve early infant HIV diagnosis rates in Kenya and MozambiqueCarole Leach-Lemens | 10 years ago Use of text messaging significantly improved the rate of early infant diagnosis (EID) among HIV-pos......MORE |
'Option B+' women are at increased risk of loss to follow-up after starting HIV treatmentLesley Odendal | 10 years ago Women who begin HIV treatment during pregnancy, or while breastfeeding, prior to the CD4 cell thres......MORE |
Kidney problems linked to tenofovir use, improve with switch to abacavirLiz Highleyman | 10 years ago Indian people with HIV taking tenofovir had a higher rate of kidney impairment than westerners, acc......MORE |
Stigma, delay and misunderstanding slow access to ART in AfricaGus Cairns | 10 years ago Three presentations at the recent 7th International AIDS Society conference on HIV Pathogenesis, T......MORE |
Scientists and clinicians must challenge HIV-related stigma and ensure enabling legal and policy environments, IAS conference hearsEdwin J. Bernard | 10 years ago Scientists should not only create knowledge to improve the HIV epidemic, they also have a duty to s......MORE |
Efavirenz in children: WHO dosing guidelines raise the risk of side-effects in Thai childrenCarole Leach-Lemens | 10 years ago Taking efavirenz according to 2010 World Health Organization (WHO) guidelines ensures a higher prop......MORE |
Non-African middle-income countries pay four times more for ARVs than African middle-income countriesLesley Odendal | 10 years ago Middle-income countries outside Africa are paying, on average, four times more for antiretrovirals ......MORE |
Darunavir/ritonavir safe and effective for younger childrenCarole Leach-Lemens | 10 years ago Over 80% of treatment-experienced children with HIV aged three to six years from ten sites in Argen......MORE |
Lower-dose lopinavir/ritonavir reduces side-effects, maintains viral control in Thai childrenCarole Leach-Lemens | 10 years ago Low dose lopinavir/ritonavir (LPV/r) – 70% of the standard dose – worked as well as standard do......MORE |
Magical thinking? FEM-PrEP trial may have failed because participants used testing as preventionGus Cairns | 10 years ago While the 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (......MORE |
Malaysia’s harm reduction programmes are preventing infections and saving money, but reaching far too few people who inject drugsRoger Pebody | 10 years ago An expansion of methadone maintenance and needle exchange programmes in Malaysia, a conservative Mu......MORE |
Fibroscan accurately predicts liver decompensation and death in HIV/HCV co-infected peopleLiz Highleyman | 10 years ago The non-invasive transient elastometry method of estimating liver damage may be a better way to pre......MORE |
Studies look at bone changes during second-line therapy, fractures, and HIV- and HCV-related bone lossLiz Highleyman | 10 years ago People with HIV experience less bone loss if they switch to a NRTI-sparing second-line regimen cont......MORE |
Strategies to detect and treat MSM with acute infection may be a powerful tool to control HIV epidemicsRoger Pebody | 10 years ago The detection and control of acute (very recent) HIV infection may be a powerful HIV prevention mea......MORE |
Long-acting GSK1265744 and TMC278-LA appear safe and practical in early studyLiz Highleyman | 10 years ago A combination of antiretroviral drugs in long-acting nanosuspension formulations achieved adequate ......MORE |
No increase in risk behaviour in people taking antiretroviral therapy, meta-analysis showsRoger Pebody | 10 years ago One of the anxieties in relation to ‘treatment as prevention’ is that it may discourage people ......MORE |
First-line antiretroviral therapy has improved over time, meta-analysis showsLiz Highleyman | 10 years ago The effectiveness of initial antiretroviral treatment has improved markedly over the years, but man......MORE |
Intervention with cash lottery prizes cuts HIV infection by 39% in young women in LesothoRoger Pebody | 10 years ago An HIV prevention intervention in which young people who had tested negative for sexually transmitt......MORE |
Ambitious plans for treatment as prevention in Asia, but challenges remainRoger Pebody | 10 years ago Countries such as China, Cambodia and Vietnam have made strong commitments to curbing their HIV epi......MORE |
Dolutegravir superior to raltegravir for treatment-experienced people with HIVLiz Highleyman | 10 years ago The once-daily HIV integrase inhibitor dolutegravir demonstrated better efficacy than twice-daily r......MORE |
Reduced efavirenz dose suppresses HIV as well as standard doseLiz Highleyman | 10 years ago Lowering the dosage of efavirenz (Sustiva or Stocrin) from 600 to 400mg in an antiretroviral regime......MORE |
Study supports WHO recommendations for second-line HIV therapy in resource-limited countriesLiz Highleyman | 10 years ago A second-line regimen consisting of a protease inhibitor (PI) plus two nucleoside/nucleotide revers......MORE |
Bangkok PrEP study finds PrEP efficacy is related to drug exposureGus Cairns | 10 years ago The 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention heard ......MORE |
PrEP appears safe for use in conception, but may not be necessary if partner is taking treatmentRoger Pebody | 10 years ago HIV-negative women who wish to become pregnant with their male HIV-positive partner can be reassure......MORE |
First-ever community-randomised combination prevention trial produces modest drop in HIV incidence, big increase in testing in menGus Cairns | 10 years ago The results of a pioneering HIV prevention trial comparing the effects of mobile HIV testing, commu......MORE |
Two stem cell transplant recipients now controlling HIV off treatmentKeith Alcorn | 10 years ago Two people with HIV who received stem cell transplants for the treatment of lymphoma are now contro......MORE |
How can most-at-risk populations be encouraged to seek HIV testing?Lesley Odendal | 10 years ago Peer-mediated HIV counselling resulted in the highest uptake of HIV counselling and testing (HCT) a......MORE |
Kick, kill, contain – researchers examine three possible steps in a cure for HIVGus Cairns | 10 years ago The 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS ......MORE |
Starting treatment at a CD4 count above 500 reduces the HIV reservoir for people with long-term infectionKeith Alcorn | 10 years ago People with HIV who start treatment with CD4 counts above 500, after the first phase of primary inf......MORE |
Home visits during pregnancy increase number of male partners tested for HIVRoger Pebody | 10 years ago A randomised controlled trial in Kenya has found that home visits immediately after a woman’s app......MORE |
German researchers report case of 'functional cure' after very early HIV treatmentKeith Alcorn | 10 years ago Another case of prolonged control of HIV replication after stopping treatment was reported on Tuesd......MORE |
AbbVie interferon-free hepatitis C combo works well with reduced ribavirin doseLiz Highleyman | 10 years ago People taking hepatitis C treatment who reduced their dose of ribavirin due to side-effects neverth......MORE |
Experts discuss role of drug policy in HIV, hepatitis and TB epidemicsLiz Highleyman | 10 years ago International drug policy must shift from prohibition to public health in order to reduce harms to ......MORE |
High linkage to care after community-based HIV counselling and testing in South Africa associated with confidence in drug supplies, depressionLesley Odendal | 10 years ago Believing that drugs and supplies are generally available at the local health facility and experien......MORE |
Hepatitis C reinfection occurs frequently among gay men living with HIV in LondonMichael Carter | 10 years ago There is a high incidence of hepatitis C virus (HCV) reinfection among gay men living with HIV in L......MORE |
New recommendations on HIV treatment for children require earlier diagnosis, new drug combinations for maximum impactKeith Alcorn | 10 years ago New World Health Organization (WHO) guidelines recommending antiretroviral treatment for all childr......MORE |
Turning surveillance into support for men who have sex with men in AfricaGus Cairns | 10 years ago We need to stop simply doing research into the health and behaviours of gay men and other men who h......MORE |
High positivity rate and good linkage to care at Barcelona community testing projectRoger Pebody | 10 years ago A single community testing site is testing over a third of the gay men newly diagnosed with HIV in......MORE |
Management of age-related conditions is 'the future of HIV care', says IAS conference keynote speakerLiz Highleyman | 10 years ago Other diseases are becoming far more important than AIDS for people with HIV who have consistent ac......MORE |
Cure research is new phase of HIV therapy, says US AIDS chiefKeith Alcorn | 10 years ago “We are at the earliest dawn of a new stage of HIV therapy” said Carl Dieffenbach, director of ......MORE |
WHO issues new HIV recommendations calling for earlier ARV initiationLesley Odendal | 10 years ago New HIV treatment guidelines by the World Health Organization (WHO) launched today at the 7th Inte......MORE |
People with HIV outside continuous care contribute disproportionately to viral load and infection potential, Canadian study findsGus Cairns | 10 years ago A study from Calgary in Canada has found that people who were in continuous care for a year, althou......MORE |
Fear of future health problems encourage people to start and complete HCV therapy but concern about side-effects is a deterrentMichael Carter | 10 years ago US research has provided important insights into the factors that motivate and deter people from st......MORE |
Knowledge gaps, problems accessing services for MSM in several countries of eastern and south-eastern EuropeRoger Pebody | 10 years ago A substantial minority of men who have sex with men (MSM) in countries such as Cyprus, Serbia, Lith......MORE |
Kaletra monotherapy achieves 'satisfactory' levels of HIV suppression during pregnancyMichael Carter | 10 years ago Kaletra (lopinavir/ritonavir) monotherapy achieves satisfactory levels of virological suppression i......MORE |
Home-based counselling and testing with point-of-care CD4 counts maximises linkage to care in rural South AfricaCarole Leach-Lemens | 10 years ago Home-based testing and counselling (HBCT), combined with same day point-of-care CD4 testing and lay......MORE |
European gay men more likely to buy or sell sex if they have large numbers of sex partners, are lonely and use drugsMichael Carter | 10 years ago Results of a large European internet-based survey show that 8% of gay and other men who have sex wi......MORE |
Antiretroviral therapy cuts mortality risk for people diagnosed with HIV-related lymphomaMichael Carter | 10 years ago Higher cumulative viral load in the six months after diagnosis with HIV-related lymphoma is associa......MORE |
Sex while abroad contributing to ongoing HIV and STI epidemics in European gay menMichael Carter | 10 years ago Sex while abroad appears to be contributing to the ongoing epidemics of HIV and other sexually tran......MORE |
Elevated prevalence of HIV and STIs among migrant gay men in EuropeMichael Carter | 10 years ago Migrant gay and other men who have sex with men (MSM) have a higher prevalence of HIV and sexually ......MORE |
New prevention strategies will only be implemented if they are tailored to local contexts and culturesRoger Pebody | 10 years ago While clinical trials have demonstrated the efficacy of treatment as prevention, pre-exposure proph......MORE |
ARV and TB medicine drug supply issues threaten South Africa’s ARV programmeLesley Odendal | 10 years ago HIV activist groups in South Africa are calling on the Minister of Health to address drug supply c......MORE |
Interaction between steroid injections and HIV protease inhibitors can disrupt cortisol levelsMichael Carter | 10 years ago Corticosteroid injections can lead to dysfunctions in cortisol levels in people taking HIV protease......MORE |
Prompt HIV diagnosis and early antiretroviral therapy especially important for older peopleMichael Carter | 10 years ago Prompt HIV diagnosis and early antiretroviral therapy are especially important for older people, re......MORE |
Over half of people living with AIDS in San Francisco are aged 50 or olderMichael Carter | 10 years ago Over half of people living with an AIDS diagnosis in San Francisco are aged 50 or older, investigat......MORE |
Hyaluronic acid levels can predict risk of serious liver events in people living with HIV and hepatitis B or C co-infectionMichael Carter | 10 years ago A simple blood test can predict the risk of liver-related death or hepatic encephalopathy for peopl......MORE |
PrEP works for injecting drug users tooRoger Pebody | 10 years ago A daily tablet of tenofovir, a drug otherwise used to treat HIV infection, reduced the risk of HIV ......MORE |
Sexual health information is often inappropriate for Facebook sharing, say young peopleRoger Pebody | 10 years ago Sexual health promoters who wish to harness the power of Facebook and other social media need to co......MORE |
Low CD4 cell count increases the risk of several cancers after starting HIV therapyMichael Carter | 10 years ago A large US study has provided important new insights into the incidence and timing of cancers among......MORE |
Mobile phone support increases chances that people living with HIV will quit smokingMichael Carter | 10 years ago Smoking cessation support delivered via mobile phones increases chances that people living with HIV......MORE |
Undetectable viral load reduces the risk of HIV-associated anal cancerMichael Carter | 10 years ago HIV therapy that effectively controls viral load reduces the risk of anal cancer, US research publi......MORE |
High rate of spontaneous disease regression in men with high-grade pre-cancerous anal lesionsMichael Carter | 10 years ago High-grade pre-cancerous anal lesions are more likely to regress than progress, according to Austra......MORE |
Intimate partner violence associated with subsequent HIV infection in UgandaRoger Pebody | 10 years ago Ugandan women who have been subject to violence from a sexual partner are more likely than other wo......MORE |
Combination prevention could "eliminate" HIV transmissions in Vietnam, model projectsMichael Carter | 10 years ago A “combination prevention” strategy with targeted HIV testing and early antiretroviral therapy ......MORE |
Female sex workers frequently offered larger fees by their clients in return for sex without a condomMichael Carter | 10 years ago Client demand for unprotected sex is contributing to the HIV epidemic among female sex workers, acc......MORE |
High rates of gonorrhoea among people living with HIV in the USMichael Carter | 10 years ago Combining HIV and gonorrhoea surveillance databases has revealed a high prevalence of gonorrhoea am......MORE |
2012: half a million sexually transmitted infections in EnglandRoger Pebody | 10 years ago There were just under half a million new diagnoses of sexually transmitted infections (STIs) in 201......MORE |
People doing well on HIV therapy have a mortality risk identical to that of HIV-negative peersMichael Carter | 10 years ago HIV-positive people taking antiretroviral therapy who have an undetectable viral load and a CD4 cel......MORE |
Campaign approach increases enrolment of pregnant women on ART in South AfricaKeith Alcorn | 10 years ago A targeted campaign among health workers, using quality-improvement (QI) health system methods, can......MORE |
Campaign approach increases enrolment of pregnant women on ART in South AfricaCarole Leach-Lemens | 10 years ago A targeted campaign among health workers, using quality-improvement (QI) health system methods, can......MORE |
Nevirapine dose escalation for children may risk treatment failureCarole Leach-Lemens | 10 years ago Full-dose nevirapine should be considered for HIV-positive children under two years of age in Afric......MORE |
Community viral load is flawed indicator of infectiousness, say expertsGus Cairns | 10 years ago Four US researchers from the University of Chapel Hill in North Carolina, including Myron Cohen, pr......MORE |
HIV cure: the long road aheadKeith Alcorn | 10 years ago Scientists from around the world met to review the future of HIV scientific research at the Institu......MORE |
'War on drugs' fuelling the hepatitis C epidemic among people who inject drugsMichael Carter | 10 years ago The global war on drugs has had a disastrous impact on the hepatitis C epidemic, a new report from ......MORE |
Deciding what’s risky – Australian gay men pay more attention to the sexual act than to their partner’s HIV status or viral loadRoger Pebody | 10 years ago HIV-negative gay men in Sydney, Australia perceive the risk of HIV transmission to be different in ......MORE |
Hepatitis C treatment gap in Europe: France doing well but Italy treated fewer than one in a hundred patients in 2010Keith Alcorn | 10 years ago France led the world in the proportion of its hepatitis C patients who received treatment in 2010, ......MORE |
Small fall in new HIV diagnoses in London, but rate of new diagnoses among gay men continues to increaseMichael Carter | 10 years ago There was a modest fall in the number of new HIV diagnoses in London in 2011, new figures show. A t......MORE |
Expanded access to HIV treatment achieves big falls in mortality rates in ChinaMichael Carter | 10 years ago Mortality rates fell sharply among people receiving antiretroviral therapy in China between 2003 an......MORE |
AZT associated with poorer immunological recovery in people taking first-line HIV treatment in southern AfricaMichael Carter | 10 years ago AZT-based antiretroviral therapy is associated with lower increases in CD4 cell counts than other H......MORE |
Majority of Italian HIV specialists would prescribe PrEPGus Cairns | 10 years ago Seventy per cent of Italian HIV specialists who answered an online survey would prescribe pre-expos......MORE |
Case workers can re-engage a high proportion of HIV-positive people lost to long-term careMichael Carter | 10 years ago Caseworkers helped 50% of HIV-positive people in New York City who had dropped out of care re-engag......MORE |
Higher rates of HIV in US black gay men may be due to smaller choice of partners and more age mixingGus Cairns | 10 years ago Limited partner choice, wider age gaps between partners, and mistaken beliefs about HIV status in r......MORE |
Dramatic improvements in HIV testing are possible – local leadership and multiple initiatives requiredRoger Pebody | 10 years ago In Brighton & Hove the proportion of new HIV diagnoses which are made outside of sexual health and ......MORE |
Triple therapy for hepatitis C is effective after liver transplantation, but side-effects are commonLiz Highleyman | 10 years ago Adding the approved HCV protease inhibitor telaprevir (Incivo or Incivek) to pegylated interferon ......MORE |
Engagement with health care leads to more prompt HIV diagnosis and higher rates of virological suppression among gay menMichael Carter | 10 years ago Pre-existing connection with primary health care is associated with more prompt diagnosis of HIV in......MORE |
Hepatitis E virus infection can cause rapid liver cirrhosis in people with HIV who have low CD4 cell countsMichael Carter | 10 years ago Infection with hepatitis E virus (HEV) can cause rapid liver fibrosis in people with HIV who have l......MORE |
More drugs, more alcohol often means more risky sex for HIV-negative gay menMichael Carter | 10 years ago There is a highly significant relationship between frequency and intensity of drug and alcohol use ......MORE |
People more likely to keep HIV clinic appointments if they believe their care providers know them as a personMichael Carter | 10 years ago People who believe their care providers know them as a person are more likely to keep their HIV cli......MORE |
New HCV combinations could have a big role in prevention, but only if treatment rates increaseMichael Carter | 10 years ago New combinations of hepatitis C drugs could have major public health benefits, a modelling study pu......MORE |
Up to a third of HIV infections in European gay men may have come from another countryGus Cairns | 10 years ago A study (Frentz) that looked at genetic similarities in the HIV from recently diagnosed people in 2......MORE |
Movement for global access to hepatitis C treatment building momentumKeith Alcorn | 10 years ago Access to hepatitis C treatment in low- and middle-income countries is being restricted by the hig......MORE |
Herpes viruses associated with shedding of HIV in the semen of gay men taking suppressive antiretroviral therapyMichael Carter | 10 years ago Low level HIV replication in semen persists in almost 10% of gay men taking antiretroviral therapy,......MORE |
Report highlights major failings in UK response to hepatitis CMichael Carter | 10 years ago The UK needs to “be doing so much more” in response to hepatitis C, according to a new report. ......MORE |
High prevalence of oral HPV infection in Dutch gay menMichael Carter | 10 years ago Oral infection with human papillomavirus (HPV) is common among gay men, Dutch investigators report ......MORE |
Daclatasvir + asunaprevir + BMS-791352 looks promising as interferon-free combinationLiz Highleyman | 10 years ago An all-oral regimen containing three next-generation antivirals taken for either 12 or 24 weeks pro......MORE |
Blackmail, violence and stigma restrict access to sexual health services for gay men, Global Health and Rights Study reportsGus Cairns | 10 years ago The Global Forum for MSM and HIV has released an analysis of its 2012 Global Men’s Health and Rig......MORE |
Compassionate access to new hepatitis C drugs an "emergency" for European patientsKeith Alcorn | 10 years ago European governments must move quickly to ensure that compassionate use arrangements are put into p......MORE |
Second-generation protease inhibitor faldaprevir cures up to 80% of hepatitis CKeith Alcorn | 10 years ago A second-generation hepatitis C protease inhibitor, faldaprevir, cured up to 80% of previously untr......MORE |
Second-generation HCV protease inhibitor simeprevir pushes triple therapy cure rate up to 80%Keith Alcorn | 10 years ago A second-generation hepatitis C protease inhibitor, simeprevir, cured around 80% of previously untr......MORE |
Triple-drug HCV therapy comes with high risk of serious adverse events for people with cirrhosisKeith Alcorn | 10 years ago Currently available triple therapies for hepatitis C carry a high risk of serious side-effects for ......MORE |
Hep C quad regimens quashed, but some components go forwardLiz Highleyman | 10 years ago A pair of four-drug interferon-based hepatitis C regimens worked well, but further study has been h......MORE |
Daclatasvir + sofosbuvir offers hepatitis C rescue therapy after current standard of careLiz Highleyman | 10 years ago An interferon-free regimen of daclatasvir plus sofosbuvir, with or without ribavirin, cured all pre......MORE |
A majority of HIV-positive gay men in Dutch survey take their viral load into consideration if having unprotected sexGus Cairns | 10 years ago About 40% of men who answered a community survey for HIV-positive gay men in the Netherlands said t......MORE |
Researchers stop the only current HIV vaccine efficacy trialGus Cairns | 11 years ago The US National Institute of Allergy and Infectious Diseases (NIAID) has announced that it is disco......MORE |
AbbVie interferon-free combination cures over 90% of hepatitis C genotype 1Keith Alcorn | 11 years ago A four-drug combination of direct acting antivirals developed by AbbVie cured hepatitis C infection......MORE |
Sofosbuvir + ribavirin cures most genotype 2 hepatitis C, but genotype 3 response is lowerLiz Highleyman | 11 years ago A dual oral regimen containing the hepatitis C nucleotide polymerase inhibitor sofosbuvir plus rib......MORE |
Consistent decline in partner numbers in US gay men in last decade, but no change in condom useGus Cairns | 11 years ago Data from two national sex surveys in the United States show that gay and bisexual men (men who hav......MORE |
Genetics make a large contribution to cardiovascular risk for people with HIVMichael Carter | 11 years ago Genetic background has a major impact on the risk of coronary artery disease for people with HIV, r......MORE |
For African women in the UK, formula feeding has a high social and personal costRoger Pebody | 11 years ago Although most African women living with HIV in the UK do comply with medical recommendations to avo......MORE |
Some barriers to adherence for black African people in London are culturally specificRoger Pebody | 11 years ago Qualitative research suggests that some of the barriers to antiretroviral adherence for black Afric......MORE |
London HIV drug prescribing changes – patient satisfaction and clinical outcomes maintainedRoger Pebody | 11 years ago Controversial changes to the range of anti-HIV drugs which are most commonly prescribed in London h......MORE |
Training for GPs can increase HIV testing rateRoger Pebody | 11 years ago A multifaceted educational intervention for doctors and practice nurses working in general practice......MORE |
Elevated prevalence of HIV and viral hepatitis in men injecting anabolic steroidsRoger Pebody | 11 years ago Addressing a topic that has received remarkably little research attention over the years, Dr Vivian......MORE |
England: Health & Wellbeing Boards not prioritising HIVRoger Pebody | 11 years ago In areas of high HIV prevalence in England, half the local authorities have not made HIV a public h......MORE |
England: health and wellbeing boards not prioritising HIVRoger Pebody | 11 years ago In areas of high HIV prevalence in England, half the local authorities have not made HIV a public h......MORE |
Integrating HIV care into community health workers' role is a good model for southern AfricaCarole Leach-Lemens | 11 years ago A community health worker model of home-based preventive care, the Philani Intervention Program (PI......MORE |
South African clinics already achieving zero new HIV infections in childrenCarole Leach-Lemens | 11 years ago Maternity clinics in South Africa have the potential to achieve zero transmission of HIV from mothe......MORE |
South African clinics already achieving zero new HIV infections in childrenKeith Alcorn | 11 years ago Maternity clinics in South Africa have the potential to achieve zero transmission of HIV from mothe......MORE |
Liver disease a major cause of illness and death across the EU: action needed to save livesMichael Carter | 11 years ago Liver disease is the cause of a considerable burden of illness across the European Union (EU), inve......MORE |
Life expectancy for South African patients who start HIV therapy with CD4 cell counts above 200 is 'near normal'Michael Carter | 11 years ago HIV-positive patients in South Africa can have a near-normal life expectancy, provided that they st......MORE |
PrEP doesn't lead to increases in risky sex among gay menMichael Carter | 11 years ago Taking HIV pre-exposure prophylaxis (PrEP) does not lead to increased levels of sexual risk behavio......MORE |
CMV replication associated with increased mortality risk in Thai patients starting HIV therapyMichael Carter | 11 years ago Ongoing cytomegalovirus (CMV) replication is associated with an increased mortality risk for people......MORE |
Treating everyone diagnosed would not end HIV in US gay men, Los Angeles-based model findsGus Cairns | 11 years ago Increasing HIV testing frequency, and giving everyone antiretroviral therapy (ART), would not in th......MORE |
Viral load in genital secretions differs between men and women undergoing HIV therapyMichael Carter | 11 years ago The female genital tract appears to be a 'reservoir' for ongoing HIV replication, even during effec......MORE |
No increase in sexual risk taking by gay men in England, 2001 to 2008Roger Pebody | 11 years ago Analysis of Gay Men’s Sex Survey data shows that, overall, the proportion of men reporting unprot......MORE |
Hepatitis C epidemic in US gay men is decades oldMichael Carter | 11 years ago Hepatitis C virus (HCV) transmissions have been occurring in gay men since at least the early years......MORE |
One-in-four deaths in pregnancy due to HIV in worst-affected countriesCarole Leach-Lemens | 11 years ago One-in-four pregnancy-related deaths is due to HIV in countries with a high HIV prevalence, a meta-......MORE |
Marriage is a risk factor for HIV infection in MalawiRoger Pebody | 11 years ago Marriages in Malawi are characterised by such stark gender inequalities that marriage itself is a r......MORE |
Disagreements about agreements – many gay couples lack clarity on sex outside their relationshipRoger Pebody | 11 years ago The majority of American gay men in relationships say they establish a ‘sexual agreement’ with ......MORE |
Concentrations of HIV protease inhibitors increase with ageMichael Carter | 11 years ago Plasma concentrations of protease inhibitors increase with age, investigators from the United Kingd......MORE |
Review shows HIV self-testing to be acceptable, accurate and feasible, but finds little data on linkage to care for those testing HIV-positiveMichael Carter | 11 years ago Self-testing for HIV is highly acceptable to patients in a variety of settings, investigators repor......MORE |
Review shows HIV self-testing to be acceptable, accurate and feasible, but finds little data on linkage to care for those testing HIV positiveMichael Carter | 11 years ago Self-testing for HIV is highly acceptable to people in a variety of settings, investigators report ......MORE |
KS-associated IRIS common among people starting HIV therapy in AfricaMichael Carter | 11 years ago Over 13% of people with HIV-related Kaposi’s sarcoma experience a worsening of disease after star......MORE |
Tenofovir and 3TC prevent new hepatitis B infections in gay men living with HIVMichael Carter | 11 years ago The inclusion of 3TC or tenofovir in antiretroviral treatment regimens reduces the risk of infectio......MORE |
Drinking coffee halves the risk of liver cancerMichael Carter | 11 years ago Coffee consumption reduces the risk of liver cancer by approximately 50%, the results of a meta-ana......MORE |
Very high incidence of high-grade pre-cancerous anal lesions among young HIV-positive Thai gay menMichael Carter | 11 years ago Approximately a third of HIV-positive gay men in Thailand developed high-grade pre-cancerous anal l......MORE |
Long-term suppression of viral load and sustained CD4 cell increase reduce risk of cervical HPV infection for HIV-positive womenMichael Carter | 11 years ago HIV therapy that achieves long-term suppression of viral load and sustained immune reconstitution r......MORE |
Recruitment through social networks is an efficient way to increase demand for HIV testing among high-risk groupsRoger Pebody | 11 years ago A pilot project which used a peer recruitment strategy, financial incentives and the involvement of......MORE |
Almost three-quarters of people starting HIV therapy in Tanzania have dyslipidemia after three years of treatmentMichael Carter | 11 years ago Approximately 75% of HIV-positive patients in Tanzania had lipid abnormalities three years after st......MORE |
Point-of-care viral load testing potentially cost-effective in southern AfricaCarole Leach-Lemens | 11 years ago Routine point-of-care viral load (POC-VL) tests with detection limits of 1000 copies/ml or below wi......MORE |
Meta-analysis shows the massive global burden of HIV among transgender womenMichael Carter | 11 years ago Almost a fifth of transgender women worldwide are infected with HIV, results of a meta-analysis pub......MORE |
Sexual transmission of hepatitis C very rare in monogamous heterosexual couplesMichael Carter | 11 years ago Sexual transmission of hepatitis C virus (HCV) among monogamous heterosexual couples is extremely r......MORE |
Quality of health services is key in encouraging or discouraging people from HIV testing in AfricaRoger Pebody | 11 years ago The uptake of HIV testing in sub-Saharan Africa is influenced by the quality and manner in which h......MORE |
Steroids reduce mortality risk for people taking TB treatmentMichael Carter | 11 years ago Corticosteroid treatment is associated with a reduced risk of mortality for people taking tuberculo......MORE |
People doing well on HIV therapy "should be eligible" for life insurance coverMichael Carter | 11 years ago The long-term effectiveness of antiretroviral therapy means that many HIV-positive people should be......MORE |
Self-testing and home treatment initiation triples uptake of HIV treatment in MalawiKeith Alcorn | 11 years ago Offering people the opportunity to self-test at home and then start antiretroviral therapy after co......MORE |
Routine tests prompted by electronic patient records increase rates of STI diagnoses among HIV-positive people in LondonMichael Carter | 11 years ago The implementation of systematic, frequent and routine screening for sexually transmitted infection......MORE |
Sofosbuvir plus ribavirin works well for hard-to-treat inner-city hepatitis C patientsLiz Highleyman | 11 years ago A simple 24-week oral regimen consisting of sofosbuvir plus full-dose ribavirin cured nearly 70% of......MORE |
AbbVie interferon-free combinations cure most newly treated hepatitis C patientsLiz Highleyman | 11 years ago All-oral regimens consisting of the HCV protease inhibitor ABT-450, a non-nucleoside polymerase inh......MORE |
Lukewarm reaction to government’s sexual health framework for EnglandRoger Pebody | 11 years ago Just two weeks before local authorities take over the commissioning of sexual health services – a......MORE |
HIV increases the risk of heart attack, even in people with a suppressed viral loadMichael Carter | 11 years ago Infection with HIV is associated with an increased risk of heart attack, investigators from the Uni......MORE |
Even moderate alcohol consumption increases risk of death for people with chronic hepatitis CMichael Carter | 11 years ago Moderate alcohol consumption - as little as one or two drinks per day - is associated with an inc......MORE |
French researchers report 14 patients in 'remission' after controlling HIV for over 4 years off treatmentGus Cairns | 11 years ago Two weeks ago, the announcement that a baby had been ‘functionally cured’ of HIV disease with t......MORE |
Are we underestimating the proportion of virally-suppressed patients in the US?Gus Cairns | 11 years ago Several presentations at the recent 20th Conference on Retroviruses and Opportunistic Infections in......MORE |
Lopinavir/ritonavir equivalent to nevirapine in Ugandan childrenCarole Leach-Lemens | 11 years ago A ritonavir-boosted lopinavir (LPV/r)-based regimen achieved a comparable rate of virologic suppres......MORE |
Gene therapy studies show potential for HIV control without drugsGus Cairns | 11 years ago Gene therapy approaches that involve the genetic modification of human haematopoietic stem cells ha......MORE |
Adding telaprevir improves acute hepatitis C treatment for HIV-positive menLiz Highleyman | 11 years ago Adding telaprevir (Incivo or Incivek) to pegylated interferon and ribavirin shortens the duration o......MORE |
Simeprevir & sofosbuvir demonstrates good early cure rate with or without ribavirinLiz Highleyman | 11 years ago An all-oral combination of simeprevir plus sofosbuvir, with or without ribavirin, led to an early c......MORE |
Malawi achieves seven-fold increase in ART for pregnant and breastfeeding womenCarole Leach-Lemens | 11 years ago Eighteen months after implementation of 'Option B+' in Malawi – ART for life for all HIV-infected......MORE |
Routine viral load monitoring almost halves risk of virologic failure in 18-month Kenyan studyLesley Odendal | 11 years ago Six-monthly viral load testing of patients taking antiretroviral therapy (ART) at primary health cl......MORE |
Faldaprevir ups interferon response in HIV/HCV co-infectionLiz Highleyman | 11 years ago Adding the hepatitis C virus (HCV) protease inhibitor faldaprevir (formerly BI 201335) to pegylated......MORE |
Simeprevir pushes HCV cure rate above 75% for HIV/HCV co-infectionLiz Highleyman | 11 years ago Adding the new hepatitis C virus (HCV) protease inhibitor simeprevir (formerly TMC435) to pegylated......MORE |
Contraceptive injections and HIV infection risk – a public health conundrumRoger Pebody | 11 years ago The concerns about a possible increase in risk of HIV acquisition with some hormonal contraceptive ......MORE |
New integrase inhibitor dolutegravir helps treatment-experienced people on failing therapyLiz Highleyman | 11 years ago The next-generation integrase inhibitor dolutegravir proved more beneficial than raltegravir (Isent......MORE |
Second-line NRTI-sparing regimen proves equally effective for resource-limited settingsKeith Alcorn | 11 years ago A second-line antiretroviral regimen of lopinavir/ritonavir (Kaletra/Aluvia) and raltegravir (Isent......MORE |
Can people with resistant HIV omit NRTIs when switching from a failing regimen?Liz Highleyman | 11 years ago Omitting nucleoside reverse transcriptase inhibitors (NRTIs) when switching from a non-suppressive ......MORE |
New pro-drug tenofovir alafenamide appears equally effective but better toleratedLiz Highleyman | 11 years ago Tenofovir alafenamide fumarate or TAF (formerly GS-7340), a new pro-drug of the widely used NRTI te......MORE |
Slow progress in expansion of voluntary circumcision coverageGus Cairns | 11 years ago Progress towards greater coverage of voluntary male circumcision (MC) in Africa remains slow, and i......MORE |
Dosing of key TB drug rifampicin could go higherKeith Alcorn | 11 years ago Rifampicin, a key drug in tuberculosis (TB) treatment, can be tolerated at much higher doses than u......MORE |
Once-weekly continuation phase TB treatment equals standard of careKeith Alcorn | 11 years ago A new two-drug combination of rifapentine and moxafloxacin can allow tuberculosis (TB) treatment to......MORE |
UK healthcare workers need better information and guidance on HIV criminalisationRoger Pebody | 11 years ago Support services for people living with HIV would benefit from better information and support aroun......MORE |
Dually active antiretroviral therapy protects against hepatitis B infectionLiz Highleyman | 11 years ago Use of antiretroviral therapy that includes drugs active against both hepatitis B virus (HBV) and H......MORE |
Dually active antiretroviral therapy protects against hepatitis B infectionKeith Alcorn | 11 years ago Use of antiretroviral therapy that includes drugs active against both hepatitis B virus (HBV) and H......MORE |
Continuing cotrimoxazole in children on ART reduces the risk of hospitalisationCarole Leach-Lemens | 11 years ago Children on ART for more than two years who continued taking daily cotrimoxazole had significantly ......MORE |
Black gay men run higher risk of HIV infection despite fewer partnersGus Cairns | 11 years ago An analysis of four studies of sexual risk and HIV infection in US gay men, presented at the 20th C......MORE |
New NNRTI MK-1439 shows promise in early clinical trialLiz Highleyman | 11 years ago A next-generation non-nucleoside reverse transcriptase inhibitor (NNRTI), MK-1439, demonstrated rob......MORE |
Dual CCR5/CCR2 inhibitor cenicriviroc has anti-inflammatory as well as anti-HIV effectLiz Highleyman | 11 years ago Cenicriviroc, which blocks both CCR5 and CCR2 receptors on immune cells, is effective against HIV, ......MORE |
Small risk of neurological birth defects due to efavirenz confirmed in French cohortKeith Alcorn | 11 years ago A large French study has found an elevated risk of some birth defects in children born to women exp......MORE |
HIV treatment for children is safe and highly effective without laboratory monitoring in large African trialKeith Alcorn | 11 years ago Children did just as well on antiretroviral therapy without routine laboratory monitoring of CD4 ce......MORE |
French studies report real-world data on use of telaprevir and boceprevir in people with HIV and hepatitis C co-infectionLiz Highleyman | 11 years ago Adding boceprevir or telaprevir to interferon-based therapy showed promising indications of efficac......MORE |
Very early antiretroviral treatment limits the size of HIV reservoirKeith Alcorn | 11 years ago Very early antiretroviral treatment may limit the size of the HIV reservoir in adults and children,......MORE |
Sofosbuvir/ledipasvir/ribavirin cures 100% of genotype 1 hepatitis C patientsLiz Highleyman | 11 years ago An interferon-free regimen containing sofosbuvir (formerly GS-7997), ledipasvir (formerly GS-5885)......MORE |
Consistent condom use in anal sex stops 70% of HIV infections, study finds, but intermittent use has no effectGus Cairns | 11 years ago An analysis by Dawn Smith of the US Centers for Disease Control (CDC) reported at the 20th Confere......MORE |
Monthly injectable drug offers 100% protection against HIV in monkeys – could be dosed every three monthsGus Cairns | 11 years ago An injectable, long-lasting integrase inhibitor drug, when given to rhesus macaques exposed to a mo......MORE |
VOICE trial's disappointing result poses big questions for PrEPGus Cairns | 11 years ago The failure of one of the largest trials yet conducted of HIV drug-based prevention methods poses q......MORE |
Case report of a 'functional' HIV cure in a childKeith Alcorn | 11 years ago Researchers in the United States today said that they have identified a case of a 'functional' HIV......MORE |
US gay youth PrEP study meets recruitment and adherence problemsGus Cairns | 11 years ago A small six-month pilot study of the feasibility and acceptability of pre-exposure prophylaxis (PrE......MORE |
US gay youth PrEP study meets retention and adherence problemsGus Cairns | 11 years ago A small six-month pilot study of the feasibility and acceptability of pre-exposure prophylaxis (PrE......MORE |
In resource-rich countries, migrants have a higher risk of progressing to AIDS in the first year of HIV therapyMichael Carter | 11 years ago Rates of AIDS-defining illnesses in the first year of antiretroviral therapy are significantly high......MORE |
Study shows value of hepatitis C therapy for HIV co-infected patients with compensated cirrhosisMichael Carter | 11 years ago Spanish research published in the online edition of Clinical Infectious Diseases shows the benefits......MORE |
Meta-analysis shows superiority of integrase inhibitors in first-line HIV therapy and benefits for people changing treatment due to resistanceMichael Carter | 11 years ago Antiretroviral combinations based on an integrase inhibitor are superior to other first-line HIV tr......MORE |
Variations in genital shedding of HIV during menstrual cycle large enough to impact on risk of sexual transmissionMichael Carter | 11 years ago Genital shedding of HIV varies considerably during the menstrual cycle, investigators report in the......MORE |
Low nadir CD4 cell count associated with increased cataract risk in South Africans taking HIV therapyMichael Carter | 11 years ago A low nadir (lowest ever) CD4 cell count is associated with increased lens density – a marker for......MORE |
Earlier treatment in South African cohort did not increase loss to follow-upCarole Leach-Lemens | 11 years ago Implementation of South Africa’s 2011 expansion of treatment guidelines – starting antiretrovir......MORE |
Classic characteristics of old age associated with poor physical function in middle-aged people living with HIVMichael Carter | 11 years ago Impaired physical function in middle-aged people living with HIV is associated with low reduced mus......MORE |
Many people with HIV not disclosing at GUM clinics: estimates of undiagnosed infections may be too highMichael Carter | 11 years ago Many people with HIV are not disclosing their status when using sexual health clinics, according to......MORE |
Triple trouble: infection with hepatitis B increases risk of death for people with HIV and hepatitis C co-infectionMichael Carter | 11 years ago Infection with hepatitis B virus (HBV) is associated with a poorer prognosis for people living with......MORE |
Combining tenofovir with FTC or 3TC boosts chances of HBV suppression for people co-infected with HIVMichael Carter | 11 years ago A study involving people co-infected with HIV and hepatitis B virus (HBV) shows that antiretroviral......MORE |
Frailty increases the risk of fragility fractures in men living with HIV: data collected in routine HIV care can help predict riskMichael Carter | 11 years ago Important physiologic markers of frailty are associated with fragility fractures in men living with......MORE |
Couples study in Uganda finds no HIV infections from partners on antiretroviral therapyGus Cairns | 11 years ago A longitudinal cohort study of heterosexual couples in Uganda has found more evidence of the effica......MORE |
Condoms used in one-in-four heterosexual encounters in the USGus Cairns | 11 years ago A quarter of heterosexual adults in the United States used a condom the last time they had vaginal ......MORE |
Tenofovir, atazanavir/ritonavir and Kaletra associated with kidney problems in patients taking HIV therapyMichael Carter | 11 years ago Data from a large study into the safety of anti-HIV drugs suggests that the antiretrovirals tenofov......MORE |
Media campaign on acute HIV infection symptoms has limited impactRoger Pebody | 11 years ago A advertising campaign and website that aimed to raise awareness among gay men in Seattle, Washingt......MORE |
More evidence of sexual transmission of hepatitis C among HIV-positive gay men in the USMichael Carter | 11 years ago Investigators in the US have found a high incidence of hepatitis C virus (HCV) infection among HIV-......MORE |
Circumcision makes no difference to HIV infection in UK gay menGus Cairns | 11 years ago An analysis of an online and gay-venue survey of white, British-born, gay and bisexual men in the U......MORE |
Was higher viral load responsible for the African HIV epidemic?Gus Cairns | 11 years ago Researchers from Cornell University in New York have found that the average HIV viral load of peopl......MORE |
Crystal meth and London gay men – examining the evidenceRoger Pebody | 11 years ago Last month the respected medical journal The Lancet published a news feature, describing an increas......MORE |
Test and treat must go beyond couples to control HIV in AfricaMichael Carter | 11 years ago A focus on stable couples when attempting to reduce HIV transmission through offering antiretrovira......MORE |
Neonatal male circumcision feasible in resource-limited settings; Mogen clamp may have advantagesMichael Carter | 11 years ago Neonatal male circumcision can be safely performed in resource-limited settings, according to the r......MORE |
Pregnancy does not increase risk of nevirapine side-effectsMichael Carter | 11 years ago Pregnancy does not increase the risk of nevirapine (Viramune) associated side-effects, according to......MORE |
AIDS-defining illnesses, especially TB, more frequent at high CD4 counts in Africa and AsiaCarole Leach-Lemens | 11 years ago Rates of death and illness remained 'substantial' even at higher CD4 cell counts among people recei......MORE |
'Intensive' antiretroviral regimen achieves rapid suppression of HIV in semenMichael Carter | 11 years ago Adding maraviroc and raltegravir to standard HIV treatment regimens achieves rapid suppression of v......MORE |
Results of TB vaccine trial give cause for optimism, say researchersMichael Carter | 11 years ago Results of a trial have been praised for “providing hard evidence about protection against tuberc......MORE |
HIV incidence in gay men unchanged in England and Wales, despite more testingGus Cairns | 11 years ago A paper in The Lancet by scientists from the UK’s Medical Research Council and the Health Protect......MORE |
Tenofovir impairs enzyme that stops cells ageingGus Cairns | 11 years ago A team of Australian researchers has found that tenofovir and, to a lesser extent, other drugs from......MORE |
Spanish research shows that liver stiffness can predict outcomes in people co-infected with HIV and hepatitis CMichael Carter | 11 years ago Liver stiffness is a strong predictor of hepatic complications and all-cause mortality in people co......MORE |
Hospital exposure the source of XDR-TB infections, underlining the need for adequate infection controlMichael Carter | 11 years ago Numerous hospital transmissions – rather than a single source – fuelled the outbreak of extensi......MORE |
Screening can reduce number of patients in need of a doctor's time in busy South African clinicCarole Leach-Lemens | 11 years ago Screening patients to identify those who are stable on treatment in a high-volume, large urban publ......MORE |
Systematic review confirms that efavirenz is a safer option than nevirapine for adults and children starting HIV therapyMichael Carter | 11 years ago Efavirenz is a safer option than nevirapine for adults and children starting antiretroviral therapy......MORE |
Support needed to prevent missed clinic visits becoming long-term disengagement from careRoger Pebody | 11 years ago Missed clinic visits may be unintentional or intentional, with complex reasons that change over tim......MORE |
Co-infection with hepatitis B or C is a risk factor for reduced bone mineral density among women with HIVMichael Carter | 11 years ago Co-infection with hepatitis B or C is associated with reduced bone mineral density (BMD) in women l......MORE |
Mortality rates continue to fall in the Swiss HIV cohortMichael Carter | 11 years ago Mortality in people with HIV is continuing to fall, Swiss investigators report in HIV Medicine. The......MORE |
UK experts: successful treatment is "as effective as consistent condom use" in reducing HIV transmissionRoger Pebody | 11 years ago The British HIV Association (BHIVA) and the Department of Health’s Expert Advisory Group on AIDS ......MORE |
Nigeria: Drug resistance data show merits of using tenofovir in first-line ART regimensCarole Leach-Lemens | 11 years ago People living with HIV in Nigeria, at high risk for virological failure, on a tenofovir (TDF)-based......MORE |
Prevalence of drug-resistant HIV has fallen dramatically among antiretroviral-experienced patients in Western EuropeMichael Carter | 11 years ago There has been a significant fall in the proportion of HIV-positive people in Western Europe with e......MORE |
Australian researchers project that many HIV-positive people will run out of treatment optionsMichael Carter | 11 years ago Running out of antiretroviral treatment options may severely curtail the life expectancy of people ......MORE |
Large study shows the hepatic safety of HIV therapyMichael Carter | 11 years ago Results from a large study published in the online edition of Clinical Infectious Diseases provide ......MORE |
Prevalence of drug-resistant HIV has fallen dramatically among antiretroviral-experienced patients in Western EuropeMichael Carter | 11 years ago There has been a significant fall in the proportion of HIV-positive people in Western Europe with......MORE |
Management of hypertension reduces the risk of cardiovascular disease for HIV-positive people with high blood pressureMichael Carter | 11 years ago New Swiss research has shown the benefits of treating hypertension in HIV-positive people. The inv......MORE |
Six-monthly CD4 cell monitoring 'unnecessary' for people doing well on HIV therapyMichael Carter | 11 years ago CD4 cell count monitoring more than once a year is unnecessary for people doing well on HIV therapy......MORE |
CMV infection may contribute to the size of the latent HIV reservoirMichael Carter | 11 years ago The presence of cytomegalovirus (CMV) in blood and semen is associated with higher levels of HIV DN......MORE |
Steep fall in incidence of TB among HIV-positive heterosexuals in the UKMichael Carter | 11 years ago Incidence of tuberculosis (TB) among HIV-positive heterosexual people in England and Wales declined......MORE |
Treatment with raltegravir increases the risk of mild muscular side-effectsMichael Carter | 11 years ago Treatment with the HIV integrase inhibitor raltegravir (Isentress) is associated with an increased ......MORE |
Awareness rises following PEP communicationsRoger Pebody | 11 years ago Gay men’s awareness of HIV post-exposure prophylaxis (PEP) significantly improved in Western Aust......MORE |
Low uptake of behavioural interventions by gay men at English sexual health clinicsRoger Pebody | 11 years ago Only a quarter of gay men who had had unprotected sex were offered and accepted a structured interv......MORE |
Young people know less about HIV and are less trustful of condoms, French survey findsGus Cairns | 11 years ago The first survey for six years of attitudes to HIV and sexual risk behaviour among the general publ......MORE |
Hepatitis B treatment and care in the UK need to evolve to keep pace with the global epidemicMichael Carter | 11 years ago “Persistent HBV [hepatitis B virus] infection has changed its face in the UK,” research publish......MORE |
Any reduction in viral load has immunologic benefits for people with HIV who have triple-class treatment failureMichael Carter | 11 years ago HIV therapy that achieves even modest reductions in viral load can have profound immunological bene......MORE |
Neurocognitive impairment results in poorer adherence to HIV therapyMichael Carter | 11 years ago Neurocognitive impairment and problems with memory are associated with poorer adherence to antiretr......MORE |
Small UK study suggests that depression does not have an impact on hepatitis C treatment outcomes in people co-infected with HIVMichael Carter | 11 years ago Depression does not influence hepatitis C treatment outcomes in people co-infected with HIV, accord......MORE |
US research shows that HPV vaccination could prevent pre-cancerous anal cell changes in HIV-positive gay menMichael Carter | 11 years ago Vaccination against cancer-associated strains of human papillomavirus (HPV) could be highly effecti......MORE |
Support improves hepatitis C treatment completion and response rates among drug usersMichael Carter | 11 years ago Hepatitis C treatment completion and response rates among injecting drug users are similar to those......MORE |
Smoking has a bigger impact on the prognosis of HIV-positive patients than HIV-related factorsMichael Carter | 11 years ago Much of the increased mortality seen in patients with HIV can be attributed to smoking, Danish inve......MORE |
Aggressive therapy for MDR-TB reduces risk of disease recurrenceMichael Carter | 11 years ago Aggressive treatment of multidrug-resistant tuberculosis (MDR-TB) significantly reduces the risk of......MORE |
Poor CD4 response to HIV treatment increases risk of death from non-AIDS-related illnesses, even for those with higher baseline countsMichael Carter | 11 years ago A poor increase in CD4 cell count after starting antiretroviral therapy is associated with an incre......MORE |
Child death rates still high despite HIV treatmentCarole Leach-Lemens | 11 years ago Barely half of all children having started antiretroviral treatment (ART) at under one year of age ......MORE |
Combined oral contraception has less effect on nevirapine than efavirenz levelsMichael Carter | 11 years ago HIV therapy based on efavirenz may less suitable for women taking combined oral contraception due t......MORE |
Vitamin D deficiency increases risk of TB among people starting HIV therapyMichael Carter | 11 years ago Vitamin D deficiency is associated with an increased risk of pulmonary tuberculosis (TB), oral thru......MORE |
Liver cancer has a more aggressive disease course in HIV-positive people co-infected with viral hepatitisMichael Carter | 11 years ago Co-infection with HIV and viral hepatitis is associated with a more aggressive disease course for l......MORE |
Treatment with a protease inhibitor during the first trimester of pregnancy increases the risk of pre-term birthMichael Carter | 11 years ago Further evidence has emerged from research in the United States that antiretroviral therapy based o......MORE |
Traditional risk factors strongest predictors of sub-clinical cardiovascular disease in people about to start HIV therapyMichael Carter | 11 years ago Sub-clinical cardiovascular disease in people with HIV is more strongly associated with traditional......MORE |
Study of South African sex worker characteristics could assist in informing policy decisionsLesley Odendal | 11 years ago Male and transgender sex workers in South Africa are at particularly high risk of HIV infection and......MORE |
Adding pegylated interferon to entecavir improves hepatitis B treatment responseLiz Highleyman | 11 years ago Intensifying entecavir (Baraclude) treatment for hepatitis B by adding pegylated interferon lowers ......MORE |
Adherence to hepatitis C treatment: unravelling the complexitiesRob Camp | 11 years ago Successful adherence to hepatitis C treatment may require physicians and care teams to address a wi......MORE |
Is a simple sofosbuvir plus ribavirin regimen suitable for difficult-to-treat hepatitis C patients?Liz Highleyman | 11 years ago An all-oral dual regimen of sofosbuvir (GS-7977) plus full-dose ribavirin was well-tolerated and p......MORE |
Low-dose stavudine study debated between South African researchers and activistsLesley Odendal | 11 years ago A proposed trial of low-dose stavudine (also known as d4T) sparked a heated debate between South A......MORE |
HIV and hepatitis C co-infection increases the risk of cognitive impairmentMichael Carter | 11 years ago Co-infection with HIV and hepatitis C is associated with an increased risk of cognitive impairment,......MORE |
Exclusive breastfeeding hampered by infant illnesses, follow up of mothers with HIV showsKeith Alcorn | 11 years ago Only one third of women counselled to exclusively breast feed for six months in the Kesho Bora stud......MORE |
Exclusive breastfeeding hampered by infant illnesses, follow up of mothers with HIV showsCarole Leach-Lemens | 11 years ago Only one third of women counselled to exclusively breast feed for six months in the Kesho Bora stud......MORE |
Diet quality predicts HIV progression and death in resource-poor settingsCarole Leach-Lemens | 11 years ago The more diverse and nutrient-rich the diet before starting antiretroviral treatment (ART), the les......MORE |
Hepatitis C patients with cirrhosis respond well to boceprevir or telaprevir with careful monitoringLiz Highleyman | 11 years ago Real-world experience in the French early-access CUPIC cohort shows that hepatitis C patients with ......MORE |
Brivanib fails to match sorafenib for liver cancer, but tivantinib looks promisingLiz Highleyman | 11 years ago The investigational cancer drug brivanib did not significantly increase survival for people with he......MORE |
Couples HIV testing and counselling prompts rapid switch to consistent condom use in South African studyCarole Leach-Lemens | 11 years ago HIV testing and counselling of couples quickly led to consistent condom use among serodiscordant co......MORE |
Swiss research identifies factors associated with use of non-recommended HIV therapyMichael Carter | 11 years ago New Swiss research shows the importance of observing antiretroviral treatment guidelines, even in p......MORE |
'Real-world' evidence shows that antiretroviral therapy reduces risk of HIV transmission in heterosexual couplesMichael Carter | 11 years ago A study conducted in China has provided 'real-world' evidence of the impact of antiretroviral thera......MORE |
"Real world" evidence shows that antiretroviral therapy reduces risk of HIV transmission in heterosexual couplesMichael Carter | 11 years ago A study conducted in China has provided “real world” evidence of the impact of antiretroviral t......MORE |
FDA Advisory Committee recommends accelerated approval of bedaquiline for drug-resistant TBLesley Odendal | 11 years ago Bedaquiline, the first agent in a new class of TB drug, has been recommended for accelerated approv......MORE |
Out-of-clinic adherence club for delivery of ARVs shows better retention than standard of careLesley Odendal | 11 years ago An out-of-clinic model of HIV treatment delivery in South Africa has shown superior results to the ......MORE |
Telaprevir and VX-222 pair well in interferon-free regimen, VX-135 on the horizonKeith Alcorn | 11 years ago An all-oral regimen of telaprevir, VX-222 and ribavirin for 12 weeks was generally well-tolerated a......MORE |
Telaprevir and VX-222 pair well in interferon-free regimen, VX-135 on the horizonLiz Highleyman | 11 years ago An all-oral regimen of telaprevir, VX-222 and ribavirin for 12 weeks was generally well-tolerated a......MORE |
HPA urges further action on HIV testing to reduce numbers undiagnosed and diagnosed lateRoger Pebody | 11 years ago The Health Protection Agency (HPA) issued its annual epidemiological report yesterday, and drew par......MORE |
UK clinicians define minimum standards of HIV care – for a changing NHSRoger Pebody | 11 years ago The British HIV Association (BHIVA) yesterday published a document which outlines the standard of c......MORE |
Very high rates of HIV infection among gay/bisexual male youths in the United StatesMichael Carter | 11 years ago Over a quarter of new HIV infections in the US involve youths aged between 13 and 24, investigators......MORE |
Nucleoside analogues reduce hepatitis B liver cancer riskLiz Highleyman | 11 years ago Treatment of chronic hepatitis B with nucleoside analogues including lamivudine (Epivir) and enteca......MORE |
Starting HIV therapy with a viral load above 100,000 is associated with a lower chance of achieving an undetectable viral loadMichael Carter | 11 years ago Starting HIV treatment with a viral load above 100,000 copies/ml is associated with a reduced chanc......MORE |
Sharing drug preparation equipment a potential source of hepatitis C transmissionMichael Carter | 11 years ago Drug users who share injecting equipment such as water, filters and water containers are potentiall......MORE |
Low levels of vitamin D associated with poorer long-term CD4 cell gains in women who start HIV treatment lateMichael Carter | 11 years ago Vitamin D insufficiency is associated with poorer CD4 cell recovery among women who start HIV treat......MORE |
Dutch find low bone mineral density in gay men, regardless of HIV infection statusMichael Carter | 11 years ago The prevalence of low bone mineral density (BMD) is similar in HIV-positive and HIV-negative gay me......MORE |
Abacavir: new studies challenge the evidence of reduced potency when viral load is highGus Cairns | 11 years ago An analysis of two studies of the new HIV integrase inhibitor dolutegravir presented at the Elevent......MORE |
Telaprevir twice-daily works as well as every eight hours, safe for hepatitis C patients with cirrhosisKeith Alcorn | 11 years ago The HCV protease inhibitor telaprevir (Incivo or Incivek) taken twice daily with pegylated interfer......MORE |
Telaprevir twice-daily works as well as every eight hours, safe for hepatitis C patients with cirrhosisLiz Highleyman | 11 years ago The hepatitis C protease inhibitor telaprevir (Incivo or Incivek) taken twice daily with pegylated ......MORE |
Which patients should be prioritised for new hepatitis C treatments?Rob Camp | 11 years ago Younger patients with advanced liver disease caused by hepatitis C should be prioritised for treatm......MORE |
Low viral load in hepatitis C treatment: Is a third drug necessary?Rob Camp | 11 years ago When resources for hepatitis C treatment with new directly acting antivirals are limited, findings ......MORE |
Even in well-treated populations, loss to follow-up limits community viral suppressionGus Cairns | 11 years ago Several papers presented at the Eleventh International Congress on Drug Therapy in HIV Infection la......MORE |
Even in well-treated populations, loss to follow up limits community viral suppressionGus Cairns | 11 years ago Several papers presented at the Eleventh International Congress on Drug Therapy in HIV Infection la......MORE |
Tenofovir safe and effective for long-term hepatitis B treatment with little bone lossLiz Highleyman | 11 years ago Tenofovir (Viread) continues to be safe and effective for treating chronic hepatitis B through eigh......MORE |
Unprotected sex reported by the majority of sexually active adolescents infected with HIV since birthMichael Carter | 11 years ago Close to two-thirds of sexually active adolescents infected with HIV at birth have had unprotected ......MORE |
Sofosbuvir and daclatasvir dual regimen cures most people with HCV genotypes 1, 2, or 3Liz Highleyman | 11 years ago A 12-week, once-daily regimen of the hepatitis C (HCV) polymerase inhibitor sofosbuvir and the NS5A......MORE |
New fixed-dose combination pills measure up to AtriplaGus Cairns | 11 years ago Several studies, or updates of studies, comparing newer against older drug regimens were presented ......MORE |
New fixed-dose combination pills measure up to Atripla - corrected version*Gus Cairns | 11 years ago Several studies, or updates of studies, comparing newer against older drug regimens were presented ......MORE |
Interferon-free hepatitis C treatment with faldaprevir proves safe and effective in people with cirrhosisKeith Alcorn | 11 years ago The first major data on interferon-free hepatitis C treatment in people with cirrhosis show that tr......MORE |
Life expectancy in older people with HIV could exceed the average – as long as ART keeps workingGus Cairns | 11 years ago The latest forecasts of life expectancy in people with HIV in the UK, based on mortality data from ......MORE |
Simeprevir is safe and effective with interferon/ribavirin for hepatitis C patients with cirrhosisLiz Highleyman | 11 years ago The hepatitis C protease inhibitor simeprevir (formerly TMC435) was generally safe and well tolerat......MORE |
Smoking the biggest single risk factor for acute heart disease in people with HIVMichael Carter | 11 years ago Smoking is the single biggest risk factor for acute coronary syndrome in HIV-positive adults, Spani......MORE |
Lack of understanding of treatment benefits may discourage women with HIV from having children – and could increase the risk of vertical transmissionGus Cairns | 11 years ago Two papers presented at the Eleventh International Congress on Drug Therapy in HIV Infection this w......MORE |
Interferon-free hepatitis C treatment safe, proves effective in up to 63% of patients with cirrhosisKeith Alcorn | 11 years ago The first major data on interferon-free hepatitis C treatment in people with cirrhosis shows that t......MORE |
Manchester study finds link between increased premature birth rate and HIVGus Cairns | 11 years ago A review of clinical records from North Manchester University Hospital has found more evidence of a......MORE |
Sofosbuvir demonstrates high response rate in interferon-free combination with ribavirin and GS-5555Liz Highleyman | 11 years ago The hepatitis C polymerase inhibitor sofosbuvir produced high rates of sustained virological respon......MORE |
Half of HIV-positive gay men disagree that HIV treatment makes you less infectiousGus Cairns | 11 years ago A survey of over 2000 gay men attending clinics in the UK has found that 48% disagree that HIV trea......MORE |
Sofosbuvir demonstrates high response rate in interferon-free combination with ribavirin and GS-5885Liz Highleyman | 11 years ago The hepatitis C polymerase inhibitor sofosbuvir produced high rates of sustained virological respon......MORE |
94% response rate to HCV treatment without ribavirin or interferon in harder-to-treatKeith Alcorn | 11 years ago Twelve weeks of treatment with a three-drug combination of new directly acting antivirals that cont......MORE |
Reducing ribavirin and adding EPO are both good anaemia management strategies for people taking boceprevirLiz Highleyman | 11 years ago Chronic hepatitis C patients treated with boceprevir (Victrelis) plus pegylated interferon and riba......MORE |
Abbott interferon-free combination 'promising' in harder-to-treat patients with hepatitis CKeith Alcorn | 11 years ago Over 79% of previously untreated and null responder patients with genotype 1a hepatitis infection a......MORE |
High rate of response to BMS HCV drugs in harder-to-treat patients – but interferon-free prospects differ by sub-genotypeKeith Alcorn | 11 years ago Although an interferon-free combination of antiviral drugs developed by Bristol-Myers Squibb to tre......MORE |
Final study results show telaprevir is safe and effective for HIV/HCV co-infected peopleLiz Highleyman | 11 years ago HIV/HCV co-infected people treated with telaprevir (Incivo) triple therapy are significantly more l......MORE |
New hepatitis C drugs danoprevir and mericitabine are safe and effective for prior non-responders and people with cirrhosisLiz Highleyman | 11 years ago The experimental hepatitis C drugs danoprevir and mericitabine, with or without pegylated interfero......MORE |
New cohort shows the impact of hepatitis B and hepatitis C on the 'baby boom' generationMichael Carter | 11 years ago A new US study provides more evidence of the disproportionate impact of viral hepatitis infections ......MORE |
Some sexual lubricants damage cells – but may not increase HIV riskGus Cairns | 11 years ago An evaluation of 13 sexual lubricants has found that, while many are toxic to the cells that line t......MORE |
Only half of people on HIV treatment fit 'Swiss Statement' criteria for non-infectiousness in US studyGus Cairns | 11 years ago A study of a sample of predominantly African-American people with HIV in the US has found that, in ......MORE |
Sexual preference is a better guide to HIV risk in gay men than reported behaviour, Chinese study suggestsGus Cairns | 11 years ago A study of men who have sex with men (MSM) in the city of Chongqing in China has found that HIV pre......MORE |
Young gay men with HIV in the UK worry about disclosure, transmission and prosecution – older ones about confidence and sexGus Cairns | 11 years ago A large majority of gay men in the UK with HIV describe having one or more problems with sex, an an......MORE |
Very high HIV incidence among men who have sex with men in KenyaMichael Carter | 11 years ago HIV incidence among men who have sex with men (MSM) in Kenya is as high as 35%, investigators repo......MORE |
Death rates elevated at all CD4 counts below 500 in sub-Saharan AfricaKeith Alcorn | 11 years ago A comparison of death rates between the HIV-positive and HIV-negative partners in serodiscordant co......MORE |
Starting HIV treatment reduces risky sexual behaviour among injecting drug usersMichael Carter | 11 years ago Starting antiretroviral therapy is associated with reductions in sexual risk-taking and injecting a......MORE |
Denmark: Late HIV diagnosis not a major factor in continued spread of HIVMichael Carter | 11 years ago Individuals whose HIV infection is diagnosed late are making only a minimal contribution to the HIV......MORE |
Spanish researchers urge more awareness campaigns on PEPGus Cairns | 11 years ago Only a third of gay men and one in six heterosexual people who came forward for a rapid HIV communi......MORE |
South African women who seek goods and services from sexual partners more likely to become HIV positive within two yearsRoger Pebody | 11 years ago Young South African women who engage in sex or have relationships partially motivated by economic ......MORE |
Traditional risk factors predict neurocognitive impairment in people with HIVMichael Carter | 11 years ago Neurocognitive impairment in people with HIV – loss of memory, poor concentration and declining m......MORE |
Adverse birth outcomes more frequent in women exposed to ART during pregnancy, largest-ever study confirmsCarole Leach-Lemens | 11 years ago Among HIV-infected women in Botswana starting combination antiretroviral therapy during pregnancy w......MORE |
Antiviral treatment reduces risk of liver cancer in people with hepatitis C-related cirrhosis and fibrosisMichael Carter | 11 years ago Antiviral treatment reduces the risk of hepatocellular carcinoma (HCC) in people with hepatitis C-r......MORE |
Dramatic increase in incidence of liver cancer in HIV-positive people with viral hepatitisMichael Carter | 11 years ago Incidence of liver cancer among people with HIV has increased dramatically over the past decade, Sp......MORE |
Over-the-counter blood test for HIV may be feasible, Spanish study findsGus Cairns | 11 years ago A study from Madrid has found that 92% of people taking an HIV test could obtain a valid result by ......MORE |
Scale up of HIV testing in Africa isn't leading to breaches in consent or confidentialityMichael Carter | 11 years ago Efforts to scale up HIV testing in sub-Saharan Africa have not resulted in breaches of patient righ......MORE |
Higher temperature and air pollution levels linked with PCP hospitalisations among people with HIVMichael Carter | 11 years ago Temperature and air pollution levels are associated with hospitalisations caused by Pneumocystis pn......MORE |
Health Protection Agency reports highest number of HIV diagnoses ever among gay and bisexual men in 2011Keith Alcorn | 11 years ago New figures from the Health Protection Agency released today show that although the total number of......MORE |
More evidence that rapid ‘combination’ test often fails to detect acute HIV infectionRoger Pebody | 11 years ago A rapid, point-of-care test, which aims to reduce the ‘window period’ through the detection of ......MORE |
Risk of recurrence of active TB is high for people with HIVMichael Carter | 11 years ago People living with HIV who have a history of active tuberculosis (TB) have a significant risk of th......MORE |
Viral load will be no defence against prosecution for HIV exposure or transmission in NorwayGus Cairns | 11 years ago HIV campaigners reacted with dismay today to the issuing of a report by a Norwegian Commission on H......MORE |
Huge differences in HIV mortality rates in US according to race, social and economic statusMichael Carter | 11 years ago New US research has revealed enormous differences in HIV mortality rates between patients according......MORE |
High-dose multivitamins have no benefit for people starting HIV treatment but cause serious liver disturbancesMichael Carter | 11 years ago Taking high-dose multivitamins has no health benefits for people starting antiretroviral therapy, b......MORE |
Cidofovir cream an effective and safe treatment for high-grade pre-cancerous HPV lesionsMichael Carter | 11 years ago Topical cidofovir cream had a 50% efficacy for the treatment of high-grade pre-cancerous anal and v......MORE |
European guidelines on management of mental health for people with hepatitis C publishedMichael Carter | 11 years ago European investigators have developed a consensus statement on hepatitis C and mental health. Publi......MORE |
Opiate substitution therapy halves HIV risk for people who inject drugsMichael Carter | 11 years ago Opiate substitution therapy reduces the risk of HIV infection by half for individuals who inject dr......MORE |
PrEP probably cost effective in middle-income countries, but too costly to slash HIV incidenceGus Cairns | 11 years ago What is probably the most detailed and realistic modelling study so far done of the impact and cost......MORE |
PrEP likely to be cost effective in middle-income countries, but its use will be too costly to make a big difference in HIV rateGus Cairns | 11 years ago What is probably the most detailed and realistic modelling study so far done of the impact and cost......MORE |
Frailty common among HIV-positive patients in South Africa, but early ART may be protectiveMichael Carter | 11 years ago Frailty is common among HIV-positive people in South Africa, investigators report in the online edi......MORE |
Vitamin D deficiency associated with a poorer response to HCV treatment in HIV/HCV-co-infected patientsMichael Carter | 11 years ago Vitamin D deficiency is associated with a poorer response to hepatitis C therapy in people who are ......MORE |
Obesity is a risk factor for co-occuring chronic health problems in patients with HIVMichael Carter | 11 years ago Obesity is associated with the clustering of multiple health problems in HIV-positive people, inves......MORE |
CNS symptoms common in people taking raltegravirMichael Carter | 11 years ago Approximately 10% of patients taking the antiretroviral drug raltegravir (Isentress) develop centra......MORE |
Starting HIV treatment reduces the risk of serious non-AIDS-related diseasesMichael Carter | 11 years ago Serious non-AIDS-defining illnesses are common in people recently diagnosed with HIV, Spanish inves......MORE |
Supreme Court of Canada rules that condoms alone do not prevent a 'realistic possibility' of HIV transmissionEdwin Bernard | 11 years ago The Supreme Court of Canada stated on Friday that individuals who know they are HIV-positive are li......MORE |
Factors associated with improved access to treatment and care for children with HIV in Africa identified in 5-country studyCarole Leach-Lemens | 11 years ago Nutritional support, early infant diagnosis (EID), linkages with associations of people living with......MORE |
UK government ends funding for HIV-specific phone helplinesRoger Pebody | 11 years ago The Department of Health has ended its support for the telephone helplines operated by Terrence Hi......MORE |
Dosing frequency and number of pills don't affect HIV treatment outcomesMichael Carter | 11 years ago Levels of adherence to modern HIV treatment are unaffected by dosing frequency or number of daily p......MORE |
Higher levels of adherence to hepatitis C therapy improve treatment outcomes in people with hepatitis C and HIVMichael Carter | 11 years ago Higher levels of adherence to pegylated interferon and ribavirin are associated with better hepatit......MORE |
Pain and worry common problems for people with HIV receiving palliative care in AfricaMichael Carter | 11 years ago People with HIV receiving palliative care have high levels of physical and psychological problems, ......MORE |
From today, HIV treatment is free for all who need it in EnglandRoger Pebody | 11 years ago The removal of charges for undocumented migrants and non-UK citizens accessing HIV treatment and ca......MORE |
Large study suggests that more African people are acquiring HIV in the UK than previously thoughtRoger Pebody | 11 years ago A new approach developed by scientists at the Health Protection Agency indicates that around 31% o......MORE |
Late start for ART in pregnancy increases HIV transmission risk during breastfeeding periodCarole Leach-Lemens | 11 years ago A high viral load at the time of starting treatment during pregnancy and a shorter time on antiretr......MORE |
Consistent and correct condom use reduces risk of bacterial STIs by 60%Michael Carter | 11 years ago Consistent and correct condom use provides a high level of protection against bacterial sexually tr......MORE |
Global evidence of lower adherence to ARVs after giving birthCarole Leach-Lemens | 11 years ago Antiretroviral therapy (ART) adherence levels among pregnant women with HIV, in both high- and low-......MORE |
Grindr smartphone app could be a good way to recruit gay men to HIV prevention studiesMichael Carter | 11 years ago Gay men can be effectively and efficiently recruited to HIV prevention studies using the Grindr sma......MORE |
Regular HIV testing becoming the norm among gay men in ScotlandMichael Carter | 11 years ago The number of gay men testing for HIV in Scotland increased significantly between 2000 and 2010, a ......MORE |
Primary HIV infection frequently missed by GUM and HIV clinicsMichael Carter | 11 years ago Primary HIV infection is frequently missed in people newly diagnosed with HIV, investigators from t......MORE |
Switching to tenofovir suppresses hepatitis B in HIV/HBV co-infected peopleKeith Alcorn | 11 years ago People with HIV and hepatitis B virus (HBV) co-infection, who substituted tenofovir (Viread) for zi......MORE |
Switching to tenofovir suppresses hepatitis B in HIV/HBV co-infected peopleLiz Highleyman | 11 years ago People with HIV and hepatitis B virus (HBV) co-infection, who substituted tenofovir (Viread) for zi......MORE |
False-negative confirmatory HIV tests in children are frequent after starting ARTCarole Leach-Lemens | 11 years ago False-negative rapid antibody tests, in the absence of virologic testing at the age of 18 months, i......MORE |
ART for life cost effective for prevention of mother-to-child transmission in UgandaCarole Leach-Lemens | 11 years ago Combination antiretroviral therapy (ART) provided to all pregnant women with HIV who have CD4 cell ......MORE |
HIV infection doesn't generally affect the response to syphilis treatmentMichael Carter | 11 years ago Well-controlled HIV infection does not have a significant impact on the serological response to tre......MORE |
Long-acting integrase inhibitor S/GSK1265744 active against multiple HIV subtypesLiz Highleyman | 11 years ago The integrase inhibitor S/GSK1265744 exhibited potent and prolonged activity against a broad range ......MORE |
Watch for cryptococcal disease in children with HIV, South African doctors warnCarole Leach-Lemens | 11 years ago Clinicians in low- and middle-income countries should give greater consideration to the possibility......MORE |
Dolutegravir combo beats Atripla for effectiveness and tolerabilityLiz Highleyman | 11 years ago The experimental integrase inhibitor dolutegravir combined with abacavir/lamivudine (Kivexa or Epzi......MORE |
Progression of anal neoplasia is common among gay men with HIVLiz Highleyman | 11 years ago Nearly 40% of HIV-positive men with low-grade anal neoplasia may progress to high-grade neoplasia o......MORE |
Sofosbuvir appears safe and effective for HIV/HCV co-infected peopleLiz Highleyman | 11 years ago HIV/HCV co-infected people taking the experimental hepatitis C virus polymerase inhibitor sofosbuvi......MORE |
Symptom screen frequently misses HIV in children and delays treatment, Kenyan study showsCarole Leach-Lemens | 11 years ago Clinical diagnosis of HIV infection in infants performed poorly and resulted in delayed diagnosis w......MORE |
Bacterial translocation is associated with more severe liver fibrosis in HIV/hepatitis C-co-infected peopleMichael Carter | 11 years ago The presence of intestinal bacteria in blood (bacterial translocation) is associated with more seve......MORE |
Integrated analysis shows 'Quad' pill has potent activity with fewer side-effectsLiz Highleyman | 11 years ago An integrated analysis of data from phase II and III trials showed that the 'Quad' single-tablet re......MORE |
Hepatitis B vaccine is effective for up to 15 yearsLiz Highleyman | 11 years ago Nearly all children who received three doses of hepatitis B vaccine achieved immunity, but about 20......MORE |
People with HIV have a poorer response to diabetes therapyMichael Carter | 11 years ago HIV infection is associated with a poorer response to therapy for diabetes, according to US researc......MORE |
Department of Health: separate sexual health services could make some HIV services unviableRoger Pebody | 11 years ago The Department of Health has acknowledged that due to new commissioning and contractual arrangement......MORE |
Long-acting fusion inhibitor albuvirtide looks promising in early studiesLiz Highleyman | 11 years ago A new fusion inhibitor that prevents HIV entry into cells showed potent antiviral activity in early......MORE |
Double trouble: daily function and the impact of old age and HIVMichael Carter | 11 years ago Older age exacerbates the deleterious effect of HIV on daily functioning, investigators from the US......MORE |
Middle-aged people with HIV have a high risk of fallsMichael Carter | 11 years ago Falls are common among middle-aged people with HIV, US investigators report in the online edition o......MORE |
HIV-positive people have heart attacks younger but receive later careLiz Highleyman | 11 years ago People with HIV had heart attacks at a younger age than HIV-negative individuals and were about 50%......MORE |
High rate of infections in people with HIV receiving Bio-Alcamid treatment for facial lipoatrophyMichael Carter | 11 years ago Bio-Alcamid treatment for HIV-related lipoatrophy is associated with a high-rate of infectious comp......MORE |
Few HIV-positive people taking aspirin for the prevention of cardiovascular diseaseMichael Carter | 11 years ago Less than a fifth of people with HIV who qualify for aspirin therapy, for the prevention of cardiov......MORE |
HIV is a risk factor for acquired resistance to key second-line anti-TB drugsMichael Carter | 11 years ago Infection with HIV is a major risk factor for the development of resistance to key second-line anti......MORE |
HIV and antiretroviral therapy increase risk of cardiovascular disease, shows meta-analysisMichael Carter | 11 years ago People with HIV have an increased risk of cardiovascular disease, and the risk is higher still for ......MORE |
Near-perfect adherence needed to suppress cell-associated HIVMichael Carter | 11 years ago Complete adherence to antiretroviral therapy is needed to ensure suppression of cell-associated HIV......MORE |
Chronic hepatitis C virus infection increases risk of death from both liver disease and non-liver-related causesMichael Carter | 11 years ago As well as increasing the risk of death from liver disease, chronic hepatitis C virus infection inc......MORE |
Tentative evidence of treatment-as-prevention efficacy in northern FranceGus Cairns | 11 years ago Physicians at seven HIV clinics in north-eastern France have provided evidence of an association be......MORE |
HPV infection doubles the risk of HIV acquisitionMichael Carter | 11 years ago Human papillomavirus (HPV) infection doubles the risk of HIV acquisition for women, results of a sy......MORE |
International study finds "worrying" levels of XDR-TBMichael Carter | 11 years ago Results of an international study published in The Lancet show that 7% of people receiving second-l......MORE |
Massive increase of hepatitis C incidence in HIV-positive gay men in SwitzerlandMichael Carter | 11 years ago Incidence of hepatitis C virus infections has increased eighteen fold in HIV-positive gay men in Sw......MORE |
Atazanavir/ritonavir more likely to cause kidney stones than other ritonavir-boosted protease inhibitorsMichael Carter | 11 years ago Treatment with ritonavir-boosted atazanavir is associated with a much higher risk of kidney stones ......MORE |
Attachment inhibitor BMS-663068 does well in early study involving HIV-positive peopleMichael Carter | 11 years ago Treatment with BMS-663068, an experimental HIV-1 attachment inhibitor, achieves substantial reducti......MORE |
Male circumcision may not make much difference to overall male HIV incidence in Caribbean contextGus Cairns | 11 years ago A cross-sectional study of men attending a large HIV/STI clinic in San Juan, Puerto Rico, has found......MORE |
"Treatment partners" improve short-term virologic outcomes in those starting HIV therapyMichael Carter | 11 years ago The use of “treatment partners” boosts the chances of achieving an early undetectable viral loa......MORE |
Low levels of innate immune activation and high levels of gut antibodies may protect people from HIVGus Cairns | 11 years ago Several research papers published in the last month have reported strong correlations between speci......MORE |
Glucose metabolism worsens in HIV treatment-experienced taking NRTI-sparing regimensMichael Carter | 11 years ago Italian investigators have found evidence of worsening glucose tolerance in highly treatment-experi......MORE |
Starting HIV treatment reduces risk of kidney diseaseMichael Carter | 11 years ago Starting HIV treatment reduces the risk of chronic kidney disease, US investigators report in the o......MORE |
Patients with pain have poorer engagement with HIV careMichael Carter | 11 years ago Pain in people with HIV is associated with an increased risk of missed appointments, investigators ......MORE |
New US guidelines recommend hepatitis C test for everyone born between 1945 and 1965Michael Carter | 11 years ago Anyone born between 1945 and 1965 should be tested for hepatitis C virus (HCV), according to new gu......MORE |
Detectable viral load and low CD4 cell count are risk factors for shingles in HIV-positive peopleMichael Carter | 11 years ago A CD4 cell count below 500 cells/mm3 and a detectable viral load are risk factors for herpes zoster......MORE |
Three-quarters of clinicians in the US willing to prescribe early HIV treatment for the purpose of preventionMichael Carter | 11 years ago There is an overwhelming consensus among clinicians who prescribe HIV treatment in the US that pati......MORE |
Lower seminal viral load and hints of long-term viral control seen in Thai HIV vaccine recipientsGus Cairns | 11 years ago Men who received the Thai RV144 vaccine who nonetheless became infected with HIV had lover viral lo......MORE |
Religious beliefs don't deter HIV testing or use of antiretrovirals among Africans in LondonMichael Carter | 11 years ago Religious beliefs do not prevent black Africans living in London from accessing HIV testing or star......MORE |
Are antiretroviral switch or simplification studies of benefit for patients?Michael Carter | 11 years ago The attitude of physicians, ethics committees and medical journals to antiretroviral switch and sim......MORE |
Increased rates of unprotected sex among undiagnosed gay men wipe out benefits of diagnosis and HIV treatmentMichael Carter | 11 years ago The ongoing HIV epidemic among gay men in the Netherlands is due to increased rates of unprotected ......MORE |
Newly infected individuals sustaining HIV epidemic in GenevaMichael Carter | 11 years ago Individuals with recent HIV infection are sustaining the epidemic, a Swiss study published in the o......MORE |
Australians find that money problems lead to poorer adherence to HIV therapyMichael Carter | 11 years ago Difficulties meeting pharmacy costs and those incurred travelling for clinic appointments are assoc......MORE |
Could North Africa and the Middle East be a new hotspot for HIV in gay men?Gus Cairns | 11 years ago HIV experts are concerned that the largely Islamic countries of the middle east and north Africa ma......MORE |
Most young Thai MSM define as heterosexual, even if they mainly have sex with menGus Cairns | 11 years ago A large, randomised sample of 21-year-old Thai men, presented at the 19th International AIDS Confer......MORE |
Needs of adolescents with HIV need greater attention, AIDS 2012 hearsCarole Leach-Lemens | 11 years ago Complications of HIV infection among adolescents in resource-poor settings include malnutrition, ch......MORE |
US youth, heterosexual men and African Americans losing out on HIV treatment benefitsGus Cairns | 11 years ago A new study presented at the 19th International AIDS Conference shows that young people, African Am......MORE |
Combination prevention approach could have a big impact on HIV epidemic in ChinaMichael Carter | 11 years ago Increasing rates of HIV testing or expanding the use of antiretroviral therapy will not be enough t......MORE |
Starting HIV treatment reduces risk of tuberculosis, even for patients with higher CD4 cell countsMichael Carter | 11 years ago Starting antiretroviral therapy reduces the risk of tuberculosis for HIV-positive adults in develop......MORE |
What kind of prevention do gay men need?Gus Cairns | 11 years ago As we have already reported, a number of presentations at the 19th International AIDS Conference ex......MORE |
Depending on how it's defined, between 13% and 46% of American gay men report intimate partner violenceRoger Pebody | 11 years ago A study which aimed to produce a definition of intimate partner violence (physical, sexual, or psyc......MORE |
Male partner involvement improves HIV testing during pregnancyKelly Safreed-Harmon | 11 years ago Studies presented at the Nineteenth International AIDS Conference (AIDS 2012) in Washington DC call......MORE |
HIV testing at immunisation clinics: an opportunity to identify women and infants who are falling through the cracks?Kelly Safreed-Harmon | 11 years ago Research from Malawi further strengthens the case for using infant immunisation clinics as a key si......MORE |
Higher CD4 count preserves ability to work and educate childrenCarole Leach-Lemens | 11 years ago A higher CD4 cell count benefits the household economically and is associated with better educatio......MORE |
How to tackle HIV stigma among health care workersMara Kardas-Nelson | 11 years ago Stemming in part from negative associations with the virus itself, and in part from marginalisation......MORE |
Which interventions are best to reduce HIV infections among drug users?Mara Kardas-Nelson | 11 years ago HIV infections among drug users currently make up 30% of new infections globally. Their social marg......MORE |
Changing the way HIV prevention is delivered – a roadmapRoger Pebody | 11 years ago In the last few years there has been a wealth of dramatic data on the efficacy of new HIV preventio......MORE |
Poverty-targeted cash transfers are reducing some HIV risk behavioursMara Kardas-Nelson | 11 years ago Cash transfers to orphans and vulnerable children in Kenya are associated with later onset of sexua......MORE |
BCG vaccination causes immune activation of CD4 T-cells in infantsLesley Odendal | 11 years ago BCG vaccination, routinely given at birth to protect from tuberculosis (TB), causes an immune-activ......MORE |
Raltegravir 800 mg twice daily appears a good alternative to efavirenz for HIV-TB treatmentLesley Odendal | 11 years ago Raltegravir seems to be a suitable alternative to efavirenz for HIV-TB co-infected patients while r......MORE |
Female sex workers have 14 times the risk of having HIV as other womenRoger Pebody | 11 years ago Although researchers and public health organisations in most low and middle income countries have n......MORE |
Once-daily elvitegravir works as well as raltegravir at 96 weeksLiz Highleyman | 11 years ago The investigational HIV integrase inhibitor elvitegravir taken once daily continued to perform as w......MORE |
Cobicistat matches ritonavir as atazanavir boosterLiz Highleyman | 11 years ago The new boosting agent cobicistat works as well as ritonavir (Norvir) as a pharmaco-enhancer or boo......MORE |
Black gay men in the UK almost twice as likely to have HIV as white men, meta-analysis showsRoger Pebody | 11 years ago A new analysis of existing studies on the sexual health of black gay men in the UK has found that d......MORE |
Taking isoniazid preventive therapy for one year reduces the risk of TB in people taking antiretroviral therapyTheo Smart | 11 years ago Twelve months of isoniazid (INH) preventive therapy (IPT) significantly reduced the incidence of al......MORE |
First generic HIV drugs could save US at least $920 million a yearGus Cairns | 11 years ago Even using very conservative estimates of efficacy, using two generic HIV drugs plus one branded on......MORE |
Latest data on HIV cure researchLiz Highleyman | 11 years ago Investigators presented some of the latest HIV cure-related research at a press conference and oral......MORE |
Determine LAM urine antigen TB test is highly cost-effective for use in hospitalised people living with HIVKeith Alcorn | 11 years ago The lateral-flow urine LAM test for tuberculosis – a simple inexpensive strip test for tuberculo......MORE |
Determine LAM urine antigen TB test is highly cost-effective for use in hospitalised people living with HIVTheo Smart | 11 years ago The lateral-flow urine LAM test for tuberculosis – a simple inexpensive strip test for tuberculo......MORE |
Dolutegravir matches raltegravir for people starting treatmentLiz Highleyman | 11 years ago The novel integrase inhibitor dolutegravir worked as well as raltegravir (Isentress) at 48 weeks fo......MORE |
HIV treatment for children: how programmes are improving diagnosis and retentionCarole Leach-Lemens | 11 years ago “It is unacceptable that children at this point in time are not receiving treatment,” René Ekp......MORE |
Does injectable hormonal contraception increase the risk of HIV infection?Gus Cairns | 11 years ago The 19th International AIDS Conference (AIDS 2012) heard further contradictory evidence this week o......MORE |
HIV infection does not compromise multidrug-resistant TB treatment outcomes in BotswanaLesley Odendal | 11 years ago HIV infection did not have an impact on the time it took for multidrug-resistant tuberculosis (MDR-......MORE |
Mobile technologies playing a growing role in HIV care and treatment supportKelly Safreed-Harmon | 11 years ago A number of studies presented at the 19th International AIDS Conference (AIDS 2012) in Washington D......MORE |
In the real world HIV has changed; in the courtroom it is still the 1980sRoger Pebody | 11 years ago In the midwestern American state of Michigan, prosecutors and judges still consider HIV infection t......MORE |
Intellectual property “still a threat,” to antiretroviral access, says panelMara Kardas-Nelson | 11 years ago Patents and intellectual property restrictions continue to affect acess to antiretroviral drugs, pa......MORE |
Community-based support aids retention, adherence and treatment responseLesley Odendal | 11 years ago Patient retention and linkage throughout the cascade of HIV care remains very low, placing the conc......MORE |
Decompensated liver disease more frequent in HIV/HCV co-infected peopleLiz Highleyman | 11 years ago Despite effective antiretroviral therapy, people co-infected with HIV and hepatitis C remain at hig......MORE |
Will MSM use over-the-counter rapid HIV tests to screen sexual partners?Kelly Safreed-Harmon | 11 years ago If men who have sex with men (MSM) have the option of using rapid HIV testing to screen potential s......MORE |
Preventing malaria and diarrhoea delays need for antiretroviral therapyKeith Alcorn | 11 years ago The distribution of long-lasting insecticide-treated nets and water filters to prevent malaria and ......MORE |
Transforming ‘PMTCT programmes into ART programmes’: UNICEF champions lifelong treatment for all HIV-positive pregnant womenKelly Safreed-Harmon | 11 years ago At a session at the 19th International AIDS Conference (AIDS 2012) in Washington DC, UNICEF officia......MORE |
Why Zambians don't test and treatGus Cairns | 11 years ago A study amongst 2443 people in Zambia, recruited from HIV clinics and community organisations, foun......MORE |
Keeping children in school shows impact on HIV risk behaviours in KenyaCarole Leach-Lemens | 11 years ago Providing free school uniforms to enable children to stay in school, in addition to exposing primar......MORE |
South African study finds most women disclose HIV status to family, but far fewer to sexual partnersGus Cairns | 11 years ago A study of HIV-positive people in the high-prevalence area of KwaZulu-Natal in South Africa shows t......MORE |
Dramatic increases in life expectancy in a high-burden HIV setting due to ARV rolloutLesley Odendal | 11 years ago The first evidence of dramatic changes in adult life expectancy in an HIV-endemic region, from indi......MORE |
Population viral load decreases in 'test and treat' study in UgandaLesley Odendal | 11 years ago Positive changes in population-level HIV viral load distribution have been found one year after the......MORE |
Studies highlight complex questions about how communities will respond to PrEPKelly Safreed-Harmon | 11 years ago Two consecutive sessions at the 19th International AIDS Conference (AIDS 2012) in Washington DC hig......MORE |
Novel TB combination regimen shows potent activity in randomised short-term clinical trialKeith Alcorn | 11 years ago A new TB drug, PA-824, showed very potent early bactericidal activity in a randomised 14-day study ......MORE |
Once-daily maraviroc plus boosted atazanavir promising at 96 weeksLiz Highleyman | 11 years ago A NRTI-sparing regimen of maraviroc (Celsentri or Selzentry) plus ritonavir-boosted atazanavir (Rey......MORE |
Adolescent antiretroviral options expandingCarole Leach-Lemens | 11 years ago A range of new antiretroviral drugs are in development for adolescents with HIV, a population which......MORE |
New antiretrovirals for infants and children still neededCarole Leach-Lemens | 11 years ago Promising new formulations of antiretroviral agents including tenofovir, fosamprevanir, dolutegravi......MORE |
Uganda field study finds that HIV treatment has not reduced new infections in couplesGus Cairns | 11 years ago In an uncomfortable finding for advocates of treatment as prevention, a study of heterosexual coupl......MORE |
Hillary Clinton pledges money for vulnerable minorities, reproductive rights, AIDS-free familiesGus Cairns | 11 years ago US Secretary of State Hillary Clinton received a relatively warm reception yesterday at the 19th In......MORE |
'Global health charge' on alcohol and tobacco could cover HIV drug costs in 10 countriesMara Kardas-Nelson | 11 years ago A modest increase in taxes on alcohol and tobacco in countries seriously affected by HIV and TB cou......MORE |
Co-administration of rifampicin and efavirenz does not reduce efavirenz concentrations or efficacyLesley Odendal | 11 years ago Standard dosing of efavirenz, that was not adjusted for patient weight, resulted in therapeutic efa......MORE |
UNITAID commits US$140 million to bring HIV diagnostic technologies to the ‘point of care’Theo Smart | 11 years ago “UNITAID has announced major investment for cutting-edge point-of-care diagnostic tools essential......MORE |
They say we can “end AIDS”, but who will pay for it?Mara Kardas-Nelson | 11 years ago With leaders from Mark Dybul to Michel Sidibé to Hillary Clinton to Anthony Fauci all saying that ......MORE |
Criminalising condom possession by sex workers is a global trendMara Kardas-Nelson | 11 years ago There's nothing new about sex work being illegal – a fact that remains the norm in many countrie......MORE |
Very high incidence of new HIV infections in American black MSM; links with young age and unemploymentRoger Pebody | 11 years ago The largest-ever cohort of black men who have sex with men (MSM) recruited in the United States has......MORE |
Patient tracing and community dispensing of ARVs keep patients in careLesley Odendal | 11 years ago Physical tracing of patients in antiretroviral (ARV) programmes results in a decrease in loss to fo......MORE |
Circumcision taking off in several African countries, but more task-shifting neededGus Cairns | 11 years ago Voluntary medical male circumcision (VMMC) programmes are expanding in several African countries an......MORE |
Syringe exchange expansion in United States would be cost-savingKelly Safreed-Harmon | 11 years ago According to a mathematical analysis presented at the 19th International AIDS Conference (AIDS 2012......MORE |
Providing HIV treatment to employees can lead to big savings for South African companiesKeith Alcorn | 11 years ago Provision of antiretroviral treatment through workplace health schemes in South Africa has the pote......MORE |
Changing epidemiology of opportunistic infections in US: still common in inner citiesLiz Highleyman | 11 years ago Large overall declines in opportunistic infections (OIs) among people with HIV in the US mask conti......MORE |
Peripheral neuropathy in South African children highlights limited ARV choicesCarole Leach-Lemens | 11 years ago Peripheral neuropathy was identified in one-in-four children on HIV treatment in rural Mopani Distr......MORE |
The end of AIDS requires political will, international solidarity, conference toldKeith Alcorn | 11 years ago The world now has the opportunity to end the AIDS epidemic as a result of recent scientific discove......MORE |
What do people living with HIV think about the prospect of a cure?Keith Alcorn | 11 years ago The views of people living with HIV and medical researchers about what makes an HIV cure desirable ......MORE |
Researchers step up efforts to find an HIV cureKeith Alcorn | 11 years ago Scientists launched a road map for research into an HIV cure ahead of the 19th International AIDS C......MORE |
Taking steps to legal reform for men who have sex with men in Africa and the CaribbeanRoger Pebody | 11 years ago We are dealing with two epidemics, the Australian judge Michael Kirby said at a pre-conference meet......MORE |
High levels of adherence reached in two PrEP studies, but resistance cases show need for rigorous testing before prescribingGus Cairns | 11 years ago Two studies of pre-exposure prophylaxis (PrEP) in heterosexuals in Africa, both of which reported s......MORE |
UNAIDS: Africans with HIV more likely to get ARVs than Eastern EuropeansKeith Alcorn | 11 years ago UNAIDS says that international efforts are on target to deliver antiretroviral treatment to 15 mill......MORE |
Chronic hepatitis C infection more than doubles the risk of kidney disease for people with HIVMichael Carter | 11 years ago A detectable hepatitis C viral load is associated with an increased risk of chronic kidney disease ......MORE |
No evidence of an interaction between abacavir and ribavirinMichael Carter | 11 years ago There is no evidence of an interaction between the anti-HIV drug abacavir and the anti-hepatitis C ......MORE |
Late HIV treatment increases risk of death three-fold in UgandaCarole Leach-Lemens | 11 years ago Starting ART at CD4 cell counts below 50 cells/mm3 increased the relative risk of death by approxim......MORE |
Malawi: Routine test offer at immunisation clinics improves early infant HIV diagnosisCarole Leach-Lemens | 11 years ago Integration of testing for early infant diagnosis (EID) was more acceptable and more feasible at a ......MORE |
Insulin resistance is a big risk factor for the progression of liver fibrosis in HIV/HCV co-infected peopleMichael Carter | 11 years ago Insulin resistance is associated with the progression of liver fibrosis in people co-infected with ......MORE |
Should GB virus be used as a therapeutic vaccine to slow HIV progression?Michael Carter | 11 years ago Acquisition of GB virus C (GBV-C) is associated with a 78% reduction in mortality risk for people w......MORE |
Early antiretroviral therapy improves neurodevelopment in HIV-positive infantsMichael Carter | 11 years ago Starting antiretroviral therapy soon after birth improves neurodevelopment in HIV-positive infants,......MORE |
Community-wide initiative boosts HIV testing rates in the Bronx and cuts late diagnosisMichael Carter | 11 years ago A community-wide HIV testing initiative in the Bronx borough of New York City appears to be working......MORE |
HIV home tests – how will they be used?Roger Pebody | 11 years ago This week the OraQuick In-Home HIV Test, which will be sold over the counter and used without medic......MORE |
Uganda: Food insecurity decreases after starting ARTCarole Leach-Lemens | 11 years ago Food insecurity significantly decreased while nutritional status improved over time in adults in Ug......MORE |
Diarrhoea remains a common problem in people with HIVMichael Carter | 11 years ago Diarrhoea remains common in people with HIV and usually has a non-infectious cause, according to a ......MORE |
Detectable viral load and low nadir CD4 cell count increase the risk of heart attack for people with HIVMichael Carter | 11 years ago A detectable viral load, a low nadir CD4 cell count and an elevated CD8 cell count are associated w......MORE |
Low bone density present in young men taking HIV therapyMichael Carter | 11 years ago HIV infection in young men is associated with reduced bone mineral density, US investigators report......MORE |
Pregnancy rate among HIV-positive women in the UK has increased significantlyMichael Carter | 11 years ago The pregnancy rate among HIV-positive women in the UK increased significantly between 2000 and 2009......MORE |
Routine, non-targeted HIV testing feasible and acceptable in UK, study concludesGus Cairns | 11 years ago A London-based study in which HIV tests were offered in a non-targeted manner to as many patients a......MORE |
Four-class, five-drug regimen given to monkeys shows signs of producing long-term viral load reductions off treatmentGus Cairns | 11 years ago An animal study (Shytaj) in which standard antiretroviral therapy (ART) was intensified by adding i......MORE |
Second-line HIV therapy effective and durable in South Africa, and adherence support could improve rates of viral suppressionMichael Carter | 11 years ago Second-line antiretroviral therapy in South Africa achieves durable viral suppression in three-quar......MORE |
Vaginal discharge is a poor way of diagnosing STIs, with asymptomatic infections associated with an increased risk of HIVMichael Carter | 11 years ago Symptoms are a poor way of detecting discharge-causing sexually transmitted infections (STIs) in wo......MORE |
The road to PrEP: trials, regulation and roll-outGus Cairns | 11 years ago Within the next three years, up to 33,000 people may take part in 22 different studies worldwide to......MORE |
The road to PrEP: trials, regulation and rolloutGus Cairns | 11 years ago Within the next three years up to 33,000 people may take part in 22 different studies worldwide to ......MORE |
US health surveillance director: How can we use treatment to strengthen prevention?Gus Cairns | 11 years ago “Now, more than ever, it is possible to change the course of the HIV epidemic, by combining HIV p......MORE |
Booster dose of measles vaccine achieves high levels of protection for children taking effective HIV treatmentMichael Carter | 11 years ago A booster dose of the measles vaccine produces protective antibody responses and immunologic memory......MORE |
Active injecting drug users must be provided with adherence support when they start HIV therapyMichael Carter | 11 years ago Chances of achieving an undetectable viral load are equally poor for patients who inject heroin, co......MORE |
HIV/hepatitis C co-infection increases risk of hip fractureMichael Carter | 11 years ago Co-infection with HIV and hepatitis C is associated with an increased risk of hip fracture, US inve......MORE |
UK data suggests that treatment isn’t curbing the gay HIV epidemic – because of undiagnosed infectionsRoger Pebody | 11 years ago In the UK, the majority of the HIV-positive gay and bisexual men who are likely to transmit HIV rem......MORE |
UK data suggest that treatment isn’t curbing the gay HIV epidemic – because of undiagnosed infectionsRoger Pebody | 11 years ago In the UK, the majority of the HIV-positive gay and bisexual men who are likely to transmit HIV rem......MORE |
Is treatment as prevention ready to roll out, or do we need to know more?Keith Alcorn | 11 years ago Major randomised studies of the impact of antiretroviral treatment expansion on new infections are ......MORE |
If people who need HIV drugs aren’t getting them now, why should the prevention benefit of treatment be the reason that the drugs become available?Roger Pebody | 11 years ago The issue of ‘treatment as prevention’ raises a number of ethical issues, Richard Ashcroft, pro......MORE |
Study shows that use of darunavir/ritonavir and etravirine in HIV treatment as a prevention method is biologically plausibleMichael Carter | 11 years ago A pharmacokinetic study suggests that ritonavir-boosted darunavir (Prezista) and etravirine (Intele......MORE |
Doctors in Europe and the US disagree over the pace of liver fibrosis in men co-infected with HIV and hepatitis CMichael Carter | 11 years ago Doctors in Europe and the US have conflicting opinions about the pace of liver fibrosis in HIV-posi......MORE |
World Health Organization sets out route map for scale-up of treatment as preventionKeith Alcorn | 11 years ago The number of people eligible for antiretroviral treatment will grow by around six million as a res......MORE |
Health educators should work with the inner contradictions that 'barebackers' expressRoger Pebody | 11 years ago When asked by researchers to talk about their practice of having ‘bareback’ sex (unprotected an......MORE |
Big delays in switching to second-line ART in South AfricaCarole Leach-Lemens | 11 years ago Virologic rebound occurred in only one in six patients during the first 18 months of antiretroviral......MORE |
Hepatitis B is a major health issue for migrants in the USMichael Carter | 11 years ago Between 1.04 million and 1.61 million migrants now resident in the US have chronic hepatitis B infe......MORE |
Rapid CD4 cell testing as part of HIV testing and counselling increases chances that people will be successfully linked to careMichael Carter | 11 years ago The use of rapid, point-of-care CD4 cell tests increases the chances that people diagnosed with HIV......MORE |
Study identifies characteristics of gay men who may be suitable for intermittent PrEPMichael Carter | 11 years ago Older, better-educated gay men who use sexual networking sites and have sex outside the context of ......MORE |
Poor adherence may be an obstacle to intermittent PrEPMichael Carter | 11 years ago Adherence to intermittent pre-exposure prophylaxis (PrEP) is significantly poorer than adherence to......MORE |
Significant worsening of sexual health in England in 2011: gay men and young heterosexual adults had high rates of STIsMichael Carter | 11 years ago There has been a significant worsening in the sexual health of gay and other men who have sex with ......MORE |
Gay and bisexual men who inject drugs more likely to have HIV than other men who inject drugsMichael Carter | 11 years ago HIV prevalence is four times higher in gay and bisexual men who inject drugs, compared to heterosex......MORE |
HIV prevalence beginning to fall in South African childrenCarole Leach-Lemens | 11 years ago HIV prevalence fell sharply among children admitted to one of South Africa’s largest hospitals in......MORE |
Rapid CD4 cell count performs well in HIV care and is highly acceptable to UK patientsMichael Carter | 11 years ago A finger-prick test that provides CD4 cell count results within an average of 30 minutes is as accu......MORE |
Starting HIV treatment with a CD4 cell count below 350 associated with a key marker of cardiovascular riskMichael Carter | 11 years ago Starting HIV treatment with a CD4 cell count below 350 cells/mm3 may increase the long-term risk of......MORE |
HIV treatment breaks lead to drug resistance in the female genital tractMichael Carter | 11 years ago Antiretroviral treatment interruptions of 48 hours or more are associated with the emergence of res......MORE |
Diabetes increases risk of chronic kidney disease for people with HIV: effect greater than for either disease aloneMichael Carter | 11 years ago Diabetes increases the risk of the progression of chronic kidney disease for patients with HIV, US ......MORE |
Kenyan heterosexual couples want a choice of antiretroviral prevention methodsMichael Carter | 11 years ago Approximately 40% of HIV-positive people in a stable relationship with an HIV-negative person in Ke......MORE |
NICE says sperm washing is no safer than effective treatment and timed intercourseRoger Pebody | 11 years ago Draft UK guidance on fertility treatment says that sperm washing may no longer be necessary for cou......MORE |
Antiretroviral therapy may be stabilising HIV epidemic in Danish gay menMichael Carter | 11 years ago The use of antiretroviral treatment appears to have stabilised the HIV epidemic in Danish gay men, ......MORE |
Hepatitis C testing rate low and knowledge of the infection poor in the US "baby boomer" generationMichael Carter | 11 years ago Only a quarter of US individuals in the generation most likely to have hepatitis C have ever been t......MORE |
Hepatitis C testing rate low and knowledge of the infection poor in the US 'baby boomer' generationMichael Carter | 11 years ago Only a quarter of US individuals in the generation most likely to have hepatitis C have ever been t......MORE |
HIV infection is an independent risk factor for strokeMichael Carter | 11 years ago HIV infection is associated with an increased risk of stroke, US research published in the online e......MORE |
HIV infections are being missed in UK patients with suspected glandular feverMichael Carter | 11 years ago HIV infections in patients with suspected glandular fever are often missed, investigators from sout......MORE |
South Africa exceeds 2007-11 treatment targets by 50%Carole Leach-Lemens | 11 years ago South Africa exceeded national targets for new patients starting antiretroviral treatment (ART) by ......MORE |
US regulators set to approve HIV home-testing kitRoger Pebody | 11 years ago HIV home testing is soon likely to become legal in the United States, following a unanimous vote in......MORE |
Standard hepatitis C therapy improves insulin resistance in HIV/hepatitis C co-infected patientsMichael Carter | 11 years ago Treatment with pegylated interferon and ribavirin is associated with lasting improvements in insuli......MORE |
BI 201335 & BI 207127 and ribavirin shows good efficacy, including hepatitis C patients with cirrhosisLiz Highleyman | 11 years ago An interferon-free regimen of the hepatitis C virus (HCV) protease inhibitor BI 201335, the non-nuc......MORE |
US regulators vote for approval of PrEP by large majorityGus Cairns | 11 years ago The US Food and Drug Administration (FDA) took a decisive step yesterday towards approving the use ......MORE |
US regulators vote for approval of PrEP by large majorityGus Cairns | 11 years ago The US Food and Drug Administration (FDA) took a decisive step yesterday towards approving the use ......MORE |
Canadian cohort shows viral suppression most likely with atazanavir/ritonavir-based HIV treatment after 6 monthsMichael Carter | 11 years ago Antiretroviral therapy based on the ritonavir-boosted protease inhibitor atazanavir (Reyataz) was m......MORE |
Ribavirin dose reduction is effective for managing anaemia in patients using boceprevir or telaprevirLiz Highleyman | 11 years ago Reducing the dose of ribavirin and adding erythropoietin are both good options for managing anaemia......MORE |
HIV treatment reduces incidence of pre-cancerous cervical lesions and promotes their regressionMichael Carter | 11 years ago Antiretroviral therapy is associated with a reduced incidence of pre-cancerous cervical lesions in ......MORE |
Promising findings for therapeutic hepatitis C vaccine TG4040Liz Highleyman | 11 years ago An investigational hepatitis C virus (HCV) therapeutic vaccine significantly improved the likelihoo......MORE |
Depression and pegylated interferon: doctors look at screening strategies and treatmentMichael Carter | 11 years ago Patients with hepatitis C should be carefully evaluated for symptoms of depression before and durin......MORE |
Black race and depression associated with poorer adherence to HIV treatmentMichael Carter | 11 years ago African American patients have significantly poorer adherence to HIV therapy compared to other raci......MORE |
Co-infection with hepatitis C increases mortality risk by 50% for patients with AIDSMichael Carter | 11 years ago Co-infection with hepatitis C increases the risk of death for patients with AIDS by 50%, according ......MORE |
Unplanned treatment interruptions involve a greater risk of virological failure than missing occasional dosesMichael Carter | 11 years ago Unstructured treatment interruptions – rather than missed doses of medication – involve a gre......MORE |
Poor knowledge of HIV PrEP among MSM in Beijing, but high interestMichael Carter | 11 years ago Few gay and other men who have sex with men (MSM) in Beijing have heard of pre-exposure prophylaxis......MORE |
Only 20% of US HIV-positive people have high levels of engagement with specialist HIV careMichael Carter | 11 years ago Only a fifth of HIV-positive people in the United States are fully engaging in specialist HIV care,......MORE |
Unmet basic subsistence needs is the most important factor affecting health of poor HIV-positive menMichael Carter | 11 years ago An inability to provide for the most basic needs of life is the biggest predictor of poor physical ......MORE |
Brivanib did not improve overall liver cancer survival, but did show anti-tumour activityLiz Highleyman | 11 years ago The experimental cancer drug brivanib did not lengthen overall survival for patients with hepatocel......MORE |
GS-7977 with interferon/ribavirin cures most treatment-naive hepatitis C patients in 12 weeksLiz Highleyman | 11 years ago Adding GS-7977 to pegylated interferon and ribavirin for 12 weeks led to a sustained response rate ......MORE |
Reductions in visceral fat during tesamorelin therapy associated with improvements in key metabolic markersMichael Carter | 11 years ago Reductions in visceral adiposity achieved with tesamorelin therapy are associated with improvements......MORE |
Chronic hepatitis B infection associated with twice the risk of liver-related death compared to hepatitis CMichael Carter | 12 years ago The risk of death due to liver disease is twice as high for patients with chronic hepatitis B infec......MORE |
People with TB and HIV in South Africa face a double stigmaRoger Pebody | 12 years ago People who have both tuberculosis (TB) and HIV experience “a unique and overlapping double stigma......MORE |
Incidence of hepatitis C re-infection and clearance may be understimatedMichael Carter | 12 years ago The incidence of hepatitis C re-infection among high-risk individuals who have spontaneously cleare......MORE |
Untreated HIV infection is associated with higher blood alcohol levelsMichael Carter | 12 years ago Starting HIV treatment is associated with reductions in blood alcohol levels, results of a small pi......MORE |
Treatment switches becoming less common, side-effects still the key reason for switchingRoger Pebody | 12 years ago The number of people who need to change their antiretroviral drug regimen has declined significantl......MORE |
Abbott interferon-free HCV combinations show early promise in untreated patientsKeith Alcorn | 12 years ago Two interferon-free antiviral regimens being developed by Abbott showed high hepatitis C cure rates......MORE |
Boceprevir a useful option for patients who did not respond to earlier course of hepatitis C therapyMichael Carter | 12 years ago A regimen of boceprevir with pegylated interferon and ribavirin achieved cure rates of between 40 a......MORE |
Adding TMC435 boosts response for difficult-to-treat hepatitis C patientsLiz Highleyman | 12 years ago A combination of TMC435 – also known as simeprevir – plus pegylated interferon and ribavirin ......MORE |
Hepatitis C drug alisporivir is effective, but pancreatitis a concernLiz Highleyman | 12 years ago Alisporivir (formerly Debio 025) in interferon-free combinations cured more than 80% of patients wi......MORE |
PrEP acceptable to UK gay men, studies findRoger Pebody | 12 years ago Pre-exposure prophylaxis (PrEP) would be an acceptable HIV prevention strategy for large numbers of......MORE |
Telaprevir and boceprevir show high rate of serious side-effects in hepatitis C patients with urgent need of treatmentKeith Alcorn | 12 years ago A real-world study of new hepatitis C protease inhibitors in the group of patients who have been to......MORE |
Hepatitis C meds GS-7977, daclatasvir and asunaprevir look good in interferon-free combosLiz Highleyman | 12 years ago Most previously untreated people with chronic hepatitis C achieved an early cure with an all-oral c......MORE |
Interferon-lambda as effective as alpha but with much better safety profile in hepatitis CMichael Carter | 12 years ago A new form of pegylated interferon is associated with significantly fewer side-effects than the sta......MORE |
Depression associated with socioeconomic difficulties and poor virological outcomes in UK HIV patientsRoger Pebody | 12 years ago A quarter of people with HIV in the UK have a depressive disorder, according to an ongoing study ......MORE |
Financial incentives and motivational interviewing being used to improve adherence in young peopleRoger Pebody | 12 years ago St Mary’s Hospital in London is testing the use of cash incentives, in combination with motivat......MORE |
Half of women at east London HIV clinic have experienced intimate partner violenceRoger Pebody | 12 years ago Half the female patients at the HIV clinic in Homerton Hospital, east London, have suffered intimat......MORE |
No significant link between injectable contraceptives and HIV risk, but questions still remainGus Cairns | 12 years ago Two studies presented at the International Microbicides Conference this week failed to completely d......MORE |
No more single-theme conferences: global HIV prevention conference plannedGus Cairns | 12 years ago The International Microbicides Conference held in Sydney this week will be the last of its kind, de......MORE |
Douching does not seem to increase STI riskGus Cairns | 12 years ago Neither rectal douching nor vaginal washing appear to be as significantly associated with sexually ......MORE |
Gay partners' HIV transmission study due to start, despite practical barriersGus Cairns | 12 years ago A large study looking at HIV infections in gay men who are within long-term relationships with HIV......MORE |
Improved health, wish for normal life, main reason for loss to follow-up in Ugandan HIV patientsCarole Leach-Lemens | 12 years ago Wanting to return to a ‘normal’ life after having experienced an improvement in health on HIV t......MORE |
Disposable device that enables circumcision without stitches safely detaches without need for removal by healthcare staffMichael Carter | 12 years ago A device that allows for circumcision without the need for stitches often detaches spontaneously if......MORE |
Contraceptive requirement may have compromised FEM-PrEP studyGus Cairns | 12 years ago A requirement that all participants take hormonal contraceptives may have been what led to the disa......MORE |
Does CMV underlie the increased risk of cardiovascular disease in patients with HIV?Michael Carter | 12 years ago Cytomegalovirus (CMV) antibody levels are associated with some important markers of vascular diseas......MORE |
30% decline in deaths after expansion of ART access in rural KenyaCarole Leach-Lemens | 12 years ago Expansion of HIV programme services over a five year period in a high HIV prevalence area of rural ......MORE |
Low CD4 cell count and older age associated with increased risk of TB after starting HIV therapyMichael Carter | 12 years ago People with HIV reduce their overall risk of tuberculosis (TB) by starting antiretroviral therapy, ......MORE |
Treatment with a ritonavir-boosted protease inhibitor during pregnancy increases risk of preterm deliveryMichael Carter | 12 years ago Antiretroviral therapy during pregnancy is associated with an increased risk of premature delivery,......MORE |
Discordance between CD4 cell count and percentage associated with markers of liver disease in HIV/hepatitis C co-infected peopleMichael Carter | 12 years ago Discordance between CD4 cell count and CD4 cell percentage in people co-infected with HIV and hepat......MORE |
Liver fibrosis increases risk of discordance in CD4 cell count and percentage in HIV-positive peopleMichael Carter | 12 years ago Liver fibrosis is associated with discordance between CD4 cell counts and percentages in HIV-positi......MORE |
Hepatitis C infections now twice as likely in HIV+ gay men as in injecting drug users, Swiss study findsGus Cairns | 12 years ago The annual incidence of hepatitis C infection in gay men with HIV is now nearly twice that seen in ......MORE |
Hepatitis C infection now twice as common in HIV+ gay men as injecting drug users, Swiss study findsGus Cairns | 12 years ago Twice as many HIV-positive gay men are now being infected with hepatitis C as HIV-positive injectin......MORE |
Investing in national TB programmes has a real impact on burden of the diseaseMichael Carter | 12 years ago Investment in national tuberculosis (TB) programmes improves TB detection rates, a study published ......MORE |
A low CD4 cell count, weight and haemoglobin can identify which HIV-positive patients are more likely to have undiagnosed TBMichael Carter | 12 years ago Undiagnosed tuberculosis (TB) is common among patients receiving routine HIV care in South Africa, ......MORE |
HIV is an independent risk factor for lung cancerMichael Carter | 12 years ago Infection with HIV is an independent risk factor for lung cancer, according to the results of a lar......MORE |
Tenofovir use during pregnancy doesn't affect infant size or weight at birth, but may by one year of ageMichael Carter | 12 years ago Use of tenofovir during pregnancy does not have an adverse impact on infant weight or size at birth......MORE |
Many men with undetectable HIV in blood still have low levels in their semen, studies findGus Cairns | 12 years ago A study of 101 gay men at the Fenway Health HIV clinic in Boston, USA (Politch) has found that a qu......MORE |
Kenya: Only 4% of pregnant women started ART within 6 months of diagnosisCarole Leach-Lemens | 12 years ago Only 4% of HIV-positive pregnant women estimated as needing ART for their own health (CD4 cell coun......MORE |
Limited provision of TB services in prison in countries receiving Global Fund grantsMichael Carter | 12 years ago Only 50% of countries in receipt of grants from the Global Fund to Fight AIDS, Tuberculosis and Mal......MORE |
New US treatment guidelines recommend antiretroviral treatment for all people with HIVKeith Alcorn | 12 years ago Newly updated US antiretroviral treatment guidelines are recommending antiretroviral treatment for ......MORE |
Cogntive function improves throught the first year of HIV therapyMichael Carter | 12 years ago Cognitive function continues to improve up to one year after starting antiretroviral therapy, accor......MORE |
Cognitive function improves through the first year of HIV therapyMichael Carter | 12 years ago Cognitive function continues to improve up to one year after starting antiretroviral therapy, accor......MORE |
How is HIV prevention policy made in Tanzania and why do structural interventions lose out?Roger Pebody | 12 years ago Far from being primarily driven by scientific evidence, decisions about spending priorities for HIV......MORE |
Antiretroviral rollout provides a model for efforts to expand hepatitis C treatment and care in resource-limited settingsMichael Carter | 12 years ago The rollout of antiretroviral therapy in resource-limited settings provides a model for efforts to ......MORE |
HIV doesn't increase the risk of insomniaMichael Carter | 12 years ago Many HIV-positive patients have insomnia or daytime sleepiness, investigators from the US military ......MORE |
Low CD4 cell count increases risk of severe forms of extra-pulmonary TBMichael Carter | 12 years ago A low CD4 cell count is associated with more severe forms of extra-pulmonary tuberculosis (TB), US ......MORE |
Results of tests for recent HIV infection can be safely given to patientsRoger Pebody | 12 years ago Results from the Recent Infection Testing Algorithm (RITA) can be discussed with newly-diagnosed pa......MORE |
Vitamin D deficiency increases risk of 'silent' cardiovascular disease in HIV-positive African AmericansMichael Carter | 12 years ago Vitamin D deficiency is associated with “silent” coronary artery disease, according to the resu......MORE |
Genital warts a marker for increased risk of anogenital cancers, cancers of the head and neck as well as some other malignanciesMichael Carter | 12 years ago Infection with genital warts is associated with an increased risk of ano-genital cancers, malignanc......MORE |
Guidelines developed to help boost rates of entry into HIV care, retention in care and levels of adherenceMichael Carter | 12 years ago New guidelines have been developed to improve the entry of patients into specialist HIV care and as......MORE |
Serosorting does help prevent HIV – up to a pointGus Cairns | 12 years ago An meta-analysis of HIV-negative gay men’s sexual behaviour and HIV incidence rate in four HIV pr......MORE |
Treatment as prevention is starting to work in parts of AfricaGus Cairns | 12 years ago A longitudinal study from KwaZulu Natal province in South Africa is the first study from the global......MORE |
Poor adherence to HIV PEP after sexual assaultMichael Carter | 12 years ago Adherence to HIV post-exposure prophylaxis (PEP) among victims of sexual assault is poor, according......MORE |
Thibela TB: Community-wide IPT did not improve TB control in South Africa’s mines at the population levelTheo Smart | 12 years ago Giving a six- to nine-month course of isoniazid preventive therapy (IPT) at a ‘community-wide lev......MORE |
Uncontrolled HIV linked to faster lung function declineLiz Highleyman | 12 years ago People with detectable HIV viral load and advanced immune deficiency are likely to experience great......MORE |
Statins may slightly reduce non-AIDS events and deathLiz Highleyman | 12 years ago Cholesterol-lowering statin drugs showed a trend toward lowering the risk of non-AIDS events and de......MORE |
Metformin reduces artery plaque in HIV-positive people with metabolic syndromeLiz Highleyman | 12 years ago The diabetes drug metformin can help stall progression of calcium buildup in the coronary arteries ......MORE |
Studies look at interactions between new hepatitis C drugs and HIV antiretroviralsLiz Highleyman | 12 years ago Drug-drug interactions between direct-acting antiviral agents for hepatitis C and some antiretrovir......MORE |
Elvitegravir Quad pill matches efavirenz and atazanavir combosLiz Highleyman | 12 years ago The Quad single-tablet regimen, an all-in-one pill containing the experimental integrase inhibitor ......MORE |
Early infant diagnosis for HIV: is it taking place early enough?Theo Smart | 12 years ago Current early infant diagnosis (EID) protocols may need to be revised in the light of current WHO g......MORE |
KS in Africa: people with low CD4 counts still at risk despite ARTCarole Leach-Lemens | 12 years ago The incidence of Kaposi’s Sarcoma (KS) among HIV-infected adults on ART in Uganda and Kenya remai......MORE |
Protease inhibitor not superior to NNRTI in sub-Saharan AfricaCarole Leach-Lemens | 12 years ago Protease inhibitor-based treatment did not result in superior rates of viorologic suppression after......MORE |
HIV brain impairment: who gets it, and why?Gus Cairns | 12 years ago A number of papers at the 19th Conference on Retroviruses and Opportunistic Infections presented ad......MORE |
Cancers in people with HIV: who gets them, and which ones?Keith Alcorn | 12 years ago A very low CD4 count in the past, and a history of smoking, are the most consistent risk factors to......MORE |
Circumcision reduces HIV incidence in Ugandan men and herpes prevalence in South AfricansGus Cairns | 12 years ago The Nineteenth Conference on Retroviruses and Opportunistic Infections heard this week that a tenfo......MORE |
Superinfection: second HIV infections happen as often as first onesGus Cairns | 12 years ago Two studies of people with HIV in Rakai, Uganda and Mombasa, Kenya presented at the 19th Conference......MORE |
Novel integrase inhibitor dolutegravir still potent at 96 weeksLiz Highleyman | 12 years ago The next generation integrase inhibitor dolutegravir maintains viral suppression and remains safe a......MORE |
Controversy regarding strategic treatment interruptions in young children who start ART during infancyTheo Smart | 12 years ago Two studies generated conflicting data and rather mixed messages about whether it is safe or advisa......MORE |
Tenofovir pro-drug GS-7340 shows good safety and efficacy in short studyLiz Highleyman | 12 years ago GS-7340, a pro-drug of tenofovir that reaches higher concentrations in cells, had superior efficacy......MORE |
When does viral load testing add value in sub-Saharan Africa?Keith Alcorn | 12 years ago Routine viral load testing did not catch failure of first-line treatment earlier than discretionary......MORE |
PEPFAR funding linked to lower death rate from all causes in AfricaKeith Alcorn | 12 years ago PEPFAR funding for HIV programmes lowered the risk of death in countries receiving funds by around ......MORE |
Tenofovir rectal microbicide safe; may have direct effect on tissues as well as virusGus Cairns | 12 years ago A gel containing 1% tenofovir formulated specifically for rectal use was much better tolerated than......MORE |
A new patient zero? Researchers may have spotted animal-to-human immunodeficiency virus transferGus Cairns | 12 years ago A group of scientists working in Ivory Coast may have discovered a case of infection of a human wit......MORE |
Lipoatrophy common in children receiving d4T in South AfricaCarole Leach-Lemens | 12 years ago Exposure to d4T (stavudine) among young children in sub-Saharan Africa remains the greatest risk fa......MORE |
Keeping mothers in care: the real-world challenge for PMTCT programmesKeith Alcorn | 12 years ago Implementing new recommendations for prevention of mother-to-child transmission (PMTCT) using antir......MORE |
Lopinavir/ritonavir cuts malaria risk in children with HIVCarole Leach-Lemens | 12 years ago HIV-infected children in Tororo, Uganda, an area of high malaria transmission, on a lopinavir/riton......MORE |
GS-7977 plus ribavirin rapidly suppresses HCV but most patients relapseLiz Highleyman | 12 years ago An interferon-free combination of the experimental polymerase inhibitor GS-7977 plus ribavirin pote......MORE |
Telaprevir and boceprevir boost sustained response rates for HIV/HCV coinfectedLiz Highleyman | 12 years ago Adding a first-generation hepatitis C virus (HCV) protease inhibitor to pegylated interferon/ribavi......MORE |
Hormonal contraception and HIV risk in women: more evidence but uncertainty remainsKeith Alcorn | 12 years ago Injectable hormonal contraception may raise the risk of HIV infection for women, but it does not ap......MORE |
Once-a-month HIV drug maintains good levels for prevention; few side-effects so farGus Cairns | 12 years ago The first trial in humans of an injectable, once-a-month formulation of an HIV drug has found that ......MORE |
Four doses of PrEP a week may be enough to protectGus Cairns | 12 years ago Further testing of drug levels in the blood and immune cells of gay men participating in the iPrEx ......MORE |
A tale of two trials: how adherence is everything in PrEPGus Cairns | 12 years ago Adherence makes all the difference to the efficacy of pre-exposure prophylaxis (PrEP), the 19th Con......MORE |
FDA updates guidance for use of HIV and hepatitis C protease inhibitors with statinsMichael Carter | 12 years ago Medicine regulatory authorities in the US have updated their recommendations concerning possible in......MORE |
World Health Organization issues new policy to step up TB/HIV effortsKeith Alcorn | 12 years ago Around 910,000 lives were saved between 2005 and 2010 as a result of closer working relationships b......MORE |
Will treatment as prevention make a difference to the UK epidemic? Health promoters respondRoger Pebody | 12 years ago Whereas in previous years, delegates at the CHAPS conference of gay men’s health promoters have d......MORE |
PrEP needs more study before being provided, UK physicians concludeGus Cairns | 12 years ago A position statement by the British HIV Association (BHIVA) and the British Association for Sexual ......MORE |
Hepatitis C subtype-1b and carriage of IL28B gene associated with improved treatment responses in HIV-co-infected patientsMichael Carter | 12 years ago Hepatitis C treatment responses in patients co-infected with HIV are better in patients infected wi......MORE |
HIV treatment isn't a risk factor for liver dysfunction, but HIV infection isMichael Carter | 12 years ago Infection with HIV is associated with an increased risk of hepatic dysfunction, and death related t......MORE |
HIV treatment to be free for undocumented migrants and non-UK citizensRoger Pebody | 12 years ago The Department of Health has announced that it will soon make HIV treatment free for all who need i......MORE |
'Social networks' may explain high prevalence of MRSA colonization seen in patients with HIVMichael Carter | 12 years ago Infection with HIV per se does not increase the risk of colonisation with community-associated MRSA......MORE |
Fat accumulation linked to cognitive impairment in patients with HIVMichael Carter | 12 years ago Central fat accumulation is associated with an increased risk of neurocognitive impairment for HIV-......MORE |
Second-line treatment failure most often due to poor adherence in low and middle-income countriesCarole Leach-Lemens | 12 years ago Poor adherence rather than drug resistance appears more likely to be the cause of virological failu......MORE |
Substantial number of HIV infections in UK-born patients acquired abroadMichael Carter | 12 years ago A substantial number of HIV infections in UK-born individuals were acquired abroad, investigators r......MORE |
Hepatitis C protease inhibitor therapy cost effective in some circumstancesMichael Carter | 12 years ago First-line hepatitis C therapy which includes a protease inhibitor can be cost-effective, investiga......MORE |
Hepatitis C protease inhibitor therapy cost-effective in some circumstancesMichael Carter | 12 years ago First-line hepatitis C therapy which includes a protease inhibitor can be cost-effective, investiga......MORE |
Hepatitis C surpasses HIV as a cause of death in the USMichael Carter | 12 years ago Deaths in the US due to hepatitis C now exceed those caused by HIV, according to research published......MORE |
Severe nevirapine rash linked to slow clearance of drugCarole Leach-Lemens | 12 years ago The risk of severe rash when taking the antiretroviral drug nevirapine is greater in women who clea......MORE |
Australian gay men cautious about PrEP; most in need are the most interestedGus Cairns | 12 years ago Only just over one in four Australian gay men in a recent scientific survey described themselves as......MORE |
UK guidelines on treatment of HIV in pregnancy give green light to efavirenzKeith Alcorn | 12 years ago New UK draft guidelines on the management of HIV infection in pregnant women recommend that efavire......MORE |
High prevalence of trauma among HIV-positive women in the USMichael Carter | 12 years ago Almost a third of HIV-positive women in the US have recent post-traumatic stress disorder and 55% h......MORE |
Half of all new HIV transmissions in US may originate in undiagnosed individualsMichael Carter | 12 years ago Almost half of all new HIV transmissions in the US originate in individuals who are unaware that th......MORE |
HIV treatment reduces risk of fracturesMichael Carter | 12 years ago Treatment with antiretroviral drugs reduces the risk of low-impact fractures, according to a case-c......MORE |
Tenofovir associated with increased risk of kidney diseaseMichael Carter | 12 years ago Treatment with tenofovir is associated with a modestly increased risk of three key markers of kidne......MORE |
Cotrimoxazole prophylaxis reduces death rate by almost 60% in adults taking ART in low and middle-income countriesCarole Leach-Lemens | 12 years ago Cotrimoxazole significantly reduces death among adults on ART in low and middle-income countries, a......MORE |
Cotrimoxazole prophylaxis is cost-effective for people starting ART in sub-Saharan AfricaCarole Leach-Lemens | 12 years ago Achieving full coverage of cotrimoxazole prophylaxis during the first six months of antiretroviral ......MORE |
Use of some anti-HIV drugs during pregnancy linked to cleft lip and palate; investigators urge cautious interpretation of resultsMichael Carter | 12 years ago US investigators have identified a possible association between the use of antiretroviral therapy d......MORE |
Increased risk of anal cancer for all groups with HIVMichael Carter | 12 years ago Gay men are not the only group of HIV-positive patients who have an increased risk of anal cancer, ......MORE |
Professional tattooing in sterile environment not associated with risk of hepatitis CMichael Carter | 12 years ago Tattooing or body piercing in professional parlours is not associated with an increased risk of inf......MORE |
New BHIVA guidelines recommend discussion with all patients on potential of HIV treatment to protect sexual partnersKeith Alcorn | 12 years ago The British HIV Association (BHIVA) today recommends that doctors should discuss the evidence for t......MORE |
US CDC recommends HPV vaccine for young menKeith Alcorn | 12 years ago Young men and adolescent boys between the ages of 11 and 21 should be vaccinated against human papi......MORE |
Gardasil protects against recurrence of pre-cancerous anal lesions in HIV-negative gay menMichael Carter | 12 years ago The genital wart vaccine Gardasil significantly reduces the risk of high-grade pre-cancerous anal l......MORE |
For patients with HIV viral load is key in immune response to yellow fever vaccineMichael Carter | 12 years ago Viral load is the only factor associated with a poorer antibody response to the yellow fever vaccin......MORE |
Contraception in HIV prevention trials: injectable hormonal methods more effective?Carole Leach-Lemens | 12 years ago Women using injectable (hormonal) contraceptives had a significantly lower rate of pregnancy compar......MORE |
Men who have sex with men may now be the highest-risk group for HIV in Africa, IAVI study suggestsGus Cairns | 12 years ago Men who have sex with men may now be at considerably higher risk of acquiring HIV than other at-ris......MORE |
HIV care providers in US struggling to cope with rising patient numbersMichael Carter | 12 years ago HIV doctors in the US are struggling to meet the demands of a rising patient caseload, according to......MORE |
Quarter of men resume sex before wounds from circumcision fully healed in Zambian studyMichael Carter | 12 years ago Approximately a quarter of men undergoing circumcision resume sexual activity before their wounds h......MORE |
Raltegravir/Truvada HIV PEP regimen well tolerated with no infections after its useMichael Carter | 12 years ago Raltegravir could have a “useful” role in HIV post-exposure prophylaxis, according to investiga......MORE |
For study participants, PrEP was an opportunity to save their relationshipRoger Pebody | 12 years ago Seeking to understand why adherence to pre-exposure prophylaxis (PrEP) was extremely high in a stud......MORE |
Majority of HIV-positive patients in US not receiving regular medical careMichael Carter | 12 years ago Only 45% of HIV-positive patients in the US are receiving regular medical monitoring, research publ......MORE |
Hormonal contraception and HIV risk: no increased risk in South African cohortCarole Leach-Lemens | 12 years ago Of the 270 South African women from a cohort of 5567 who became HIV-infected, use of hormonal contr......MORE |
Rapid HIV test performance poorer with oral fluid than blood, especially when prevalence is lowRoger Pebody | 12 years ago The performance of OraQuick, a widely used rapid point-of-care test for HIV diagnosis, is slightly ......MORE |
Vitamin D supplements benefit bone metabolism of younger patients taking tenofovirMichael Carter | 12 years ago Vitamin D supplementation is associated with an improvement in a key marker of bone health in HIV-p......MORE |
Smoking cessation counselling and treatment during routine HIV care helps patients to quitMichael Carter | 12 years ago The provision of smoking cessation counselling and therapy during routine HIV care increases the ch......MORE |
English public health indicators to include late HIV diagnosisRoger Pebody | 12 years ago The Department of Health this week announced the 66 ‘indicators’ with which the performance of ......MORE |
Studies from US and Spain show that hepatitis vaccination programmes not reaching target populationsMichael Carter | 12 years ago The majority of US adults at risk of hepatitis B remain unvaccinated against this potentially life-......MORE |
Can speeding up nevirapine clearance reduce the risk of resistance after PMTCT use?Carole Leach-Lemens | 12 years ago In a bid to reduce the risk of nevirapine resistance after the use of single-dose nevirapine to pre......MORE |
Common side-effects of hepatitis C protease inhibitors: clinical management advice publishedMichael Carter | 12 years ago The addition of the protease inhibitors telaprevir or boceprevir to hepatitis C treatment regimens ......MORE |
Vigilance over early weight loss on HIV treatment needed, Tanzanian study showsCarole Leach-Lemens | 12 years ago Nearly one-third of patients experienced substantial weight loss in the first ten months after star......MORE |
Smoking, not immunodeficiency or lung disease, increases lung cancer risk for patients with HIVMichael Carter | 12 years ago Cigarette smoking is the single most important risk factor for lung cancer in patients with HIV, Sw......MORE |
Upsurge in HIV diagnoses among IDUs in Greece and Romania - are reduced prevention services the cause?Michael Carter | 12 years ago New diagnosis and prevalence of HIV increased sharply among injecting drug users in Greece and Roma......MORE |
Is a viral load just below 50 copies/ml low enough to ensure the long-term success of HIV therapy?Michael Carter | 12 years ago Suppressing viral load to below 50 copies/ml may not be enough to ensure the long-term success of a......MORE |
HIV treatment integrated into general health care delivers 'equal or better' results in MSF programmesCarole Leach-Lemens | 12 years ago Outcomes for people taking antiretroviral treatment in Médecins sans Frontières’ (MSF) integrat......MORE |
Big increase in repeat pregnancy rates in HIV-positive women in UK and IrelandMichael Carter | 12 years ago Rates of repeat pregnancies among HIV-positive women in the UK and Ireland have increased substanti......MORE |
Zimbabwe: what will it take to achieve virtual elimination of infant HIV infections?Carole Leach-Lemens | 12 years ago Efforts to achieve "virtual elimination" of new HIV infections in infants by 2015 could prove highl......MORE |
Home-based counselling and testing identifies people in need of treatment earlierCarole Leach-Lemens | 12 years ago Home-based HIV counselling and testing (HBCT) was shown to be the most effective gateway for gettin......MORE |
Limited evidence that vitamin D supplements of any benefit for patients with HIVMichael Carter | 12 years ago There is only scant evidence that vitamin D supplementation is of benefit for patients with HIV, ac......MORE |
Guidelines published on management of interactions between anti-epileptic and anti-HIV drugsMichael Carter | 12 years ago Doses adjustments are required when certain antiretrovirals and anti-epileptic drugs are taken toge......MORE |
Vaccine provides strong protection against HIV-like infection in monkeysKeith Alcorn | 12 years ago A new vaccine approach provided monkeys with a high level of protection against a virulent form of ......MORE |
Rapid ‘combination’ test fails to detect many cases of acute HIV infectionRoger Pebody | 12 years ago A rapid, point-of-care test, which aims to reduce the ‘window period’ through the detection of ......MORE |
Task shifting for male medical circumcision safe: international reviewCarole Leach-Lemens | 12 years ago With proper training and supervision task shifting of medical male circumcision to non-physician cl......MORE |
Antiviral treatment doesn't prevent short episodes of genital herpes reactivationMichael Carter | 12 years ago High-dose antiviral treatment does not prevent short, sub-clinical shedding of the genital herpes v......MORE |
Europeans find high prevalence of lipodystrophy in HIV-positive childrenMichael Carter | 12 years ago A European study published in the online edition of the Journal of Acquired Immune Deficiency Syndr......MORE |
US approval for paediatric use of raltegravir, new chewable tablet also gets the go-aheadMichael Carter | 12 years ago Drug regulatory authorities in the US have approved raltegravir (Isentress) for the treatment of HI......MORE |
ART improves impact of therapeutic feeding in malnourished infants with HIVCarole Leach-Lemens | 12 years ago HIV-infected malnourished children in urban Malawi who got ART within three weeks of therapeutic fe......MORE |
Study identifies issues affecting the quality of life of patients living with HIVMichael Carter | 12 years ago Fears about transmitting HIV to others, worries about the future, self-esteem problems, difficulty ......MORE |
Similar HIV treatment outcomes among UK gay men across ethnic groupsMichael Carter | 12 years ago HIV treatment outcomes among gay men in the UK are similar across ethnic groups, investigators repo......MORE |
Early guidance on use of hepatitis C protease inhibitors in HIV-co-infected patientsMichael Carter | 12 years ago Doctors in the US state of Maryland have issued preliminary guidance for the use of hepatitis C pro......MORE |
TB leads to poorer CD4 cell gains after starting HIV treatmentMichael Carter | 12 years ago Tuberculosis (TB) is associated with an impaired immune response to antiretroviral therapy, accordi......MORE |
Would early treatment for everyone be better? Study poses the questionGus Cairns | 12 years ago A US study has found that patients infected with HIV in the previous six months who were given 36 w......MORE |
PEP guidelines for the UK revised to take account of undetectable viral loadRoger Pebody | 12 years ago New UK guidelines for the use of post-exposure prophylaxis (PEP) following sexual exposure have bee......MORE |
Alcohol increases desire for sex without condoms: systematic reviewMichael Carter | 12 years ago Alcohol consumption has an impact on the intention of individuals to have unprotected sex, accordin......MORE |
Ongoing risk behaviour likely cause of high HIV incidence rate among gay men treated with PEPMichael Carter | 12 years ago HIV incidence is high among gay men who use post-exposure prophylaxis (PEP), investigators from Ams......MORE |
Gay men having unprotected sex think that having HIV is still a big deal, but that it’s now harder to transmitRoger Pebody | 12 years ago A study of Australian gay men examining unprotected sex and the beliefs that are associated with it......MORE |
Electrocautery ablation: safe and effective treatment of high-grade pre-cancerous anal lesions in gay menMichael Carter | 12 years ago A clinic-based intervention offers safe and effective treatment for high-grade pre-cancerous anal l......MORE |
Nevirapine and cotrimoxazole prophylaxis safe in HIV-exposed, uninfected infantsKeith Alcorn | 12 years ago Use of nevirapine with cotrimoxazole prophylaxis in HIV-exposed uninfected infants (HIV-EU) until s......MORE |
Nevirapine and cotrimoxazole prophylaxis safe in HIV-exposed, uninfected infantsCarole Leach-Lemens | 12 years ago Use of nevirapine with cotrimoxazole prophylaxis in HIV-exposed uninfected infants (HIV-EU) until s......MORE |
Adding rituximab to chemotherapy regimens improves outcomes for AIDS-related lymphomasMichael Carter | 12 years ago The addition of rituximab to chemotherapy regimens for the treatment of AIDS-related lymphomas impr......MORE |
HIV stigma divides and fragments gay communitiesRoger Pebody | 12 years ago A review of research studies has identified a growing division within gay communities, in which HIV......MORE |
Co-infection with hepatitis B worsens HIV-related outcomesMichael Carter | 12 years ago Co-infection with hepatitis B virus increases the risk of AIDS or death for patients newly diagnose......MORE |
Hepatitis B genotype B associated with poorer liver-related outcomes in Taiwanese patients co-infected with HIV and hepatitis BMichael Carter | 12 years ago Liver-related outcomes are poorer in HIV-positive patients who are co-infected with hepatitis B vir......MORE |
Earlier deaths in people with HIV due to drugs, alcohol, co-infections, poorly controlled HIV - not rapid ageingMichael Carter | 12 years ago Patients taking antiretroviral therapy have the same mortality risk as individuals in the general p......MORE |
Treatment switches after CD4 count decline reduce risk of death by 75% in Zambia, MalawiCarole Leach-Lemens | 12 years ago Mortality was reduced by about 75% among adults experiencing immunological failure according to the......MORE |
Hepatitis C doesn't affect cognitive function of women, but some evidence HIV doesMichael Carter | 12 years ago Infection with hepatitis C does not affect the cognitive performance of women with or at risk of HI......MORE |
Long-term use of HIV drugs is safe, does not raise risk of death, study showsMichael Carter | 12 years ago A large international study has provided persuasive evidence of the long-term safety of antiretrovi......MORE |
Mild kidney problems in patients with HIV can identify patients with hardening of the arteriesMichael Carter | 12 years ago Emergent kidney dysfunction is associated with an increased risk of hardening of the arteries in pa......MORE |
Cardiovascular risks reduced for patients with HIV by therapy with metformin and changes to diet and exerciseMichael Carter | 12 years ago Treatment with the anti-diabetes drug metformin helps prevent the progression of sub-clinical cardi......MORE |
High rate of new diagnoses when gay men phoned and asked to come back for sexual health check-upRoger Pebody | 12 years ago It’s feasible for sexual health clinics to take steps to invite ‘high-risk’ patients to come ......MORE |
Obama: US aims to provide HIV drugs for extra 2 million by end of 2013Keith Alcorn | 12 years ago The United States will aim to provide antiretroviral treatment for 6 million people around the worl......MORE |
UK considering lifting restrictions on health workers with HIV – as long as viral load is undetectableRoger Pebody | 12 years ago The Department of Health has opened a consultation on possible changes to its policy on the employm......MORE |
Undiagnosed infections and poor retention in care mean that few US patients fully benefit from HIV treatmentMichael Carter | 12 years ago Only a small minority of HIV-positive patients in the United States are gaining the full benefit of......MORE |
New vaccine against pneumococcal disease approved for UKKeith Alcorn | 12 years ago A new vaccine that may be more suitable for preventing pneumococcal disease in people living with......MORE |
3000 UK gay men diagnosed with HIV in 2010 – the highest number ever reportedRoger Pebody | 12 years ago Against a background of fewer diagnoses among heterosexuals infected abroad, the number of gay men ......MORE |
LGV cases almost triple in one year; UK public health officials warn against serosortingRoger Pebody | 12 years ago The number of gay men infected with the sexually transmitted infection lymphogranuloma venereum (LG......MORE |
Raltegravir kinder to bones and body fat than boosted protease inhibitors in Spanish trialMichael Carter | 12 years ago Raltegravir (Isentress)-based treatment appears to have a more favourable impact on fat accumulatio......MORE |
Patients on HIV therapy have an increased risk of stress and fragility fractures; no link to specific drugMichael Carter | 12 years ago Patients taking antiretroviral therapy have an increased risk of fractures typically associated wit......MORE |
Microbicide gel fails to work in large international trialGus Cairns | 12 years ago HIV prevention researchers and campaigners reacted with disappointment today when a trial of a teno......MORE |
Serodiscordant relationships for Africans in the UK often marked by uncertainty and disempowermentRoger Pebody | 12 years ago African people in the UK who are involved in a relationship where one person has HIV and the other ......MORE |
HIV prevalence in gay men is catching up in eastern Europe, survey findsGus Cairns | 12 years ago The EMIS survey of nearly 180,000 gay men in Europe has found that, while HIV prevalence in the ric......MORE |
Older anti-HIV drugs associated with increased risk of diabetesMichael Carter | 12 years ago New cases of diabetes in patients taking HIV therapy in France peaked between 1999 and 2000 but hav......MORE |
Mental health problems associated with worse clinical outcomes in HIV-positive US veteransMichael Carter | 12 years ago Over two-thirds of HIV-positive military veterans in the US have a mental health disorder, accordin......MORE |
HIV-positive caregivers in the US often feed infants pre-chewed food, a possible mode of HIV transmissionMichael Carter | 12 years ago Premastication of food for infants is a common practice among HIV-infected caregivers, US investiga......MORE |
Virulence of HIV has increased since first reports of AIDSMichael Carter | 12 years ago HIV may have evolved to become more virulent over the course of the epidemic, according to the resu......MORE |
Social vulnerability associated with lack of satisfaction with health care; doctors need to provide more supportRoger Pebody | 12 years ago Patients who are socially disadvantaged or who lack social support tend to be less satisfied with t......MORE |
Model shows excellent prognosis for UK gay men with HIVMichael Carter | 12 years ago New UK research provides further evidence of the dramatic impact of antiretroviral therapy on the p......MORE |
Among European gay men, rates of unsafe sex rise the further east you goRoger Pebody | 12 years ago The largest ever study of the sexual behaviour of men who have sex with men, which recruited 174,......MORE |
Ageing with HIV: attitudes and experiences of gay men shaped by length of diagnosisMichael Carter | 12 years ago 6c2e4fb1_f437_45a6_86ef_4c2af1f77d59_634570343940000000; expected86Invalid expression term ':'86; ex......MORE |
MSM living in hostile social environments more likely to have negative feelings about sexuality, less likely to test for HIVRoger Pebody | 12 years ago 6c2e4fb1_f437_45a6_86ef_4c2af1f77d59_634570343940000000; expected86Invalid expression term ':'86; ex......MORE |
Ritonavir dose of 50 mg could be sufficient to boost some protease inhibitors, trials neededMichael Carter | 12 years ago 6c2e4fb1_f437_45a6_86ef_4c2af1f77d59_634570343940000000; expected86Invalid expression term ':'86; ex......MORE |
Immunisation doesn't prevent mother-to-child HIV transmissions, but approach should not be abandoned, says expertMichael Carter | 12 years ago 6c2e4fb1_f437_45a6_86ef_4c2af1f77d59_634570343940000000; expected86Invalid expression term ':'86; ex......MORE |
Product information for raltegravir updated to warn of Stevens Johnson syndrome and hypersensitivity reactionMichael Carter | 12 years ago Product information for the HIV integrase inhibitor raltegravir (Isentress) has been updated in the......MORE |
US embraces treatment as prevention policy to achieve global 'AIDS-free generation'Keith Alcorn | 12 years ago The United States is now committed to a policy of creating the first AIDS-free generation by using ......MORE |
Drug combinations pairing AZT and efavirenz have highest resistance riskMichael Carter | 12 years ago HIV treatment regimens that include both efavirenz and AZT have the highest rates of resistance, ac......MORE |
Low HIV viral load doesn't cause inflammation or increase the risk of deathMichael Carter | 12 years ago Low level viral load does not increase inflammation or the risk of death, US investigators report i......MORE |
Poor adherence not enough to cause development of MDR-TBMichael Carter | 12 years ago Poor adherence may not be enough to cause multidrug-resistant tuberculosis, a laboratory study publ......MORE |
Screening and treatment removes TB as additional punishment in prisonsLesley Odendal | 12 years ago Innovative tuberculosis control programmes in prisons have reduced the prevalence of TB, and succes......MORE |
Funding for TB research and development decliningLesley Odendal | 12 years ago Funding levels for tuberculosis (TB) research and development (R &D) fell by 0.3% in 2010 compared ......MORE |
Rates of pneumococcal disease remain high in patients with HIVMichael Carter | 12 years ago Overall incidence of invasive pneumococcal disease is approximately 20 times higher in patients wit......MORE |
Hepatitis C transmission via injecting drug use: look beyond needles and syringesMichael Carter | 12 years ago Important insights into the continued spread of hepatitis C among injecting drug users are provided......MORE |
Persistence of very low levels of virus increase risk of relapse after hepatitis C therapyMichael Carter | 12 years ago The persistence of a low viral load during the first twelve weeks of hepatitis C therapy is associa......MORE |
Anal HPV infection more likely to persist in gay men compared to heterosexual menMichael Carter | 12 years ago An international team of investigators have found a possible explanation for the higher rates of an......MORE |
High level of acceptability of PrEP among UK gay men; daily dosing preferredRoger Pebody | 12 years ago While few gay men in England are currently aware of pre-exposure prophylaxis (PrEP), most men who a......MORE |
An intensive household counselling intervention reduces the burden of TB in ZAMSTAR studyTheo Smart | 12 years ago An intensive ‘household counselling’ intervention (involving TB contact tracing, multiple home ......MORE |
Indonesia: Injecting drug use a major risk factor for HIV-associated TBLesley Odendal | 12 years ago A study in Indonesia has found that people with HIV who injected drugs were 85% more likely to have......MORE |
Influential community figures can increase HIV testing by couplesCarole Leach-Lemens | 12 years ago Invitations given by influential people, supported by leaders of respected networks in the communit......MORE |
Testosterone therapy increases risk of red blood cell disorder for men with HIVMichael Carter | 12 years ago Testosterone replacement therapy is associated with an increased risk of over-production of red blo......MORE |
Wide variations between US states in HIV mortality ratesMichael Carter | 12 years ago There are large differences in HIV-related mortality rates between individual US states, according ......MORE |
Diabetes, high blood pressure increase risk of unemployment for people with HIVMichael Carter | 12 years ago Large numbers of patients are leaving employment in the years following their diagnosis with HIV, F......MORE |
Contraceptive injections and HIV transmission risk - what happens now?Roger Pebody | 12 years ago With new data suggesting that injectable contraceptives may double the risk both of acquiring and p......MORE |
HIV associated with an increased risk of cataract surgeryMichael Carter | 12 years ago HIV-positive patients are signficantly more likely to undergo surgery to remove cataracts in the ey......MORE |
Swiss show that concerns about potency of HIV therapy in context of non-subtype B infections are unfoundedMichael Carter | 12 years ago Patients infected with non-B HIV subtypes have virological outcomes which are at least as good – ......MORE |
'High viral load' should mean over half a million copies, not over 100,000, Rome study suggestsGus Cairns | 12 years ago A study by the University of Rome has found that a substantial proportion of patients with HIV are ......MORE |
Hepatitis C drug boceprevir achieves 70% viral suppression rate in HIV co-infected people within 24 weeksGus Cairns | 12 years ago Interim results presented at the Infectious Diseases Society of America (IDSA) conference yesterday......MORE |
Lung cancer is biggest killer in study of non-AIDS-defining cancersGus Cairns | 12 years ago A large cohort study of non-AIDS-defining cancers in people with HIV has found that while lung canc......MORE |
Diseases of ageing occurring 10 to 15 years earlier in patients with HIVMichael Carter | 12 years ago The diseases of ageing develop earlier in patients with HIV than in the general population, Italian......MORE |
Burden of non-AIDS-related illness increases as patients with HIV ageMichael Carter | 12 years ago Swiss research shows that non-AIDS-related diseases are now a major cause of illness in patients wi......MORE |
New European HIV treatment guidelines expand treatment recommendations but anticipate possible drug shortagesGus Cairns | 12 years ago The new edition of the European AIDS Clinical Society (EACS) treatment guidelines for people with H......MORE |
Fish pedicures unlikely to cause HIV infectionRoger Pebody | 12 years ago The Daily Mail and the Sun are alarming their readers today with articles alleging that “fish foo......MORE |
US panel updates antiretroviral treatment guidelinesLiz Highleyman | 12 years ago On October 14th the US Department of Health and Human Services (DHHS) issued updated guidelines for......MORE |
Switching from efavirenz to rilpivirine single tablet is safe and effectiveLiz Highleyman | 12 years ago People with undetectable viral load who switched from the efavirenz-containing Atripla single table......MORE |
People on methadone can succeed on hepatitis C treatmentLiz Highleyman | 12 years ago Opiate users on methadone maintenance therapy can be successfully treated for chronic hepatitis C a......MORE |
Patients with both HIV and diabetes have an increased risk of albuminuriaMichael Carter | 12 years ago HIV-positive individuals with diabetes have a significantly higher prevalence of albuminuria than p......MORE |
Gene variant that helps hepatitis C treatment may hinder HIV treatmentGus Cairns | 12 years ago A common variant in a gene that doubles the chance of hepatitis C treatment working in people coin......MORE |
Testing people with conditions suggesting HIV could pick up more recent infections, Europe-wide study findsGus Cairns | 12 years ago A pilot study in in 14 European countries, in which groups of patients presenting with one of eight......MORE |
Raltegravir continues to perform well at four yearsKeith Alcorn | 12 years ago People taking the HIV integrase inhibitor raltegravir (Isentress) continued to show good viral supp......MORE |
Raltegravir continues to performs well at four yearsKeith Alcorn | 12 years ago People taking the HIV integrase inhibitor raltegravir (Isentress) continued to show good viral supp......MORE |
Raltegravir continues to perform well at four yearsLiz Highleyman | 12 years ago People taking the HIV integrase inhibitor raltegravir (Isentress) continued to show good viral supp......MORE |
Dolutegravir is potent but twice-daily works betterLiz Highleyman | 12 years ago The novel integrase inhibitor dolutegravir is among the most potent antiretroviral agents studied t......MORE |
How common is neurocognitive impairment in people with HIV? It depends who you compare them withGus Cairns | 12 years ago How much more common is brain impairment and dementia in people with HIV than in the general popul......MORE |
HIV and TB activist Winstone Zulu deadKeith Alcorn | 12 years ago The prominent HIV and TB activist Winstone Zulu has died at the age of 47 in hospital in Lusaka. M......MORE |
UK: Life expectancy on HIV treatment improving, shows importance of prompt diagnosis and treatmentMichael Carter | 12 years ago The life expectancy of patients receiving antiretroviral therapy in the UK improved significantly b......MORE |
Reduced susceptibility to first-line drug causes change in UK gonorrhoea prescribing practiceMichael Carter | 12 years ago UK Prescribing guidance for the treatment of gonorrhoea needs to change because of increasing preva......MORE |
Overweight patients have best gains in CD4 cell count twelve months after starting HIV therapyMichael Carter | 12 years ago Patients who would normally be classified as overweight have the biggest increases in their CD4 cel......MORE |
Detectable viral load in patients taking HIV therapy associated with poor control of other chronic health problemsMichael Carter | 12 years ago Poor control of HIV is associated with sup-optimal management of other serious health condition, US......MORE |
Waist circumference and triglycerides: simple measures of increased cardiovascular risk for patients with HIVMichael Carter | 12 years ago Measuring waist circumference and triglyceride levels may be an easy way of identifying which HIV-p......MORE |
Global survey shows high frequency of resistance after first-line ART failure in childrenCarole Leach-Lemens | 12 years ago 90% of HIV-infected children in the resource-poor regions of Africa, Asia and Latin America had at ......MORE |
Efavirenz may be under-dosed in childrenCarole Leach-Lemens | 12 years ago In a cohort of three to 12 year-old HIV-infected Ugandan children taking once-daily efavirenz accor......MORE |
Non-surgical device provides safe and effective circumcision without need for anaesthetic or stitchesMichael Carter | 12 years ago A device that provides non-surgical male circumcision without anaesthetic or the need for stitches ......MORE |
Uncontrolled viral load increases risk of AIDS for patients with a CD4 cell count above 350Michael Carter | 12 years ago Uncontrolled HIV replication is associated with an increased risk of AIDS for patients with a CD4 c......MORE |
Expert panel picks `best buys` for HIV preventionKeith Alcorn | 12 years ago If $10 billion of new money can be spent on HIV prevention over the next five years, the priorities......MORE |
Expert panel picks 'best buys' for HIV preventionKeith Alcorn | 12 years ago If $10 billion of new money can be spent on HIV prevention over the next five years, the priorities......MORE |
Tenofovir PrEP arm dropped in women's HIV prevention trialKeith Alcorn | 12 years ago A major HIV prevention trial comparing a tenofovir microbicide with two forms of oral pre-exposure ......MORE |
Point-of-care CD4 test improves retention and treatment initiation in MozambiqueKeith Alcorn | 12 years ago The use of a point-of-care CD4 cell count test dramatically reduced the rate of loss to follow-up a......MORE |
Haiti: Early HIV treatment cost-effective in one of the world's poorest countriesCarole Leach-Lemens | 12 years ago Starting HIV treatment early, when CD4 cell counts fell below 350 cells/mm3 in accordance with curr......MORE |
Missed appointments in early years of HIV care associated with longer time to HIV suppression and higher cumulative viral loadMichael Carter | 12 years ago Patients who miss clinic appointments in the two years after they enter HIV care take longer to sup......MORE |
Older age and immune response to CMV affect CD4 cell recovery after starting HIV therapyMichael Carter | 12 years ago Older age and a strong immune response to CMV infection adversely affect CD4 cell count recovery in......MORE |
HIV treatment at 500 CD4 level would put half of patients in need of ART within a year of seroconversionMichael Carter | 12 years ago Raising the CD4 cell threshold for the initiation of antiretroviral therapy to 500 cells/mm3 would ......MORE |
Beliefs about efficacy of HIV treatment predict which urban poor patients start antiretroviral therapyMichael Carter | 12 years ago Poor patients are more likely to start HIV therapy if they believe that treatment will benefit thei......MORE |
Crushing Kaletra tablets for kids leads to lower drug levelsCarole Leach-Lemens | 12 years ago Using crushed lopinavir/ritonavir (Kaletra) tablets in children with HIV because of difficulties in......MORE |
Mobile testing units show success in linking people to HIV care, treatmentCarole Leach-Lemens | 12 years ago Linkage to facility-based HIV care from a mobile testing unit is feasible, South African researcher......MORE |
Couples often disagree on what they’ve told each other, study findsGus Cairns | 12 years ago A US study on heterosexual couples at high risk of HIV finds that individuals’ interpretation of ......MORE |
One in five refused ART in Soweto, even when in needCarole Leach-Lemens | 12 years ago One in five newly diagnosed ART eligible adults attending the Zazi Testing Center, Perinatal HIV Re......MORE |
One in five refusing ART in Soweto, even when in needCarole Leach-Lemens | 12 years ago One in five newly diagnosed ART eligible adults attending the Zazi Testing Center, Perinatal HIV Re......MORE |
Study from Zambia highlights importance of comprehension and consent in male circumcision programmesGus Cairns | 12 years ago A study from Zambia has found that the majority of adolescent boys attending male circumcision pro......MORE |
Media campaign on disclosure and stigma changes gay men’s attitudesRoger Pebody | 12 years ago A Canadian campaign which asked gay men “If you were rejected every time you disclosed, would you......MORE |
Gene therapy for HIV is “progress towards functional cure” say researchersKeith Alcorn | 12 years ago Investigators of a new gene therapy approach to HIV treatment claim that their findings represent ......MORE |
Disappointing results from two peer education projects in southern AfricaRoger Pebody | 12 years ago Two large HIV prevention programmes that recruited people to educate their friends and classmates h......MORE |
New anti-hepatitis C drug BMS-790052 does well in Phase IIa studyMichael Carter | 12 years ago Up to 83% of individuals with chronic hepatitis C virus achieved a sustained virological response a......MORE |
Switching to once-daily etravirine a safe and effective option for individuals taking suppressive protease inhibitor therapyMichael Carter | 12 years ago Patients taking a virologically suppressive HIV treatment combination can safely switch from a prot......MORE |
A fifth of patients discontinue Atripla within a year, CNS side-effects the main reasonMichael Carter | 12 years ago A fifth of patients who start antiretroviral therapy with Atripla switch to an alternative regimen ......MORE |
Big falls in prevalence of protease inhibitor and triple-class resistanceMichael Carter | 12 years ago The prevalence of HIV resistance to protease inhibitors fell sharply between 2003 and 2010, accordi......MORE |
The safety spectrum: gay men use many ways to moderate their sexual riskGus Cairns | 12 years ago The vast majority of gay men, HIV-positive and negative, make some effort to moderate their risk of......MORE |
Motivational interviewing, widely used counselling technique, may not work well for sexual behaviour changeGus Cairns | 12 years ago A meta-analysis of sexual risk behaviour reduction using the counselling technique known as motivat......MORE |
The spirit is willing, but... sex in the HIV-positive over-50sGus Cairns | 12 years ago Although the average age of the HIV-positive population is increasing, in both richer and poorer co......MORE |
'Less education' associated with PrEP and PEP use: only one in five gay men yet aware of PrEPGus Cairns | 12 years ago A survey (Mansergh) of 454 HIV-negative gay men in four US cities (New York, Los Angeles, Chicago ......MORE |
Viral load increasingly features in safer-sex discussion and decisions by HIV-positive gay men and their partnersGus Cairns | 12 years ago A Dutch study presented at the Tenth AIDS Impact conference this week showed that HIV-positive gay......MORE |
Brief incarceration increases risk of rebound in viral load for patients taking HIV therapyMichael Carter | 12 years ago Brief incarceration is associated with an increased risk of virological failure for injecting drug ......MORE |
Over half of pregnant UK women with HIV present late for antenatal careGus Cairns | 12 years ago Women in the UK who have HIV (previously diagnosed or not) are more than twice as likely to present......MORE |
Coffee consumption reduces side-effects in people on hepatitis C treatmentGus Cairns | 12 years ago Drinking three or more cups of coffee a day reduced the incidence of self-reported side effects by......MORE |
Both HIV replication and some types of antiretroviral therapy contribute to cardiovascular riskMichael Carter | 12 years ago US research published in the online edition of Clinical Infectious Diseases suggests that both unco......MORE |
First-line HIV treatment works just as well in routine care as in clinical trialsMichael Carter | 12 years ago First-line antiretroviral therapy is just as effective in routine clinical care as in randomised co......MORE |
Cumulative viral load: an important measure of risk of death in patients with HIVMichael Carter | 12 years ago Cumulative viral load - the total amount of viral replication measured over a long period - is asso......MORE |
South Africa: CD4 count at time of HIV diagnosis improves retention in care for patients who need ART immediatelyCarole Leach-Lemens | 12 years ago Patients attending an urban primary healthcare clinic in the inner city of Johannesburg who got a C......MORE |
Kenya: Despite free ARVs, delayed treatment often due to povertyCarole Leach-Lemens | 12 years ago Over a third of participants with an eligible CD4 cell count in a cohort of HIV serodiscordant coup......MORE |
Unexplained liver enzyme increases in patients with HIV could be due to hepatitis E virus: screening recommendedMichael Carter | 12 years ago Infection with hepatitis E virus should be considered as a possible cause of unexplained elevations......MORE |
Fluctuating symptoms have major impact on quality of life and fitness to work, survey findsGus Cairns | 12 years ago Common but non-specific symptoms of uncertain cause can dominate the day-to-day life of some peopl......MORE |
Once-daily etravirine does well in patients starting HIV therapyMichael Carter | 12 years ago First-line HIV therapy that includes a once-daily dose of the new NNRTI etravirine is just as likel......MORE |
Plasma and rectal viral load correlated in HIV-positive gay men: supports use of treatment as preventionMichael Carter | 12 years ago Viral load in the blood and rectal secretions of HIV-positive gay men are highly correlated, accord......MORE |
Co-infection with hepatitis delta increases risk of death for patients with HIV and chronic hepatitis BMichael Carter | 12 years ago Infection with hepatitis delta virus is associated with an increased risk of death for HIV-positive......MORE |
Older anti-epileptic drugs associated with failure of HIV treatmentMichael Carter | 12 years ago An interaction means that some older anti-epileptic drugs and antiretroviral therapy should not be ......MORE |
Consistent relationship between depression and poor adherence to HIV therapyMichael Carter | 12 years ago Depression has a significant impact on adherence to antiretroviral therapy, according to a meta-ana......MORE |
House of Lords says UK needs new national HIV prevention campaign, bigger push for testingKeith Alcorn | 12 years ago The United Kingdom government must give much greater priority to HIV prevention, and consider a new......MORE |
Performance of PMTCT in routine programme matches clinical trials, Botswana reportsCarole Leach-Lemens | 12 years ago Formula-fed infants born to women who started ART during pregnancy under routine programme conditio......MORE |
Only four US state AIDS Drug Assistance Programmes cover all recommended cardiovascular risk-reduction therapiesMichael Carter | 12 years ago The provision of medication to reduce the risk of cardiovascular disease by AIDS Drug Assistance Pr......MORE |
Abuse by partner may be common in HIV-positive gay menMichael Carter | 12 years ago The majority of a sample of HIV-positive gay men had recently been abused by a partner, US investig......MORE |
NRTI-sparing combination of darunavir/ritonavir and raltegravir not a good option for patients with high viral loadMichael Carter | 12 years ago An HIV treatment combination comprising ritonavir-boosted darunavir and raltegravir has “acceptab......MORE |
Unprotected sex eight times more common in serious relationships than casual ones, US gay youth study findsGus Cairns | 12 years ago The strongest single predictor of not using condoms in anal sex in a group of young US gay men was ......MORE |
Risk factors for development of TB after starting HIV therapy identified in North American researchMichael Carter | 12 years ago The development of tuberculosis (TB) after the initiation of antiretroviral therapy is associated w......MORE |
Study shows 'remarkable' effectiveness of modern HIV treatmentMichael Carter | 12 years ago US investigators have found evidence of the “remarkable” success of antiretroviral therapy in d......MORE |
Canadian study finds criminalisation confusion "chills" open and honest discussion of HIV risk-takingEdwin J. Bernard | 12 years ago The lack of clarity over when a person with HIV has a legal obligation to disclose their HIV-positi......MORE |
Over half of all new HIV diagnoses in Barcelona are lateMichael Carter | 12 years ago Over half of all new HIV diagnosis in the Spanish city of Barcelona are late, according to research......MORE |
Big increase in HIV and syphilis diagnoses in US among young black gay menMichael Carter | 12 years ago HIV and syphilis diagnoses among young gay and other men who have sex with men (MSM) increased in......MORE |
Some rapid hepatitis C tests have high false-negative rate in people with HIVMichael Carter | 12 years ago Approximately 9% of hepatitis C infections in HIV-positive individuals are missed by some rapid hep......MORE |
Further evidence that 'breast is best' for children of mothers with HIV in sub-Saharan AfricaCarole Leach-Lemens | 12 years ago Early weaning resulted in almost twice as many acute illnesses and hospitalisations among HIV-expos......MORE |
Further evidence that `breast is best` for children of mothers with HIV in sub-Saharan AfricaCarole Leach-Lemens | 12 years ago Early weaning resulted in almost twice as many acute illnesses and hospitalisations among HIV-expos......MORE |
Free cotrimoxazole improves retention in care among adults not yet eligible for ARTCarole Leach-Lemens | 12 years ago Providing free cotrimoxazole prophylaxis to adults not yet eligible for antiretroviral treatment in......MORE |
Cell-to-cell spread of HIV keeps viral reservoir going despite ARTKeith Alcorn | 12 years ago The presence of very low levels of HIV in the blood despite treatment with highly potent antiretrov......MORE |
Poor outcomes in 17 to 24 year olds using adult HIV servicesMichael Carter | 12 years ago American research published in the online edition of the Journal of Acquired Immune Deficiency Synd......MORE |
Pre-term delivery in mothers receiving HIV treatment: more research needed before changing guidelinesCarole Leach-Lemens | 12 years ago HIV-infected pregnant women on a protease-inhibitor (PI) triple antiretroviral regimen were twice a......MORE |
Treatment with statins reduces mortality risk for patients taking effective HIV therapyMichael Carter | 12 years ago Treatment with statins significantly reduces the risk of death for patients taking virologically su......MORE |
Higher mortality risk of publicly insured HIV patients in the US shows importance of screening for co-morbiditiesMichael Carter | 12 years ago Mortality rates are significantly higher among HIV-positive patients in the US whose care is paid f......MORE |
CMV infection may increase risk of mother-to-child HIV transmissionCarole Leach-Lemens | 12 years ago Cytomegalovirus infection during pregnancy or delivery may greatly increase the subsequent risk of ......MORE |
US approval for new three-drug combination pillKeith Alcorn | 12 years ago The US Food and Drug Administration has approved Complera, a combination pill containing three drug......MORE |
Ambulatory blood pressure monitoring shows that 15% of HIV patients had undiagnosed high blood pressureMichael Carter | 12 years ago Approximately 15% of HIV-positive patients had undiagnosed hypertension, Spanish investigators repo......MORE |
High levels of PrEP efficacy demanded by gay men before they consider it a replacement for condomsMichael Carter | 12 years ago PrEP would need to provide near perfect levels of protection against infection with HIV in order fo......MORE |
PrEP acceptable to gay men and few report that it would change their risk behaviourMichael Carter | 12 years ago Approximately 50% of gay men said they were likely to use pre-exposure prophylaxis (PrEP), but few ......MORE |
Cotrimoxazole in HIV-exposed but uninfected infants may undermine benefits of breastfeeding; trial needed, say paediatriciansCarole Leach-Lemens | 12 years ago Cotrimoxazole prophylaxis may not provide significant protection against bacterial infections in HI......MORE |
Variations in mitochondrial DNA affect CD4 gains in black patients taking successful HIV therapyMichael Carter | 12 years ago Variations in mitochondrial DNA are associated with poorer CD4 cell gains after the initiation of a......MORE |
Accelerated hardening of the arteries in patients with HIV; traditional risks the main causeMichael Carter | 12 years ago Atherosclerosis is accelerated in HIV-positive patients, according to research published in the onl......MORE |
Pregnancy doubled risk of female-to-male HIV transmission in Partners in Prevention studyCarole Leach-Lemens | 12 years ago Pregnancy increased the risks of female-to-male HIV transmission two-fold among over 3300 serodisco......MORE |
Steady HIV infection rate in the US conceals large increases in young gay and black menGus Cairns | 12 years ago About 50,000 adults a year are being infected with HIV in the US, a new estimate by the country’s......MORE |
Narrow window to avert HIV epidemics among MSM in Middle East and North AfricaMichael Carter | 12 years ago HIV epidemics are emerging among men who have sex with men (MSM) in a number of Middle Eastern and ......MORE |
Low but detectable viral load during HIV treatment involves a risk of resistanceMichael Carter | 12 years ago Drug resistance frequently develops in patients who have a persistent low detectable viral load whe......MORE |
Poor CD4 cell recovery after starting HIV treatment should be a cause for concern, close monitoring neededMichael Carter | 12 years ago Patients whose CD4 cell count does not recover despite achieving virologic control with HIV therapy......MORE |
Retention of pre-ART patients poor in sub-Saharan AfricaLesley Odendal | 12 years ago More than two-thirds of people who tested positive for HIV but weren't yet eligible for treatment w......MORE |
Boceprevir response and resistance differs according to HCV genotype 1 subtypeLiz Highleyman | 12 years ago People with hepatitis C virus (HCV) genotype 1b respond better to boceprevir and are less likely to......MORE |
Valaciclovir slows HIV disease progression in pregnant and breastfeeding womenCarole Leach-Lemens | 12 years ago Valaciclovir used to suppress herpes simplex virus 2 (HSV-2) in HIV co-infected pregnant and post-p......MORE |
Herpes drugs and viral load: valaciclovir works better than aciclovirGus Cairns | 12 years ago The anti-herpes drug valaciclovir (Valtrex, valacyclovir in the US) produced a 17-fold (1.23 log) r......MORE |
New integrase inhibitor dolutegravir looks potent and well-toleratedLiz Highleyman | 12 years ago The next-generation HIV integrase inhibitor dolutegravir (S/GSK1349572) suppressed HIV viral load a......MORE |
High levels of unmet need for family planning in people with HIV - couples unaware of conception and contraception optionsRoger Pebody | 12 years ago In Kenya, Tanzania and Namibia just 46% of HIV-positive women and 28% of HIV-positive men have disc......MORE |
What's next for HIV prevention? Paying people to be healthyRoger Pebody | 12 years ago Researchers are investigating the impact of offering financial incentives to people who are at risk......MORE |
Infant prophylaxis during breastfeeding reduces risk of HIV infection by 71%Carole Leach-Lemens | 12 years ago Extended use of nevirapine or zidovudine and nevirapine in infants can reduce the risks of HIV tran......MORE |
Another NRTI-sparing regimen does well in treatment-naive patientsMichael Carter | 12 years ago A nucleoside-sparing regimen based on raltegravir and ritonavir-boosted darunavir is as safe and ef......MORE |
Gay men’s PrEP study final results: near 90% efficacy in men who took drug, but adherence even lower than thoughtGus Cairns | 12 years ago A completed series of investigations into the iPrEx study of tenofovir/FTC(Truvada) at pre-exposure......MORE |
New NNRTI lersivirine matches efavirenz in phase 2 studyLiz Highleyman | 12 years ago Lersivirine, an investigational non-nucleoside reverse transcriptase inhibitor (NNRTI), lowered HIV......MORE |
HIV vaccine technologists edge nearer to effective designsGus Cairns | 12 years ago A vaccine symposium held at the sixth International AIDS Society conference in Rome heard how desig......MORE |
Hormonal contraceptive use increases women’s risk of acquiring and transmitting HIVRoger Pebody | 12 years ago A two-year, seven-country study has concluded that women using hormonal contraceptives, particularl......MORE |
Task shifting of HIV care to nurses: sucesses, but problems to watch out forTheo Smart | 12 years ago “A nurse-led service can deliver ART care as effectively as a doctor-driven one, and even improve......MORE |
Task-shifting of HIV care to nurses: sucesses, but problems to watch out forTheo Smart | 12 years ago “A nurse-led service can deliver ART care as effectively as a doctor-driven one, and even improve......MORE |
Once-daily elvitegravir matches raltegravirLiz Highleyman | 12 years ago The experimental HIV integrase inhibitor elvitegravir works as well as raltegravir (Isentress) for ......MORE |
HIV treatment in primary infection: 48 week course modestly delays CD4 dropKeith Alcorn | 12 years ago A 48-week course of antiretroviral treatment started within six months of becoming infected modestl......MORE |
The roll-out of male circumcision: reduction in HIV prevalence, condom use maintainedRoger Pebody | 12 years ago The ongoing roll-out of male circumcision in Orange Farm, South Africa has succeeded in bringing th......MORE |
Cognitive impairment still common but ART reduces riskLiz Highleyman | 12 years ago Cognitive impairment remains common amongst people with HIV and is linked to more severe immune def......MORE |
From 'what if' to 'what now': implementing the new prevention technologiesGus Cairns | 12 years ago Two consecutive sessions at the sixth International AIDS Society conference in Rome yesterday were ......MORE |
Maraviroc improves liver fibrosis in HIV/hepatitis C co-infected patientsMichael Carter | 12 years ago Treatment with maraviroc is associated with the regression of liver fibrosis in HIV-positive patien......MORE |
Treatment as prevention: what are the next steps?Keith Alcorn | 12 years ago Turning treatment into a prevention tool that can end the HIV pandemic will require not one, but a ......MORE |
Small study shows women on stable HIV therapy have very low levels of HIV and high drug concentrations in genital fluidsGus Cairns | 12 years ago A study of paired samples collected from the blood and cervico-vaginal fluid (CVF) of 20 women on s......MORE |
Raltegravir combined with Kaletra associated with good preservation of bone density over 96 weeksMichael Carter | 12 years ago A two-drug antiretroviral combination comprising raltegravir and ritonavir-boosted lopinavir has on......MORE |
South Africa’s PMTCT programme reduces mother-to-child transmission to under 4%Carole Leach-Lemens | 12 years ago Nine years after the start of a national prevention of mother-to-child transmission (PMTCT) program......MORE |
Viral suppression reduces HIV risk despite more sex and ‘condom fatigue’ in patients starting treatment in CameroonGus Cairns | 12 years ago Concerns that HIV treatment may lead to increased rates of unprotected sex and a decline in condom ......MORE |
Daily aciclovir slows HIV disease progression and reduces viral loadMichael Carter | 12 years ago Daily treatment with standard-dose aciclovir delays HIV disease progression and lowers viral load i......MORE |
Testing project using social networks in rural Tanzania effective in identifying people with undiagnosed infectionRoger Pebody | 12 years ago A pilot project in which people with HIV encouraged their friends and neighbours to be tested for H......MORE |
How best to deploy point-of-care CD4 cell testing in resource-limited settings?Theo Smart | 12 years ago Widespread introduction of point-of-care (POC) CD4 cell tests that don’t require a laboratory tec......MORE |
Pre-exposure prophylaxis does work for women, two studies findGus Cairns | 12 years ago Two studies of the use of oral pre-exposure prophylaxis (PrEP) in heterosexual people show that ora......MORE |
HPTN 052: early treatment reduces serious illness by 40%Keith Alcorn | 12 years ago Early treatment in the HPTN 052 study of treatment as prevention reduced serious illness by around ......MORE |
Treatment is prevention: HPTN 052 study shows 96% reduction in transmission when HIV-positive partner starts treatment earlyKeith Alcorn | 12 years ago Results from a trial showing that antiretroviral treatment prevents HIV from being passed onto unin......MORE |
Life expectancy for people with HIV in Africa may be comparable to general population if they are on treatmentCarole Leach-Lemens | 12 years ago Life expectancy for HIV-positive adults starting antiretroviral treatment (ART) in Uganda is compar......MORE |
Bacterial vaginosis raises women's risk of transmitting HIVRoger Pebody | 12 years ago A man who is in a relationship with an HIV-positive woman has a three times higher risk of acquirin......MORE |
Marker of cardiovascular disease also associated with bone problems in patients with HIVMichael Carter | 12 years ago An important marker of sub-clinical cardiovascular risk is associated with reduced bone mineral d......MORE |
Doubt remains if HIV therapy increases the risk of fragility fracturesMichael Carter | 12 years ago The relationship between HIV therapy and fracture risk is far from straightforward, US research pre......MORE |
The research agenda for antiretroviral prevention – now it gets complexRoger Pebody | 12 years ago We now know that starting antiretroviral therapy early, pre-exposure prophylaxis (PrEP) and vaginal......MORE |
Rome IAS conference is 'landmark moment' for HIV science, say expertsKeith Alcorn | 12 years ago The Sixth International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention opene......MORE |
Rome IAS conference is landmark moment for HIV science, say expertsKeith Alcorn | 12 years ago The Sixth International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention opene......MORE |
Antiretroviral prevention methods 'not in competition' with each otherKeith Alcorn | 12 years ago Antiretroviral prevention methods are not in competition, and policy makers and providers need to s......MORE |
Microbicide could be highly cost-effective in South African contextGus Cairns | 12 years ago A tenofovir-gel vaginal microbicide with the same efficacy as that seen in the CAPRISA 004 trial co......MORE |
Concurrent partnerships in men do not explain HIV incidence in women: number of partners doesGus Cairns | 12 years ago A study of HIV incidence amongst women in part of KwaZulu Natal in South Africa failed to find an......MORE |
Zambian study shows importance of early HIV test and fast ART for pregnant womenCarole Leach-Lemens | 12 years ago Starting ART at least 13 weeks before giving birth provides the greatest benefits in prevention of ......MORE |
Viral load monitoring of ART patients linked to lower death rate on treatment in southern AfricaCarole Leach-Lemens | 12 years ago After three years on ART patients enrolled in four scale-up programmes with routine viral load moni......MORE |
Two major studies show that HIV drugs prevent infectionKeith Alcorn | 12 years ago Two large studies of pre-exposure prophylaxis – use of antiretroviral drugs by uninfected people ......MORE |
Abacavir matches tenofovir in Canadian patients with high viral loadMichael Carter | 12 years ago The abacavir/3TC nucleoside combination is as potent as tenofovir/FTC, Canadian investigators repor......MORE |
Triple ART reduces maternal death, premature and still birth, Mozambique / Malawi study showsCarole Leach-Lemens | 12 years ago Women in Malawi and Mozambique on triple ART for three months or longer before giving birth were th......MORE |
Urgent need for guidance on management of heart disease risk in HIV-positive childrenMichael Carter | 12 years ago The majority of HIV-positive children who develop high cholesterol still have elevated cholesterol ......MORE |
Pre-existing immune deficiency main cause of AIDS-defining cancers in patients starting HIV therapyMichael Carter | 12 years ago New research has underlined the importance of the timely initiation of antiretroviral therapy. In a......MORE |
Couple-based counselling reduces HIV risk behaviour in drug-using couplesMichael Carter | 12 years ago Couple-based risk counselling reduces rates of unprotected sex in HIV-negative drug-using couples, ......MORE |
Confirmatory viral load reduces HIV treatment switches fourfold in 6-country African studyCarole Leach-Lemens | 12 years ago Targeted viral load testing to confirm treatment failure reduced unnecessary treatment regimen swit......MORE |
3TC has limited impact on HBV for hepatitis B / HIV-coinfected in South African trialKeith Alcorn | 12 years ago The inclusion of 3TC in antiretroviral therapy had few additional benefits for South African HIV-po......MORE |
Risk factors for HIV vary between African cities, need tailored responsesCarole Leach-Lemens | 12 years ago A comparative study in three large cities in southern Africa has found big differences in risk fact......MORE |
Mobile phone support helps patients with HIV stop smokingMichael Carter | 12 years ago A mobile phone counselling service can help people with HIV to stop smoking – at least in the sho......MORE |
People diagnosed with HIV who have never accessed medical care are often dissatisfied with post-test counsellingRoger Pebody | 12 years ago A qualitative study conducted with people who have tested HIV-positive but never had HIV medical ca......MORE |
Some older HIV drugs linked to premature ageingKeith Alcorn | 12 years ago Older antiretroviral drugs still widely used in low and middle-income countries accelerate a proces......MORE |
Can a blood test show if an HIV-positive patient has PCP?Michael Carter | 12 years ago A blood test may be able to show if an HIV-positive patient has the AIDS-defining opportunistic inf......MORE |
Kivexa and Truvada-based combinations associated with long-term gains in limb fat, not fat lossMichael Carter | 12 years ago Modern antiretroviral regimens based on Kivexa and Truvada are associated with long-term gains in l......MORE |
Only modest benefits from starting HIV therapy with a CD4 cell count above 500 compared to 350Michael Carter | 12 years ago Starting HIV therapy with a CD4 cell count above 500 cells/mm3 has only minimal additional benefits......MORE |
United States: opt-out HIV testing in clinical settings boosts HIV diagnoses among hard-to-reach groupsKeith Alcorn | 12 years ago Expanded HIV testing in the United States in clinical settings identified over 18,000 new HIV infec......MORE |
WHO issues global recommendations on services for men who have sex with men and transgender peopleKeith Alcorn | 12 years ago The World Health Organization has issued comprehensive recommendations on the prevention and treatm......MORE |
With special training, effective and safe hepatitis C therapy can be provided in primary careMichael Carter | 12 years ago Specially trained primary care providers can offer effective and safe treatment hepatitis C infecti......MORE |
Coffee drinking improves hepatitis C treatment response rate in mono-infected patientsMichael Carter | 12 years ago Coffee drinking is associated with improved responses to hepatitis C therapy, US investigators repo......MORE |
Coffee drinking improves hepatitis C treatment response rate in mon-infected patientsMichael Carter | 12 years ago Coffee drinking is associated with improved responses to hepatitis C therapy, US investigators repo......MORE |
Abacavir and cardiovascular risk: contradictory findings continue to emerge, mechanisms still unclearMichael Carter | 12 years ago Yet more studies looking at the potential cardiovascular risks associated with the use of the antir......MORE |
Invitation to test for HIV ups test rate among male partners of pregnant women in South AfricaCarole Leach-Lemens | 12 years ago Providing pregnant women with a written invitation to test for HIV for their male sexual partners s......MORE |
Heart attacks, non-AIDS cancers, more common in Botswana than US patients on HIV treatmentCarole Leach-Lemens | 12 years ago Incidence rates of non-AIDS-defining events (NADEs) in HIV-infected individuals on ART were fifty p......MORE |
Heart attacks, non-AIDS cancers, more common in Botswana than in US patients on HIV treatmentCarole Leach-Lemens | 12 years ago Incidence rates of non-AIDS-defining events (NADEs) in HIV-infected individuals on ART were 50% hig......MORE |
Intensive and targeted PEP counselling leads to less risky sex afterwards, fewer HIV infectionsRoger Pebody | 12 years ago People at higher risk of HIV infection who take post-exposure prophylaxis benefit from an intensive......MORE |
Tenofovir and bone loss: treatment causes early changes in thyroid hormone levelsMichael Carter | 12 years ago Treatment with tenofovir increases levels of a hormone associated with calcium metabolism, Spanish ......MORE |
Sexually transmitted infection rates in England drop for the first time in a decade - but continue to rise in gay menRoger Pebody | 12 years ago For the first time in a decade, there has been a small drop in the number of diagnoses of sexually ......MORE |
High prevalence of asymptomatic TB in HIV patients in Cape TownMichael Carter | 12 years ago HIV-positive patients in South Africa who are not yet taking antiretroviral therapy have a high pre......MORE |
Low CD4 cell count increases risk of non-AIDS-defining cancers for patients on HIV therapyMichael Carter | 12 years ago A CD4 cell count below 200 cells/mm3 is associated with an increased risk of infection-related non-......MORE |
Concerns about efficacy, cost and side-effects possible barriers to PrEP uptake in groups with high HIV riskMichael Carter | 12 years ago Concerns about cost, efficacy, and side-effects are possible barriers to the acceptability of pre-e......MORE |
HIV damages B-cells as well as T-cells: new treatment targets identifiedGus Cairns | 12 years ago The signature effect of HIV infection, and the cause of AIDS, is disruption of the T-lymphocyte bra......MORE |
Large gaps in the HIV prevention evidence baseRoger Pebody | 12 years ago An analysis of research that is relevant to HIV prevention in the United Kingdom has identified sev......MORE |
Tropism impacts on virological success of first-line HIV therapyMichael Carter | 12 years ago HIV tropism has a significant impact on the virological success of first-line antiretroviral therap......MORE |
HIV tests every 3 to 6 months suggested for all sexually active gay men in USMichael Carter | 12 years ago Sexually active gay and other men who have sex with men (MSM) should have an HIV test every three t......MORE |
HIV tests every 3 - 6 months suggested for all sexually active gay men in USMichael Carter | 12 years ago Sexually active gay and other men who have sex with men (MSM) should have an HIV every three to six......MORE |
Switch from efavirenz to raltegravir improves mood and lipid profilesMichael Carter | 12 years ago Switching from efavirenz (Sustiva) to raltegravir (Isentress) is associated with improvements in mo......MORE |
UNAIDS: Treat 15 million by 2015Keith Alcorn | 12 years ago Global funding for AIDS needs to increase by one-third in the short term and by 20% in the longer t......MORE |
HIV-positive patients who receive therapy for acute HCV can be cured with just 24 weeks of therapyMichael Carter | 12 years ago HIV-positive individuals with acute hepatitis C may be able to clear the infection with just 24 wee......MORE |
30 years of AIDS: remembering how it began - from those who were thereKeith Alcorn | 12 years ago Sunday June 5 sees the 30th anniversary of the first reports of the disease that later came to be k......MORE |
HIV-positive patients have good long-term responses to hepatitis A vaccinationMichael Carter | 12 years ago HIV-positive patients have a good response to vaccination against hepatitis A virus, US investigato......MORE |
Hair concentrations of atazanavir are associated with the success of HIV treatmentMichael Carter | 12 years ago Hair concentrations of the HIV protease inhibitor atazanavir (Reyataz) are strongly associated with......MORE |
UK government issues global HIV spending statementKeith Alcorn | 12 years ago The United Kingdom government has issued a new policy statement on global HIV spending, saying it......MORE |
Long-term CD4 cell gains on treatment weaker in over-50sMichael Carter | 12 years ago US investigators have found people with HIV aged 50 and over have weaker immune restoration after s......MORE |
First-line treatment for HIV-2: superior outcomes seen with a boosted protease inhibitorMichael Carter | 12 years ago An antiretroviral combination based on a boosted protease inhibitor should be “considered as firs......MORE |
Elevated CD8 cell count associated with HIV treatment failureMichael Carter | 12 years ago An elevated CD8 cell count is associated with an increased risk of HIV treatment failure for patien......MORE |
US research shows importance of healthy vitamin D levels for patients with HIVMichael Carter | 12 years ago New US research has shown that vitamin D levels are associated with a number of important outcomes ......MORE |
No superinfections among HIV-positive gay men in Amsterdam reporting risky sexMichael Carter | 12 years ago HIV superinfection appears to be extremely rare, a Dutch study published in the June 1st edition of......MORE |
Gene associated with increased risk of cirrhosis for HIV/HCV-co-infected patientsMichael Carter | 12 years ago A genetic mutation is associated with an increased risk of cirrhosis for patients co-infected with ......MORE |
US approval for hepatitis C drug telaprevirKeith Alcorn | 12 years ago The US Food and Drug Administration has approved a new hepatitis C drug telaprevir (Incivek), the a......MORE |
European approval recommended for hepatitis C drug boceprevirKeith Alcorn | 12 years ago The European Medicines Agency has recommended marketing approval for Merck’s hepatitis C protease......MORE |
Rilpivirine (Edurant) approved in United StatesKeith Alcorn | 12 years ago A new non-nucleoside reverse transcriptase inhibitor, rilpivirine, has been approved for first-line......MORE |
Novel vaccine did not protect monkeys against infection – but may have cured themGus Cairns | 12 years ago A novel vaccine using the common virus Cytomegalovirus (CMV) as the vector or container of proteins......MORE |
'Virtual Hospital' a satisfactory and safe way to deliver care to clinically stable HIV-positive patientsMichael Carter | 12 years ago A ‘Virtual Hospital’ that provides a comprehensive package of HIV care is a safe and feasible o......MORE |
Interruption of TB treatment due to drug supply problems common in UKKeith Alcorn | 12 years ago A quarter of United Kingdom hospitals providing TB treatment had to interrupt a course of treatment......MORE |
South African women with AIDS conspiracy beliefs half as likely to use condomsRoger Pebody | 12 years ago In Cape Town, African women who think that AIDS is man-made are half as likely as other African wom......MORE |
Further cuts in drug prices make tenofovir more affordable for low-income countriesKeith Alcorn | 12 years ago UNITAID, the international drug purchase fund, and the Clinton Health Access Initiative have announ......MORE |
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