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NHS England and local authorities must ensure routine availability of PrEP for HIV prevention by 1 April 2019, says coalition of charities
by NHIVNA Admin, 2018-07-17 09:00

HIV Nursing 2017
by NHIVNA Admin, 2017-06-17 10:55

National Standards of Peer Support in HIV launched
by NHIVNA Admin, 2017-06-15 10:05


Other latest news

Viral load in semen rapidly rebounds to infectious levels during HIV treatment breaks

Michael Carter | 1 day ago

Viral load rebounds rapidly in semen to potentially infectious levels following interruption o......MORE

PROUD qualitative findings: PrEP’s impact on sexual behaviour

Krishen Samuel | 2 days ago

Qualitative data from the PROUD study revealed that pre-exposure prophylaxis (PrEP) is an impo......MORE

Hepatitis C is detectable in rectal and nasal fluid

Keith Alcorn | 2 days ago

High levels of hepatitis C virus (HCV) can be found in the rectal and nasal fluids of people w......MORE

High prevalence and incidence of hypertension among South Africans starting ART

Michael Carter | 3 days ago

There is a high prevalence and incidence of hypertension (raised blood pressure) among HIV-pos......MORE

Recent incarceration increases HIV and hepatitis C risk for people who inject drugs

Michael Carter | 3 days ago

People who inject drugs (PWID) recently released from prison or jail have a substantially incr......MORE

Transgender women taking PrEP have lower levels of PrEP drugs, especially in rectal tissues, than cisgender men

Gus Cairns | 6 days ago

A study presented at last month’s HIV Research for Prevention conference (HIVR4P) in Madrid ......MORE

Early HIV treatment reduces the risk of liver fibrosis

Michael Carter | 7 days ago

Early antiretroviral therapy (ART) reduces the risk of liver fibrosis progression in people li......MORE

How has Glasgow responded to an outbreak of HIV among people who inject drugs?

Keith Alcorn | 8 days ago

...MORE

Fostemsavir, novel gp120 inhibitor, salvages nearly half of people with no other treatment options left

Gus Cairns | 8 days ago

The recent International Congress on Drug Therapy in HIV Infection (HIV Glasgow) featured tria......MORE

PrEP sorting: HIV-negative gay men prefer sexual partners who are using PrEP

Krishen Samuel | 8 days ago

PrEP status is a significant factor for HIV-negative men who have sex with men (MSM) when sele......MORE

Dolutegravir plus darunavir maintains viral suppression without NRTIs

Liz Highleyman | 9 days ago

A dual antiretroviral regimen containing dolutegravir (Tivicay) and boosted darunavir (Prezist......MORE

Gammora does not cure HIV

Roger Pebody | 9 days ago

An Israeli biotech company has issued a misleading press release which has encouraged some med......MORE

Reaching the men: who are the partners of the young women with HIV in South Africa?

Gus Cairns | 10 days ago

...MORE

Prolonged HIV suppression is possible using ibalizumab, analysis of highly drug-resistant people shows

Keith Alcorn | 13 days ago

A treatment regimen containing ibalizumab (Trogarzo), a monoclonal antibody designed to block ......MORE

How safe is PrEP? Meta-analysis finds no increased risk of serious side-effects

Gus Cairns | 13 days ago

A meta-analysis of randomised controlled trials of tenofovir or tenofovir/emtricitabine as pre......MORE

Hepatitis C increases the risk of premature delivery for pregnant women with HIV

Keith Alcorn | 13 days ago

Co-infection with hepatitis C greatly increases the risk of pre-term delivery for pregnant wom......MORE

Dolutegravir or lower-dose efavirenz equally effective, but less resistance with dolutegravir

Keith Alcorn | 14 days ago

Dolutegravir-based treatment was no more effective than treatment based on a 400mg dose of efa......MORE

Going local - prevention conference hears about rings, douches, and soluble suppositories

Gus Cairns | 15 days ago

...MORE

Beyond Truvada - what is the future of PrEP?

Roger Pebody | 15 days ago

...MORE

Bictegravir matches dolutegravir in first-line treatment

Keith Alcorn | 15 days ago

A triple combination containing the new integrase inhibitor bictegravir proved just as effecti......MORE

Neural tube defects and integrase inhibitors: studies show no further evidence of increased risk

Keith Alcorn | 16 days ago

No further evidence of an increased risk of infant neural tube defects related to the use of d......MORE

Two-drug protease inhibitor treatment as effective as three-drug treatment - and fewer stop due to side-effects

Keith Alcorn | 16 days ago

Antiretroviral treatment with a boosted protease inhibitor and one other drug is just as effec......MORE

Boston HIV clinic sees 90% reduction in infections in people being prescribed PrEP

Gus Cairns | 16 days ago

The Fenway clinic in Boston, Massachusetts, one of the first to institute a large pre-exposure......MORE

Substantial gaps in PrEP care continuum for trans women in San Francisco

Roger Pebody | 16 days ago

Only a third of trans women in San Francisco have talked to a healthcare provider about pre-ex......MORE

PrEP providers and communicators should stop talking about ‘risk’

Roger Pebody | 17 days ago

It’s unhelpful to frame the use of pre-exposure prophylaxis (PrEP) in terms of ‘risky beha......MORE

First large HIV prevention trial using antibodies will probably not be the last

Gus Cairns | 17 days ago

The HIV Research for Prevention conference (HIVR4P 2018) in Madrid last week was dominated by ......MORE

Generic PrEP bought online has correct amounts of emtricitabine and tenofovir

Michael Carter | 18 days ago

People buying generic PrEP (pre-exposure prophylaxis) online can be confident they are buying ......MORE

Vaginal rings, films, inserts or gels - it’s all about choice

Roger Pebody | 20 days ago

There is no single HIV prevention technology which suits everyone – young African women who ......MORE

The Miami monkey cured with two antibodies

Gus Cairns | 20 days ago

A ‘functional cure’ of HIV has been achieved in one monkey given gene therapy that induced......MORE

The long tail of injectable PrEP is especially long for women

Roger Pebody | 21 days ago

Around four in ten women and one in ten men taking injectable cabotegravir as pre-exposure pro......MORE

Far more people may be using PrEP than we know, HIV prevention conference hears

Gus Cairns | 22 days ago

Many more gay men and men who have sex with men (MSM) may be using pre-exposure prophylaxis (P......MORE

People with HIV can safely use immunotherapy for cancer

Liz Highleyman | 22 days ago

Treatment with an immune checkpoint inhibitor appears to be well tolerated and may work as wel......MORE

Viral suppression within three months of HIV diagnosis should be a policy target, NYC officials say

Michael Carter | 23 days ago

An undetectable viral load within three months of HIV diagnosis should be added as a target to......MORE

380,000 people on PrEP globally, mostly in the USA and Africa [updated]

Roger Pebody | 23 days ago

At least 381,580 people have started to take pre-exposure prophylaxis (PrEP) in 68 countries,......MORE

Drug resistance accumulates fast in people with low but detectable viral loads, Kenyan study finds

Gus Cairns | 24 days ago

A study measuring HIV drug resistance at two timepoints in Kenyan patients on second-line, pro......MORE

First HIV-positive to HIV-negative liver transplant raises intriguing questions for cure research

Keith Alcorn | 27 days ago

An HIV-negative child received a liver transplant from its HIV-positive mother and now appears......MORE

Majority of US young adults who use drugs are not tested for hepatitis C or HIV

Liz Highleyman | 27 days ago

Only about a third of adolescents and young adults diagnosed with opioid use disorder in the U......MORE

Integrated support intervention improves engagement with HIV and methadone treatment among people who inject drugs

Michael Carter | 28 days ago

Providing information on how to navigate care pathways, psychosocial support, and immediate an......MORE

Studies confirm long-term effectiveness of new single-tablet regimens

Liz Highleyman | 28 days ago

The newest once-daily, all-in-one HIV combination pills can maintain undetectable viral load f......MORE

Pain highly prevalent among people with HIV and has a major impact on mental health, quality of life, employment and use of healthcare

Michael Carter | 29 days ago

Pain is very common among people living with HIV (PLWH) and has a major impact on quality of l......MORE

Combined treatment for smoking cessation, anxiety and depression more effective than smoking cessation alone

Krishen Samuel | 29 days ago

A randomised control trial published in The Journal of Acquired Immune Deficiency Syndromes by......MORE

Internet-based intervention effective in the treatment of depression in people living with HIV

Alain Volny-Anne | 1 month ago

An online self-help intervention is effective in the treatment of mild to moderate depressive ......MORE

Wide range of views about switching to weekly, monthly or biannual ART

Michael Carter | 1 month ago

Two-thirds of people taking combination antiretroviral therapy (cART) would be interested in s......MORE

Anal HPV-16 infection significantly more common in men who have sex with men, especially those living with HIV

Keith Alcorn | 1 month ago

Anal infection with HPV-16, the type of human papillomavirus most strongly associated with ana......MORE

Older people less likely to be offered an HIV test in English sexual health clinics

Roger Pebody | 1 month ago

Despite their mandate to offer HIV testing to all attendees, sexual health clinics in England ......MORE

Efavirenz, but not dolutegravir, linked to neurological problems in children

Liz Highleyman | 1 month ago

Children born to HIV-positive women who take efavirenz (Sustiva or Stocrin, also a component o......MORE

TB vaccine halves risk of disease in people with latent TB

Keith Alcorn | 1 month ago

A vaccine against tuberculosis (TB) reduced the risk of developing active TB in HIV-negative p......MORE

Hepatitis C elimination in people living with HIV in the UK is feasible by 2021, British HIV Association says

Keith Alcorn | 1 month ago

Hepatitis C co-infection can be eliminated in people living with HIV in the United Kingdom by ......MORE

Another rare PrEP failure reported in San Francisco

Liz Highleyman | 1 month ago

A San Francisco man was apparently infected with partially resistant HIV despite consistent us......MORE

Dual-antibody combination therapy produces three to seven months of viral suppression without pills

Gus Cairns | 1 month ago

A group of researchers have for the first time used infusions of antibodies to produce prolong......MORE

Doravirine combination works well as a switch option

Liz Highleyman | 1 month ago

A combination pill containing doravirine (Delstrigo) maintains undetectable viral load in peop......MORE

Some gay and bisexual men see PrEP as a 'social problem'

Michael Carter | 1 month ago

Gay and bisexual men have differing attitudes towards men who are using pre-exposure prophylax......MORE

Adolescent girls’ male partners are not all much older, much wealthier ‘sugar daddies’

Roger Pebody | 1 month ago

The male partners of adolescent girls and young women in eSwatini (Swaziland) and South Africa......MORE

People living with HIV underestimate the harm of smoking

Keith Alcorn | 1 month ago

People with HIV in Denmark who smoke greatly underestimate the impact of smoking on life expec......MORE

Most PrEP users in Berlin obtained it from informal channels

Krishen Samuel | 1 month ago

Over half of men who have sex with men (MSM) living in Berlin who were using HIV pre-exposure ......MORE

Large proportion of people living with HIV, including gay men, would like to have children

Michael Carter | 1 month ago

Approximately 40% of HIV-positive adults starting antiretroviral therapy (ART) in the United S......MORE

One in five exposed to TB during HIV clinic visits, Malawi study finds

Keith Alcorn | 1 month ago

As many as one in five people attending an HIV clinic in Malawi had prolonged exposure to anot......MORE

Meta-analysis shows hepatitis C treatment is highly effective for drug users

Keith Alcorn | 1 month ago

Direct-acting antiviral treatment is highly effective at curing hepatitis C in people who inje......MORE

Study confirms STIs make no difference to undetectability and infectiousness in people taking HIV treatment

Gus Cairns | 1 month ago

A study conducted with gay men in Thailand has found that people who are diagnosed with HIV an......MORE

Lymph node biopsies in individuals with acute HIV infection are safe and well-tolerated

Alain Volny-Anne | 1 month ago

Biopsies of lymph nodes in the groin, performed in the context of acute HIV infection, are saf......MORE

Older age and baseline kidney function, not ARV choice, are key risk factors for chronic kidney disease in people with HIV in Australian cohort

Michael Carter | 1 month ago

Older age and lower baseline kidney function are the only significant risk factors for the dev......MORE

PEPFAR funded 15 million medical male circumcisions between 2007 and 2017

Gus Cairns | 1 month ago

PEPFAR (the US President’s Emergency Fund for AIDS Relief) has supported the voluntary medic......MORE

Loneliness associated with poorer cognitive function, mental health and physical health in older people with HIV

Michael Carter | 1 month ago

Loneliness in older HIV-positive adults is associated with reduced cognitive function as well ......MORE

Racial segregation associated with new HIV infections among black heterosexuals living in the US

Krishen Samuel | 1 month ago

A greater degree of racial segregation in urban areas of the United States is associated with ......MORE

Zoledronic acid is more effective than switching from tenofovir in HIV-positive people with low bone mineral density

Alain Volny-Anne | 1 month ago

Two infusions of zoledronic acid resulted in significantly greater increases in bone mineral d......MORE

"I approached him when he was in his good moods": how pregnant women introduce HIV self-tests to their partners

Keith Alcorn | 1 month ago

Providing HIV self-testing kits to pregnant women to encourage HIV testing in their male partn......MORE

Immunotherapy shows promise as a treatment for HIV-related Kaposi sarcoma

Michael Carter | 1 month ago

Immunotherapy may be an effective treatment for HIV-related Kaposi sarcoma (KS), according to ......MORE

US doctors’ organisation endorses event-based PrEP for the first time

Gus Cairns | 1 month ago

For the first time, a US-based professional HIV body has published guidelines endorsing event-......MORE

Do-it-yourself HIV prevention: who do men buying PrEP online get support from?

Roger Pebody | 1 month ago

Gay men in London who source their own supply of generic pre-exposure prophylaxis (PrEP) drugs......MORE

Findings of large study suggest that HIV should be considered a major risk factor for cardiovascular disease

Michael Carter | 1 month ago

People living with HIV are twice as likely to develop cardiovascular disease (CVD), according ......MORE

TB symptom screen less likely to detect active TB in people taking HIV treatment

Keith Alcorn | 2 month ago

The four-symptom screen for active tuberculosis (TB) that is recommended for all people livin......MORE

Stigma remains a substantial barrier in accessing HIV care in rural East Africa

Krishen Samuel | 2 month ago

A set of varied barriers adversely impact positive outcomes at different stages in the HIV car......MORE

High rates of smoking in people with HIV in sub-Saharan Africa

Michael Carter | 2 month ago

Having HIV is associated with a greater likelihood of cigarette smoking and using smokeless to......MORE

Two new doravirine pills approved in US

Liz Highleyman | 2 month ago

The US Food and Drug Administration (FDA) has approved two new products containing the next-ge......MORE

Developmental problems of children born to women with HIV linked to substance use and HIV, not antiretrovirals

Keith Alcorn | 2 month ago

Pre-term births and developmental problems in children born to mothers with HIV are associated......MORE

Starting from here - what PrEP programmes can learn from circumcision

Gus Cairns | 2 month ago

Funders, health providers and advocates should take lessons from the rollout of voluntary medi......MORE

What do older people living with HIV do to look after their own mental health?

Roger Pebody | 2 month ago

Older people living with HIV describe a range of strategies to maintain or improve their menta......MORE

Peer support is crucial for many people living with HIV

Roger Pebody | 2 month ago

Social support from peers living with HIV is of a different nature to the support received fro......MORE

Unstable housing associated with low CD4 cell count and detectable viral load for HIV-positive women in US

Michael Carter | 2 month ago

Unstable housing is associated with an increased risk of a detectable viral load and low CD4 c......MORE

Modest improvements in HIV knowledge and disclosure beliefs after summer camp for adolescents living with HIV in the UK

Roger Pebody | 2 month ago

An evaluation of the summer camp organised by the Children’s HIV Association (CHIVA) for 12-......MORE

Work to improve the HIV care continuum for black transgender women should concentrate on HIV diagnosis

Roger Pebody | 2 month ago

Less than half of black transgender women living with HIV in the United States are aware of th......MORE

Poorer ART outcomes show need to prioritise older people in HIV test and treat programmes

Michael Carter | 2 month ago

HIV testing and treatment programmes in sub-Saharan Africa need to prioritise older individual......MORE

HIV diagnoses in gay men in the UK decreased by a third in two years

Roger Pebody | 2 month ago

New HIV diagnoses in the UK have fallen again, with the greatest reduction seen in gay and bis......MORE

Indonesia: tackling HIV in one of the world’s fastest-growing epidemics

Gus Cairns | 2 month ago

A prospective study that recruited a significant proportion of people newly diagnosed with HIV......MORE

Some antiretroviral regimens associated with pre-term birth and low birth weight

Keith Alcorn | 2 month ago

Exposure to protease inhibitor (PI)-based regimens and non-nucleoside reverse transcriptase in......MORE

One in three women in US survey have negative attitudes towards PrEP

Gus Cairns | 2 month ago

A survey conducted by Planned Parenthood in the US state of Connecticut has found that althoug......MORE

Appropriate pain management may have role in key HIV treatment outcomes, suggests US research

Michael Carter | 2 month ago

Chronic pain was reported by a quarter of people living with HIV in an American study publishe......MORE

The work of a couple: how gay men in relationships come to trust that “Undetectable = Untransmittable”

Roger Pebody | 2 month ago

Having a relationship based on trust, commitment and familiarity helps Australian gay men rely......MORE

PrEP for female sex workers: non-judgemental attitudes and community involvement are keys to success

Gus Cairns | 2 month ago

Several studies presented at the 22nd International AIDS Conference (AIDS 2018) in Amsterda......MORE

Europe close to meeting UNAIDS 90-90-90 target but considerable variability between countries

Michael Carter | 2 month ago

The European region of the World Health Organization (WHO) is close to achieving the UNAIDS 90......MORE

Dolutegravir-based ART effective and safe for HIV-positive people taking standard TB treatment

Michael Carter | 2 month ago

Dolutegravir-based antiretroviral therapy (ART) is effective and safe when taken at the same t......MORE

Breastfeeding with undetectable viral load: genuine uncertainty on risk should be communicated to women with HIV, say Swiss doctors

Keith Alcorn | 2 month ago

Women with HIV on effective antiretroviral treatment in higher-income settings who have undet......MORE

Neuropsychiatric side-effects lead only 1 in 40 to drop dolutegravir, French study shows

Keith Alcorn | 2 month ago

A large French study of people taking HIV treatment that contained an integrase inhibitor foun......MORE

Giving gay men self-test kits increases testing by 50% - but STI tests decrease

Gus Cairns | 2 month ago

Gay men who were offered HIV home-testing kits took 50% more tests than men who only took HIV ......MORE

UK research shows that black patients of West African and Caribbean origin have higher rates of chronic kidney disease

Michael Carter | 2 month ago

The risk of chronic and end-stage kidney disease among HIV-positive people of African ethnicit......MORE

Starting treatment on the day of HIV diagnosis is acceptable and feasible for Thai patients

Keith Alcorn | 3 month ago

Starting treatment on the day of HIV diagnosis is acceptable and feasible for Thai patients, a......MORE

One in nine people may be able to control their viral load after stopping treatment, US study finds

Gus Cairns | 3 month ago

A US collaboration that pooled data from 14 scientific studies containing between them more th......MORE

People taking a protease inhibitor who have heart failure have an increased mortality risk, study claims

Michael Carter | 3 month ago

HIV-positive people who are taking antiretroviral therapy (ART) and are hospitalised due to he......MORE

HIV and chronic HCV co-infection prevalence in England highest among MSM

Michael Carter | 3 month ago

Men who have sex with men (MSM) make up the majority of people with chronic hepatitis C virus ......MORE

Treatment with modern antiretrovirals doesn't increase the risk of hypertension

Michael Carter | 3 month ago

There is no strong evidence that treatment with antiretrovirals significantly increases the ri......MORE

PrEP use taking off in Thailand and Vietnam

Gus Cairns | 3 month ago

Pre-exposure prophylaxis (PrEP) use is accelerating among men who have sex with men and transg......MORE

People with HIV receiving methadone and HIV drugs spend less time with detectable viral load

Keith Alcorn | 3 month ago

People on methadone maintenance treatment spent less time with a detectable viral load above 1......MORE

Studies show dolutegravir monotherapy is an unsafe switch option

Keith Alcorn | 3 month ago

Using dolutegravir alone, as maintenance treatment after achieving undetectable viral load on ......MORE

HIV infection is a risk factor for liver fat accumulation

Liz Highleyman | 3 month ago

People living with HIV are about twice as likely to develop steatosis, or fat accumulation in ......MORE

Diarrhoea continues to affect the quality of life of people with HIV in the modern treatment era

Roger Pebody | 3 month ago

A meta-analysis of 38 clinical trials of antiretroviral therapies (ART) conducted in the past ......MORE

PrEP spreads across Africa - slowly

Gus Cairns | 3 month ago

This year, 2018, will be the year that a really significant number of people in Africa started......MORE

Young adults with life-long HIV have a higher risk of cancer

Liz Highleyman | 3 month ago

Adolescents and young adults who acquired HIV before or at birth had a 13-fold higher likeliho......MORE

Increase in STIs in PrEP users is concentrated in a minority of men and is partly due to more STI screening

Roger Pebody | 3 month ago

There were significant increases in bacterial sexually transmitted infections (STIs) in gay an......MORE

Unintended pregnancies and desire for children: reproductive health needs of women living with HIV

Carole Leach-Lemens | 3 month ago

The needs for safe conception services and a wider choice of contraception for women living wi......MORE

Dolutegravir brings faster viral suppression in late pregnancy

Carole Leach-Lemens | 3 month ago

Among 60 women presenting to routine antenatal clinics in Kampala, Uganda and Cape Town, South......MORE

Most adolescent PrEP users in US are young women

Liz Highleyman | 3 month ago

Only 1.5% of people who have used pre-exposure prophylaxis (PrEP) in the United States are age......MORE

Reduced dose darunavir/ritonavir effective and safe for people switching while virally suppressed

Michael Carter | 3 month ago

A daily dose of the boosted protease inhibitor darunavir/ritonavir 400/100mg is at least as ef......MORE

Digital innovations are promoting HIV testing and prevention to MSM in Asia

Roger Pebody | 3 month ago

Innovative health promotion interventions engaging men who have sex with men (MSM) in south ea......MORE

Doravirine maintains higher rate of virological suppression over darunavir/ritonavir though 96 weeks of follow-up

Michael Carter | 3 month ago

The experimental non-nucleoside reverse transcriptase inhibitor (NNRTI) doravirine was more ef......MORE

Three-quarters of deaths of people with HIV in London are due to non-AIDS conditions

Roger Pebody | 3 month ago

Over three-quarters of deaths of people with HIV in London are due to non-AIDS conditions, wit......MORE

Supervised drug consumption sites offer opportunities for HCV testing and treatment

Liz Highleyman | 3 month ago

Most supervised drug consumption facilities offer hepatitis C virus (HCV) testing and referral......MORE

HIV linked to higher risk of heart failure

Liz Highleyman | 3 month ago

HIV infection is associated with a significantly increased risk of developing heart failure, b......MORE

Series of HIV outbreaks in people who inject drugs shows that ‘complacency is the new problem’

Roger Pebody | 3 month ago

There have been outbreaks of rapid HIV transmission among people who inject drugs in Athens, B......MORE

The kick that didn’t kill: first-ever randomised HIV cure study fails to eliminate infected cells

Gus Cairns | 3 month ago

One study whose results were eagerly awaited at the 22nd International AIDS Conference (AIDS 2......MORE

PrEP use linked to fewer new HIV infections in US states

Liz Highleyman | 3 month ago

As pre-exposure prophylaxis (PrEP) use continues to grow, epidemiological evidence is starting......MORE

Civil society under threat: How can HIV advocates resist the impact?

Lisa Power | 3 month ago

Civil society organisations (CSOs) providing HIV services and advocacy to key populations and ......MORE

HIV treatment services in African countries need to adapt to serve mobile and migrant populations

Roger Pebody | 3 month ago

Health facilities must be responsive to the needs of mobile individuals and of migrants if the......MORE

HIV elimination in gay men: what is working?

Lisa Power | 3 month ago

Substantial decreases in HIV diagnoses in key cities show the way to elimination of new HIV di......MORE

Kaposi's sarcoma remains a concern for people with HIV

Liz Highleyman | 3 month ago

A small proportion of people living with HIV continue to develop Kaposi's sarcoma (KS), a canc......MORE

Progress against HIV in young people lags behind as Africa's youth population grows

Keith Alcorn | 3 month ago

Africa is far off track in reducing new HIV infections among children and young people and is ......MORE

High uptake of HIV testing when self-tests are offered to outpatients in Malawi

Roger Pebody | 3 month ago

Most models of HIV self-test distribution are based on community settings, but providing self-......MORE

Test and treat studies show high rates of HIV diagnosis, viral suppression

Keith Alcorn | 3 month ago

Two large studies of community-based universal test and treat campaigns to promote HIV diagnos......MORE

Universal test and treat greatly improves retention in care

Keith Alcorn | 3 month ago

People who started HIV treatment in Swaziland under a universal test and treat policy were se......MORE

Donor funding for HIV stalls, increasing pressure on high-burden countries to mobilise domestic resources

Lisa Power | 3 month ago

Falling levels of donor government funding for HIV programmes threaten progress towards the 20......MORE

Unprecedented hepatitis C infection rates seen in gay men in Amsterdam PrEP programme

Gus Cairns | 3 month ago

Regular hepatitis C testing among the HIV-negative gay men and other men who have sex with men......MORE

Dolutegravir dual therapy works well for first-time HIV treatment

Liz Highleyman | 3 month ago

A two-drug combination of dolutegravir (Tivicay) and lamivudine suppressed viral load as well ......MORE

PrEP does not lower feminising hormone level in transgender women

Liz Highleyman | 3 month ago

Using Truvada (tenofovir DF/emtricitabine) for HIV prevention does not lower levels of feminis......MORE

Why are some countries slow to implement HIV treatment guidelines?

Roger Pebody | 3 month ago

Differences in countries’ economic prosperity and HIV prevalence do not explain the speed wi......MORE

World experts publish consensus statement on the science of HIV in the context of criminal law

Matthew Weait | 3 month ago

One of the most significant events at the 22nd International AIDS Conference (AIDS 2018) was t......MORE

Rapid treatment initiation and less time with detectable HIV linked to falls in new HIV diagnoses in San Francisco and Melbourne

Keith Alcorn | 3 month ago

More rapid initiation of treatment after diagnosis – and the shortening of the period with d......MORE

Dolutegravir-based ART recommended for all - if reliable contraception is available

Keith Alcorn | 3 month ago

The World Health Organization (WHO) has issued new antiretroviral treatment guidelines recomm......MORE

Brazil confirms dolutegravir is the most effective drug for first-line HIV treatment

Keith Alcorn | 3 month ago

People receiving dolutegravir-based antiretroviral treatment in Brazil’s national treatment ......MORE

Dolutegravir: update on infant neural tube defects from Botswana

Keith Alcorn | 3 month ago

Dolutegravir treatment at the time of conception is associated with a higher risk of neural tu......MORE

On-demand dosing as effective as daily dosing in first year of French PrEP study

Roger Pebody | 3 month ago

There have been no new HIV infections in the 1628 people taking part in a demonstration study ......MORE

Zero transmissions mean zero risk - PARTNER 2 study results announced

Gus Cairns | 3 month ago

The chance of any HIV-positive person with an undetectable viral load transmitting the virus t......MORE

Criminalisation of HIV high on agenda at AIDS 2018

Matthew Weait | 3 month ago

Strategies to oppose the unscientific criminalisation of HIV transmission received a high prof......MORE

The “Undetectable = Untransmittable” message goes global: I=I, N=N and B=B

Roger Pebody | 3 month ago

In Guatemala, the slogan is “Indetectable = Intransmisible” (I=I); in the Netherlands, it......MORE

Kenyan women can distribute HIV self-test kits to their sexual partners without a significant risk of intimate partner violence

Michael Carter | 4 month ago

The distribution of HIV self-testing kits by women to their sexual partners doesn't increase w......MORE

Treatment with bedaquiline significantly reduces mortality among South African people with XDR- and MDR-TB

Michael Carter | 4 month ago

Bedaquiline-based regimens are associated with large reductions in mortality in people with dr......MORE

Will an HIV vaccine that protected two-thirds of monkeys do the same for humans?

Gus Cairns | 4 month ago

Summary The Lancet last Friday published the 52-week results of APPROACH, an HIV vaccine whose......MORE

PrEP@Home pilot shows monitoring PrEP without clinic visit is feasible and acceptable

Keith Alcorn | 4 month ago

A pilot project, PrEP@Home, reduced clinic visits to one a year and demonstrated that men who ......MORE

Does U=U for breastfeeding mothers and infants? Researchers highlight unanswered questions

Keith Alcorn | 4 month ago

Research is urgently needed to provide clear recommendations on breastfeeding to mothers with ......MORE

Online HIV prevention programme reduces STIs by 40% in young men who have sex with men

Roger Pebody | 4 month ago

An interactive online programme, tailored to real-life contexts of ethnically diverse young Am......MORE

Dolutegravir durable with high rates of viral suppression in people who experienced virological failure with older integrase inhibitors

Michael Carter | 4 month ago

Antiretroviral regimens containing the integrase inhibitor dolutegravir are durable and achiev......MORE

HIV is not the only risk - using condoms or getting tested can pose risks to trust and relationships

Roger Pebody | 4 month ago

Perceptions of risk are crucial in explaining why people do or do not make use of HIV-preventi......MORE

Many taking PrEP in San Francisco not having recommended HIV and STI screens

Michael Carter | 4 month ago

Laboratory monitoring does not meet guideline standards in up to a third of people prescribed ......MORE

Condom efficacy may have been underestimated, new CDC study suggests

Gus Cairns | 4 month ago

Summary – what's different about this analysis A new meta-analysis (Johnson) of the efficacy ......MORE

Diabetes isn't adequately managed in women with HIV, says US research

Michael Carter | 4 month ago

Optimum targets for control of type 2 diabetes are achieved in only 11% of women with HIV or a......MORE

HIV self-testing is greatly preferred to clinic testing by young South African bi/gay men

Gus Cairns | 4 month ago

Summary A study that gave HIV self-testing kits out to 127 mainly young men who have sex with m......MORE

Efavirenz does not increase the risk of suicidal thoughts or depression in Ugandan adults

Keith Alcorn | 4 month ago

Treatment with the antiretroviral drug efavirenz did not increase the risk of depressive sympt......MORE

Rilpivirine better tolerated, less toxic and more durable than efavirenz in first-line ART

Michael Carter | 4 month ago

Rilpivirine is better tolerated, less toxic and more durable than efavirenz when used as part ......MORE

HIV-related factors not associated with increased risk of suicide among people with HIV in France

Michael Carter | 4 month ago

Approximately 4% of deaths among people with HIV in France are due to suicide, investigators r......MORE

Nearly a quarter of people who want PrEP currently can’t get it, UK survey finds

Gus Cairns | 4 month ago

Summary A study of pre-exposure prophylaxis (PrEP) use conducted throughout the UK by Public He......MORE

Loss of lay counsellors leads to fall in HIV testing in KwaZulu-Natal

Keith Alcorn | 4 month ago

The withdrawal of lay counsellors from primary health clinics in KwaZulu-Natal led to a sharp ......MORE

Early adopters of PrEP in Kenya and Uganda more likely to be male and older

Roger Pebody | 4 month ago

It is feasible to offer pre-exposure prophylaxis (PrEP) as part of community-wide HIV testing ......MORE

Transmitted drug resistance now less likely to harm HIV treatment options, US study finds

Keith Alcorn | 4 month ago

The rising prevalence of transmitted antiretroviral drug resistance in the United States is un......MORE

Viral suppression reduces cancer risk but does not affect common cancers

Keith Alcorn | 5 month ago

People with HIV whose viral load has been fully suppressed for at least two years have a signi......MORE

Syphilis and gonorrhoea cases at highest levels for decades, Public Health England confirms

Gus Cairns | 5 month ago

The latest sexually transmitted infections (STI) surveillance report from Public Health Englan......MORE

Frailty in men with HIV linked with bone weakness, muscle loss and large waist

Michael Carter | 5 month ago

Frailty is twice as prevalent in middle-aged and elderly HIV-positive men as in their HIV-nega......MORE

New TB cases occur rapidly among close contacts of people with pulmonary TB

Michael Carter | 5 month ago

The close contacts of people with active pulmonary tuberculosis (TB) have high rates of the di......MORE

Gay men get less HIV but more STIs after starting PrEP, meta-analysis finds

Gus Cairns | 5 month ago

A meta-analysis of 17 studies of HIV pre-exposure prophylaxis (PrEP) in gay men and other men ......MORE

Healthcare providers missing opportunities to prescribe PrEP to patients at high risk of HIV

Michael Carter | 5 month ago

Healthcare providers are missing opportunities to prescribe pre-exposure prophylaxis (PrEP) to......MORE

It’s not just HIV stigma - sexism, racism and poverty stigma commonly reported by women living with HIV in the United States

Roger Pebody | 5 month ago

Women living with HIV perceive many forms of stigma in addition to HIV-related stigma, accordi......MORE

Rapid change in Australian gay men’s safer sex practices, from consistent condom use to PrEP

Roger Pebody | 5 month ago

A rapid increase in pre-exposure prophylaxis (PrEP) use by gay men in Melbourne and Sydney has......MORE

Hepatitis B or raised liver enzymes predict liver toxicity when TB prevention drug is combined with HIV treatment

Michael Carter | 5 month ago

The risk of liver toxicity in people with HIV taking antiretroviral therapy and isoniazid prev......MORE

HIV-negative gay men uncomfortable relying on an undetectable viral load to prevent HIV

Roger Pebody | 5 month ago

Australian HIV-negative gay men express far more confidence in pre-exposure prophylaxis (PrEP)......MORE

Many young MSM discontinue PrEP

Michael Carter | 5 month ago

A third of young men who have sex with men (MSM) who take pre-exposure prophylaxis (PrEP) disc......MORE

Kidney function declines faster in men on HIV treatment than for their HIV-negative peers

Keith Alcorn | 5 month ago

Loss of kidney function in men with HIV is most strongly associated with antiretroviral therap......MORE

Potential interactions between ART and other medications present in over half of older HIV-positive people

Michael Carter | 5 month ago

Over half of older HIV-positive people are at risk of experiencing an interaction between thei......MORE

High prevalence of high-risk opioid prescribing among HIV-positive adults in the US

Michael Carter | 5 month ago

There is a high prevalence of prescription opioid use among HIV-positive people, with many ind......MORE

‘Risky when young’ or ‘risky with age’: Dutch study identifies life patterns associated with higher HIV risk in gay men

Gus Cairns | 5 month ago

A Dutch study which looked at the way gay men’s risk of HIV changed with time has used stati......MORE

Gay men having chemsex are five times more likely to have a new HIV diagnosis than other gay men

Roger Pebody | 5 month ago

Gay and bisexual men who reported engaging in chemsex (the use of specific drugs to enhance or......MORE

PrEP may make it hard to tell if someone has an HIV infection

Gus Cairns | 5 month ago

It may be very difficult to tell if someone who has just started HIV pre-exposure prophylaxis ......MORE

Dolutegravir may cause birth defects, European Medicines Agency warns

Keith Alcorn | 5 month ago

Regulatory agencies in the United States and European Union have warned that women with HIV wh......MORE

PrEP approved for adolescents in US

Liz Highleyman | 5 month ago

The US Food and Drug Administration (FDA) last week approved Truvada pre-exposure prophylaxis ......MORE

High prevalence of menopausal symptoms in women living with HIV, but very few receive treatments for them

Roger Pebody | 6 month ago

Nine in ten women living with HIV aged 45 to 60 have hot flushes and other somatic symptoms of......MORE

Do fatigue and quality of life improve after hepatitis C is cured?

Keith Alcorn | 6 month ago

Patient-reported outcomes such as fatigue, vitality and mental health improve substantially in......MORE

Taking large numbers of non-ART drugs associated with increased risk of hospitalisation and death for HIV-positive people

Michael Carter | 6 month ago

Taking large numbers of medications in addition to antiretroviral therapy (ART) is associated ......MORE

Living with HIV more than doubles the risk of erectile dysfunction in middle-aged MSM

Michael Carter | 6 month ago

Living with HIV is an independent risk factor for erectile problems among middle-aged men who ......MORE

HIV may increase the risk of skin cancer

Michael Carter | 6 month ago

People living with HIV may have an increased risk of some types of skin cancer, Danish researc......MORE

HIV cannot be transmitted by spitting, and risk from biting is negligible, says detailed case review

Michael Carter | 6 month ago

There is no risk of transmitting HIV through spitting, and the risk from biting is negligible,......MORE

Prostate cancer and lung cancer projected to be most frequent cancer diagnoses in people with HIV by 2030

Keith Alcorn | 6 month ago

Prostate and lung cancer will become the most frequently diagnosed cancers in people living wi......MORE

HIV outbreak among people who inject drugs in Glasgow now involves over 100 infections, many homeless

Michael Carter | 6 month ago

An HIV outbreak among people who inject drugs in Glasgow involves over 100 cases and is still ......MORE

Mother-to-child HIV transmission at all-time low in the UK but around two-thirds of reported cases involve women diagnosed after delivery

Michael Carter | 6 month ago

Factors such as uncertain immigration status, housing problems and intimate partner violence a......MORE

Why aren’t older people tested for HIV? Views from doctors and patients

Roger Pebody | 6 month ago

Limited knowledge of HIV and stereotypes about who may have HIV are barriers to HIV testing in......MORE

NHS England saved £10 million by switching to generic anti-HIV drugs in 2016

Roger Pebody | 6 month ago

A programme to encourage clinicians to switch people to generic antiretroviral drugs saved the......MORE

Hepatitis A causes less severe disturbances in liver function in people with HIV but illness lasts longer

Michael Carter | 6 month ago

Acute hepatitis A is less severe in people with HIV but takes longer to resolve, investigators......MORE

What are the outcomes for adults who were born with HIV?

Roger Pebody | 6 month ago

Among people who were born with HIV and have now transitioned to adult care at St Mary’s hos......MORE

Far more harms associated with crystal meth than other chemsex drugs

Roger Pebody | 6 month ago

Gay men who use crystal methamphetamine during sex are five times as likely to report a negati......MORE

HIV diagnoses in Brighton started to fall before London and for different reasons

Roger Pebody | 6 month ago

New HIV diagnoses in Brighton & Hove have fallen by half since 2013, according to a poster......MORE

1600 people taking PrEP in Scotland and Wales, almost all are gay men

Roger Pebody | 6 month ago

“Welcome to a country where we do have a full NHS-delivered programme for PrEP, with no uppe......MORE

Loneliness and isolation top list of unmet social needs among people living with HIV in the UK

Roger Pebody | 6 month ago

A survey of a large, representative sample of people attending HIV clinics in England has iden......MORE

Routine clinical use of DAAs highly effective and safe in people with HIV/HCV in Europe

Michael Carter | 7 month ago

“Real life” data from across Europe shows that direct-acting antivirals (DAAs) cure hepati......MORE

Curing hepatitis C reduces deaths and liver disease

Keith Alcorn | 7 month ago

Curing hepatitis C infection significantly reduces deaths from liver disease and reduces the ......MORE

Researchers puzzle over whether HIV accelerates cancer progression

Liz Highleyman | 7 month ago

Although people living with HIV may be diagnosed with cancer at an earlier stage because they ......MORE

Direct-acting antivirals bring fewer HCV-related liver transplants, better survival after transplantation, in Europe

Michael Carter | 7 month ago

There has been a steep fall in the number of hepatitis C virus (HCV)-related liver transplants......MORE

Eight weeks of treatment with Epclusa cured almost all people with HCV receiving opioid substitution therapy

Keith Alcorn | 7 month ago

An eight-week course of sofosbuvir/velpatasvir (Epclusa) cured almost all people with hepatiti......MORE

New affordable hepatitis C combination shows 97% cure rate

Keith Alcorn | 7 month ago

The combination of sofosbuvir and the new NS5A inhibitor ravidasvir cured 97% of people with ......MORE

First-line ART failure common among hospitalised HIV-positive people in sub-Saharan Africa

Michael Carter | 7 month ago

A large proportion of hospitalised HIV-positive people in sub-Saharan Africa have experienced ......MORE

More time with depression increases the risk of death for women with HIV

Michael Carter | 7 month ago

Increased time living with depression is associated with a higher risk of death for women with......MORE

TAF only superior to TDF when used with a boosting agent

Michael Carter | 7 month ago

The benefits of tenofovir alafenamide (TAF) over tenofovir disoproxil fumarate (TDF) may have ......MORE

Non-consensual sex is a recurrent problem in the chemsex environment

Roger Pebody | 7 month ago

The second European Chemsex Forum, recently held in Berlin, highlighted a number of difficulti......MORE

REALITY study shows which HIV-positive people with very low CD4 cell counts are at highest risk of dying soon after starting treatment

Michael Carter | 7 month ago

Mortality in people with a low CD4 cell count at the time of HIV diagnosis is associated with ......MORE

8-week course of Zepatier cures acute HCV in people with HIV

Liz Highleyman | 7 month ago

An 8-week course of grazoprevir/elbasvir (Zepatier) produced sustained virological response in......MORE

The chemsex response is reshaping sexual health services and reinventing harm reduction

Roger Pebody | 7 month ago

Chemsex has led the French community-based HIV organisation AIDES to bring two previously sepa......MORE

Loneliness and community are key to chemsex

Roger Pebody | 7 month ago

The second European Chemsex Forum, recently held in Berlin, highlighted how the perspectives o......MORE

Integrase inhibitors do not raise risk of IRIS in severely immunocompromised people

Liz Highleyman | 7 month ago

Use of an integrase inhibitor, which can bring down viral load rapidly, was not associated wit......MORE

South Africa: women may have higher rates of HIV than men because fewer men are on treatment

Gus Cairns | 7 month ago

South African researchers presenting a study at the recent Conference on Retroviruses and Oppo......MORE

Switching from abacavir to TAF improves platelet function

Liz Highleyman | 7 month ago

People who switched from an antiretroviral regimen containing abacavir to one containing tenof......MORE

Research sheds more light on cardiovascular risk in people with HIV

Liz Highleyman | 7 month ago

People with HIV are more likely to develop cardiovascular conditions, including atherosclerosi......MORE

Older people in United States more likely to have AIDS at the time of HIV diagnosis

Michael Carter | 8 month ago

People with HIV aged 60 and over in the United States are more than twice as likely to have an......MORE

Age difference in HIV infection matters - but it’s not always the younger person who is at risk

Gus Cairns | 8 month ago

A European study of men who have sex with men (MSM) presented at the recent Conference on Retr......MORE

New South Wales puts 9000 people on PrEP, achieves a one-third decline in new HIV infections

Gus Cairns | 8 month ago

The state of New South Wales in Australia has seen a fall of one-third in diagnoses of recent ......MORE

Failure of second-line ART is common in resource-limited countries, but modern third-line regimens work well

Liz Highleyman | 8 month ago

More than half of people in low- and middle-income countries may not maintain viral suppressio......MORE

Lesotho making strong progress towards 90-90-90 targets

Carole Leach-Lemens | 8 month ago

Lesotho, in spite of a high HIV prevalence of over 25%, is making substantial progress toward ......MORE

Treatment with extended-release naltrexone increases chances that HIV-positive prisoners will maintain viral suppression after release

Michael Carter | 8 month ago

Treatment with extended-release naltrexone is associated with improved viral suppression among......MORE

Very early treatment in children limits the HIV reservoir

Keith Alcorn | 8 month ago

Very early HIV treatment in infants is feasible and safe and leads to a small reservoir of inf......MORE

Isoniazid preventive therapy: do the risks outweigh the benefits in pregnant women with HIV?

Carole Leach-Lemens | 8 month ago

Isoniazid preventive therapy (IPT) during and after pregnancy in women living with HIV on anti......MORE

Powerful new PrEP and treatment drug should be effective as a small weekly pill

Gus Cairns | 8 month ago

MK-8591 or EFdA is a novel and exceptionally long-lasting and potent HIV drug, being developed......MORE

High uptake of HIV self-testing by men who have sex with men and transgender women in Burma

Roger Pebody | 8 month ago

HIV self-testing is feasible and acceptable for men who have sex with men (MSM) and transgende......MORE

Another likely case of PrEP 'breakthrough' infection reported

Gus Cairns | 8 month ago

A presentation at the recent 25th Conference on Retroviruses and Opportunistic Infections (CRO......MORE

How much 'PrEP-resistant' HIV is out there?

Gus Cairns | 8 month ago

A study presented at the recent 25th Conference on Retroviruses and Opportunistic Infections (......MORE

Efavirenz may undermine effectiveness of the vaginal ring contraceptive

Keith Alcorn | 8 month ago

The antiretroviral drug efavirenz significantly reduces the levels of both hormones in the vag......MORE

Ibalizumab, active against highly resistant HIV, now approved in US

Liz Highleyman | 8 month ago

Ibalizumab, a long-acting monoclonal antibody that prevents HIV from entering cells, is active......MORE

Statin users have lower rates of many types of cancer

Liz Highleyman | 8 month ago

Both HIV-positive and HIV-negative people who use statins to manage cardiovascular disease ris......MORE

The vaginal ring: more HOPE to the DREAM? Higher adherence and better effectiveness seen in open-label ring studies

Gus Cairns | 8 month ago

Two open-label, parallel studies of vaginal rings used to prevent HIV in women released interi......MORE

PrEP use growing in US, but not reaching all those in need

Liz Highleyman | 8 month ago

The number of people taking HIV pre-exposure prophylaxis (PrEP) in the United States is steadi......MORE

Twice-daily dolutegravir is safe and effective when used alongside TB treatment

Keith Alcorn | 8 month ago

Twice-daily dosing of dolutegravir when combined with the tuberculosis (TB) drug rifampicin i......MORE

Biktarvy combo maintains viral suppression after switching therapy

Liz Highleyman | 8 month ago

People who switched to a single-tablet regimen containing the integrase inhibitor bictegravir ......MORE

Average time from HIV diagnosis to treatment fell to six days in 2016 in San Francisco

Keith Alcorn | 8 month ago

The average time from HIV diagnosis to treatment initiation in San Francisco shrank from 35 da......MORE

Transgender women in Los Angeles are more likely to be in high HIV incidence clusters than any other group

Gus Cairns | 8 month ago

A phylogenetic study of HIV infections in Los Angeles has found that transgender women (TGW) a......MORE

Same-day treatment start improves retention in care and viral suppression in Lesotho

Keith Alcorn | 8 month ago

Starting treatment at home, on the day of diagnosis, proved acceptable in rural Lesotho and re......MORE

New HIV infections halved after scale-up of HIV treatment and circumcision in Uganda's hardest-hit district

Michael Carter | 8 month ago

The rate of new HIV infections has halved since 2011 in a Ugandan community following large in......MORE

Antiretroviral drug levels in hair strongly predict viral suppression

Liz Highleyman | 8 month ago

Antiretroviral drug levels in a sample of hair were the strongest predictor of response to HIV......MORE

One-month TB prevention regimen just as effective as 9-month regimen

Keith Alcorn | 8 month ago

A one-month course of the antibiotic rifapentine combined with isoniazid was just as effective......MORE

US genotyping survey finds rapid HIV infection rate in young and Latino gay men

Gus Cairns | 8 month ago

A US study of HIV gene sequences in networks with a particularly high HIV infection rate has f......MORE

New TB screening methods cut deaths in people with HIV

Keith Alcorn | 8 month ago

Screening for tuberculosis (TB) and intensified follow-up of TB cases in people starting antir......MORE

Experimental antibody plus TLR7 agonist maintains viral suppression in monkeys

Liz Highleyman | 8 month ago

Treatment with a broadly neutralising antibody plus an immune-stimulating drug led to long-ter......MORE

Study finds that women are much more vulnerable to HIV infection during pregnancy and in the months after giving birth

Gus Cairns | 8 month ago

A study presented today at the Conference on Retroviruses and Opportunistic Infections (CROI 2......MORE

US studies underline importance of primary care physicians for people with HIV

Keith Alcorn | 8 month ago

People with HIV who have other medical conditions such as high blood pressure or high lipids a......MORE

Intimate partner violence a major contributor to HIV epidemic among MSM in China, shows study

Michael Carter | 8 month ago

HIV prevention programmes targeted at men who have sex with men (MSM) should include intimate ......MORE

Chronic depression leads to poorer engagement with key stages of HIV care continuum, say US researchers

Michael Carter | 8 month ago

Increased time spent living with depression is associated with poorer engagement with the HIV ......MORE

HIV prevention: It’s time to stop accepting the status quo, PrEP Summit concludes

Gus Cairns | 8 month ago

The biggest barrier to HIV pre-exposure prophylaxis (PrEP) becoming more available and more wi......MORE

Smoking threatens health gains from hepatitis C treatment, US researchers warn

Keith Alcorn | 8 month ago

People with hepatitis C in the United States are at least three times more likely to smoke tha......MORE

Lymphoma treatment outcomes just as good for people with HIV

Keith Alcorn | 8 month ago

People with HIV treated for aggressive forms of non-Hodgkin lymphoma or Burkitt lymphoma appea......MORE

Severe fibrosis improves in most people after hepatitis C cure but persists in a quarter

Michael Carter | 8 month ago

Hepatitis C virus (HCV)-related liver fibrosis improves significantly in the majority of peopl......MORE

HPV16 highly prevalent among HIV-positive MSM in France and strongly associated with high-grade pre-cancerous anal lesions

Michael Carter | 8 month ago

HIV-positive gay men in France have a very high prevalence of anal infection with strains of h......MORE

PrEP does not raise lipids or alter body fat, safety study finds

Keith Alcorn | 9 month ago

Using pre-exposure prophylaxis (PrEP) does not raise lipid levels or have any substantial effe......MORE

Zambia: HIV deaths on treatment underestimated

Keith Alcorn | 9 month ago

People with HIV in Zambia were at least ten times more likely to die in the first two years af......MORE

Darunavir/ritonavir most durable boosted protease inhibitor in European patients, especially those switching treatment for any reason

Michael Carter | 9 month ago

Darunavir/ritonavir (DRV/r) is the most durable boosted protease inhibitor for antiretroviral ......MORE

High prevalence of hypertension among HIV-positive people in the US with 'missed opportunities' for its diagnosis and control

Michael Carter | 9 month ago

There is a high prevalence of hypertension among HIV-positive people in the United States and ......MORE

Communication skills training for healthcare workers improves HIV treatment adherence

Keith Alcorn | 9 month ago

People with HIV in Tanzania were more likely to report problems with non-adherence to antiretr......MORE

US regulators approve new HIV combo pill containing bictegravir

Liz Highleyman | 9 month ago

The US Food and Drug Administration (FDA) yesterday approved Biktarvy, Gilead Sciences' new si......MORE

Generic drugs for HIV treatment may save money, but barriers to prescription make savings elusive

Keith Alcorn | 9 month ago

The potential savings from prescribing generic antiretrovirals predicted by economic models ma......MORE

Reproductive health of HIV-positive women in Switzerland being neglected, says study

Michael Carter | 9 month ago

HIV-positive women in Switzerland are mainly relying on male condoms for contraception, invest......MORE

HIV-positive women starting antiretrovirals before conception have increased risk of having an infant that is small for gestational age

Michael Carter | 9 month ago

HIV-positive women who take combination antiretroviral therapy (cART) before conception have a......MORE

Harm reduction scale-up needed to eliminate HCV in people who inject drugs, European model predicts

Keith Alcorn | 9 month ago

Elimination of hepatitis C among people who inject drugs in Europe will require simultaneous s......MORE

Risk of some non-AIDS cancers greater for people with HIV than others over 50

Michael Carter | 9 month ago

The risk of several cancers increases with age for older HIV-positive people, investigators fr......MORE

NHS England seeks drug price cuts to eliminate hepatitis C by 2025

Keith Alcorn | 9 month ago

NHS England announced this week that it aims to eliminate hepatitis C by 2025 – if it can ne......MORE

Viral suppression protects against long-term liver damage caused by older HIV drugs

Michael Carter | 9 month ago

A history of treatment with some older antiretroviral drugs can have a lasting negative impact......MORE

Women with HIV less likely to receive recommended treatments for gynaecologic cancers

Michael Carter | 9 month ago

The majority of HIV-positive women diagnosed with gynaecological cancer do not receive treatme......MORE

Despite numerous risk factors for HIV, a high proportion of Malawian adolescent girls and young women don't see themselves at risk

Michael Carter | 9 month ago

Many adolescent girls and young women with multiple risk factors for infection with HIV do not......MORE

Less than half of adolescent girls and young women with HIV have suppressed viral load in eastern and southern Africa

Keith Alcorn | 9 month ago

Less than half of adolescent girls and young women with HIV in some of the countries with the......MORE

Smoking causes one in five cancers in people with HIV in North America

Michael Carter | 9 month ago

A fifth of all cancers in people receiving HIV care in North America between 2000 and 2015 was......MORE

Smoking reduces survival after liver cancer diagnosis for people with viral hepatitis

Keith Alcorn | 10 month ago

People with viral hepatitis who smoked were three times more likely to die after being diagno......MORE

Long-acting injectable ARVs are convenient and private, study participants report

Roger Pebody | 10 month ago

HIV-positive people who took injectable cabotegravir + rilpivirine every four or eight weeks a......MORE

Hepatitis C treatment highly effective in harder-to-treat people with HIV co-infection, Spanish real-life study shows

Michael Carter | 10 month ago

Hepatitis C virus (HCV) treatment using direct-acting antivirals (DAAs) is highly effective and safe......MORE

Attitudes towards men who ‘bareback’ are a barrier to wider use of PrEP

Roger Pebody | 10 month ago

Two new qualitative studies from Toronto shed light on how stigma affects the uptake of pre-exposure......MORE

Faster action on adherence is needed after viral load becomes detectable, researchers warn global treatment programmes

Keith Alcorn | 10 month ago

Low-level HIV viral load, above the limit of detection, is an important warning signal for future tr......MORE

People with HIV who are undiagnosed and those with detectable viral load less likely to use condoms, South African study finds

Michael Carter | 11 month ago

People with HIV who don't use condoms consistently are more likely to be unaware they are HIV-posit......MORE

HIV-positive transgender men in US have significant unmet medical and social needs

Michael Carter | 11 month ago

HIV-positive transgender men in the United States have significant unmet social and healthcare need......MORE

HIV drug resistance now high enough to trigger a change in first-line treatment in eastern and southern Africa

Keith Alcorn | 11 month ago

HIV drug resistance is increasing rapidly in southern and eastern Africa and Latin America and, as......MORE

ART reduces prevalence of cervical infection with high-risk HPV, pre-cancerous cell changes and cervical cancer

Michael Carter | 11 month ago

Antiretroviral therapy (ART) is associated with a lower prevalence of high-risk cervical HPV infect......MORE

ART reduces prevalence of cervical infection with high-risk HPV, pre-cancerous cell changes and cervical cancer

Michael Carter | 11 month ago

Antiretroviral therapy (ART) is associated with a lower prevalence of high-risk cervical human papi......MORE

Many Americans still get their HIV diagnosis years after infection

Liz Highleyman | 11 month ago

Many people with HIV in the United States are still being diagnosed with HIV late, and therefore no......MORE

HIV testing rate among children and adolescents boosted after caregivers receive a cash incentive

Michael Carter | 11 month ago

Children and adolescents are more likely to be tested for HIV if their parents or caregivers are of......MORE

HIV testing rate among children and adolescents boosted after care-givers receive a cash incentive

Michael Carter | 11 month ago

Children and adolescents are more likely to be tested for HIV if their parents or caregivers are of......MORE

More work and lower drug prices are needed to eliminate hepatitis C worldwide

Liz Highleyman | 11 month ago

Eliminating hepatitis C virus (HCV) as a global public health concern is feasible, but to do this m......MORE

Sofosbuvir/ledipasvir for 8 weeks cures acute HCV in people with HIV

Liz Highleyman | 11 month ago

An 8-week course of sofosbuvir/ledipasvir (Harvoni) led to a sustained response in all people with ......MORE

HIV-positive children in resource-limited settings can achieve good virological outcomes without routine viral load or CD4 cell count monitoring

Michael Carter | 11 month ago

HIV-positive children can achieve good virological outcomes without routine monitoring of CD4 cell ......MORE

Undetectable viral load at time of immunisation enhances yellow fever vaccine protection for people with HIV

Michael Carter | 11 month ago

Viral suppression at the time of immunisation is the most important determinant of long-term respon......MORE

To better target HIV prevention, identify people whose social contacts have high viral loads

Roger Pebody | 11 month ago

Rather than relying on assessment of an individual’s sexual behaviour or of ‘community viral lo......MORE

Despite reassuring data, we can’t yet say U=U for breastfeeding

Roger Pebody | 11 month ago

While effective HIV treatment greatly reduces the risk of onward transmission during breastfeeding,......MORE

Risk of chronic kidney disease and cardiovascular disease in people with HIV should be assessed together

Michael Carter | 11 month ago

People with HIV should have their risk of cardiovascular disease (CVD) and chronic kidney disease (......MORE

Schistosomiasis increases risk of infection with HIV, especially for women and is also associated with a higher HIV viral load

Michael Carter | 12 month ago

Infection with schistosome parasitic worms has an important role in HIV transmission, especially fo......MORE

Gay men’s stories of monogamy and non-monogamy: change, flexibility and tensions

Roger Pebody | 12 month ago

Although some gay men idealise monogamy, particularly in the early stages of a relationship, couple......MORE

European Cure Review concentrates on HIV therapeutic vaccines

Gus Cairns | 12 month ago

A cure for HIV would almost inevitably have to involve a vaccine to improve the body’s natural ab......MORE

Who is taking an HIV test in England and where?

Roger Pebody | 1 year ago

The range of settings in which people test for HIV has expanded significantly in recent years in En......MORE

HIV incidence is falling in English gay men, say Public Health England

Roger Pebody | 1 year ago

While several recent reports have shown that new HIV diagnoses have been falling in UK gay men, wha......MORE

Screen all HIV-positive MSM for pre-cancerous anal cell changes, say Dutch investigators

Michael Carter | 1 year ago

Younger age and shorter duration of viral suppression are risk factors for the development of high-......MORE

Nivolumab improves outcomes in liver cancer study

Liz Highleyman | 1 year ago

Nivolumab (Opdivo), a PD-1 checkpoint inhibitor that helps the immune system fight cancer, was asso......MORE

No change in cognitive function or brain structure in people taking effective HIV treatment for 2 years

Keith Alcorn | 1 year ago

People with HIV taking antiretroviral treatment who had undetectable viral load did not suffer any ......MORE

Up to a quarter of HIV-negative gay men attending three English clinics used PrEP in the last year

Gus Cairns | 1 year ago

A prospective cohort study of gay men attending three clinics in southern England – 56 Dean St an......MORE

Healthcare workers living with HIV have different motivations for disclosing or concealing their HIV status

Roger Pebody | 1 year ago

Nurses and other healthcare workers who are living with HIV have mixed reactions when they mention ......MORE

HIV diagnoses in English gay men have been falling since 2014

Gus Cairns | 1 year ago

A new analysis by Public Health England of testing rates and HIV diagnoses from all of England’s ......MORE

High HIV incidence from non-primary partners and low PEP and PREP use seen in PARTNER study

Gus Cairns | 1 year ago

HIV incidence among the HIV-negative gay men in the PARTNER 1 and 2 studies, due to sex with partne......MORE

European AIDS Clinical Society strengthens HPV vaccination advice

Keith Alcorn | 1 year ago

The European AIDS Clinical Society (EACS) has recommended HPV (human papillomavirus) vaccination fo......MORE

People with HIV more likely to adhere to their antiretroviral therapy than treatment for other chronic health problems

Michael Carter | 1 year ago

Ageing HIV-positive people have significantly higher levels of adherence to their antiretroviral th......MORE

Starting ART immediately after HIV diagnosis cuts mortality risk by two-thirds for people with high CD4 cell counts

Michael Carter | 1 year ago

People with a high CD4 cell count who start antiretroviral therapy (ART) immediately after diagnosi......MORE

Starting ART immediately after HIV diagnosis cuts mortality risk by two-thirds for patients with high CD4 cell counts

Michael Carter | 1 year ago

Patients with a high CD4 cell count who start antiretroviral therapy (ART) immediately after diagno......MORE

Swiss study examines which years gay men decided to stop consistent condom use

Gus Cairns | 1 year ago

An innovative study presented at the 16th European AIDS conference in Milan two weeks ago used a ma......MORE

Survey of dating app users finds that PrEP usage has not increased in Europe in the last year

Gus Cairns | 1 year ago

A study of men who have sex with men (MSM) conducted by the European Centre for Disease Control and......MORE

Global progress towards hepatitis C elimination still blocked by cost of treatment, lack of diagnosis

Keith Alcorn | 1 year ago

Nine countries — Australia, Brazil, Egypt, Georgia, Germany, Iceland, Japan, the Netherlands and ......MORE

UK elimination of hepatitis C in jeopardy unless more patients found

Keith Alcorn | 1 year ago

Just one in three people with hepatitis C in the United Kingdom has been diagnosed according to the......MORE

Hepatitis C test-and-treat programme reduces HCV by two-thirds among men who have sex with Men in Swiss HIV Cohort

Keith Alcorn | 1 year ago

A systematic policy of test-and-treat cured 99% of men who have sex with men with hepatitis C in th......MORE

Curing hepatitis C with DAAs linked to 71% reduction in liver cancer

Liz Highleyman | 1 year ago

People who achieved a sustained response to hepatitis C treatment lowered their risk of hepatocellu......MORE

High rate of hepatitis C reinfection in German men who have sex with men

Keith Alcorn | 1 year ago

Around one in seven gay and bisexual men cured of hepatitis C at major treatment centres in German......MORE

Symtuza as effective as multi-pill combination in previously untreated people with HIV

Keith Alcorn | 1 year ago

The single-pill combination of darunavir, cobicistat, tenofovir alafenamide and emtricitabine (Symt......MORE

Fostemsavir controls viral load in half of people with highly drug-resistant HIV

Keith Alcorn | 1 year ago

Fostemsavir, a new experimental attachment inhibitor, suppressed viral load in over half of partici......MORE

Hepatitis C halved in Spanish people living with HIV in one year due to treatment

Keith Alcorn | 1 year ago

Spain is making dramatic progress towards eliminating hepatitis C in people living with HIV because......MORE

People with HIV still expect a lower quality of life than their negative peers, European survey finds

Gus Cairns | 1 year ago

A study commissioned by the drug company Gilead Sciences and conducted in five European countries h......MORE

New EACS treatment guidelines

Keith Alcorn | 1 year ago

Everyone with HIV and HCV co-infection should receive direct-acting antiviral treatment for hepatit......MORE

How a London clinic reduced new HIV infections by 90% and why more European cities can do the same

Keith Alcorn | 1 year ago

Scaling up HIV testing to reduce undiagnosed HIV infection requires a fundamental re-ordering of HI......MORE

ABX464 reduces HIV reservoir but doesn’t delay viral rebound

Keith Alcorn | 1 year ago

ABX464, a new drug that stimulates the clearance of HIV from infected cells, reduces the reservoir ......MORE

Boosted protease inhibitor and lamivudine provides effective maintenance treatment

Keith Alcorn | 1 year ago

HIV maintenance treatment with two drugs, a boosted protease inhibitor and lamivudine, is just as e......MORE

Daily aspirin therapy linked to lower liver cancer risk

Liz Highleyman | 1 year ago

People with hepatitis B virus (HBV) who took an aspirin a day – often recommended to help prevent......MORE

Hepatitis C testing linked to reduced opioid use among people who inject drugs

Liz Highleyman | 1 year ago

Getting tested for hepatitis C virus (HCV) was associated with reduced drug use, especially among t......MORE

Maviret cures most people with HCV genotype 3 and those with cirrhosis

Liz Highleyman | 1 year ago

Glecaprevir and pibrentasvir, the two drugs in the recently approved Maviret co-formulation, demons......MORE

HCV infection is rising among HIV-positive gay men in San Diego

Liz Highleyman | 1 year ago

Hepatitis C incidence is increasing among gay and bisexual men living with HIV in San Diego, accord......MORE

Hepatitis C cure leads to improved quality of life

Liz Highleyman | 1 year ago

People who were cured of hepatitis C with direct-acting antivirals (DAAs) had sustained improvement......MORE

A year of generic PrEP could recoup its own cost within five years if effectiveness is high, Public Health England model finds

Gus Cairns | 1 year ago

A cost-effectiveness model developed by Public Health England finds that just one year’s worth of......MORE

PrEP would save the NHS money, in numerous scenarios

Roger Pebody | 1 year ago

A PrEP programme for men who have sex with men in the UK would not only be cost-effective, but actu......MORE

Restrictions on free DAA access in many European countries contrary to guidelines and undermine HCV elimination targets, say researchers

Michael Carter | 1 year ago

The restrictions which many European countries impose on free/reimbursed access to hepatitis C viru......MORE

MSM in London diagnosed with early syphilis are a priority group for PrEP, suggests UK study

Michael Carter | 1 year ago

Gay and other men who have sex with men (MSM) recently diagnosed with early syphilis are a priority......MORE

Symtuza protease inhibitor regimen maintains viral suppression for a year

Liz Highleyman | 1 year ago

People who switched from a multi-pill antiretroviral regimen to the first one-pill, once-daily regi......MORE

Long-acting monoclonal antibody effective against multidrug-resistant HIV

Liz Highleyman | 1 year ago

Ibalizumab, a long-acting monoclonal antibody that prevents HIV from entering cells, maintained vir......MORE

Rapid fibrosis progression in large proportion of HIV-positive gay men after acute HCV

Michael Carter | 1 year ago

Over a third of HIV-positive gay men develop significant liver fibrosis after an episode of acute h......MORE

Impact of side-effects on retention in HIV care is underestimated, African study suggests

Keith Alcorn | 1 year ago

The impact of drug side-effects on retention in HIV care is probably being underestimated, accordin......MORE

Impact of side effects on retention in HIV care is underestimated, African study suggests

Keith Alcorn | 1 year ago

The impact of drug side effects on retention in HIV care is probably being underestimated, accordin......MORE

Many gay/bisexual men currently taking PrEP would switch to injectable forms of the therapy should it become available

Michael Carter | 1 year ago

Approximately a third of gay and bisexual men who are currently taking oral (tenofovir/emtricitabin......MORE

People with HIV/HCV co-infection have an increased risk of cardiovascular disease compared to people with HIV alone

Michael Carter | 1 year ago

People with HIV/hepatitis C virus (HCV) co-infection are between a quarter and a third more likely ......MORE

HIV diagnoses in the UK fell in gay men last year for the first time since the mid-1990s, Public Health England confirms

Gus Cairns | 1 year ago

The 2016 HIV surveillance figures released by Public Health England (PHE) today reveal that what ha......MORE

Virally-suppressed people have “effectively no risk” of transmitting HIV, says US CDC: but how many are suppressed?

Gus Cairns | 1 year ago

The US Centers for Disease Control and Prevention (CDC) used 27 September, National Gay Men’s HIV......MORE

Virally suppressed people have “effectively no risk” of transmitting HIV, says US CDC: but how many are suppressed?

Gus Cairns | 1 year ago

The US Centers for Disease Control and Prevention (CDC) used 27 September, National Gay Men’s HIV......MORE

Drinking three or more cups of coffee a day halves the risk of dying for people with HIV/HCV co-infection

Michael Carter | 1 year ago

Drinking three or more cups of coffee a day halves the risk of death from any cause for people with......MORE

Amsterdam PrEP failure patient had unusual course of HIV infection

Gus Cairns | 1 year ago

At last February’s Conference on Retroviruses and Opportunistic Infections (CROI), Dutch clinicia......MORE

Depression highly prevalent among people living with HIV in sub-Saharan Africa

Michael Carter | 1 year ago

Depression is very common among people living with HIV (PLHIV) in sub-Saharan Africa (SSA), accordi......MORE

US FDA approves nivolumab immunotherapy for liver cancer

Liz Highleyman | 1 year ago

The US Food and Drug Administration (FDA) last week granted accelerated approval for nivolumab (Opd......MORE

HIV diagnoses on the rise among over-50s in Europe

Keith Alcorn | 1 year ago

Just over one in six people diagnosed with HIV in Europe between 2004 and 2015 was over 50 years of......MORE

People living with HIV in the UK not receiving appropriate monitoring of heart disease risk

Michael Carter | 1 year ago

The majority of HIV-positive people in the UK are not receiving recommended monitoring of cardiovas......MORE

Australian clinic records show significant reduction in duration of infectiousness in HIV-positive gay men from 2007-2016

Michael Carter | 1 year ago

The period during which HIV-positive men who have sex with men (MSM) are potentially infectious fel......MORE

Marathon training is safe for people with HIV

Michael Carter | 1 year ago

Marathon run training is safe for people with HIV, investigators from Germany report in BMC Infecti......MORE

Does drug injection equipment other than syringes transmit hepatitis C?

Liz Highleyman | 1 year ago

Sharing drug preparation paraphernalia may not significantly contribute to hepatitis C virus (HCV) ......MORE

Smokers with HIV doing well on treatment now at greater risk of lung cancer than AIDS

Keith Alcorn | 1 year ago

People living with HIV on antiretroviral treatment with fully suppressed viral load who smoke are m......MORE

San Francisco annual report shows continued drop in new HIV infections

Liz Highleyman | 1 year ago

The San Francisco Department of Public Health has released its HIV Epidemiology Annual Report for 2......MORE

High prices of DAAs mean there's been little progress towards achieving WHO target of eliminating HCV by 2030

Michael Carter | 1 year ago

Only a handful of countries are on course to achieve the World Health Organization (WHO) target of......MORE

Study documents changing opinion among Italian doctors about PrEP

Gus Cairns | 1 year ago

A survey of Italian infectious disease physicians working with HIV, conducted in 2015 but only publ......MORE

New guidelines recommend that women avoid tenofovir & emtricitabine during pregnancy

Keith Alcorn | 1 year ago

Women should be offered the choice to avoid treatment with tenofovir and emtricitabine during pregn......MORE

New US PrEP cost-effectiveness model finds drug prices will need to drop substantially if HIV risk rises, or if adherence is only moderate

Gus Cairns | 1 year ago

A new US model of the cost-effectiveness of pre-exposure prophylaxis (PrEP) for men who have sex wi......MORE

Maraviroc matches boosted protease inhibitor treatment over 96 weeks

Michael Carter | 1 year ago

Treatment with maraviroc (Celsentri/Selzentry) is associated with durable HIV suppression and a fav......MORE

What is going on in gay men’s lives when they acquire HIV?

Roger Pebody | 1 year ago

Gay men in England who have recently become HIV positive describe a complex web of factors which ma......MORE

No new HIV infections among Kaiser PrEP users, but data shows missed opportunities

Liz Highleyman | 1 year ago

No new HIV infections have occurred among nearly 5000 people who started Truvada for pre-exposure p......MORE

Lipids improved by switching from ritonavir to cobicistat as a booster for darunavir

Michael Carter | 1 year ago

Switching from ritonavir to cobicistat is associated with significant improvements in cholesterol a......MORE

Case reports of severe dolutegravir-related depression

Michael Carter | 1 year ago

Severe depression can be a side-effect of treatment with the anti-HIV drug dolutegravir. In HIV Med......MORE

Experts concur that intermittent oral PrEP probably won’t work for women

Gus Cairns | 1 year ago

Two presentations at the recent International AIDS Society Conference on HIV Science (IAS 2017) in ......MORE

Experts concur that event-related oral PrEP probably won’t work for women

Gus Cairns | 1 year ago

Two presentations at the recent International AIDS Society Conference on HIV Science (IAS 2017) in ......MORE

Taking dolutegravir in the morning may avert insomnia

Keith Alcorn | 1 year ago

Italian doctors say that sleeplessness after taking the integrase inhibitor dolutegravir occurred m......MORE

The availability of direct-acting antivirals is reducing disparities in the uptake of hepatitis C treatment

Roger Pebody | 1 year ago

An analysis from British Columbia, Canada shows that older people, individuals with HIV co-infectio......MORE

The availability of directly acting antivirals is reducing disparities in the uptake of hepatitis C treatment

Roger Pebody | 1 year ago

An analysis from British Columbia, Canada shows that older people, individuals with HIV co-infectio......MORE

Who are trans women acquiring HIV from?

Gus Cairns | 1 year ago

There is a lot we don’t know about trans women’s HIV risk, why they are so vulnerable to HIV an......MORE

One in seven people offered PrEP in African study start it immediately

Gus Cairns | 1 year ago

One in seven (14%) of people offered PrEP in a large community study of enhanced HIV testing and tr......MORE

What is “successful ageing” for people living with HIV?

Roger Pebody | 1 year ago

When Canadian researchers asked HIV-positive people over the age of 50 how they would define “suc......MORE

New South Wales reports record drop in HIV diagnoses: fewest this year since records began

Gus Cairns | 1 year ago

Australia’s most populous state, New South Wales (NSW), has reported a steep drop in HIV diagnose......MORE

No evidence of reduced efficacy or increased side-effects when patients switch to generic drugs, comparison study finds

Roger Pebody | 1 year ago

An analysis of 440 people switched to generic antiretroviral drugs at an Italian clinic and a match......MORE

Trans women wary of antiretroviral drug and hormone interactions

Liz Highleyman | 1 year ago

Transgender women living with HIV may be hesitant to use antiretroviral therapy (ART) or not take i......MORE

Liver fibrosis speeds up around the menopause in women with HIV and HCV co-infection

Michael Carter | 1 year ago

Menopause is associated with accelerated liver fibrosis in women with HIV and hepatitis C virus (HC......MORE

People with HIV are at risk for liver fibrosis and steatosis

Liz Highleyman | 1 year ago

Metabolic syndrome, type 2 diabetes and obesity are risk factors for the development of liver fibro......MORE

Switching from efavirenz to raltegravir leads to significant improvements in fatty liver disease in people with HIV

Michael Carter | 1 year ago

Switching to raltegravir from efavirenz is associated with significant improvements in liver steato......MORE

Peripheral artery disease more common in people with HIV with lower CD4 counts

Keith Alcorn | 1 year ago

Peripheral artery disease, one of the most common forms of cardiovascular disease, occurs more freq......MORE

PrEP use in US exceeds 100,000 in Gilead pharmacy survey

Liz Highleyman | 1 year ago

An estimated 120,000 people in the US have started Truvada for pre-exposure prophylaxis (PrEP) sinc......MORE

Incidence of anal cancer has already peaked among HIV-positive gay men; reductions can be achieved with expanded ART coverage and screening

Michael Carter | 1 year ago

The incidence of anal cancer among HIV-positive gay men peaked in 2009 and will decline substantial......MORE

Treatment with DAAs reduces the risk of mortality in the first 18 months after the completion of treatment

Michael Carter | 1 year ago

For the first time, a large study has demonstrated that treatment with direct-acting antivirals (DA......MORE

Switch from boosted protease inhibitor to dolutegravir reduces lipids in people with HIV at higher risk of heart disease

Keith Alcorn | 1 year ago

Switching from a boosted protease inhibitor to the integrase inhibitor dolutegravir was associated ......MORE

Boosted darunavir plus lamivudine matches three-drug regimen

Keith Alcorn | 1 year ago

A combination of darunavir/ritonavir and lamivudine was just as effective as the same combination p......MORE

European and US regulators approve AbbVie's new combo for all hepatitis C genotypes

Liz Highleyman | 1 year ago

The European Commission and the US Food and Drug Administration (FDA) last week approved AbbVie's n......MORE

PrEP demand in England is rapidly accelerating – and most will want to join the trial

Gus Cairns | 1 year ago

A survey of people currently using pre-exposure prophylaxis (PrEP) has found that PrEP use has rapi......MORE

Why curing HIV may be like curing cancer – and may be as difficult

Gus Cairns | 1 year ago

For the last few years, a specialist symposium on HIV cure research has preceded the International ......MORE

What marks out HIV controllers from others?

Gus Cairns | 1 year ago

What if we are asking the wrong, question, though? What if trying to destroy or at least expose and......MORE

Can we achieve a complete HIV cure in more patients?

Gus Cairns | 1 year ago

What all the different approaches discussed in the previous report have in common is to put HIV inf......MORE

VRC01 antibody can delay but not prevent viral rebound after interruption of early treatment

Liz Highleyman | 1 year ago

A broadly neutralising antibody modestly delayed the resurgence of viral replication following inte......MORE

Long-acting NRTI shows promise for HIV treatment and PrEP

Liz Highleyman | 1 year ago

A single oral dose of MK-8591, a long-acting antiretroviral in a novel drug class, suppressed HIV f......MORE

Stillbirth more frequent in women with HIV in UK and Ireland than in general population

Carole Leach-Lemens | 1 year ago

The stillbirth rate among women living with HIV in the UK and Ireland from 2007 to 2015 was more th......MORE

US HIV funding decisions on PEPFAR in 2017 will have critical effect on ability to reach 90-90-90 goals

Keith Alcorn | 1 year ago

A withdrawal of United States funding for HIV treatment and prevention in sub-Saharan Africa could ......MORE

First protease inhibitor combination pill maintains viral suppression

Liz Highleyman | 1 year ago

The first once-daily single-tablet regimen containing a protease inhibitor maintained viral suppres......MORE

Adolescents with HIV do better in more prosperous African countries, even with treatment

Carole Leach-Lemens | 1 year ago

Adolescents who acquired HIV perinatally were less likely to die, grew faster and had better immune......MORE

France’s next PrEP study aims to assess the wider impact of PrEP on the HIV epidemic

Roger Pebody | 1 year ago

France is launching a new study which will enrol 3000 new pre-exposure prophylxis (PrEP) users over......MORE

Dutch study finds out whether gay men prefer daily or on-demand PrEP

Gus Cairns | 1 year ago

In Europe, whether through national programmes or in trials, people are more often than not being g......MORE

Long-acting cabotegravir injection shows promise for HIV prevention

Liz Highleyman | 1 year ago

A long-acting injectable formulation of cabotegravir given every 8 weeks produces high enough drugs......MORE

Doravirine combination pill looks good for initial HIV treatment

Liz Highleyman | 1 year ago

A single-tablet regimen containing the next-generation NNRTI doravirine reduced HIV viral load as m......MORE

Acute kidney injury ‘uncommon’ but unpredictable on tenofovir and ritonavir

Gus Cairns | 1 year ago

Doctors need to monitor patients regularly for kidney function if they are taking tenofovir, especi......MORE

Countries and donors should aim for new $90-$90-$90 target on HIV, hepatitis, TB drug prices, study shows

Keith Alcorn | 1 year ago

HIV, hepatitis B and C and tuberculosis can each be treated for less than $90 a year where generic ......MORE

Medical male circumcision for HIV has benefits for women too

Roger Pebody | 1 year ago

South African women whose most recent sexual partner was circumcised are less likely to have HIV, s......MORE

Demonstration projects explore the feasibility of PrEP for adolescents and young women in South Africa

Roger Pebody | 1 year ago

One of the first studies to explore the acceptability, safety and use of pre-exposure prophylaxis (......MORE

Ipergay trial: PrEP still protected people who had less sex and used it less often

Gus Cairns | 1 year ago

A substudy of the French Ipergay trial of ‘on-demand’ PrEP has found that PrEP was just as effe......MORE

Another HIV vaccine efficacy trial will start this year

Gus Cairns | 1 year ago

A year ago, one of the biggest pieces of prevention news at the Durban International AIDS Conferenc......MORE

Glecaprevir/pibrentasvir is effective for people with HIV/HCV co-infection

Liz Highleyman | 1 year ago

AbbVie's new pangenotypic regimen combining glecaprevir and pibrentasvir cured almost all HIV-posit......MORE

90-90-90 progress in southern Africa: HIV testing gap needs to be closed in young people and men

Keith Alcorn | 1 year ago

Three African countries with high burdens of HIV infection are achieving very high levels of HIV tr......MORE

Can self-testing engage 'hard to reach' men with HIV testing?

Roger Pebody | 1 year ago

Adding HIV self-testing as an additional option to a door-to-door programme offering HIV testing in......MORE

Integrase inhibitors not causing higher rates of adverse birth outcomes, Botswana and French studies show

Carole Leach-Lemens | 1 year ago

Dolutegravir-based antiretroviral therapy (ART) started in pregnancy is as safe as efavirenz-based ......MORE

New guidance says start HIV treatment within 7 days of diagnosis – but is everyone ready?

Keith Alcorn | 1 year ago

Everyone diagnosed with HIV should be offered the option to start treatment within seven days of di......MORE

International study of gay couples reports no transmissions from an HIV-positive partner on treatment

Gus Cairns | 1 year ago

A study of 343 gay couples, where one partner had HIV and the other did not, has not found a single......MORE

New integrase inhibitor bictegravir works well for first-line HIV treatment

Liz Highleyman | 1 year ago

A single-tablet regimen containing the experimental integrase inhibitor bictegravir was as effectiv......MORE

Hepatitis C treatment is effective and feasible in Africa

Liz Highleyman | 1 year ago

Treatment for hepatitis C in sub-Saharan Africa can produce cure rates as high as those seen in ind......MORE

High uptake of HIV self testing by female sex workers in African countries

Roger Pebody | 1 year ago

A year ago there was virtually no evidence on the acceptability and feasibility of HIV self testing......MORE

South African child has controlled HIV off treatment for 8.5 years

Keith Alcorn | 1 year ago

A nine-year-old South African child who was diagnosed with HIV infection at one month of age and r......MORE

Programme to provide free self tests helps gay men to test for HIV more often

Roger Pebody | 1 year ago

Providing free HIV self-testing kits to gay and bisexual men is an effective way to increase the fr......MORE

Less frequent clinic visits for HIV care: fine tuning needed

Keith Alcorn | 1 year ago

Shifts to less frequent clinic visits and medication pick-ups to free up healthcare resources and ......MORE

Improved treatment for cryptococcal meningitis in HIV could save thousands of lives – if generic drug becomes available

Keith Alcorn | 1 year ago

Urgent action is needed to improve access to the antifungal drug flucytosine, say investigators, fo......MORE

Swaziland: new infections halved in five years as HIV treatment scales up

Keith Alcorn | 1 year ago

New HIV infections have halved in Swaziland since 2011 at the same time as the proportion of people......MORE

Long-acting cabotegravir + rilpivirine injection shows good results at 96 weeks

Liz Highleyman | 1 year ago

Two long-acting injectable antiretrovirals, cabotegravir and rilpivirine, administered once every 4......MORE

London gonorrhoea rates fall, and HIV rates falling in Australia as more join PrEP demo

Gus Cairns | 1 year ago

Gonorrhoea diagnoses among gay men attending the largest STI clinic in the UK at 56 Dean Street in ......MORE

World on track to reach the 90-90-90 targets for HIV treatment by 2020

Keith Alcorn | 1 year ago

The world is on track to reach global targets for reducing AIDS deaths and HIV treatment access by ......MORE

WHO recommends package of tests, treatment and prevention for 'urgent need' people with HIV with low CD4 counts

Keith Alcorn | 1 year ago

A new package of measures to ensure rapid initiation of antiretroviral treatment and diagnosis of o......MORE

Few people with HIV starting raltegravir and dolutegravir change therapy because of side-effects

Michael Carter | 1 year ago

Only a few people starting an integrase inhibitor discontinue the treatment during the first year o......MORE

US regulator approves Gilead's Vosevi combo pill for hepatitis C retreatment

Liz Highleyman | 1 year ago

On 18 July the US Food and Drug Administration (FDA) approved Gilead Sciences' Vosevi, a new once-d......MORE

US regulators approves Gilead's Vosevi combo pill for hepatitis C re-treatment

Liz Highleyman | 1 year ago

On July 18 the US Food and Drug Administration (FDA) approved Gilead Sciences' Vosevi, a new once-d......MORE

Many people living with HIV at high risk of cardiovascular disease are not on statins

Michael Carter | 1 year ago

Only half of HIV-positive patients at a Chicago clinic eligible for statin therapy according to the......MORE

People treated with atazanavir had lower risk of stroke and heart attack

Keith Alcorn | 1 year ago

People who started HIV treatment with a drug combination containing atazanavir (Reyataz) were signi......MORE

Gay men using HIV self-tests promptly seek confirmatory testing and linkage to care, New York data suggests

Roger Pebody | 1 year ago

Data from the partner services programme in New York City suggests that gay men who have previously......MORE

Proton pump inhibitors may blunt CD4 cell gains, cause immune activation, in people with HIV

Keith Alcorn | 1 year ago

Proton pump inhibitors should be used with caution in people with HIV, US researchers say, after fi......MORE

Non-alcoholic fatty liver disease common in people living with HIV – metabolic disorders are key risk factors

Michael Carter | 1 year ago

Over a third of people with HIV have non-alcoholic fatty liver disease (NAFLD) in the absence of he......MORE

High uptake of home-based HIV testing in Zambia, but repeat visits needed to get close to universal coverage

Roger Pebody | 1 year ago

Preliminary results from PopART, a large-scale study of a universal test and treat approach to slow......MORE

Frailty is associated with loss of bone mineral density in middle-aged HIV-positive men and women

Michael Carter | 1 year ago

Frailty is associated with loss of bone mineral density (BMD) in HIV-positive people, investigators......MORE

Curing hepatitis C improves diabetes control

Keith Alcorn | 1 year ago

Curing hepatitis C infection with direct-acting antiviral treatment improves diabetes control in pe......MORE

Viral load as low as 400 copies/ml six months after starting ART is associated with a significant ten-year mortality risk

Michael Carter | 1 year ago

A viral load as low as 400 copies/ml six months after starting HIV therapy is associated with a sub......MORE

Hepatitis A oubreak in gay and bisexual men in Europe is growing

Keith Alcorn | 1 year ago

New cases of hepatitis A cases have soared in Western Europe over the past six months as a result o......MORE

Hepatitis A outbreak in gay and bisexual men in Europe is growing

Keith Alcorn | 1 year ago

New cases of hepatitis A cases have soared in Western Europe over the past six months as a result o......MORE

San Francisco task force releases first hepatitis C estimates

Liz Highleyman | 1 year ago

End Hep C SF, a consortium of public health workers, medical providers, advocates and people living......MORE

Study identifies serious gaps in treatment and care of HIV-positive adolescents in sub-Saharan Africa

Michael Carter | 1 year ago

Healthcare providers in sub-Saharan Africa are struggling to provide services for HIV-positive adol......MORE

Why are women lost from HIV care during pregnancy? Malawi study shows social support and counselling are critical

Keith Alcorn | 1 year ago

Lack of social support after diagnosis and inadequate counselling about HIV treatment and HIV disc......MORE

HIV drug resistance becoming more common in Zambian infants

Keith Alcorn | 1 year ago

The proportion of infants with HIV who had drug resistance at the time of HIV diagnosis almost doub......MORE

New pangenotypic hepatitis C drug combinations recommended for approval in the European Union

Keith Alcorn | 1 year ago

Two new pangenotypic direct-acting antiviral combinations have received positive opinions from the ......MORE

Many Western European countries close to achieving UNAIDS 90-90-90 targets

Michael Carter | 1 year ago

Countries in Western and Southern Europe are well on their way to meeting the UNAIDS 90-90-90 targe......MORE

HIV has a similar impact to diabetes on heart disease risk

Keith Alcorn | 1 year ago

Living with HIV carries the same lifetime risk of cardiovascular disease as having diabetes, even a......MORE

Researchers say rule out depression, anxiety, unemployment and other stresses before blaming cognitive impairment for everyday difficulties

Michael Carter | 1 year ago

One in five people living with HIV in a European study reported a decline in everyday functioning a......MORE

Risk score can identify which HIV-positive people with controlled viral load are at greatest risk of neurocognitive decline

Michael Carter | 1 year ago

Four factors are associated with neurocognitive decline in people living with HIV with an undetecta......MORE

Experts question Cochrane review of hepatitis C treatment

Keith Alcorn | 1 year ago

A systematic review of hepatitis C direct-acting antiviral studies published by the Cochrane Collab......MORE

HIV drug resistance testing not a priority for resource-limited settings, trial finds

Keith Alcorn | 1 year ago

Resistance testing is unlikely to improve the effectiveness of second-line HIV treatment in resourc......MORE

Fractures occur at an earlier age among men with HIV

Michael Carter | 1 year ago

The incidence of fractures begins to rise a full decade earlier in HIV-positive men compared to the......MORE

High prevalence of tobacco use among HIV-positive individuals in low- and middle-income countries

Michael Carter | 1 year ago

There is a high prevalence of tobacco use among HIV-positive adults in low- and middle-income count......MORE

Taking PrEP has a profound impact on gay men’s sexual health and wellbeing

Roger Pebody | 1 year ago

Men who have sex with men (MSM) in Seattle who had recently begun to take pre-exposure prophylaxis ......MORE

Swiss Grindr survey finds 50% want to use PrEP in the next six months

Gus Cairns | 1 year ago

A survey of Swiss gay men and men who have sex with men recruited through the Grindr networking app......MORE

Point-of-care CD4 counts improve linkage to HIV care in Kenya

Keith Alcorn | 1 year ago

Carrying out a point-of-care CD4 count immediately after a person was diagnosed with HIV by home-ba......MORE

MSM, especially if HIV-positive, have an increased risk of meningococcal disease, according to US research

Michael Carter | 1 year ago

Men who have sex with men (MSM) have an increased risk of meningococcal disease, investigators from......MORE

Belgium, Portugal and Brazil will provide PrEP through their health services; Morocco announces a PrEP study

Gus Cairns | 1 year ago

In the last two weeks, several countries have announced that they will soon launch pre-exposure pro......MORE

Six-question risk score can identify HIV-positive gay men needing testing for acute hepatitis C

Roger Pebody | 1 year ago

Six questions can identify HIV-positive gay men who are at elevated risk of having acute (recent) h......MORE

Young women in Zimbabwe in sexual relationships with older men have an especially high risk of infection with HIV

Michael Carter | 1 year ago

Young women in Zimbabwe have an especially high risk of infection with HIV if they have a sexual pa......MORE

HIV treatment targets for people who inject drugs will be missed without focus on rights, privacy and prisons

Susie McLean | 1 year ago

Reaching ambitious HIV treatment targets for people who use drugs requires efforts to protect priv......MORE

High frequency of recurrent high-grade pre-cancerous anal lesions in HIV-positive MSM

Michael Carter | 1 year ago

A high proportion of HIV-positive men who have sex with men (MSM) successfully treated for high-gra......MORE

Agreements with cash incentives boost patient adherence to HIV therapy and rates of viral suppression

Michael Carter | 1 year ago

Patients who enter into a contract with their HIV healthcare provider to receive cash incentives in......MORE

Heroin combined with fentanyl is driving overdose crisis in US

Liz Highleyman | 1 year ago

New sources of heroin and increasing adulteration with fentanyl and other stronger analogues are co......MORE

Injecting drug use increases worldwide, but no increases in needle and syringe programmes

Susie McLean | 1 year ago

Despite reports of expanding rates of injecting drug use in a new list of countries around the worl......MORE

Indonesian buyers club helps people obtain generic hepatitis C treatment

Liz Highleyman | 1 year ago

A community-led buyers club in Indonesia has helped more than 100 people get generic direct-acting ......MORE

Pet care can connect people to health and harm reduction services

Liz Highleyman | 1 year ago

Providing free veterinary care can be a good way to bring homeless and marginally housed people int......MORE

Use of psychedelic drugs may reduce the risk of suicide in female sex workers

Liz Highleyman | 1 year ago

Women sex workers who used psychedelic drugs such as LSD were less likely to think about or attempt......MORE

People with HIV have impaired respiratory health, even when viral load is undetectable

Michael Carter | 1 year ago

HIV-positive people have impaired respiratory health, even when they have viral suppression with an......MORE

Canadian Minister of Health opens International Harm Reduction conference amid controversy over overdose deaths

Susie Mclean | 1 year ago

The 25th International Harm Reduction Conference (HR17) in Montréal, Canada, kicked off with a dra......MORE

People who use drugs may use cannabis and drug cocktails as a form of harm reduction

Liz Highleyman | 1 year ago

People who use drugs have come up with innovative strategies that help them reduce harm, including ......MORE

Many physicians are wary of providing HIV PrEP for young people

Liz Highleyman | 1 year ago

Only about a third of family practice and paediatric providers said they would be likely to prescri......MORE

Hepatitis C virus reinfection is uncommon after being cured with DAAs

Liz Highleyman | 1 year ago

Most people on opiate substitution therapy were successfully treated for hepatitis C with an interf......MORE

Overamping is a common problem among people who use stimulants

Liz Highleyman | 1 year ago

Overdosing on stimulants such as methamphetamine – known as 'overamping' – is an under-recognis......MORE

Combining drug addiction treatment and perinatal HIV prevention leads to good outcomes in Kenya

Liz Highleyman | 1 year ago

An integrated programme offering medication-assisted drug addiction treatment and services aimed at......MORE

Hydromorphone works as well as heroin-assisted drug addiction treatment

Liz Highleyman | 1 year ago

Hydromorphone was as effective as pharmaceutical heroin for opioid addiction treatment, but it was ......MORE

Drug checking reveals high levels of fentanyl contamination in Vancouver street drugs

Liz Highleyman | 1 year ago

A pilot project to check the purity of drugs at Vancouver's Insite safe injection facility found th......MORE

AA amyloidosis is an unrecognised problem among people who inject drugs

Liz Highleyman | 1 year ago

AA amyloidosis, a condition resulting from skin and soft tissue infections that can lead to kidney ......MORE

Life expectancy now near-normal in people with CD4 counts over 350 a year after starting therapy

Gus Cairns | 1 year ago

A large study of 88,504 people with HIV on antiretroviral therapy (ART), published in the Lancet jo......MORE

Protease inhibitor drug suppresses HIV in semen more slowly than drugs from other classes

Gus Cairns | 1 year ago

Protease inhibitors may not be the best class of drug for people newly diagnosed with HIV to start ......MORE

MDR-TB numbers could keep growing despite improved treatment

Keith Alcorn | 1 year ago

Up to one-in-three tuberculosis cases in Russia could be multidrug resistant by 2040, and one-in-ei......MORE

MDR TB numbers could keep growing despite improved treatment

Keith Alcorn | 1 year ago

Up to one in three tuberculosis cases in Russia could be multi-drug resistant by 2040, and one in e......MORE

Switching from efavirenz to lopinavir/ritonavir has no meaningful impact on neurological function, says UK study

Michael Carter | 1 year ago

Switching from efavirenz does not significantly improve the neurological function of patients takin......MORE

Undocumented migrants more likely to be lost to follow-up and have poor virological outcomes after starting ART, Milan study confirms

Michael Carter | 1 year ago

Undocumented migrants living with HIV have especially poor rates of retention in care and virologic......MORE

Besifovir and tenofovir exalidex look promising as new hepatitis B drugs

Liz Highleyman | 1 year ago

Two investigational nucleotide analogue antivirals were shown to be active against hepatitis B viru......MORE

Naloxone is a heath intervention that can’t be effectively provided without the knowledge and social connections of people who inject drugs

Roger Pebody | 1 year ago

Programmes to provide naloxone, a drug that reverses the effects of opiate overdose, are successful......MORE

Fear of stigma is prompting young South Africans to seek early HIV treatment

Keith Alcorn | 1 year ago

Young South Africans are strongly motivated to seek HIV testing and treatment by a desire to mainta......MORE

Increased screening for syphilis boosts detection of early latent infections among Australian gay men

Michael Carter | 1 year ago

Increased syphilis testing among gay men increased detection of early latent infections and was acc......MORE

Avoiding false positives: rapid HIV tests vary in their accuracy, so need to be used in combination

Roger Pebody | 1 year ago

An evaluation of eight widely used rapid diagnostic tests used in a variety of African countries by......MORE

Triple combination cures most hepatitis C patients with prior DAA treatment failure

Liz Highleyman | 1 year ago

Almost all people with genotype 1 hepatitis C who were previously unsuccessfully treated with a cou......MORE

Early ART highly acceptable and achieves excellent rates of viral suppression among young South African women

Michael Carter | 1 year ago

Early antiretroviral therapy (ART) is highly acceptable to the majority of young women with HIV in ......MORE

EASL releases updated hepatitis B guidelines at International Liver Congress

Liz Highleyman | 1 year ago

The European Association for the Study of the Liver (EASL) presented revised clinical practice guid......MORE

Switching to TAF for hepatitis B improves kidney function and bone loss

Liz Highleyman | 1 year ago

People with hepatitis B who switched from the old tenofovir disoproxil fumarate (TDF) to the new te......MORE

A quarter of people with second-line ART treatment failure in Kenya have exhausted current treatment options

Michael Carter | 1 year ago

Affordable third-line antiretrovirals are urgently needed in resource-limited settings, according t......MORE

A quarter of people taking antiretroviral therapy in Kenya have exhausted current treatment options

Michael Carter | 1 year ago

Affordable third-line antiretrovirals are urgently needed in resource-limited settings, according t......MORE

Generic hepatitis C drugs continue to produce high cure rates

Keith Alcorn | 1 year ago

Treatment with generic versions of direct-acting antiviral drugs continues to produce similar cure ......MORE

Switching from Atripla to generic-containing regimens can produce large cost savings

Michael Carter | 1 year ago

Switching from branded Atripla to regimens that include at least one generic drug formulation can a......MORE

AbbVie combination cures 97% of genotype 3 hepatitis C

Keith Alcorn | 1 year ago

AbbVie's pangenotypic direct-acting antiviral combination of two drugs cured 97% of people with ear......MORE

AbbVie combination cures 95% of genotype 3 hepatitis C

Keith Alcorn | 1 year ago

AbbVie's pangenotypic direct-acting antiviral combination of two drugs cured 95% of people with ear......MORE

New AbbVie hepatitis C combination cures 99% of people with cirrhosis

Keith Alcorn | 1 year ago

A new pangenotypic direct-acting antiviral combination developed by AbbVie is highly effective in ......MORE

Direct-acting antivirals for hepatitis C not linked to higher liver cancer risk in most studies

Liz Highleyman | 1 year ago

People with hepatitis C who take treatment with direct-acting antivirals (DAAs) do not appear to ha......MORE

European HCV treatment access survey shows big variations in eligibility

Keith Alcorn | 1 year ago

England, Malta, Slovakia, Hungary and Croatia have the tightest restrictions on who can receive dir......MORE

Curing hepatitis C reduces cardiovascular risk

Keith Alcorn | 1 year ago

Curing hepatitis C reduces the risk of cardiovascular events in people with compensated cirrhosis,......MORE

Monitoring of progress towards 90-90-90 blighted by poor quality reporting

Michael Carter | 1 year ago

Only six countries, representing just 2% of the global HIV burden, have high quality data reporting......MORE

Hepatitis C treatment can be provided successfully at syringe programme sites

Liz Highleyman | 1 year ago

Administering direct-acting antiviral therapy for people who inject drugs at a syringe exchange sit......MORE

Study shows that HIV-positive nursing mothers in London can struggle to obtain and afford formula milk

Michael Carter | 1 year ago

Many HIV-positive nursing mothers in London are struggling to meet the financial costs of formula f......MORE

Black HIV-positive MSM in US still have lower rates of ART use

Michael Carter | 1 year ago

The proportion of newly diagnosed HIV-positive men who have sex with men (MSM) in the United States......MORE

Homeless US military veterans have high rates of HIV, HCV and HBV

Michael Carter | 1 year ago

Homeless veterans in the United States have a significantly higher prevalence of infection with HIV......MORE

Behaviour change interventions in HIV prevention: is there still a place for them?

Gus Cairns | 1 year ago

A meta-analysis of studies of brief interventions to reduce HIV risk behaviour in HIV-negative gay ......MORE

London data show that hepatitis C is passed on during anal sex without a condom

Roger Pebody | 1 year ago

Around one in five HIV-positive gay men who recently acquired hepatitis C report anal sex without a......MORE

PrEP is approved in Scotland

Gus Cairns | 1 year ago

The Scottish Medicines Consortium (SMC) today announced that it had accepted tenofovir disoproxil/e......MORE

Health system navigators didn't improve ART initiation or TB treatment completion rates among people newly diagnosed with HIV in Durban

Michael Carter | 1 year ago

An intervention using health system navigators, phone support and text message reminders did not im......MORE

Suicide accounts for 2% of deaths in people with HIV, twice the rate of the general population

Roger Pebody | 1 year ago

Men living with HIV have an elevated rate of suicide, particularly in the first year after diagnosi......MORE

The large fall in HIV diagnoses in London gay men is real and thanks to combination prevention, not just PrEP

Roger Pebody | 1 year ago

The number of new HIV diagnoses in gay men attending five key London clinics fell substantially dur......MORE

Tracking down patients lost to HIV care: home visits need to be carefully targeted

Keith Alcorn | 1 year ago

Efforts to track patients lost to care are likely to produce very little return on the money and ti......MORE

PrEP should be given to all breastfed babies, researchers say

Gus Cairns | 1 year ago

An international group of researchers involved in the ANRS 12174 randomised controlled trial of pre......MORE

Poppers linked to increased risk of some cancers in older MSM without HIV

Keith Alcorn | 1 year ago

Daily or weekly use of poppers over a number of years is associated with a substantial increase in ......MORE

Poppers linked to increased risk of some cancers in older men who have sex with men without HIV

Keith Alcorn | 1 year ago

Daily or weekly use of poppers over a number of years is associated with a substantial increase in ......MORE

Co-infection with HCV increases cancer risk for people with HIV

Michael Carter | 1 year ago

People with HIV and hepatitis C virus (HCV) co-infection have an increased risk of non-AIDS-definin......MORE

Black gay men still at higher risk of HIV in the UK

Roger Pebody | 1 year ago

Gay and bisexual men of black ethnicity are disproportionately likely to be living with diagnosed H......MORE

Warning of hepatitis A outbreak among men who have sex with men in Europe

Keith Alcorn | 1 year ago

An outbreak of hepatitis A in Europe has affected 287 people in at least 13 countries, with large ......MORE

Investigating late HIV diagnoses as serious incidents may spur change across the health system

Roger Pebody | 1 year ago

Investigating cases of very late HIV diagnosis through the NHS’ serious incident reporting proces......MORE

Nurse-led intervention improves adherence to ART and is cost-effective

Michael Carter | 1 year ago

An antiretroviral therapy (ART) adherence support study conducted in the Netherlands has been haile......MORE

Bone density improves in people who switch from tenofovir DF to tenofovir alafenamide

Liz Highleyman | 1 year ago

After three years, tenofovir alafenamide (TAF) for first-line HIV treatment was better at suppressi......MORE

Scotland reports its lowest number of HIV diagnoses since 2003

Gus Cairns | 1 year ago

A report released on Tuesday by Health Protection Scotland shows that last year saw the lowest numb......MORE

Two-thirds of people with HIV/HCV co-infection in Southeast Asia in need of HCV therapy

Michael Carter | 1 year ago

Almost two-thirds of people with HIV/hepatitis C virus (HCV) co-infection in Asia are in need of HC......MORE

Research helps explain how vedolizumab antibody therapy leads to sustained viral remission

Liz Highleyman | 1 year ago

HIV and its monkey cousin SIV can carry the alpha-4 beta-7 integrin receptor in their outer envelop......MORE

Fewer clinic visits improve retention in HIV care in Zambia

Keith Alcorn | 1 year ago

People with HIV who attended their clinic once every six months were much less likely to miss their......MORE

Harm reduction should address the specific needs of couples who inject drugs

Roger Pebody | 1 year ago

The sharing of drug injecting equipment most often occurs between sexual partners, but the ways in ......MORE

Vietnam will struggle to meet 90-90-90 targets without addressing barriers to HIV care for men who have sex with men

Roger Pebody | 1 year ago

Men who have sex with men in Vietnam risk being left behind as the country strives to achieve UNAID......MORE

Finding men with HIV – and keeping them in treatment

Keith Alcorn | 1 year ago

Specialised services to attract men to HIV testing and treatment may need to adopt several differen......MORE

Linkage to HIV care still challenging for young men, Botswana study finds

Keith Alcorn | 1 year ago

Almost one in five people newly diagnosed with HIV in a study employing active methods to link peop......MORE

Several new candidates in HIV drug pipeline discussed at conference

Liz Highleyman | 1 year ago

This year's Conference on Retroviruses and Opportunistic Infections (CROI 2017), held last month i......MORE

Studies look at brain and cognitive changes in people with HIV as they age

Liz Highleyman | 1 year ago

People with HIV often show persistent signs of cognitive impairment and abnormalities in brain stru......MORE

Early adherence to ART key to long-term virological outcomes

Michael Carter | 1 year ago

Adherence to antiretroviral therapy (ART) in the first few months after starting treatment is cruci......MORE

'Test and treat' study shows second phase is finding more people with HIV and getting them onto treatment

Keith Alcorn | 1 year ago

After a second wave of intensive household testing, a large study of the 'test and treat' strategy ......MORE

Glecaprevir/pibrentasvir for hepatitis C can be safely administered with common antiretrovirals

Liz Highleyman | 1 year ago

AbbVie's investigational glecaprevir/pibrentasvir treatment for hepatitis C is not expected to inte......MORE

Dolutegravir monotherapy fails to maintain HIV viral suppression, but dolutegravir + lamivudine looks good

Liz Highleyman | 1 year ago

Dolutegravir used alone without other antiretrovirals was unable to keep viral load suppressed in s......MORE

DAA therapy cures most people with HIV/HCV co-infection with decompensated cirrhosis or liver transplants

Liz Highleyman | 1 year ago

People with HIV/hepatitis C virus (HCV) co-infection with liver cirrhosis or liver failure, and th......MORE

D:A:D study – long-term use of darunavir/ritonavir modestly increases the risk of cardiovascular disease

Michael Carter | 1 year ago

Long-term use of the protease inhibitor darunavir/ritonavir modestly increases the risk of cardiova......MORE

Simple risk score can identify gay men who may have acute HIV infection

Roger Pebody | 1 year ago

Seven simple questions about symptoms and risk factors identified three-quarters of gay men in Amst......MORE

Researchers report case of bone marrow transplant patient off ART for 288 days without HIV rebound

Liz Highleyman | 1 year ago

An HIV-positive bone marrow transplant recipient at the Mayo Clinic experienced prolonged viral rem......MORE

New HIV capsid inhibitors show high potency and prolonged activity in early studies

Liz Highleyman | 1 year ago

A novel type of antiretroviral drug that interferes with the assembly and disassembly of the HIV ca......MORE

HIV’s milder cousin may be less mild than previously thought

Gus Cairns | 1 year ago

HIV-2’s virulence may have been underestimated and although progression to AIDS  and death in HI......MORE

Integrase inhibitors may increase risk of IRIS in late presenters for HIV treatment

Keith Alcorn | 1 year ago

HIV integrase inhibitors such as dolutegravir and raltegravir may increase the risk of immune recon......MORE

What is safe sex now? Does it include undetectable viral load and PrEP?

Roger Pebody | 1 year ago

Treatment as prevention and PrEP provide new ways to safely avoid HIV, but this poses challenges to......MORE

Are people with HIV and HCV co-infection who are cured of hepatitis C with DAAs at increased risk for liver cancer?

Liz Highleyman | 1 year ago

People with HIV and hepatitis C virus (HCV) co-infection who are successfully treated for hepatitis......MORE

Bacterial vaginosis does not affect efficacy of oral PrEP in women

Gus Cairns | 1 year ago

Research presented at the Conference on Retroviruses and Opportunistic Infections (CROI 2017) found......MORE

STI rates in PrEP users very high, but evidence that PrEP increases them is inconclusive

Gus Cairns | 1 year ago

A study of PrEP users presented at the Conference on Retroviruses and Opportunistic Infections (CRO......MORE

Monoclonal antibodies show promise for HIV-positive people with limited treatment options

Liz Highleyman | 1 year ago

A pair of long-acting monoclonal antibodies that prevent HIV from entering human cells – ibalizum......MORE

No evidence of risk compensation after circumcision in three African cohorts

Roger Pebody | 1 year ago

Three large studies in South Africa, Zimbabwe and Kenya have found no evidence that men who have be......MORE

Accelerated linkage to HIV care improves retention in care by a third

Carole Leach-Lemens | 1 year ago

Close to 60% of adults benefiting from point-of-care CD4 cell count testing at HIV testing sites, a......MORE

Better depression care could improve outcomes for HIV treatment programmes

Roger Pebody | 1 year ago

Improved management of depression and other mental health disorders has the potential to improve th......MORE

Peer navigators improve linkage to HIV care and retention in care in South African study

Carole Leach-Lemens | 1 year ago

Adults recently diagnosed with HIV getting help from peers to address personal barriers to care tog......MORE

Prednisone reduces the risk of developing TB-IRIS after starting antiretroviral treatment

Keith Alcorn | 1 year ago

Prednisone reduces the risk of an immune restoration inflammatory syndrome (IRIS) in people with HI......MORE

Will there be a new wave of HIV in people who inject drugs in the US?

Gus Cairns | 1 year ago

Ever since there was an outbreak of HIV among white, largely rural heroin users in Indiana in 2015,......MORE

Will there be a new wave of HIV in injecting drug users in the US?

Gus Cairns | 1 year ago

Ever since there was an outbreak of HIV among white, largely rural heroin users in Indiana in 2015,......MORE

New NNRTI doravirine shows good efficacy in phase 3 study

Liz Highleyman | 1 year ago

Doravirine, an investigational next-generation non-nucleoside reverse transcriptase inhibitor (NNRT......MORE

Time spent by US HIV patients in care with a transmissible viral load has fallen by three-quarters since 2000

Gus Cairns | 1 year ago

A study by the US Centers for the Disease Control (CDC) presented at the recent Conference on Retro......MORE

Time spent by people in HIV care in US with a transmissible viral load has fallen by three-quarters since 2000

Gus Cairns | 1 year ago

A study by the US Centers for Disease Control and Prevention (CDC) presented at the recent Conferen......MORE

One in five ‘heterosexual’ men in the UK caught their HIV from another man

Gus Cairns | 1 year ago

A genetic analysis of a large database of UK people with HIV in care shows that 18% of men with HIV......MORE

When science, community and political will come together, we can end the epidemic, says New York commissioner

Roger Pebody | 1 year ago

New York City’s strategy to end the AIDS epidemic is firmly rooted in science, was developed in c......MORE

Spanish vaccine induces viral control off ART in nearly 40% of recipients

Gus Cairns | 1 year ago

A so-called ‘HIV Conserv’ vaccine has, for the first time, produced significant prolonged viral......MORE

New hepatitis C infections among HIV-positive gay men drop by half after direct-acting antiviral roll-out in Netherlands

Liz Highleyman | 1 year ago

A little more than a year after the Netherlands instituted a policy allowing unrestricted access to......MORE

Three-drug regimen beats XDR-TB in first trial

Keith Alcorn | 1 year ago

A regimen of three oral drugs given for six months was enough to clear XDR-TB in 29 of the first 31......MORE

How should HIV self-testing services be provided?

Roger Pebody | 1 year ago

Chairing a session on HIV self-testing at the 2017 Conference on Retroviruses and Opportunistic In......MORE

Stopping smoking cuts the risk of some cancers quickly in people with HIV

Keith Alcorn | 1 year ago

Smoking probably contributes far more to the risk of cardiovascular disease in people with HIV than......MORE

Unique case of PrEP failure without drug resistance reported from Amsterdam

Gus Cairns | 1 year ago

HIV pre-exposure prophylaxis (PrEP) appears to be nearly 100% effective if taken consistently so th......MORE

New HIV infections fall in the US, but demographic and geographic disparities persist

Liz Highleyman | 1 year ago

The number of annual new HIV infections in the US fell by 18% overall since 2008, offering evidence......MORE

Isoniazid preventive treatment reduces the risk of death by 37% in people living with HIV

Keith Alcorn | 1 year ago

A six-month course of isoniazid preventive treatment (IPT) at the beginning of the Temprano trial r......MORE

Treatment or watchful waiting for cervical abnormalities in women with HIV?

Carole Leach-Lemens | 1 year ago

Close monitoring of earlier-stage cervical abnormalities (CIN-2) may be preferable to treatment for......MORE

Tenofovir/emtricitabine/efavirenz less likely to cause adverse birth outcomes than other regimens, Botswana study finds

Carole Leach-Lemens | 1 year ago

Infants exposed to an antiretroviral regimen of tenofovir, emtricitabine and efavirenz (Atripla) fr......MORE

Tenofovir/FTC/efavirenz less likely to cause adverse birth outcomes than other regimens, Botswana study finds

Carole Leach-Lemens | 1 year ago

Infants exposed to an antiretroviral (ART) regimen of tenofovir, emtricitabine and efavirenz (TDF/F......MORE

Experimental STI prophylaxis in PrEP users produces big drops in syphilis and chlamydia infections but not in gonorrhoea

Gus Cairns | 1 year ago

Use of the antibiotic doxycycline as on-demand post-exposure prophylaxis by men who have sex with m......MORE

Changes in viral suppression over time reveal disparities in HIV care in the United States

Liz Highleyman | 1 year ago

Sustained viral suppression over the course of a year may be a better measure than the most recent ......MORE

Dual antiretroviral regimen maintains durable HIV suppression after switch

Liz Highleyman | 1 year ago

People who switched from standard antiretroviral therapy to a two-drug regimen of dolutegravir (Tiv......MORE

Infants treated within days of birth can clear HIV reservoir rapidly

Keith Alcorn | 1 year ago

Viral load and viral DNA fall rapidly in infants who begin antiretroviral therapy within days of bi......MORE

Treatment-as-prevention study sees substantial levels of transmitted drug resistance in participants, but no impact on treatment

Gus Cairns | 1 year ago

A study of the prevalence of transmitted drug resistance in participants in the ANRS 12249 trial of......MORE

Point-of-care test improves infant HIV diagnosis rate, treatment starts and retention in care

Keith Alcorn | 1 year ago

Using a point-of-care test to diagnose HIV in infants significantly improved retention in care, spe......MORE

Integrase inhibitor bictegravir matches dolutegravir for first-line HIV treatment

Liz Highleyman | 1 year ago

Bictegravir, an investigational integrase inhibitor from Gilead Sciences, was highly potent, well t......MORE

A benign circle: how a combination of factors has reduced HIV infections in one of the hardest-hit parts of Africa

Gus Cairns | 1 year ago

HIV incidence has started to tumble in one of the best-studied groups of people in Africa, the Conf......MORE

Men from Latin America and central Europe now outnumber sub-Saharan Africans in HIV diagnoses in European migrants

Gus Cairns | 1 year ago

The latest figures from the European Centre for Disease Control (ECDC), presented at the recent HIV......MORE

Across western Europe, migrants from all parts of the world start HIV treatment later

Roger Pebody | 1 year ago

An analysis of over 150,000 people living with HIV in eleven western European countries shows that ......MORE

Living with diagnosed HIV infection for a long time is associated with poor quality of life

Michael Carter | 1 year ago

Longer time living with diagnosed HIV infection is strongly associated with depression, anxiety and......MORE

Sustained reductions in sexual risk behaviour following couples’ HIV testing

Roger Pebody | 1 year ago

A programme of couples’ HIV testing and counselling in Zambia appears to result in durable reduct......MORE

Delays in linkage to care after HIV diagnosis pose the biggest barrier to treatment access

Keith Alcorn | 1 year ago

Following individuals through the cascade of care, from HIV diagnosis to treatment and undetectable......MORE

Women significantly more likely than men to have suboptimal adherence to HIV therapy

Michael Carter | 1 year ago

Women are more likely than men to have poor adherence to combination antiretroviral therapy (cART),......MORE

Legalisation of sex work associated with lower prevalence of HIV in sex workers

Roger Pebody | 1 year ago

Countries that have legalised some aspects of sex work have fewer sex workers living with HIV than ......MORE

High hepatitis C prevalence seen in Amsterdam PrEP study participants

Gus Cairns | 1 year ago

Researchers from the Dutch PrEP demonstration study, AmPrEP, have found an unexpectedly high rate o......MORE

Recreational drug use very common among HIV-positive Londoners admitted for inpatient care

Michael Carter | 1 year ago

Recent recreational drug use is highly prevalent among HIV-positive people admitted to inpatient ca......MORE

Recreational drug use very common among HIV-positive Londoners admitted for in-patient care

Michael Carter | 1 year ago

Recent recreational drug use is highly prevalent among HIV-positive people admitted to in-patient c......MORE

Curing hepatitis C reduces the risk of diabetes & kidney failure in people with HIV/HCV co-infection

Keith Alcorn | 1 year ago

Curing hepatitis C infection substantially reduces the risk of developing type 2 diabetes in people......MORE

Hope overshadowed – the US PrEP Summit

Gus Cairns | 1 year ago

The US National HIV PrEP Summit, which took place in early December in San Francisco, was one of th......MORE

Liver cirrhosis and decompensation still on the rise among people with hepatitis C

Liz Highleyman | 1 year ago

Complications of advanced liver disease including cirrhosis and hepatic decompensation have risen o......MORE

Two-thirds of HIV clinics in the UK don't think there's a current need for specialist services for older HIV-positive patients

Michael Carter | 1 year ago

Two-thirds of HIV clinics in the UK do not think there is a current need for specialist care servic......MORE

Is DAA treatment for hepatitis C reducing the need for liver transplants?

Liz Highleyman | 1 year ago

People successfully treated for hepatitis are less likely to need liver transplants and less likely......MORE

No new HIV infections in Northern California Kaiser PrEP programme, but STI rates rising

Liz Highleyman | 1 year ago

No new HIV infections have been seen among nearly 1000 people who started Truvada for pre-exposure ......MORE

Starting treatment quickly after diagnosis is not harmful for adolescents, Zimbabwe study finds

Keith Alcorn | 1 year ago

A lack of lengthy preparation before starting HIV treatment does not result in an increased risk of......MORE

High prevalence of low testosterone among younger and middle-aged ART-treated men in France

Michael Carter | 1 year ago

Around one in six young and middle-aged HIV-positive men doing well on antiretroviral therapy (ART)......MORE

Regular small incentives can improve adherence to ART

Michael Carter | 1 year ago

The provision of regular low-value economic incentives can improve adherence to antiretroviral ther......MORE

What are the key steps to effective delivery of PrEP care?

Roger Pebody | 1 year ago

Providing pre-exposure prophylaxis (PrEP) to people who need it entails at least nine key steps, wh......MORE

Many older people living with HIV in the UK worried about poverty, loneliness and social care

Roger Pebody | 1 year ago

People over the age of 50 now represent one third of all people living with HIV, but the social car......MORE

Vitamin D deficiency reduces statin potency, increases risk of muscle pain in people with HIV

Keith Alcorn | 1 year ago

People living with HIV who take statins are less likely to experience cholesterol reductions and mo......MORE

Tenofovir alafenamide approved for hepatitis B in Europe

Liz Highleyman | 1 year ago

The European Commission this week granted marketing authorisation for tenofovir alafenamide, to be ......MORE

ART-treated patients in UK have an accurate understanding of their viral load

Michael Carter | 1 year ago

The vast majority of antiretroviral (ART)-treated patients in the UK have an accurate knowledge of ......MORE

People taking ART in the UK have an accurate understanding of their viral load

Michael Carter | 1 year ago

The vast majority of people taking antiretroviral therapy (ART) in the UK have an accurate knowledg......MORE

Implants and injectables: PrEP in the future

Keith Alcorn | 1 year ago

Last month’s announcement that the Bill and Melinda Gates Foundation will give up to $140 million......MORE

Risk of pregnancy loss among smokers much higher for women with HIV

Michael Carter | 1 year ago

Smoking “dramatically” increases the risk of pregnancy loss – miscarriage or stillbirth – i......MORE

Risk score accurately predicts which pregnant and postpartum women would benefit most from PrEP

Michael Carter | 1 year ago

A risk score based on routine assessments carried out during antenatal care in resource-limited set......MORE

Nearly two-thirds of European HIV cases are now in Russia

Gus Cairns | 1 year ago

The annual number of new cases of HIV increased by at least 8% in 2015 in the whole of the World He......MORE

Scaling up adult male circumcision calculated to have HIV prevention benefits additional to those seen with 90-90-90 treatment target

Michael Carter | 1 year ago

Scale-up of voluntary medical male circumcision (VMMC) in countries with a high HIV prevalence has ......MORE

Viral load rebounds in a third of women who start HIV therapy during pregnancy or postpartum, South African study shows

Michael Carter | 1 year ago

Approximately one-third of HIV-positive women who attain viral suppression after starting antiretro......MORE

Viral load testing capacity still weak in sub-Saharan Africa, 7-country study finds

Keith Alcorn | 1 year ago

Viral load testing capacity is still weak in some of the countries with the highest burden of HIV i......MORE

People with HIV/HCV co-infection at increased risk of kidney disease and bone disorders

Michael Carter | 1 year ago

Hepatitis C virus (HCV) infection in people with HIV co-infection is associated with an increased r......MORE

Virologic failure detected in a quarter of ART-treated children in Tanzania

Michael Carter | 1 year ago

A quarter of children and adolescents in Tanzania taking antiretroviral therapy (ART) have major re......MORE

The UK’s largest sexual health clinic saw a 40 percent drop in new HIV infections this year

Gus Cairns | 1 year ago

The clinic at 56 Dean Street in Soho, central London, the largest sexual health clinic in the UK, s......MORE

In the era of universal treatment, what are HIV clinical guidelines for?

Gus Cairns | 1 year ago

The purpose and structure of clinical HIV guidelines may have to change radically now that universa......MORE

African Americans taking ART have high incidence of illness associated with risk of cardiovascular disease

Michael Carter | 1 year ago

Black HIV-positive men and women receiving antiretroviral therapy (ART) have especially high rates ......MORE

Co-morbidities are common and rising among people with HIV in the US

Liz Highleyman | 1 year ago

People living with HIV are increasingly experiencing a range of non-AIDS-related comorbidities as t......MORE

High prevalence of resistance to zidovudine among people in sub-Saharan Africa experiencing virological failure with tenofovir-containing ART

Michael Carter | 1 year ago

A significant proportion of people with virological failure after treatment with tenofovir-containi......MORE

Migration and age differences between male and female partners fuelling the HIV epidemic in South Africa

Roger Pebody | 1 year ago

Analyses from two large household surveys in KwaZulu-Natal, South Africa shed new light on the dyna......MORE

Multiple motivations for ‘transactional sex’ need to be taken into account when planning interventions for African women

Roger Pebody | 1 year ago

Many HIV prevention strategies identify ‘transactional sex’ as a practice that contributes to y......MORE

Malawi, Zambia and Zimbabwe making strong progress towards the 90-90-90 goals

Keith Alcorn | 1 year ago

Malawi, Zambia and Zimbabwe are making strong progress towards achieving the treatment and viral su......MORE

Almost half of MSM with HIV/HCV co-infection have HCV in their rectal fluid

Michael Carter | 1 year ago

Almost half of HIV-positive men who have sex with men (MSM) who have co-infection with hepatitis C ......MORE

Sofosbuvir-based therapy achieves excellent SVR12 rates among people who inject drugs in the Ukraine

Michael Carter | 1 year ago

People who inject drugs (PWID) can have an excellent response to sofosbuvir-based therapy for hepat......MORE

Sofosbuvir-based therapy achieves excellent SVR12 rates among people who inject drugs in Ukraine

Michael Carter | 1 year ago

People who inject drugs (PWID) can have an excellent response to sofosbuvir-based therapy for hepat......MORE

United States: Syringe service use up, but a third of people who inject drugs still share needles

Liz Highleyman | 1 year ago

Use of syringe exchange and distribution services has increased substantially over the past decade ......MORE

Electronic monitoring of antiretroviral adherence in "real time" boosts pill taking and need for intensive adherence support

Michael Carter | 1 year ago

Electronic monitoring of antiretroviral adherence in “real time” significantly increases the pr......MORE

Electronic monitoring of antiretroviral adherence in "real-time" boosts pill taking and need for intensive adherence support

Michael Carter | 1 year ago

Electronic monitoring of antiretroviral adherence in “real time” significantly increases the pr......MORE

Hepatitis C virus infection is rising among gay and bisexual men in San Diego

Liz Highleyman | 1 year ago

The prevalence of hepatitis C virus (HCV) infection among HIV-positive men who have sex with men in......MORE

NHS England announces major new PrEP trial for 2017

Gus Cairns | 1 year ago

NHS England, in collaboration with Public Health England, has announced in a press release today th......MORE

Survey finds good knowledge of PrEP in Europe and a considerable amount of unsupported informal PrEP use

Gus Cairns | 1 year ago

A large survey of knowledge and use of pre-exposure prophylaxis (PrEP) in Europe released its preli......MORE

There may be fewer people living with undiagnosed HIV in the UK than previously thought

Roger Pebody | 1 year ago

Public Health England’s estimate of the number of people who have HIV without being aware of it h......MORE

CDC releases new data on HIV diagnosis and prevalence in the United States

Liz Highleyman | 1 year ago

In advance of World AIDS Day the US Centers for Disease Control and Prevention (CDC) released its l......MORE

Ending the HIV epidemic faces daunting barriers, former WHO HIV chief warns

Gus Cairns | 1 year ago

The difficulty of bringing the HIV epidemic “down to zero” should not be underestimated, Kevin ......MORE

World Health Organization urges scale-up of HIV self-testing

Roger Pebody | 1 year ago

HIV self-testing (sometimes called ‘home testing’) should be offered as an additional approach ......MORE

Health agencies should challenge the idea that most gay men use drugs

Roger Pebody | 1 year ago

Drug use generally and chemsex more specifically are perceived to be common and normalised behaviou......MORE

Sofosbuvir/ledipasvir is effective for people with HIV/HCV co-infection in real-world clinical practice

Liz Highleyman | 1 year ago

The sofosbuvir/ledipasvir (Harvoni) co-formulation used in real-world clinical practice produced go......MORE

Sofosbuvir/ledipasvir is effective for HIV/HCV co-infected people in real-world clinical practice

Liz Highleyman | 1 year ago

The sofosbuvir/ledipasvir (Harvoni) coformulation used in real-world clinical practice produced goo......MORE

Grazoprevir triple regimen demonstrates high cure rates, even for hard-to-treat people

Liz Highleyman | 1 year ago

A new three-drug co-formulation containing Merck's grazoprevir plus the investigational agents MK-3......MORE

People with HIV/HCV co-infection see good cure rates in real-world practice in Madrid

Liz Highleyman | 1 year ago

More than 90% of HIV-positive people treated with direct-acting antivirals for hepatitis C – incl......MORE

Chemsex and slamming “suffused with romantic, emotional and communal attachments”

Roger Pebody | 1 year ago

While gay men’s use of drugs in sexual contexts is often portrayed as deviant, extreme and unconn......MORE

8-week triple DAA combo cures most people with genotype 1-6 hepatitis C

Liz Highleyman | 1 year ago

A three-drug regimen of sofosbuvir, velpatasvir and voxilaprevir taken for 8 weeks demonstrated an ......MORE

Birth cohort screening and linkage to care for HCV treatment still weak in United States

Keith Alcorn | 1 year ago

Grave weaknesses in hepatitis C screening and linkage to care are still widespread in the United St......MORE

AbbVie pangenotypic combination cures 98% or above across genotypes

Keith Alcorn | 1 year ago

AbbVie’s combination of glecaprevir and pibrentasvir cured at least 98% of people with hepatitis ......MORE

AbbVie pangenotypic combination cures almost all hard-to-treat people with HCV genotype 3

Keith Alcorn | 1 year ago

AbbVie’s pangenotypic combination of glecaprevir and pibrentasvir cured almost all of the hardest......MORE

US Veterans Affairs and Australia show potential for rapid elimination of hepatitis C

Keith Alcorn | 2 years ago

If sufficient money is available to pay for direct-acting antivirals (DAAs), the US Veterans Affair......MORE

Tenofovir alafenamide approved for hepatitis B, works well with less effect on bones

Liz Highleyman | 2 years ago

Tenofovir alafenamide (TAF), a new lower-dose pro-drug, matches the older tenofovir disoproxil fuma......MORE

Self-sampling for HIV testing popular with gay men who have not recently tested, but less uptake by African people

Roger Pebody | 2 years ago

Three quarters of those using England’s free self-sampling service are men who have sex with men,......MORE

Long term decline in consistent condom use among Australian gay men

Roger Pebody | 2 years ago

Data from the last ten years of the Australian Gay Community Periodic Surveys shows a steady declin......MORE

Grazoprevir/elbasvir + sofosbuvir highly effective for hard-to-treat genotype 3 hepatitis C patients

Liz Highleyman | 2 years ago

A triple regimen of grazoprevir/elbasvir (Zepatier) plus sofosbuvir (Sovaldi) without ribavirin cur......MORE

Liver cancer risk reduced after hepatitis C treatment, but vigilance needed for aggressive cancers in months after treatment

Keith Alcorn | 2 years ago

People who are cured of hepatitis C after a course of direct-acting antiviral treatment do not hav......MORE

Real-world responses to HCV treatment among US veterans match best clinical trial results

Keith Alcorn | 2 years ago

Direct-acting antiviral treatment is curing people of hepatitis C infection in clinics at similar r......MORE

The ‘long tail’ problem: injected-PrEP trial will be extended due to persistence of drug in companion study

Gus Cairns | 2 years ago

A study presented at last month’s HIV Research for Prevention (HIVR4P) conference in Chicago show......MORE

The ‘long tail’ problem: forthcoming injected-PrEP efficacy trial delayed due to persistence of drug in some volunteers

Gus Cairns | 2 years ago

A study presented at last month’s HIV Research for Prevention (HIVR4P) conference in Chicago show......MORE

NHS England loses appeal – it must consider providing PrEP

Roger Pebody | 2 years ago

At the Court of Appeal in London this morning, three judges confirmed that NHS England is responsib......MORE

Tenofovir alafenamide works well and improves kidney and bone markers in older people living with HIV

Liz Highleyman | 2 years ago

A co-formulation of tenofovir alafenamide (TAF) plus emtricitabine, used with a third antiretrovir......MORE

Omega-3 fatty acids may reduce triglycerides and improve inflammation in people with HIV

Liz Highleyman | 2 years ago

Long-term use of omega-3 fatty acid supplements was associated with reduced levels of triglycerides......MORE

Smoking more harmful than HIV for people taking effective treatment, US study suggests

Keith Alcorn | 2 years ago

Smoking has the potential to shorten the life of a person taking HIV treatment by an average of six......MORE

Dolutegravir regimen highly effective in clinical trial for women

Liz Highleyman | 2 years ago

A once-daily regimen containing the potent HIV integrase inhibitor dolutegravir worked better than......MORE

Ibalizumab monoclonal antibody looks promising for people with drug-resistant HIV

Liz Highleyman | 2 years ago

Ibalizumab, an experimental monoclonal antibody with a unique mechanism of action, demonstrated goo......MORE

Men with HIV and men on PrEP in Boston see large increase in sexually transmitted infections

Liz Highleyman | 2 years ago

Rates of gonorrhoea, syphilis and chlamydia have risen steeply at Fenway Health in Boston since 201......MORE

Four days on, three days off HIV treatment controls viral load in French pilot study

Keith Alcorn | 2 years ago

An experimental `four days on, three days off` antiretroviral regimen kept viral load fully suppre......MORE

Do people living with HIV who have an undetectable viral load need to wear condoms?

Liz Highleyman | 2 years ago

In the face of extensive research showing that people living with HIV who are on antiretroviral the......MORE

Electronic health records can help select candidates for HIV PrEP

Liz Highleyman | 2 years ago

A machine learning algorithm used to analyse electronic health records (EHRs) identified high-risk ......MORE

Darunavir/ritonavir & lamivudine matches triple-drug therapy

Keith Alcorn | 2 years ago

Simplifying antiretroviral therapy to a two-drug combination of lamivudine plus the protease inhibi......MORE

Only a small proportion of gay men with HIV receive anal cancer screening

Liz Highleyman | 2 years ago

In the absence of national screening guidelines, only 11% of HIV-positive gay and bisexual men in t......MORE

New long-acting fusion inhibitor albuvirtide plus boosted protease inibitor matches standard triple-drug therapy

Keith Alcorn | 2 years ago

A new fusion inhibitor, albuvirtide, under development in China, combined with a boosted protease i......MORE

Generic hepatitis C drugs purchased online achieve high cure rates

Keith Alcorn | 2 years ago

Use of generic versions of direct-acting antivirals resulted in very high cure rates for people who......MORE

Tests of online PrEP purchases by London clinic find no fakes, and adequate drug levels

Gus Cairns | 2 years ago

A sexual health clinic in central London that offered to test drug levels in users of tenofovir/emt......MORE

The benefit of treatment has outweighed the clinical impact of lipodystrophy, conference hears

Gus Cairns | 2 years ago

The 2016 Glasgow HIV Conference heard today that over a 20-year period, people who suffered lipodys......MORE

French study reveals the growing complexity of medical needs as people with HIV age

Keith Alcorn | 2 years ago

The complexity of the needs of people living with HIV will continue to increase as the population a......MORE

Dolutegravir and central nervous system side-effects: abacavir, older age increase the risk

Keith Alcorn | 2 years ago

Insomnia, dizziness, headache and other central nervous system side effects are occurring more freq......MORE

Some of the Americans who need PrEP the most face the greatest barriers to getting it

Roger Pebody | 2 years ago

The personal values and moral judgements of healthcare providers are likely to interfere with the a......MORE

Two-drug HIV therapy just as effective as three-drug therapy

Keith Alcorn | 2 years ago

Simplification of an antiretroviral treatment to a boosted protease inhibitor and the nucleoside an......MORE

As PrEP knowledge increases in San Francisco, 12,500 people now thought to be on PrEP

Liz Highleyman | 2 years ago

Knowledge about and use of HIV pre-exposure prophylaxis (PrEP) has greatly increased over the past ......MORE

New $90-$90-$90 target needed for global viral hepatitis, HIV and TB treatment

Keith Alcorn | 2 years ago

The costs of making drugs to treat viral hepatitis, HIV and TB are now so low that each disease cou......MORE

New HIV prevention products will need marketing and effective health services to reach the people who need them

Roger Pebody | 2 years ago

There is a naivety among many HIV prevention researchers and advocates about the steps needed to in......MORE

Huge diversity in current HIV vaccine research, Research for Prevention conference hears

Gus Cairns | 2 years ago

The HIV vaccine research field is currently going through probably its most fertile and diverse per......MORE

New microbicide enema achieves high levels of drug in rectal tissues in monkeys

Gus Cairns | 2 years ago

Rectal microbicides that protect against HIV transmission via anal sex are a bigger technical chall......MORE

Rings, films or inserts? Researchers need to develop prevention products that make sense in women’s lives

Roger Pebody | 2 years ago

“We need to think outside of the box,” Sharon Hillier of the Microbicide Trials Network told th......MORE

Vaginal and rectal bacteria may have a big influence on HIV transmission and microbicide efficacy

Gus Cairns | 2 years ago

A number of presentations at the 2016 HIV Research for Prevention Conference (HIVR4P) in Chicago lo......MORE

Controlling the HIV epidemic: ambitious funding, expanded workforce, innovations and micro-focus needed

Keith Alcorn | 2 years ago

Advocates who seek to end AIDS by 2030 should be ready to call on Hillary Clinton to massively incr......MORE

Policy makers’ inaction is leading people to take PrEP ‘in the wild’

Roger Pebody | 2 years ago

An increasing number of gay men and others at risk of HIV are seeking to protect their health with ......MORE

Anal sex may transmit four in ten HIV infections in US women at high risk

Gus Cairns | 2 years ago

A study presented at the 2016 HIV Research for Prevention (HIVR4P) Conference in Chicago, USA sugge......MORE

Second case report of PrEP failure due to drug-resistant virus

Roger Pebody | 2 years ago

A PrEP user in New York City has become HIV positive with virus that is resistant to Truvada and ot......MORE

Mental health disorders common among people with HIV in British Columbia

Michael Carter | 2 years ago

Over 50% of people with HIV, many from disenfranchised groups, in British Columbia, Canada, are liv......MORE

Crohn’s disease drug produces long-lasting viral undetectability and T-cell restoration off treatment in monkeys

Gus Cairns | 2 years ago

In a promising experiment in rhesus macaque monkeys, scientists from Emory University in Atlanta ha......MORE

Doctors in Netherlands observe higher than expected dolutegravir treatment discontinuation rate

Michael Carter | 2 years ago

Almost one in seven people in a Dutch clinic population stopped treatment with the HIV integrase in......MORE

Less than 100% adherence to HIV therapy, even with viral suppression, can lead to more inflammation and immune activation

Michael Carter | 2 years ago

Research involving men taking antiretroviral therapy, all with an undetectable viral load, has show......MORE

Educational attainment associated with health outcomes after starting HIV therapy

Michael Carter | 2 years ago

People with HIV who have lower educational attainment have poorer outcomes after starting combinati......MORE

No evidence that contaminated nelfinavir led to increased risk of birth abnormalities or cancer

Michael Carter | 2 years ago

HIV-negative infants potentially exposed in utero to doses of the HIV protease inhibitor nelfinavir......MORE

Promising trends continue in UK diagnosis and treatment rates

Gus Cairns | 2 years ago

A ‘mini report’ of the latest figures on HIV diagnoses, late diagnosis, and treatment uptake in......MORE

Hepatitis B testing should be done before hepatitis C treatment due to risk of HBV reactivation

Liz Highleyman | 2 years ago

People considering direct-acting antiviral (DAA) therapy for hepatitis C should first be tested for......MORE

Gay men with overlapping partnerships are more likely to be recently and locally infected

Gus Cairns | 2 years ago

A study analysing transmission patterns between gay men in a cohort of patients on San Diego, Calif......MORE

100% cure rate for people with HCV genotype 1 treated with AL-335, odalasvir and simeprevir for 6 or 8 weeks

Liz Highleyman | 2 years ago

A triple regimen containing two experimental hepatitis C drugs – AL-335 and odalasvir – plus si......MORE

Young people say that sex and relationships education in schools is negative and out of touch

Roger Pebody | 2 years ago

A review of 55 separate studies of sex and relationships education (SRE) in schools shows that youn......MORE

Media reports of a British HIV cure 'breakthrough' are premature

Keith Alcorn | 2 years ago

The Sunday Times yesterday reported that HIV had become undetectable in the blood of one man takin......MORE

Hepatitis C infection and reinfection among men who have sex with men need higher priority, US and European studies show

Liz Highleyman | 2 years ago

Public health officials in Michigan have identified a cluster of more than 20 cases of apparently s......MORE

Syphilis rates rising among gay men in US, CDC data show

Liz Highleyman | 2 years ago

New state-level data reveal that syphilis cases continue to rise among gay and bisexual men in the ......MORE

Risk of reinfection is a concern after successful hepatitis C treatment

Liz Highleyman | 2 years ago

People on opiate agonist substitution therapy can be successfully treated with grazoprevir/elbasvir......MORE

Dutch model finds PrEP for high-risk gay men is cost-effective at current prices and cost-saving at generic prices

Gus Cairns | 2 years ago

A mathematical modelling study based on the HIV epidemic in the Netherlands has found that daily Pr......MORE

EASL issues new hepatitis C treatment recommendations for all genotypes

Liz Highleyman | 2 years ago

The European Association for the Study of the Liver (EASL) released its latest recommendations on t......MORE

Structural inequalities create vulnerability to HIV for black gay men in New York

Roger Pebody | 2 years ago

The sexual relationships of many African American men who have sex with men are largely shaped by e......MORE

Early infant HIV testing at birth and at 6 weeks of age will save lives, extend life expectancy and is cost-effective for South Africa, study finds

Michael Carter | 2 years ago

Early infant HIV diagnosis in South Africa will save lives, extend life expectancy and be cost-effe......MORE

Spanish study gives reassurance: small HIV blips do not predict treatment failure

Michael Carter | 2 years ago

A very low viral load (20-49 copies/ml) during HIV therapy does not increase the risk of the subseq......MORE

HCV treatment is effective and may work as prevention for people who inject drugs

Liz Highleyman | 2 years ago

Hepatitis C treatment for people who inject drugs is as safe and effective as it is for non-drug-us......MORE

New York clinic outlines how to improve uptake of PrEP by transgender people

Roger Pebody | 2 years ago

Dedicated efforts are needed to engage transgender men and women with clinical services and to enco......MORE

Ugandan experience shows TB detection can be successfully incorporated into community HIV testing campaigns

Michael Carter | 2 years ago

Community health campaigns provide an opportunity to detect previously undiagnosed cases of tubercu......MORE

Where would gay men prefer to take their next HIV test?

Roger Pebody | 2 years ago

Among English gay men who have never previously taken a test for HIV, self-testing and self-samplin......MORE

Hepatitis C vaccine development shows progress but scientific barriers remain

Liz Highleyman | 2 years ago

An effective vaccine may be necessary to eliminate hepatitis C virus (HCV) but development has been......MORE

Sweden the first country to achieve UNAIDS/WHO 90-90-90 target

Michael Carter | 2 years ago

Sweden has become the first country to achieve the UNAIDS/WHO 90-90-90 target, research published i......MORE

Managing non-communicable diseases among people living with HIV

Theo Smart | 2 years ago

Non-communicable diseases - including cardiovascular diseases, diabetes, cancers, and other illnes......MORE

Delays in updating HIV treatment guidelines in Africa blocking early treatment for millions

Keith Alcorn | 2 years ago

Delays in adopting the World Health Organization’s 2015 recommendation of HIV treatment for all t......MORE

Effective antiviral treatment reduces fatigue in people with chronic hepatitis C

Liz Highleyman | 2 years ago

Fatigue – a common symptom among people living with hepatitis C virus (HCV) infection – is asso......MORE

INHSU 2016 opens with focus on hepatitis C prevention and treatment for people who inject drugs

Liz Highleyman | 2 years ago

The 5th International Symposium on Hepatitis Care in Substance Users (INHSU 2016) got underway yest......MORE

London gay men anticipate some pros and cons of different PrEP methods – but optimal efficacy is key to acceptability

Roger Pebody | 2 years ago

When presented with a range of possible HIV prevention technologies – a daily pill, pills before ......MORE

Acceptability of PrEP for London gay men affected by perception of risk, sexual partners’ attitudes and the stigmatisation of sex

Roger Pebody | 2 years ago

PrEP is broadly acceptable to London gay men who are at risk of acquiring HIV, with many men seeing......MORE

Life expectancy of patients starting HIV therapy differs sharply between high and middle/low income countries

Michael Carter | 2 years ago

There are significant disparities in the life expectancy of HIV-positive patients starting combinat......MORE

Life expectancy of people starting HIV therapy differs sharply between high- and middle/low-income countries

Michael Carter | 2 years ago

There are significant disparities in the life expectancy of HIV-positive people starting combinatio......MORE

HIV-positive gay and bisexual men have increased risk of hospitalisation with anxiety and mood disorders, a risk factor for later mortality

Michael Carter | 2 years ago

HIV-positive gay and bisexual men are almost ten times more likely to be hospitalised because of mo......MORE

Statins reduce risk of progression to cirrhosis in people with HIV/HCV co-infection

Michael Carter | 2 years ago

Treatment with statins decreases the risk of progression to liver cirrhosis in people with HIV and ......MORE

Statins reduce risk of progression to cirrhosis in HIV/HCV-co-infected people

Michael Carter | 2 years ago

Treatment with statins decreases the risk of progression to liver cirrhosis in people co-infected w......MORE

San Francisco reports new low in HIV infections and faster treatment, but disparities remain

Liz Highleyman | 2 years ago

On September 1 the San Francisco Department of Public Health released its HIV Epidemiology Annual R......MORE

Improvements in HIV treatment and care have had no impact on rates of endstage liver disease among HIV-positive people with viral hepatitis

Michael Carter | 2 years ago

Incidence of endstage liver disease (ESLD) among HIV-positive people with viral hepatitis changed l......MORE

Improvements in HIV treatment and care have had no impact on rates of endstage liver disease among HIV-positive patients with viral hepatitis

Michael Carter | 2 years ago

Incidence of endstage liver disease (ESLD) among HIV-positive patients with viral hepatitis changed......MORE

Vaginal ring for HIV prevention effective and acceptable

Roger Pebody | 2 years ago

An updated adherence analysis from the ASPIRE study indicates that consistent users of a vaginal ri......MORE

Study looks at use of PrEP during pregnancy and breastfeeding

Liz Highleyman | 2 years ago

Women in San Francisco and the New York City frequently chose to use Truvada for pre-exposure prop......MORE

Realism needed about the benefits and risks of taking part in HIV cure studies

Roger Pebody | 2 years ago

A significant proportion of people living with HIV would be willing to take part in a study towards......MORE

Depression increases risk of heart attack for adults with HIV

Michael Carter | 2 years ago

Major depression is associated with an increased risk of heart attack for middle-aged HIV-positive ......MORE

Elevated lipids associated with cognitive decline in middle-aged HIV-positive men doing well on ART

Michael Carter | 2 years ago

Elevated cholesterol and a gene associated with Alzheimer’s risk in the general population are bo......MORE

Elevated lipids associated with cognitive decline in middle aged HIV-positive men doing well on ART

Michael Carter | 2 years ago

Elevated cholesterol and a gene associated with Alzheimer’s risk in the general population are bo......MORE

US PrEP study achieves high levels of engagement and adherence among black men who have sex with men

Gus Cairns | 2 years ago

What was described at the AIDS2016 conference as “The first PrEP trial devised and run by four bl......MORE

Many people in the US with chronic hepatitis B not being properly monitored

Michael Carter | 2 years ago

Many people with chronic hepatitis B (CHB) virus infection have infrequent medical monitoring, acco......MORE

Neglect of infectious diseases in prisons highlighted at AIDS 2016

Theo Smart | 2 years ago

“Prisoners are among the most neglected of the key populations; they bear higher burdens of HIV, ......MORE

HIV not a risk factor for fibrosis progression in people with hepatitis C

Michael Carter | 2 years ago

HIV co-infection is not associated with accelerated progression of liver fibrosis in people with he......MORE

New WHO algorithm to prevent TB deaths in very ill people with HIV

Theo Smart | 2 years ago

The World Health Organization (WHO) has released a new diagnostic algorithm in order to reduce the ......MORE

German medicines watchdog rejects ‘new tenofovir’ pill

Gus Cairns | 2 years ago

The German health technology assessment agency IQWiG has announced that it finds no advantage in De......MORE

How can clinical services engage men who have sex with men in Africa?

Roger Pebody | 2 years ago

Men who have sex with men living in African countries have an extremely high burden of HIV, Stefan ......MORE

Poor kidney function associated with increased cardiovascular risk for people with HIV

Michael Carter | 2 years ago

Renal impairment is associated with an increased risk of cardiovascular disease (CVD) in HIV-positi......MORE

Most contraceptives not linked to HIV infection, but Depo-Provera may raise risk

Liz Highleyman | 2 years ago

Birth control pills and some types of injectable and implanted contraceptives were not associated w......MORE

Ongoing hepatitis B virus replication associated with higher mortality for people with HIV

Liz Highleyman | 2 years ago

People with HIV and hepatitis B virus (HBV) co-infection have more than double the risk of death if......MORE

Vaginal bacteria increase HIV susceptibility and may reduce PrEP effectiveness

Liz Highleyman | 2 years ago

Overgrowth of a certain species of vaginal bacteria was associated with a 13-fold higher likelihood......MORE

Most patients taking second-line ART in sub-Saharan Africa achieve viral suppression but there's a need for third-line treatment options

Michael Carter | 2 years ago

Approximately 85% of patients switched to protease inhibitor-based second-line antiretroviral (ART)......MORE

Most people taking second-line ART in sub-Saharan Africa achieve viral suppression but there's a need for third-line treatment options

Michael Carter | 2 years ago

Approximately 85% of people switched to protease inhibitor-based second-line antiretroviral (ART) i......MORE

No new HIV infections seen in San Francisco's Strut PrEP programme

Liz Highleyman | 2 years ago

A community-based sexual health clinic in San Francisco has offered nurse-led pre-exposure prophyla......MORE

Efavirenz appears to be associated with elevated suicide risk in START trial

Liz Highleyman | 2 years ago

Participants in the START treatment-timing trial who took antiretroviral regimens containing efavir......MORE

A detectable CMV viral load could signal a high risk of mortality in older individuals hospitalised with HIV-associated TB

Theo Smart | 2 years ago

A study conducted in a cohort of hospitalised HIV-associated TB coinfected adults from Khayelitsha......MORE

People shifting from paediatric to adult HIV care have a high risk of ART failure

Michael Carter | 2 years ago

HIV-positive adolescents and young adults are especially likely to experience the virological failu......MORE

Patients shifting from paediatric to adult HIV care have a high risk of ART failure

Michael Carter | 2 years ago

HIV-positive adolescents and young adults are especially likely to experience the virological failu......MORE

Package of prophylaxis against infections reduces the risk of death for people starting HIV treatment very late

Keith Alcorn | 2 years ago

A package of enhanced prophylaxis against infections significantly reduced the risk of death in adu......MORE

Ending AIDS by 2030 a distant prospect, global HIV incidence, prevalence, treatment coverage and mortality figures suggest

Michael Carter | 2 years ago

Remarkable progress has been made towards curbing the global HIV epidemic, but there is little chan......MORE

AbbVie 3D and 2D hepatitis C combos work well for people with HIV and HCV co-infection

Liz Highleyman | 2 years ago

AbbVie's paritaprevir-based 3D regimen for hepatitis C virus (HCV) genotype 1 and 2D regimen for ge......MORE

START analysis looks at who benefits most from immediate HIV treatment

Liz Highleyman | 2 years ago

Starting antiretroviral therapy (ART) soon after HIV diagnosis led to better outcomes than delayed ......MORE

High Court rules NHS England is responsible for funding PrEP

Keith Alcorn | 2 years ago

A judicial review in the High Court has ruled that NHS England is responsible for funding pre-expos......MORE

Training community health workers to perform intensified TB case finding associated with a surge in TB diagnoses in a rural Malawi study

Theo Smart | 2 years ago

Intensified TB case finding (TB ICF) by community health workers was associated with a dramatic (20......MORE

Searching for the next ‘Berlin patient’: doctors document bone-marrow recipients with HIV

Gus Cairns | 2 years ago

The ‘Berlin patient’, Timothy Ray Brown, has now survived seven years off antiretroviral therap......MORE

PrEP rollout recipients in France top 1000: full trial results report 97% effectiveness

Gus Cairns | 2 years ago

Up to July 2016, 1077 people, 96.4% of them gay men, have started HIV pre-exposure prophylaxis (PrE......MORE

PrEP rollout recipients in France top 1,000: full trial results report 97% effectiveness

Gus Cairns | 2 years ago

Up to July 2016, 1077 people, 96.4% of them gay men, have started HIV pre-exposure prophylaxis (PrE......MORE

Stigma persists in the undetectable era

Roger Pebody | 2 years ago

In an era of widespread HIV treatment and undetectable viral load, stigma remains a persistent feat......MORE

Reducing clinic visits can support retention in HIV care, African studies show

Keith Alcorn | 2 years ago

Interventions which reduce the need for people to attend clinics are proving highly successful in r......MORE

High-dose rifampicin for TB treatment regimen may improve survival in people with low CD4 cell counts

Theo Smart | 2 years ago

More aggressive TB treatment using high dose of rifampicin, in addition to ARV treatment, could red......MORE

Early HIV treatment: mothers say they need time to think

Carole Leach-Lemens | 2 years ago

Findings from the first randomised controlled trial to date evaluating postpartum antiretroviral th......MORE

Mapping local HIV epidemics can help target resources to areas with the greatest need

Roger Pebody | 2 years ago

Global health agencies have recently put a new emphasis on geography. UNAIDS have called for progra......MORE

Women with HIV have higher risk of loss to follow-up and death after delivery

Carole Leach-Lemens | 2 years ago

Despite the widespread implementation of Option B+ (lifelong antiretroviral therapy (ART) for pregn......MORE

Phone and home visit follow-up and appointment trackers improve retention in HIV care for pregnant women and new mothers

Carole Leach-Lemens | 2 years ago

Phone and home visit follow-ups, improved use of appointment books to track attendance and patient-......MORE

Once-daily raltegravir works as well as twice-daily for initial HIV treatment

Liz Highleyman | 2 years ago

A new formulation of the integrase inhibitor raltegravir (Isentress) taken once daily suppressed H......MORE

Bone loss partially recovers after stopping PrEP, twice-yearly kidney monitoring is enough for most

Liz Highleyman | 2 years ago

Young adults taking Truvada for pre-exposure prophylaxis (PrEP) experienced a modest decrease in bo......MORE

Dolutegravir plus lamivudine dual therapy works well as initial HIV treatment

Liz Highleyman | 2 years ago

A two-drug regimen of dolutegravir and the well-tolerated NRTI lamivudine led to sustained viral su......MORE

Access to HIV home tests doubles the frequency of HIV testing in Australian gay men

Roger Pebody | 2 years ago

A randomised trial conducted with Australian gay men has shown that easy access to self-testing kit......MORE

'Test and treat': large study fails to show an impact on new HIV infections

Roger Pebody | 2 years ago

The first major research study of ‘test and treat’ as a public health intervention to report it......MORE

Earlier HIV treatment is not over-burdening health services

Keith Alcorn | 2 years ago

Earlier treatment initiation is not overwhelming rural health services in South Africa, but changes......MORE

Long-acting injectable drugs work well for HIV maintenance therapy

Liz Highleyman | 2 years ago

Two long-acting injectable antiretrovirals – cabotegravir and rilpivirine – administered once e......MORE

Viral load pilot study shows roll-out will depend on an educated workforce

Keith Alcorn | 2 years ago

For viral load testing to prevent treatment failure, drug resistance and onward transmission, treat......MORE

World’s largest study of HIV self-testing gets off the ground

Roger Pebody | 2 years ago

Early data from STAR, the largest study yet of HIV self-testing, suggests that there is a strong de......MORE

Australia adopts ambitious plan to use PrEP to ‘virtually eliminate’ HIV by 2020

Gus Cairns | 2 years ago

Australia plans an ambitious programme of pre-exposure prophylaxis (PrEP) provision for gay men at ......MORE

Market constraints and uncertainties may limit the scale-up of HIV self-testing

Roger Pebody | 2 years ago

Four different HIV self-test products are now manufactured and approved for sale in the US and Euro......MORE

Sofosbuvir/velpatasvir shows high cure rate in HIV/HCV co-infection study

Liz Highleyman | 2 years ago

The once-daily co-formulation of sofosbuvir and velpatasvir was highly effective against all hepati......MORE

Starting treatment on the day of HIV diagnosis improves retention and viral suppression, Haiti study shows

Keith Alcorn | 2 years ago

Interventions to improve linkage to care and retention in treatment which speed up the start of tre......MORE

PrEP can further reduce the risk of HIV infection after a partner starts treatment

Liz Highleyman | 2 years ago

Offering Truvada pre-exposure prophylaxis (PrEP) to the HIV-negative partner in a serodiscordant c......MORE

Young gay men can do well on PrEP, but may need more support

Liz Highleyman | 2 years ago

Young gay and bisexual men had good adherence to Truvada for pre-exposure prophylaxis (PrEP) during......MORE

SEARCH study exceeds 90-90-90 targets after 2 years of 'test and treat' for HIV in rural East Africa

Keith Alcorn | 2 years ago

A large study that embeds 'test and treat' for HIV within a larger multi-disease prevention campaig......MORE

South Africa has driven mother-to-child HIV transmission down to 4%

Carole Leach-Lemens | 2 years ago

Mother-to-child transmission (MTCT) of HIV at population level was just over 4% at 18 months follow......MORE

HIV will only be cured with combinations too, conference delegates hear

Gus Cairns | 2 years ago

Curing people of HIV infection will have to involve combinations of drugs and approaches, just as H......MORE

Progress towards 90-90-90 targets in southern Africa: find the men!

Keith Alcorn | 2 years ago

Studies of treatment cascade performance in South Africa and Namibia show large variations between ......MORE

Far fewer people drop out of HIV care in South Africa than previously thought

Roger Pebody | 2 years ago

Previous research has considerably over-estimated the number of people living with HIV who stop att......MORE

HIV criminalisation on the rise, especially in sub-Saharan Africa

Lesley Odendal | 2 years ago

Globally, 72 countries have adopted laws that specifically allow for HIV criminalisation, either be......MORE

New strategy aims to end AIDS in children by 2020

Keith Alcorn | 2 years ago

A new strategy to end paediatric AIDS launched at the 21st International AIDS Conference in Durban,......MORE

More confidence on zero risk: still no transmissions seen from people with an undetectable viral load in PARTNER study

Gus Cairns | 2 years ago

The PARTNER study, which two years ago created headlines by establishing that the chance of an HIV-......MORE

It’s all go for a new HIV vaccine efficacy trial this year

Gus Cairns | 2 years ago

A new efficacy trial for an HIV vaccine – only the seventh ever conducted in the history of the e......MORE

Comprehensive services for sex workers reduce detectable viral load, but enhanced ARV services provide no extra benefit

Roger Pebody | 2 years ago

A randomised trial in female sex workers in Zimbabwe, offering enhanced access to HIV treatment and......MORE

HIV treatment programmes need to prepare for the 'youth bulge', South African experience shows

Carole Leach-Lemens | 2 years ago

Treatment programmes in sub-Saharan Africa must prepare for a growing population of adolescents ove......MORE

PrEP use exceeds 79,000 in US pharmacy survey, but some groups lagging behind

Liz Highleyman | 2 years ago

More than 79,000 people in the US have started Truvada for pre-exposure prophylaxis (PrEP) over the......MORE

Strong association between sexual violence and African women acquiring HIV in Europe

Roger Pebody | 2 years ago

Migrant African women who have acquired HIV since moving to France are four times more likely to ha......MORE

Gains in curbing HIV epidemic could be lost without continued commitment, AIDS 2016 speakers say

Liz Highleyman | 2 years ago

Participants at the 21st International AIDS Conference (AIDS 2016), taking place this week in Durba......MORE

TB2016 demands a global commitment to end TB

Theo Smart | 2 years ago

While much of TB 2016, held on the eve of AIDS 2016 from 16-17 July 2016 was devoted to the rapidly......MORE

Progress towards 90-90-90 targets is promising, but funding is the critical step, says UNAIDS leader

Keith Alcorn | 2 years ago

The 90-90-90 targets for testing, treatment and viral suppression are achievable by 2020 in many hi......MORE

Young women treated in very early HIV infection stay HIV negative and preserve immune function

Gus Cairns | 2 years ago

A group of young South African women who were diagnosed in very early infection and immediately giv......MORE

Shortened regimen for MDR-TB shows good results for children

Lesley Odendal | 2 years ago

The use of the shortened 9-month treatment regimen for multidrug-resistant tuberculosis (MDR-TB), k......MORE

PrEP researchers now focusing on the best ways to get PrEP to people who need it

Roger Pebody | 2 years ago

Speaking to a pre-conference meeting on pre-exposure prophylaxis (PrEP) yesterday at the 21st Inter......MORE

Opioid substitution therapy improves many ART-related outcomes among people who inject drugs

Michael Carter | 2 years ago

Opioid substitution therapy has a key roll in improving antiretroviral therapy (ART)-related outcom......MORE

Most young MSM and transgender women, including those with HIV, would benefit from HPV vaccination

Michael Carter | 2 years ago

Most young gay, bisexual and other men who have sex with men (MSM) would benefit from human papillo......MORE

Incidence of liver cancer is increasing in patients with HIV/HCV co-infection

Michael Carter | 2 years ago

Incidence of liver cancer is increasing among patients with HIV co-infection, an international team......MORE

Incidence of liver cancer is increasing in people with HIV/HCV co-infection

Michael Carter | 2 years ago

Incidence of liver cancer is increasing among people with HIV co-infection, an international team o......MORE

Switching from tenofovir DF to TAF improves bone and kidney safety

Liz Highleyman | 2 years ago

People with HIV who switched from the older tenofovir disoproxil fumarate (TDF) formulation to teno......MORE

Feasible to prescribe ART to emergency department patients with suspected acute HIV infection

Michael Carter | 2 years ago

Empiric antiretroviral therapy (ART) for individuals presenting to emergency departments with suspe......MORE

HIV seroconversion is rare if Truvada PrEP is used consistently

Liz Highleyman | 2 years ago

New HIV infections occurred at a low rate of about 1 per 100 person-years among people who took dai......MORE

New integrase inhibitor bictegravir looks promising in early studies

Liz Highleyman | 2 years ago

Gilead Sciences' novel integrase inhibitor bictegravir (formerly GS-9883) demonstrated favourable p......MORE

Atripla three times weekly maintains HIV viral suppression for 24 weeks

Liz Highleyman | 2 years ago

People with undetectable viral load who switched from taking the Atripla single-tablet regimen (efa......MORE

VACS Index score can help identify HIV-positive people most at risk of neurocognitive decline

Michael Carter | 2 years ago

A combination of simple, routine blood tests may be able to predict which people living with HIV ar......MORE

VACS Index score can help identify HIV-positive patients most at risk of neurocognitive decline

Michael Carter | 2 years ago

A combination of simple, routine blood tests may be able to predict which HIV-positive patients are......MORE

Gay and bisexual people really do have poorer mental health, national US health survey shows

Gus Cairns | 2 years ago

The inclusion, for the first time, of a question about sexual orientation in a regularly-conducted ......MORE

Vaccination could have important role in control of UK HCV epidemic among people who inject drugs

Michael Carter | 2 years ago

A vaccine, even with low efficacy, could lead to meaningful reductions in the incidence and prevale......MORE

PRO 140 antibody injections maintain viral suppression in phase 2 study

Liz Highleyman | 2 years ago

Subcutaneous injections of PRO 140, a monoclonal antibody that blocks HIV entry into cells, was wel......MORE

PRO-140 antibody injections maintain viral suppression in phase 2 study

Liz Highleyman | 2 years ago

Subcutaneous injections of PRO 140, a monoclonal antibody that blocks HIV entry into cells, was wel......MORE

US National HIV Testing Day boosts numbers testing

Roger Pebody | 2 years ago

Today, June 27, is National HIV Testing Day in the United States and a study just published in Morb......MORE

ART use averting huge numbers of opportunistic infections among children living with HIV in lower-income countries

Michael Carter | 2 years ago

There has been a decrease in cases of many opportunistic infections (OIs) among children living wit......MORE

ART use averting huge numbers of opportunistic infections among HIV-positive children in lower-income countries

Michael Carter | 2 years ago

There has been a decrease in cases of many opportunistic infections (OIs) among HIV-positive childr......MORE

PrEP use is rising fast in US, but large racial disparities remain

Liz Highleyman | 2 years ago

More than 49,000 people in the US have filled prescriptions for Truvada for pre-exposure prophylaxi......MORE

Hepatitis C antigen testing could eliminate need for two-step HCV testing, reduce cost of access

Keith Alcorn | 2 years ago

Testing for hepatitis C virus core antigen could eventually replace the current two-step procedure......MORE

Gay men report a wide range of behaviours to make sex safer

Roger Pebody | 2 years ago

Gay men in the UK employ a wide range of precautionary tactics and behaviours to avoid harms during......MORE

Many US communities vulnerable to HIV outbreak due to unsafe injecting of prescription opioids

Michael Carter | 2 years ago

Research published in the online edition of the Journal of Acquired Immune Deficiency Syndromes has......MORE

Women in HIV serodiscordant relationships less likely to take PrEP consistently if they experience intimate partner violence

Michael Carter | 2 years ago

Experiencing intimate partner violence is associated with an increased risk of poor adherence to HI......MORE

People who inject drugs have other priorities ahead of PrEP

Roger Pebody | 2 years ago

People who inject drugs have fundamental concerns about HIV pre-exposure prophylaxis and the manner......MORE

HIV treatment reduces HIV transmission by 77% in South African couples

Keith Alcorn | 2 years ago

Antiretroviral treatment reduced the risk of HIV transmission by 77% in serodiscordant couples in r......MORE

HIV testing and treatment campaigns need to target women and the under 35s, says research from South Africa

Michael Carter | 2 years ago

A quarter of HIV-positive individuals in KwaZulu-Natal are unaware of their infection status, accor......MORE

Sofosbuvir/ledipasvir regimens can cost less per cure than older hepatitis C treatments

Keith Alcorn | 2 years ago

The cost of treating chronic hepatitis C with sofosbuvir/ledipasvir (Harvoni) is lower than the cos......MORE

Sofosbuvir/ledipasvir regimens can cost less per cure than older hepatitis C treatments

Liz Highleyman | 2 years ago

The cost of treating chronic hepatitis C with sofosbuvir/ledipasvir (Harvoni) is lower than the cos......MORE

HIV-positive adolescents need to be rapidly linked to specialist care to have best chances of sustaining engagement with HIV services

Michael Carter | 2 years ago

Adolescents newly diagnosed with HIV need to be rapidly incorporated into HIV care networks to have......MORE

Adolescents with HIV need to be rapidly linked to specialist care to have best chances of sustaining engagement with HIV services

Michael Carter | 2 years ago

Adolescents newly diagnosed with HIV need to be rapidly incorporated into HIV care networks to have......MORE

Less frequent CD4 and viral load monitoring safe for people doing well on ART

Michael Carter | 2 years ago

The frequency of routine monitoring for people treated with antiretrovirals with viral suppression ......MORE

Big increases in proportion of HIV-positive patients in US treated with ART and with viral suppression

Michael Carter | 2 years ago

The proportion of HIV-positive patients receiving care in the United States who accessed antiretrov......MORE

Big increases in proportion of HIV-positive people in US treated with ART and with viral suppression

Michael Carter | 2 years ago

The proportion of people living with HIV receiving care in the United States who accessed antiretro......MORE

New HCV therapies unaffordable to health systems and individuals

Michael Carter | 2 years ago

The pricing of new treatments for hepatitis C virus (HCV) means they are unaffordable for many heal......MORE

Sub-type C infection does not increase the risk of virologic failure when patients are taking tenofovir-containing first-line ART

Michael Carter | 2 years ago

There is no evidence that HIV-positive patients with sub-type C infection have an increased risk of......MORE

Sub-type C infection does not increase the risk of virologic failure when people are taking tenofovir-containing first-line ART

Michael Carter | 2 years ago

There is no evidence that HIV-positive people with sub-type C infection have an increased risk of t......MORE

UN High-Level Meeting on Ending AIDS faces battle over key populations

Keith Alcorn | 2 years ago

Activists say that a United Nations Political Declaration on Ending AIDS, due to be finalised this ......MORE

HIV self-testing has several advantages, but some barriers to HIV testing likely to remain

Roger Pebody | 2 years ago

A service offering kits for HIV self-testing in South Africa has the potential to improve uptake of......MORE

Australia shows an alternative to rationing hepatitis C treatment

Keith Alcorn | 2 years ago

The Hepatitis C Trust has announced it is considering seeking judicial review of NHS England's deci......MORE

Significant attrition at each stage of HIV care cascade in South Africa

Michael Carter | 2 years ago

There is significant attrition at each stage of the HIV care continuum in South Africa, according t......MORE

Cost is biggest barrier to PrEP in Europe, ECDC declares

Gus Cairns | 2 years ago

A meeting a month ago at the European Centre for Disease Control (ECDC) in Stockholm found that cos......MORE

Cost is biggest barrier to PrEP in Europe, ECDC report declares

Gus Cairns | 2 years ago

A meeting a month ago at the European Centre for Disease Control (ECDC) in Stockholm found that cos......MORE

France to provide universal access to hepatitis C treatment

Keith Alcorn | 2 years ago

France will provide access to hepatitis C treatment with direct-acting antivirals to everyone diagn......MORE

Many South African patients whose HIV has been diagnosed have unprotected sex with a serodiscordant partner before starting ART

Michael Carter | 2 years ago

Among a sample of South Africans living with diagnosed HIV infection in South Africa and waiting to......MORE

Many South African patients whose HIV has been diagnosed have unprotected sex with a serodiscrodant partner before starting ART

Michael Carter | 2 years ago

Among a sample of South Africans living with diagnosed HIV infection in South Africa and waiting to......MORE

Many South African people whose HIV has been diagnosed have unprotected sex with a serodiscordant partner before starting ART

Michael Carter | 2 years ago

Among a sample of South Africans living with diagnosed HIV infection in South Africa and waiting to......MORE

Two million people with HIV started treatment in 2015

Keith Alcorn | 2 years ago

At least two million people worldwide started antiretroviral treatment in 2015 alone, and 17 millio......MORE

2 million people with HIV started treatment in 2015

Keith Alcorn | 2 years ago

At least two million people worldwide started antiretroviral treatment in 2015 alone, and 17 millio......MORE

Very high levels of drug resistance seen in patients failing first-line antiretroviral therapy in Kenya

Gus Cairns | 2 years ago

A cross-sectional survey of viral load in patients attending the largest clinic providing antiretro......MORE

Very high levels of drug resistance seen in people experiencing first-line antiretroviral therapy failure in Kenya

Gus Cairns | 2 years ago

A cross-sectional survey of viral load in patients attending the largest clinic providing antiretro......MORE

Rare but severe liver side-effects reported among South African patients starting efavirenz-based ART

Michael Carter | 2 years ago

Treatment with efavirenz has been associated with rare but severe liver complications among patient......MORE

AIDS patients have increased risk of death due to non-AIDS-related cancers

Michael Carter | 2 years ago

People diagnosed with AIDS have a very high risk of dying of a non-AIDS-defining cancer, Italian in......MORE

People diagnosed with AIDS have increased risk of death due to non-AIDS-related cancers

Michael Carter | 2 years ago

People diagnosed with AIDS have a very high risk of dying of a non-AIDS-defining cancer, Italian in......MORE

Only treating patients with cirrhosis with DAAs will have limited impact on HCV epidemic in England

Michael Carter | 2 years ago

Targeting new hepatitis C virus (HCV) direct acting antivirals (DAAs) at patients with cirrhosis wi......MORE

American gay men’s use of condoms has been falling for a decade, regardless of sero-sorting or PrEP

Roger Pebody | 2 years ago

There has been a long-term decline in condom use by American gay men, researchers from the Centers......MORE

American gay men’s use of condoms has been falling for a decade, regardless of serosorting or PrEP

Roger Pebody | 2 years ago

There has been a long-term decline in condom use by American gay men, researchers from the Centers......MORE

HIV/HBV co-infection linked to worse immune recovery and death, but tenofovir improves outcomes

Liz Highleyman | 2 years ago

HIV-positive people with hepatitis B virus (HBV) co-infection had impaired CD4 cell recovery after ......MORE

Poor mental health more commonly experienced by gay and bisexual men who are younger, poorer, less educated or black

Roger Pebody | 2 years ago

While it is well established that men who have sex with men are more likely to experience poor ment......MORE

In Option B+, side-effects and needing time to think are key reasons for not taking HIV medication

Roger Pebody | 2 years ago

A qualitative study of women in Malawi who chose not to take HIV treatment as part of the country......MORE

Denmark shows first clear evidence of the success of treatment as prevention in gay men in a high income country

Gus Cairns | 2 years ago

A study by the University of California, Los Angeles, and Copenhagen University Hospital provides t......MORE

Successful diagnosis of acute/early HIV infections may have contributed to fall in HIV incidence in San Diego

Michael Carter | 2 years ago

An HIV testing programme targeting individuals with acute/early infection likely contributed to a d......MORE

HIV rapidly develops resistance to gene-editing cure technology

Gus Cairns | 2 years ago

In a setback for a novel approach to curing HIV, researchers involved in a technique that uses enzy......MORE

Does having HIV affect response to hepatitis C treatment?

Liz Highleyman | 2 years ago

A study from the US Veterans Health Administration found that HIV-positive people responded as well......MORE

Hypertension in patients with HIV associated with obesity, fat loss and previous treatment with stavudine

Michael Carter | 2 years ago

Patients with HIV have a higher prevalence of hypertension than closely matched HIV-negative contro......MORE

WHO issues new hepatitis C guidelines, EASL guidelines update forthcoming in September

Liz Highleyman | 2 years ago

In April, coinciding with the 2016 International Liver Congress in Barcelona, the World Health Orga......MORE

Men taking virologically suppressive ART have undetectable HIV in their pre-ejaculatory fluid

Michael Carter | 2 years ago

HIV is undetectable in the pre-ejaculatory fluid of men taking suppressive antiretroviral therapy, ......MORE

Small risk of sexual transmission of HIV persists through first six months of ART

Michael Carter | 2 years ago

A risk of HIV transmission to sexual partners persists for six months after the initiation of antir......MORE

US on course to end its HIV epidemic – eventually

Gus Cairns | 2 years ago

If current trends continue, the US may eventually end its HIV epidemic, a mathematical model recent......MORE

HCV associated with increased risk of cancers of the head and neck

Michael Carter | 2 years ago

Infection with hepatitis C virus (HCV) is associated with an increased risk of head and neck cancer......MORE

Hepatitis C kills more people than any other infectious disease in US, CDC says

Liz Highleyman | 2 years ago

The number of deaths due to hepatitis C is at an all-time high in the US and exceeds those attribu......MORE

Hepatitis C therapy improves quality of life for people who inject drugs, but reinfection risk remains

Keith Alcorn | 2 years ago

People on opiate substitution therapy can be successfully treated with grazoprevir/elbasvir (Zepati......MORE

High prevalence of geriatric conditions in HIV-positive patients aged over 50 in San Francisco

Michael Carter | 2 years ago

Older HIV-positive patients have a high prevalence of multiple age-related problems, investigators ......MORE

China has a long way to go before it achieves 90-90-90 targets

Michael Carter | 2 years ago

A study published in Clinical Infectious Diseases suggests that China has a long way to go before i......MORE

Which men stand to benefit most from access to PrEP?

Michael Carter | 2 years ago

New data from the PROUD pre-exposure prophylaxis (PrEP) study have identified the characteristics o......MORE

How do gay men diagnosed with HIV change their risk behaviour?

Gus Cairns | 2 years ago

To what extent do gay men modify their sexual risk behaviour after testing HIV positive? Two Austra......MORE

People treated for hepatitis C have unexpectedly high rate of liver cancer recurrence

Liz Highleyman | 2 years ago

Hepatitis C patients with cirrhosis who were treated with direct-acting antivirals had about twice ......MORE

ART use doesn't increase sexual risk among people with HIV in the UK

Michael Carter | 2 years ago

Taking antiretroviral therapy (ART) is not associated with an increased risk of condomless sex with......MORE

More targeted interventions to diagnose HIV during acute infection are needed, researchers warn

Michael Carter | 2 years ago

Men who have sex with men (MSM) diagnosed with HIV in the acute phase of HIV infection have a great......MORE

Portugal's roll-out of HCV therapy with DAAs achieves impressive results

Michael Carter | 2 years ago

Roll-out of hepatitis C virus (HCV) therapy using direct acting antivirals (DAAs) has achieved exce......MORE

First data on uptake of HIV self-testing in the UK

Roger Pebody | 2 years ago

Between April 2015 and February 2016, almost 28,000 people have paid £29.95 for a kit allowing the......MORE

Opt-out HIV testing in a hospital emergency department may cost less than managing two patients with undiagnosed HIV

Roger Pebody | 2 years ago

Opt-out HIV testing in accident and emergency departments in areas of high HIV prevalence is likely......MORE

Considerable overlap between HIV and shigellosis epidemics in the UK

Michael Carter | 2 years ago

Approximately a third of cases of non-travel-related Shigella dysentery in the UK involve HIV-posit......MORE

Considerable overlap between HIV and Shigella epidemics in the UK

Michael Carter | 2 years ago

Approximately a third of cases of non-travel-related Shigella dysentery in the UK involve HIV-posit......MORE

Online privacy concerns limit the reach of sexual health messages on social media

Roger Pebody | 2 years ago

The way in which individuals manage their identities on Facebook, for example avoiding publication ......MORE

Multiple social and health factors associated with irregular attendance at London HIV clinics

Roger Pebody | 2 years ago

People who miss appointments for HIV care are more likely to have money problems, childcare respons......MORE

DAAs achieve excellent outcomes in real-world settings

Michael Carter | 2 years ago

Hepatitis C virus (HCV) therapy with direct acting antivirals (DAAs) is as effective in real-world ......MORE

Model suggests there are fewer people with HIV in the US than thought, and more of them on therapy

Gus Cairns | 2 years ago

A study comparing recorded diagnoses of HIV with subsequent records of viral load and CD4 tests sug......MORE

High incidence of HCV re-infection among HIV-positive MSM in Western Europe

Michael Carter | 2 years ago

There is a very high incidence of hepatitis C virus (HCV) re-infection among HIV-positive men who h......MORE

Sofosbuvir/velpatasvir cures HCV in 95% of people with HCV and HIV co-infection

Liz Highleyman | 2 years ago

A dual regimen of sofosbuvir plus velpatasvir was well tolerated and highly effective against hepat......MORE

Six weeks of sofosbuvir/ledipasvir is enough to cure acute hepatitis C in HIV-negative people

Liz Highleyman | 2 years ago

A regimen of sofosbuvir/ledipasvir (Harvoni) taken for six weeks cured all patients with genotype 1......MORE

Tenofovir alafenamide works well against hepatitis B with less effect on bones and kidneys

Liz Highleyman | 2 years ago

The new tenofovir alafenamide (TAF) pro-drug is as potent against hepatitis B virus (HBV) as the cu......MORE

Low-cost generic hepatitis C drugs match branded products in viral response

Keith Alcorn | 2 years ago

Generic versions of direct-acting antivirals purchased from China and India by people unable to obt......MORE

Shifting hepatitis C treatment to primary care providers could expand availability

Liz Highleyman | 2 years ago

Hepatitis C treatment managed by non-specialists such as primary care physicians and nurse practiti......MORE

Sofosbuvir/velpatasvir + GS-9857 works well for treatment-experienced hepatitis C patients

Liz Highleyman | 2 years ago

A triple combination of Gilead Sciences' sofosbuvir, velpatasvir and GS-9857 demonstrated a high s......MORE

Hepatitis C treatment may not be enough to stop the progress of advanced liver disease, or reduce liver transplant need

Keith Alcorn | 2 years ago

Doctors need to have “full and frank” discussions with patients about the potential risks and b......MORE

$300 hepatitis C combination to enter clinical trials

Keith Alcorn | 2 years ago

The Drugs for Neglected Diseases Initiative (DNDI) is launching clinical trials in Thailand and Mal......MORE

People not taking HIV treatment feel under pressure to ‘do the right thing’

Roger Pebody | 2 years ago

Australian people living with HIV who have chosen not to take antiretrovirals and who have doubts a......MORE

Resistance to anti-HIV drugs in steep decline in Switzerland

Michael Carter | 2 years ago

Prevalence of antiretroviral drug resistance has declined significantly among patients in Switzerla......MORE

Primary care doctors and nurse practitioners can successfully treat people with hepatitis C

Liz Highleyman | 2 years ago

Direct-acting antiviral therapy for hepatitis C delivered by non-specialists such as primary care p......MORE

A third of MSM with HIV/HCV co-infection have HCV in their semen

Michael Carter | 2 years ago

Hepatitis C virus (HCV) is present in the semen of a third of co-infected HIV-positive men who have......MORE

VRC01 antibody delays but does not prevent HIV rebound after antiretroviral treatment interruption

Liz Highleyman | 2 years ago

VRC01, a broadly neutralising antibody targeting HIV's CD4 binding site, was able to modestly delay......MORE

More people with HIV are achieving viral suppression in US, but about 40% remain above transmission thresholds

Liz Highleyman | 2 years ago

A growing proportion of people with HIV are reaching an undetectable viral load on antiretroviral t......MORE

Indian study proves that more people virally suppressed in a population equals fewer HIV infections

Gus Cairns | 2 years ago

The proportion of people living with HIV in a population who have a detectable viral load is much m......MORE

Simple outreach on dating websites increases HIV testing rate

Roger Pebody | 2 years ago

A simple online outreach intervention – in which a health educator engaged in conversation and re......MORE

No adverse social consequences from early ART initiation in West Africa

Michael Carter | 2 years ago

Early initiation of antiretroviral therapy (ART) does not have negative social consequences, invest......MORE

HCV epidemic in North America peaked between 1940 and 1965 with medical procedures likely source of most infections

Michael Carter | 2 years ago

The spread of hepatitis C virus (HCV) in North America peaked between 1940 and 1965, according to r......MORE

African women in London with poor adherence feel that HIV treatment is difficult and unrelenting

Roger Pebody | 2 years ago

A qualitative study with West African women living in London who have difficulties adhering to thei......MORE

Long-acting oral antiretroviral MK-8591 could represent 'paradigm shift' in HIV treatment and prophylaxis

Michael Carter | 2 years ago

An investigational antiretroviral agent that maintains drug levels that are able to inhibit HIV up ......MORE

Antidepressant modestly improves HIV-related cognitive impairment

Liz Highleyman | 2 years ago

The SSRI antidepressant paroxetine (Paxil) was associated with modest improvement in cognitive func......MORE

Gene therapy snips HIV out of infected cells and makes uninfected cells resistant

Gus Cairns | 2 years ago

For the first time, researchers have used a gene-editing technique already used to produce cells re......MORE

Gene therapy snips HIV out of infected cells and makes uninfected cells resistant

Gus Cairns | 2 years ago

For the first time, researchers have used a gene-editing technique already used to produce cells re......MORE

High-risk anal HPV infections persist in a significant proportion of HIV-negative MSM

Michael Carter | 2 years ago

Anal infection with human papillomavirus (HPV) types associated with a high risk of pre-cancerous a......MORE

Isoniazid alone prevents tuberculosis in people with advanced HIV, urine test may lower mortality

Liz Highleyman | 2 years ago

Using isoniazid alone to prevent the development of active tuberculosis (TB) in people with advance......MORE

Tailored programmes encourage black gay men to start and stay on PrEP in US study

Liz Highleyman | 2 years ago

Providing culturally tailored support programmes for black men who have sex with men can increase t......MORE

England’s PrEP policy in disarray after NHS U-turn

Roger Pebody | 2 years ago

Activists, individuals at risk of HIV, and clinicians have reacted with anger to an official U-turn......MORE

Opt-out HIV/HBV/HCV testing for patients attending emergency departments identifies significant number of new infections

Michael Carter | 2 years ago

A pilot study involving nine UK emergency departments has shown that routine, opt-out testing for H......MORE

ART has averted over 850,000 HIV-related opportunistic infections in low and middle income countries

Michael Carter | 2 years ago

Rollout of antiretroviral therapy (ART) in low and middle income countries has averted over 850,000......MORE

Combination inhibitor BMS-986197 demonstrates good activity against HIV in early study

Liz Highleyman | 2 years ago

A long-acting bio-engineered molecule with a triple mechanism of action demonstrated potent antivir......MORE

Starting HIV therapy associated with improvements in liver function, especially when viral load is suppressed

Michael Carter | 2 years ago

Starting antiretroviral therapy is associated with improvements in liver function in HIV-positive m......MORE

High sexually transmitted infection rates among men on PrEP supports more frequent monitoring

Liz Highleyman | 2 years ago

Participants taking tenofovir/emtricitabine (Truvada) for pre-exposure prophylaxis (PrEP) continued......MORE

HIV-related factors increase risk of stroke

Theo Smart | 2 years ago

HIV-related risk factors seem to increase the risk of stroke – the sudden death of brain cells du......MORE

Sofosbuvir/velpatasvir for hepatitis C can be administered with most antiretrovirals

Liz Highleyman | 2 years ago

Sofosbuvir/velpatasvir, a forthcoming combination that effectively treats all hepatitis C virus (HC......MORE

Transgender people are at high risk for HIV, but too little is known about prevention and treatment for this population

Liz Highleyman | 2 years ago

Transgender women have among the highest rates of HIV infection but little is known about HIV preva......MORE

Rapid rise in PrEP awareness in US gay men, but only 5% have used PrEP

Roger Pebody | 2 years ago

Large internet surveys of American gay men show that the proportion who have heard of pre-exposure ......MORE

Indiana HIV epidemic among people who inject drugs is controlled, but ongoing vigilance is needed

Liz Highleyman | 2 years ago

Extensive epidemiological investigation followed by prevention and treatment interventions have lar......MORE

Ravidasvir plus sofosbuvir demonstrates high cure rate for people with hepatitis C genotype 4

Liz Highleyman | 2 years ago

Sofosbuvir plus the investigational HCV NS5A inhibitor ravidasvir, with or without ribavirin, cured......MORE

START study shows that people starting HIV treatment earlier have better quality of life

Roger Pebody | 2 years ago

Rather than treatment side-effects having a negative impact on people’s quality of life when they......MORE

South Africa’s XDR-TB epidemic is due to transmission rather than evolution of resistant strains

Theo Smart | 2 years ago

A study in KwaZulu-Natal, South Africa, evaluating the social networks as well as clinical and geno......MORE

Maraviroc may work as PrEP in combination with another drug – but probably not by itself

Gus Cairns | 2 years ago

Two studies presented at the Conference on Retroviruses and Opportunistic Infections (CROI 2016) ou......MORE

Expanding treatment and PrEP could prevent 185,000 new HIV infections, US CDC says

Liz Highleyman | 2 years ago

Increasing diagnosis, care and treatment of people living with HIV could lead to a large decrease i......MORE

Modest kidney function decline in people taking Truvada for PrEP supports need for monitoring

Liz Highleyman | 2 years ago

Participants taking tenofovir/emtricitabine (Truvada) for pre-exposure prophylaxis (PrEP) in two ma......MORE

Rate of entry into HIV care improved by personalised counselling

Keith Alcorn | 2 years ago

Entry into HIV care can be increased by around 40% if people receive a point-of-care CD4 test and c......MORE

Studies probe retention in HIV care for women who start antiretroviral treatment during pregnancy

Carole Leach-Lemens | 2 years ago

Engaging lay counsellors to provide a combination package of evidence-based interventions in Nyanza......MORE

Experimental TLR7 agonist suppresses HIV-like virus in monkeys after ART interruption

Liz Highleyman | 2 years ago

GS-9620, an investigational toll-like receptor or TLR7 agonist, led to immune activation in a stud......MORE

Study does not support routine HPV quadrivalent vaccination to protect against anal cancer in older people living with HIV

Keith Alcorn | 2 years ago

The quadrivalent HPV vaccine Gardasil does not protect older adults with HIV against persistent ana......MORE

‘On-demand’ rectal microbicide gel has reasonable tolerability and acceptability – daily less so

Gus Cairns | 2 years ago

Results from the MTN-017 study of 1% tenofovir gel as a rectal microbicide were presented to the CR......MORE

Life expectancy in HIV positive people in the US still lags 13 years behind HIV negative people

Gus Cairns | 2 years ago

A study presented at the CROI 2016 conference comparing life expectancies of HIV-positive and HIV-n......MORE

Life expectancy in HIV-positive people in the US still lags 13 years behind HIV-negative people

Gus Cairns | 2 years ago

A study presented at the Conference on Retroviruses and Opportunistic Infections (CROI 2016) compar......MORE

Option B+ has enabled Malawi to make significant progress towards 90-90-90

Roger Pebody | 2 years ago

In four years Malawi’s treatment cascade for pregnant women has been transformed so that the prop......MORE

Condom use in French PrEP trial: half only used PrEP, a quarter used condoms and PrEP, one in six used neither

Gus Cairns | 2 years ago

An analysis of condom use in the placebo-controlled phase of the French IPERGAY trial of intermitte......MORE

Empirical TB treatment comes up short again

Theo Smart | 2 years ago

A South African trial has found that a strategy allowing primary care nurses to quickly provide emp......MORE

Sofosbuvir/ledipasvir for 6 weeks cures HCV in HIV-positive people with acute HCV if viral load is low

Liz Highleyman | 2 years ago

An interferon- and ribavirin-free regimen of sofosbuvir/ledipasvir (Harvoni) taken for just 6 weeks......MORE

Large-scale household TB screening shows feasibility in PopART trial

Keith Alcorn | 2 years ago

Offering TB screening as part of a home-based HIV testing intervention has the potential to identif......MORE

Almost-certain case of PrEP failure due to drug resistance reported at CROI 2016

Gus Cairns | 2 years ago

A case report of a man in Toronto who became infected with a multi-drug-resistant strain of HIV des......MORE

Almost-certain case of PrEP failure due to drug resistance reported at CROI conference

Gus Cairns | 2 years ago

A case report of a man in Toronto who became infected with a multi-drug-resistant strain of HIV des......MORE

Early antiretroviral therapy reduces the risk of infection-related cancers

Keith Alcorn | 2 years ago

People who started antiretroviral therapy at a CD4 cell count above 500 had a significantly lower ......MORE

HIV in the brain: new tools and treatment to keep your mind beautiful

Theo Smart | 2 years ago

In the future, HIV-associated neurocognitive disorder (HAND) may become less common because of the ......MORE

Removing clinic barriers to rapid initiation of ART in Uganda enables 70% to start on the same day

Roger Pebody | 2 years ago

Making point-of-care CD4 count diagnostics available, revising adherence counselling requirements a......MORE

Dolutegravir safe and highly effective in older children

Carole Leach-Lemens | 2 years ago

Dolutegravir (DTG) plus optimised background regimen (OBR) is safe, well tolerated and provides vir......MORE

Long-acting PrEP injection tolerable and acceptable for male volunteers, but dose adjustment needed

Gus Cairns | 2 years ago

The Conference on Retroviruses and Opportunistic Infections (CROI 2016) heard results yesterday fro......MORE

Tenofovir alafenamide PrEP protects monkeys from infection, but rectal and vaginal levels in humans may be too low

Liz Highleyman | 2 years ago

A proof-of-concept study showed that the new tenofovir alafenamide (TAF) plus emtricitabine (FTC, E......MORE

TAF/emtricitabine maintains viral suppression as well as TDF regimens with less bone and kidney toxicity

Liz Highleyman | 2 years ago

A fixed-dose coformulation of tenofovir alafenamide (TAF) and emtricitabine (FTC, Emtriva), combine......MORE

PopART trial shows feasibility of reaching 90-90-90 targets for testing and treatment coverage in Zambia and South Africa

Keith Alcorn | 2 years ago

Early findings from the PopART study of the impact of a test-and-treat strategy on antiretroviral t......MORE

Botswana close to reaching the 90-90-90 testing and treatment targets

Keith Alcorn | 2 years ago

Botswana is already close to reaching the 90-90-90 target for testing, treatment and viral suppres......MORE

Cotrimoxazole prophylaxis provides no benefit for HIV-exposed uninfected children

Carole Leach-Lemens | 2 years ago

Challenging current guidelines, prolonged use of cotrimoxazole (CTX) may not be necessary for HIV-e......MORE

Partner notification feasible and effective in African settings

Roger Pebody | 2 years ago

Partner notification programmes, offering HIV testing to the sexual partners of people newly diagno......MORE

Very high levels of chemsex and ‘slamsex’ seen in HIV-positive men attending English/Welsh HIV clinics

Gus Cairns | 2 years ago

A survey of HIV-positive patients attending 30 HIV clinics in England and Wales, presented at the C......MORE

Option B+ cuts mother-to-child HIV transmission dramatically in Malawi

Carole Leach-Lemens | 2 years ago

Among women on antiretroviral therapy (ART) prior to pregnancy, early mother-to-child transmission ......MORE

Starting HIV treatment at first clinic visit improves outcomes in African study

Liz Highleyman | 2 years ago

A programme to accelerate the process of HIV diagnosis, preparation and starting antiretroviral the......MORE

Major disparities persist in lifetime risk of HIV diagnosis in the US

Liz Highleyman | 2 years ago

The lifetime risk of being diagnosed with HIV in the US has decreased overall during the past decad......MORE

During pregnancy, offering HIV testing at home doubles the proportion of male partners who test

Roger Pebody | 2 years ago

A programme of home visits, partner education and HIV testing for couples in Kenya was able to doub......MORE

People with HIV considerably overestimate their chance of infecting someone

Gus Cairns | 2 years ago

Only a small proportion of HIV-positive people in a large US treatment study, ACTG A5257, regarded ......MORE

Bone density recovers quickly after stopping PREP

Keith Alcorn | 2 years ago

Bone mineral density recovers within six months of stopping pre-exposure prophylaxis (PrEP) contain......MORE

Dose-finding trials of antibody-based drugs for HIV prevention will start soon

Gus Cairns | 2 years ago

The next generation of pre-exposure prophylaxis (PrEP), and even of HIV treatment, may consist of a......MORE

Long-acting injectable cabotegravir + rilpivirine works well as HIV maintenance therapy

Liz Highleyman | 2 years ago

A combination of two long-acting injectable antiretrovirals, cabotegravir and rilpivirine, given on......MORE

Early antiretroviral therapy has no impact on marker of early cardiovascular disease

Keith Alcorn | 2 years ago

Starting treatment at a CD4 cell count above 500 does not lead to improvement in an important early......MORE

Women and African-Americans with HIV have a higher risk of stroke

Keith Alcorn | 2 years ago

The risk of stroke among people living with HIV is highest among people with unsuppressed viral loa......MORE

Tenofovir treatment raises the risk of broken bones

Keith Alcorn | 2 years ago

Treatment containing tenofovir is associated with a higher risk of bone fractures in people living ......MORE

Vaginal rings containing antiretroviral moderately effective in preventing HIV – but not in the youngest women

Gus Cairns | 2 years ago

The results of two studies announced today at the annual Conference on Retroviruses and Opportunist......MORE

Survey shows more than 800,000 people in US have hepatitis B, half of them Asian

Liz Highleyman | 2 years ago

Although nearly 70 million people in the US have been vaccinated against hepatitis B virus (HBV), t......MORE

Direct-acting antivirals reduce cryoglobulinemia in hepatitis C

Keith Alcorn | 2 years ago

Treatment with direct-acting antivirals not only cures people of hepatitis C, but can also rapidly ......MORE

What do women want from a vaginal microbicide ring?

Gus Cairns | 2 years ago

In order to maximise confidence in its effectiveness, a vaginal microbicide ring for women would id......MORE

Telephone intervention can boost retention in care for HIV-positive patients with mental health and drug/alcohol problems

Michael Carter | 2 years ago

Retention in HIV care among patients with mental health and/or drug and alcohol problems can be imp......MORE

PrEP use rising among high-risk gay men in Washington State

Liz Highleyman | 2 years ago

More than 20% of gay and bisexual men in Washington State considered to be at high risk for HIV in......MORE

HIV-infected vaginal cells do not transmit HIV if plasma viral load is undetectable, researchers find

Gus Cairns | 2 years ago

A group of researchers, in experiments on mice, have cleared up an important question about HIV tra......MORE

Survival and outcome analysis shows that selected HIV-positive patients are good candidates for liver and kidney transplant

Michael Carter | 2 years ago

Liver and kidney transplant can be justified for carefully selected HIV-positive patients, research......MORE

Moderate alcohol consumption may be more harmful to people with HIV

Keith Alcorn | 2 years ago

Safe drinking limits for people living with HIV may be lower than the recommendations for the rest ......MORE

Neurosyphilis present in 90% of HIV-positive patients with early syphilis in Warsaw

Michael Carter | 2 years ago

The overwhelming majority of early syphilis cases in patients with HIV in Warsaw had neurological i......MORE

African Americans have highest HIV incidence, lowest rate of consistent care

Liz Highleyman | 2 years ago

African Americans in the US have the highest rate of new HIV infections, but black people living w......MORE

Women under-represented in HIV clinical trials

Roger Pebody | 2 years ago

Less than a quarter of people taking part in clinical trials for antiretroviral medications are wom......MORE

Combination nanotherapy drastically reduces the amount of HIV produced by cells in mice

Gus Cairns | 2 years ago

A combination of fine-particle formulations of the drugs atazanavir and ritonavir, plus an immune-d......MORE

Combination nanotherapy drastically reduces the amount of HIV inside cells in mice

Gus Cairns | 2 years ago

A combination of fine-particle formulations of the drugs atazanavir and ritonavir, plus an immune-d......MORE

Bladder cancer occurring earlier in people with HIV, and cases more difficult to treat, French study finds

Michael Carter | 2 years ago

The frequency of bladder cancer is elevated in patients with HIV, investigators from Paris report i......MORE

Opt-out approach can boost HIV testing rates

Roger Pebody | 2 years ago

A large randomised study in an emergency department in San Francisco clearly shows that an ‘opt-o......MORE

Broad range of risk factors associated with mild cognitive impairment in HIV-positive men on ART

Michael Carter | 2 years ago

A broad range of factors are associated with cognitive impairment in middle-aged HIV-positive men, ......MORE

Tenofovir resistance may develop after HIV treatment failure in over half in sub-Saharan Africa

Keith Alcorn | 2 years ago

More than half of people who experienced failure of a tenofovir-based antiretroviral regimen in sub......MORE

Tenofovir resistance may develop in more than half of patients failing treatment in sub-Saharan Africa

Keith Alcorn | 2 years ago

More than half of people who experienced failure of a tenofovir-based antiretroviral regimen in sub......MORE

New Merck combination pill Zepatier approved for hepatitis C treatment in the United States

Keith Alcorn | 2 years ago

Merck has received a US license for its direct-acting antiviral combination of grazoprevir and elba......MORE

Criminal laws on HIV transmission make little difference to sexual behaviour – or may make condomless sex more likely

Roger Pebody | 2 years ago

A study comparing the sexual behaviour of American gay men living in states with or without laws th......MORE

London sexual health clinics step up their support for people buying PrEP online

Roger Pebody | 2 years ago

Several large sexual health clinics in London and Brighton have responded to the growing numbers of......MORE

US study shows importance of access to chemotherapy for HIV-positive patients with Hodgkin lymphoma

Michael Carter | 2 years ago

HIV is associated with poorer outcomes in patients diagnosed with Hodgkin lymphoma, according to US......MORE

People taking a large number of non-HIV-related medications more likely to stop or change HIV drugs

Michael Carter | 2 years ago

HIV-positive patients who are taking a large number of medications for the treatment of non-HIV-rel......MORE

New PrEP studies will be a challenge, statisticians warn

Gus Cairns | 2 years ago

Two statisticians involved in the PROUD and iPrEx trials of pre-exposure prophylaxis (PrEP) warn th......MORE

Model suggests HIV vaccine still has key role in ending AIDS

Liz Highleyman | 2 years ago

Even a modestly effective HIV vaccine would likely be cost-effective and could make a major contri......MORE

Cardiovascular disease risk is higher for people with hepatitis C

Keith Alcorn | 2 years ago

People with hepatitis C are at higher risk of dying from cardiovascular disease suffering a stroke ......MORE

D:A:D study: long-term treatment with tenofovir associated with increased risk of serious liver disease

Michael Carter | 2 years ago

Long-term therapy with the antiretroviral drug tenofovir increases the risk of end-stage liver dise......MORE

Electrocautery ablation only partially effective as a treatment for high-grade pre-cancerous anal lesions in HIV-positive gay men

Michael Carter | 2 years ago

Electrocautery ablation is only partially effective as a treatment for high-grade pre-cancerous ana......MORE

High rates of cervical disease and low rates of screening among women with HIV in Denmark

Michael Carter | 2 years ago

Women with HIV have a higher incidence of cervical dysplasia – pre-cancerous cell changes – com......MORE

Efavirenz-based treatment is safe and effective for young children with HIV exposed to nevirapine for PMTCT

Michael Carter | 2 years ago

Efavirenz-based treatment is a safe and effective treatment option for children living with HIV pre......MORE

PrEP, plus increased testing and treatment, could prevent nearly half of HIV infections in gay men in the UK by 2020

Gus Cairns | 2 years ago

A new British mathematical modelling study published in The Lancet HIV has found that adding pre-e......MORE

High rates of modifiable cancer risk factors present in Western HIV-positive patients

Michael Carter | 2 years ago

The prevalence of potentially modifiable risk factors for some cancers is “extraordinarily high......MORE

High prevalence of anal infection with high-risk HPV types among HIV-positive women in France

Michael Carter | 2 years ago

A large proportion of women living with HIV in a national study have an anal infection with types o......MORE

Two cases of PrEP failure on solo tenofovir pose significant research questions

Gus Cairns | 2 years ago

A report originally presented to the 2015 BHIVA conference last year details two cases where therap......MORE

MDR-TB treatment: Six drugs better than five

Keith Alcorn | 2 years ago

A regimen containing six drugs was more likely to cure multi-drug resistant tuberculosis (MDR-TB) t......MORE

Middle-aged people living with HIV have an increased risk of frailty

Michael Carter | 2 years ago

Middle-aged people living with HIV have an increased risk of frailty compared with their peers with......MORE

Not having enough food linked with lower chances of sustained viral suppression for ART-treated breastfeeding mothers in Uganda

Michael Carter | 2 years ago

Not having enough food is associated with poorer chances of achieving a sustained viral suppression......MORE

Hepatitis C virus linked to increased risk of Parkinson's disease, studies show

Liz Highleyman | 2 years ago

People with hepatitis C virus (HCV) infection may be more likely to develop Parkinson's disease, e......MORE

HIV-positive patients lost to follow-up successfully identified and re-engaged with care by programme in LA County

Michael Carter | 2 years ago

A programme in Los Angeles County successfully re-engaged and retained patients who dropped out of ......MORE

LAM point-of-care TB testing reduces mortality in people with HIV/TB co-infection in hospital

Lesley Odendal | 2 years ago

All-cause 8-week mortality is reduced by rapid point-of-care urine-based testing for tuberculosis (......MORE

Annual testing and scale-up of PrEP could slow the Dutch gay HIV epidemic

Roger Pebody | 2 years ago

Phylogenetic analysis of the source of HIV infections in Dutch gay men over more than a decade show......MORE

Xpert MTB/RIF testing has reduced MDR-TB treatment delays in South Africa

Lesley Odendal | 2 years ago

Although the introduction of the Xpert MTB/RIF test for TB and drug-resistant TB has improved the ......MORE

Lessons learnt from the history of contraception are relevant for the implementation of PrEP

Roger Pebody | 2 years ago

Achieving a widespread and appropriate use of pre-exposure prophylaxis (PrEP) will take several yea......MORE

One in eight children with confirmed TB have drug-resistant TB in Cape Town

Lesley Odendal | 2 years ago

One in eight children with confirmed TB have drug-resistant TB in Cape Town, South Africa, accordin......MORE

Malawian study provides strong evidence that HIV infection is an important risk factor for stroke

Michael Carter | 2 years ago

HIV infection is an important risk factor for stroke among adults in Malawi, investigators report i......MORE

HIV salvage regimens can safely omit NRTIs, says US study

Michael Carter | 2 years ago

Nucleoside reverse transcriptase inhibitors (NRTIs) can be safely omitted from HIV salvage therapy,......MORE

DAAs could halt HCV epidemic in US – but only with near-universal testing and big increase in treatment rates

Michael Carter | 2 years ago

Treatment using direct-acting agents (DAA) could have a major impact on the hepatitis C virus (HCV)......MORE

A quarter of people with HCV initially refused access to sofosbuvir/lepidasvir, says US study, but most successfully appeal

Michael Carter | 2 years ago

Insurers deny almost a quarter of requests for sofosbuvir/lepidasvir (Harvoni) to treat people with......MORE

Community care workers boost TB case finding among hard-to-reach adults

Lesley Odendal | 2 years ago

Community care worker active case finding is an effective tool for increasing TB case detection, ac......MORE

Previous AIDS-related pulmonary disease associated with lung cancer risk for people with HIV

Michael Carter | 2 years ago

AIDS-related pulmonary disease is a major factor in the increased risk of lung cancer seen in peopl......MORE

Low implementation of Xpert MTB/RIF among HIV/TB co-infected adults in 19 low- and middle-income countries

Lesley Odendal | 2 years ago

Three quarters of people with HIV/TB co-infection did not receive Xpert MTB/RIF testing for TB diag......MORE

Large UK study shows low rates of HIV testing, even among those who think they are at risk of HIV

Roger Pebody | 2 years ago

A major household survey of adults in the UK shows that, even among people who perceive themselves ......MORE

Evidence for PrEP efficacy grows, but implementation presents challenges

Liz Highleyman | 2 years ago

Pre-exposure prophylaxis (PrEP) was a major topic at the 2015 National HIV Prevention Conference (N......MORE

Tenofovir alafenamide fumarate at what price? No more than $1000 a year above existing tenofovir formulation, says model

Michael Carter | 2 years ago

The superior safety of the tenofovir analogue tenofovir alafenamide fumarate (TAF) over tenofovir d......MORE

Two-drug ART with dolutegravir-lamivudine would be cost-effective and achieve substantial cash savings

Michael Carter | 2 years ago

Virologically suppressive first-line antiretroviral treatment with a two-drug regimen of dolutegrav......MORE

US syringe funding ban impedes HIV and hepatitis C prevention

Liz Highleyman | 2 years ago

Providing sterile syringes is a proven effective way to prevent HIV and hepatitis C virus (HCV) inf......MORE

UK maintains the largest HIV epidemic in western Europe...

Gus Cairns | 2 years ago

The annual surveillance report released recently by the European Centre for Disease Prevention and ......MORE

UK maintains the largest HIV epidemic in western Europe

Gus Cairns | 2 years ago

The annual surveillance report released recently by the European Centre for Disease Prevention and ......MORE

Sofosbuvir/daclatasvir combination could be produced for $200 per hepatitis C cure

Keith Alcorn | 2 years ago

Month-by-month tracking of the prices paid in India for the chemicals used to make hepatitis C dire......MORE

Sofosbuvir / daclatasvir combination could be produced for $200 per hepatitis C cure

Keith Alcorn | 2 years ago

Month-by-month tracking of the prices paid in India for the chemicals used to make hepatitis C dire......MORE

Drug resistance acquired during HIV PrEP rapidly disappears after medication is discontinued

Michael Carter | 2 years ago

Drug resistance acquired in rare cases of HIV infection during treatment with pre-exposure prophyla......MORE

Grazoprevir/elbasvir cures more than 90% of people with HIV/HCV co-infection

Liz Highleyman | 2 years ago

Merck's grazoprevir/elbasvir combination cured 93% of people with HIV and hepatitis C co-infection,......MORE

Death during MDR-TB treatment more likely in people with HIV and underweight or most drug-resistant patients

Keith Alcorn | 2 years ago

People living with HIV, those who are underweight and those with more extensive drug resistance are......MORE

National HIV Prevention Conference highlights progress and disparities

Liz Highleyman | 2 years ago

Pre-exposure prophylaxis (PrEP), integration of prevention and treatment services, and initiatives ......MORE

United States faces biggest burden of hepatitis C treatment costs before 2020

Keith Alcorn | 2 years ago

The cost of treating hepatitis C is likely to decline dramatically over the next decade in the Unit......MORE

New HIV cases decline in US, but population and geographic disparities persist

Liz Highleyman | 2 years ago

HIV diagnoses have declined by nearly 20% overall during the past decade but progress has been une......MORE

9-month MDR-TB regimen cures 82% in African study

Keith Alcorn | 2 years ago

A nine-month standardised treatment regimen for multi-drug resistant tuberculosis (MDR-TB) cured 82......MORE

San Francisco reports progress in 'Getting to Zero' HIV prevention and treatment effort

Liz Highleyman | 2 years ago

San Francisco made good progress in HIV prevention and treatment during 2015, and its successes ha......MORE

San Francisco reports progress in 'Getting to Zero' HIV prevention and treatment effort

Keith Alcorn | 2 years ago

San Francisco made good progress in HIV prevention and treatment during 2015, and its successes ha......MORE

Coffee consumption linked to reduced liver fibrosis in people with HBV, HCV and NAFLD

Liz Highleyman | 2 years ago

Drinking coffee was associated with lower liver stiffness – a non-invasive measure used to estima......MORE

Gay men starting to use crystal meth usually increase their sexual risk taking

Roger Pebody | 2 years ago

A study which followed the same group of gay men over several years has found that individuals who ......MORE

Australian survey finds that less than a third of gay men have committed relationships with just one partner

Gus Cairns | 2 years ago

A large survey conducted through gay dating sites and Facebook in Australia has found that previous......MORE

Ipergay PrEP study results published

Gus Cairns | 2 years ago

The results from the Ipergay study of intermittent pre-exposure prophylaxis (PrEP) were published i......MORE

WHO issues recommendations on linkage to care, retention, to help bring HIV treatment to all

Keith Alcorn | 2 years ago

The World Health Organization has issued new recommendations on how to organise services in order t......MORE

Many more people could benefit from HIV PrEP but not enough doctors are aware, says CDC

Liz Highleyman | 2 years ago

One-quarter of gay and bisexual men in the US and one-fifth of people who inject drugs -- but less......MORE

For African migrants in Europe, destitution shapes sexual behaviour and HIV risk

Roger Pebody | 2 years ago

For African migrants recently arrived in France, periods without a residence permit, secure housing......MORE

Two-drug maintenance therapy keeps viral load suppressed and may even have advantages over traditional ART

Michael Carter | 2 years ago

Two-drug antiretroviral therapy (ART) consisting of ritonavir-boosted atazanavir and lamivudine has......MORE

High HCV cure rate demonstrated for people retreated after failure of short course direct-acting antiviral therapy

Liz Highleyman | 2 years ago

People with hepatitis C who did not achieve sustained virological response with a prior short cours......MORE

HIV-related wasting can have long-term consequences

Michael Carter | 2 years ago

HIV-associated wasting can have a long-term impact on physical function and quality of life, accord......MORE

Dutch research identifies relationship between HIV clinic characteristics and retention of patients in care

Michael Carter | 2 years ago

Dutch research published in the online edition of AIDS has provided insights into the relationship ......MORE

Triple DAA regimen cures hepatitis C patients with rapid response in just 3 weeks

Liz Highleyman | 2 years ago

Response-guided therapy using an all-oral regimen of three direct-acting antivirals cured a majori......MORE

Clinical impact of effective HCV DAAs: referrals for liver transplant drop after their introduction

Michael Carter | 2 years ago

The number of hepatitis C virus (HCV)-related referrals for liver transplant has declined significa......MORE

France approves PrEP

Gus Cairns | 2 years ago

In a historic move, France has become the first country outside the USA, and the first country with......MORE

Study reveals potential challenges for scaling up of HCV therapy in UK

Michael Carter | 2 years ago

A large proportion of patients with chronic hepatitis C virus (HCV) infection in the UK have co-mor......MORE

Liver fibrosis improves after successful treatment for hepatitis C

Liz Highleyman | 2 years ago

A majority of people with chronic hepatitis C and advanced fibrosis or cirrhosis showed improvement......MORE

Widely-used anti-alcoholism drug wakes up dormant HIV-infected cells

Gus Cairns | 2 years ago

An Australian research team has found that disulfiram, a long-established and safe drug used primar......MORE

Daclatasvir and sofosbuvir with ribavirin cures 90% of people with genotype 3 hepatitis C

Liz Highleyman | 2 years ago

An all-oral combination of daclatasvir, sofosbuvir and ribavirin taken for 12 or 16 weeks led to hi......MORE

Daclatasvir plus sofosbuvir works well for people with genotype 3 hepatitis C and advanced liver disease in real-world clinical practice

Liz Highleyman | 2 years ago

Interferon-free treatment with daclatasvir plus sofosbuvir, with or without ribavirin, led to susta......MORE

Tenofovir during pregnancy reduces risk of mother-to-child hepatitis B virus transmission

Liz Highleyman | 2 years ago

Women with chronic hepatitis B and high viral load who were treated with tenofovir (Viread) during ......MORE

UK’s latest HIV figures show the need to scale up HIV testing and prevention

Roger Pebody | 2 years ago

The latest annual report by Public Health England shows that, although the number of gay men who ha......MORE

New AbbVie hepatitis C combination cures 93%-97% with genotype 3

Keith Alcorn | 2 years ago

A combination of two experimental direct-acting antivirals developed by AbbVie cured 93%-97% of peo......MORE

Sofosbuvir/ledipasvir plus vedroprevir shows 96% response rate for hard-to-treat genotype 1 hepatitis C patients

Liz Highleyman | 2 years ago

A triple combination of Gilead Sciences' sofosbuvir/ledipasvir (Harvoni) plus the experimental HCV......MORE

Barcelona clinic study counts how many gay men might benefit from PrEP

Gus Cairns | 2 years ago

A study from the Barcelona Checkpoint gay men’s HIV clinic, presented at the recent 15th European......MORE

Sofosbuvir/velpatasvir shows high cure rates for all HCV genotypes, works well for patients with liver decompensation

Liz Highleyman | 2 years ago

A coformulation of sofosbuvir and the pan-genotypic HCV NS5A inhibitor velpatasvir from Gilead Scie......MORE

Sofosbuvir & ravidasvir delivers high sustained response rates for genotype 4 hepatitis C patients

Liz Highleyman | 2 years ago

A regimen of sofosbuvir and the pan-genotypic HCV NS5A inhibitor ravidasvir, with or without ribavi......MORE

Treatment intensification with sofosbuvir permits cure after failure of previous HCV treatment

Keith Alcorn | 2 years ago

Re-treating with an interferon-free regimen that previously failed to cure hepatitis C can result i......MORE

Almost half of US Medicaid recipients denied funding for hepatitis C treatment, 4-state study shows

Keith Alcorn | 2 years ago

Around one in six people with hepatitis C in four US states had their prescriptions for direct-acti......MORE

New AbbVie hepatitis C pan-genotypic combination cures 97% - 100% in early study

Keith Alcorn | 3 years ago

A combination of two experimental direct-acting antivirals developed by AbbVie cured 97%-100% of no......MORE

REP 2139 shows promise for people with hepatitis B and hepatitis delta co-infection

Liz Highleyman | 3 years ago

The nucleic acid-based polymer REP 2139, used first as monotherapy then combined with pegylated int......MORE

Liver cancer risk will remain elevated for people with cirrhosis cured of hepatitis C

Keith Alcorn | 3 years ago

The burden of liver cancer and cirrhosis caused by hepatitis C is likely to continue to grow in the......MORE

Sofosbuvir/velpatasvir + GS-9857 for 8 weeks cures hepatitis C for most people with genotype 1 or 3

Liz Highleyman | 3 years ago

An 8-week triple combination of Gilead Sciences' sofosbuvir, velpatasvir and GS-9857 showed a high ......MORE

HCV transmission during anal sex may happen without blood, study in HIV/HCV coinfected men finds

Keith Alcorn | 3 years ago

Hepatitis C virus is present in large enough quantities in the rectal fluid of men with HIV and hep......MORE

Grazoprevir/elbasvir shows high hepatitis C cure rate for people who inject drugs

Liz Highleyman | 3 years ago

Merck's grazoprevir/elbasvir coformulation cured hepatitis C infection in 92% of injecting drug us......MORE

People with HIV and HCV co-infection achieve high HCV cure rates with grazoprevir/elbasvir

Liz Highleyman | 3 years ago

A dual combination of Merck's grazoprevir and elbasvir taken for 12 or 16 weeks cured most HIV-posi......MORE

Women living with HIV in the UK continue to have poorer treatment outcomes

Roger Pebody | 3 years ago

Women have triple the rate of poor treatment outcomes of gay men and the gap has not narrowed over ......MORE

Ambivalence and tensions in young gay men’s accounts of monogamy and relationships

Roger Pebody | 3 years ago

Young Australian gay men’s feelings about sex and relationships are characterised by a tension be......MORE

Low CD4 count, smoking and unhealthy alcohol use are risk factors for acute exacerbation of COPD in people with HIV

Michael Carter | 3 years ago

HIV infection increases the risk of acute exacerbation of chronic obstructive pulmonary disease (AE......MORE

Truvada PrEP appears to work for transgender women, but only if used consistently

Liz Highleyman | 3 years ago

The more than 300 transgender women in the pivotal iPrEx pre-exposure prophylaxis (PrEP) trial had......MORE

Counselling for HIV sero-discordant couples associated with reductions in HIV risk behaviour

Michael Carter | 3 years ago

Counselling for HIV sero-discordant couples can achieve significant reductions in sexual risk behav......MORE

How do we maximise global HIV treatment access? IAPAC Care Continuum Guidelines make recommendations

Gus Cairns | 3 years ago

IAPAC, the International Association of Practitioners in AIDS Care, has issued a set of guidelines ......MORE

Does low-level HIV viral load raise the risk of disease progression and co-morbidities?

Liz Highleyman | 3 years ago

People living with HIV who have a detectable but low viral load – in the range of 50 to 500 or 10......MORE

Hormonal contraception safe for women with HIV and may have important health benefits

Michael Carter | 3 years ago

HIV-positive women can safely use hormonal contraception, according to research published in the on......MORE

Patients of non-specialist HIV physicians often have poor ART outcomes and frequently receive sub-optimal care

Michael Carter | 3 years ago

Physician experience is associated with the quality of care provided to HIV-positive patients, new ......MORE

Hepatitis C incidence remains stable among gay men living with HIV in Europe, but varies across countries

Liz Highleyman | 3 years ago

Researchers have seen no decline in new hepatitis C virus (HCV) infections among HIV-positive men w......MORE

Post-treatment control of HIV appears rare, biomarkers may help predict viral rebound

Liz Highleyman | 3 years ago

Only four individuals out of nearly 5000 people receiving care at US military health facilities wer......MORE

Many HIV transmissions in sero-discordant couples occuring at CD4 cell counts above ART eligibility threshold

Michael Carter | 3 years ago

Many HIV transmissions in sero-discordant couples occur when the HIV-infected partner has a high CD......MORE

Priorities for HIV care: the perspectives of healthcare providers and patients

Michael Carter | 3 years ago

Virological suppression and co-morbidities are the main focus of consultations between HIV healthca......MORE

Sofosbuvir/ledipasvir for 8 weeks cures most hard-to-treat hepatitis C patients in real-world study

Liz Highleyman | 3 years ago

Most people with hepatitis C virus (HCV) in the GECCO German hepatitis C cohort who were treated wi......MORE

Successful hepatitis C treatment lowers risk of death for people with HIV and HCV co-infection

Liz Highleyman | 3 years ago

Hepatitis C treatment that leads to sustained virological response (SVR) – generally regarded as ......MORE

Strategies for hepatitis C ‘treatment as prevention’ must address the concerns of people who inject drugs

Roger Pebody | 3 years ago

While epidemiologists and public health experts are excited by the potential of new hepatitis C dru......MORE

HIV maturation inhibitor BMS-955176 shows good safety and efficacy in phase 2a trial

Liz Highleyman | 3 years ago

Bristol-Myers Squibb’s next-generation maturation inhibitor BMS-955176 demonstrated good antivira......MORE

START sub-studies show no differences in lung or neurocognitive function with early or later treatment

Liz Highleyman | 3 years ago

Participants who started antiretroviral therapy (ART) soon after HIV diagnosis in the large START ......MORE

Community-based drug projects provide an alternative to compulsory detention in Asia

Roger Pebody | 3 years ago

A series of pilot projects in China, Indonesia and Cambodia are showing that non-coercive, communit......MORE

START sub-study shows more bone loss with earlier HIV treatment

Liz Highleyman | 3 years ago

Participants who started antiretroviral therapy (ART) soon after HIV diagnosis in the large START t......MORE

London clinic survey shows impact of chemsex on condom and PEP use

Keith Alcorn | 3 years ago

A survey of gay men in London using drugs during sex – chemsex – has shown high levels of unpro......MORE

Risk of heart attack rises with length of HIV infection, regardless of age

Keith Alcorn | 3 years ago

Ten years after becoming infected with HIV, a person living with HIV has approximately twice the ri......MORE

Harm reduction conference calls for political leadership to reform drugs policy

Roger Pebody | 3 years ago

The biggest challenges to harm reduction are drugs policy and drugs laws, the Malaysian harm reduct......MORE

Harm reduction conference calls for political leadership on drugs policy reform

Roger Pebody | 3 years ago

The biggest challenges to harm reduction are drugs policy and drugs laws, the Malaysian harm reduct......MORE

With EACS release, all international HIV treatment guidelines agree on when to start – for the first time since 2006

Gus Cairns | 3 years ago

The new European AIDS Clinical Society (EACS) HIV clinical guidelines, released last week at the 15......MORE

Tenofovir alafenamide single-tablet regimen shows good efficacy with improved kidney and bone safety

Liz Highleyman | 3 years ago

A single-tablet regimen containing the new tenofovir alafenamide (TAF) - to be marketed as Genvoya......MORE

When will Europe get PrEP?

Keith Alcorn | 3 years ago

Pressure is mounting at community level for access to pre-exposure prophylaxis (PrEP) in Europe and......MORE

Can dolutegravir dual therapy or monotherapy produce and maintain HIV suppression?

Liz Highleyman | 3 years ago

The potent integrase inhibitor dolutegravir taken with a single well-tolerated NRTI was able to ful......MORE

The majority of migrants living with HIV in Europe may have acquired HIV in their new country

Gus Cairns | 3 years ago

A study presented at the 15th European AIDS Conference yesterday found evidence that the majority o......MORE

Benefits of early HIV treatment are clear, but issues raised by START and D:A:D remain unresolved

Liz Highleyman | 3 years ago

The long-running controversy over when to start antiretroviral therapy (ART) has been definitively ......MORE

Needle and syringe exchanges need to adapt to meet the needs of people who inject steroids and image-enhancing drugs

Roger Pebody | 3 years ago

The numbers of people injecting steroids and other image-enhancing drugs has increased significantl......MORE

Newest MDR-TB drug prices could fall by up to 95% through generic production

Keith Alcorn | 3 years ago

The cost of newer drugs for the treatment of multidrug-resistant tuberculosis (MDR-TB) could be cut......MORE

TB death rate four times higher in Eastern Europe due to lack of HIV treatment after TB diagnosis

Keith Alcorn | 3 years ago

People living with HIV in Eastern Europe who develop tuberculosis (TB) are four times more likely t......MORE

Three-month isoniazid/pyrazinamide regimen prevents TB as well as 6-month isoniazid in people living with HIV

Keith Alcorn | 3 years ago

A daily three-month regimen of isoniazid and pyrazinamide is just as effective at preventing the de......MORE

Can Europe reach the 90-90-90 target for HIV treatment by 2020?

Keith Alcorn | 3 years ago

The European region needs to step up prevention and treatment activities if it is to reach the UNAI......MORE

Modest bone loss seen in young men taking Truvada for pre-exposure prophylaxis

Liz Highleyman | 3 years ago

Young men participating in a pre-exposure prophylaxis (PrEP) demonstration project experienced mode......MORE

Why is injecting equipment re-used? Drug users do their own research to find out

Roger Pebody | 3 years ago

Even in the context of the relatively good access to harm reduction services in Australia, the prin......MORE

Peer workers improve drug users’ engagement with HIV care in Ukraine

Roger Pebody | 3 years ago

An innovative programme in which peer outreach workers use a case management approach to help HIV-p......MORE

One third of people with HIV in US study are not virally suppressed on antiretroviral therapy

Liz Highleyman | 3 years ago

A third of people with HIV on antiretroviral therapy (ART) do not have sustained viral suppression ......MORE

How do we treat the world? Experts discuss moving to universal HIV treatment

Gus Cairns | 3 years ago

What practical steps does the global healthcare community need to take in order to expand HIV treat......MORE

Sofosbuvir + daclatasvir demonstrates high cure rates for people with HIV and HCV co-infection

Liz Highleyman | 3 years ago

Nearly all people with HIV and genotype 1-4 HCV co-infection treated for 12 weeks with an interfero......MORE

Retreat of international donors and neglect of national governments threatens harm reduction services

Roger Pebody | 3 years ago

The availability of needle and syringe programmes, opioid substitution therapy and other harm reduc......MORE

Emergency needle exchange in Indiana reduces HIV and HCV risk for people who inject drugs

Liz Highleyman | 3 years ago

An emergency syringe exchange program implemented after an outbreak of HIV earlier this year in the......MORE

US study provides 'real world' evidence about which patients with hepatitis C should be prioritised for therapy

Michael Carter | 3 years ago

For patients with hepatitis C virus (HCV) mono-infection, baseline fibrosis stage is strongly predi......MORE

Opioid substitution therapy, especially in combination with needle exchange, reduces transmission of hepatitis C

Roger Pebody | 3 years ago

A pooled analysis of 25 studies has shown for the first time good evidence that methadone and other......MORE

Studies continued to support tenofovir alafenamide combination pill as it nears US approval

Liz Highleyman | 3 years ago

A single-tablet regimen containing a new formulation of tenofovir maintained viral suppression for ......MORE

Hepatitis C-related mortality continues to increase in the US

Liz Highleyman | 3 years ago

Deaths related to hepatitis C virus (HCV) infection continue to rise in the US despite the advent o......MORE

At least 25,000 people in the US may now be using PrEP

Gus Cairns | 3 years ago

As many as 30,000 people in the US may now be taking pre-exposure prophylaxis to prevent HIV, the f......MORE

Abacavir/lamivudine could be driving liver damage in ART-treated patients with HIV/HCV co-infection

Michael Carter | 3 years ago

Progression of liver fibrosis among ART-treated patients with HIV/HCV co-infection is associated wi......MORE

HIV attachment inhibitor BMS-663068 matches atazanavir in phase 2b study

Liz Highleyman | 3 years ago

Bristol-Myers Squibb’s HIV attachment inhibitor BMS-663068 (fostemsavir), which prevents the viru......MORE

Interferon-free treatment works well for people who inject drugs, but barriers to access remain

Liz Highleyman | 3 years ago

Hepatitis C treatment for people who inject drugs, including those receiving opioid substitution th......MORE

Affordable Care Act coverage improves chances of viral suppression for Americans with HIV

Liz Highleyman | 3 years ago

Enrolling low-income and under-insured people with HIV in one of the new Affordable Care Act (ACA)......MORE

No transmission of integrase inhibitor-resistant HIV seen in California patients

Gus Cairns | 3 years ago

Not one case of transmission of HIV that is resistant to any of the integrase inhibitor (INI) drugs......MORE

People who inject drugs should have access to hepatitis C treatment, expert panel recommends

Keith Alcorn | 3 years ago

New recommendations on hepatitis C treatment and care for people who inject drugs encourage physici......MORE

People with HIV are at higher risk of several types of cancer, large study finds

Liz Highleyman | 3 years ago

People living with HIV remain at risk of AIDS-defining cancers in the era of effective antiretrovir......MORE

New antiretrovirals and HIV treatment strategies highlighted at ICAAC

Liz Highleyman | 3 years ago

Researchers presented findings from several HIV studies at the 55th Interscience Conference on Ant......MORE

US HIV physicians routinely offering early ART but only a third have prescribed PrEP

Michael Carter | 3 years ago

Most doctors at the frontline of the HIV epidemic in the United States recommend early antiretrovir......MORE

Recent infection and ART treatment interruptions are key periods for HIV transmission

Michael Carter | 3 years ago

A large proportion of HIV transmissions occur during recent infection or antiretroviral treatment i......MORE

New HCV NS5A inhibitor EDP-239 looks good in early studies, more evidence supports early hepatitis C treatment

Liz Highleyman | 3 years ago

A new hepatitis C virus (HCV) NS5A inhibitor being developed by Enanta – EDP-239 – was well-tol......MORE

PrEP preferences in gay men are predicted by the frequency and predictability of the sex they have

Gus Cairns | 3 years ago

A recently-published survey from the US and Canada reveals that on the whole HIV-negative gay men w......MORE

WHO guidelines recommend universal antiretroviral treatment, PrEP for those at substantial risk

Liz Highleyman | 3 years ago

The World Health Organization (WHO) released updated guidelines today calling for antiretroviral th......MORE

The enduring power of stigma – understanding why HIV-positive gay men don’t disclose their status

Roger Pebody | 3 years ago

The accounts of a group of gay men living with HIV in Dublin, most of whom rarely, if ever, disclos......MORE

High standards of care associated with reduced mortality risk of patients with HIV

Michael Carter | 3 years ago

Quality of care (QOC) in the first twelve months after entering HIV care is associated with longer-......MORE

High standards of care associated with reduced mortality risk of patients with HIV

Michael Carter | 3 years ago

Quality of care (QOC) in the first twelve months after entering HIV care is associated with longer-......MORE

Second UK cost-effectiveness study finds that large PrEP programmes may need drug price cut to be affordable

Gus Cairns | 3 years ago

A second UK cost-effectiveness study of pre-exposure prophylaxis has concluded that a medium-sized ......MORE

Substantial improvement in life expectancy of older HIV-positive patients in modern treatment era, report Danes

Michael Carter | 3 years ago

The prognosis of older HIV-positive patients has improved substantially during the era of combinati......MORE

Increasing levels of engagement with care is key to controlling HIV epidemic in US

Michael Carter | 3 years ago

“Test-and-treat” is unlikely to be an effective strategy to control the HIV epidemic in the Uni......MORE

Awareness of treatment’s impact on transmission is transforming the lives of couples of mixed HIV status

Roger Pebody | 3 years ago

A greater understanding of the impact of HIV treatment on prevention is changing the experience of ......MORE

Sexual transmission of HCV is increasing among gay and bisexual men with HIV, meta-analysis finds

Liz Highleyman | 3 years ago

Sexual transmission of hepatitis C virus (HCV) is occurring among HIV-positive men who have sex wit......MORE

Thai testing campaign suggests how local cultures can influence testing behaviour

Gus Cairns | 3 years ago

A campaign to encourage Thai gay men and other men who have sex with men (MSM) to test at least onc......MORE

Spanish pharmacy HIV testing programme detects many new infections

Gus Cairns | 3 years ago

A programme in which cheap, 30-minute HIV tests were offered in local pharmacy shops in three Spani......MORE

Cost of comprehensive global viral hepatitis prevention and treatment effort might peak at $11 billion in 2025

Keith Alcorn | 3 years ago

Reaching the World Health Organization’s (WHO) proposed targets for viral hepatitis control by 20......MORE

PROUD PrEP study results published

Gus Cairns | 3 years ago

The results of the PROUD study of HIV pre-exposure prophylaxis (PrEP) using daily tenofovir + emtri......MORE

Bone loss slows, but continues long-term in HIV-positive people on antiretroviral therapy

Liz Highleyman | 3 years ago

People with HIV experienced a decrease in bone density at the hip and spine during their first two ......MORE

Asymptomatic neurocognitive impairment in people with HIV does predict later neurocognitive symptoms

Liz Highleyman | 3 years ago

People with HIV who showed evidence of asymptomatic neurocognitive impairment at study entry were n......MORE

Rilpivirine + darunavir HIV maintenance regimen matches standard three-drug antiretroviral therapy

Liz Highleyman | 3 years ago

An NRTI-sparing dual antiretroviral regimen consisting of the NNRTI rilpivirine (Edurant) plus the ......MORE

US PrEP care cascade analysis suggests that major, structural barriers need to be addressed for PrEP to have an impact

Roger Pebody | 3 years ago

The uptake of PrEP in people who need it risks being limited due to low levels of awareness, gaps i......MORE

Medicines Patent Pool looks at hepatitis C

Keith Alcorn | 3 years ago

Greg Perry, Executive Director of the Medicines Patent Pool, told delegates at the World Hepatitis ......MORE

Oestrogen may block HIV reactivation, hints at gender differences in viral reservoirs

Liz Highleyman | 3 years ago

Oestrogen receptors on cells may play a role in HIV latency and reactivation, and drugs targeting t......MORE

Half of American gay men using dating apps have interacted with a PrEP user

Roger Pebody | 3 years ago

Almost half of American gay men recruited to a survey via advertising on a major mobile phone datin......MORE

‘Undetectable’ is both a milestone and an identity for gay men recently diagnosed with HIV

Roger Pebody | 3 years ago

Achieving an undetectable viral load is a key milestone in the period after diagnosis with HIV, qua......MORE

World Health Organization calls for ambitious global targets for viral hepatitis control

Keith Alcorn | 3 years ago

The World Health Organization (WHO) is calling for ambitious new global targets for diagnosis, trea......MORE

No HIV infections seen in San Francisco PrEP users referred via primary care

Gus Cairns | 3 years ago

A programme that provides pre-exposure prophylaxis (PrEP) through primary care referrals in San Fra......MORE

STI clinic attendees have high HIV diagnosis rates in Netherlands, but many missed opportunities in primary care

Gus Cairns | 3 years ago

Two studies from the Netherlands show that while the proportion of people with HIV who are diagnose......MORE

HIV treatment as prevention scale-up linked to reduced mortality among people who inject drugs in Vancouver

Liz Highleyman | 3 years ago

HIV-related and all-cause death decreased significantly among people who inject drugs – with sim......MORE

HIV-positive youth are less likely than adults to achieve viral suppression on antiretroviral treatment

Liz Highleyman | 3 years ago

While adolescents and young adults are about as likely as older people to be linked to care after b......MORE

Fatty liver may contribute to higher risk of death for HIV/HCV co-infected people

Liz Highleyman | 3 years ago

About a quarter of people in a New York City cohort who had HIV and hepatitis C virus (HCV) died ov......MORE

Good outcomes for people living with HIV diagnosed with Hodgkin's lymphoma in France

Michael Carter | 3 years ago

People living with HIV who are diagnosed with Hodgkin’s lymphoma now have excellent outcomes, Fre......MORE

HCV infection associated with hardening of the coronary artery

Michael Carter | 3 years ago

Chronic hepatitis C virus (HCV) infection is associated with an important early warning side of car......MORE

HIV-treatment 'booster drugs' are most likely to have dangerous interactions with methamphetamine, mephedrone, MDMA and ketamine

Roger Pebody | 3 years ago

The two drugs involved in HIV treatment that are most likely to have dangerous interactions with re......MORE

Ugandan gay men talk about why they do not always use condoms

Gus Cairns | 3 years ago

Gay men and other men who have sex with men (MSM) in Uganda, who had not used a condom last time th......MORE

HIV-positive postpartum women who rapidly re-engage with HIV care more likely to have viral suppression in longer term

Michael Carter | 3 years ago

HIV-positive women who have recently given birth have low rates of engagement with HIV care, invest......MORE

Low rates of engagement with HIV care among women who have recently given birth in Cape Town townships

Michael Carter | 3 years ago

Only half of HIV-positive mothers in townships near Cape Town, South Africa, who received antenatal......MORE

People with HIV and hepatitis B co-infection can safely switch to simpler TAF single-tablet regimen

Liz Highleyman | 3 years ago

People with HIV and hepatitis B virus (HBV) co-infection maintained HIV viral suppression, maintain......MORE

Hepatitis C cure associated with significant improvement in liver stiffness in people with HIV and HCV co-infection

Michael Carter | 3 years ago

A successful response to hepatitis C virus (HCV) therapy is associated with a significant improveme......MORE

People with hepatitis B can safely use Truvada PrEP for HIV prevention

Liz Highleyman | 3 years ago

People with hepatitis B virus (HBV) infection did not experience liver inflammation 'flares' or oth......MORE

Study sheds light on how tenofovir is processed in different body tissues

Liz Highleyman | 3 years ago

Tenofovir, which is widely used for HIV treatment and prevention, is activated in a tissue-specific......MORE

Third of people with HIV who use drugs intentionally miss doses of HIV treatment when planning to use drugs

Michael Carter | 3 years ago

Beliefs about possible toxic interactions between antiretroviral therapy (ART) and illicit drugs ar......MORE

Low-threshold methadone maintenance reduces HIV risk for people who inject drugs

Keith Alcorn | 3 years ago

Receiving methadone maintenance therapy through primary care physicians or community pharmacies sig......MORE

First Brazilian PrEP data reinforce evidence that PrEP is most used by those at greatest risk

Gus Cairns | 3 years ago

The first data from a Brazilian open-label demonstration project of HIV pre-exposure prophylaxis (P......MORE

Cirrhosis and decompensation are common among people with chronic hepatitis C

Liz Highleyman | 3 years ago

More than one-quarter of people with chronic hepatitis C at Kaiser-Permanente developed liver cirrh......MORE

Indiana HIV outbreak offers lessons about containing local outbreaks and need for harm reduction

Liz Highleyman | 3 years ago

An early-2015 outbreak of HIV and hepatitis C virus (HCV) in rural Indiana, USA, linked to injectio......MORE

Starting ART reduces TB risk for HIV-positive patients in South Africa

Michael Carter | 3 years ago

Starting antiretroviral therapy (ART) significantly reduces the risk of tuberculosis (TB) for patie......MORE

WAVES shows elvitegravir regimen beats boosted atazanavir for women with HIV

Liz Highleyman | 3 years ago

A study of antiretroviral treatment specifically for women with HIV showed that a single-tablet reg......MORE

Open-label PrEP in Botswana: very high adherence and no HIV infections seen

Gus Cairns | 3 years ago

A study of open-label Truvada HIV pre-exposure prophylaxis (PrEP) in Botswana among heterosexual pe......MORE

Peer or community interventions improve outcomes for mothers with HIV

Carole Leach-Lemens | 3 years ago

Peer- and community-based interventions can significantly increase retention in care of mothers wit......MORE

Retention in pre-ART care can be boosted by monthly visits from volunteer support workers

Michael Carter | 3 years ago

Retention in HIV care for patients not eligible for antiretroviral therapy (ART) can be boosted by ......MORE

Daclatasvir plus sofosbuvir cures HCV for most people with HIV and HCV co-infection in French compassionate use programme

Liz Highleyman | 3 years ago

Interferon-free treatment using daclatasvir (Daklinza) and sofosbuvir (Sovaldi), with or without ri......MORE

Interferon-free hepatitis treatment is highly effective for people with HIV and HCV co-infection in three studies

Liz Highleyman | 3 years ago

Three different interferon-free regimens – sofosbuvir/ledipasvir, AbbVie's 3D regimen and grazopr......MORE

Intensification of antiretroviral therapy reduces risk of late-term mother-to-child HIV transmission

Carole Leach-Lemens | 3 years ago

Maternal and infant antiretroviral therapy (ART) intensification is very effective in preventing HI......MORE

Implant and injectable hormonal contraception most effective methods for women living with HIV

Carole Leach-Lemens | 3 years ago

Hormonal contraceptive methods are highly effective in reducing the risk of pregnancy in women livi......MORE

Liver fibrosis regression after hepatitis C treatment linked to reduced complications and death in people with HIV and HCV co-infection

Liz Highleyman | 3 years ago

People with HIV and HCV co-infection, with liver cirrhosis, who achieve sustained virological respo......MORE

Switching to new tenofovir alafenamide keeps virus in check and improves kidney and bone health

Liz Highleyman | 3 years ago

People who switch from the current version of tenofovir to tenofovir alafenamide (TAF) – a new fo......MORE

Raltegravir appears to prevent mother-to-child HIV transmission during late pregnancy

Liz Highleyman | 3 years ago

Combination antiretroviral therapy containing the integrase inhibitor raltegravir (Isentress) appea......MORE

PrEP demo project finds the people at highest HIV risk generally take PrEP most consistently

Gus Cairns | 3 years ago

An open-label demonstration project of Truvada pre-exposure prophylaxis (PrEP) in the United States......MORE

Vancouver's treatment as prevention success is also due to harm reduction and addiction treatment

Roger Pebody | 3 years ago

“We talk a lot about the success of treatment as prevention in Vancouver, but we always need to m......MORE

HIV self-testing may help the 'hard to reach' learn their status, but uncertainties remain

Roger Pebody | 3 years ago

HIV self-testing (or ‘home testing’) is likely to have an important place in future global HIV ......MORE

Peer-led network intervention substantially lowers HIV infections in people who use drugs in Ukraine

Roger Pebody | 3 years ago

A cluster randomised trial in Ukraine has shown that a peer education project reduced new HIV infec......MORE

Gay youth PrEP study finds good retention and reasonable adherence

Gus Cairns | 3 years ago

A US study of pre-exposure prophylaxis in 200 young gay and bisexual men aged 18-22 found reasonabl......MORE

Giving people information about HIV treatment as prevention lessens stigma and increases testing rates

Roger Pebody | 3 years ago

A large randomised trial of communities in rural Malawi shows that a single community meeting provi......MORE

New NNRTI doravirine suppresses HIV as well as efavirenz but with fewer central nervous system side-effects

Liz Highleyman | 3 years ago

Merck's next-generation NNRTI doravirine (formerly known as MK-1439) was found to be as effective ......MORE

Same-day start to antiretroviral treatment leads to faster HIV suppression in San Francisco

Liz Highleyman | 3 years ago

A programme at San Francisco General Hospital that offers antiretroviral therapy (ART) on the same......MORE

Opioid substitution therapy combined with HIV treatment saves the lives of more drug users than ART alone

Keith Alcorn | 3 years ago

Providing opioid substitution therapy (OST) alongside antiretroviral therapy (ART) to people who in......MORE

Younger gay men have much lower risk of acquiring HIV than previous generations, but racial disparities persist

Roger Pebody | 3 years ago

An innovative analysis of HIV trends in the Seattle area has found that gay men who were born in th......MORE

Half of African migrants diagnosed with HIV in France acquired HIV while living there

Roger Pebody | 3 years ago

Between a third and a half of African people living with HIV in France probably acquired HIV after ......MORE

Next-generation maturation inhibitor BMS-955176 shows good antiviral activity in combination with atazanavir

Liz Highleyman | 3 years ago

The next-generation HIV maturation inhibitor BMS-955176 was well-tolerated and suppressed HIV viral......MORE

Intermittent PrEP may be a robust strategy for anal sex – vaginal much less certain

Gus Cairns | 3 years ago

The pharmacodynamics (drug absorption and elimination rates) of the two drugs that comprise Truvada......MORE

‘Nuanced’ sero-adaptive behaviours being used by Australian and American gay men

Roger Pebody | 3 years ago

There is evidence that some groups of Australian and American gay men are considering HIV-positive ......MORE

'Nuanced' sero-adaptive behaviours being used by Australian and American gay men

Roger Pebody | 3 years ago

There is evidence that some groups of Australian and American gay men are considering HIV-positive ......MORE

Treatment cascades show 90-90-90 goal within reach for some - but Eastern Europe lags behind Africa

Keith Alcorn | 3 years ago

Global analysis of HIV treatment cascades – the proportions of people diagnosed with HIV, in care......MORE

Treatment cascades show 90-90-90 goal within reach for some – but Eastern Europe lags behind Africa

Keith Alcorn | 3 years ago

Global analysis of HIV treatment cascades – the proportions of people diagnosed with HIV, in care......MORE

The Pros and Cons of PrEP: trial volunteers recount their experience of the ADAPT study

Gus Cairns | 3 years ago

The reasons whether or not people come forward for pre-exposure prophylaxis (PrEP) or take it once ......MORE

Cash compensation encourages uptake of circumcision, PMTCT services

Keith Alcorn | 3 years ago

Cash compensation can improve the uptake of key HIV prevention services in sub-Saharan Africa, res......MORE

Active invitation and tracing more likely to get men involved in couples HIV counselling and testing

Carole Leach-Lemens | 3 years ago

Active invitation and tracing of male partners of pregnant women newly diagnosed with HIV substanti......MORE

Cash to stay in school doesn’t reduce HIV incidence in South African study – but school attendance protected young women against HIV

Keith Alcorn | 3 years ago

A conditional cash transfer to the households of adolescent girls to promote school attendance did ......MORE

START trial provides definitive evidence of the benefits of early HIV treatment

Liz Highleyman | 3 years ago

People who start antiretroviral therapy (ART) immediately after HIV diagnosis, while their CD4 cell......MORE

Innovative approaches to linkage to care boost clinic visits, HIV treatment uptake in African study

Keith Alcorn | 3 years ago

A systematic effort to promote HIV testing, linkage to care for people diagnosed with HIV and circu......MORE

Non-daily PrEP regimens provide extra options, but adherence is often better with daily dosing

Roger Pebody | 3 years ago

For some people in some settings, less frequent PrEP regimens with doses linked to sexual activity ......MORE

Targets proliferate in HIV cure research

Gus Cairns | 3 years ago

The Towards an HIV Cure two-day symposium has become a fixture in advance of the International AIDS......MORE

No HIV infections from partners with fully suppressed viral load during long-term follow up of landmark treatment as prevention trial

Keith Alcorn | 3 years ago

Final follow up of the HPTN 052 study of treatment as prevention shows no evidence of HIV transmiss......MORE

Young woman stays undetectable for twelve years off treatment after early HIV therapy

Gus Cairns | 3 years ago

The 8th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 20......MORE

Presumptive treatment of TB in advanced HIV no better than giving ART and isoniazid

Keith Alcorn | 3 years ago

Giving treatment for tuberculosis to all people with very advanced HIV disease at the time they sta......MORE

Access to screening and treatment are key issues for hepatitis B and C and HIV/viral hepatitis co-infection

Liz Highleyman | 3 years ago

The development of effective new interferon-free treatment makes it possible to cure more than 90% ......MORE

Vancouver Consensus statement calls for early access to treatment and PrEP worldwide

Keith Alcorn | 3 years ago

Leading figures in the HIV response have endorsed a call for immediate access to antiretroviral the......MORE

World Health Organization urges more HIV testing by non-medical staff, outside of clinical settings, targeted to those who need it the most

Roger Pebody | 3 years ago

In addition to recommending that routine HIV testing in medical settings be expanded to reach new g......MORE

World Health Organization to recommend HIV treatment for all

Keith Alcorn | 3 years ago

The World Health Organization will issue new HIV treatment guidelines later this year recommending ......MORE

Test and treat studies and African countries showing that 90-90-90 targets are achievable

Roger Pebody | 3 years ago

Health services in some African countries including Botswana, Rwanda and Malawi are now providing e......MORE

Reaching UNAIDS HIV treatment targets could avert millions of deaths and new infections

Liz Highleyman | 3 years ago

Achieving UNAIDS 90-90-90 targets for getting more people with HIV diagnosed and on antiretroviral ......MORE

New drug holds out promise of long-term control or even cure of HIV

Gus Cairns | 3 years ago

Scientists at the Scripps Research Institute in California have discovered a new type of drug that ......MORE

HIV PEP with emtricitabine/tenofovir/rilpivirine has excellent completion and adherence rates

Michael Carter | 3 years ago

Daily post-exposure prophylaxis (PEP) with single tablet emtricitabine/tenofovir/rilpivirine (Compl......MORE

HIV-positive patients in Africa do well on three second-line ART regimens

Michael Carter | 3 years ago

Three second-line antiretroviral therapy (ART) regimens are equally safe and effective for patients......MORE

South Africa: Women of lower socio-economic status have greater needs for services to prevent mother-to-child HIV transmission

Lesley Odendal | 3 years ago

Pregnant women of lower socio-economic status are more likely to take up early HIV testing and to h......MORE

One step further towards an HIV vaccine: and this one performed as expected

Gus Cairns | 3 years ago

A recent experimental HIV vaccine protected 50% of a group of twelve rhesus monkeys from infection ......MORE

Second-line ART patients reach viral re-suppression following intensified adherence support

Lesley Odendal | 3 years ago

Sixty-seven per cent of all patients who were failing second-line ART achieved viral re-suppressio......MORE

Black market for Truvada PrEP may undermine treatment adherence in marginalised people living with HIV

Roger Pebody | 3 years ago

The increasing demand for pre-exposure prophylaxis (PrEP) is likely to increase the likelihood that......MORE

Community-based adherence clubs show high retention in HIV care and treatment adherence

Lesley Odendal | 3 years ago

People with HIV who were receiving their HIV treatment outside of health facilities in community-ba......MORE

Nurse-led palliative care can be successfully integrated into routine HIV services in Kenya

Michael Carter | 3 years ago

Integrating nurse-led palliative care into routine HIV services has positive effects for the psycho......MORE

Prompt ART especially important for people with HIV aged 45 and over

Michael Carter | 3 years ago

Delaying antiretroviral therapy (ART) may have especially serious consequences for middle-aged and ......MORE

Longer secondary education protects against HIV infection, Botswana study shows

Keith Alcorn | 3 years ago

Every additional year of schooling among young people in Botswana was associated with an 8% reducti......MORE

Where next in PrEP and microbicides? Europeans discuss research pipeline

Gus Cairns | 3 years ago

Thursday 18 June saw the final research meeting in Brussels of CHAARM (Combined Highly Active Anti-......MORE

ART roll-out in Uganda accompanied by increased rates of HIV disclosure to spouses

Michael Carter | 3 years ago

Roll-out of antiretroviral treatment (ART) has been accompanied by an increase in the proportion of......MORE

Multiple strategies for safer conception need to incorporate couples' preferences

Lesley Odendal | 3 years ago

Misunderstandings about serodiscordance and limited understanding of female fertility and male inse......MORE

Unmet basic needs may be related to poor rates of durable viral suppression among transgender women with HIV

Michael Carter | 3 years ago

Transgender women living with HIV are less likely to have excellent adherence to antiretroviral tre......MORE

People with HIV and HCV co-infection who have fibrosis stages F2 and above should be prioritised for new anti-HCV therapies

Michael Carter | 3 years ago

People with HIV and hepatitis C virus (HCV) co-infection who have advanced liver fibrosis should be......MORE

South Africa: Lower coverage of maternal HIV testing among adolescents leading to higher mother-to-child transmission

Lesley Odendal | 3 years ago

Adolescents have lower coverage of HIV testing and subsequent prevention of mother-to-child (PMTCT)......MORE

South Africa: Lower coverage of maternal HIV testing among adoelscents leading to higher mother-to-child transmission

Keith Alcorn | 3 years ago

Adolescents have lower coverage of HIV testing and subsequent prevention of mother-to-child (PMTCT)......MORE

HIV stigma decreases with scale-up of HIV treatment

Roger Pebody | 3 years ago

In high-prevalence countries of sub-Saharan Africa, the scale-up of HIV treatment appears to have r......MORE

Liver transplants in HIV/HCV co-infection: study underlines importance of hepatitis C treatment

Keith Alcorn | 3 years ago

People with HIV and hepatitis C co-infection were significantly more likely to experience organ re......MORE

New British guidelines recommend treatment for everyone with HIV

Keith Alcorn | 3 years ago

Everyone with HIV who is prepared to take antiretroviral treatment should receive it, regardless of......MORE

Four in ten people diagnosed with HIV in Europe are migrants

Gus Cairns | 3 years ago

Nearly four out of every ten people with HIV in the European Economic Area (EEA) is a migrant to th......MORE

Not having enough food linked to poor treatment outcomes in New York

Roger Pebody | 3 years ago

People who don’t have enough food to eat are less likely to have an undetectable viral load than ......MORE

Living in a stigmatizing country increases HIV risk for MSM in Europe

Michael Carter | 3 years ago

Men who have sex with men (MSM) living in European countries with laws and attitudes that stigmatiz......MORE

Vaginal microbicide ring study releases first data on participants

Gus Cairns | 3 years ago

An efficacy study of a new method of HIV prevention has published its first data. ASPIRE is one of ......MORE

Liver function and survival improve after treatment with Viekirax + Exviera regimen

Liz Highleyman | 3 years ago

Hepatitis C patients treated with AbbVie's Viekirax plus Exviera or '3D' regimen saw improvements i......MORE

Geriatric conditions common in middle-aged and older HIV-positive men

Michael Carter | 3 years ago

Geriatric conditions were common in middle-aged and older HIV-positive adults in a San Francisco cl......MORE

Geriatric HIV: living with multiple medical conditions will become the norm as population ages

Roger Pebody | 3 years ago

In fifteen years time, the clinical needs of Dutch people living with HIV will have changed substan......MORE

Consider cannabis use when assessing middle-aged and older patients with HIV, say US investigators

Michael Carter | 3 years ago

Recent cannabis (marijuana) use by middle-aged HIV-positive adults is associated with poor mental h......MORE

High HCV infection rate in sub-Saharan Africa, with prevalence especially high in patients with HIV

Michael Carter | 3 years ago

Prevalence of hepatitis C virus (HCV) infection is high in sub-Saharan Africa, according to a repor......MORE

Acute HCV infections observed among HIV-negative gay men in London

Michael Carter | 3 years ago

Hepatitis C virus (HCV) infections are occurring among HIV-negative gay men in London, investigator......MORE

Most gay men with HIV in central European capitals are undiagnosed, survey has found

Gus Cairns | 3 years ago

A survey of gay men in the European cities of Barcelona, Bratislava, Bucharest, Ljubljana, Prague a......MORE

Hepatitis B and C co-infection linked to worse liver fibrosis than hepatitis B alone

Liz Highleyman | 3 years ago

People with both hepatitis B virus (HBV) and hepatitis C virus (HCV) co-infection may experience mo......MORE

Hepatitis C treatment could halve HCV transmission among gay men in UK over 10 years

Keith Alcorn | 3 years ago

Access to more effective hepatitis C treatment could halve new infections among men who have sex wi......MORE

Reinfection after hepatitis C cure: prevention may require long-term support for people who have injected drugs

Keith Alcorn | 3 years ago

Reinfection rates after hepatitis C cure among people who inject drug users, as well as past drug u......MORE

Sofosbuvir plus daclatasvir for 12 weeks cures most HIV/HCV coinfected patients

Liz Highleyman | 3 years ago

Nearly all HIV/HCV coinfected patients treated for 12 weeks with an interferon- and ribavirin-free ......MORE

Transmitted HIV drug resistance is persistent but is not harming treatment responses in the UK

Gus Cairns | 3 years ago

A study that looks at the genetic makeup of archived samples of drug-resistant HIV in the UK has fo......MORE

Depression strongly associated with risky sex in UK gay men

Roger Pebody | 3 years ago

HIV-negative gay men who have several symptoms of depression are more likely to report sex without ......MORE

Provision of PrEP in the UK will be cost-effective for gay men at high risk of HIV, model finds

Gus Cairns | 3 years ago

A cost-effectiveness model of HIV pre-exposure prophylaxis (PrEP) for gay men based on the data fro......MORE

Many South African women become infected with HIV during pregnancy posing high risk of transmission to their infants

Michael Carter | 3 years ago

There is a high risk of HIV seroconversion during pregnancy for women in South Africa, investigator......MORE

Harm reduction for people who inject drugs in New York has worked, but hasn’t reduced racial inequality

Gus Cairns | 3 years ago

Needle and syringe exchange and opiate substitution therapy in New York City has worked in reducing......MORE

START trial finds that early treatment improves outcomes for people with HIV

Gus Cairns | 3 years ago

A major international randomised clinical trial has found that people living with HIV have a consid......MORE

High lifetime costs of treating HIV show importance of investing in prevention

Michael Carter | 3 years ago

The lifetime cost for treating one HIV infection in the UK is almost £380,000, according to a mode......MORE

Acute HIV infection may present in many ways – sometimes as a serious illness

Gus Cairns | 3 years ago

A Swiss study of people who were diagnosed during early HIV infection has found that a quarter of t......MORE

Funders' priorities and targets hindered community mobilisation and meaningful participation of sex workers in India

Roger Pebody | 3 years ago

Two qualitative studies, investigating the implementation of a massive programme of HIV prevention ......MORE

Lower daily tenofovir dose of 150mg safe and effective in people with moderate renal impairment

Michael Carter | 3 years ago

A reduced tenofovir (Viread) dose of 150mg daily appears to be a safe and effective treatment for p......MORE

Hepatitis C treatment for people in prison may be highly cost-effective in England

Keith Alcorn | 3 years ago

Reducing the duration of direct-acting antiviral treatment for hepatitis C will make treatment for ......MORE

Prioritisation is crucial for the success of PrEP, model confirms

Gus Cairns | 3 years ago

A mathematical model developed by two researchers at Imperial College in London, and based on what ......MORE

Statin use associated with lower risk of liver decompensation and death in hepatitis C patients with cirrhosis

Liz Highleyman | 3 years ago

Hepatitis C patients with liver cirrhosis were significantly less likely to progress to decompensat......MORE

Inter-connecting health problems increase HIV risk for MSM

Michael Carter | 3 years ago

Intertwining health problems – syndemics -  are associated with higher viral load and poorer adh......MORE

Civacir immune globulin may help prevent HCV reinfection after liver transplant

Liz Highleyman | 3 years ago

Civacir, a hepatitis C immune globulin or antibody product, reduced the likelihood of hepatitis C v......MORE

Gilead triple combination cures easy-to-treat hepatitis C patients in 6 weeks, but 4 weeks is not enough

Liz Highleyman | 3 years ago

A 6-week regimen of sofosbuvir (Sovaldi) plus two experimental direct-acting antivirals being devel......MORE

Shortening hepatitis C treatment to 6 weeks effective but not perfect for easier-to-treat patients

Keith Alcorn | 3 years ago

Shortening hepatitis C treatment to 6 weeks for easier-to-treat patients without cirrhosis does not......MORE

Truvada PrEP causes only mild loss of bone mineral density

Michael Carter | 3 years ago

Treatment with tenofovir/emtricitabine (Truvada) as pre-exposure prophylaxis (PrEP) is associated w......MORE

People with hepatitis C have higher cancer rates, even when excluding liver cancer

Liz Highleyman | 3 years ago

Hepatitis C patients in the Kaiser Permanente Southern California health maintenance organization h......MORE

Modern NNRTI regimens can be effective with 85% adherence

Michael Carter | 3 years ago

Some modern HIV treatment regimens can achieve viral suppression with adherence rates as low as 85%......MORE

Modern NNRTI regimens can be effective with 85% adherence

Michael Carter | 3 years ago

Some modern HIV treatment regimens can achieve viral suppression with adherence rates as low as 85%......MORE

Sofosbuvir-based therapy effective for hepatitis C patients with decompensated cirrhosis

Liz Highleyman | 3 years ago

Interferon-free regimens containing sofosbuvir (Sovaldi) plus simeprevir (Olysio) cured about three......MORE

Five antiretroviral combinations associated with increased risk of a cardiovascular event

Michael Carter | 3 years ago

Treatment with four individual and five combinations of anti-HIV drugs is associated with an increa......MORE

Gilead triple combination cures easy-to-treat hepatitis C patients in 6 weeks, but 4 weeks is not enough

Liz Highleyman | 3 years ago

A 6-week regimen of sofosbuvir (Sovaldi) plus two experimental direct-acting antivirals being devel......MORE

HIV infection and low CD4 count associated with hardening of arteries

Michael Carter | 3 years ago

HIV infection is associated with an increased risk of hardening of the arteries, investigators repo......MORE

Another study confirms detrimental effects of delaying hepatitis C treatment

Liz Highleyman | 3 years ago

Deferring antiviral therapy for hepatitis C until a person progresses to advanced liver disease has......MORE

When a short course of sofosbuvir/ledipasvir fails, some people can be cured of hepatitis C with a double treatment duration

Liz Highleyman | 3 years ago

More than 70% of people with chronic genotype 1 hepatitis C who did not achieve a sustained virolog......MORE

People who don’t tell anyone else their HIV status have as good health outcomes as other people living with HIV

Roger Pebody | 3 years ago

A large survey of people attending HIV clinics in the UK has found that those individuals who chose......MORE

Many undiagnosed HIV infections picked up when testing people who have other medical conditions, but implementation challenges remain

Roger Pebody | 3 years ago

A Europe-wide project offering HIV tests to hospital patients with glandular fever symptoms, swolle......MORE

Sofosbuvir-based treatment safe and effective in advanced kidney disease

Keith Alcorn | 3 years ago

Sofosbuvir-based direct-acting antiviral therapy for hepatitis C can be used safely and effectively......MORE

Merck's grazoprevir/elbasvir combo cures 99% of hepatitis C in chronic kidney disease

Keith Alcorn | 3 years ago

The once-daily combination of grazoprevir and elbasvir cured hepatitis C in 99% of people with adva......MORE

Sofosbuvir plus pegylated interferon/ribavirin is highly effective for people with hard-to-treat genotype 3 hepatitis C

Liz Highleyman | 3 years ago

A throwback regimen of sofosbuvir (Sovaldi), ribavirin and pegylated interferon taken for 12 weeks ......MORE

Sofosbuvir, daclatasvir and ribavirin cures hepatitis C for most people with advanced cirrhosis or liver transplants

Liz Highleyman | 3 years ago

An interferon-free regimen of sofosbuvir, daclatasvir and ribavirin for 12 weeks produced sustained......MORE

New EASL guidelines prioritise interferon-free hepatitis C treatment

Liz Highleyman | 3 years ago

The European Association for the Study of the Liver (EASL) released its latest hepatitis C treatmen......MORE

Alcohol misuse the strongest predictor of severe liver damage and death in French people with hepatitis C

Keith Alcorn | 3 years ago

People with hepatitis C have a much greater risk of liver-related hospitalisation or death if they ......MORE

Expanded vaccination and treatment could help eliminate hepatitis B worldwide

Liz Highleyman | 3 years ago

While universal infant hepatitis B virus (HBV) vaccination has already led to major advances in red......MORE

Grazoprevir/elbasvir highly effective in treatment-experienced a nd HIV-coinfected hepatitis C patients

Keith Alcorn | 3 years ago

The combination of grazoprevir and elbasvir without ribavirin is highly effective in curing hepati......MORE

Advanced liver damage is common in people with undiagnosed hepatitis C in US survey

Keith Alcorn | 3 years ago

  Around one in five of people with hepatitis C in the United States who do not know of their inf......MORE

Grazoprevir/elbasvir highly effective in treatment-experienced and HIV-coinfected hepatitis C patients

Keith Alcorn | 3 years ago

The combination of grazoprevir and elbasvir without ribavirin is highly effective in curing hepatit......MORE

First HIV home test approved for sale in UK

Roger Pebody | 3 years ago

The BioSure HIV Self Test, designed to be used by untrained users at home was granted a CE mark yes......MORE

Many people living with HIV willing to take part in cure research, despite its risks

Roger Pebody | 3 years ago

There is a strong interest among people living with HIV in studies towards an HIV cure, with many p......MORE

Grazoprevir / elbasvir highly effective in previously untreated hepatitis C

Keith Alcorn | 3 years ago

A 12-week course of the combination of grazoprevir and elbasvir cured 95% of previously untreated p......MORE

Men taking HIV treatment have undetectable viral loads in the rectum; sexually transmitted infections make no difference

Roger Pebody | 3 years ago

A small study assessing the infectiousness of HIV-positive gay men taking antiretroviral therapy ha......MORE

Sofosbuvir/ledipasvir plus ribavirin shows high cure rate for hepatitis C patients with advanced liver disease

Liz Highleyman | 3 years ago

An oral regimen of sofosbuvir/ledipasvir (Harvoni) and ribavirin taken for 12 or 24 weeks produced ......MORE

Merck HCV combination effective after failure of first generation of direct-acting antivirals

Keith Alcorn | 3 years ago

A 12-week course of treatment with two direct-acting antivirals in development by Merck  plus riba......MORE

Merck HCV combination achieves 90% cure in advanced cirrhosis

Keith Alcorn | 3 years ago

A 12-week course of treatment with two direct-acting antivirals in development by Merck cured hepat......MORE

Treatment outcomes no better with single tablet regimens than individual tablets

Roger Pebody | 3 years ago

One pill a day HIV treatments such as Atripla, Stribild and Eviplera have the same rates of virolog......MORE

HCV viral load levels during treatment and speed of decline do not predict cure with interferon-free therapy

Liz Highleyman | 3 years ago

Direct-acting antiviral regimens containing sofosbuvir (Sovaldi) and the drugs in Viekirax/Exviera ......MORE

Daily PrEP leads to better adherence and protective drug levels in women

Liz Highleyman | 3 years ago

HIV-negative African women assigned to take once-daily Truvada for HIV pre-exposure prophylaxis (Pr......MORE

High treatment failure rate among Thai children switching to second-line ART

Michael Carter | 3 years ago

There is a high treatment failure rate among children taking second-line antiretroviral therapy (AR......MORE

Annual CD4 count monitoring may be sufficient for people doing well on HIV treatment

Michael Carter | 3 years ago

Annual CD4 count monitoring may be sufficient for people taking antiretroviral treatment who have a......MORE

Newly adopted risk behaviours predict HIV infections in Portuguese gay men

Roger Pebody | 3 years ago

Changes to an individual’s risk profile – including starting to have unprotected sex with a ste......MORE

High-dose rifampicin may shorten time to TB clearance

Liz Highleyman | 3 years ago

A combination regimen containing high-dose rifampicin (also known as rifampin) was associated with ......MORE

Women in PrEP trial feared they would have to leave study if they reported low adherence

Gus Cairns | 3 years ago

Post-study interviews and computer questionnaires conducted with former participants in a trial of ......MORE

Opioid substitution treatment increases chances that people who inject drugs will have good adherence to HIV therapy

Michael Carter | 3 years ago

Opioid substitution treatment (OST) increases the chances of people who inject drugs achieving good......MORE

Global hepatitis B epidemic treatable at cost of just $36 per patient per year

Michael Carter | 3 years ago

Large-scale production of generic entecavir could cut the cost of first-line hepatitis B virus (HBV......MORE

Six in ten US HIV infections are transmitted by people who know they have HIV but are not in care

Gus Cairns | 3 years ago

The majority of HIV in the USA is transmitted by people who know they have HIV but are not in care,......MORE

End-stage liver disease is a concern for people with HIV and hepatitis B or C co-infection

Liz Highleyman | 3 years ago

People with HIV and hepatitis B or C virus co-infection are more likely to progress to end-stage li......MORE

Ritonavir concentrations not correlated with lipid levels in people with HIV taking boosted atazanavir or boosted darunavir

Michael Carter | 3 years ago

People taking HIV treatment based on ritonavir-boosted atazanavir and darunavir have comparable lon......MORE

Cannabis use reduces risk of insulin resistance in people with HIV/HCV co-infection

Michael Carter | 3 years ago

Cannabis use is associated with a reduced risk of insulin resistance in people with HIV and hepatit......MORE

Chinese study sheds light on how well treatment may work as prevention in the real world

Gus Cairns | 3 years ago

A study from the Henan province of China published recently shows that antiretroviral therapy (ART)......MORE

HCV sexual transmission linked to anal sex, drug use, lower CD4 count

Liz Highleyman | 3 years ago

In addition to the usual risk factors for hepatitis C virus (HCV) sexual transmission seen in most ......MORE

Most HIV-positive gay men in European survey are on HIV treatment, though fewer in the east

Gus Cairns | 3 years ago

The large EMIS survey of gay men living in Europe has found that over 70% of respondents with HIV a......MORE

More people in the UK are starting HIV treatment early, in order to reduce their risk of transmission

Roger Pebody | 3 years ago

There is evidence of increasing interest in HIV treatment as prevention among people living with HI......MORE

Adherence support improves ART outcomes in Kenya

Michael Carter | 3 years ago

The scale-up of antiretroviral therapy (ART) in Kenya is being undermined by high rates of treatmen......MORE

Early antiretroviral treatment reduces, but does not eliminate HIV reservoir

Liz Highleyman | 3 years ago

Starting antiretroviral therapy (ART) very soon after infection may limit the size of the HIV 'rese......MORE

Experimental agents reverse HIV latency and help immune system fight HIV-infected cells

Liz Highleyman | 3 years ago

Researchers at the recent Conference on Retroviruses and Opportunistic Infections (CROI 2015) in S......MORE

Screening for cryptococcal meningitis and adherence support reduce mortality among people starting ART in Africa

Michael Carter | 3 years ago

Screening and treatment for cryptococcal meningitis combined with a short period of adherence suppo......MORE

Good mental health associated with excellent adherence among people taking ART for prevention

Michael Carter | 3 years ago

Good mental health was the only significant factor associated with optimal pill-taking among people......MORE

Canada: PrEP use now could save considerable sums in the future

Gus Cairns | 3 years ago

A Canadian paper that weighs the cost of using pre-exposure prophylaxis (PrEP) to prevent HIV infec......MORE

Cabotegravir and rilpivirine effective for HIV maintenance therapy at 96 weeks

Liz Highleyman | 3 years ago

An combination of two once-daily oral antiretrovirals – the next-generation integrase inhibitor c......MORE

FRAX fracture prediction tool underestimates fracture risk in people with HIV

Theo Smart | 3 years ago

The Fracture Risk Assessment Tool (FRAX), an online tool developed by the World Health Organization......MORE

Sustained virological response represents a long-term cure for people with hepatitis C treated with sofosbuvir

Liz Highleyman | 3 years ago

Almost all patients with hepatitis C virus alone or HIV/HCV coinfection who achieved sustained viro......MORE

Inflammation and gut leakage remains elevated in people with HIV despite early antiretroviral treatment

Liz Highleyman | 3 years ago

Inflammatory changes and damage to the gut begin very soon after initial HIV infection, and may not......MORE

Screening may miss pre-cancerous anal lesions in women with HIV

Theo Smart | 3 years ago

Existing algorithms to screen for anal cancer in women living with HIV could be missing many cases ......MORE

Re-infection due to ongoing risk probably the cause of HCV recurrence after SVR

Michael Carter | 3 years ago

Rates of hepatitis C virus (HCV) reoccurrence after successful therapy differ markedly between risk......MORE

Sofosbuvir/ledipasvir raises some antiretroviral levels in HIV/HCV coinfected people

Keith Alcorn | 3 years ago

HIV/HCV coinfected people who take sofosbuvir/ledipasvir (Harvoni) to treat hepatitis C along with ......MORE

Sofosbuvir/ledipasvir raises some antiretroviral levels in HIV/HCV coinfected people

Liz Highleyman | 3 years ago

HIV/HCV coinfected people who take sofosbuvir/ledipasvir (Harvoni) to treat hepatitis C along with ......MORE

Studies offer mounting evidence that statins may reduce the risk of heart disease in people living with HIV

Theo Smart | 3 years ago

Evidence is mounting that statin therapy can prevent the progression of coronary atherosclerosis (......MORE

We may need to combine many approaches to achieve a cure, delegates hear

Gus Cairns | 3 years ago

It is unlikely that one single approach will achieve a cure for HIV infection, delegates at a commu......MORE

Does HIV make you fat? Study connects viral load with fat gains

Gus Cairns | 3 years ago

HIV infection or inflammatory changes associated with it may be responsible for fat accumulation an......MORE

Screening study finds high prevalence of early-stage lung cancer among smokers with HIV

Theo Smart | 3 years ago

Using low-dose computed tomography to screen selected people living with HIV who smoke, led to ear......MORE

Smoking is the biggest risk factor for non-AIDS-defining cancers in people living with HIV

Theo Smart | 3 years ago

Smoking appears to contribute most to the burden of non-AIDS-defining cancers diagnosed in people l......MORE

Varenicline helps people with HIV stop smoking, but success rate remains low

Liz Highleyman | 3 years ago

The smoking cessation drug varenicline (Champix, or Chantix in the United States) helped more peopl......MORE

HIV attachment inhibitor BMS-663068 safe and effective in phase 2b study

Liz Highleyman | 3 years ago

Bristol-Myers Squibb's BMS-663068 or fostemsavir, a first-in-class HIV attachment inhibitor that s......MORE

Deferring hepatitis C treatment can lead to liver cancer and death, despite cure

Liz Highleyman | 3 years ago

HIV/HCV coinfected people who delay hepatitis C treatment remain at risk for liver failure, hepatoc......MORE

Progression to severe fibrosis or cirrhosis is common among baby boomers with hepatitis C in the US

Liz Highleyman | 3 years ago

The burden of hepatitis C virus (HCV) infection is high in the US, with a substantial number of in......MORE

Study finds high rates of cancer among older people living with HIV

Theo Smart | 3 years ago

Older people living with HIV (over the age of 65) are at greatly increased risk of HIV-associated c......MORE

Levels of maraviroc in vaginal and rectal tissues may not be high enough for pre-exposure prophylaxis

Liz Highleyman | 3 years ago

Levels of the HIV entry inhibitor maraviroc (Celsentri/Selzentry) in vaginal and rectal tissues did......MORE

Financial incentives did not improve linkage to care or viral suppression in US study

Gus Cairns | 3 years ago

A US study which offered patients gift cards to present themselves for care after testing, and also......MORE

Tenofovir, boosted atazanavir and boosted lopinavir are associated with cumulative risk of developing chronic kidney disease

Gus Cairns | 3 years ago

Three antiretroviral drugs are associated with a slowly increasing rate of chronic kidney disease o......MORE

Two interferon-free regimens show high HCV cure rates for people with HIV and HCV co-infection

Liz Highleyman | 3 years ago

A pair of two-drug, 12-week regimens containing neither interferon nor ribavirin – sofosbuvir (So......MORE

Tenofovir alafenamide equally effective but safer for kidneys and bones than current formulation

Liz Highleyman | 3 years ago

Tenofovir alafenamide (TAF), a new formulation that has lower concentrations in the blood but reach......MORE

Treatment cascades and viral load surveys show how African countries can maximise prevention benefits of HIV treatment

Keith Alcorn | 3 years ago

Reaching ambitious HIV prevention targets in South Africa will require intensified efforts to engag......MORE

Circumcision is reducing HIV incidence in Uganda, Rakai community study shows

Keith Alcorn | 3 years ago

The growing uptake of medical male circumcision by men in the Rakai district of Uganda is leading ......MORE

No HIV transmissions from HIV-positive partner seen in Australian gay couples study

Gus Cairns | 3 years ago

An Australian-based study of gay male couples of opposite HIV status (serodifferent couples) has so......MORE

US PEPFAR abstinence and faithfulness funding had no impact on sexual behaviour in Africa

Keith Alcorn | 3 years ago

Nearly US$1.3 billion spent on US-funded programmes to promote abstinence and faithfulness in sub-S......MORE

HIV maturation inhibitor BMS-955176 looks promising in early study

Liz Highleyman | 3 years ago

A second-generation HIV maturation inhibitor, BMS-955176, demonstrated good safety and high potency......MORE

Starting HIV treatment at CD4 count above 500 reduces the risk of serious illness and death by 44%, African Temprano trial shows

Keith Alcorn | 3 years ago

Starting HIV treatment at a CD4 cell count above 500 reduced the risk of serious illness including ......MORE

Combining PrEP and ART could almost eliminate HIV infection, east African study finds

Gus Cairns | 3 years ago

Giving both pre-exposure prophylaxis (PrEP) and antiretroviral therapy (ART) to heterosexual couple......MORE

XDR-TB in South Africa is largely spread person-to-person, not by failure of drug treatment

Keith Alcorn | 3 years ago

The vast majority of people with extensively drug-resistant tuberculosis (XDR-TB) diagnosed in the......MORE

Stopping cotrimoxazole during antiretroviral therapy raises risk of bacterial illness, malaria, Ugandan trial shows

Keith Alcorn | 3 years ago

Stopping cotrimoxazole prophylaxis increases the risk of serious bacterial infections and malaria, ......MORE

Week-on, weekend-off treatment controls viral load in young people

Keith Alcorn | 3 years ago

Taking an efavirenz-based antiretroviral regimen during the week and taking no medication on two da......MORE

PrEP use rising in San Francisco, but scaling up could further cut new infections

Liz Highleyman | 3 years ago

Use of Truvada (tenofovir/emtricitabine) pre-exposure prophylaxis, better known as PrEP, is increas......MORE

Disappointing result for tenofovir-gel microbicide shows that young women still lack HIV prevention methods they can use

Gus Cairns | 3 years ago

Among some highly promising results from HIV prevention studies presented at the Conference on Retr......MORE

7-country study shows triple-drug combination superior for preventing infant HIV infection

Keith Alcorn | 3 years ago

Implementing the World Health Organization (WHO) recommendation of three-drug antiretroviral treatm......MORE

Breastfeeding mothers often undiagnosed in sub-Saharan Africa

Keith Alcorn | 3 years ago

A large proportion of women in sub-Saharan Africa who are at high risk of transmitting HIV to their......MORE

Pre-exposure prophylaxis also stops 86% of HIV infections in Ipergay study

Gus Cairns | 3 years ago

A French and Canadian study of pre-exposure prophylaxis (PrEP) presented today at the Conference on......MORE

Pre-exposure prophylaxis (PrEP) stops 86% of HIV infections in PROUD study

Gus Cairns | 3 years ago

A study of pre-exposure prophylaxis (PrEP), the English PROUD study, demonstrated the highest effec......MORE

Local spending on HIV prevention in England plunges to 70p per person, per year

Roger Pebody | 3 years ago

HIV prevention in England is underfunded and deprioritised, says the National AIDS Trust (NAT). Whe......MORE

Low CD4 count important risk factor for oral HPV infection in patients with HIV

Michael Carter | 3 years ago

A low CD4 count is the single most important risk factor for oral human papillomavirus (HPV) infect......MORE

Clinicians report two acute HCV infections in Kaiser San Francisco PrEP programme

Liz Highleyman | 3 years ago

Two HIV-negative men gay receiving HIV pre-exposure prophylaxis (PrEP) through Kaiser Permanente in......MORE

HIV testing continues to rise in UK gay men, but safer sex knowledge drops

Roger Pebody | 3 years ago

With health services and HIV prevention organisations now having relentlessly focused on HIV testin......MORE

Researchers may have caught HIV becoming more virulent

Gus Cairns | 3 years ago

A study from Cuba has generated wide media interest because researchers have identified a particula......MORE

Early antiretroviral treatment reduces seizure risk by two-thirds for children with HIV

Michael Carter | 3 years ago

Early antiretroviral therapy prevents the development of epilepsy in children with HIV, results of ......MORE

Patients with HIV can safely receive kidneys from deceased HIV-positive donors, with good five-year survival rates

Michael Carter | 3 years ago

HIV-positive patients can safely receive kidneys from deceased HIV-infected donors, investigators f......MORE

Pilot study suggests that PrEP for other STIs might work

Gus Cairns | 3 years ago

A small pilot study using a daily dose of the antibiotic doxycycline as pre-exposure prophylaxis (P......MORE

A more personalised approach to hepatitis C treatment may improve adherence and completion rates

Roger Pebody | 3 years ago

People receiving treatment for hepatitis C value clinicians who give information and clinical feedb......MORE

VOICE trial: Microbicide gel may have stopped two out of three HIV infections – in the women who used it

Gus Cairns | 3 years ago

The final published paper on the VOICE trial in women in three African countries mainly reinforces ......MORE

Men who have sex with men have other health inequalities as well as poor sexual health, say Public Health England

Roger Pebody | 3 years ago

The UK government’s leading body for public health this week launched a new framework for improvi......MORE

No improvements in CD4 count at diagnosis in African patients in last decade

Gus Cairns | 3 years ago

A study by Harvard Medical School has found that the average CD4 count in sub-Saharan African peopl......MORE

Screening for bone fracture risk should be routine for over-40s with HIV, new guidelines recommend

Keith Alcorn | 3 years ago

Screening for fracture risk should be a routine part of HIV care for all over-40s, and all postmeno......MORE

AbbVie next-generation hepatitis C drugs look promising in early studies

Liz Highleyman | 3 years ago

AbbVie's investigational HCV protease inhibitor ABT-493 and NS5A inhibitor ABT-530 demonstrated go......MORE

African American people’s AIDS conspiracy beliefs best understood in terms of social anxiety and distrust, not ignorance

Roger Pebody | 3 years ago

The idea that AIDS was created as part of a government-led conspiracy to decimate the African Ameri......MORE

Smoking is the main cause of increased risk of heart attack in people with HIV

Roger Pebody | 3 years ago

People living with HIV who smoke have an almost three-fold greater risk of heart attack than HIV-ne......MORE

Starting HIV treatment early and then interrupting is no better than delaying it

Gus Cairns | 3 years ago

A French study that looked at the total amount of time since infection that people with HIV have sp......MORE

Many HIV-positive people’s understanding of the law on HIV transmission is “weak and patchy”

Roger Pebody | 3 years ago

Many people living with HIV in England have a limited understanding of the law which leaves them ei......MORE

Substance use and social problems predict HIV infection in American gay men

Roger Pebody | 3 years ago

American gay men reporting depression, childhood sexual abuse, stimulant use, other substance use a......MORE

Successful peer-recruited project shows it is possible to do prevention work with gay men in hostile environments

Gus Cairns | 3 years ago

A community education and HIV prevention project that took place among 626 gay  men and other men......MORE

Improved school attendance credited with reducing HIV infections among teenage girls in Uganda

Roger Pebody | 3 years ago

The Ugandan government’s decision to abolish tuition fees for school pupils, the resulting improv......MORE

HCV prevention campaigns need to focus on reducing frequency of injecting drug use involving sharing of equipment

Michael Carter | 3 years ago

Sharing injecting equipment is associated with a low per-event probability of hepatitis C virus (HC......MORE

Gay men are better at predicting when they won’t have sex than when they will

Gus Cairns | 3 years ago

A study in which a group of HIV-negative gay and bisexual men from New York were asked to predict e......MORE

Elite controllers may pay a high price for their low viral load

Gus Cairns | 3 years ago

About one in 200 people with HIV maintains an undetectable viral load and high CD4 counts without h......MORE

Experimental siRNA therapy lowers HBsAg levels in people with hepatitis B

Liz Highleyman | 3 years ago

ARC-520, a novel therapy using short interfering RNA, appeared safe and was associated with a reduc......MORE

US guidelines on prevention with people living with HIV now emphasise engagement with care, HIV treatment and social factors

Roger Pebody | 3 years ago

The American public health agency, the Centers for Disease Control and Prevention (CDC) has publish......MORE

Entecavir and tenofovir work well for people with drug-resistant hepatitis B virus

Liz Highleyman | 3 years ago

A combination of entecavir plus tenofovir effectively suppressed hepatitis B virus (HBV) in people ......MORE

CDC researchers publish estimate of effectiveness of condom use in anal sex

Gus Cairns | 3 years ago

A paper this month in the Journal of Acquired Immune Deficiency Syndromes finally makes publicly av......MORE

ART during tuberculosis therapy reduces mortality risk for people with HIV

Michael Carter | 3 years ago

There is a high mortality rate among people living with HIV undergoing treatment for tuberculosis (......MORE

One million people with hepatitis C in the US at high priority for treatment

Liz Highleyman | 3 years ago

An estimated 813,000 people with diagnosed hepatitis C in the US have undergone liver disease stagi......MORE

Many hepatitis C patients with cirrhosis or advanced fibrosis face liver failure and liver cancer

Liz Highleyman | 3 years ago

Nearly one-third of chronic hepatitis C patients with liver cirrhosis and 12% with advanced fibrosi......MORE

Strategies to improve male partner involvement in microbicide research needed

Lesley Odendal | 3 years ago

Vaginal microbicides were partially developed in response to power differentials within sexual rel......MORE

UK government halves the budget of HIV prevention programme for England

Roger Pebody | 3 years ago

The Department of Health’s funding for HIV Prevention England, the national HIV prevention progra......MORE

Smoking doubles risk of death for patients taking HIV therapy

Michael Carter | 3 years ago

Smoking doubles the mortality risk for people with HIV taking antiretroviral therapy, a study publi......MORE

No new HIV infections seen among Kaiser PrEP users

Liz Highleyman | 3 years ago

No new HIV infections have occurred among more than 500 users of the Kaiser Permanente healthcare p......MORE

HIV most often passed on by younger gay men who have undiagnosed HIV, are not on treatment, and have an ongoing partnership

Roger Pebody | 3 years ago

A modelling study based on the UK’s HIV epidemic among gay men estimates that two-thirds of infec......MORE

HIV has become more virulent over time, not less, European study finds

Gus Cairns | 3 years ago

The largest cohort study ever to look at CD4 count and viral loads in HIV-positive people around th......MORE

Sofosbuvir/ledipasvir cures most previously treated hepatitis C patients with cirrhosis

Liz Highleyman | 3 years ago

Difficult-to-treat hepatitis C patients with liver cirrhosis who were not cured with a prior course......MORE

Poor weight gain during first year of ART associated with increased mortality risk for children with HIV in resource-limited settings

Michael Carter | 3 years ago

Poor weight gain after starting antiretroviral therapy (ART) is associated with increased mortality......MORE

European HIV response "falling behind" as Eastern European epidemic grows

Keith Alcorn | 3 years ago

HIV diagnoses have increased by 80% in the European region since 2004, and three quarters of new HI......MORE

Reduced physical function significantly increases mortality risk of middle-aged people living with HIV

Michael Carter | 3 years ago

HIV infection is associated with reduced physical performance, investigators report in the online e......MORE

Safer injecting practices would be better promoted by focusing on pleasure and practical concerns – not the risk of infection

Roger Pebody | 3 years ago

Harm reduction interventions often fail to engage people who inject drugs because they over-emphasi......MORE

Sofosbuvir/ledipasvir with ribavirin cures most people with hepatitis C recurrence after liver transplantation

Liz Highleyman | 3 years ago

An interferon-free regimen of sofosbuvir plus ledipasvir (Harvoni) taken with ribavirin for 12 or 2......MORE

Sofosbuvir + simeprevir shows good results for hepatitis C in real-world use

Liz Highleyman | 3 years ago

Regimens containing sofosbuvir (Sovaldi) – including sofosbuvir plus simeprevir (Olysio) – work......MORE

HIV epidemic will spring back without near-universal diagnosis and treatment, says UNAIDS

Gus Cairns | 3 years ago

“Without scale-up, the AIDS epidemic will continue to outrun the response, increasing the long-te......MORE

British HIV cure survey: most respondents would be prepared to take some health risk to help find a cure for HIV

Gus Cairns | 3 years ago

An online survey that asked people living with HIV, largely from the UK, whether they would partici......MORE

DAAs show good cure rates and liver function improvement for transplant recipients with recurrent HCV

Liz Highleyman | 3 years ago

Several presentations at the American Association for the Study of Liver Diseases (AASLD) Liver Mee......MORE

AbbVie 3D regimen cures recurrent HCV in most liver transplant recipients without cirrhosis

Liz Highleyman | 3 years ago

AbbVie's 3D regimen (newly named Viekirax + Exviera) demonstrated a sustained virological response ......MORE

NHS urgently needs to make PrEP available, say HIV prevention organisations

Roger Pebody | 3 years ago

A group of community organisations working on HIV prevention have called for the NHS to speed up it......MORE

Tenofovir continues to suppresses hepatitis B virus for eight years

Liz Highleyman | 3 years ago

Most people with chronic hepatitis B who are treated with tenofovir for eight years continued to ma......MORE

Tenofovir continues to suppress hepatitis B virus for eight years

Liz Highleyman | 3 years ago

Most people with chronic hepatitis B who are treated with tenofovir for eight years continued to ma......MORE

Daclatasvir + sofosbuvir demonstrates good cure rate for genotype 3 hepatitis C

Liz Highleyman | 3 years ago

An all-oral combination of daclatasvir (Daklinza) plus sofosbuvir (Sovaldi), taken for 12 weeks, pr......MORE

Positive response to 'gift tokens for undetectable viral load' trial

Gus Cairns | 3 years ago

A US study presented at last month’s HIV Research for Prevention conference found generally posit......MORE

AbbVie 3D regimen and sofosbuvir/ribavirin show high cure rates for HCV in people with HIV co-infection

Liz Highleyman | 3 years ago

AbbVie's 3D regimen (paritaprevir/ombitasvir/ritonavir plus dasabuvir) with ribavirin for 12 weeks ......MORE

Sofosbuvir + GS-5816 for 12 weeks shows high HCV cure rates, but 8 weeks is less effective for some patients

Liz Highleyman | 3 years ago

  A 12-week oral combination of sofosbuvir plus the experimental NS5A inhibitor GS-5816 demonstra......MORE

HIV in the UK: 76% diagnosed, 90% on treatment, 90% undetectable

Roger Pebody | 3 years ago

The UK’s annual epidemiological report, released yesterday, shows that the country already provid......MORE

Adding pegylated interferon to tenofovir improves odds of HBsAg loss in hepatitis B patients

Liz Highleyman | 3 years ago

People with chronic hepatitis B virus (HBV) infection are more likely to experience favourable trea......MORE

Gay men in UK recommended to receive HPV vaccination

Michael Carter | 4 years ago

HPV vaccination programmes should be extended to gay and other men who have sex with men (MSM), an ......MORE

Merck's grazoprevir/elbasvir combo shows high cure rates, including for people with cirrhosis and HIV/HCV co-infection

Liz Highleyman | 4 years ago

An all-oral regimen of grazoprevir (MK-5172) and elbasvir (MK-8742), taken with or without ribaviri......MORE

Groundbreaking HIV vaccine's effects were real – and could be made to work better

Gus Cairns | 4 years ago

Findings from further studies using a reformulation of the only HIV vaccine that has ever worked in......MORE

Sofosbuvir/ledipasvir and AbbVie 3D regimen cure most people with HCV genotype 4

Liz Highleyman | 4 years ago

Sofosbuvir/ledipasvir without ribavirin and AbbVie's 3D regimen (paritaprevir/ombitasvir plus dasab......MORE

Restoring and maintaining a high CD4 count possible for vast majority of people living with HIV in France

Alain Volny-Anne | 4 years ago

A large French study has shown that the vast majority of people living with HIV who started treatme......MORE

Sofosbuvir/ledipasvir with ribavirin is highly effective for people with decompensated cirrhosis

Liz Highleyman | 4 years ago

An oral regimen of sofosbuvir/ledipasvir plus ribavirin taken for 12 weeks cured most hepatitis C p......MORE

People living with HIV have high survival rates after liver transplants due to HCC

Liz Highleyman | 4 years ago

People with HIV – most of whom had hepatitis B or C co-infection – generally had good outcomes ......MORE

What are the barriers that could stop HIV treatment becoming HIV prevention?

Gus Cairns | 4 years ago

One of the key strategies involved in trying to bring an end to the HIV epidemic is to increase the......MORE

Hepatitis B testing and treatment rates are low among U.S. veterans

Liz Highleyman | 4 years ago

Only 15% of US veterans have been tested for hepatitis B virus (HBV) infection, and among those who......MORE

Hepatitis B testing and treatment rates are low among US veterans

Liz Highleyman | 4 years ago

Only 15% of US veterans have been tested for hepatitis B virus (HBV) infection, and among those who......MORE

Daclatasvir TRIO regimen has good cure rates for hepatitis C patients with or without cirrhosis

Liz Highleyman | 4 years ago

A 12-week all-oral regimen of daclatasvir, asunaprevir and beclabuvir, with or without ribavirin, c......MORE

Young drug injectors on opioid maintenance therapy have lower risk of hepatitis C infection

Liz Highleyman | 4 years ago

Young people who inject drugs (PWID) who undergo opioid agonist maintenance therapy with methadone ......MORE

Misunderstanding of questions regarding anal sex in microbicide HIV prevention trial

Lesley Odendal | 4 years ago

There was widespread misunderstanding and misinterpretation of questions about anal sex being asked......MORE

Once-daily dolutegravir superior to darunavir/ritonavir in 96-week follow-up

Alain Volny-Anne | 4 years ago

Treatment with a triple antiretroviral combination containing once-daily integrase inhibitor dolute......MORE

Doravirine works as well as efavirenz with fewer CNS side-effects

Liz Highleyman | 4 years ago

Once-daily doravirine (MK-1439), an experimental NNRTI, demonstrated viral suppression similar to ......MORE

Sofosbuvir/ledipasvir cures nearly all genotype 1 HCV for people with HIV co-infection

Liz Highleyman | 4 years ago

All but one participant treated for hepatitis C virus (HCV) with a co-formulation of sofosbuvir an......MORE

Sustained virological response to hepatitis C treatment reduces mortality, liver cancer and liver transplants

Liz Highleyman | 4 years ago

People who achieve sustained virological response (SVR) when treated with interferon-based therapy ......MORE

Sofosbuvir/ledipasvir cures nearly all genotype 1 HIV/HCV coinfected patients

Liz Highleyman | 4 years ago

All but one participant treated with a co-formulation of sofosbuvir and ledipasvir (Harvoni) achiev......MORE

Protease inhibitor monotherapy: darunavir/ritonavir less effective than three-drug therapy

Keith Alcorn | 4 years ago

Darunavir/ritonavir monotherapy results in a lower rate of viral suppression after 48 weeks when co......MORE

Truvada PrEP use rising in United States, especially among men

Liz Highleyman | 4 years ago

The number of people using Truvada for pre-exposure prophylaxis (PrEP) in the US is increasing and ......MORE

One third of TB cases in Eastern European HIV clinic survey multi-drug resistant

Alain Volny-Anne | 4 years ago

Around one-third of people living with HIV in Eastern Europe who were diagnosed with tuberculosis (......MORE

Australia performs best in HIV treatment cascade – 62% with undetectable viral load

Keith Alcorn | 4 years ago

Australia and northern European countries are doing far better than North America at retaining peop......MORE

Australia performs best in HIV treatment cascade - 62% with undetectable viral load

Keith Alcorn | 4 years ago

Australia and northern European countries are doing far better than North America at retaining peop......MORE

Generic antiretrovirals could save NHS £1.25 billion over 5 years, study finds

Michael Carter | 4 years ago

Switching all patients taking antiretrovirals in the United Kingdom to generic versions of the drug......MORE

Efavirenz compromises hormonal contraceptive implant

Keith Alcorn | 4 years ago

The widely-prescribed non-nucleoside reverse transcriptase inhibitor substantially reduces levels ......MORE

Do emtricitabine and lamivudine have similar virological efficacy when used in first-line HIV therapy?

Michael Carter | 4 years ago

First-line antiretroviral regimens containing emtricitabine have superior virological efficacy to c......MORE

HIV testing and ongoing relationships are part of 'safer sex' for young gay men

Roger Pebody | 4 years ago

Many young gay men consider ‘safer sex’ to be about more than condom use, according to a qualit......MORE

Injectable rilpivirine shows promise in phase I trials – but may work better for anal than vaginal sex

Gus Cairns | 4 years ago

A phase one dose-finding and safety study in humans of TMC278 LA, a long-acting, injectable formati......MORE

Tenofovir gel use associated with lower HSV-2 risk in women

Lesley Odendal | 4 years ago

The risk of acquiring herpes simplex virus type 2 (HSV-2) was reduced by 46% (aIRR:0.54, 95%CI:0.30......MORE

Injectable cabotegravir makes progress towards human efficacy studies: doubts about injectable rilpivirine

Gus Cairns | 4 years ago

Researchers have determined the dose of an injectable formulation of the integrase inhibitor cabote......MORE

Increased expenditure on social security has benefits for TB control in the EU

Michael Carter | 4 years ago

Increased expenditure on social protection programmes – sickness, disability and unemployment ben......MORE

Research for Prevention conference opens with real hope for an HIV vaccine

Gus Cairns | 4 years ago

“There’s only one Berlin patient still. But by this time next year he will at least be joined b......MORE

Second European PrEP study is closed early due to high effectiveness

Gus Cairns | 4 years ago

In an extraordinary development, a second European scientific trial of pre-exposure prophylaxis (Pr......MORE

Second European PrEP study closes placebo arm early due to high effectiveness

Gus Cairns | 4 years ago

In an extraordinary development, a second European scientific trial of pre-exposure prophylaxis (Pr......MORE

How does a ‘human rights based approach’ work out on the ground? Lessons from South Africa

Roger Pebody | 4 years ago

While international rhetoric on HIV and AIDS frequently invokes human rights, putting these ideas i......MORE

Emerging epidemic of transmitted HIV drug resistance in low- and middle-income countries, with highest burden seen in MSM

Michael Carter | 4 years ago

Prevalence of transmitted drug-resistant HIV has doubled in low- and middle-income countries in rec......MORE

Bedaquiline as part of tailored therapy for MDR- and XDR-TB achieves impressive culture conversion rates

Michael Carter | 4 years ago

Use of the new anti-tuberculosis (TB) drug bedaquiline as part of a tailored regimen achieved high ......MORE

AbbVie 3D HCV regimen well-tolerated in PEARL trials

Liz Highleyman | 4 years ago

AbbVie's 3D hepatitis C regimen containing paritaprevir (ABT-450), ombitasvir, and dasabuvir was ge......MORE

HIV care cascade at Kaiser Permanente varies by sex and age

Theo Smart | 4 years ago

Though there has been improving performance of healthcare delivery at each point of the HIV care ca......MORE

Behavioural and financial incentives may improve HIV treatment outcomes

Theo Smart | 4 years ago

While making medications free can remove barriers to access for individuals who cannot pay for trea......MORE

NNRTIs and protease inhibitors both good for first ART, channelling affects choices

Liz Highleyman | 4 years ago

Non-nucleoside reverse transcriptase inhibitors (NNRTIs) and boosted protease inhibitors work equ......MORE

Infants in southern Africa start antiretroviral therapy late with advanced disease

Lesley Odendal | 4 years ago

Three quarters of infants starting antiretroviral therapy (ART) across eleven clinics in southern A......MORE

No to treating our way out of the epidemic, say South African experts

Keith Alcorn | 4 years ago

No, we cannot treat our way out of the HIV epidemic, was the resounding sentiment of a panel of exp......MORE

No to treating our way out of the epidemic, say South African experts

Lesley Odendal | 4 years ago

No, we cannot treat our way out of the HIV epidemic, was the resounding sentiment of a panel of exp......MORE

Sofosbuvir/ledipasvir safe and effective for genotype 1 HCV

Liz Highleyman | 4 years ago

A single-tablet regimen containing the hepatitis C virus (HCV) nucleotide polymerase inhibitor so......MORE

Inflammatory markers associated with development of diabetes in people taking HIV therapy

Michael Carter | 4 years ago

Low-level elevations in important markers of systemic inflammation are associated with the developm......MORE

High effectiveness seen in English PrEP trial

Gus Cairns | 4 years ago

The Steering Committee* of the PROUD trial of pre-exposure prophylaxis (PrEP) in gay men in England......MORE

Targeted adherence measures and viral load monitoring needed to improve retention in South African ART programme

Lesley Odendal | 4 years ago

57% of people living with HIV in South Africa who are eligible to initiate antiretroviral therapy (......MORE

HIV stigma starts young, but can be corrected, African schoolchildren's study shows

Gus Cairns | 4 years ago

A study conducted among nearly 40,000 school students aged 12 to 14 in nine southern African countr......MORE

Care programme improves clinic attendance and rates of virologic suppression among vulnerable HIV-positive patients in New York

Michael Carter | 4 years ago

Enrollment in a comprehensive care coordination programme significantly improves levels of engageme......MORE

HCV core-antigen testing is a reliable way of detecting acute HCV infections in HIV-positive gay men

Michael Carter | 4 years ago

Hepatitis C virus (HCV) core-antigen testing is a highly reliable way of diagnosing acute HCV infec......MORE

HIV treatment roll-out has had only a modest impact on mortality in Lusaka, Zambia

Michael Carter | 4 years ago

The scale-up of antiretroviral therapy (ART) programmes in Lusaka, Zambia, has been accompanied by ......MORE

HIV-related stigma has increased in Uganda despite treatment roll-out

Michael Carter | 4 years ago

HIV continues to be stigmatised despite increased access to antiretroviral therapy (ART), according......MORE

Counselling during routine HIV care reduces rates of risky sex among people on ART in South Africa

Michael Carter | 4 years ago

HIV prevention counselling delivered during routine care reduces sexual risk behaviour in people re......MORE

The treatment cascade in the United States – good in Ryan White programmes, but overall picture for gay men is poor

Michael Carter | 4 years ago

People living with HIV in the United States who receive their care through the Ryan White HIV/AIDS ......MORE

People with hepatitis B who have cirrhosis should be prioritised for liver cancer screening

Michael Carter | 4 years ago

Liver cancer screening for people with hepatitis B virus (HBV) infection should be targeted at thos......MORE

PrEP will need high adherence, high effectiveness and high coverage in specific populations to be affordable in the US, New York study finds

Gus Cairns | 4 years ago

A study based on New York City that modelled pre-exposure prophylaxis (PrEP) uptake there has found......MORE

Approximately 4.2 million over 50s are now living with HIV

Michael Carter | 4 years ago

Persuasive new data showing the ageing of the global HIV epidemic has been published in the online ......MORE

Nearly half of HIV-positive gay men could benefit from being vaccinated against HPV, say Irish researchers

Gus Cairns | 4 years ago

A study of gay men in Ireland that has investigated the prevalence of infection with the human papi......MORE

Treatment of worm infections leads to increases in CD4 counts and haemoglobin and fall in viral load for HIV-positive women taking ART

Michael Carter | 4 years ago

De-worming is associated with falls in viral load and increases in CD4 count and haemoglobin, in pr......MORE

London gay men: 2% of the population, a quarter of the sexually transmitted infections and half of HIV infections

Roger Pebody | 4 years ago

Men who have sex with men (MSM) living in London have particularly poor sexual health and this is w......MORE

HIV infection associated with an increased risk of the diseases of ageing

Michael Carter | 4 years ago

HIV infection is associated with an increased risk of several diseases of old age, according to Dut......MORE

HCV antibody testing may miss recent infections in gay men living with HIV

Michael Carter | 4 years ago

Nucleic acid testing should be used to diagnose acute hepatitis C virus (HCV) infections in gay men......MORE

People living with HIV in the US are infrequently screened for HCV

Michael Carter | 4 years ago

People living with HIV are infrequently screened for hepatitis C virus (HCV) infection, according t......MORE

Stigma, ambivalence and other priorities – explaining poor adherence to PrEP and vaginal microbicides

Roger Pebody | 4 years ago

HIV stigma, the danger of being mistakenly labelled as having HIV, ambivalence about the research p......MORE

Drug use strongly associated with sex, condomless sex and STIs in gay men living with HIV in England

Gus Cairns | 4 years ago

A large survey of gay and bisexual men living with HIV and attending eight sexual health clinics in......MORE

Learning about additional HIV prevention methods doesn’t undermine gay men’s intentions to use condoms

Roger Pebody | 4 years ago

Health promotion interventions can combine information about condoms and alternative biomedical pre......MORE

Pregnant women need more support on looking after their own health after childbirth – could help retention in Option B+ programmes

Roger Pebody | 4 years ago

Many women living with HIV believe that HIV care for the mother’s own health is unimportant once ......MORE

Longer time to virological failure and less drug resistance seen in people taking Atripla than in people taking separate drugs

Gus Cairns | 4 years ago

An analysis of people who experienced treatment failure on their first-line HIV therapy with a vira......MORE

HIV testing rates are improving in African people in England

Roger Pebody | 4 years ago

Data from two large, community surveys of African people living in England suggest that the proport......MORE

Social inequalities associated with late HIV diagnosis and delayed HIV treatment – European study

Roger Pebody | 4 years ago

Even in the context of western European countries with universal access to health care, there are s......MORE

Poor knowledge of partner HIV status among South African women with recent pregnancy

Michael Carter | 4 years ago

Over 40% of women with recent pregnancy and a third of men with recent partner pregnancy do not kno......MORE

Novel immune-suppressant vaccine completely blocks HIV infection in monkeys: human trials planned

Gus Cairns | 4 years ago

A novel and relatively simple vaccine that can be administered orally has managed to completely blo......MORE

Late enrolment in HIV care declines in sub-Saharan Africa, but majority of people still eligible for immediate ART at diagnosis

Michael Carter | 4 years ago

The proportion of HIV-positive patients in sub-Saharan Africa who entered care late declined signif......MORE

Expanded harm reduction provision achieves impressive reductions in HCV incidence among PWID in Scotland

Michael Carter | 4 years ago

Implementation of comprehensive harm reduction policies has achieved impressive reductions in incid......MORE

HIV superinfection associated with accelerated viral load increase but has no impact on clinical disease progression

Michael Carter | 4 years ago

HIV superinfection has no impact on clinical disease progression, investigators report in the onlin......MORE

Emergent HCV epidemic among young, non-urban people who inject drugs in the United States

Michael Carter | 4 years ago

Incidence of acute hepatitis C virus (HCV) infection increased significantly among young, non-urban......MORE

CBT counselling significantly increases adherence among participants in HIV PrEP study

Michael Carter | 4 years ago

A support intervention based on cognitive behavioural therapy (CBT) significantly improved adherenc......MORE

Study in Malawi shows importance of screening HIV-positive patients for HBV co-infection and using tenofovir-containing regimens

Michael Carter | 4 years ago

Hepatitis B virus (HBV) genotype A1 infection is associated with poor virological control and the r......MORE

Use of drug susceptibility testing to select therapy improves treatment outcomes in patients with MDR- and XDR-TB

Michael Carter | 4 years ago

New research published in the online edition of Clinical Infectious Diseases supports World Health ......MORE

HIV prevention for black African people in the UK is under-resourced and needs to be scaled up

Roger Pebody | 4 years ago

NAT (National AIDS Trust) argues in a recent report that although black African communities in the ......MORE

Study in South African township shows HIV-negative individuals often source of new TB cases in patients with HIV

Michael Carter | 4 years ago

HIV-negative individuals are an important source of new tuberculosis (TB) cases in HIV-positive pat......MORE

Excellent outcomes among people starting HIV therapy at high CD4 counts in Uganda

Michael Carter | 4 years ago

People in Uganda starting antiretroviral therapy (ART) with higher CD4 counts can achieve excellent......MORE

Intimate partner violence intervention reduces HIV incidence and violence against women

Carole Leach-Lemens | 4 years ago

Integrating intimate partner violence (IPV) prevention strategies into HIV prevention programming l......MORE

Risk of invasive pneumococcal disease remains high for people living with HIV

Michael Carter | 4 years ago

People living with HIV continue to be at increased risk of invasive pneumococcal disease, Danish in......MORE

South African women living with HIV subtype C experience rapid CD4 cell loss

Michael Carter | 4 years ago

A third of women living with HIV subtype C have a fall in their CD4 count to below 350 cells/mm3 wi......MORE

Couples-based intervention has impact on HCV incidence and risky sexual behaviour among drug-involved couples in Kazakhstan

Michael Carter | 4 years ago

A couples-based risk reduction intervention reduced hepatitis C virus (HCV) incidence and levels of......MORE

Self-testing has the potential to boost HIV diagnosis rates among MSM in China

Michael Carter | 4 years ago

Self-testing has the potential to boost HIV diagnosis rates among high-risk and hard-to-reach men w......MORE

Mothers starting antiretrovirals in Malawi lost from care more frequently, revealing weaknesses in Option B+ implementation

Carole Leach-Lemens | 4 years ago

Although Malawi’s policy of offering lifelong antiretroviral therapy (ART) to women living with H......MORE

Harm reduction prevents HIV, national evidence from Ukraine and Greece shows

Mara Kardas-Nelson | 4 years ago

Two presentations given at the 20th International AIDS Conference, held in Melbourne, Australia Jul......MORE

Need for scaled up combination prevention for sex workers, Indian and Central American studies show

Mara Kardas-Nelson | 4 years ago

Presentations given at a session considering HIV prevention strategies among female sex workers, wh......MORE

Switching from first-line ART with suppressed viral load linked to treatment failure

Liz Highleyman | 4 years ago

 People who switch away from their initial antiretroviral therapy (ART) regimen when their viral ......MORE

Gay men interested in taking PrEP already report high-risk behaviour

Roger Pebody | 4 years ago

Surveys of gay men in the Netherlands and Australia suggest that some would use condoms less freque......MORE

Young people with HIV respond well to human papillomavirus vaccine

Liz Highleyman | 4 years ago

The quadrivalent human papillomavirus (HPV) vaccine worked as well for teens and young adults with......MORE

What needs to be done to make HIV self-testing a reality?

Roger Pebody | 4 years ago

Self-testing for HIV has great potential to broaden access to HIV testing, the 20th International A......MORE

Nearly half of young gay men in Bangkok not using condoms consistently acquire HIV within five years of starting sex

Gus Cairns | 4 years ago

A survey of young gay men and transgender women (MSM) in Bangkok has found that HIV incidence among......MORE

NAM European HIV prevention survey: final results

Gus Cairns | 4 years ago

A pan-European survey of opinions about HIV prevention methods, conducted by NAM last year and answ......MORE

Of guidelines, targets and resources: the documents that defined the 2014 International AIDS Conference

Gus Cairns | 4 years ago

If there was a phrase that defined the 20th International AIDS Conference, one that surfaced in eve......MORE

Weight gain on ART may raise risk of heart disease and diabetes

Liz Highleyman | 4 years ago

People with HIV in the normal weight range who gain a substantial amount of weight shortly after st......MORE

Interferon-free hepatitis C treatment works for people on methadone or buprenorphine

Liz Highleyman | 4 years ago

People with chronic hepatitis C who are using methadone or buprenorphine to manage opiate addiction......MORE

Most gay men who don’t use condoms are mindful of HIV and attempt to reduce their risk

Roger Pebody | 4 years ago

Three-quarters of Australian gay and bisexual men who report unprotected anal intercourse with casu......MORE

Efavirenz use not linked to neurocognitive impairment

Liz Highleyman | 4 years ago

People who use antiretroviral regimens containing efavirenz (Sustiva or Stocrin, also in the Atripl......MORE

How will people use PrEP? iPrEx users talk condoms, pills, anxiety and relief

Gus Cairns | 4 years ago

Interviews with participants in the US sites of the iPrEx study of pre-exposure prophylaxis show th......MORE

The more drugs gay men have taken, the more likely they are to have unprotected sex

Roger Pebody | 4 years ago

The probability of gay men in England having unprotected anal intercourse is strongly associated wi......MORE

Tackling moral judgments about sex and sexuality is vital for HIV prevention

Roger Pebody | 4 years ago

Scientific advances in biomedical prevention and treatment will not reach transgender people, men w......MORE

ART demand up to 16.8 million by 2016

Lesley Odendal | 4 years ago

The projected demand for antiretroviral therapy (ART) will increase to 16.8 million person-years by......MORE

Strong performance on HIV drugs for mothers doesn't guarantee optimal care for infants, survey shows

Carole Leach-Lemens | 4 years ago

The significant increase in access to antiretroviral therapy for all pregnant women living with HIV......MORE

HIV is increasing in gay men in London because of lack of testing, comparative study finds

Gus Cairns | 4 years ago

A study presented at the 20th International AIDS Conference (AIDS 2014) in Melbourne today compared......MORE

Dolutegravir demonstrates good efficacy despite resistance

Liz Highleyman | 4 years ago

Antiretroviral regimens containing the recently approved HIV integrase inhibitor dolutegravir (Tiv......MORE

Could HIV treatment mean safer sex?

Gus Cairns | 4 years ago

A meta-analysis of every study that has looked at the sexual behaviour of people after starting HIV......MORE

More data suggest increased risk of HIV infection for women using contraceptive injections

Roger Pebody | 4 years ago

A sophisticated meta-analysis, pooling individual-level data on 37,000 women, has found that the us......MORE

Reduced treatment delays for people with drug-resistant TB and HIV co-infection through decentralised care and rapid Xpert MTB/RIF test

Lesley Odendal | 4 years ago

Decentralisation of drug-resistant tuberculosis (DR-TB) management and use of the Xpert MTB/RIF tes......MORE

Anal lesions often resolve without treatment in HIV-positive gay men

Keith Alcorn | 4 years ago

High-grade anal dysplasia is common among gay men living with HIV, but it often resolves spontaneou......MORE

Home-testing acceptable in 'treat everyone' trial: treatment takes longer to accept

Gus Cairns | 4 years ago

The pilot phase of a trial in South Africa that aims to treat everyone living with HIV in a communi......MORE

Treatment as prevention may not work in Africa without couples counselling

Gus Cairns | 4 years ago

A study from Zambia has found that a programme of couples voluntary counselling and testing (CVCT),......MORE

Harm reduction funding meeting only 7% of global need

Keith Alcorn | 4 years ago

International donors are investing only 7% of what is needed to provide adequate harm reduction cov......MORE

Maraviroc fails to match tenofovir/emtricitabine for first-line HIV treatment

Keith Alcorn | 4 years ago

An NRTI-sparing dual antiretroviral regimen containing maraviroc (Celsentri) plus ritonavir-booste......MORE

Meta-analysis: only half the people who start PEP complete the course

Roger Pebody | 4 years ago

There are significant losses at each step of the post exposure prophylaxis (PEP) ‘treatment casca......MORE

Globally, 1 in 12 MSM have been arrested for same-sex behaviour

Roger Pebody | 4 years ago

Laws which criminalise homosexual behaviour – such as those recently passed by Nigeria and Uganda......MORE

Good adherence seen in study of intermittent PrEP

Gus Cairns | 4 years ago

The first results published from the IPERGAY study, a trial of pre-exposure prophylaxis (PrEP) in g......MORE

Novel techniques probed in cure research

Gus Cairns | 4 years ago

Two presentations at the 20th International AIDS Conference in Melbourne described new pathways bei......MORE

Romidepsin activates latent HIV, but does not decrease viral reservoir

Liz Highleyman | 4 years ago

The HDAC inhibitor romidepsin was able to awaken latent HIV in resting T-cells, causing it to start......MORE

Adolescent deaths from AIDS rising, especially among boys

Carole Leach-Lemens | 4 years ago

While new HIV infections have declined among children, adolescents and adults since 2000, HIV-relat......MORE

Reappearance of HIV in "Mississippi Baby" poses questions for early treatment

Gus Cairns | 4 years ago

The 20th International AIDS Conference (AIDS 2014) heard yesterday that the reappearance of HIV in ......MORE

Cash transfers plus care halve HIV risk behaviours in South African adolescents

Carole Leach-Lemens | 4 years ago

Combining unconditional economic support in the form of government cash transfers, school feeding a......MORE

AIDS 2014: Researchers discuss progress towards an HIV cure

Liz Highleyman | 4 years ago

Progress along the multi-pronged path towards a cure for HIV was one of the themes at the 20th In......MORE

Overall PrEP effectiveness in iPrEx OLE study 50%, but 100% in those taking four or more doses a week

Gus Cairns | 4 years ago

The open-label extension of the iPrEx study of pre-exposure prophylaxis (iPrEx OLE) reported its ma......MORE

What is needed to 'step up the pace' on HIV prevention and treatment?

Keith Alcorn | 4 years ago

'Stepping up the pace', the theme of AIDS 2014, will require a new focus on key populations and ge......MORE

Significantly less syphilis in female partners of circumcised men

Gus Cairns | 4 years ago

A study presented today at the 20th International AIDS Conference (AIDS 2014) in Melbourne found po......MORE

Novel TB regimen could reduce treatment duration

Lesley Odendal | 4 years ago

A novel TB drug regimen that could treat drug-sensitive and some forms of drug-resistant TB far mor......MORE

AbbVie 3D regimen cures most genotype 1 HCV in people with HIV and HCV co-infection

Liz Highleyman | 4 years ago

An oral regimen of three direct-acting antivirals plus ribavirin taken for 12 weeks demonstrated a ......MORE

Sofosbuvir + ribavirin cures hepatitis C for more than 80% of people with HIV and HCV co-infection

Liz Highleyman | 4 years ago

An interferon-free regimen of sofosbuvir (Sovaldi) plus ribavirin for 24 weeks led to sustained hep......MORE

Recession and income inequality have fuelled HIV infections in European drug users

Roger Pebody | 4 years ago

In European countries, increases in rates of reported HIV infections among people who inject drugs ......MORE

AIDS 2014 opening ceremony honours Flight MH17 dead with drive to end AIDS by 2030

Keith Alcorn | 4 years ago

The 20th International AIDS Conference (AIDS 2014) opened in Melbourne, Australia, on Sunday evenin......MORE

European CDC cautious about PrEP

Gus Cairns | 4 years ago

The European Centre for Disease Control (ECDC) has issued a paper saying that it cannot make a clea......MORE

Protease inhibitor therapy doesn't reduce the risk of malaria for HIV-positive pregnant women

Michael Carter | 4 years ago

Antiretroviral therapy (ART) based on the protease inhibitor lopinavir/ritonavir does not reduce th......MORE

Study finds no evidence that HIV-positive gay men in UK have increased risk of neurocognitive impairment

Michael Carter | 4 years ago

Prevalence and severity of neurocognitive impairment does not differ between HIV-positive and HIV-n......MORE

High levels of adherence to study medication among women who conceived during HIV PrEP study

Michael Carter | 4 years ago

HIV pre-exposure prophylaxis (PrEP) appears to be an acceptable strategy for safer conception for......MORE

High rates of drug resistance among HIV-positive infants in South Africa

Michael Carter | 4 years ago

There was a high prevalence of antiretroviral drug resistance among infants newly diagnosed with ......MORE

Therapy with newer, safer antiretrovirals an option for the majority of HIV-positive patients

Michael Carter | 4 years ago

The majority of patients taking antiretroviral therapy (ART) that includes drugs associated with ......MORE

Substantial proportion of male HIV infections labelled as 'heterosexual exposure' in UK probably due to sex with other men

Michael Carter | 4 years ago

Up to a fifth of HIV infection among black African men initially classified as 'heterosexual exposu......MORE

HIV prevention needs to support gay men to discuss HIV status and risk, especially in relationships

Roger Pebody | 4 years ago

Gay, bisexual and other men who have sex with men in Scotland rarely talk explicitly about HIV stat......MORE

HIV/HCV co-infection associated with increased risk of osteoporosis and fractures

Michael Carter | 4 years ago

Co-infection with HIV and hepatitis C virus (HCV) is associated with increased risks of low bone ......MORE

Complex needs and overlapping vulnerabilities frequently reported by ‘high-risk’ gay men in Scotland

Roger Pebody | 4 years ago

A quarter of Scottish gay men who are newly diagnosed with HIV or a rectal sexually transmitted inf......MORE

Protease inhibitor therapy increases underlying genetic risk of diabetes for women with HIV

Michael Carter | 4 years ago

Treatment with an antiretroviral regimen based on a protease inhibitor magnifies any underlying gen......MORE

'Robust' evidence of HIV epidemic among people who inject drugs in the Middle East and North Africa

Michael Carter | 4 years ago

There is “robust” evidence of HIV epidemics among people who inject drugs (PWID) in multiple co......MORE

High prevalence of risk behaviour means there's pontential for worsening of HIV epidemic among people who inject drugs in Europe

Michael Carter | 4 years ago

Sharing of injecting equipment and sex without condoms is more frequently reported by people who in......MORE

High prevalence of risk behaviour means there's potential for worsening of HIV epidemic among people who inject drugs in Europe

Michael Carter | 4 years ago

Sharing of injecting equipment and sex without condoms is more frequently reported by people who in......MORE

HCV is a major reason for healthcare utilisation in the United States

Michael Carter | 4 years ago

Patients with hepatitis C virus (HCV) infection are significant users of healthcare services in the......MORE

Health interventions in online cruising environments more acceptable when they take a ‘passive’ approach

Roger Pebody | 4 years ago

A survey of men who have sex with men in Scotland has found that sexual health promotion is accepta......MORE

ART soon after birth for HIV-infected babies can achieve sustained viral suppression and reduce pool of HIV-infected cells

Michael Carter | 4 years ago

Antiretroviral therapy started soon after birth can suppress HIV to extremely low levels and severe......MORE

Gay men who discuss HIV status with sexual partners are less likely to acquire HIV

Roger Pebody | 4 years ago

A case-control study, examining the sexual behaviour of German gay men receiving HIV-negative and H......MORE

HIV infection due to unsafe medical injections may have fallen by almost 90% worldwide in decade after 2000

Michael Carter | 4 years ago

The number of HIV infections in low- and middle-income acquired due to unsafe medical injections by......MORE

Drug-resistant gonorrhoea rates plummet in US

Gus Cairns | 4 years ago

Preliminary results announced at the US 2014 STD Prevention Conference in Atlanta have shown that t......MORE

Low uptake of HCV treatment in England will lead to substantial disease burden by 2035

Michael Carter | 4 years ago

Only 3% of patients with chronic hepatitis C virus (HCV) are treated for their infection each year ......MORE

PrEP users say it provides an ‘extra layer of protection’ and ‘peace of mind’

Roger Pebody | 4 years ago

American gay men who have chosen to take pre-exposure prophylaxis (PrEP) are aware of their own ris......MORE

Current WHO guidelines for use of ART as prevention will benefit only a "fraction" of people with higher CD4 counts and their partners

Michael Carter | 4 years ago

World Health Organization (WHO) guidance on the use of antiretroviral treatment (ART) for the preve......MORE

People starting therapy on a boosted protease inhihibitor don't need to switch after one virological failure episode, study indicates

Michael Carter | 4 years ago

Remaining on the same regimen is a “reasonable” strategy for people taking first-line antiretro......MORE

Three-quarters of women interviewed in Kenya's highest prevalence province say they prefer circumicsed partners

Michael Carter | 4 years ago

Women in Kenya generally have a good understanding of the partial protection against infection with......MORE

Three-quarters of women interviewed in Kenya's highest prevalence province say they prefer circumcised partners

Michael Carter | 4 years ago

Women in Kenya generally have a good understanding of the partial protection against infection with......MORE

Poor infection control procedures lead to HIV transmissions at haemodialysis centre in Saudi Arabia

Michael Carter | 4 years ago

Breaches in infection control procedures were associated with genetically linked HIV transmissions ......MORE

High burden of STIs among people living with HIV in Cape Town in period before they start ART

Michael Carter | 4 years ago

Sexually transmitted infection (STI) rates are high among people living with HIV in the period befo......MORE

Study shows prognostic value of viral load monitoring among people living with subtype C HIV in South Africa

Michael Carter | 4 years ago

Viral load is the single most important predictor of CD4 cell loss among people in South Africa who......MORE

Second analysis concludes that we can't eliminate the long-term possibility of HIV transmission from someone on treatment

Gus Cairns | 4 years ago

A study that estimates the risk that someone living with HIV and taking antiretroviral therapy coul......MORE

Second analysis concludes that treatment doesn't eliminate the long-term risk of HIV transmission

Gus Cairns | 4 years ago

A mathematical model that estimates the risk of HIV transmission from someone taking antiretroviral......MORE

Model shows potential for substantial long-term HIV risk for serodifferent couples, even with new prevention tools

Gus Cairns | 4 years ago

A mathematical model derived from the current knowledge about the efficacy of various different pre......MORE

Model shows potential for substantial long-term HIV risk for serodifferent couples, even with new prevention tools

Michael Carter | 4 years ago

A mathematical model derived from current knowledge about the efficacy of various different prevent......MORE

Men living with HIV have a lower risk of prostate cancer

Michael Carter | 4 years ago

Incidence of prostate cancer is significantly lower among men living with HIV, investigators from C......MORE

Tenofovir HIV PrEP causes no long-term harm to kidneys

Michael Carter | 4 years ago

HIV pre-exposure prophylaxis (PrEP) with tenofovir is associated with mild disturbances in kidney f......MORE

Action needed to tackle co-infection with HIV and visceral leishmaniasis in India

Michael Carter | 4 years ago

HIV and visceral leishmaniasis co-infection is “an under-diagnosed and under-recognised emerging ......MORE

Low vitamin D concentrations associated with poor clinical and virological outcomes among people starting HIV therapy

Michael Carter | 4 years ago

Low vitamin D concentrations are associated with an increased risk of HIV disease progression among......MORE

People living with HIV at higher risk of cancers caused by smoking or viruses, but not all cancers

Michael Carter | 4 years ago

The risk of cancer is increased twofold for people with HIV compared to individuals in the general ......MORE

New US guidelines recommend PrEP

Gus Cairns | 4 years ago

The US Centers for Disease Control and Prevention (CDC) today released new guidelines recommending ......MORE

Daily dosing key to the efficacy of tenofovir-based HIV PrEP

Michael Carter | 4 years ago

Good adherence is key to the efficacy of tenofovir-based HIV pre-exposure prophylaxis (PrEP), accor......MORE

No significant risk of resistance during treatment with Truvada PrEP

Michael Carter | 4 years ago

Treatment with pre-exposure prophylaxis (PrEP) does not involve a significant risk of HIV drug resi......MORE

No significant risk of resistance if HIV infection occurs during use of Truvada PrEP

Michael Carter | 4 years ago

Treatment with pre-exposure prophylaxis (PrEP) does not involve a significant risk of HIV drug resi......MORE

Even moderate drinking increases risk of advanced liver fibrosis for people with HIV and HCV co-infection

Michael Carter | 4 years ago

Even moderate alcohol consumption is associated with an increased risk of advanced liver fibrosis f......MORE

Annual HIV tests for high-risk groups and one-off screening for all others could have a big impact on UK's HIV epidemic

Michael Carter | 4 years ago

The UK’s HIV epidemic could be partially curtailed by annual testing of high-risk groups and one-......MORE

Sofosbuvir + ribavirin is safe and effective for HCV recurrence after liver transplantation

Liz Highleyman | 4 years ago

An interferon-free combination of sofosbuvir (Sovaldi) plus ribavirin taken for up to 24 weeks led ......MORE

Voucher incentives improve engagement with HIV care among people who inject drugs

Michael Carter | 4 years ago

Providing vouchers exchangeable for food or household goods boosts rates of linkage and retention i......MORE

Sustained response to treatment reduces fatigue in hepatitis C patients

Liz Highleyman | 4 years ago

Curative treatment that eliminates hepatitis C virus from the body can reduce central fatigue, one ......MORE

Investigational protease inhibitor TMC310911 highly potent in phase 2 study

Michael Carter | 4 years ago

The investigational ritonavir-boosted protease inhibitor TMC310911 has a potent antiviral effect, f......MORE

Sofosbuvir + ribavirin for 24 weeks is highly effective against HCV genotype 4

Liz Highleyman | 4 years ago

A 24-week regimen of sofosbuvir (Sovaldi) plus ribavirin cured 93% of people with hard-to-treat he......MORE

Early antiretroviral treatment reduces risk of AIDS and HIV-related illness

Michael Carter | 4 years ago

Early antiretroviral therapy significantly reduced the risk of AIDS and HIV-related illness in a la......MORE

PCR testing reveals high prevalence of CNS infections among people living with HIV in Zambia with CNS symptoms

Michael Carter | 4 years ago

There is a high prevalence of central nervous system (CNS) opportunistic infections among people li......MORE

Methadone and buprenorphine-naloxone both associated with reduced HIV risk among people who inject drugs

Michael Carter | 4 years ago

Methadone maintenance therapy and treatment with buprenorphine-naloxone are equally effective at re......MORE

Implementation of a comprehensive harm reduction programme curtailed the HIV epidemic among people who inject drugs in Taiwan

Michael Carter | 4 years ago

Implementation of a comprehensive harm reduction programme successfully contained the HIV epidemic ......MORE

HIV infection increases risk of melanoma

Michael Carter | 4 years ago

HIV infection is associated with an increased risk of melanoma, according to the results of a meta-......MORE

Three-drug AbbVie combination safe and highly effective in treatment of post-transplant hepatitis C recurrence

Keith Alcorn | 4 years ago

A three-drug combination of direct-acting antivirals developed by AbbVie cured hepatitis C genotype......MORE

Sofosbuvir for hepatitis C works well despite multiple negative predictive factors

Liz Highleyman | 4 years ago

Hepatitis C treatment using sofosbuvir (Sovaldi) is highly effective even for people with multiple ......MORE

People living with HIV in the UK still have impaired health-related quality of life

Michael Carter | 4 years ago

People living with HIV in the UK have poorer health-related quality of life (HRQoL) compared to ind......MORE

Sofosbuvir + new GS-5816 NS5A inhibitor is effective against hepatitis C genotypes 1-6

Liz Highleyman | 4 years ago

A new experimental NS5A inhibitor, GS-5816, was shown to be safe and effective when used in an inte......MORE

'Chem sex' commonly reported by UK gay men diagnosed with shigella

Michael Carter | 4 years ago

 'Chem sex' (taking recreational drugs during sex) and attendance at sex parties are commonly repo......MORE

BMS combination cures 90% of genotype 1b hepatitis C in 24 weeks

Keith Alcorn | 4 years ago

A combination of two direct-acting antivirals developed by Bristol-Myers Squibb (BMS) cured 90% of ......MORE

Sofosbuvir + ribavirin is safe and effective for people with hepatitis C who have advanced liver disease

Liz Highleyman | 4 years ago

Sofosbuvir plus ribavirin is a safe option that can lead to sustained response in people with advan......MORE

Abolishing HIV in Rwanda

Gus Cairns | 4 years ago

The achievement of universal HIV coverage in one African country, Rwanda, has resulted in HIV diagn......MORE

Adding interferon to nucleoside antivirals may improve response for people with chronic hepatitis B

Liz Highleyman | 4 years ago

Adding pegylated interferon to entecavir (Baraclude) led to greater hepatitis B virus (HBV) viral l......MORE

AbbVie 3-drug combination cures 92 to 96% of hepatitis C patients with cirrhosis

Keith Alcorn | 4 years ago

The largest study of new direct-acting antivirals yet conducted in people with hepatitis C genotype......MORE

AbbVie 2-drug combination + ribavirin achieves 100% cure in previously untreated genotype 4 hepatitis C

Keith Alcorn | 4 years ago

A combination of two direct-acting antivirals developed by AbbVie cured 100% of previously untreate......MORE

Sofosbuvir/ledipasvir coformulation cures more than 90% of treatment-naive and retreated genotype 1 patients

Liz Highleyman | 4 years ago

A coformulation of sofosbuvir and ledipasvir taken for as little as 8 weeks produced high sustaine......MORE

Sofosbuvir/ledipasvir co-formulation cures more than 90% of treatment-naive and retreated genotype 1 patients

Liz Highleyman | 4 years ago

A co-formulation of sofosbuvir and ledipasvir taken for as little as eight weeks produced high sus......MORE

Sofosbuvir + simeprevir dual therapy shows high cure rates for hepatitis C patients with or without cirrhosis

Liz Highleyman | 4 years ago

A 12-week oral regimen of sofosbuvir (Sovaldi) plus simeprevir (Olysio) without pegylated interfero......MORE

European liver specialists recommend `mix-and-match` approach to new hepatitis C drugs

Keith Alcorn | 4 years ago

The European Association for the Study of the Liver has issued new guidelines for the treatment of ......MORE

European liver specialists recommend 'mix-and-match' approach to new hepatitis C drugs

Keith Alcorn | 4 years ago

The European Association for the Study of the Liver (EASL) has issued new guidelines for the treatm......MORE

Sofosbuvir/ledipasvir produces early cure for 100% of people with HIV and HCV co-infection

Liz Highleyman | 4 years ago

Treatment for 12 weeks with a co-formulation of sofosbuvir and ledipasvir led to sustained respons......MORE

Sofosbuvir/ledipasvir produces early cure for 100% of HIV/HCV coinfected patients

Liz Highleyman | 4 years ago

Treatment for 12 weeks with a coformulation of sofosbuvir and ledipasvir led to sustained response......MORE

Sofosbuvir/ledipasvir is safe and effective for relapsers and hard-to-treat patients

Liz Highleyman | 4 years ago

A coformulation of sofosbuvir and ledipasvir successfully treated a variety of difficult-to-treat p......MORE

88% of previous relapsers achieve hepatitis C cure with simeprevir-based triple therapy

Keith Alcorn | 4 years ago

Almost 90% of European patients who had relapsed after previous treatment with pegylated interferon......MORE

AbbVie interferon-free regimen cures 96% of treatment-experienced genotype 1 hepatitis C infections

Keith Alcorn | 4 years ago

A 12-week course of three direct-acting antivirals developed by AbbVie, plus ribavirin, cured 96.3%......MORE

Can we provide point-of-care viral load tests in poor countries?

Gus Cairns | 4 years ago

It is not impossible to provide mobile, point-of-care viral load tests in resource-poor settings, t......MORE

PROUD UK PrEP study completes enrolment - first data gives participants' background and risk factors

Gus Cairns | 4 years ago

The pilot stage of the PROUD study - the UK's study of HIV pre-exposure prophylaxis (taking HIV dru......MORE

PROUD UK PrEP study completes enrolment – first data give participants' background and risk factors

Gus Cairns | 4 years ago

The pilot stage of the PROUD study – the UK's study of HIV pre-exposure prophylaxis (HIV-negative......MORE

WHO recommends global use of newest hepatitis C drugs, urges price reductions

Keith Alcorn | 4 years ago

The World Health Organization has issued global treatment guidelines for hepatitis C, strongly reco......MORE

Low CD4 count during HIV therapy increases risk of virus-related non-AIDS cancers

Michael Carter | 4 years ago

A poor CD4 response to antiretroviral therapy (ART) is associated with an increased risk of virus-r......MORE

Giving treatment to specific high-risk people may bring down HIV faster than distributing it equally

Gus Cairns | 4 years ago

In a concentrated epidemic, HIV is mainly restricted to – or at least more common in – specific......MORE

Expanded HIV testing may find more acute infections as well as more late presenters

Gus Cairns | 4 years ago

Expanding HIV testing into local hospitals and primary care may not only find more people who have ......MORE

Home sampling for HIV testing – high demand, 1 in 60 are HIV positive

Roger Pebody | 4 years ago

Pilot projects, testing innovative ways for individuals to take their own saliva or blood sample an......MORE

Home sampling for HIV testing – high demand, 1 in 60 are HIV positive

Roger Pebody | 4 years ago

Pilot projects, testing innovative ways for individuals to take their own saliva or blood sample an......MORE

An estimated 29,000 undiagnosed HIV cases in France

Michael Carter | 4 years ago

An estimated 29,000 individuals in France were living with undiagnosed HIV infection in 2010, inves......MORE

No simple relationship between drug use and risky sex in London gay men

Roger Pebody | 4 years ago

Gay men involved in ‘chemsex’ (taking recreational drugs such as mephedrone, GHB/GBL and crysta......MORE

Standard HIV treatment achieves high concentrations in female genital tract and suppresses shedding of virus

Michael Carter | 4 years ago

Standard antiretroviral therapy containing tenofovir, FTC and atazanavir achieves high concentratio......MORE

HIV viral load in semen can differ in two samples provided within one hour

Michael Carter | 4 years ago

HIV can be intermittently detectable in the semen of men taking long-term antiretroviral therapy th......MORE

Risk score can help predict which people living with HIV have highest risk of kidney disease during tenofovir treatment

Michael Carter | 4 years ago

Investigators in the United States have developed a risk score to predict which people living with ......MORE

Hepatitis delta virus co-infection increases risk of poor liver-related outcomes for people living with HIV

Michael Carter | 4 years ago

Co-infection with hepatitis delta virus (HDV) is a major risk factor for hepatic decompensation and......MORE

South African treatment guidelines need to consider viral load, not CD4 count, to achieve greater impact of treatment as prevention: study

Michael Carter | 4 years ago

Recommendations about the initiation of antiretroviral therapy (ART) need to change for the use of ......MORE

Interferon-free BMS combo cures 90% of genotype 1 hepatitis C

Liz Highleyman | 4 years ago

An all-oral regimen of daclatasvir, asunaprevir and BMS-791325 – without interferon or ribavirin ......MORE

HIV incidence is high among pregnant and postpartum women and increases the risk of mother-to-child transmission

Michael Carter | 4 years ago

HIV incidence is high among pregnant and postpartum women and is associated with an increased risk ......MORE

Merck combination suppresses HCV in mono-infected and co-infected patients

Liz Highleyman | 4 years ago

An all-oral combination of the hepatitis C virus (HCV) protease inhibitor MK-5172 and NS5A inhibito......MORE

Early treatment reduces viral reservoirs but does not prevent rebound

Liz Highleyman | 4 years ago

Antiretroviral therapy started during the first several days after infection limited dissemination ......MORE

Dapivirine vaginal ring safe and effective in tissue study, but maraviroc component doesn't work

Liz Highleyman | 4 years ago

Vaginal rings containing the experimental NNRTI dapivirine were well tolerated and blocked HIV infe......MORE

Early antiretroviral therapy may limit gut damage and immune activation

Liz Highleyman | 4 years ago

Starting antiretroviral therapy (ART) at the earliest stage of HIV infection can help prevent immun......MORE

Women with circumcised partners less likely to have HIV, no less likely to use condoms

Gus Cairns | 4 years ago

A study from Orange Farm near Johannesburg in South Africa, the area that hosted the first-ever ran......MORE

High rate of new infections with HPV types associated with a high risk of anal cancer among gay men living with HIV

Michael Carter | 4 years ago

Incidence of anal infection with cancer-associated strains of human papillomavirus (HPV) is high am......MORE

Monitoring may be an option for people living with HIV diagnosed with high-grade pre-cancerous anal lesions

Michael Carter | 4 years ago

Up to 62% of people living with HIV who have high-grade pre-cancerous cell changes may experience a......MORE

Rare case of lesbian transmission of HIV reported in US

Michael Carter | 4 years ago

An extremely rare case of female-to-female sexual transmission of HIV has been reported in the Unit......MORE

Very different levels of PrEP uptake and adherence in three US cities, demonstration project finds

Gus Cairns | 4 years ago

One of the first studies of open-label pre-exposure prophylaxis (PrEP) for at-risk gay men in three......MORE

Heart attack link to abacavir persists in D:A:D study

Gus Cairns | 4 years ago

The nucleoside (NRTI) drug abacavir (Ziagen also in Kivexa/Epzicom) continues to be associated with......MORE

Daclatasvir plus simeprevir are effective against hepatitis C genotype 1b

Liz Highleyman | 4 years ago

An all-oral regimen of daclatasvir plus simeprevir, without interferon or ribavirin, led to sustain......MORE

Efavirenz-based ART matches lopinavir/ritonavir for perinatal HIV treatment

Carole Leach-Lemens | 4 years ago

Pregnant women taking efavirenz-based antiretroviral therapy had significantly better virologic out......MORE

Massive scale-up of HIV testing, plus HIV treatment on diagnosis, needed to curtail UK gay epidemic

Roger Pebody | 4 years ago

Increasing the proportion of HIV-positive gay men in the UK who have an undetectable viral load fro......MORE

Only having sex with same-status partners is an HIV prevention strategy for 40% of gay men

Gus Cairns | 4 years ago

A study from Seattle has found that only having sex with men of the same HIV status was by far the ......MORE

Rejecting serodiscordant partners is HIV prevention strategy of choice for 40% of gay men

Gus Cairns | 4 years ago

A study from Seattle has found that avoiding men of the opposite HIV status was by far the most com......MORE

Sexually transmitted infections greatly increase the risk of HIV infection in pregnancy

Carole Leach-Lemens | 4 years ago

Pregnant women in Kenya have a similar risk of HIV infection during pregnancy to serodiscordant cou......MORE

New NNRTI doravirine matches efavirenz for first-line HIV treatment

Liz Highleyman | 4 years ago

The next-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) doravirine (formerly MK-......MORE

Lopinavir/ritonavir or 3TC PrEP equally protective against infant HIV infection during breastfeeding

Carole Leach-Lemens | 4 years ago

Lopinavir/ritonavir (Kaletra) or 3TC (lamivudine, Epivir) proved equally protective as infant proph......MORE

Heart attack risk in people with HIV may be falling – but not in women

Gus Cairns | 4 years ago

A number of studies at last week’s Conference on Retroviruses and Opportunistic Infections (CROI)......MORE

Nipping HIV in the bud: could we use genotyping to interrupt transmission?

Gus Cairns | 4 years ago

The Conference on Retroviruses and Opportunistic Infections (CROI) this year heard a number of pres......MORE

Novel two-drug maintenance combination works at least as well as triple therapy: stage set for long-lasting injectable formulation

Gus Cairns | 4 years ago

An oral combination therapy of two antiretroviral drugs, the non-nucleoside rilpivirine (Edurant, a......MORE

Protected T-cells persist and proliferate in HIV gene therapy study

Liz Highleyman | 4 years ago

Genetically modified CD4 T-cells lacking CCR5 co-receptors reach high levels in the body and are re......MORE

Raltegravir has the edge over two protease inhibitors in three-drug comparison study

Gus Cairns | 4 years ago

In a head-to-head comparison of three drugs presented at the 21st Conference on Retroviruses and Op......MORE

The 'Boston patients' experience HIV rebound after stem cell transplants

Liz Highleyman | 4 years ago

HIV has re-emerged in two Boston men who underwent experimental antiretroviral therapy interruption......MORE

Younger women not at higher risk of HIV from relationships with older men, South African study finds

Keith Alcorn | 4 years ago

Sex with older men is not placing women under 30 at higher risk of HIV infection in rural South Afr......MORE

Self-testing encourages very high uptake of HIV testing in Malawi study

Keith Alcorn | 4 years ago

A community-based self-testing programme achieved 76% uptake of HIV testing in urban Malawi, with v......MORE

Male life expectancy nine years shorter due to lower male uptake of HIV treatment in rural South Africa

Keith Alcorn | 4 years ago

Male life expectancy in rural South Africa has improved far less dramatically than women’s life e......MORE

Raltegravir plus boosted darunavir shown to be safe and effective for first-line ART

Liz Highleyman | 4 years ago

An NRTI-sparing initial regimen of raltegravir (Isentress) plus boosted darunavir (Prezista) worked......MORE

HIV attachment inhibitor BMS-663068 shows good safety and efficacy in phase 2b study

Liz Highleyman | 4 years ago

Combination therapy using a novel HIV attachment inhibitor demonstrated good safety and effectivene......MORE

Maternal deaths due to HIV not declining despite PMTCT successes in South Africa

Keith Alcorn | 4 years ago

Improvements in prevention of mother-to-child transmission of HIV (PMTCT) in South Africa are not t......MORE

HIV incidence at record high in young gay black men in southern USA

Gus Cairns | 4 years ago

HIV incidence in young black gay men in Atlanta, Georgia in the US is running at 12.1% a year – o......MORE

People with HIV more likely to die after diagnosis of many common cancers in US

Keith Alcorn | 4 years ago

People with HIV are more likely to die from many common cancers than the rest of the US population,......MORE

Monkey studies confirm viability of injectable PrEP drug

Gus Cairns | 4 years ago

Two studies in monkeys of an injectable formulation of the third-generation integrase inhibitor dr......MORE

Sofosbuvir & ribavirin cures 75% of genotype 1 HIV/HCV co-infected patients

Liz Highleyman | 4 years ago

An interferon-free regimen of sofosbuvir plus ribavirin for 24 weeks led to sustained response in t......MORE

AbbVie '3D' combination cures 99% of genotype 1b hepatitis C

Keith Alcorn | 4 years ago

A 12-week triple combination of direct-acting antivirals developed by AbbVie cured at least 99% of ......MORE

Simeprevir cures almost 80% of first-time coinfected hepatitis C patients

Keith Alcorn | 4 years ago

The next-generation hepatitis C protease inhibitor simeprevir cured almost 80% of previously untre......MORE

Simeprevir cures almost 80% of first-time co-infected hepatitis C patients

Keith Alcorn | 4 years ago

The next-generation hepatitis C protease inhibitor simeprevir cured almost 80% of previously untre......MORE

Faldaprevir plus interferon and ribavirin cures hepatitis C in most people with HIV/HCV co-infection

Liz Highleyman | 4 years ago

The hepatitis C protease inhibitor faldaprevir added to pegylated interferon and ribavirin cured he......MORE

Six-week oral treatment can cure hard-to-treat hepatitis C patients

Liz Highleyman | 4 years ago

Interferon- and ribavirin-free treatment using sofosbuvir, ledipasvir and a third direct-acting dru......MORE

No-one with an undetectable viral load, gay or heterosexual, transmits HIV in first two years of PARTNER study

Gus Cairns | 4 years ago

The second large study to look at whether people with HIV become non-infectious if they are on anti......MORE

A cure may need multiple components, workshop delegates hear

Gus Cairns | 4 years ago

Delegates at the community cure workshop in advance of the 21st Conference on Retroviruses and Oppo......MORE

Older age associated with bigger increases in viral load and falls in CD4 count in patients not taking HIV treatment

Michael Carter | 4 years ago

Results of a large observational study underline the importance of closely monitoring viral load in......MORE

Reconnecting patients lost to follow-up with care can prevent new HIV transmissions

Michael Carter | 4 years ago

The number of HIV transmissions can be reduced by tracing patients who drop out of HIV care, accord......MORE

Big gaps in engagement with HIV care and virological suppression between US states

Michael Carter | 4 years ago

The proportion of people living with HIV linked to and retained in HIV care varies considerably bet......MORE

Guidelines for HIV testing in non-specialist settings not being followed in the UK

Michael Carter | 4 years ago

UK guidelines issued in 2008 concerning HIV testing in general medical and primary care settings ar......MORE

HIV treatment as prevention: the Ugandan experience

Michael Carter | 4 years ago

Antiretroviral therapy (ART) is associated with a substantial and sustained reduction in the risk o......MORE

Young people who acquire HIV in Uganda report poor communication and mistrust in their relationships

Roger Pebody | 4 years ago

Compared with young people who remain HIV negative, recent seroconverters in Rakai, Uganda describe......MORE

HIV treatment as prevention: the experience in British Columbia

Michael Carter | 4 years ago

Expanded coverage of HIV therapy in British Columbia has been accompanied by a 42% reduction in HIV......MORE

Truvada PrEP does not harm the kidneys, trial shows

Michael Carter | 4 years ago

HIV pre-exposure prophylaxis (PrEP) with FTC/tenofovir (Truvada) is associated with only mild distu......MORE

HIV prevalence and incidence fall in Kenya

Michael Carter | 4 years ago

HIV incidence and prevalence are declining in Kenya, investigators report in the online edition of ......MORE

A low CD4 cell count despite viral suppression with HIV treatment is associated with a big increase in mortality risk

Michael Carter | 4 years ago

A low CD4 cell count is associated with increased mortality risk, even if people are taking virolog......MORE

Wide range of factors contribute to high HIV risk among black MSM in the US

Michael Carter | 4 years ago

Demographic, behavioural, economic and biological factors are all associated with increased HIV ris......MORE

Dosing errors of liquid AZT "exceedingly" common and related to poorer HIV health literacy

Michael Carter | 4 years ago

Dosing errors are “exceedingly” common when adults are preparing paediatric doses of liquid ant......MORE

Unprotected receptive anal sex is the key risk factor among UK gay men for rectal LGV infection

Michael Carter | 4 years ago

Unprotected receptive anal sex is the key risk factor for rectal LGV (lymphogranuloma venereum) inf......MORE

Black people have low levels of engagement and retention in HIV care in the US

Michael Carter | 4 years ago

Intensified efforts are needed to improve engagement by black people in the HIV care continuum in t......MORE

High incidence of antiretroviral prescribing errors in Nigeria

Michael Carter | 4 years ago

Antiretroviral prescribing errors are common in Nigeria, according to results of a large prospectiv......MORE

‘Not quite normal’ – exploring poor mental health in gay men

Roger Pebody | 4 years ago

Although legal and social equality for gay people is further advanced in the Netherlands than in mo......MORE

HIV associated with increased risk of MDR-TB

Michael Carter | 4 years ago

HIV infection is associated with an increased risk of multi-drug-resistant tuberculosis (MDR-TB), r......MORE

HIV increases fracture risk, say Danes

Michael Carter | 4 years ago

HIV infection increases the risk of fractures, Danish investigators report in the online edition of......MORE

Close link between HIV and hepatitis C transmission networks

Michael Carter | 4 years ago

HIV and hepatitis C virus (HCV) transmission networks are closely linked, according to Swiss resear......MORE

HIV testing interventions should challenge fears of a positive result

Roger Pebody | 4 years ago

Among gay and bisexual men in Glasgow, not having recently taken an HIV test is associated with bei......MORE

Higher pill burden is associated with poorer adherence to HIV therapy and reduced chances of achieving an undetectable viral load

Michael Carter | 4 years ago

Lower pill burden is associated with higher rates of adherence to HIV treatment and better virologi......MORE

Gay and bisexual men in UK warned of Shigella outbreak

Michael Carter | 4 years ago

Gay and bisexual men in the UK are being targeted with a new health information campaign warning th......MORE

US medical societies launch new hepatitis C treatment guidelines

Liz Highleyman | 4 years ago

The American Association for the Study of Liver Diseases (AASLD), Infectious Diseases Society of Am......MORE

Average CD4 cell count at time HIV therapy was started increased among young people in New York City after 2009

Michael Carter | 4 years ago

The average CD4 cell count at which young people living with HIV in New York City started antiretro......MORE

Taking one to tango: how restricting responsibility for safer sex to individuals hinders talking about safer sex

Gus Cairns | 4 years ago

A discussion paper based on a Canadian project that invited HIV-negative and HIV-positive gay men t......MORE

Successful HIV drug resistance testing is possible when viral load is low

Michael Carter | 4 years ago

HIV drug resistance testing can perform well, even when viral load is as low as 250 copies/ml, resu......MORE

Ongoing challenges in providing PMTCT in Kenya and Malawi

Lesley Odendal | 4 years ago

Ongoing systemic issues are affecting the implementation of the 2010 World Health Organisation (WHO......MORE

Significant attrition at each step of the HIV care 'cascade' in British Columbia

Michael Carter | 4 years ago

Patients are being lost at each stage of the HIV care ‘cascade’ in British Columbia, Canada. In......MORE

Long-term immune response to vaccines is impaired in people with HIV

Michael Carter | 4 years ago

The long-term immune response to most vaccines is impaired in people with HIV, according to the res......MORE

Cotrimoxazole prophylaxis neither reduces TB risk nor complicates TB diagnosis in people with HIV

Michael Carter | 4 years ago

Cotrimoxazole prophylaxis has no impact on incidence or detection of tuberculosis (TB) in people wi......MORE

Modelling study – self testing could lead to more HIV infections

Roger Pebody | 4 years ago

If gay men replace clinic-based HIV testing with less sensitive home tests, the prevalence and inci......MORE

Testing HCV positive has a sustained impact on drug injecting behaviour

Michael Carter | 4 years ago

Diagnosis with hepatitis C virus (HCV) is associated with a sustained reduction in injecting drug u......MORE

Gay men’s HIV risk varies hugely between individuals and over time, cohort study finds

Gus Cairns | 4 years ago

A study that looked at the way risk of HIV transmission changed over time in a group of gay men dur......MORE

Low lymphocyte count a risk factor for infections for people taking HCV therapy

Michael Carter | 4 years ago

A low lymphocyte count is associated with an increased risk of infections during hepatitis C virus ......MORE

Opt-out HIV testing for acute medical admissions to UK hospitals works

Michael Carter | 4 years ago

Opt-out HIV testing for general medical admissions to hospital is feasible, cost-effective and lead......MORE

Immune suppression associated with reduced risk of TB transmission to household contacts of people with HIV/TB co-infection

Michael Carter | 4 years ago

HIV-related immune suppression is associated with a reduced risk of tuberculosis (TB) transmission ......MORE

Computerised counselling for patients taking HIV therapy can reduce viral load, improve treatment adherence and reduce rates of risky sex

Michael Carter | 4 years ago

Computerised counselling can achieve reductions in viral load and HIV transmission risk behaviour, ......MORE

Study identifies factors associated with mortality in HIV-positive people with cryptococcal meningitis

Michael Carter | 4 years ago

Rapid diagnosis and effective antifungal therapy are essential to reduce mortality rates in HIV-pos......MORE

Regular clinic attendance especially beneficial for people with HIV who have low CD4 counts

Michael Carter | 4 years ago

People taking HIV treatment who have a low CD4 cell count are especially likely to achieve an undet......MORE

High viral load levels in young people newly linked with HIV care in the US

Michael Carter | 4 years ago

Approximately a third of young people newly linked to HIV care in the United States have viral load......MORE

African studies identify strategies for improving treatment adherence, retention in care

Mara Kardas-Nelson | 4 years ago

Getting people tested for HIV is one thing; getting them onto antiretrovirals (ARVs) another; and r......MORE

TB/HIV programmatic challenges highlighted at ICASA

Lesley Odendal | 4 years ago

The presence of tuberculosis (TB) at the initiation of antiretroviral therapy (ART) predicts retent......MORE

Life expectancy now considerably exceeds the average in some people with HIV in the US

Gus Cairns | 4 years ago

A study from the US has found that some groups of people with HIV, especially those treated before ......MORE

Large US study shows which HIV tests are most accurate

Roger Pebody | 4 years ago

Differences in the performance of commonly used HIV tests lead to substantial differences in the nu......MORE

People newly diagnosed with HIV/STIs often have individuals with undiagnosed HIV in their social network

Michael Carter | 4 years ago

Asking people who are newly diagnosed with HIV or a sexually transmitted infection (STI) to recruit......MORE

Patients newly diagnosed with HIV/STIs often have individuals with undiagnosed HIV in their social network

Michael Carter | 4 years ago

Asking patients newly diagnosed with HIV or a sexually transmitted infection (STI) to recruit conta......MORE

Short course of ART during primary HIV therapy has immunological and virological benefits after treatment is stopped

Michael Carter | 4 years ago

A short course of antiretroviral therapy during primary HIV infection (PHI) has immunological and v......MORE

Short course of ART during primary HIV infection has immunological and virological benefits after treatment is stopped

Michael Carter | 4 years ago

A short course of antiretroviral therapy during primary HIV infection (PHI) has immunological and v......MORE

Botswana's ART programme achieves good results

Michael Carter | 4 years ago

Botswana’s antiretroviral treatment (ART) programme has achieved good results, analysis of nine y......MORE

Implementing viral load testing in resource-limited settings: one size does not fit all

Mara Kardas-Nelson | 4 years ago

Routine viral load can be done in low-resource settings, Helen Bygrave of Médecins Sans Frontière......MORE

Decentralisation of care reduces HIV and TB-related deaths, illness in Swaziland and Uganda

Mara Kardas-Nelson | 4 years ago

New studies from Eastern and Southern Africa add to  mounting evidence that anti-retroviral therap......MORE

Gilead two-drug hep C combination cures 94% of genotype 1 patients in eight weeks

Keith Alcorn | 4 years ago

A two-drug combination of sofosbuvir and ledipasvir cured 94% of previously untreated patients with......MORE

Gilead two-drug hep C combination cures 94% of genotype 1 patients in 8 weeks

Keith Alcorn | 4 years ago

A two-drug combination of sofosbuvir and ledipasvir cured 94% of previously untreated patients with......MORE

Health systems, not family factors, most crucial in PMTCT outcomes, Kenyan study shows

Lesley Odendal | 4 years ago

Women who learn of their HIV infection during pregnancy are at higher risk of vertical transmission......MORE

Widespread support for HIV PrEP among infectious disease doctors in the US and Canada

Michael Carter | 4 years ago

Three-quarters of infectious disease specialists in the United States and Canada are supportive of ......MORE

Starting antiretroviral therapy significantly reduces the risk of decompensated liver disease for men with HIV/HCV co-infection

Michael Carter | 4 years ago

Starting antiretroviral therapy (ART) significantly reduces the risk of serious liver disease for p......MORE

Study provides information on sexual health of male sex workers in England

Michael Carter | 4 years ago

Male sex workers are significantly more likely to be diagnosed with certain sexually transmitted in......MORE

HIV treatment in South Africa has had "astounding" benefits

Michael Carter | 4 years ago

The roll-out of antiretroviral therapy (ART) in South Africa has achieved “astounding” results,......MORE

Good adherence to HIV treatment, undetectable viral load, reduce the risk of anal infection with high-risk HPV types for MSM with HIV

Michael Carter | 4 years ago

Prevalence of anal HPV (human papillomavirus) infection is significantly higher among men with HIV ......MORE

Men with penile HPV infection have an increased risk of acquiring HIV

Michael Carter | 4 years ago

Men with penile human papillomavirus (HPV) infection have an increased risk of acquiring HIV, inves......MORE

NAM prevention survey results: testing underestimated, support for treatment as prevention, reservations about PrEP

Gus Cairns | 4 years ago

A survey of beliefs and opinions on HIV prevention options, conducted by NAM as part of a programme......MORE

NAM prevention survey: support for treatment as prevention, but reservations about PrEP

Gus Cairns | 4 years ago

A survey of beliefs and opinions on HIV prevention options, conducted by NAM as part of a programme......MORE

Severity of HIV seroconversion illness associated with subsequent disease progression

Michael Carter | 4 years ago

Severity of symptoms during primary HIV infection (PHI) is associated with subsequent disease progr......MORE

For women, HIV treatment based on atazanavir/ritonavir involves twice the risk of failure compared to efavirenz-containing therapy

Michael Carter | 4 years ago

Treatment outcomes differ between women taking first-line antiretroviral therapy based on ritonavir......MORE

Hepatitis C virus dried on inanimate surfaces can remain infectious for up to six weeks

Michael Carter | 4 years ago

Dried spots of blood contaminated with hepatitis C virus (HCV) can remain infectious for up to six ......MORE

Major UK study shows rise in HIV testing, but only a quarter of gay men tested in previous year

Roger Pebody | 4 years ago

Data from three, large representative samples of the UK population over the last two decades show a......MORE

Increasing diversity of sexual experience – major UK study

Roger Pebody | 4 years ago

There has been significant change in British people’s sexual behaviour and attitudes in recent de......MORE

Condomless sex increasing in US gay men – especially in HIV-negative and untested men

Gus Cairns | 4 years ago

The proportion of gay men in the US who have had anal sex without a condom at least once in the pas......MORE

Entecavir + tenofovir works well for people with hepatitis B who have had prior treatment failure

Liz Highleyman | 4 years ago

A dual regimen of entecavir (Baraclude) plus tenofovir (Viread) for 48 weeks led to virological res......MORE

Micronutrient supplements delay HIV disease progression for patients with higher CD4 cell counts

Michael Carter | 4 years ago

Long-term micronutrient supplementation delays HIV disease progression in patients with higher CD4 ......MORE

Early ART only increases TB IRIS risk for people with HIV who have a CD4 cell count below 50

Michael Carter | 4 years ago

A low CD4 cell count increases the risk of immune reconstitution inflammatory syndrome (IRIS) for p......MORE

Faldaprevir effective across patient sub-groups with several baseline characteristics associated with treatment outcomes

Michael Carter | 4 years ago

The experimental hepatitis C virus (HCV) protease inhibitor is efficacious across a range of subgro......MORE

After diagnosis of hepatitis C, some gay men willing to consider risk-reduction practices

Roger Pebody | 4 years ago

HIV-positive gay men living with HIV in France need better information about the sexual transmissio......MORE

Proportion of people in southern Africa starting ART with advanced HIV disease falls

Michael Carter | 4 years ago

The proportion of people in sub-Saharan Africa who started antiretroviral therapy (ART) with advanc......MORE

Ritonavir the cause of the interaction between telaprevir and ritonavir-boosted atazanavir

Michael Carter | 4 years ago

Ritonavir is the cause of the detrimental bi-directional interaction between telaprevir and ritonav......MORE

Urgent need to address "resurgent" gay global epidemic, says English public health chief

Gus Cairns | 4 years ago

There is an increasing and potentially catastrophic HIV and sexual health epidemic in gay men and m......MORE

Partner notification highly effective at finding new HIV cases, but a third who could be tested are missed

Gus Cairns | 4 years ago

Systematically contacting and notifying the sexual partners of people newly diagnosed with HIV is a......MORE

Faldaprevir safe and effective in HCV treatment-experienced patients

Michael Carter | 4 years ago

The investigational hepatitis C virus (HCV) protease inhibitor faldaprevir is a safe and effective ......MORE

People who aren't taking HIV treatment are a major source of transmitted resistance in Swiss gay men

Michael Carter | 4 years ago

Individuals who have never taken antiretroviral therapy (ART) are the main source of transmitted HI......MORE

Largest ever number of HIV diagnoses in UK gay men – due to increased testing and new infections

Roger Pebody | 4 years ago

3250 gay men were diagnosed with HIV in the United Kingdom during 2012, the largest number of cases......MORE

Systematic review and meta-analysis shows equivalence of 3TC and FTC

Michael Carter | 4 years ago

The nucleoside reverse transcriptase inhibitors (NRTIs) 3TC and FTC are equally effective, results ......MORE

AbbVie reports 96% cure rate for interferon-free hepatitis C regimen in phase 3 study

Keith Alcorn | 4 years ago

An interferon-free combination of three drugs plus ribavirin achieved a sustained virologic respons......MORE

Church attendance associated with late HIV diagnosis among US MSM

Michael Carter | 4 years ago

Church attendance is associated with late HIV diagnosis among men who have sex with men (MSM), acco......MORE

Successful hepatitis C treatment reduces risk of liver cancer and death, but most remain untreated

Liz Highleyman | 5 years ago

Hepatitis C treatment that leads to viral suppression significantly reduces the likelihood of liver......MORE

Harm reduction works: extremely low HIV incidence over almost 20 years among people who inject drugs in Australia

Michael Carter | 5 years ago

Incidence of new HIV infections among people who inject drugs in Australia is extremely low, result......MORE

Sofosbuvir/ribavirin for 24 weeks cures most genotype 3 hepatitis C patients, adding interferon may help difficult-to-treat

Liz Highleyman | 5 years ago

A dual oral regimen of sofosbuvir plus ribavirin led to sustained response for 93% of genotype 2 he......MORE

Faldaprevir plus pegylated interferon/ribavirin leads to early sustained response in people with HIV and HCV co-infection

Liz Highleyman | 5 years ago

The hepatitis C protease inhibitor faldaprevir plus pegylated interferon and ribavirin improved 4-w......MORE

Rifampicin dose can be increased safely in TB treatment, may shorten duration

Mara Kardas-Nelson | 5 years ago

Increasing the daily dose of rifampicin within the current TB treatment regimen from 10mg/kg to 15m......MORE

Audit shows many high HIV prevalence areas in England are failing to expand HIV testing

Michael Carter | 5 years ago

Most sexual health commissioners for areas in England with a high HIV prevalence have introduced so......MORE

Daclatasvir + asunaprevir cures 85% of genotype 1b hepatitis C patients in Japanese study

Liz Highleyman | 5 years ago

An interferon- and ribavirin-free oral regimen of daclatasvir plus asunaprevir taken for 24 weeks l......MORE

Fixed-dose sofosbuvir/ledipasvir with or without ribavirin cures most genotype 1 hepatitis C patients, LONESTAR study shows

Liz Highleyman | 5 years ago

At least 95% of newly treated people with genotype 1 hepatitis C and prior non-responders achieved ......MORE

Another negative result in the quest for a shorter TB treatment course

Mara Kardas-Nelson | 5 years ago

Results from a Phase III trial that attempted to shorten the treatment duration for drug-sensitive ......MORE

Sofosbuvir taken before or after liver transplant reduces hepatitis C recurrence

Liz Highleyman | 5 years ago

An interferon-free combination of sofosbuvir plus ribavirin administered before liver transplantati......MORE

HIV may be becoming less fit as it adapts to the immune system

Gus Cairns | 5 years ago

HIV, at least in some parts of the world, may be developing a lower replicative capacity as it adap......MORE

Hepatitis B treatment with entecavir or tenofovir lowers, but does not eliminate, liver cancer risk

Liz Highleyman | 5 years ago

Long-term treatment with entecavir can reduce the likelihood that people with chronic hepatitis B w......MORE

Sofosbuvir + ribavirin produces sustained response in 76% of genotype 1 HIV/HCV co-infected people

Liz Highleyman | 5 years ago

An interferon-free regimen of sofosbuvir plus ribavirin taken for 24 weeks cured three quarters of ......MORE

Simeprevir + sofosbuvir produces high sustained response rates for hard-to-treat patients in COSMOS trial

Liz Highleyman | 5 years ago

A 12-week all-oral combination of simeprevir plus sofosbuvir led to sustained virological response ......MORE

BMS interferon-free combination cures over 90% of genotype 1 hepatitis C in 12 weeks

Keith Alcorn | 5 years ago

A combination of three direct-acting antivirals developed by Bristol-Myers Squibb cured chronic hep......MORE

Merck interferon-free combination shows high hepatitis C cure rate in early study

Keith Alcorn | 5 years ago

A two-drug combination of direct-acting antivirals developed by Merck achieved very high cure rates......MORE

Need for expansion of hepatitis C screening among veterans, 'baby-boom' generation and pregnant women highlighted

Keith Alcorn | 5 years ago

Two large studies of the 'baby-boom' generation in the United States suggest that at least 50,000 U......MORE

AbbVie’s two-drug, interferon-free combination cures genotype 1b hepatitis C infection in 95%

Keith Alcorn | 5 years ago

A two-drug combination of direct-acting antivirals developed by AbbVie achieved sustained virologic......MORE

High response rates with telaprevir triple therapy for HIV-positive men with acute hepatitis C

Liz Highleyman | 5 years ago

Adding telaprevir (Incivo or Incivek) to pegylated interferon and ribavirin shortens the duration o......MORE

In ELECTRON trial, 100% of hard-to-treat patients cured with sofosbuvir/ledipasvir plus ribavirin or GS-9669

Liz Highleyman | 5 years ago

Interferon-free regimens of sofosbuvir and ledipasvir plus either ribavirin or GS-9669 taken for 12......MORE

Urgent need to improve sexually transmitted infection screening for MSM in Europe

Roger Pebody | 5 years ago

Across 40 large European cities, less than one third of men who have sex with men (MSM) have been s......MORE

Gay men who don't have anal sex still at high risk of bacterial STIs

Michael Carter | 5 years ago

Gay men may still have a significant risk of syphilis and urethral gonorrhoea even if they do not h......MORE

Once-daily raltegravir effective as maintenance therapy

Liz Highleyman | 5 years ago

Almost all HIV-positive people with undetectable viral load who switched to once-daily raltegravir ......MORE

HIV rebound linked to higher baseline level, slower suppression and low-level viraemia

Liz Highleyman | 5 years ago

Higher baseline viral load, longer time to viral suppression and low-level viraemia below the level......MORE

Simultaneous HIV and tuberculosis therapy doesn't cause problems with liver function

Michael Carter | 5 years ago

Simultaneous treatment with anti-tuberculosis (TB) drugs and antiretroviral therapy (ART) does not ......MORE

Dolutegravir matches or surpasses other regimens for first-line HIV treatment

Liz Highleyman | 5 years ago

The recently approved HIV integrase inhibitor dolutegravir (Tivicay) provides at least equivalent a......MORE

HCV reinfection is common among HIV-positive gay men in Europe

Liz Highleyman | 5 years ago

Nearly 10% of HIV-positive men acquired hepatitis C virus (HCV) a second time after clearing the vi......MORE

High prevalence of osteoporosis and osteopenia in young men with HIV

Michael Carter | 5 years ago

There is an increased prevalence of osteoporosis and osteopenia in young HIV-positive men, Spanish ......MORE

Low CD4 cell count increases heart attack risk for people with HIV

Michael Carter | 5 years ago

Immunodeficiency is an important risk factor for heart attack in people living with HIV, results of......MORE

Social problems and drug and alcohol problems common among people who develop AIDS despite long-term HIV care

Michael Carter | 5 years ago

Psychiatric, drug, alcohol and social care problems are highly prevalent among people who develop s......MORE

Social problems and drug and alcohol abuse common among people who develop AIDS despite long-term HIV care

Michael Carter | 5 years ago

Psychiatric, drug, alcohol and social care problems are highly prevalent among people who develop s......MORE

Pre-test counselling does not reduce sexual risk reduction – findings support streamlined HIV testing procedures

Roger Pebody | 5 years ago

A large randomised controlled trial of rapid HIV testing, with or without risk-reduction counsellin......MORE

Pre-test counselling does not reduce sexual risk taking – findings support streamlined HIV testing procedures

Roger Pebody | 5 years ago

A large randomised controlled trial of rapid HIV testing, with or without risk-reduction counsellin......MORE

Late testing rates declining in Europe, but largely in gay men

Gus Cairns | 5 years ago

Over Europe as a whole, the proportion of people testing late for HIV decreased between 2002 and 20......MORE

Considerable increase in unprotected sex found in French/Canadian gay survey

Gus Cairns | 5 years ago

A French and Canadian online survey of gay men and other men who have sex with men (MSM) appears to......MORE

Tel Aviv and Bucharest signal warnings of new HIV epidemics among people who inject drugs

Keith Alcorn | 5 years ago

A switch to a cheaper injectable illicit drug led to a major outbreak of HIV infection in Tel Aviv,......MORE

Future HIV care will include both novel antiretroviral drugs and new treatment strategies

Liz Highleyman | 5 years ago

HIV treatment in the coming years will include novel antiretroviral agents and new formulations suc......MORE

Faldaprevir demonstrates good early response in genotype 1 HIV/HCV co-infection

Liz Highleyman | 5 years ago

The HCV protease inhibitor faldaprevir added to pegylated interferon and ribavirin increased the li......MORE

Suicide rates tumble in people with HIV in Canadian study but psychiatric drug use remains high in Danish people with HIV

Gus Cairns | 5 years ago

A study presented at the 14th European AIDS Conference last week found that the suicide rate in peo......MORE

Simeprevir with interferon effective for HIV/HCV co-infected people with genotype 1 hepatitis C

Liz Highleyman | 5 years ago

Adding the direct-acting hepatitis C drug simeprevir to pegylated interferon and ribavirin produced......MORE

Dual therapy with Kaletra and 3TC works well regardless of viral load

Liz Highleyman | 5 years ago

A dual combination of lopinavir/ritonavir (Kaletra or Aluvia) plus 3TC (lamivudine, Epivir) as firs......MORE

GSK1265744 rapidly suppresses HIV and appears safe at selected dose

Liz Highleyman | 5 years ago

The experimental HIV integrase inhibitor GSK1265744 demonstrated rapid and potent antiviral activi......MORE

Ensuring good-quality HIV care in Europe: where can we improve?

Keith Alcorn | 5 years ago

Only 20% of people with HIV in Europe have fully suppressed viral load, compared to an estimated 24......MORE

New EACS treatment guidelines strike balance between individual choice and public health, say writers

Gus Cairns | 5 years ago

A new edition of the European AIDS Clinical Society (EACS) guidelines for the treatment of HIV, HIV......MORE

New drugs will bring revolution in hepatitis C treatment

Liz Highleyman | 5 years ago

The advent of direct-acting antiviral agents can rightly be described as a revolution in treatment ......MORE

CCR5 inhibitor cenicriviroc shows good activity against HIV; new formulation may reduce dropouts

Liz Highleyman | 5 years ago

The dual CCR5/CCR2 inhibitor cenicriviroc demonstrated good antiviral activity and tolerability in ......MORE

Number of people infected with drug-resistant HIV in Europe has risen by around 35%

Keith Alcorn | 5 years ago

The number of people in Europe who have become infected with a drug-resistant strain of HIV may hav......MORE

Anal cancer screening may be appropriate for all women with HIV, French researchers suggest

Keith Alcorn | 5 years ago

Women living with HIV had a higher risk of anal pre-cancerous changes than cervical changes linked ......MORE

Experts debate whether HIV cure is 'hype or hope'

Liz Highleyman | 5 years ago

Is a functional cure for HIV feasible within the foreseeable future or is it a hopeless quest robbi......MORE

Researchers and advocates discuss biomedical HIV prevention

Liz Highleyman | 5 years ago

The first day of the 14th European AIDS Conference, which opened yesterday in Brussels, featured a ......MORE

Researchers and advocates discuss the microbicides pipeline in Europe

Liz Highleyman | 5 years ago

The first day of the 14th European AIDS Conference, which opened yesterday in Brussels, featured a ......MORE

Eastern Europe facing quadruple epidemic while governments do nothing, warns UN Special Envoy

Keith Alcorn | 5 years ago

Eastern Europe is facing quadruple, intersecting epidemics of injecting drug use, HIV, tuberculosis......MORE

Vaccine trials – where next?

Gus Cairns | 5 years ago

New efficacy trials of HIV vaccines based on what has been learned in the RV144 vaccine trial in Th......MORE

European physicians condemn impact of Russian anti-gay law on HIV prevention and care

Keith Alcorn | 5 years ago

The European AIDS Clinical Society (EACS) has strongly condemned the discriminatory legal and polic......MORE

Big differences in virological outcomes among people taking first-line HIV therapy in resource-limited settings

Michael Carter | 5 years ago

Virological outcomes vary enormously among people taking antiretroviral therapy in different resour......MORE

HIV-positive people not on antiretrovirals are prone to inflammation-related bone loss

Liz Highleyman | 5 years ago

HIV-positive people not taking antiretroviral therapy experienced more bone mineral density loss at......MORE

HIV-positive young women have adequate response to human papillomavirus vaccine

Liz Highleyman | 5 years ago

HIV-positive girls did not respond as well to the quadrivalent human papillomavirus (HPV) vaccine a......MORE

Only a fifth of pregnancies among women living with HIV in the US are planned

Michael Carter | 5 years ago

Only a fifth of pregnancies among women living with HIV in the United States are planned, research ......MORE

Predicting response to acute hepatitis C treatment in HIV/HCV co-infected people

Liz Highleyman | 5 years ago

HIV/HCV co-infected people with higher HCV viral load, lower CD4 cell counts, older age and unfavou......MORE

Young people (15 to 24 years) especially likely to drop out of HIV care

Michael Carter | 5 years ago

Patients aged between 15 and 24 years are significantly more likely to drop out of HIV compared to ......MORE

Eviplera works well regardless of viral load or CD4 count, may improve lipid levels

Liz Highleyman | 5 years ago

The single-tablet regimen Eviplera (rilpivirine/tenofovir/emtricitabine) worked as well as Atripla ......MORE

Unravelling the mystery of the vaccine trials

Gus Cairns | 5 years ago

There have been thousands of small vaccine trials in the history of HIV – the first one took plac......MORE

HIV monitoring every six months is adequate for people on ART with stable viral suppression

Liz Highleyman | 5 years ago

People with HIV who have their viral load and CD4 cell count monitored every six months were no mor......MORE

Specialised testing and social marketing campaigns increase the detection of acute HIV infection among gay men

Michael Carter | 5 years ago

Big increases in diagnosis rates of acute HIV infection (AHI) can be achieved with the use of targe......MORE

Daclatasvir works well against hepatitis C either with interferon or in all-oral regimen

Liz Highleyman | 5 years ago

A short 12- or 16-week triple regimen of daclatasvir plus pegylated interferon/ribavirin cured more......MORE

Researchers see further positive results with herpes virus-based vaccines in monkeys

Gus Cairns | 5 years ago

One of the biggest news stories at the AIDS Vaccine 2013 conference was the groundbreaking experime......MORE

Female condom choices are expanding – new models have low failure rates and are acceptable to users

Roger Pebody | 5 years ago

A randomised trial has shown that three new models of female condom are non-inferior to the establi......MORE

The monkeys’ tale – how a vaccine might nip HIV in the bud

Gus Cairns | 5 years ago

Four dozen rhesus monkeys may have successfully fought off the monkey equivalent of HIV in a series......MORE

UK patients with MDR-TB have good outcomes but a quarter not receiving the recommended duration of therapy

Michael Carter | 5 years ago

Approximately 25% of people with multidrug-resistant tuberculosis (MDR-TB) in the UK are not comple......MORE

People with HIV have higher risk of death after heart attack

Liz Highleyman | 5 years ago

People with HIV had higher mortality than HIV-negative individuals after hospitalisation for acute ......MORE

Does efavirenz use raise the risk of suicide in people with HIV?

Liz Highleyman | 5 years ago

Suicidal thoughts, attempted suicide and death by suicide were more than twice as common amongst pe......MORE

HIV vaccine conference opens in most promising research atmosphere for years

Gus Cairns | 5 years ago

The 13th – and last – AIDS Vaccine 2013 Conference opened today in Barcelona in an atmosphere o......MORE

Studies look at community vs hospital-based HIV care and medication issues

Liz Highleyman | 5 years ago

HIV-positive people treated at community clinics were more likely to continue receiving care, while......MORE

Revisiting the safety spectrum: how gay men fall into different 'risk classes' for HIV

Gus Cairns | 5 years ago

Gay men fall into different groups that are at radically different risk for acquiring HIV, Canadian......MORE

Liver fibrosis linked to immune activation in HIV/HCV co-infected women

Liz Highleyman | 5 years ago

CD4 and CD8 cell activation were found to be associated with biomarkers of liver fibrosis among HIV......MORE

Many HIV-positive people not receiving recommended prevention counselling as part of their routine care

Michael Carter | 5 years ago

Approximately half of HIV-positive people in the United States are not receiving prevention counsel......MORE

Long-acting antiretrovirals may improve survival for people with poor adherence

Liz Highleyman | 5 years ago

Long-acting antiretroviral formulations taken once-monthly or less have the potential to improve su......MORE

Liver cancer often diagnosed late with poor survival in people with HIV

Liz Highleyman | 5 years ago

Hepatocellular carcinoma is frequently diagnosed at an advanced stage in HIV-positive people with h......MORE

New integrase inhibitor GSK1265744 safe and well tolerated in eight studies

Liz Highleyman | 5 years ago

The investigational HIV integrase inhibitor GSK1265744 was well tolerated, with no notable safety c......MORE

Home-based counselling and testing achieves very high testing rates in Kenya

Carole Leach-Lemens | 5 years ago

A home-based counselling and testing (HBCT) programme in western Kenya achieved 96% uptake of HIV t......MORE

Is HCV infection spreading among HIV-positive gay men in Japan?

Liz Highleyman | 5 years ago

The incidence of acute hepatitis C virus (HCV) co-infection has increased in recent years at the la......MORE

People's friends diagnose brain impairment better than they do themselves

Gus Cairns | 5 years ago

Baseline results from a longitudinal study of 235 gay men with HIV aged 18 to 50 attending the Mort......MORE

Microbicide ring study shows users are reassured about discomfort but develop new worries about safety

Gus Cairns | 5 years ago

A safety and acceptability study of a vaginal ring containing the antiretroviral drugs dapivirine (......MORE

Men attending group sex 'slam parties' don’t all use or inject drugs

Gus Cairns | 5 years ago

There has been considerable publicity in the gay, scientific and general media recently about so-ca......MORE

Cross-sectional study suggests circumcision is having a big impact on HIV rates among men in Orange Farm, South Africa

Michael Carter | 5 years ago

Research conducted in South Africa suggests that the roll-out of circumcision is reducing the preva......MORE

Stribild is effective and well tolerated in older people with HIV

Liz Highleyman | 5 years ago

The Stribild single-tablet regimen matched both Atripla and boosted atazanavir (Reyataz) in efficac......MORE

Who will PrEP be for?

Gus Cairns | 5 years ago

Whether pre-exposure prophylaxis (PrEP) is adopted and is effective as an HIV prevention method dep......MORE

Infection with HIV associated with increased risk of dialysis and end-stage kidney disease

Michael Carter | 5 years ago

HIV infection increases the risk of kidney disease requiring renal replacement therapy or dialysis,......MORE

Political leadership on finance and pace of scale-up needed to realise full potential of treatment as prevention

Keith Alcorn | 5 years ago

Achieving the full potential of antiretroviral treatment as a prevention method will require govern......MORE

Tenofovir vaginal ring protects monkeys on Depo-Provera against HIV-like virus

Liz Highleyman | 5 years ago

An intravaginal ring containing tenofovir protected all but one macaque monkey given hormonal contr......MORE

Uptake of PrEP may be limited because few gay men think they are at risk of HIV infection

Roger Pebody | 5 years ago

Three quarters of gay men seeking HIV testing at a Toronto sexual health clinic were assessed as be......MORE

Treating HCV genotypes 2 and 3 in HIV/HCV co-infected people

Liz Highleyman | 5 years ago

People co-infected with HIV and HCV, mostly with hepatitis C virus (HCV) genotype 3, responded abo......MORE

Making treatment as prevention a reality for people who inject drugs

Keith Alcorn | 5 years ago

People who inject drugs risk being left behind as countries make efforts to scale up antiretroviral......MORE

Single-tablet regimen improves antiretroviral adherence and reduces hospitalisation

Liz Highleyman | 5 years ago

Antiretroviral treatment that requires only a single tablet taken once daily were associated with b......MORE

HPV type 39 linked to anal dysplasia, better screening needed for HIV+ men and women

Liz Highleyman | 5 years ago

About two-thirds of gay men and one-fifth of women tested in Spain were found to have cell or tissu......MORE

Economic austerity affects the way in which HIV-positive Londoners view ‘treatment as prevention’

Roger Pebody | 5 years ago

Discussions of an economic crisis and of austerity contribute to the manner in which people living ......MORE

Switching from Atripla to Eviplera reduces central nervous system side-effects

Liz Highleyman | 5 years ago

People who switched single-tablet regimens from Atripla (efavirenz/tenofovir/emtricitabine) to Evip......MORE

Late HIV diagnosis continues to be a Europe-wide problem

Michael Carter | 5 years ago

Late diagnosis of HIV remains a serious problem across Europe, results of a large study published i......MORE

Interferon response reduces liver disease and death in HIV/HCV co-infected people

Liz Highleyman | 5 years ago

Effective interferon-based therapy that produces sustained virological response led to significant ......MORE

"If I am given antiretrovirals I will think I am nearing the grave" – a challenge for early treatment strategies

Roger Pebody | 5 years ago

Kenyan people living with HIV perceive antiretroviral therapy to be something that is taken in the ......MORE

Raltegravir appears safe for mothers and babies during pregnancy

Liz Highleyman | 5 years ago

Antiretroviral regimens containing the integrase inhibitor raltegravir (Isentress) were shown to be......MORE

Depression linked to episodes of detectable HIV in cerebrospinal fluid

Liz Highleyman | 5 years ago

People who experience episodes of major depressive disorder (MDD) are significantly more likely to ......MORE

South American survey finds rectal microbicide formulated as a douche acceptable

Gus Cairns | 5 years ago

A qualitative study of 140 men who have sex with men (MSM) and transgender women (TGW) is three cit......MORE

Gay men recall seeing mass media campaign, but impact on behaviour remains unclear

Roger Pebody | 5 years ago

A media campaign promoting condom use and sexual health check-ups to gay and other men who have sex......MORE

Novel NNRTI AIC292 works well against drug-resistant HIV

Liz Highleyman | 5 years ago

The next-generation HIV non-nucleoside reverse transcriptase inhibitor (NNRTI) AIC292 showed good a......MORE

New NNRTI MK-1439 interacts with ritonavir but not tenofovir

Liz Highleyman | 5 years ago

Blood levels of MK-1439, a next-generation HIV non-nucleoside reverse transcriptase inhibitor (NNRT......MORE

Dolutegravir shows good efficacy across broad range of patient groups

Liz Highleyman | 5 years ago

The new integrase inhibitor dolutegravir worked better than boosted darunavir for people starting H......MORE

US PrEP prescriptions more likely to go to Southern women

Gus Cairns | 5 years ago

A US survey of the prescribing of Truvada (tenofovir/emtricitabine) to HIV-negative people as pre-e......MORE

New tenofovir formulation works equally well with less effect on kidneys and bones

Liz Highleyman | 5 years ago

Tenofovir alafenamide (TAF), a new formulation that produces higher drug levels in cells but allows......MORE

Raltegravir is a good choice for people with HIV undergoing cancer chemotherapy

Liz Highleyman | 5 years ago

The integrase inhibitor raltegravir (Isentress) may be an optimal choice for many HIV-positive peop......MORE

CD4 gene therapy may enable functional HIV control during treatment interruption

Liz Highleyman | 5 years ago

Two people whose CD4 T-cells were modified to make them resistant to HIV entry experienced substant......MORE

Hepatitis E virus infection associated with HIV and damage to gut mucosa, Zambian study shows

Michael Carter | 5 years ago

The prevalence of hepatitis E virus (HEV) infection is strongly associated with HIV status, results......MORE

Systematic review confirms that regular viral load monitoring assists adherence to HIV therapy

Michael Carter | 5 years ago

Routine viral load monitoring means that people with treatment adherence problems can be identified......MORE

Sexual role versatility among HIV-negative US MSM contributing to high level of HIV incidence

Michael Carter | 5 years ago

Versatility in anal sex roles is a likely explanation for the continued high rate of new HIV transm......MORE

Integration of HIV care into primary care reduces deaths in South African trial

Carole Leach-Lemens | 5 years ago

Integrating HIV care into primary care can improve survival of HIV-positive patients in need of ART......MORE

Loss of kidney function in older people with HIV underlines need for earlier treatment

Michael Carter | 5 years ago

Kidney function deteriorates more rapidly in older people with HIV than in age-matched controls in ......MORE

Intravenous AZT does not provide extra protection against vertical transmission in mothers with undetectable viral load

Carole Leach-Lemens | 5 years ago

Intravenous (IV)-zidovudine (AZT or ZDV) during labour and delivery is effective in reducing mother......MORE

Text messages do not reduce early resumption of sexual activity in recently circumcised men

Carole Leach-Lemens | 5 years ago

Text messaging did not help reduce early resumption of sex after male circumcision (MC) in a large ......MORE

Tenofovir is highly effective for HIV/HBV co-infection, meta-analysis shows

Liz Highleyman | 5 years ago

Home aidsmap.com Full site Tenofovir is highly effective ......MORE

Decompensated cirrhosis increases risk of liver cancer for people with HIV and viral hepatitis co-infection

Michael Carter | 5 years ago

There is a relatively low incidence of hepatocellular carcinoma (HCC) among people living with HIV ......MORE

People with HIV/HCV-co-infection and advanced liver fibrosis can rapidly develop decompensated liver disease

Michael Carter | 5 years ago

People living with HIV who have hepatitis C virus (HCV) co-infection and advanced liver fibrosis ca......MORE

Global AIDS mortality fell by over 20% in last five years, but large inequalities remain between countries

Gus Cairns | 5 years ago

The overall annual death rate from AIDS has fallen by 21% since 2006, the most recent study in the ......MORE

Persisently detectable viral load at any level increases risk of HIV treatment failure

Michael Carter | 5 years ago

For people taking HIV therapy, a persistent detectable viral load at any level is associated with a......MORE

High rates of anal HPV infection among young gay men

Michael Carter | 5 years ago

Prevalence and incidence of anal human papillomavirus (HPV) are high among young gay men, according......MORE

Partner violence may undermine use of female-controlled forms of HIV prevention

Michael Carter | 5 years ago

Women who experience violence from their male partner are less likely to use condoms or diaphragms,......MORE

A fifth of gay men in a relationship with an HIV-negative man have not tested for HIV while in their current relationship

Michael Carter | 5 years ago

A fifth of gay men in a relationship with an HIV-negative male partner have not had an HIV test whi......MORE

Kenyan sex workers and men who have sex with men find PrEP acceptable but worry about others' assumptions

Gus Cairns | 5 years ago

Qualitative interviews from an already published placebo-controlled study of 66 men who have sex wi......MORE

High proportion of Canadian patients with HIV-HCV co-infection and liver cirrhosis are not having ultrasounds to check for liver cancer

Michael Carter | 5 years ago

Over a third of HIV-positive people with hepatitis C virus-related liver cirrhosis are not having r......MORE

Low baseline CD4 cell count associated with greater bone loss after starting HIV therapy

Michael Carter | 5 years ago

A low baseline CD4 cell count is associated with loss of bone mineral density (BMD) during the earl......MORE

Cleared HCV infection associated with increased risk of kidney disease in people with HIV

Michael Carter | 5 years ago

People living with HIV with previous hepatitis C virus (HCV) infection continue to have an increase......MORE

High prevalence of CMV retinitis among HIV-positive patients in Asia and Africa

Michael Carter | 5 years ago

Prevalence of CMV retinitis remains high among HIV-positive patients in resource-limited settings, ......MORE

Considerable increase in unprotected sex found in French gay survey

Gus Cairns | 5 years ago

A French and Canadian online survey of gay men and other men who have sex with men (MSM) appears to......MORE

Legal barrier to self-testing for HIV in UK to be lifted

Keith Alcorn | 5 years ago

The Department of Health announced an important change to HIV testing policy for the United Kingdom......MORE

UK health care workers with HIV to be cleared for dental and surgical work

Keith Alcorn | 5 years ago

Health care workers in the United Kingdom living with HIV will be permitted to carry out exposure-p......MORE

UK healthcare workers with HIV to be cleared for dental and surgical work

Keith Alcorn | 5 years ago

Healthcare workers in the United Kingdom living with HIV will be permitted to carry out exposure-pr......MORE

Pegylated interferon with antiretroviral therapy achieves promising results in patients with difficult-to-treat Kaposi's sarcoma

Michael Carter | 5 years ago

Pegylated interferon alfa-2a (PegIFN) may be an effective therapy for Kaposi's sarcoma (KS) that ha......MORE

High prevalence of heart rhythm disturbance among HIV-positive people on methadone maintenance therapy

Michael Carter | 5 years ago

Spanish investigators have identified a high prevalence of a potentially life-threatening disturban......MORE

CD4 cell count at time of entry to HIV care did not increase significantly between 1992 and 2011

Michael Carter | 5 years ago

The average CD4 cell count of people newly entering HIV care in resource-rich countries did not inc......MORE

Few AIDS diagnoses among people with higher CD4 cell counts, but risk remains elevated for those with a count below 750

Michael Carter | 5 years ago

Incidence of AIDS-defining illnesses remains elevated even when the CD4 cell count is between 500 a......MORE

Immune suppression and smoking history are risks for HPV-related anal disease in HIV-positive gay men

Michael Carter | 5 years ago

Risk factors for human papillomavirus (HPV)-associated anal disease in HIV-positive gay men are sim......MORE

Community study finds no evidence of widespread HCV epidemic among HIV-negative gay men in London

Michael Carter | 5 years ago

Approximately 1% of HIV-negative gay men in London had antibodies to the hepatitis C virus (HCV) in......MORE

A quarter of HIV/HCV-co-infected people in EuroSIDA have received HCV therapy

Michael Carter | 5 years ago

A quarter of HIV-positive people in the EuroSIDA cohort with chronic hepatitis C virus (HCV) co-inf......MORE

Evidence is not yet sufficient to recommend universal treatment, clinicians and community writers say

Gus Cairns | 5 years ago

We do not yet have sufficiently strong evidence to recommend that antiretroviral treatment (ART) sh......MORE

HIV treatment has not led to increasing sexual risk-taking in rural South African communities

Gus Cairns | 5 years ago

A study from a rural area in the province of KwaZulu Natal, South Africa, has found no evidence tha......MORE

Opportunities being missed for a vaginal delivery for HIV-positive pregnant women in Europe with viral suppression

Michael Carter | 5 years ago

There are “missed opportunities” for HIV-positive pregnant women with a suppressed viral load t......MORE

Smoking cannabis does not accelerate progression of liver disease in people with HIV/HCV co-infection

Michael Carter | 5 years ago

Smoking cannabis does not worsen liver disease in people with HIV and hepatitis C virus (HCV) co-in......MORE

Drinking alcohol doesn't increase the risk of HIV treatment failure

Michael Carter | 5 years ago

Alcohol consumption has little impact on key markers used to monitor the health of individuals with......MORE

Investigators identify genetic profile associated with better treatment outcomes in people with HIV/HCV co-infection

Michael Carter | 5 years ago

Several genetic characteristics are associated with a successful response to treatment for hepatiti......MORE

Lymphoma mortality rates remain elevated among HIV-positive people in the United States

Michael Carter | 5 years ago

HIV-positive people in the United States diagnosed with certain types of lymphoma continue to have ......MORE

Biomedical HIV prevention – the social complexities of achieving effectiveness

Roger Pebody | 5 years ago

Public health officials, donors, epidemiologists, researchers and clinicians need to factor in the ......MORE

Only a weak association between immune suppression and increased cardiovascular disease risk for people with HIV

Michael Carter | 5 years ago

There is only a weak association between immune suppression and risk of heart attack and coronary h......MORE

Number of patients diagnosed with HCV in England increased by a third between 2010 and 2012

Michael Carter | 5 years ago

The UK is making progress in the prevention, diagnosis and treatment of hepatitis C virus (HCV), a ......MORE

"Strong" argument for providing HPV vaccination to younger gay men in the UK

Michael Carter | 5 years ago

There is a “strong” argument for extending UK HPV (human papillomavirus) vaccination programmes......MORE

Gay men diagnosed with a rectal STI have a very high risk of subsequent infection with HIV

Michael Carter | 5 years ago

The rate of new HIV infections is especially high among gay men recently diagnosed with a rectal se......MORE

HIV/HCV co-infected people can do well on hepatitis C triple therapy despite contraindications

Liz Highleyman | 5 years ago

Nearly three-quarters of HIV/HCV co-infected patients in the French HEPAVIH cohort achieved end-of-......MORE

What HIV self-testing may mean for couples

Laura Lopez Gonzalez | 5 years ago

A study in Malawi is offering glimpses into why couples opt for HIV self-testing – including issu......MORE

Women with HIV feel 'under surveillance' during pregnancy and early motherhood

Roger Pebody | 5 years ago

Women living with HIV are subject to questioning, monitoring and surveillance of their choices duri......MORE

Many gay men enjoy bareback porn, but are concerned about its possible effects on sexual behaviour

Roger Pebody | 5 years ago

Many gay men who watch pornography enjoy and sometimes prefer material in which condoms are not use......MORE

Medical male circumcision campaigns face cultural challenges in southern Africa

Laura Lopez Gonzalez | 5 years ago

Campaigns to circumcise tens of thousands of men in southern Africa are falling victim to lingering......MORE

Genetic testing lowers risk of nevirapine skin rash

Liz Highleyman | 5 years ago

Screening for genetic mutations could substantially reduce the risk of hypersensitivity reactions i......MORE

Vaccination could prevent infection with anal cancer-associated HPV strains in older gay men

Michael Carter | 5 years ago

A large number of infections with anal cancer-associated strains of human papillomavirus (HPV) amon......MORE

Male circumcision: the message is catching on, but scale-up poses monitoring and follow-up problems

Gus Cairns | 5 years ago

Programmes offering voluntary medical male circumcision (VMMC) as part of HIV prevention are now st......MORE

Six in ten European gay men have had unprotected sex in the past year – more common with steady partners

Roger Pebody | 5 years ago

Across Europe, 58% of gay and other men who have sex with men (MSM) report at least one incident of......MORE

South African couples living with HIV are missing out on safer conception advice

Laura Lopez Gonzalez | 5 years ago

Clinicians and counsellors may understand the right of people living with HIV to have children, but......MORE

Text messages to mothers improve early infant HIV diagnosis rates in Kenya and Mozambique

Carole Leach-Lemens | 5 years ago

Use of text messaging significantly improved the rate of early infant diagnosis (EID) among HIV-pos......MORE

'Option B+' women are at increased risk of loss to follow-up after starting HIV treatment

Lesley Odendal | 5 years ago

Women who begin HIV treatment during pregnancy, or while breastfeeding, prior to the CD4 cell thres......MORE

Kidney problems linked to tenofovir use, improve with switch to abacavir

Liz Highleyman | 5 years ago

Indian people with HIV taking tenofovir had a higher rate of kidney impairment than westerners, acc......MORE

Stigma, delay and misunderstanding slow access to ART in Africa

Gus Cairns | 5 years ago

Three presentations at the recent 7th International AIDS Society conference on HIV Pathogenesis, T......MORE

Scientists and clinicians must challenge HIV-related stigma and ensure enabling legal and policy environments, IAS conference hears

Edwin J. Bernard | 5 years ago

Scientists should not only create knowledge to improve the HIV epidemic, they also have a duty to s......MORE

Efavirenz in children: WHO dosing guidelines raise the risk of side-effects in Thai children

Carole Leach-Lemens | 5 years ago

Taking efavirenz according to 2010 World Health Organization (WHO) guidelines ensures a higher prop......MORE

Non-African middle-income countries pay four times more for ARVs than African middle-income countries

Lesley Odendal | 5 years ago

Middle-income countries outside Africa are paying, on average, four times more for antiretrovirals ......MORE

Darunavir/ritonavir safe and effective for younger children

Carole Leach-Lemens | 5 years ago

Over 80% of treatment-experienced children with HIV aged three to six years from ten sites in Argen......MORE

Lower-dose lopinavir/ritonavir reduces side-effects, maintains viral control in Thai children

Carole Leach-Lemens | 5 years ago

Low dose lopinavir/ritonavir (LPV/r) – 70% of the standard dose – worked as well as standard do......MORE

Magical thinking? FEM-PrEP trial may have failed because participants used testing as prevention

Gus Cairns | 5 years ago

While the 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (......MORE

Malaysia’s harm reduction programmes are preventing infections and saving money, but reaching far too few people who inject drugs

Roger Pebody | 5 years ago

An expansion of methadone maintenance and needle exchange programmes in Malaysia, a conservative Mu......MORE

Fibroscan accurately predicts liver decompensation and death in HIV/HCV co-infected people

Liz Highleyman | 5 years ago

The non-invasive transient elastometry method of estimating liver damage may be a better way to pre......MORE

Studies look at bone changes during second-line therapy, fractures, and HIV- and HCV-related bone loss

Liz Highleyman | 5 years ago

People with HIV experience less bone loss if they switch to a NRTI-sparing second-line regimen cont......MORE

Strategies to detect and treat MSM with acute infection may be a powerful tool to control HIV epidemics

Roger Pebody | 5 years ago

The detection and control of acute (very recent) HIV infection may be a powerful HIV prevention mea......MORE

Long-acting GSK1265744 and TMC278-LA appear safe and practical in early study

Liz Highleyman | 5 years ago

A combination of antiretroviral drugs in long-acting nanosuspension formulations achieved adequate ......MORE

No increase in risk behaviour in people taking antiretroviral therapy, meta-analysis shows

Roger Pebody | 5 years ago

One of the anxieties in relation to ‘treatment as prevention’ is that it may discourage people ......MORE

First-line antiretroviral therapy has improved over time, meta-analysis shows

Liz Highleyman | 5 years ago

The effectiveness of initial antiretroviral treatment has improved markedly over the years, but man......MORE

Intervention with cash lottery prizes cuts HIV infection by 39% in young women in Lesotho

Roger Pebody | 5 years ago

An HIV prevention intervention in which young people who had tested negative for sexually transmitt......MORE

Ambitious plans for treatment as prevention in Asia, but challenges remain

Roger Pebody | 5 years ago

Countries such as China, Cambodia and Vietnam have made strong commitments to curbing their HIV epi......MORE

Dolutegravir superior to raltegravir for treatment-experienced people with HIV

Liz Highleyman | 5 years ago

The once-daily HIV integrase inhibitor dolutegravir demonstrated better efficacy than twice-daily r......MORE

Reduced efavirenz dose suppresses HIV as well as standard dose

Liz Highleyman | 5 years ago

Lowering the dosage of efavirenz (Sustiva or Stocrin) from 600 to 400mg in an antiretroviral regime......MORE

Study supports WHO recommendations for second-line HIV therapy in resource-limited countries

Liz Highleyman | 5 years ago

A second-line regimen consisting of a protease inhibitor (PI) plus two nucleoside/nucleotide revers......MORE

Bangkok PrEP study finds PrEP efficacy is related to drug exposure

Gus Cairns | 5 years ago

The 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention heard ......MORE

PrEP appears safe for use in conception, but may not be necessary if partner is taking treatment

Roger Pebody | 5 years ago

HIV-negative women who wish to become pregnant with their male HIV-positive partner can be reassure......MORE

First-ever community-randomised combination prevention trial produces modest drop in HIV incidence, big increase in testing in men

Gus Cairns | 5 years ago

The results of a pioneering HIV prevention trial comparing the effects of mobile HIV testing, commu......MORE

Two stem cell transplant recipients now controlling HIV off treatment

Keith Alcorn | 5 years ago

Two people with HIV who received stem cell transplants for the treatment of lymphoma are now contro......MORE

How can most-at-risk populations be encouraged to seek HIV testing?

Lesley Odendal | 5 years ago

Peer-mediated HIV counselling resulted in the highest uptake of HIV counselling and testing (HCT) a......MORE

Kick, kill, contain – researchers examine three possible steps in a cure for HIV

Gus Cairns | 5 years ago

The  7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS ......MORE

Starting treatment at a CD4 count above 500 reduces the HIV reservoir for people with long-term infection

Keith Alcorn | 5 years ago

People with HIV who start treatment with CD4 counts above 500, after the first phase of primary inf......MORE

Home visits during pregnancy increase number of male partners tested for HIV

Roger Pebody | 5 years ago

A randomised controlled trial in Kenya has found that home visits immediately after a woman’s app......MORE

German researchers report case of 'functional cure' after very early HIV treatment

Keith Alcorn | 5 years ago

Another case of prolonged control of HIV replication after stopping treatment was reported on Tuesd......MORE

AbbVie interferon-free hepatitis C combo works well with reduced ribavirin dose

Liz Highleyman | 5 years ago

People taking hepatitis C treatment who reduced their dose of ribavirin due to side-effects neverth......MORE

Experts discuss role of drug policy in HIV, hepatitis and TB epidemics

Liz Highleyman | 5 years ago

International drug policy must shift from prohibition to public health in order to reduce harms to ......MORE

High linkage to care after community-based HIV counselling and testing in South Africa associated with confidence in drug supplies, depression

Lesley Odendal | 5 years ago

Believing that drugs and supplies are generally available at the local health facility and experien......MORE

Hepatitis C reinfection occurs frequently among gay men living with HIV in London

Michael Carter | 5 years ago

There is a high incidence of hepatitis C virus (HCV) reinfection among gay men living with HIV in L......MORE

New recommendations on HIV treatment for children require earlier diagnosis, new drug combinations for maximum impact

Keith Alcorn | 5 years ago

New World Health Organization (WHO) guidelines recommending antiretroviral treatment for all childr......MORE

Turning surveillance into support for men who have sex with men in Africa

Gus Cairns | 5 years ago

We need to stop simply doing research into the health and behaviours of gay men and other men who h......MORE

High positivity rate and good linkage to care at Barcelona community testing project

Roger Pebody | 5 years ago

A single community testing site is testing over a third of the gay men newly diagnosed with HIV in......MORE

Management of age-related conditions is 'the future of HIV care', says IAS conference keynote speaker

Liz Highleyman | 5 years ago

Other diseases are becoming far more important than AIDS for people with HIV who have consistent ac......MORE

Cure research is new phase of HIV therapy, says US AIDS chief

Keith Alcorn | 5 years ago

“We are at the earliest dawn of a new stage of HIV therapy” said Carl Dieffenbach, director of ......MORE

WHO issues new HIV recommendations calling for earlier ARV initiation

Lesley Odendal | 5 years ago

New HIV treatment guidelines by the World Health Organization (WHO) launched today at the 7th Inte......MORE

People with HIV outside continuous care contribute disproportionately to viral load and infection potential, Canadian study finds

Gus Cairns | 5 years ago

A study from Calgary in Canada has found that people who were in continuous care for a year, althou......MORE

Fear of future health problems encourage people to start and complete HCV therapy but concern about side-effects is a deterrent

Michael Carter | 5 years ago

US research has provided important insights into the factors that motivate and deter people from st......MORE

Knowledge gaps, problems accessing services for MSM in several countries of eastern and south-eastern Europe

Roger Pebody | 5 years ago

A substantial minority of men who have sex with men (MSM) in countries such as Cyprus, Serbia, Lith......MORE

Kaletra monotherapy achieves 'satisfactory' levels of HIV suppression during pregnancy

Michael Carter | 5 years ago

Kaletra (lopinavir/ritonavir) monotherapy achieves satisfactory levels of virological suppression i......MORE

Home-based counselling and testing with point-of-care CD4 counts maximises linkage to care in rural South Africa

Carole Leach-Lemens | 5 years ago

Home-based testing and counselling (HBCT), combined with same day point-of-care CD4 testing and lay......MORE

European gay men more likely to buy or sell sex if they have large numbers of sex partners, are lonely and use drugs

Michael Carter | 5 years ago

Results of a large European internet-based survey show that 8% of gay and other men who have sex wi......MORE

Antiretroviral therapy cuts mortality risk for people diagnosed with HIV-related lymphoma

Michael Carter | 5 years ago

Higher cumulative viral load in the six months after diagnosis with HIV-related lymphoma is associa......MORE

Sex while abroad contributing to ongoing HIV and STI epidemics in European gay men

Michael Carter | 5 years ago

Sex while abroad appears to be contributing to the ongoing epidemics of HIV and other sexually tran......MORE

Elevated prevalence of HIV and STIs among migrant gay men in Europe

Michael Carter | 5 years ago

Migrant gay and other men who have sex with men (MSM) have a higher prevalence of HIV and sexually ......MORE

New prevention strategies will only be implemented if they are tailored to local contexts and cultures

Roger Pebody | 5 years ago

While clinical trials have demonstrated the efficacy of treatment as prevention, pre-exposure proph......MORE

ARV and TB medicine drug supply issues threaten South Africa’s ARV programme

Lesley Odendal | 5 years ago

HIV activist groups in South Africa are calling on the Minister of Health to address drug supply c......MORE

Interaction between steroid injections and HIV protease inhibitors can disrupt cortisol levels

Michael Carter | 5 years ago

Corticosteroid injections can lead to dysfunctions in cortisol levels in people taking HIV protease......MORE

Prompt HIV diagnosis and early antiretroviral therapy especially important for older people

Michael Carter | 5 years ago

Prompt HIV diagnosis and early antiretroviral therapy are especially important for older people, re......MORE

Over half of people living with AIDS in San Francisco are aged 50 or older

Michael Carter | 5 years ago

Over half of people living with an AIDS diagnosis in San Francisco are aged 50 or older, investigat......MORE

Hyaluronic acid levels can predict risk of serious liver events in people living with HIV and hepatitis B or C co-infection

Michael Carter | 5 years ago

A simple blood test can predict the risk of liver-related death or hepatic encephalopathy for peopl......MORE

PrEP works for injecting drug users too

Roger Pebody | 5 years ago

A daily tablet of tenofovir, a drug otherwise used to treat HIV infection, reduced the risk of HIV ......MORE

Sexual health information is often inappropriate for Facebook sharing, say young people

Roger Pebody | 5 years ago

Sexual health promoters who wish to harness the power of Facebook and other social media need to co......MORE

Low CD4 cell count increases the risk of several cancers after starting HIV therapy

Michael Carter | 5 years ago

A large US study has provided important new insights into the incidence and timing of cancers among......MORE

Mobile phone support increases chances that people living with HIV will quit smoking

Michael Carter | 5 years ago

Smoking cessation support delivered via mobile phones increases chances that people living with HIV......MORE

Undetectable viral load reduces the risk of HIV-associated anal cancer

Michael Carter | 5 years ago

HIV therapy that effectively controls viral load reduces the risk of anal cancer, US research publi......MORE

High rate of spontaneous disease regression in men with high-grade pre-cancerous anal lesions

Michael Carter | 5 years ago

High-grade pre-cancerous anal lesions are more likely to regress than progress, according to Austra......MORE

Intimate partner violence associated with subsequent HIV infection in Uganda

Roger Pebody | 5 years ago

Ugandan women who have been subject to violence from a sexual partner are more likely than other wo......MORE

Combination prevention could "eliminate" HIV transmissions in Vietnam, model projects

Michael Carter | 5 years ago

A “combination prevention” strategy with targeted HIV testing and early antiretroviral therapy ......MORE

Female sex workers frequently offered larger fees by their clients in return for sex without a condom

Michael Carter | 5 years ago

Client demand for unprotected sex is contributing to the HIV epidemic among female sex workers, acc......MORE

High rates of gonorrhoea among people living with HIV in the US

Michael Carter | 5 years ago

Combining HIV and gonorrhoea surveillance databases has revealed a high prevalence of gonorrhoea am......MORE

2012: half a million sexually transmitted infections in England

Roger Pebody | 5 years ago

There were just under half a million new diagnoses of sexually transmitted infections (STIs) in 201......MORE

People doing well on HIV therapy have a mortality risk identical to that of HIV-negative peers

Michael Carter | 5 years ago

HIV-positive people taking antiretroviral therapy who have an undetectable viral load and a CD4 cel......MORE

Campaign approach increases enrolment of pregnant women on ART in South Africa

Keith Alcorn | 5 years ago

A targeted campaign among health workers, using quality-improvement (QI) health system methods, can......MORE

Campaign approach increases enrolment of pregnant women on ART in South Africa

Carole Leach-Lemens | 5 years ago

A targeted campaign among health workers, using quality-improvement (QI) health system methods, can......MORE

Nevirapine dose escalation for children may risk treatment failure

Carole Leach-Lemens | 5 years ago

Full-dose nevirapine should be considered for HIV-positive children under two years of age in Afric......MORE

Community viral load is flawed indicator of infectiousness, say experts

Gus Cairns | 5 years ago

Four US researchers from the University of Chapel Hill in North Carolina, including Myron Cohen, pr......MORE

HIV cure: the long road ahead

Keith Alcorn | 5 years ago

Scientists from around the world met to review the future of HIV scientific research at the Institu......MORE

'War on drugs' fuelling the hepatitis C epidemic among people who inject drugs

Michael Carter | 5 years ago

The global war on drugs has had a disastrous impact on the hepatitis C epidemic, a new report from ......MORE

Deciding what’s risky – Australian gay men pay more attention to the sexual act than to their partner’s HIV status or viral load

Roger Pebody | 5 years ago

HIV-negative gay men in Sydney, Australia perceive the risk of HIV transmission to be different in ......MORE

Hepatitis C treatment gap in Europe: France doing well but Italy treated fewer than one in a hundred patients in 2010

Keith Alcorn | 5 years ago

France led the world in the proportion of its hepatitis C patients who received treatment in 2010, ......MORE

Small fall in new HIV diagnoses in London, but rate of new diagnoses among gay men continues to increase

Michael Carter | 5 years ago

There was a modest fall in the number of new HIV diagnoses in London in 2011, new figures show. A t......MORE

Expanded access to HIV treatment achieves big falls in mortality rates in China

Michael Carter | 5 years ago

Mortality rates fell sharply among people receiving antiretroviral therapy in China between 2003 an......MORE

AZT associated with poorer immunological recovery in people taking first-line HIV treatment in southern Africa

Michael Carter | 5 years ago

AZT-based antiretroviral therapy is associated with lower increases in CD4 cell counts than other H......MORE

Majority of Italian HIV specialists would prescribe PrEP

Gus Cairns | 5 years ago

Seventy per cent of Italian HIV specialists who answered an online survey would prescribe pre-expos......MORE

Case workers can re-engage a high proportion of HIV-positive people lost to long-term care

Michael Carter | 5 years ago

Caseworkers helped 50% of HIV-positive people in New York City who had dropped out of care re-engag......MORE

Higher rates of HIV in US black gay men may be due to smaller choice of partners and more age mixing

Gus Cairns | 5 years ago

Limited partner choice, wider age gaps between partners, and mistaken beliefs about HIV status in r......MORE

Dramatic improvements in HIV testing are possible – local leadership and multiple initiatives required

Roger Pebody | 5 years ago

In Brighton & Hove the proportion of new HIV diagnoses which are made outside of sexual health and ......MORE

Triple therapy for hepatitis C is effective after liver transplantation, but side-effects are common

Liz Highleyman | 5 years ago

Adding the approved HCV protease inhibitor telaprevir (Incivo or Incivek) to pegylated interferon ......MORE

Engagement with health care leads to more prompt HIV diagnosis and higher rates of virological suppression among gay men

Michael Carter | 5 years ago

Pre-existing connection with primary health care is associated with more prompt diagnosis of HIV in......MORE

Hepatitis E virus infection can cause rapid liver cirrhosis in people with HIV who have low CD4 cell counts

Michael Carter | 5 years ago

Infection with hepatitis E virus (HEV) can cause rapid liver fibrosis in people with HIV who have l......MORE

More drugs, more alcohol often means more risky sex for HIV-negative gay men

Michael Carter | 5 years ago

There is a highly significant relationship between frequency and intensity of drug and alcohol use ......MORE

People more likely to keep HIV clinic appointments if they believe their care providers know them as a person

Michael Carter | 5 years ago

People who believe their care providers know them as a person are more likely to keep their HIV cli......MORE

New HCV combinations could have a big role in prevention, but only if treatment rates increase

Michael Carter | 5 years ago

New combinations of hepatitis C drugs could have major public health benefits, a modelling study pu......MORE

Up to a third of HIV infections in European gay men may have come from another country

Gus Cairns | 5 years ago

A study (Frentz) that looked at genetic similarities in the HIV from recently diagnosed people in 2......MORE

Movement for global access to hepatitis C treatment building momentum

Keith Alcorn | 5 years ago

Access to hepatitis C treatment in low- and middle-income countries is being restricted by the hig......MORE

Herpes viruses associated with shedding of HIV in the semen of gay men taking suppressive antiretroviral therapy

Michael Carter | 5 years ago

Low level HIV replication in semen persists in almost 10% of gay men taking antiretroviral therapy,......MORE

Report highlights major failings in UK response to hepatitis C

Michael Carter | 5 years ago

The UK needs to “be doing so much more” in response to hepatitis C, according to a new report. ......MORE

High prevalence of oral HPV infection in Dutch gay men

Michael Carter | 5 years ago

Oral infection with human papillomavirus (HPV) is common among gay men, Dutch investigators report ......MORE

Daclatasvir + asunaprevir + BMS-791352 looks promising as interferon-free combination

Liz Highleyman | 5 years ago

An all-oral regimen containing three next-generation antivirals taken for either 12 or 24 weeks pro......MORE

Blackmail, violence and stigma restrict access to sexual health services for gay men, Global Health and Rights Study reports

Gus Cairns | 5 years ago

The Global Forum for MSM and HIV has released an analysis of its 2012 Global Men’s Health and Rig......MORE

Compassionate access to new hepatitis C drugs an "emergency" for European patients

Keith Alcorn | 5 years ago

European governments must move quickly to ensure that compassionate use arrangements are put into p......MORE

Second-generation protease inhibitor faldaprevir cures up to 80% of hepatitis C

Keith Alcorn | 5 years ago

A second-generation hepatitis C protease inhibitor, faldaprevir, cured up to 80% of previously untr......MORE

Second-generation HCV protease inhibitor simeprevir pushes triple therapy cure rate up to 80%

Keith Alcorn | 5 years ago

A second-generation hepatitis C protease inhibitor, simeprevir, cured around 80% of previously untr......MORE

Triple-drug HCV therapy comes with high risk of serious adverse events for people with cirrhosis

Keith Alcorn | 5 years ago

Currently available triple therapies for hepatitis C carry a high risk of serious side-effects for ......MORE

Hep C quad regimens quashed, but some components go forward

Liz Highleyman | 5 years ago

A pair of four-drug interferon-based hepatitis C regimens worked well, but further study has been h......MORE

Daclatasvir + sofosbuvir offers hepatitis C rescue therapy after current standard of care

Liz Highleyman | 5 years ago

An interferon-free regimen of daclatasvir plus sofosbuvir, with or without ribavirin, cured all pre......MORE

A majority of HIV-positive gay men in Dutch survey take their viral load into consideration if having unprotected sex

Gus Cairns | 5 years ago

About 40% of men who answered a community survey for HIV-positive gay men in the Netherlands said t......MORE

Researchers stop the only current HIV vaccine efficacy trial

Gus Cairns | 5 years ago

The US National Institute of Allergy and Infectious Diseases (NIAID) has announced that it is disco......MORE

AbbVie interferon-free combination cures over 90% of hepatitis C genotype 1

Keith Alcorn | 5 years ago

A four-drug combination of direct acting antivirals developed by AbbVie cured hepatitis C infection......MORE

Sofosbuvir + ribavirin cures most genotype 2 hepatitis C, but genotype 3 response is lower

Liz Highleyman | 5 years ago

A dual oral regimen containing the hepatitis C nucleotide polymerase inhibitor sofosbuvir plus rib......MORE

Consistent decline in partner numbers in US gay men in last decade, but no change in condom use

Gus Cairns | 5 years ago

Data from two national sex surveys in the United States show that gay and bisexual men (men who hav......MORE

Genetics make a large contribution to cardiovascular risk for people with HIV

Michael Carter | 5 years ago

Genetic background has a major impact on the risk of coronary artery disease for people with HIV, r......MORE

For African women in the UK, formula feeding has a high social and personal cost

Roger Pebody | 5 years ago

Although most African women living with HIV in the UK do comply with medical recommendations to avo......MORE

Some barriers to adherence for black African people in London are culturally specific

Roger Pebody | 5 years ago

Qualitative research suggests that some of the barriers to antiretroviral adherence for black Afric......MORE

London HIV drug prescribing changes – patient satisfaction and clinical outcomes maintained

Roger Pebody | 5 years ago

Controversial changes to the range of anti-HIV drugs which are most commonly prescribed in London h......MORE

Training for GPs can increase HIV testing rate

Roger Pebody | 5 years ago

A multifaceted educational intervention for doctors and practice nurses working in general practice......MORE

Elevated prevalence of HIV and viral hepatitis in men injecting anabolic steroids

Roger Pebody | 5 years ago

Addressing a topic that has received remarkably little research attention over the years, Dr Vivian......MORE

England: Health & Wellbeing Boards not prioritising HIV

Roger Pebody | 5 years ago

In areas of high HIV prevalence in England, half the local authorities have not made HIV a public h......MORE

England: health and wellbeing boards not prioritising HIV

Roger Pebody | 5 years ago

In areas of high HIV prevalence in England, half the local authorities have not made HIV a public h......MORE

Integrating HIV care into community health workers' role is a good model for southern Africa

Carole Leach-Lemens | 5 years ago

A community health worker model of home-based preventive care, the Philani Intervention Program (PI......MORE

South African clinics already achieving zero new HIV infections in children

Carole Leach-Lemens | 5 years ago

Maternity clinics in South Africa have the potential to achieve zero transmission of HIV from mothe......MORE

South African clinics already achieving zero new HIV infections in children

Keith Alcorn | 5 years ago

Maternity clinics in South Africa have the potential to achieve zero transmission of HIV from mothe......MORE

Liver disease a major cause of illness and death across the EU: action needed to save lives

Michael Carter | 5 years ago

Liver disease is the cause of a considerable burden of illness across the European Union (EU), inve......MORE

Life expectancy for South African patients who start HIV therapy with CD4 cell counts above 200 is 'near normal'

Michael Carter | 5 years ago

HIV-positive patients in South Africa can have a near-normal life expectancy, provided that they st......MORE

PrEP doesn't lead to increases in risky sex among gay men

Michael Carter | 5 years ago

Taking HIV pre-exposure prophylaxis (PrEP) does not lead to increased levels of sexual risk behavio......MORE

CMV replication associated with increased mortality risk in Thai patients starting HIV therapy

Michael Carter | 5 years ago

Ongoing cytomegalovirus (CMV) replication is associated with an increased mortality risk for people......MORE

Treating everyone diagnosed would not end HIV in US gay men, Los Angeles-based model finds

Gus Cairns | 5 years ago

Increasing HIV testing frequency, and giving everyone antiretroviral therapy (ART), would not in th......MORE

Viral load in genital secretions differs between men and women undergoing HIV therapy

Michael Carter | 5 years ago

The female genital tract appears to be a 'reservoir' for ongoing HIV replication, even during effec......MORE

No increase in sexual risk taking by gay men in England, 2001 to 2008

Roger Pebody | 5 years ago

Analysis of Gay Men’s Sex Survey data shows that, overall, the proportion of men reporting unprot......MORE

Hepatitis C epidemic in US gay men is decades old

Michael Carter | 5 years ago

Hepatitis C virus (HCV) transmissions have been occurring in gay men since at least the early years......MORE

One-in-four deaths in pregnancy due to HIV in worst-affected countries

Carole Leach-Lemens | 5 years ago

One-in-four pregnancy-related deaths is due to HIV in countries with a high HIV prevalence, a meta-......MORE

Marriage is a risk factor for HIV infection in Malawi

Roger Pebody | 5 years ago

Marriages in Malawi are characterised by such stark gender inequalities that marriage itself is a r......MORE

Disagreements about agreements – many gay couples lack clarity on sex outside their relationship

Roger Pebody | 5 years ago

The majority of American gay men in relationships say they establish a ‘sexual agreement’ with ......MORE

Concentrations of HIV protease inhibitors increase with age

Michael Carter | 5 years ago

Plasma concentrations of protease inhibitors increase with age, investigators from the United Kingd......MORE

Review shows HIV self-testing to be acceptable, accurate and feasible, but finds little data on linkage to care for those testing HIV-positive

Michael Carter | 5 years ago

Self-testing for HIV is highly acceptable to patients in a variety of settings, investigators repor......MORE

Review shows HIV self-testing to be acceptable, accurate and feasible, but finds little data on linkage to care for those testing HIV positive

Michael Carter | 5 years ago

Self-testing for HIV is highly acceptable to people in a variety of settings, investigators report ......MORE

KS-associated IRIS common among people starting HIV therapy in Africa

Michael Carter | 5 years ago

Over 13% of people with HIV-related Kaposi’s sarcoma experience a worsening of disease after star......MORE

Tenofovir and 3TC prevent new hepatitis B infections in gay men living with HIV

Michael Carter | 5 years ago

The inclusion of 3TC or tenofovir in antiretroviral treatment regimens reduces the risk of infectio......MORE

Drinking coffee halves the risk of liver cancer

Michael Carter | 5 years ago

Coffee consumption reduces the risk of liver cancer by approximately 50%, the results of a meta-ana......MORE

Very high incidence of high-grade pre-cancerous anal lesions among young HIV-positive Thai gay men

Michael Carter | 5 years ago

Approximately a third of HIV-positive gay men in Thailand developed high-grade pre-cancerous anal l......MORE

Long-term suppression of viral load and sustained CD4 cell increase reduce risk of cervical HPV infection for HIV-positive women

Michael Carter | 5 years ago

HIV therapy that achieves long-term suppression of viral load and sustained immune reconstitution r......MORE

Recruitment through social networks is an efficient way to increase demand for HIV testing among high-risk groups

Roger Pebody | 5 years ago

A pilot project which used a peer recruitment strategy, financial incentives and the involvement of......MORE

Almost three-quarters of people starting HIV therapy in Tanzania have dyslipidemia after three years of treatment

Michael Carter | 5 years ago

Approximately 75% of HIV-positive patients in Tanzania had lipid abnormalities three years after st......MORE

Point-of-care viral load testing potentially cost-effective in southern Africa

Carole Leach-Lemens | 5 years ago

Routine point-of-care viral load (POC-VL) tests with detection limits of 1000 copies/ml or below wi......MORE

Meta-analysis shows the massive global burden of HIV among transgender women

Michael Carter | 5 years ago

Almost a fifth of transgender women worldwide are infected with HIV, results of a meta-analysis pub......MORE

Sexual transmission of hepatitis C very rare in monogamous heterosexual couples

Michael Carter | 5 years ago

Sexual transmission of hepatitis C virus (HCV) among monogamous heterosexual couples is extremely r......MORE

Quality of health services is key in encouraging or discouraging people from HIV testing in Africa

Roger Pebody | 5 years ago

The uptake of HIV testing in sub-Saharan Africa is influenced by the quality and manner in which h......MORE

Steroids reduce mortality risk for people taking TB treatment

Michael Carter | 5 years ago

Corticosteroid treatment is associated with a reduced risk of mortality for people taking tuberculo......MORE

People doing well on HIV therapy "should be eligible" for life insurance cover

Michael Carter | 5 years ago

The long-term effectiveness of antiretroviral therapy means that many HIV-positive people should be......MORE

Self-testing and home treatment initiation triples uptake of HIV treatment in Malawi

Keith Alcorn | 5 years ago

Offering people the opportunity to self-test at home and then start antiretroviral therapy after co......MORE

Routine tests prompted by electronic patient records increase rates of STI diagnoses among HIV-positive people in London

Michael Carter | 5 years ago

The implementation of systematic, frequent and routine screening for sexually transmitted infection......MORE

Sofosbuvir plus ribavirin works well for hard-to-treat inner-city hepatitis C patients

Liz Highleyman | 5 years ago

A simple 24-week oral regimen consisting of sofosbuvir plus full-dose ribavirin cured nearly 70% of......MORE

AbbVie interferon-free combinations cure most newly treated hepatitis C patients

Liz Highleyman | 5 years ago

All-oral regimens consisting of the HCV protease inhibitor ABT-450, a non-nucleoside polymerase inh......MORE

Lukewarm reaction to government’s sexual health framework for England

Roger Pebody | 5 years ago

Just two weeks before local authorities take over the commissioning of sexual health services – a......MORE

HIV increases the risk of heart attack, even in people with a suppressed viral load

Michael Carter | 5 years ago

Infection with HIV is associated with an increased risk of heart attack, investigators from the Uni......MORE

Even moderate alcohol consumption increases risk of death for people with chronic hepatitis C

Michael Carter | 5 years ago

Moderate alcohol consumption - as little as one or two drinks per day -  is associated with an inc......MORE

French researchers report 14 patients in 'remission' after controlling HIV for over 4 years off treatment

Gus Cairns | 5 years ago

Two weeks ago, the announcement that a baby had been ‘functionally cured’ of HIV disease with t......MORE

Are we underestimating the proportion of virally-suppressed patients in the US?

Gus Cairns | 5 years ago

Several presentations at the recent 20th Conference on Retroviruses and Opportunistic Infections in......MORE

Lopinavir/ritonavir equivalent to nevirapine in Ugandan children

Carole Leach-Lemens | 5 years ago

A ritonavir-boosted lopinavir (LPV/r)-based regimen achieved a comparable rate of virologic suppres......MORE

Gene therapy studies show potential for HIV control without drugs

Gus Cairns | 5 years ago

Gene therapy approaches that involve the genetic modification of human haematopoietic stem cells ha......MORE

Adding telaprevir improves acute hepatitis C treatment for HIV-positive men

Liz Highleyman | 5 years ago

Adding telaprevir (Incivo or Incivek) to pegylated interferon and ribavirin shortens the duration o......MORE

Simeprevir & sofosbuvir demonstrates good early cure rate with or without ribavirin

Liz Highleyman | 5 years ago

An all-oral combination of simeprevir plus sofosbuvir, with or without ribavirin, led to an early c......MORE

Malawi achieves seven-fold increase in ART for pregnant and breastfeeding women

Carole Leach-Lemens | 5 years ago

Eighteen months after implementation of 'Option B+' in Malawi – ART for life for all HIV-infected......MORE

Routine viral load monitoring almost halves risk of virologic failure in 18-month Kenyan study

Lesley Odendal | 5 years ago

Six-monthly viral load testing of patients taking antiretroviral therapy (ART) at primary health cl......MORE

Faldaprevir ups interferon response in HIV/HCV co-infection

Liz Highleyman | 5 years ago

Adding the hepatitis C virus (HCV) protease inhibitor faldaprevir (formerly BI 201335) to pegylated......MORE

Simeprevir pushes HCV cure rate above 75% for HIV/HCV co-infection

Liz Highleyman | 5 years ago

Adding the new hepatitis C virus (HCV) protease inhibitor simeprevir (formerly TMC435) to pegylated......MORE

Contraceptive injections and HIV infection risk – a public health conundrum

Roger Pebody | 5 years ago

The concerns about a possible increase in risk of HIV acquisition with some hormonal contraceptive ......MORE

New integrase inhibitor dolutegravir helps treatment-experienced people on failing therapy

Liz Highleyman | 5 years ago

The next-generation integrase inhibitor dolutegravir proved more beneficial than raltegravir (Isent......MORE

Second-line NRTI-sparing regimen proves equally effective for resource-limited settings

Keith Alcorn | 5 years ago

A second-line antiretroviral regimen of lopinavir/ritonavir (Kaletra/Aluvia) and raltegravir (Isent......MORE

Can people with resistant HIV omit NRTIs when switching from a failing regimen?

Liz Highleyman | 5 years ago

Omitting nucleoside reverse transcriptase inhibitors (NRTIs) when switching from a non-suppressive ......MORE

New pro-drug tenofovir alafenamide appears equally effective but better tolerated

Liz Highleyman | 5 years ago

Tenofovir alafenamide fumarate or TAF (formerly GS-7340), a new pro-drug of the widely used NRTI te......MORE

Slow progress in expansion of voluntary circumcision coverage

Gus Cairns | 5 years ago

Progress towards greater coverage of voluntary male circumcision (MC) in Africa remains slow, and i......MORE

Dosing of key TB drug rifampicin could go higher

Keith Alcorn | 5 years ago

Rifampicin, a key drug in tuberculosis (TB) treatment, can be tolerated at much higher doses than u......MORE

Once-weekly continuation phase TB treatment equals standard of care

Keith Alcorn | 5 years ago

A new two-drug combination of rifapentine and moxafloxacin can allow tuberculosis (TB) treatment to......MORE

UK healthcare workers need better information and guidance on HIV criminalisation

Roger Pebody | 5 years ago

Support services for people living with HIV would benefit from better information and support aroun......MORE

Dually active antiretroviral therapy protects against hepatitis B infection

Liz Highleyman | 5 years ago

Use of antiretroviral therapy that includes drugs active against both hepatitis B virus (HBV) and H......MORE

Dually active antiretroviral therapy protects against hepatitis B infection

Keith Alcorn | 5 years ago

Use of antiretroviral therapy that includes drugs active against both hepatitis B virus (HBV) and H......MORE

Continuing cotrimoxazole in children on ART reduces the risk of hospitalisation

Carole Leach-Lemens | 5 years ago

Children on ART for more than two years who continued taking daily cotrimoxazole had significantly ......MORE

Black gay men run higher risk of HIV infection despite fewer partners

Gus Cairns | 5 years ago

An analysis of four studies of sexual risk and HIV infection in US gay men, presented at the 20th C......MORE

New NNRTI MK-1439 shows promise in early clinical trial

Liz Highleyman | 5 years ago

A next-generation non-nucleoside reverse transcriptase inhibitor (NNRTI), MK-1439, demonstrated rob......MORE

Dual CCR5/CCR2 inhibitor cenicriviroc has anti-inflammatory as well as anti-HIV effect

Liz Highleyman | 5 years ago

Cenicriviroc, which blocks both CCR5 and CCR2 receptors on immune cells, is effective against HIV, ......MORE

Small risk of neurological birth defects due to efavirenz confirmed in French cohort

Keith Alcorn | 5 years ago

A large French study has found an elevated risk of some birth defects in children born to women exp......MORE

HIV treatment for children is safe and highly effective without laboratory monitoring in large African trial

Keith Alcorn | 5 years ago

Children did just as well on antiretroviral therapy without routine laboratory monitoring of CD4 ce......MORE

French studies report real-world data on use of telaprevir and boceprevir in people with HIV and hepatitis C co-infection

Liz Highleyman | 5 years ago

Adding boceprevir or telaprevir to interferon-based therapy showed promising indications of efficac......MORE

Very early antiretroviral treatment limits the size of HIV reservoir

Keith Alcorn | 5 years ago

Very early antiretroviral treatment may limit the size of the HIV reservoir in adults and children,......MORE

Sofosbuvir/ledipasvir/ribavirin cures 100% of genotype 1 hepatitis C patients

Liz Highleyman | 5 years ago

An interferon-free regimen containing sofosbuvir (formerly GS-7997), ledipasvir (formerly GS-5885)......MORE

Consistent condom use in anal sex stops 70% of HIV infections, study finds, but intermittent use has no effect

Gus Cairns | 5 years ago

An analysis by Dawn Smith of the US Centers for Disease Control (CDC) reported at the 20th Confere......MORE

Monthly injectable drug offers 100% protection against HIV in monkeys – could be dosed every three months

Gus Cairns | 5 years ago

An injectable, long-lasting integrase inhibitor drug, when given to rhesus macaques exposed to a mo......MORE

VOICE trial's disappointing result poses big questions for PrEP

Gus Cairns | 5 years ago

The failure of one of the largest trials yet conducted of HIV drug-based prevention methods poses q......MORE

Case report of a 'functional' HIV cure in a child

Keith Alcorn | 5 years ago

Researchers in the United States today said that they have identified a case of a 'functional' HIV......MORE

US gay youth PrEP study meets recruitment and adherence problems

Gus Cairns | 5 years ago

A small six-month pilot study of the feasibility and acceptability of pre-exposure prophylaxis (PrE......MORE

US gay youth PrEP study meets retention and adherence problems

Gus Cairns | 5 years ago

A small six-month pilot study of the feasibility and acceptability of pre-exposure prophylaxis (PrE......MORE

In resource-rich countries, migrants have a higher risk of progressing to AIDS in the first year of HIV therapy

Michael Carter | 5 years ago

Rates of AIDS-defining illnesses in the first year of antiretroviral therapy are significantly high......MORE

Study shows value of hepatitis C therapy for HIV co-infected patients with compensated cirrhosis

Michael Carter | 5 years ago

Spanish research published in the online edition of Clinical Infectious Diseases shows the benefits......MORE

Meta-analysis shows superiority of integrase inhibitors in first-line HIV therapy and benefits for people changing treatment due to resistance

Michael Carter | 5 years ago

Antiretroviral combinations based on an integrase inhibitor are superior to other first-line HIV tr......MORE

Variations in genital shedding of HIV during menstrual cycle large enough to impact on risk of sexual transmission

Michael Carter | 5 years ago

Genital shedding of HIV varies considerably during the menstrual cycle, investigators report in the......MORE

Low nadir CD4 cell count associated with increased cataract risk in South Africans taking HIV therapy

Michael Carter | 5 years ago

A low nadir (lowest ever) CD4 cell count is associated with increased lens density – a marker for......MORE

Earlier treatment in South African cohort did not increase loss to follow-up

Carole Leach-Lemens | 5 years ago

Implementation of South Africa’s 2011 expansion of treatment guidelines – starting antiretrovir......MORE

Classic characteristics of old age associated with poor physical function in middle-aged people living with HIV

Michael Carter | 5 years ago

Impaired physical function in middle-aged people living with HIV is associated with low reduced mus......MORE

Many people with HIV not disclosing at GUM clinics: estimates of undiagnosed infections may be too high

Michael Carter | 5 years ago

Many people with HIV are not disclosing their status when using sexual health clinics, according to......MORE

Triple trouble: infection with hepatitis B increases risk of death for people with HIV and hepatitis C co-infection

Michael Carter | 5 years ago

Infection with hepatitis B virus (HBV) is associated with a poorer prognosis for people living with......MORE

Combining tenofovir with FTC or 3TC boosts chances of HBV suppression for people co-infected with HIV

Michael Carter | 5 years ago

A study involving people co-infected with HIV and hepatitis B virus (HBV) shows that antiretroviral......MORE

Frailty increases the risk of fragility fractures in men living with HIV: data collected in routine HIV care can help predict risk

Michael Carter | 5 years ago

Important physiologic markers of frailty are associated with fragility fractures in men living with......MORE

Couples study in Uganda finds no HIV infections from partners on antiretroviral therapy

Gus Cairns | 5 years ago

A longitudinal cohort study of heterosexual couples in Uganda has found more evidence of the effica......MORE

Condoms used in one-in-four heterosexual encounters in the US

Gus Cairns | 5 years ago

A quarter of heterosexual adults in the United States used a condom the last time they had vaginal ......MORE

Tenofovir, atazanavir/ritonavir and Kaletra associated with kidney problems in patients taking HIV therapy

Michael Carter | 5 years ago

Data from a large study into the safety of anti-HIV drugs suggests that the antiretrovirals tenofov......MORE

Media campaign on acute HIV infection symptoms has limited impact

Roger Pebody | 5 years ago

A advertising campaign and website that aimed to raise awareness among gay men in Seattle, Washingt......MORE

More evidence of sexual transmission of hepatitis C among HIV-positive gay men in the US

Michael Carter | 5 years ago

Investigators in the US have found a high incidence of hepatitis C virus (HCV) infection among HIV-......MORE

Circumcision makes no difference to HIV infection in UK gay men

Gus Cairns | 5 years ago

An analysis of an online and gay-venue survey of white, British-born, gay and bisexual men in the U......MORE

Was higher viral load responsible for the African HIV epidemic?

Gus Cairns | 5 years ago

Researchers from Cornell University in New York have found that the average HIV viral load of peopl......MORE

Crystal meth and London gay men – examining the evidence

Roger Pebody | 5 years ago

Last month the respected medical journal The Lancet published a news feature, describing an increas......MORE

Test and treat must go beyond couples to control HIV in Africa

Michael Carter | 5 years ago

A focus on stable couples when attempting to reduce HIV transmission through offering antiretrovira......MORE

Neonatal male circumcision feasible in resource-limited settings; Mogen clamp may have advantages

Michael Carter | 5 years ago

Neonatal male circumcision can be safely performed in resource-limited settings, according to the r......MORE

Pregnancy does not increase risk of nevirapine side-effects

Michael Carter | 5 years ago

Pregnancy does not increase the risk of nevirapine (Viramune) associated side-effects, according to......MORE

AIDS-defining illnesses, especially TB, more frequent at high CD4 counts in Africa and Asia

Carole Leach-Lemens | 5 years ago

Rates of death and illness remained 'substantial' even at higher CD4 cell counts among people recei......MORE

'Intensive' antiretroviral regimen achieves rapid suppression of HIV in semen

Michael Carter | 5 years ago

Adding maraviroc and raltegravir to standard HIV treatment regimens achieves rapid suppression of v......MORE

Results of TB vaccine trial give cause for optimism, say researchers

Michael Carter | 5 years ago

Results of a trial have been praised for “providing hard evidence about protection against tuberc......MORE

HIV incidence in gay men unchanged in England and Wales, despite more testing

Gus Cairns | 5 years ago

A paper in The Lancet by scientists from the UK’s Medical Research Council and the Health Protect......MORE

Tenofovir impairs enzyme that stops cells ageing

Gus Cairns | 5 years ago

A team of Australian researchers has found that tenofovir and, to a lesser extent, other drugs from......MORE

Spanish research shows that liver stiffness can predict outcomes in people co-infected with HIV and hepatitis C

Michael Carter | 5 years ago

Liver stiffness is a strong predictor of hepatic complications and all-cause mortality in people co......MORE

Hospital exposure the source of XDR-TB infections, underlining the need for adequate infection control

Michael Carter | 5 years ago

Numerous hospital transmissions – rather than a single source – fuelled the outbreak of extensi......MORE

Screening can reduce number of patients in need of a doctor's time in busy South African clinic

Carole Leach-Lemens | 5 years ago

Screening patients to identify those who are stable on treatment in a high-volume, large urban publ......MORE

Systematic review confirms that efavirenz is a safer option than nevirapine for adults and children starting HIV therapy

Michael Carter | 5 years ago

Efavirenz is a safer option than nevirapine for adults and children starting antiretroviral therapy......MORE

Support needed to prevent missed clinic visits becoming long-term disengagement from care

Roger Pebody | 5 years ago

Missed clinic visits may be unintentional or intentional, with complex reasons that change over tim......MORE