Featured NHIVNA news
Coronavirus (COVID-19) and HIV - BHIVA Statements
by NHIVNA Admin, 2020-03-25 14:05
NHS England and local authorities must ensure routine availability of PrEP for HIV prevention by 1 April 2019, says coalition of charities
by NHIVNA Admin, 2018-07-17 09:00
HIV Nursing 2017
by NHIVNA Admin, 2017-06-17 10:55
Other latest news
How can researchers reduce risks to sexual partners in studies involving treatment interruptions?Roger Pebody | 5 years ago As studies working towards a functional cure or HIV eradication are creating risks not only fo......MORE |
Deportation fears, uncertainty over health insurance and stigma are barriers to accessing HIV services for undocumented African migrants in the USKrishen Samuel | 5 years ago Qualitative research carried out with undocumented African migrants in New York City revealed ......MORE |
Hepatitis C does not raise risk of heart disease or cancers in people with HIVKeith Alcorn | 5 years ago Hepatitis C coinfection does not increase the risk of cardiovascular disease or non-AIDS cance......MORE |
Less than half of adolescents with HIV since birth in the US have an undetectable viral loadMichael Carter | 5 years ago Engagement with the HIV care continuum among individuals with perinatally-acquired HIV in the ......MORE |
What’s the relationship between PrEP, condom use and STIs?Roger Pebody | 5 years ago HIV experts and professionals agree that pre-exposure prophylaxis (PrEP) is a valuable additio......MORE |
Gay and bisexual men with problematic chemsex are a diverse group with significant sexual and psycho-social risksMichael Carter | 5 years ago Men who have sex with men (MSM) seeking support because of chemsex are a diverse group and hav......MORE |
Australian gay and bisexual men interested in switching to on-demand PrEPUnity Sandasi | 5 years ago Half of gay and bisexual men using PrEP in Australia would be interested in switching from tak......MORE |
Starting ART at a high CD4 cell count has clear benefits for people with a low viral loadMichael Carter | 5 years ago Starting antiretroviral therapy (ART) has significant benefits and entails few risks for indiv......MORE |
Major TB reduction impossible without expansion of ART coverageKeith Alcorn | 5 years ago Tuberculosis incidence in sub-Saharan Africa is falling too slowly to meet global targets of a......MORE |
One in five Americans living with HIV experience severe anxiety on an almost daily basisMichael Carter | 5 years ago A fifth of HIV-positive adults in the United States regularly experience symptoms of anxiety, ......MORE |
Immediate treatment is probably especially beneficial for people with recent HIV infectionKeith Alcorn | 5 years ago Immediate initiation of antiretroviral treatment produced the biggest boost in CD4 cell count ......MORE |
Nine HIV diagnoses in men on PrEP waiting list, ManchesterRoger Pebody | 5 years ago Nine gay men are known to have seroconverted since being put on a waiting list for pre-exposur......MORE |
Older, out-of-school and anonymous partners pose more HIV infection risk for adolescent girls in South AfricaKrishen Samuel | 5 years ago South African research has found that adolescent girls and young women (aged 13-23) were more ......MORE |
Transgender women tell researchers how to increase the uptake of PrEP in their communityRoger Pebody | 5 years ago Transgender women and transfeminine nonbinary individuals suggested a number of key issues tha......MORE |
High awareness but low uptake of PrEP among black and Hispanic transgender women in US studyMichael Carter | 5 years ago There is high awareness but low uptake of HIV PrEP (pre-exposure prophylaxis) among black and ......MORE |
Cases of hair loss among African-American women reported after switch to new tenofovir formulaMichael Carter | 5 years ago Hair loss (alopecia) occurred in six African-American women living with HIV after switching to......MORE |
Antiretrovirals do not cause neurodevelopmental harm to uninfected infantsCarole Leach-Lemens | 5 years ago In the first five years of life the neurological development of HIV-exposed but uninfected inf......MORE |
No HIV infections over two years among MSM and transgender individuals taking event-driven PrEPMichael Carter | 5 years ago No HIV infections occurred over two years of follow-up among individuals taking event-driven p......MORE |
What challenges must Nigeria overcome to eliminate vertical transmission of HIV?Carole Leach-Lemens | 5 years ago Despite impressive health system-related achievements in the prevention of mother-to-child tra......MORE |
Frequent drug-drug interactions in older people with HIV in FranceAlain Volny-Anne | 5 years ago Drug-drug interactions are common in people over the age of 65 living with HIV and this substa......MORE |
PrEP reduces HIV infections by over 95% in US ‘real world’ studyGus Cairns | 5 years ago A study of people prescribed pre-exposure prophylaxis (PrEP) over a four-year period at a larg......MORE |
Study illuminates PrEP treatment pathway and its facilitators and barriers for women in the BronxMichael Carter | 5 years ago Self-perceived HIV risk, learning about pre-exposure prophylaxis (PrEP) via trusted sources, p......MORE |
ART for treatment-experienced people with virological failure can omit NRTIs if three active drugs availableMichael Carter | 5 years ago Treatment for HIV-positive individuals with persistent viral replication despite therapy with ......MORE |
Injectable hormonal contraceptive does not raise HIV risk, large trial findsKeith Alcorn | 5 years ago A large trial has found no difference in the risk of acquiring HIV for women using three diffe......MORE |
In unique case, Australian man appears to have cleared his HIV infectionGus Cairns | 5 years ago Researchers in Sydney, Australia have identified a patient who appears to have spontaneously c......MORE |
US insurers must now cover PrEPRoger Pebody | 5 years ago An influential guidelines body in the United States has put its full weight behind pre-exposur......MORE |
Just 18% of people with hepatitis/HIV co-infection and cirrhosis are screened for liver cancer as often as recommendedRoger Pebody | 5 years ago ...MORE |
Following an HIV treatment interruption, most children recover immunologicallyCarole Leach-Lemens | 5 years ago Just over one in ten (12%) children and adolescents living with HIV in Europe and Thailand tak......MORE |
Most new HIV infections occur in lower prevalence countries not prioritised by PEPFARMichael Carter | 5 years ago The burden of the global HIV epidemic is disproportionately falling on lower-prevalence countr......MORE |
Hepatitis C more stigmatising than HIV: gay men’s attitudes towards hepatitis C reinfectionKrishen Samuel | 5 years ago Qualitative research with HIV-positive gay and bisexual men in Australia who had been cured of......MORE |
HIV criminalisation cases recorded in 72 countries, including 49 in the last four yearsRoger Pebody | 5 years ago HIV criminalisation continues: a global review has found that HIV-related arrests, investigati......MORE |
Significant health gains from faster switching to second-line ART in sub-Saharan AfricaMichael Carter | 5 years ago Switching to second-line antiretroviral therapy (ART) after a single viral load measurement ab......MORE |
Rectal douching by MSM associated with increased odds of infection with HIV and STIsMichael Carter | 5 years ago Rectal douching may put men who have sex with men (MSM) at increased risk of HIV and other sex......MORE |
Malawi: ART alone isn't enough to stop the TB epidemic among people with HIVMichael Carter | 5 years ago Expanded access to antiretroviral therapy (ART) has been accompanied by big falls in incidence......MORE |
What works against self-stigma? First systematic review aims to find outGus Cairns | 5 years ago A systematic review of whether different interventions helped to overcome self-stigma in peopl......MORE |
High prevalence of stockouts of antiretroviral medicines in South AfricaAlain Volny-Anne | 5 years ago One in five public health facilities in South Africa were unable to supply at least one antire......MORE |
The throat is a major source of gonorrhoea infections in MSMMichael Carter | 5 years ago The throat is a major source of gonorrhoea transmission among men who have sex with men (MSM),......MORE |
TB LAM test improves TB diagnosis in people with low CD4 countsKeith Alcorn | 5 years ago Use of the TB LAM test in people with HIV with CD4 counts below 200 boosted the number of peop......MORE |
Being black and gay: how intersectional stigma impacts on the uptake of PrEPKrishen Samuel | 5 years ago Qualitative research published in the July issue of Social Science & Medicine by Dr Kathe......MORE |
Rapid rehousing support for homeless people living with HIV improves housing and HIV outcomesMichael Carter | 5 years ago Homeless people with HIV who are provided with rapid rehousing and intensive, tailored case ma......MORE |
US study suggests that ageing people with HIV may have an increased risk of arthritisMichael Carter | 5 years ago HIV infection and antiretroviral therapy are associated with increased risk of cartilage damag......MORE |
Analytical treatment interruptions: minimising the risks and maximising their scientific valueAlain Volny-Anne | 5 years ago Recommendations for the safe and appropriate use of ‘analytical treatment interruptions’ h......MORE |
Rate of undiagnosed HIV remains high among black African heterosexuals in LondonMichael Carter | 5 years ago The rate of undiagnosed HIV infection among heterosexual black Africans living in London remai......MORE |
Point-of-care technology for early infant HIV diagnosis speeds up return of HIV test resultsCarole Leach-Lemens | 5 years ago Point-of-care testing for early infant HIV diagnosis is highly effective in reducing turnaroun......MORE |
Rapid adoption of generic HIV drugs could save NHS £7 billion by 2033Keith Alcorn | 5 years ago Prescription of generic versions of antiretroviral drugs for treatment and pre-exposure prophy......MORE |
Decline in chemsex over time in three English clinicsRoger Pebody | 5 years ago In the first study to track chemsex over time, the number of men having chemsex fell by two-th......MORE |
Travel-related health problems common among HIV-positive migrants in France who visit sub-Saharan AfricaMichael Carter | 5 years ago Travel-related illnesses – especially diarrhoea, respiratory complaints and malaria – are ......MORE |
Disclosure of HIV linked to longer relationships for African migrants living in FranceKrishen Samuel | 5 years ago Disclosure of HIV status did not precipitate relationship break-ups after an HIV diagnosis for......MORE |
How does condom use change over time as young MSM get older?Krishen Samuel | 5 years ago A longitudinal study using multiple cohorts of young men who have sex with men in Chicago aime......MORE |
Why has the uptake of lopinavir/ritonavir oral pellets for children been slow?Carole Leach-Lemens | 5 years ago Lopinavir/ritonavir (LPV/r) oral pellets and oral granules for infants and young children livi......MORE |
Opposites Attract study: HIV-positive/negative couples used multiple strategies to prevent HIV transmissionGus Cairns | 5 years ago Two years ago, the Opposites Attract study found no transmissions between 343 regular gay coup......MORE |
Anal cancer treatment less effective and more likely to cause side-effects in people with HIVMichael Carter | 5 years ago Localised chemo-radiation therapy for anal cancer has poorer outcomes and is more likely to ca......MORE |
Most UK clinic staff now tell people about U=U, but not always in the same wayGus Cairns | 5 years ago Two presentations at this month’s British HIV Association (BHIVA) conference in Bournemouth ......MORE |
Breastfeeding with an undetectable viral load: some insights into the current UK situationMichael Carter | 5 years ago Over a third of HIV-positive women in the final stages of pregnancy or who have recently given......MORE |
No reduction in HIV stigma in San Francisco, 2011 to 2017Roger Pebody | 5 years ago In 2013, San Francisco adopted a ‘Getting to Zero’ HIV strategy, with the aim of getting t......MORE |
Fatty liver disease a rising cause of liver problems in people with HIVLiz Highleyman | 5 years ago Now that hepatitis C can be successfully treated, non-alcoholic fatty liver disease (NAFLD) is......MORE |
First data on trans people accessing HIV care in EnglandRoger Pebody | 5 years ago There is a dearth of data on transgender and non-binary people receiving HIV care in the UK, b......MORE |
Naltrexone implants provide better HIV treatment outcomes for those with HIV and opioid addiction in RussiaKrishen Samuel | 5 years ago A double-blind, placebo-controlled randomised trial conducted in Russia found that slow-releas......MORE |
Young people born with HIV more likely to have “mild” verbal memory test deficits if they have ever had an AIDS-defining conditionGus Cairns | 5 years ago A study presented at this year’s Conference on Retroviruses and Opportunistic Infections (C......MORE |
Older black HIV-positive women have more mental distress than other women with HIV, but get less help for itGus Cairns | 5 years ago A study looking at women aged over 45 living with HIV in the UK has found that while black Afr......MORE |
Hepatitis C drugs for all genotypes curing almost everyone who completes treatment, real-world studies showKeith Alcorn | 5 years ago Once-daily combination pills that can treat all genotypes of hepatitis C infection are curing ......MORE |
PrEP should be offered urgently to gay men with a recent STI or multiple condomless partnersRoger Pebody | 5 years ago Analysis of men who acquired HIV in the deferred arm of the PROUD study highlights two risk fa......MORE |
Monoclonal antibody may lead to long-term viral load reductionLiz Highleyman | 5 years ago An experimental monoclonal antibody called PGT121 led to viral suppression that lasted for up ......MORE |
US regulators approve new two-drug combination pill for HIVLiz Highleyman | 5 years ago The US Food and Drug Administration (FDA) this week approved Dovato, a new single-tablet antir......MORE |
HPV vaccination for gay men effectively delivered in sexual health and HIV clinicsMichael Carter | 5 years ago A human papillomavirus (HPV) vaccination programme targeted at men who have sex with men (MSM)......MORE |
Racism, marginalisation and PrEP stereotypes affect PrEP uptake for black MSM in LondonKrishen Samuel | 5 years ago Black men who have sex with men (MSM) in London experience a unique set of motivations and bar......MORE |
English clinic survey finds that 40% of gay men with new hepatitis C infections are HIV negativeGus Cairns | 5 years ago A study of gay and bisexual men diagnosed with recently acquired hepatitis C infection and tre......MORE |
Raltegravir plus lamivudine is likely to work as PrEPGus Cairns | 5 years ago A combination of the drugs raltegravir and lamivudine produced acceptable drug levels in both ......MORE |
Clusters of co-morbidities in people living with HIV show major non-HIV medical needsKeith Alcorn | 5 years ago Most health problems in people living with HIV in two large cohorts can be classified in six ......MORE |
Systematic analysis suggests that circumcision helps protect MSM from infection with HIVMichael Carter | 5 years ago Circumcision protects men who have sex with men (MSM) from infection with HIV, according to a ......MORE |
First year of PrEP in Scotland: more users than expected, few dropouts, few HIV infectionsGus Cairns | 5 years ago The recent report on the first year of the implementation of pre-exposure prophylaxis (PrEP)......MORE |
Viral suppression maintained with alternate-day dosing of efavirenz/tenofovir/emtricitabineKrishen Samuel | 5 years ago No significant differences in viral suppression between groups on daily dosing versus alternat......MORE |
Epidemic of sexually transmitted hepatitis C in gay men now involves both HIV-positive and HIV-negative menMichael Carter | 5 years ago Incidence of acute hepatitis C virus (HCV) among men who have sex with men (MSM) who use pre-e......MORE |
EACS Standard of Care meeting report - Tackling HIV and co-infections in Europe: towards common standardsGus Cairns | 5 years ago This is the full report from the EACS Standard of Care Meeting. It can also be read in three s......MORE |
Opioid overdose deaths are rising among people with HIV in the United StatesLiz Highleyman | 5 years ago A growing number of people with HIV in the US are dying from opioid overdoses, according to a ......MORE |
Non-adherence to HIV treatment for cost-saving reasons reported by 8% in American studyRoger Pebody | 5 years ago Much of the excessive cost of prescription drugs in the United States falls on patients, and n......MORE |
Diet and exercise advice lowers diabetes risk in people with HIVRoger Pebody | 5 years ago Rates of diabetes are higher in people living with HIV than in the general population, but ind......MORE |
Partners of transgender women form a separate HIV risk group, Peruvian study findsGus Cairns | 5 years ago A study from Peru’s capital, Lima, has found that the sexual partners of transgender women t......MORE |
The impact of older antiretrovirals on fat redistribution and cardiovascular risk factors may be irreversibleAlain Volny-Anne | 5 years ago Fat redistribution in people with HIV who have ever taken thymidine analogues and/or didanosin......MORE |
Urine test can provide accurate point-of-care results about PrEP adhereceMichael Carter | 5 years ago A point-of-care urine test can accurately determine if a person is adherent to tenofovir-based......MORE |
Healthcare providers should discuss U=U with all their HIV-positive patientsMichael Carter | 5 years ago Healthcare providers should inform all patients with HIV they cannot transmit HIV to a sexual ......MORE |
Dolutegravir-based second-line ART achieves excellent virological outcomes even in the presence of resistance to recycled NRTIsMichael Carter | 5 years ago Virological response rates were excellent among patients receiving second-line antiretroviral ......MORE |
Higher HIV viral load and lower CD4 count linked to liver cancer riskLiz Highleyman | 5 years ago People living with HIV who have a longer duration of detectable viral load and those with low ......MORE |
TAF: Quick-dissolve combination PrEP insert is effective against HIV infections in monkeys; intermittent solo pill less soGus Cairns | 5 years ago Two studies in monkeys of experimental pre-exposure prophylaxis (PrEP) regimens featuring the ......MORE |
Co-administration of dolutegravir-based treatment and short course of rifapentine/isoniazid (3HP) well tolerated in people living with HIVCarole Leach-Lemens | 5 years ago Co-administration of dolutegravir-based antiretroviral therapy and short course (12 weeks) of ......MORE |
Sixfold increased risk of infant HIV infection and high rates of low birth weight among women with HIV/hepatitis B co-infectionCarole Leach-Lemens | 5 years ago Women with high levels of hepatitis B viraemia (>106IU/ml) who have co-infection with HIV h......MORE |
Thailand’s achievements in HIV are not all widely implementedRoger Pebody | 5 years ago “Thailand is progressing in the right direction to end AIDS, but needs sustained political a......MORE |
‘Gentler cure’ technique produces delay in viral rebound in some people taken off HIV therapyGus Cairns | 5 years ago Researchers have introduced genetic changes into human T-cells that make them virtually immune......MORE |
U=U is a human rights issueKrishen Samuel | 5 years ago Undetectable = Untransmittable (U=U) is a human rights issue, Dr Carrie Foote told the Confere......MORE |
People with HIV may benefit from earlier lung cancer screeningLiz Highleyman | 5 years ago People living with HIV, especially women, may develop lung cancer at an earlier age and with a......MORE |
Self-testing helps the partners of people with HIV to test, but not to link to careRoger Pebody | 5 years ago Asking people living with HIV in Malawi to pass on HIV self-testing kits to their sexual partn......MORE |
HIV capsid inhibitor may offer long-term viral suppressionLiz Highleyman | 5 years ago An experimental HIV capsid inhibitor appears safe and may be able to be administered once ever......MORE |
One in six South Africans drug resistant before starting HIV treatmentKeith Alcorn | 5 years ago One in six people not on treatment in a large South African household survey already had drug-......MORE |
EACS takes steps towards a common, auditable European standard of careGus Cairns | 5 years ago The purpose of the European AIDS Clinical Society's (EACS) meeting last month in Bucharest, R......MORE |
People stay on PrEP for 14 months on average in the US, study findsGus Cairns | 5 years ago Whether HIV pre-exposure prophylaxis (PrEP) is effective depends on whether people take it app......MORE |
Long-acting injectable treatment maintains viral suppressionLiz Highleyman | 5 years ago A combination of two long-acting injectable anti-HIV drugs taken once monthly had a very low r......MORE |
Are CD4 counts still useful in the 'treat all' era?Keith Alcorn | 5 years ago CD4 cell testing before starting treatment is still essential even in the era of 'treat all' g......MORE |
Multiple benefits to scaling up universal test and treat in AfricaRoger Pebody | 5 years ago As well as the important findings of PopART, the largest HIV prevention trial ever conducted, ......MORE |
‘Molecular scissors’ successfully remove HIV genes from all tissues in infected monkeysGus Cairns | 5 years ago The top story from the Conference on Retroviruses and Opportunistic Infections (CROI 2019) in ......MORE |
Neural tube defects and integrase inhibitors: still waiting for stronger evidenceKeith Alcorn | 5 years ago Researchers are still unable to determine if exposure to integrase inhibitors around conceptio......MORE |
Integrase inhibitor treatment leads to greater weight gainKeith Alcorn | 5 years ago More evidence that HIV integrase inhibitor treatment is associated with weight gain, and that ......MORE |
Hepatitis C drops among HIV-positive London gay men after direct-acting antiviral scale-upLiz Highleyman | 5 years ago New cases of hepatitis C virus (HCV) infection among HIV-positive gay and bisexual men seen at......MORE |
How many people who have used PrEP get HIV the same year? New York study finds outGus Cairns | 5 years ago ...MORE |
Chronic obstructive pulmonary disease (COPD) increases the risk of heart attack in people with HIVKeith Alcorn | 5 years ago Chronic obstructive pulmonary disease (COPD) increases the risk of heart attack in people wit......MORE |
The length of time Americans with HIV remain infectious is falling, but slowlyRoger Pebody | 5 years ago In 2016, more than half of people with HIV in the United States took more than three years to ......MORE |
Integrase inhibitors give greater chance of viral suppression at delivery in pregnant womenKeith Alcorn | 5 years ago Integrase inhibitor-based treatment with either raltegravir (Isentress) or dolutegravir (Tivic......MORE |
Women with HIV may have higher breast cancer mortalityLiz Highleyman | 5 years ago HIV-positive women with breast cancer appear to have decreased survival compared with HIV-nega......MORE |
HIV infections lowered by 30% in universal testing and treatment studyRoger Pebody | 5 years ago Communities in southern Africa which received a door-to-door HIV testing intervention and supp......MORE |
Descovy is non-inferior to Truvada for daily PrEPRoger Pebody | 5 years ago A daily pill containing the newer formulation of tenofovir in combination with emtricitabine (......MORE |
Sudden cardiac death is more common in people with HIVKeith Alcorn | 5 years ago Deaths caused by sudden cardiac arrest are significantly more common in people living with HIV......MORE |
London patient in long-term HIV remission after stem cell transplantLiz Highleyman | 5 years ago A London man has no remaining detectable HIV a year and a half after undergoing a bone marrow ......MORE |
Point-of-care viral load testing improves treatment outcomes and retention in careRoger Pebody | 5 years ago Same-day provision of results from a point-of-care viral load test – rather than waiting wee......MORE |
55% drop in HIV incidence in gay men in England in just two yearsRoger Pebody | 5 years ago In just two years, the incidence of new HIV infections in men who have sex with men attending ......MORE |
HIV-positive participant in vaccine study passes virus to sexual partner during treatment interruptionRoger Pebody | 5 years ago An HIV-positive man transmitted HIV to his sexual partner after interrupting antiretroviral th......MORE |
Specialist memory clinic in Brighton shows that HIV-associated cognitive disorder is being over-diagnosedMichael Carter | 5 years ago Cognitive impairment in people with HIV has multiple causes and HIV-associated neurocognitive ......MORE |
Mismatch between US infant feeding policies and the lived experience of HIV-positive womenKrishen Samuel | 5 years ago US guidelines recommending that HIV-positive women feed their infants formula milk instead of ......MORE |
Cocaine use associated with poor adherence to PrEP and dropping out of careMichael Carter | 5 years ago Cocaine users have poorer adherence to HIV pre-exposure prophylaxis (PrEP) and engagement with......MORE |
In the USA, only two in five PrEP users keep taking it over two yearsRoger Pebody | 5 years ago Real-world data from a large American chain of retail pharmacies show that only two in five pe......MORE |
Shifting social norms around what “safer” sex is: perspectives of HIV-negative men in CanadaKrishen Samuel | 5 years ago HIV-negative men who have sex with men (MSM) living in Vancouver, Canada are redefining ways t......MORE |
Gay men in New York rate an undetectable viral load as less effective than PrEPRoger Pebody | 5 years ago Gay, bisexual and other men who have sex with men in New York City rate daily pre-exposure pro......MORE |
Nicotine metabolised at a faster rate among HIV-positive smokers - implications for quitting smokingMichael Carter | 5 years ago HIV-positive smokers metabolise nicotine at a significantly higher rate than HIV-negative indi......MORE |
Smoking cannabis is an independent risk factor for lung disease in people with HIVMichael Carter | 5 years ago Frequent cannabis smoking is a risk factor for lung disease in HIV-positive men, according to ......MORE |
HIV prevention cascades could highlight gaps in prevention programmesRoger Pebody | 5 years ago A simple HIV prevention cascade could be a powerful tool for advocates, policy makers and fund......MORE |
DAA treatment reduces the risk of death and liver cancer in people with hepatitis CKeith Alcorn | 5 years ago Treatment with direct-acting antivirals (DAAs) reduced the risk of death, liver cancer and dea......MORE |
First evidence of HIV reservoirs in macrophagesAlain Volny-Anne | 5 years ago Basic scientists in France have recently discovered that macrophages located in urethral tissu......MORE |
Smoking, cholesterol, blood pressure are more important causes of disease than HIV in people living with HIVKeith Alcorn | 5 years ago Preventing smoking, lowering cholesterol, controlling blood pressure and curing hepatitis C wo......MORE |
Tackling HIV and hepatitis C in Europe: towards minimum standardsGus Cairns | 5 years ago Despite the huge disparities in care that were highlighted, last week's Standard of Care for ......MORE |
Glimmers of hope: moving towards better HIV and TB treatment in eastern EuropeGus Cairns | 5 years ago Eastern Europe continues to have one of the worst HIV epidemics in the world outside sub-Sahar......MORE |
Navigating rules and reality: HIV disclosure, infectiousness and legal obligations in SwedenKrishen Samuel | 5 years ago Despite generally positive relationships with HIV clinic staff, men living with HIV in Sweden ......MORE |
HIV non-disclosure laws perpetuate social injustices against women in CanadaKrishen Samuel | 5 years ago People living with HIV in Canada can be charged with aggravated sexual assault and be register......MORE |
HIV infection an independent risk factor for poorer survival from liver cancerMichael Carter | 5 years ago Infection with HIV is associated with significantly worse survival for people with hepatocellu......MORE |
Two new types of cell therapy could target reservoir cells and permanently stop HIV infectionGus Cairns | 5 years ago Two studies published last month described promising new approaches which could stop HIV infec......MORE |
Is ageing in people living with HIV accelerated or accentuated?Alain Volny-Anne | 5 years ago Earlier than normal ageing in people living with HIV has been debated for many years. The issu......MORE |
Non-alcoholic fatty liver disease: a growing health problem in people with HIVKeith Alcorn | 5 years ago Non-alcoholic fatty liver disease (NAFLD) is a major emerging health challenge for people liv......MORE |
HIV-positive women less likely to be treated successfully for cervical pre-cancerLiz Highleyman | 5 years ago Women living with HIV are more likely than HIV-negative women to have residual or recurring ab......MORE |
PrEP promotion should be positive and inclusiveRoger Pebody | 5 years ago Pre-exposure prophylaxis (PrEP) programmes should adopt modern marketing strategies that are a......MORE |
How did Kenya build Africa’s largest PrEP programme?Roger Pebody | 5 years ago Around 25,000 people are taking pre-exposure prophylaxis (PrEP) in Kenya, making it Africa’s......MORE |
Barriers to HCV treatment access from the drug user's point of view: stigma, complex lives and damaged veinsKeith Alcorn | 5 years ago Despite access to hepatitis C treatment, many people who inject drugs still perceive numerous ......MORE |
Social and network factors may explain higher HIV infection rates for black men who have sex with men in the USKrishen Samuel | 5 years ago Young black gay and bisexual men are more likely to be exposed to HIV than their white or Hisp......MORE |
Multi-drug resistant Shigella detected in the UK and USA, mostly in gay menMichael Carter | 5 years ago Public health authorities in the UK have issued a warning about a highly drug-resistant strain......MORE |
Atripla or efavirenz plus Truvada failed one in 16 people in first yearGus Cairns | 5 years ago Estimates of how often people on antiretroviral therapy (ART) do not remain virally undetectab......MORE |
Efavirenz in pregnancy is at least as safe as other antiretroviralsRoger Pebody | 5 years ago An individual patient data analysis of almost 25,000 pregnancies in women living with HIV has ......MORE |
Half of Malaysian doctors admit to some discrimination against patients with HIVRoger Pebody | 5 years ago Just over half of physicians at two of Malaysia’s leading medical universities expressed som......MORE |
HIV and schistosomiasis programmes should be combined to reduce the spread of HIVMichael Carter | 5 years ago Testing and treatment programmes for HIV and schistosomiasis (also known as snail fever or bil......MORE |
Co-infection with HIV and HCV does not increase the risk of end-stage liver disease or liver cancerKeith Alcorn | 5 years ago People with HIV and hepatitis C are no longer at higher risk of end-stage liver disease than p......MORE |
Meta-analysis finds high but variable STI rates in PrEP studies - is PrEP the cause or a potential solution?Gus Cairns | 5 years ago A new meta-analysis of 20 studies and roll-out projects of HIV pre-exposure prophylaxis (PrEP)......MORE |
Do integrase inhibitors raise the risk of obesity?Keith Alcorn | 5 years ago People who take an integrase inhibitor as part of their HIV treatment appear to gain more weig......MORE |
Potential drug interactions among people with HIV taking statinsMichael Carter | 5 years ago Drug interactions remain a potential problem for HIV-positive people who are treated with stat......MORE |
Growth in positive attitudes towards PrEP among Australian gay and bisexual menMichael Carter | 5 years ago Willingness to consider using pre-exposure prophylaxis (PrEP) increased between 2011 and 2017 ......MORE |
Six innovative models for PrEP servicesRoger Pebody | 5 years ago For pre-exposure prophylaxis (PrEP) to have a substantial public health impact, access to PrEP......MORE |
South Africa reports successful third-line HIV treatment programmeEsther Nakkazi | 5 years ago People with resistance to first- and second-line antiretroviral drugs can still achieve high r......MORE |
Improved liver function, but progressive kidney damage, among children on antiretroviral therapy in EthiopiaCarole Leach-Lemens | 5 years ago Among HIV-positive children with liver and kidney abnormalities, liver enzyme abnormalities im......MORE |
Scientists achieve the first proof of concept for an HIV broadly neutralising antibody vaccine in monkeysGus Cairns | 5 years ago In a step forward in the search for an HIV vaccine, Professor Denis Burton and colleagues from......MORE |
Links between stigma, suicidal thoughts and less HIV testing in Nigerian men who have sex with menKrishen Samuel | 5 years ago Contemplating suicide – an indication of poor mental health and a risk factor for committing......MORE |
Italian study shows growth in heart and kidney problems in people living with HIVKeith Alcorn | 5 years ago Reduced kidney function, high blood pressure and cardiovascular disease have each become more......MORE |
HIV treatment outcomes continue to get better, says large analysisMichael Carter | 5 years ago The efficacy of first-line antiretroviral therapy (ART) continues to improve, according to an ......MORE |
HIV infections among black gay men taking PrEP, probably due to poor adherenceMichael Carter | 5 years ago ...MORE |
UNAIDS 90-90-90 target is reachable for most sub-Saharan Africa countriesEsther Nakkazi | 5 years ago A mathematical model has shown that just under half of countries in sub-Saharan Africa are lik......MORE |
Public Health England warns that improved treatment and testing rates for STIs in the UK could be imperilled by cutsGus Cairns | 5 years ago A review of one hundred years of diagnoses of sexually transmitted infections (STIs) in the UK......MORE |
Benefits of dolutegravir treatment for all substantially outweigh the risksKeith Alcorn | 5 years ago Providing an antiretroviral regimen of dolutegravir, tenofovir and lamivudine to all adults li......MORE |
Managing sexual and survival risks: the impact of inequity and stigma on Jamaican MSM and trans womenKrishen Samuel | 5 years ago Two recent qualitative studies highlight Jamaican men who have sex with men (MSM) and transgen......MORE |
Women with HIV have increased risk of missed menstrual periodsMichael Carter | 5 years ago Women living with HIV have a significantly higher risk of the menstrual disorder amenorrhea (m......MORE |
Stigma, access and testing: why HIV is still rising in EuropeGus Cairns | 5 years ago The latest annual surveillance report by the European Centre for Disease Prevention and Contro......MORE |
Ten reasons people stop attending HIV care in ZambiaRoger Pebody | 5 years ago Patient-provider relationships are strained by poor working conditions and rigid application o......MORE |
Doubt cast on link between tenofovir disoproxil and bone fracturesMichael Carter | 5 years ago Treatment with tenofovir disoproxil fumarate (TDF) does not increase the risk of fractures, ac......MORE |
How dangerous is gonorrhoea resistance and can it be halted?Gus Cairns | 5 years ago The bacterium that causes the common sexually transmitted infection (STI) gonorrhoea develops ......MORE |
New BHIVA guidelines on HIV care in pregnancy and after birthKeith Alcorn | 5 years ago New British HIV Association (BHIVA) guidelines on the management of HIV in pregnancy have been......MORE |
Digital health services highly effective in early infant diagnosis of HIV in KenyaCarole Leach-Lemens | 5 years ago A digital health system combining online services with text messages is highly effective in ea......MORE |
CD4 count recovery: French study reaffirms why it is important to test and treat HIV earlyAlain Volny-Anne | 5 years ago Seven-in-ten people with HIV taking combined antiretroviral therapy for the first time recover......MORE |
High prevalence of diabetes and pre-diabetes in people at London HIV clinicsKeith Alcorn | 5 years ago Around a third of people living with HIV receiving care at three large HIV clinics in south Lo......MORE |
HIV diagnoses fell in the UK in 2017 for the first time among all risk groups, all ethnicities and in all regions, annual report revealsGus Cairns | 5 years ago The 2018 report from Public Health England is entitled Progress towards ending the HIV epidem......MORE |
Australian experience shows high DAA uptake and rapid fall in rates of HCV viraemia among people who inject drugsMichael Carter | 5 years ago Providing hepatitis C virus (HCV) therapy with direct-acting antivirals (DAAs) to people who i......MORE |
All people with HIV-2 should receive HIV treatment - without it, most will progress to AIDS and deathMichael Carter | 5 years ago Most people with HIV-2 infection will progress to AIDS and death unless they receive antiretro......MORE |
High levels of unmet PrEP needs among transgender women in BrazilKrishen Samuel | 5 years ago A study recently published in The Journal of Acquired Immune Deficiency Syndromes indicates th......MORE |
‘Negligible’ risk of HIV transmission with a suppressed viral load, Canadian public health officials tell prosecutorsRoger Pebody | 5 years ago The potential for sexual HIV transmission when a person living with HIV adheres to antiretrovi......MORE |
Viral suppression key to preventing mother-to-child transmission, but food insecurity, TB and STIs may also be risk factorsMichael Carter | 5 years ago Reducing maternal viral load during pregnancy is the most important factor in preventing mothe......MORE |
Two cases of HIV transmission through breastfeeding in mothers with undetectable viral load reportedKeith Alcorn | 5 years ago Two cases of HIV transmission from mother to infant during the breastfeeding period when mothe......MORE |
'Alarmingly high' HIV incidence among MSM and transgender women in sub-Saharan AfricaMichael Carter | 5 years ago HIV incidence among men who have sex with men (MSM) and transgender women in sub-Saharan Afric......MORE |
Removable PrEP implant produces high drug levels in rabbits; further studies plannedGus Cairns | 5 years ago A small removable plastic implant resembling a tiny piece of dry spaghetti is capable of deliv......MORE |
Viral load in semen rapidly rebounds to infectious levels during HIV treatment breaksMichael Carter | 5 years ago Viral load rebounds rapidly in semen to potentially infectious levels following interruption o......MORE |
PROUD qualitative findings: PrEP’s impact on sexual behaviourKrishen Samuel | 5 years ago Qualitative data from the PROUD study revealed that pre-exposure prophylaxis (PrEP) is an impo......MORE |
Hepatitis C is detectable in rectal and nasal fluidKeith Alcorn | 5 years ago High levels of hepatitis C virus (HCV) can be found in the rectal and nasal fluids of people w......MORE |
High prevalence and incidence of hypertension among South Africans starting ARTMichael Carter | 5 years ago There is a high prevalence and incidence of hypertension (raised blood pressure) among HIV-pos......MORE |
Recent incarceration increases HIV and hepatitis C risk for people who inject drugsMichael Carter | 5 years ago People who inject drugs (PWID) recently released from prison or jail have a substantially incr......MORE |
Transgender women taking PrEP have lower levels of PrEP drugs, especially in rectal tissues, than cisgender menGus Cairns | 5 years ago A study presented at last month’s HIV Research for Prevention conference (HIVR4P) in Madrid ......MORE |
Early HIV treatment reduces the risk of liver fibrosisMichael Carter | 5 years ago Early antiretroviral therapy (ART) reduces the risk of liver fibrosis progression in people li......MORE |
How has Glasgow responded to an outbreak of HIV among people who inject drugs?Keith Alcorn | 6 years ago Intensive efforts to reach people who inject drugs who have acquired HIV in a recent transmiss......MORE |
Fostemsavir, novel gp120 inhibitor, salvages nearly half of people with no other treatment options leftGus Cairns | 6 years ago The recent International Congress on Drug Therapy in HIV Infection (HIV Glasgow) featured tria......MORE |
PrEP sorting: HIV-negative gay men prefer sexual partners who are using PrEPKrishen Samuel | 6 years ago PrEP status is a significant factor for HIV-negative men who have sex with men (MSM) when sele......MORE |
Dolutegravir plus darunavir maintains viral suppression without NRTIsLiz Highleyman | 6 years ago A dual antiretroviral regimen containing dolutegravir (Tivicay) and boosted darunavir (Prezist......MORE |
Gammora does not cure HIVRoger Pebody | 6 years ago An Israeli biotech company has issued a misleading press release which has encouraged some med......MORE |
Reaching the men: who are the partners of the young women with HIV in South Africa?Gus Cairns | 6 years ago ...MORE |
Prolonged HIV suppression is possible using ibalizumab, analysis of highly drug-resistant people showsKeith Alcorn | 6 years ago A treatment regimen containing ibalizumab (Trogarzo), a monoclonal antibody designed to block ......MORE |
How safe is PrEP? Meta-analysis finds no increased risk of serious side-effectsGus Cairns | 6 years ago A meta-analysis of randomised controlled trials of tenofovir or tenofovir/emtricitabine as pre......MORE |
Hepatitis C increases the risk of premature delivery for pregnant women with HIVKeith Alcorn | 6 years ago Co-infection with hepatitis C greatly increases the risk of pre-term delivery for pregnant wom......MORE |
Dolutegravir or lower-dose efavirenz equally effective, but less resistance with dolutegravirKeith Alcorn | 6 years ago Dolutegravir-based treatment was no more effective than treatment based on a 400mg dose of efa......MORE |
Going local - prevention conference hears about rings, douches, and soluble suppositoriesGus Cairns | 6 years ago ...MORE |
Beyond Truvada - what is the future of PrEP?Roger Pebody | 6 years ago ...MORE |
Bictegravir matches dolutegravir in first-line treatmentKeith Alcorn | 6 years ago A triple combination containing the new integrase inhibitor bictegravir proved just as effecti......MORE |
Neural tube defects and integrase inhibitors: studies show no further evidence of increased riskKeith Alcorn | 6 years ago No further evidence of an increased risk of infant neural tube defects related to the use of d......MORE |
Two-drug protease inhibitor treatment as effective as three-drug treatment - and fewer stop due to side-effectsKeith Alcorn | 6 years ago Antiretroviral treatment with a boosted protease inhibitor and one other drug is just as effec......MORE |
Boston HIV clinic sees 90% reduction in infections in people being prescribed PrEPGus Cairns | 6 years ago The Fenway clinic in Boston, Massachusetts, one of the first to institute a large pre-exposure......MORE |
Substantial gaps in PrEP care continuum for trans women in San FranciscoRoger Pebody | 6 years ago Only a third of trans women in San Francisco have talked to a healthcare provider about pre-ex......MORE |
PrEP providers and communicators should stop talking about ‘risk’Roger Pebody | 6 years ago It’s unhelpful to frame the use of pre-exposure prophylaxis (PrEP) in terms of ‘risky beha......MORE |
First large HIV prevention trial using antibodies will probably not be the lastGus Cairns | 6 years ago The HIV Research for Prevention conference (HIVR4P 2018) in Madrid last week was dominated by ......MORE |
Generic PrEP bought online has correct amounts of emtricitabine and tenofovirMichael Carter | 6 years ago People buying generic PrEP (pre-exposure prophylaxis) online can be confident they are buying ......MORE |
Vaginal rings, films, inserts or gels - it’s all about choiceRoger Pebody | 6 years ago There is no single HIV prevention technology which suits everyone – young African women who ......MORE |
The Miami monkey cured with two antibodiesGus Cairns | 6 years ago A ‘functional cure’ of HIV has been achieved in one monkey given gene therapy that induced......MORE |
The long tail of injectable PrEP is especially long for womenRoger Pebody | 6 years ago Around four in ten women and one in ten men taking injectable cabotegravir as pre-exposure pro......MORE |
Far more people may be using PrEP than we know, HIV prevention conference hearsGus Cairns | 6 years ago Many more gay men and men who have sex with men (MSM) may be using pre-exposure prophylaxis (P......MORE |
People with HIV can safely use immunotherapy for cancerLiz Highleyman | 6 years ago Treatment with an immune checkpoint inhibitor appears to be well tolerated and may work as wel......MORE |
Viral suppression within three months of HIV diagnosis should be a policy target, NYC officials sayMichael Carter | 6 years ago An undetectable viral load within three months of HIV diagnosis should be added as a target to......MORE |
380,000 people on PrEP globally, mostly in the USA and Africa [updated]Roger Pebody | 6 years ago At least 381,580 people have started to take pre-exposure prophylaxis (PrEP) in 68 countries,......MORE |
Drug resistance accumulates fast in people with low but detectable viral loads, Kenyan study findsGus Cairns | 6 years ago A study measuring HIV drug resistance at two timepoints in Kenyan patients on second-line, pro......MORE |
First HIV-positive to HIV-negative liver transplant raises intriguing questions for cure researchKeith Alcorn | 6 years ago An HIV-negative child received a liver transplant from its HIV-positive mother and now appears......MORE |
Majority of US young adults who use drugs are not tested for hepatitis C or HIVLiz Highleyman | 6 years ago Only about a third of adolescents and young adults diagnosed with opioid use disorder in the U......MORE |
Integrated support intervention improves engagement with HIV and methadone treatment among people who inject drugsMichael Carter | 6 years ago Providing information on how to navigate care pathways, psychosocial support, and immediate an......MORE |
Studies confirm long-term effectiveness of new single-tablet regimensLiz Highleyman | 6 years ago The newest once-daily, all-in-one HIV combination pills can maintain undetectable viral load f......MORE |
Pain highly prevalent among people with HIV and has a major impact on mental health, quality of life, employment and use of healthcareMichael Carter | 6 years ago Pain is very common among people living with HIV (PLWH) and has a major impact on quality of l......MORE |
Combined treatment for smoking cessation, anxiety and depression more effective than smoking cessation aloneKrishen Samuel | 6 years ago A randomised control trial published in The Journal of Acquired Immune Deficiency Syndromes by......MORE |
Internet-based intervention effective in the treatment of depression in people living with HIVAlain Volny-Anne | 6 years ago An online self-help intervention is effective in the treatment of mild to moderate depressive ......MORE |
Wide range of views about switching to weekly, monthly or biannual ARTMichael Carter | 6 years ago Two-thirds of people taking combination antiretroviral therapy (cART) would be interested in s......MORE |
Anal HPV-16 infection significantly more common in men who have sex with men, especially those living with HIVKeith Alcorn | 6 years ago Anal infection with HPV-16, the type of human papillomavirus most strongly associated with ana......MORE |
Older people less likely to be offered an HIV test in English sexual health clinicsRoger Pebody | 6 years ago Despite their mandate to offer HIV testing to all attendees, sexual health clinics in England ......MORE |
Efavirenz, but not dolutegravir, linked to neurological problems in childrenLiz Highleyman | 6 years ago Children born to HIV-positive women who take efavirenz (Sustiva or Stocrin, also a component o......MORE |
TB vaccine halves risk of disease in people with latent TBKeith Alcorn | 6 years ago A vaccine against tuberculosis (TB) reduced the risk of developing active TB in HIV-negative p......MORE |
Hepatitis C elimination in people living with HIV in the UK is feasible by 2021, British HIV Association saysKeith Alcorn | 6 years ago Hepatitis C co-infection can be eliminated in people living with HIV in the United Kingdom by ......MORE |
Another rare PrEP failure reported in San FranciscoLiz Highleyman | 6 years ago A San Francisco man was apparently infected with partially resistant HIV despite consistent us......MORE |
Dual-antibody combination therapy produces three to seven months of viral suppression without pillsGus Cairns | 6 years ago A group of researchers have for the first time used infusions of antibodies to produce prolong......MORE |
Doravirine combination works well as a switch optionLiz Highleyman | 6 years ago A combination pill containing doravirine (Delstrigo) maintains undetectable viral load in peop......MORE |
Some gay and bisexual men see PrEP as a 'social problem'Michael Carter | 6 years ago Gay and bisexual men have differing attitudes towards men who are using pre-exposure prophylax......MORE |
Adolescent girls’ male partners are not all much older, much wealthier ‘sugar daddies’Roger Pebody | 6 years ago The male partners of adolescent girls and young women in eSwatini (Swaziland) and South Africa......MORE |
People living with HIV underestimate the harm of smokingKeith Alcorn | 6 years ago People with HIV in Denmark who smoke greatly underestimate the impact of smoking on life expec......MORE |
Most PrEP users in Berlin obtained it from informal channelsKrishen Samuel | 6 years ago Over half of men who have sex with men (MSM) living in Berlin who were using HIV pre-exposure ......MORE |
Large proportion of people living with HIV, including gay men, would like to have childrenMichael Carter | 6 years ago Approximately 40% of HIV-positive adults starting antiretroviral therapy (ART) in the United S......MORE |
One in five exposed to TB during HIV clinic visits, Malawi study findsKeith Alcorn | 6 years ago As many as one in five people attending an HIV clinic in Malawi had prolonged exposure to anot......MORE |
Meta-analysis shows hepatitis C treatment is highly effective for drug usersKeith Alcorn | 6 years ago Direct-acting antiviral treatment is highly effective at curing hepatitis C in people who inje......MORE |
Study confirms STIs make no difference to undetectability and infectiousness in people taking HIV treatmentGus Cairns | 6 years ago A study conducted with gay men in Thailand has found that people who are diagnosed with HIV an......MORE |
Lymph node biopsies in individuals with acute HIV infection are safe and well-toleratedAlain Volny-Anne | 6 years ago Biopsies of lymph nodes in the groin, performed in the context of acute HIV infection, are saf......MORE |
Older age and baseline kidney function, not ARV choice, are key risk factors for chronic kidney disease in people with HIV in Australian cohortMichael Carter | 6 years ago Older age and lower baseline kidney function are the only significant risk factors for the dev......MORE |
PEPFAR funded 15 million medical male circumcisions between 2007 and 2017Gus Cairns | 6 years ago PEPFAR (the US President’s Emergency Fund for AIDS Relief) has supported the voluntary medic......MORE |
Loneliness associated with poorer cognitive function, mental health and physical health in older people with HIVMichael Carter | 6 years ago Loneliness in older HIV-positive adults is associated with reduced cognitive function as well ......MORE |
Racial segregation associated with new HIV infections among black heterosexuals living in the USKrishen Samuel | 6 years ago A greater degree of racial segregation in urban areas of the United States is associated with ......MORE |
Zoledronic acid is more effective than switching from tenofovir in HIV-positive people with low bone mineral densityAlain Volny-Anne | 6 years ago Two infusions of zoledronic acid resulted in significantly greater increases in bone mineral d......MORE |
"I approached him when he was in his good moods": how pregnant women introduce HIV self-tests to their partnersKeith Alcorn | 6 years ago Providing HIV self-testing kits to pregnant women to encourage HIV testing in their male partn......MORE |
Immunotherapy shows promise as a treatment for HIV-related Kaposi sarcomaMichael Carter | 6 years ago Immunotherapy may be an effective treatment for HIV-related Kaposi sarcoma (KS), according to ......MORE |
US doctors’ organisation endorses event-based PrEP for the first timeGus Cairns | 6 years ago For the first time, a US-based professional HIV body has published guidelines endorsing event-......MORE |
Do-it-yourself HIV prevention: who do men buying PrEP online get support from?Roger Pebody | 6 years ago Gay men in London who source their own supply of generic pre-exposure prophylaxis (PrEP) drugs......MORE |
Findings of large study suggest that HIV should be considered a major risk factor for cardiovascular diseaseMichael Carter | 6 years ago People living with HIV are twice as likely to develop cardiovascular disease (CVD), according ......MORE |
TB symptom screen less likely to detect active TB in people taking HIV treatmentKeith Alcorn | 6 years ago The four-symptom screen for active tuberculosis (TB) that is recommended for all people livin......MORE |
Stigma remains a substantial barrier in accessing HIV care in rural East AfricaKrishen Samuel | 6 years ago A set of varied barriers adversely impact positive outcomes at different stages in the HIV car......MORE |
High rates of smoking in people with HIV in sub-Saharan AfricaMichael Carter | 6 years ago Having HIV is associated with a greater likelihood of cigarette smoking and using smokeless to......MORE |
Two new doravirine pills approved in USLiz Highleyman | 6 years ago The US Food and Drug Administration (FDA) has approved two new products containing the next-ge......MORE |
Developmental problems of children born to women with HIV linked to substance use and HIV, not antiretroviralsKeith Alcorn | 6 years ago Pre-term births and developmental problems in children born to mothers with HIV are associated......MORE |
Starting from here - what PrEP programmes can learn from circumcisionGus Cairns | 6 years ago Funders, health providers and advocates should take lessons from the rollout of voluntary medi......MORE |
What do older people living with HIV do to look after their own mental health?Roger Pebody | 6 years ago Older people living with HIV describe a range of strategies to maintain or improve their menta......MORE |
Peer support is crucial for many people living with HIVRoger Pebody | 6 years ago Social support from peers living with HIV is of a different nature to the support received fro......MORE |
Unstable housing associated with low CD4 cell count and detectable viral load for HIV-positive women in USMichael Carter | 6 years ago Unstable housing is associated with an increased risk of a detectable viral load and low CD4 c......MORE |
Modest improvements in HIV knowledge and disclosure beliefs after summer camp for adolescents living with HIV in the UKRoger Pebody | 6 years ago An evaluation of the summer camp organised by the Children’s HIV Association (CHIVA) for 12-......MORE |
Work to improve the HIV care continuum for black transgender women should concentrate on HIV diagnosisRoger Pebody | 6 years ago Less than half of black transgender women living with HIV in the United States are aware of th......MORE |
Poorer ART outcomes show need to prioritise older people in HIV test and treat programmesMichael Carter | 6 years ago HIV testing and treatment programmes in sub-Saharan Africa need to prioritise older individual......MORE |
HIV diagnoses in gay men in the UK decreased by a third in two yearsRoger Pebody | 6 years ago New HIV diagnoses in the UK have fallen again, with the greatest reduction seen in gay and bis......MORE |
Indonesia: tackling HIV in one of the world’s fastest-growing epidemicsGus Cairns | 6 years ago A prospective study that recruited a significant proportion of people newly diagnosed with HIV......MORE |
Some antiretroviral regimens associated with pre-term birth and low birth weightKeith Alcorn | 6 years ago Exposure to protease inhibitor (PI)-based regimens and non-nucleoside reverse transcriptase in......MORE |
One in three women in US survey have negative attitudes towards PrEPGus Cairns | 6 years ago A survey conducted by Planned Parenthood in the US state of Connecticut has found that althoug......MORE |
Appropriate pain management may have role in key HIV treatment outcomes, suggests US researchMichael Carter | 6 years ago Chronic pain was reported by a quarter of people living with HIV in an American study publishe......MORE |
The work of a couple: how gay men in relationships come to trust that “Undetectable = Untransmittable”Roger Pebody | 6 years ago Having a relationship based on trust, commitment and familiarity helps Australian gay men rely......MORE |
PrEP for female sex workers: non-judgemental attitudes and community involvement are keys to successGus Cairns | 6 years ago Several studies presented at the 22nd International AIDS Conference (AIDS 2018) in Amsterda......MORE |
Europe close to meeting UNAIDS 90-90-90 target but considerable variability between countriesMichael Carter | 6 years ago The European region of the World Health Organization (WHO) is close to achieving the UNAIDS 90......MORE |
Dolutegravir-based ART effective and safe for HIV-positive people taking standard TB treatmentMichael Carter | 6 years ago Dolutegravir-based antiretroviral therapy (ART) is effective and safe when taken at the same t......MORE |
Breastfeeding with undetectable viral load: genuine uncertainty on risk should be communicated to women with HIV, say Swiss doctorsKeith Alcorn | 6 years ago Women with HIV on effective antiretroviral treatment in higher-income settings who have undet......MORE |
Neuropsychiatric side-effects lead only 1 in 40 to drop dolutegravir, French study showsKeith Alcorn | 6 years ago A large French study of people taking HIV treatment that contained an integrase inhibitor foun......MORE |
Giving gay men self-test kits increases testing by 50% - but STI tests decreaseGus Cairns | 6 years ago Gay men who were offered HIV home-testing kits took 50% more tests than men who only took HIV ......MORE |
UK research shows that black patients of West African and Caribbean origin have higher rates of chronic kidney diseaseMichael Carter | 6 years ago The risk of chronic and end-stage kidney disease among HIV-positive people of African ethnicit......MORE |
Starting treatment on the day of HIV diagnosis is acceptable and feasible for Thai patientsKeith Alcorn | 6 years ago Starting treatment on the day of HIV diagnosis is acceptable and feasible for Thai patients, a......MORE |
One in nine people may be able to control their viral load after stopping treatment, US study findsGus Cairns | 6 years ago A US collaboration that pooled data from 14 scientific studies containing between them more th......MORE |
People taking a protease inhibitor who have heart failure have an increased mortality risk, study claimsMichael Carter | 6 years ago HIV-positive people who are taking antiretroviral therapy (ART) and are hospitalised due to he......MORE |
HIV and chronic HCV co-infection prevalence in England highest among MSMMichael Carter | 6 years ago Men who have sex with men (MSM) make up the majority of people with chronic hepatitis C virus ......MORE |
Treatment with modern antiretrovirals doesn't increase the risk of hypertensionMichael Carter | 6 years ago There is no strong evidence that treatment with antiretrovirals significantly increases the ri......MORE |
PrEP use taking off in Thailand and VietnamGus Cairns | 6 years ago Pre-exposure prophylaxis (PrEP) use is accelerating among men who have sex with men and transg......MORE |
People with HIV receiving methadone and HIV drugs spend less time with detectable viral loadKeith Alcorn | 6 years ago People on methadone maintenance treatment spent less time with a detectable viral load above 1......MORE |
Studies show dolutegravir monotherapy is an unsafe switch optionKeith Alcorn | 6 years ago Using dolutegravir alone, as maintenance treatment after achieving undetectable viral load on ......MORE |
HIV infection is a risk factor for liver fat accumulationLiz Highleyman | 6 years ago People living with HIV are about twice as likely to develop steatosis, or fat accumulation in ......MORE |
Diarrhoea continues to affect the quality of life of people with HIV in the modern treatment eraRoger Pebody | 6 years ago A meta-analysis of 38 clinical trials of antiretroviral therapies (ART) conducted in the past ......MORE |
PrEP spreads across Africa - slowlyGus Cairns | 6 years ago This year, 2018, will be the year that a really significant number of people in Africa started......MORE |
Young adults with life-long HIV have a higher risk of cancerLiz Highleyman | 6 years ago Adolescents and young adults who acquired HIV before or at birth had a 13-fold higher likeliho......MORE |
Increase in STIs in PrEP users is concentrated in a minority of men and is partly due to more STI screeningRoger Pebody | 6 years ago There were significant increases in bacterial sexually transmitted infections (STIs) in gay an......MORE |
Unintended pregnancies and desire for children: reproductive health needs of women living with HIVCarole Leach-Lemens | 6 years ago The needs for safe conception services and a wider choice of contraception for women living wi......MORE |
Dolutegravir brings faster viral suppression in late pregnancyCarole Leach-Lemens | 6 years ago Among 60 women presenting to routine antenatal clinics in Kampala, Uganda and Cape Town, South......MORE |
Most adolescent PrEP users in US are young womenLiz Highleyman | 6 years ago Only 1.5% of people who have used pre-exposure prophylaxis (PrEP) in the United States are age......MORE |
Reduced dose darunavir/ritonavir effective and safe for people switching while virally suppressedMichael Carter | 6 years ago A daily dose of the boosted protease inhibitor darunavir/ritonavir 400/100mg is at least as ef......MORE |
Digital innovations are promoting HIV testing and prevention to MSM in AsiaRoger Pebody | 6 years ago Innovative health promotion interventions engaging men who have sex with men (MSM) in south ea......MORE |
Doravirine maintains higher rate of virological suppression over darunavir/ritonavir though 96 weeks of follow-upMichael Carter | 6 years ago The experimental non-nucleoside reverse transcriptase inhibitor (NNRTI) doravirine was more ef......MORE |
Three-quarters of deaths of people with HIV in London are due to non-AIDS conditionsRoger Pebody | 6 years ago Over three-quarters of deaths of people with HIV in London are due to non-AIDS conditions, wit......MORE |
Supervised drug consumption sites offer opportunities for HCV testing and treatmentLiz Highleyman | 6 years ago Most supervised drug consumption facilities offer hepatitis C virus (HCV) testing and referral......MORE |
HIV linked to higher risk of heart failureLiz Highleyman | 6 years ago HIV infection is associated with a significantly increased risk of developing heart failure, b......MORE |
Series of HIV outbreaks in people who inject drugs shows that ‘complacency is the new problem’Roger Pebody | 6 years ago There have been outbreaks of rapid HIV transmission among people who inject drugs in Athens, B......MORE |
The kick that didn’t kill: first-ever randomised HIV cure study fails to eliminate infected cellsGus Cairns | 6 years ago One study whose results were eagerly awaited at the 22nd International AIDS Conference (AIDS 2......MORE |
PrEP use linked to fewer new HIV infections in US statesLiz Highleyman | 6 years ago As pre-exposure prophylaxis (PrEP) use continues to grow, epidemiological evidence is starting......MORE |
Civil society under threat: How can HIV advocates resist the impact?Lisa Power | 6 years ago Civil society organisations (CSOs) providing HIV services and advocacy to key populations and ......MORE |
HIV treatment services in African countries need to adapt to serve mobile and migrant populationsRoger Pebody | 6 years ago Health facilities must be responsive to the needs of mobile individuals and of migrants if the......MORE |
HIV elimination in gay men: what is working?Lisa Power | 6 years ago Substantial decreases in HIV diagnoses in key cities show the way to elimination of new HIV di......MORE |
Kaposi's sarcoma remains a concern for people with HIVLiz Highleyman | 6 years ago A small proportion of people living with HIV continue to develop Kaposi's sarcoma (KS), a canc......MORE |
Progress against HIV in young people lags behind as Africa's youth population growsKeith Alcorn | 6 years ago Africa is far off track in reducing new HIV infections among children and young people and is ......MORE |
High uptake of HIV testing when self-tests are offered to outpatients in MalawiRoger Pebody | 6 years ago Most models of HIV self-test distribution are based on community settings, but providing self-......MORE |
Test and treat studies show high rates of HIV diagnosis, viral suppressionKeith Alcorn | 6 years ago Two large studies of community-based universal test and treat campaigns to promote HIV diagnos......MORE |
Universal test and treat greatly improves retention in careKeith Alcorn | 6 years ago People who started HIV treatment in Swaziland under a universal test and treat policy were se......MORE |
Donor funding for HIV stalls, increasing pressure on high-burden countries to mobilise domestic resourcesLisa Power | 6 years ago Falling levels of donor government funding for HIV programmes threaten progress towards the 20......MORE |
Unprecedented hepatitis C infection rates seen in gay men in Amsterdam PrEP programmeGus Cairns | 6 years ago Regular hepatitis C testing among the HIV-negative gay men and other men who have sex with men......MORE |
Dolutegravir dual therapy works well for first-time HIV treatmentLiz Highleyman | 6 years ago A two-drug combination of dolutegravir (Tivicay) and lamivudine suppressed viral load as well ......MORE |
PrEP does not lower feminising hormone level in transgender womenLiz Highleyman | 6 years ago Using Truvada (tenofovir DF/emtricitabine) for HIV prevention does not lower levels of feminis......MORE |
Why are some countries slow to implement HIV treatment guidelines?Roger Pebody | 6 years ago Differences in countries’ economic prosperity and HIV prevalence do not explain the speed wi......MORE |
World experts publish consensus statement on the science of HIV in the context of criminal lawMatthew Weait | 6 years ago One of the most significant events at the 22nd International AIDS Conference (AIDS 2018) was t......MORE |
Rapid treatment initiation and less time with detectable HIV linked to falls in new HIV diagnoses in San Francisco and MelbourneKeith Alcorn | 6 years ago More rapid initiation of treatment after diagnosis – and the shortening of the period with d......MORE |
Dolutegravir-based ART recommended for all - if reliable contraception is availableKeith Alcorn | 6 years ago The World Health Organization (WHO) has issued new antiretroviral treatment guidelines recomm......MORE |
Brazil confirms dolutegravir is the most effective drug for first-line HIV treatmentKeith Alcorn | 6 years ago People receiving dolutegravir-based antiretroviral treatment in Brazil’s national treatment ......MORE |
Dolutegravir: update on infant neural tube defects from BotswanaKeith Alcorn | 6 years ago Dolutegravir treatment at the time of conception is associated with a higher risk of neural tu......MORE |
On-demand dosing as effective as daily dosing in first year of French PrEP studyRoger Pebody | 6 years ago There have been no new HIV infections in the 1628 people taking part in a demonstration study ......MORE |
Zero transmissions mean zero risk - PARTNER 2 study results announcedGus Cairns | 6 years ago The chance of any HIV-positive person with an undetectable viral load transmitting the virus t......MORE |
Criminalisation of HIV high on agenda at AIDS 2018Matthew Weait | 6 years ago Strategies to oppose the unscientific criminalisation of HIV transmission received a high prof......MORE |
The “Undetectable = Untransmittable” message goes global: I=I, N=N and B=BRoger Pebody | 6 years ago In Guatemala, the slogan is “Indetectable = Intransmisible” (I=I); in the Netherlands, it......MORE |
Kenyan women can distribute HIV self-test kits to their sexual partners without a significant risk of intimate partner violenceMichael Carter | 6 years ago The distribution of HIV self-testing kits by women to their sexual partners doesn't increase w......MORE |
Treatment with bedaquiline significantly reduces mortality among South African people with XDR- and MDR-TBMichael Carter | 6 years ago Bedaquiline-based regimens are associated with large reductions in mortality in people with dr......MORE |
Will an HIV vaccine that protected two-thirds of monkeys do the same for humans?Gus Cairns | 6 years ago Summary The Lancet last Friday published the 52-week results of APPROACH, an HIV vaccine whose......MORE |
PrEP@Home pilot shows monitoring PrEP without clinic visit is feasible and acceptableKeith Alcorn | 6 years ago A pilot project, PrEP@Home, reduced clinic visits to one a year and demonstrated that men who ......MORE |
Does U=U for breastfeeding mothers and infants? Researchers highlight unanswered questionsKeith Alcorn | 6 years ago Research is urgently needed to provide clear recommendations on breastfeeding to mothers with ......MORE |
Online HIV prevention programme reduces STIs by 40% in young men who have sex with menRoger Pebody | 6 years ago An interactive online programme, tailored to real-life contexts of ethnically diverse young Am......MORE |
Dolutegravir durable with high rates of viral suppression in people who experienced virological failure with older integrase inhibitorsMichael Carter | 6 years ago Antiretroviral regimens containing the integrase inhibitor dolutegravir are durable and achiev......MORE |
HIV is not the only risk - using condoms or getting tested can pose risks to trust and relationshipsRoger Pebody | 6 years ago Perceptions of risk are crucial in explaining why people do or do not make use of HIV-preventi......MORE |
Many taking PrEP in San Francisco not having recommended HIV and STI screensMichael Carter | 6 years ago Laboratory monitoring does not meet guideline standards in up to a third of people prescribed ......MORE |
Condom efficacy may have been underestimated, new CDC study suggestsGus Cairns | 6 years ago Summary – what's different about this analysis A new meta-analysis (Johnson) of the efficacy ......MORE |
Diabetes isn't adequately managed in women with HIV, says US researchMichael Carter | 6 years ago Optimum targets for control of type 2 diabetes are achieved in only 11% of women with HIV or a......MORE |
HIV self-testing is greatly preferred to clinic testing by young South African bi/gay menGus Cairns | 6 years ago Summary A study that gave HIV self-testing kits out to 127 mainly young men who have sex with m......MORE |
Efavirenz does not increase the risk of suicidal thoughts or depression in Ugandan adultsKeith Alcorn | 6 years ago Treatment with the antiretroviral drug efavirenz did not increase the risk of depressive sympt......MORE |
Rilpivirine better tolerated, less toxic and more durable than efavirenz in first-line ARTMichael Carter | 6 years ago Rilpivirine is better tolerated, less toxic and more durable than efavirenz when used as part ......MORE |
HIV-related factors not associated with increased risk of suicide among people with HIV in FranceMichael Carter | 6 years ago Approximately 4% of deaths among people with HIV in France are due to suicide, investigators r......MORE |
Nearly a quarter of people who want PrEP currently can’t get it, UK survey findsGus Cairns | 6 years ago Summary A study of pre-exposure prophylaxis (PrEP) use conducted throughout the UK by Public He......MORE |
Loss of lay counsellors leads to fall in HIV testing in KwaZulu-NatalKeith Alcorn | 6 years ago The withdrawal of lay counsellors from primary health clinics in KwaZulu-Natal led to a sharp ......MORE |
Early adopters of PrEP in Kenya and Uganda more likely to be male and olderRoger Pebody | 6 years ago It is feasible to offer pre-exposure prophylaxis (PrEP) as part of community-wide HIV testing ......MORE |
Transmitted drug resistance now less likely to harm HIV treatment options, US study findsKeith Alcorn | 6 years ago The rising prevalence of transmitted antiretroviral drug resistance in the United States is un......MORE |
Viral suppression reduces cancer risk but does not affect common cancersKeith Alcorn | 6 years ago People with HIV whose viral load has been fully suppressed for at least two years have a signi......MORE |
Syphilis and gonorrhoea cases at highest levels for decades, Public Health England confirmsGus Cairns | 6 years ago The latest sexually transmitted infections (STI) surveillance report from Public Health Englan......MORE |
Frailty in men with HIV linked with bone weakness, muscle loss and large waistMichael Carter | 6 years ago Frailty is twice as prevalent in middle-aged and elderly HIV-positive men as in their HIV-nega......MORE |
New TB cases occur rapidly among close contacts of people with pulmonary TBMichael Carter | 6 years ago The close contacts of people with active pulmonary tuberculosis (TB) have high rates of the di......MORE |
Gay men get less HIV but more STIs after starting PrEP, meta-analysis findsGus Cairns | 6 years ago A meta-analysis of 17 studies of HIV pre-exposure prophylaxis (PrEP) in gay men and other men ......MORE |
Healthcare providers missing opportunities to prescribe PrEP to patients at high risk of HIVMichael Carter | 6 years ago Healthcare providers are missing opportunities to prescribe pre-exposure prophylaxis (PrEP) to......MORE |
It’s not just HIV stigma - sexism, racism and poverty stigma commonly reported by women living with HIV in the United StatesRoger Pebody | 6 years ago Women living with HIV perceive many forms of stigma in addition to HIV-related stigma, accordi......MORE |
Rapid change in Australian gay men’s safer sex practices, from consistent condom use to PrEPRoger Pebody | 6 years ago A rapid increase in pre-exposure prophylaxis (PrEP) use by gay men in Melbourne and Sydney has......MORE |
Hepatitis B or raised liver enzymes predict liver toxicity when TB prevention drug is combined with HIV treatmentMichael Carter | 6 years ago The risk of liver toxicity in people with HIV taking antiretroviral therapy and isoniazid prev......MORE |
HIV-negative gay men uncomfortable relying on an undetectable viral load to prevent HIVRoger Pebody | 6 years ago Australian HIV-negative gay men express far more confidence in pre-exposure prophylaxis (PrEP)......MORE |
Many young MSM discontinue PrEPMichael Carter | 6 years ago A third of young men who have sex with men (MSM) who take pre-exposure prophylaxis (PrEP) disc......MORE |
Kidney function declines faster in men on HIV treatment than for their HIV-negative peersKeith Alcorn | 6 years ago Loss of kidney function in men with HIV is most strongly associated with antiretroviral therap......MORE |
Potential interactions between ART and other medications present in over half of older HIV-positive peopleMichael Carter | 6 years ago Over half of older HIV-positive people are at risk of experiencing an interaction between thei......MORE |
High prevalence of high-risk opioid prescribing among HIV-positive adults in the USMichael Carter | 6 years ago There is a high prevalence of prescription opioid use among HIV-positive people, with many ind......MORE |
‘Risky when young’ or ‘risky with age’: Dutch study identifies life patterns associated with higher HIV risk in gay menGus Cairns | 6 years ago A Dutch study which looked at the way gay men’s risk of HIV changed with time has used stati......MORE |
Gay men having chemsex are five times more likely to have a new HIV diagnosis than other gay menRoger Pebody | 6 years ago Gay and bisexual men who reported engaging in chemsex (the use of specific drugs to enhance or......MORE |
PrEP may make it hard to tell if someone has an HIV infectionGus Cairns | 6 years ago It may be very difficult to tell if someone who has just started HIV pre-exposure prophylaxis ......MORE |
Dolutegravir may cause birth defects, European Medicines Agency warnsKeith Alcorn | 6 years ago Regulatory agencies in the United States and European Union have warned that women with HIV wh......MORE |
PrEP approved for adolescents in USLiz Highleyman | 6 years ago The US Food and Drug Administration (FDA) last week approved Truvada pre-exposure prophylaxis ......MORE |
High prevalence of menopausal symptoms in women living with HIV, but very few receive treatments for themRoger Pebody | 6 years ago Nine in ten women living with HIV aged 45 to 60 have hot flushes and other somatic symptoms of......MORE |
Do fatigue and quality of life improve after hepatitis C is cured?Keith Alcorn | 6 years ago Patient-reported outcomes such as fatigue, vitality and mental health improve substantially in......MORE |
Taking large numbers of non-ART drugs associated with increased risk of hospitalisation and death for HIV-positive peopleMichael Carter | 6 years ago Taking large numbers of medications in addition to antiretroviral therapy (ART) is associated ......MORE |
Living with HIV more than doubles the risk of erectile dysfunction in middle-aged MSMMichael Carter | 6 years ago Living with HIV is an independent risk factor for erectile problems among middle-aged men who ......MORE |
HIV may increase the risk of skin cancerMichael Carter | 6 years ago People living with HIV may have an increased risk of some types of skin cancer, Danish researc......MORE |
HIV cannot be transmitted by spitting, and risk from biting is negligible, says detailed case reviewMichael Carter | 6 years ago There is no risk of transmitting HIV through spitting, and the risk from biting is negligible,......MORE |
Prostate cancer and lung cancer projected to be most frequent cancer diagnoses in people with HIV by 2030Keith Alcorn | 6 years ago Prostate and lung cancer will become the most frequently diagnosed cancers in people living wi......MORE |
HIV outbreak among people who inject drugs in Glasgow now involves over 100 infections, many homelessMichael Carter | 6 years ago An HIV outbreak among people who inject drugs in Glasgow involves over 100 cases and is still ......MORE |
Mother-to-child HIV transmission at all-time low in the UK but around two-thirds of reported cases involve women diagnosed after deliveryMichael Carter | 6 years ago Factors such as uncertain immigration status, housing problems and intimate partner violence a......MORE |
Why aren’t older people tested for HIV? Views from doctors and patientsRoger Pebody | 6 years ago Limited knowledge of HIV and stereotypes about who may have HIV are barriers to HIV testing in......MORE |
NHS England saved £10 million by switching to generic anti-HIV drugs in 2016Roger Pebody | 6 years ago A programme to encourage clinicians to switch people to generic antiretroviral drugs saved the......MORE |
Hepatitis A causes less severe disturbances in liver function in people with HIV but illness lasts longerMichael Carter | 6 years ago Acute hepatitis A is less severe in people with HIV but takes longer to resolve, investigators......MORE |
What are the outcomes for adults who were born with HIV?Roger Pebody | 6 years ago Among people who were born with HIV and have now transitioned to adult care at St Mary’s hos......MORE |
Far more harms associated with crystal meth than other chemsex drugsRoger Pebody | 6 years ago Gay men who use crystal methamphetamine during sex are five times as likely to report a negati......MORE |
HIV diagnoses in Brighton started to fall before London and for different reasonsRoger Pebody | 6 years ago New HIV diagnoses in Brighton & Hove have fallen by half since 2013, according to a poster......MORE |
1600 people taking PrEP in Scotland and Wales, almost all are gay menRoger Pebody | 6 years ago “Welcome to a country where we do have a full NHS-delivered programme for PrEP, with no uppe......MORE |
Loneliness and isolation top list of unmet social needs among people living with HIV in the UKRoger Pebody | 6 years ago A survey of a large, representative sample of people attending HIV clinics in England has iden......MORE |
Routine clinical use of DAAs highly effective and safe in people with HIV/HCV in EuropeMichael Carter | 6 years ago “Real life” data from across Europe shows that direct-acting antivirals (DAAs) cure hepati......MORE |
Curing hepatitis C reduces deaths and liver diseaseKeith Alcorn | 6 years ago Curing hepatitis C infection significantly reduces deaths from liver disease and reduces the ......MORE |
Researchers puzzle over whether HIV accelerates cancer progressionLiz Highleyman | 6 years ago Although people living with HIV may be diagnosed with cancer at an earlier stage because they ......MORE |
Direct-acting antivirals bring fewer HCV-related liver transplants, better survival after transplantation, in EuropeMichael Carter | 6 years ago There has been a steep fall in the number of hepatitis C virus (HCV)-related liver transplants......MORE |
Eight weeks of treatment with Epclusa cured almost all people with HCV receiving opioid substitution therapyKeith Alcorn | 6 years ago An eight-week course of sofosbuvir/velpatasvir (Epclusa) cured almost all people with hepatiti......MORE |
New affordable hepatitis C combination shows 97% cure rateKeith Alcorn | 6 years ago The combination of sofosbuvir and the new NS5A inhibitor ravidasvir cured 97% of people with ......MORE |
First-line ART failure common among hospitalised HIV-positive people in sub-Saharan AfricaMichael Carter | 6 years ago A large proportion of hospitalised HIV-positive people in sub-Saharan Africa have experienced ......MORE |
More time with depression increases the risk of death for women with HIVMichael Carter | 6 years ago Increased time living with depression is associated with a higher risk of death for women with......MORE |
TAF only superior to TDF when used with a boosting agentMichael Carter | 6 years ago The benefits of tenofovir alafenamide (TAF) over tenofovir disoproxil fumarate (TDF) may have ......MORE |
Non-consensual sex is a recurrent problem in the chemsex environmentRoger Pebody | 6 years ago The second European Chemsex Forum, recently held in Berlin, highlighted a number of difficulti......MORE |
REALITY study shows which HIV-positive people with very low CD4 cell counts are at highest risk of dying soon after starting treatmentMichael Carter | 6 years ago Mortality in people with a low CD4 cell count at the time of HIV diagnosis is associated with ......MORE |
8-week course of Zepatier cures acute HCV in people with HIVLiz Highleyman | 6 years ago An 8-week course of grazoprevir/elbasvir (Zepatier) produced sustained virological response in......MORE |
The chemsex response is reshaping sexual health services and reinventing harm reductionRoger Pebody | 6 years ago Chemsex has led the French community-based HIV organisation AIDES to bring two previously sepa......MORE |
Loneliness and community are key to chemsexRoger Pebody | 6 years ago The second European Chemsex Forum, recently held in Berlin, highlighted how the perspectives o......MORE |
Integrase inhibitors do not raise risk of IRIS in severely immunocompromised peopleLiz Highleyman | 6 years ago Use of an integrase inhibitor, which can bring down viral load rapidly, was not associated wit......MORE |
South Africa: women may have higher rates of HIV than men because fewer men are on treatmentGus Cairns | 6 years ago South African researchers presenting a study at the recent Conference on Retroviruses and Oppo......MORE |
Switching from abacavir to TAF improves platelet functionLiz Highleyman | 6 years ago People who switched from an antiretroviral regimen containing abacavir to one containing tenof......MORE |
Research sheds more light on cardiovascular risk in people with HIVLiz Highleyman | 6 years ago People with HIV are more likely to develop cardiovascular conditions, including atherosclerosi......MORE |
Older people in United States more likely to have AIDS at the time of HIV diagnosisMichael Carter | 6 years ago People with HIV aged 60 and over in the United States are more than twice as likely to have an......MORE |
Age difference in HIV infection matters - but it’s not always the younger person who is at riskGus Cairns | 6 years ago A European study of men who have sex with men (MSM) presented at the recent Conference on Retr......MORE |
New South Wales puts 9000 people on PrEP, achieves a one-third decline in new HIV infectionsGus Cairns | 6 years ago The state of New South Wales in Australia has seen a fall of one-third in diagnoses of recent ......MORE |
Failure of second-line ART is common in resource-limited countries, but modern third-line regimens work wellLiz Highleyman | 6 years ago More than half of people in low- and middle-income countries may not maintain viral suppressio......MORE |
Lesotho making strong progress towards 90-90-90 targetsCarole Leach-Lemens | 6 years ago Lesotho, in spite of a high HIV prevalence of over 25%, is making substantial progress toward ......MORE |
Treatment with extended-release naltrexone increases chances that HIV-positive prisoners will maintain viral suppression after releaseMichael Carter | 6 years ago Treatment with extended-release naltrexone is associated with improved viral suppression among......MORE |
Very early treatment in children limits the HIV reservoirKeith Alcorn | 6 years ago Very early HIV treatment in infants is feasible and safe and leads to a small reservoir of inf......MORE |
Isoniazid preventive therapy: do the risks outweigh the benefits in pregnant women with HIV?Carole Leach-Lemens | 6 years ago Isoniazid preventive therapy (IPT) during and after pregnancy in women living with HIV on anti......MORE |
Powerful new PrEP and treatment drug should be effective as a small weekly pillGus Cairns | 6 years ago MK-8591 or EFdA is a novel and exceptionally long-lasting and potent HIV drug, being developed......MORE |
High uptake of HIV self-testing by men who have sex with men and transgender women in BurmaRoger Pebody | 6 years ago HIV self-testing is feasible and acceptable for men who have sex with men (MSM) and transgende......MORE |
Another likely case of PrEP 'breakthrough' infection reportedGus Cairns | 6 years ago A presentation at the recent 25th Conference on Retroviruses and Opportunistic Infections (CRO......MORE |
How much 'PrEP-resistant' HIV is out there?Gus Cairns | 6 years ago A study presented at the recent 25th Conference on Retroviruses and Opportunistic Infections (......MORE |
Efavirenz may undermine effectiveness of the vaginal ring contraceptiveKeith Alcorn | 6 years ago The antiretroviral drug efavirenz significantly reduces the levels of both hormones in the vag......MORE |
Ibalizumab, active against highly resistant HIV, now approved in USLiz Highleyman | 6 years ago Ibalizumab, a long-acting monoclonal antibody that prevents HIV from entering cells, is active......MORE |
Statin users have lower rates of many types of cancerLiz Highleyman | 6 years ago Both HIV-positive and HIV-negative people who use statins to manage cardiovascular disease ris......MORE |
The vaginal ring: more HOPE to the DREAM? Higher adherence and better effectiveness seen in open-label ring studiesGus Cairns | 6 years ago Two open-label, parallel studies of vaginal rings used to prevent HIV in women released interi......MORE |
PrEP use growing in US, but not reaching all those in needLiz Highleyman | 6 years ago The number of people taking HIV pre-exposure prophylaxis (PrEP) in the United States is steadi......MORE |
Twice-daily dolutegravir is safe and effective when used alongside TB treatmentKeith Alcorn | 6 years ago Twice-daily dosing of dolutegravir when combined with the tuberculosis (TB) drug rifampicin i......MORE |
Biktarvy combo maintains viral suppression after switching therapyLiz Highleyman | 6 years ago People who switched to a single-tablet regimen containing the integrase inhibitor bictegravir ......MORE |
Average time from HIV diagnosis to treatment fell to six days in 2016 in San FranciscoKeith Alcorn | 6 years ago The average time from HIV diagnosis to treatment initiation in San Francisco shrank from 35 da......MORE |
Transgender women in Los Angeles are more likely to be in high HIV incidence clusters than any other groupGus Cairns | 6 years ago A phylogenetic study of HIV infections in Los Angeles has found that transgender women (TGW) a......MORE |
Same-day treatment start improves retention in care and viral suppression in LesothoKeith Alcorn | 6 years ago Starting treatment at home, on the day of diagnosis, proved acceptable in rural Lesotho and re......MORE |
New HIV infections halved after scale-up of HIV treatment and circumcision in Uganda's hardest-hit districtMichael Carter | 6 years ago The rate of new HIV infections has halved since 2011 in a Ugandan community following large in......MORE |
Antiretroviral drug levels in hair strongly predict viral suppressionLiz Highleyman | 6 years ago Antiretroviral drug levels in a sample of hair were the strongest predictor of response to HIV......MORE |
One-month TB prevention regimen just as effective as 9-month regimenKeith Alcorn | 6 years ago A one-month course of the antibiotic rifapentine combined with isoniazid was just as effective......MORE |
US genotyping survey finds rapid HIV infection rate in young and Latino gay menGus Cairns | 6 years ago A US study of HIV gene sequences in networks with a particularly high HIV infection rate has f......MORE |
New TB screening methods cut deaths in people with HIVKeith Alcorn | 6 years ago Screening for tuberculosis (TB) and intensified follow-up of TB cases in people starting antir......MORE |
Experimental antibody plus TLR7 agonist maintains viral suppression in monkeysLiz Highleyman | 6 years ago Treatment with a broadly neutralising antibody plus an immune-stimulating drug led to long-ter......MORE |
Study finds that women are much more vulnerable to HIV infection during pregnancy and in the months after giving birthGus Cairns | 6 years ago A study presented today at the Conference on Retroviruses and Opportunistic Infections (CROI 2......MORE |
US studies underline importance of primary care physicians for people with HIVKeith Alcorn | 6 years ago People with HIV who have other medical conditions such as high blood pressure or high lipids a......MORE |
Intimate partner violence a major contributor to HIV epidemic among MSM in China, shows studyMichael Carter | 6 years ago HIV prevention programmes targeted at men who have sex with men (MSM) should include intimate ......MORE |
Chronic depression leads to poorer engagement with key stages of HIV care continuum, say US researchersMichael Carter | 6 years ago Increased time spent living with depression is associated with poorer engagement with the HIV ......MORE |
HIV prevention: It’s time to stop accepting the status quo, PrEP Summit concludesGus Cairns | 6 years ago The biggest barrier to HIV pre-exposure prophylaxis (PrEP) becoming more available and more wi......MORE |
Smoking threatens health gains from hepatitis C treatment, US researchers warnKeith Alcorn | 6 years ago People with hepatitis C in the United States are at least three times more likely to smoke tha......MORE |
Lymphoma treatment outcomes just as good for people with HIVKeith Alcorn | 6 years ago People with HIV treated for aggressive forms of non-Hodgkin lymphoma or Burkitt lymphoma appea......MORE |
Severe fibrosis improves in most people after hepatitis C cure but persists in a quarterMichael Carter | 6 years ago Hepatitis C virus (HCV)-related liver fibrosis improves significantly in the majority of peopl......MORE |
HPV16 highly prevalent among HIV-positive MSM in France and strongly associated with high-grade pre-cancerous anal lesionsMichael Carter | 6 years ago HIV-positive gay men in France have a very high prevalence of anal infection with strains of h......MORE |
PrEP does not raise lipids or alter body fat, safety study findsKeith Alcorn | 6 years ago Using pre-exposure prophylaxis (PrEP) does not raise lipid levels or have any substantial effe......MORE |
Zambia: HIV deaths on treatment underestimatedKeith Alcorn | 6 years ago People with HIV in Zambia were at least ten times more likely to die in the first two years af......MORE |
Darunavir/ritonavir most durable boosted protease inhibitor in European patients, especially those switching treatment for any reasonMichael Carter | 6 years ago Darunavir/ritonavir (DRV/r) is the most durable boosted protease inhibitor for antiretroviral ......MORE |
High prevalence of hypertension among HIV-positive people in the US with 'missed opportunities' for its diagnosis and controlMichael Carter | 6 years ago There is a high prevalence of hypertension among HIV-positive people in the United States and ......MORE |
Communication skills training for healthcare workers improves HIV treatment adherenceKeith Alcorn | 6 years ago People with HIV in Tanzania were more likely to report problems with non-adherence to antiretr......MORE |
US regulators approve new HIV combo pill containing bictegravirLiz Highleyman | 6 years ago The US Food and Drug Administration (FDA) yesterday approved Biktarvy, Gilead Sciences' new si......MORE |
Generic drugs for HIV treatment may save money, but barriers to prescription make savings elusiveKeith Alcorn | 6 years ago The potential savings from prescribing generic antiretrovirals predicted by economic models ma......MORE |
Reproductive health of HIV-positive women in Switzerland being neglected, says studyMichael Carter | 6 years ago HIV-positive women in Switzerland are mainly relying on male condoms for contraception, invest......MORE |
HIV-positive women starting antiretrovirals before conception have increased risk of having an infant that is small for gestational ageMichael Carter | 6 years ago HIV-positive women who take combination antiretroviral therapy (cART) before conception have a......MORE |
Harm reduction scale-up needed to eliminate HCV in people who inject drugs, European model predictsKeith Alcorn | 6 years ago Elimination of hepatitis C among people who inject drugs in Europe will require simultaneous s......MORE |
Risk of some non-AIDS cancers greater for people with HIV than others over 50Michael Carter | 6 years ago The risk of several cancers increases with age for older HIV-positive people, investigators fr......MORE |
NHS England seeks drug price cuts to eliminate hepatitis C by 2025Keith Alcorn | 6 years ago NHS England announced this week that it aims to eliminate hepatitis C by 2025 – if it can ne......MORE |
Viral suppression protects against long-term liver damage caused by older HIV drugsMichael Carter | 6 years ago A history of treatment with some older antiretroviral drugs can have a lasting negative impact......MORE |
Women with HIV less likely to receive recommended treatments for gynaecologic cancersMichael Carter | 6 years ago The majority of HIV-positive women diagnosed with gynaecological cancer do not receive treatme......MORE |
Despite numerous risk factors for HIV, a high proportion of Malawian adolescent girls and young women don't see themselves at riskMichael Carter | 6 years ago Many adolescent girls and young women with multiple risk factors for infection with HIV do not......MORE |
Less than half of adolescent girls and young women with HIV have suppressed viral load in eastern and southern AfricaKeith Alcorn | 6 years ago Less than half of adolescent girls and young women with HIV in some of the countries with the......MORE |
Smoking causes one in five cancers in people with HIV in North AmericaMichael Carter | 6 years ago A fifth of all cancers in people receiving HIV care in North America between 2000 and 2015 was......MORE |
Smoking reduces survival after liver cancer diagnosis for people with viral hepatitisKeith Alcorn | 6 years ago People with viral hepatitis who smoked were three times more likely to die after being diagno......MORE |
Long-acting injectable ARVs are convenient and private, study participants reportRoger Pebody | 6 years ago HIV-positive people who took injectable cabotegravir + rilpivirine every four or eight weeks a......MORE |
Hepatitis C treatment highly effective in harder-to-treat people with HIV co-infection, Spanish real-life study showsMichael Carter | 6 years ago Hepatitis C virus (HCV) treatment using direct-acting antivirals (DAAs) is highly effective and safe......MORE |
Attitudes towards men who ‘bareback’ are a barrier to wider use of PrEPRoger Pebody | 6 years ago Two new qualitative studies from Toronto shed light on how stigma affects the uptake of pre-exposure......MORE |
Faster action on adherence is needed after viral load becomes detectable, researchers warn global treatment programmesKeith Alcorn | 6 years ago Low-level HIV viral load, above the limit of detection, is an important warning signal for future tr......MORE |
People with HIV who are undiagnosed and those with detectable viral load less likely to use condoms, South African study findsMichael Carter | 6 years ago People with HIV who don't use condoms consistently are more likely to be unaware they are HIV-posit......MORE |
HIV-positive transgender men in US have significant unmet medical and social needsMichael Carter | 6 years ago HIV-positive transgender men in the United States have significant unmet social and healthcare need......MORE |
HIV drug resistance now high enough to trigger a change in first-line treatment in eastern and southern AfricaKeith Alcorn | 6 years ago HIV drug resistance is increasing rapidly in southern and eastern Africa and Latin America and, as......MORE |
ART reduces prevalence of cervical infection with high-risk HPV, pre-cancerous cell changes and cervical cancerMichael Carter | 6 years ago Antiretroviral therapy (ART) is associated with a lower prevalence of high-risk cervical HPV infect......MORE |
ART reduces prevalence of cervical infection with high-risk HPV, pre-cancerous cell changes and cervical cancerMichael Carter | 6 years ago Antiretroviral therapy (ART) is associated with a lower prevalence of high-risk cervical human papi......MORE |
Many Americans still get their HIV diagnosis years after infectionLiz Highleyman | 6 years ago Many people with HIV in the United States are still being diagnosed with HIV late, and therefore no......MORE |
HIV testing rate among children and adolescents boosted after caregivers receive a cash incentiveMichael Carter | 6 years ago Children and adolescents are more likely to be tested for HIV if their parents or caregivers are of......MORE |
HIV testing rate among children and adolescents boosted after care-givers receive a cash incentiveMichael Carter | 6 years ago Children and adolescents are more likely to be tested for HIV if their parents or caregivers are of......MORE |
More work and lower drug prices are needed to eliminate hepatitis C worldwideLiz Highleyman | 6 years ago Eliminating hepatitis C virus (HCV) as a global public health concern is feasible, but to do this m......MORE |
Sofosbuvir/ledipasvir for 8 weeks cures acute HCV in people with HIVLiz Highleyman | 6 years ago An 8-week course of sofosbuvir/ledipasvir (Harvoni) led to a sustained response in all people with ......MORE |
HIV-positive children in resource-limited settings can achieve good virological outcomes without routine viral load or CD4 cell count monitoringMichael Carter | 6 years ago HIV-positive children can achieve good virological outcomes without routine monitoring of CD4 cell ......MORE |
Undetectable viral load at time of immunisation enhances yellow fever vaccine protection for people with HIVMichael Carter | 6 years ago Viral suppression at the time of immunisation is the most important determinant of long-term respon......MORE |
To better target HIV prevention, identify people whose social contacts have high viral loadsRoger Pebody | 6 years ago Rather than relying on assessment of an individual’s sexual behaviour or of ‘community viral lo......MORE |
Despite reassuring data, we can’t yet say U=U for breastfeedingRoger Pebody | 6 years ago While effective HIV treatment greatly reduces the risk of onward transmission during breastfeeding,......MORE |
Risk of chronic kidney disease and cardiovascular disease in people with HIV should be assessed togetherMichael Carter | 6 years ago People with HIV should have their risk of cardiovascular disease (CVD) and chronic kidney disease (......MORE |
Schistosomiasis increases risk of infection with HIV, especially for women and is also associated with a higher HIV viral loadMichael Carter | 6 years ago Infection with schistosome parasitic worms has an important role in HIV transmission, especially fo......MORE |
Gay men’s stories of monogamy and non-monogamy: change, flexibility and tensionsRoger Pebody | 6 years ago Although some gay men idealise monogamy, particularly in the early stages of a relationship, couple......MORE |
European Cure Review concentrates on HIV therapeutic vaccinesGus Cairns | 6 years ago A cure for HIV would almost inevitably have to involve a vaccine to improve the body’s natural ab......MORE |
Who is taking an HIV test in England and where?Roger Pebody | 6 years ago The range of settings in which people test for HIV has expanded significantly in recent years in En......MORE |
HIV incidence is falling in English gay men, say Public Health EnglandRoger Pebody | 6 years ago While several recent reports have shown that new HIV diagnoses have been falling in UK gay men, wha......MORE |
Screen all HIV-positive MSM for pre-cancerous anal cell changes, say Dutch investigatorsMichael Carter | 6 years ago Younger age and shorter duration of viral suppression are risk factors for the development of high-......MORE |
Nivolumab improves outcomes in liver cancer studyLiz Highleyman | 6 years ago Nivolumab (Opdivo), a PD-1 checkpoint inhibitor that helps the immune system fight cancer, was asso......MORE |
No change in cognitive function or brain structure in people taking effective HIV treatment for 2 yearsKeith Alcorn | 6 years ago People with HIV taking antiretroviral treatment who had undetectable viral load did not suffer any ......MORE |
Up to a quarter of HIV-negative gay men attending three English clinics used PrEP in the last yearGus Cairns | 6 years ago A prospective cohort study of gay men attending three clinics in southern England – 56 Dean St an......MORE |
Healthcare workers living with HIV have different motivations for disclosing or concealing their HIV statusRoger Pebody | 6 years ago Nurses and other healthcare workers who are living with HIV have mixed reactions when they mention ......MORE |
HIV diagnoses in English gay men have been falling since 2014Gus Cairns | 6 years ago A new analysis by Public Health England of testing rates and HIV diagnoses from all of England’s ......MORE |
High HIV incidence from non-primary partners and low PEP and PREP use seen in PARTNER studyGus Cairns | 6 years ago HIV incidence among the HIV-negative gay men in the PARTNER 1 and 2 studies, due to sex with partne......MORE |
European AIDS Clinical Society strengthens HPV vaccination adviceKeith Alcorn | 6 years ago The European AIDS Clinical Society (EACS) has recommended HPV (human papillomavirus) vaccination fo......MORE |
People with HIV more likely to adhere to their antiretroviral therapy than treatment for other chronic health problemsMichael Carter | 7 years ago Ageing HIV-positive people have significantly higher levels of adherence to their antiretroviral th......MORE |
Starting ART immediately after HIV diagnosis cuts mortality risk by two-thirds for people with high CD4 cell countsMichael Carter | 7 years ago People with a high CD4 cell count who start antiretroviral therapy (ART) immediately after diagnosi......MORE |
Starting ART immediately after HIV diagnosis cuts mortality risk by two-thirds for patients with high CD4 cell countsMichael Carter | 7 years ago Patients with a high CD4 cell count who start antiretroviral therapy (ART) immediately after diagno......MORE |
Swiss study examines which years gay men decided to stop consistent condom useGus Cairns | 7 years ago An innovative study presented at the 16th European AIDS conference in Milan two weeks ago used a ma......MORE |
Survey of dating app users finds that PrEP usage has not increased in Europe in the last yearGus Cairns | 7 years ago A study of men who have sex with men (MSM) conducted by the European Centre for Disease Control and......MORE |
Global progress towards hepatitis C elimination still blocked by cost of treatment, lack of diagnosisKeith Alcorn | 7 years ago Nine countries — Australia, Brazil, Egypt, Georgia, Germany, Iceland, Japan, the Netherlands and ......MORE |
UK elimination of hepatitis C in jeopardy unless more patients foundKeith Alcorn | 7 years ago Just one in three people with hepatitis C in the United Kingdom has been diagnosed according to the......MORE |
Hepatitis C test-and-treat programme reduces HCV by two-thirds among men who have sex with Men in Swiss HIV CohortKeith Alcorn | 7 years ago A systematic policy of test-and-treat cured 99% of men who have sex with men with hepatitis C in th......MORE |
Curing hepatitis C with DAAs linked to 71% reduction in liver cancerLiz Highleyman | 7 years ago People who achieved a sustained response to hepatitis C treatment lowered their risk of hepatocellu......MORE |
High rate of hepatitis C reinfection in German men who have sex with menKeith Alcorn | 7 years ago Around one in seven gay and bisexual men cured of hepatitis C at major treatment centres in German......MORE |
Symtuza as effective as multi-pill combination in previously untreated people with HIVKeith Alcorn | 7 years ago The single-pill combination of darunavir, cobicistat, tenofovir alafenamide and emtricitabine (Symt......MORE |
Fostemsavir controls viral load in half of people with highly drug-resistant HIVKeith Alcorn | 7 years ago Fostemsavir, a new experimental attachment inhibitor, suppressed viral load in over half of partici......MORE |
Hepatitis C halved in Spanish people living with HIV in one year due to treatmentKeith Alcorn | 7 years ago Spain is making dramatic progress towards eliminating hepatitis C in people living with HIV because......MORE |
People with HIV still expect a lower quality of life than their negative peers, European survey findsGus Cairns | 7 years ago A study commissioned by the drug company Gilead Sciences and conducted in five European countries h......MORE |
New EACS treatment guidelinesKeith Alcorn | 7 years ago Everyone with HIV and HCV co-infection should receive direct-acting antiviral treatment for hepatit......MORE |
How a London clinic reduced new HIV infections by 90% and why more European cities can do the sameKeith Alcorn | 7 years ago Scaling up HIV testing to reduce undiagnosed HIV infection requires a fundamental re-ordering of HI......MORE |
ABX464 reduces HIV reservoir but doesn’t delay viral reboundKeith Alcorn | 7 years ago ABX464, a new drug that stimulates the clearance of HIV from infected cells, reduces the reservoir ......MORE |
Boosted protease inhibitor and lamivudine provides effective maintenance treatmentKeith Alcorn | 7 years ago HIV maintenance treatment with two drugs, a boosted protease inhibitor and lamivudine, is just as e......MORE |
Daily aspirin therapy linked to lower liver cancer riskLiz Highleyman | 7 years ago People with hepatitis B virus (HBV) who took an aspirin a day – often recommended to help prevent......MORE |
Hepatitis C testing linked to reduced opioid use among people who inject drugsLiz Highleyman | 7 years ago Getting tested for hepatitis C virus (HCV) was associated with reduced drug use, especially among t......MORE |
Maviret cures most people with HCV genotype 3 and those with cirrhosisLiz Highleyman | 7 years ago Glecaprevir and pibrentasvir, the two drugs in the recently approved Maviret co-formulation, demons......MORE |
HCV infection is rising among HIV-positive gay men in San DiegoLiz Highleyman | 7 years ago Hepatitis C incidence is increasing among gay and bisexual men living with HIV in San Diego, accord......MORE |
Hepatitis C cure leads to improved quality of lifeLiz Highleyman | 7 years ago People who were cured of hepatitis C with direct-acting antivirals (DAAs) had sustained improvement......MORE |
A year of generic PrEP could recoup its own cost within five years if effectiveness is high, Public Health England model findsGus Cairns | 7 years ago A cost-effectiveness model developed by Public Health England finds that just one year’s worth of......MORE |
PrEP would save the NHS money, in numerous scenariosRoger Pebody | 7 years ago A PrEP programme for men who have sex with men in the UK would not only be cost-effective, but actu......MORE |
Restrictions on free DAA access in many European countries contrary to guidelines and undermine HCV elimination targets, say researchersMichael Carter | 7 years ago The restrictions which many European countries impose on free/reimbursed access to hepatitis C viru......MORE |
MSM in London diagnosed with early syphilis are a priority group for PrEP, suggests UK studyMichael Carter | 7 years ago Gay and other men who have sex with men (MSM) recently diagnosed with early syphilis are a priority......MORE |
Symtuza protease inhibitor regimen maintains viral suppression for a yearLiz Highleyman | 7 years ago People who switched from a multi-pill antiretroviral regimen to the first one-pill, once-daily regi......MORE |
Long-acting monoclonal antibody effective against multidrug-resistant HIVLiz Highleyman | 7 years ago Ibalizumab, a long-acting monoclonal antibody that prevents HIV from entering cells, maintained vir......MORE |
Rapid fibrosis progression in large proportion of HIV-positive gay men after acute HCVMichael Carter | 7 years ago Over a third of HIV-positive gay men develop significant liver fibrosis after an episode of acute h......MORE |
Impact of side-effects on retention in HIV care is underestimated, African study suggestsKeith Alcorn | 7 years ago The impact of drug side-effects on retention in HIV care is probably being underestimated, accordin......MORE |
Impact of side effects on retention in HIV care is underestimated, African study suggestsKeith Alcorn | 7 years ago The impact of drug side effects on retention in HIV care is probably being underestimated, accordin......MORE |
Many gay/bisexual men currently taking PrEP would switch to injectable forms of the therapy should it become availableMichael Carter | 7 years ago Approximately a third of gay and bisexual men who are currently taking oral (tenofovir/emtricitabin......MORE |
People with HIV/HCV co-infection have an increased risk of cardiovascular disease compared to people with HIV aloneMichael Carter | 7 years ago People with HIV/hepatitis C virus (HCV) co-infection are between a quarter and a third more likely ......MORE |
HIV diagnoses in the UK fell in gay men last year for the first time since the mid-1990s, Public Health England confirmsGus Cairns | 7 years ago The 2016 HIV surveillance figures released by Public Health England (PHE) today reveal that what ha......MORE |
Virally-suppressed people have “effectively no risk” of transmitting HIV, says US CDC: but how many are suppressed?Gus Cairns | 7 years ago The US Centers for Disease Control and Prevention (CDC) used 27 September, National Gay Men’s HIV......MORE |
Virally suppressed people have “effectively no risk” of transmitting HIV, says US CDC: but how many are suppressed?Gus Cairns | 7 years ago The US Centers for Disease Control and Prevention (CDC) used 27 September, National Gay Men’s HIV......MORE |
Drinking three or more cups of coffee a day halves the risk of dying for people with HIV/HCV co-infectionMichael Carter | 7 years ago Drinking three or more cups of coffee a day halves the risk of death from any cause for people with......MORE |
Amsterdam PrEP failure patient had unusual course of HIV infectionGus Cairns | 7 years ago At last February’s Conference on Retroviruses and Opportunistic Infections (CROI), Dutch clinicia......MORE |
Depression highly prevalent among people living with HIV in sub-Saharan AfricaMichael Carter | 7 years ago Depression is very common among people living with HIV (PLHIV) in sub-Saharan Africa (SSA), accordi......MORE |
US FDA approves nivolumab immunotherapy for liver cancerLiz Highleyman | 7 years ago The US Food and Drug Administration (FDA) last week granted accelerated approval for nivolumab (Opd......MORE |
HIV diagnoses on the rise among over-50s in EuropeKeith Alcorn | 7 years ago Just over one in six people diagnosed with HIV in Europe between 2004 and 2015 was over 50 years of......MORE |
People living with HIV in the UK not receiving appropriate monitoring of heart disease riskMichael Carter | 7 years ago The majority of HIV-positive people in the UK are not receiving recommended monitoring of cardiovas......MORE |
Australian clinic records show significant reduction in duration of infectiousness in HIV-positive gay men from 2007-2016Michael Carter | 7 years ago The period during which HIV-positive men who have sex with men (MSM) are potentially infectious fel......MORE |
Marathon training is safe for people with HIVMichael Carter | 7 years ago Marathon run training is safe for people with HIV, investigators from Germany report in BMC Infecti......MORE |
Does drug injection equipment other than syringes transmit hepatitis C?Liz Highleyman | 7 years ago Sharing drug preparation paraphernalia may not significantly contribute to hepatitis C virus (HCV) ......MORE |
Smokers with HIV doing well on treatment now at greater risk of lung cancer than AIDSKeith Alcorn | 7 years ago People living with HIV on antiretroviral treatment with fully suppressed viral load who smoke are m......MORE |
San Francisco annual report shows continued drop in new HIV infectionsLiz Highleyman | 7 years ago The San Francisco Department of Public Health has released its HIV Epidemiology Annual Report for 2......MORE |
High prices of DAAs mean there's been little progress towards achieving WHO target of eliminating HCV by 2030Michael Carter | 7 years ago Only a handful of countries are on course to achieve the World Health Organization (WHO) target of......MORE |
Study documents changing opinion among Italian doctors about PrEPGus Cairns | 7 years ago A survey of Italian infectious disease physicians working with HIV, conducted in 2015 but only publ......MORE |
New guidelines recommend that women avoid tenofovir & emtricitabine during pregnancyKeith Alcorn | 7 years ago Women should be offered the choice to avoid treatment with tenofovir and emtricitabine during pregn......MORE |
New US PrEP cost-effectiveness model finds drug prices will need to drop substantially if HIV risk rises, or if adherence is only moderateGus Cairns | 7 years ago A new US model of the cost-effectiveness of pre-exposure prophylaxis (PrEP) for men who have sex wi......MORE |
Maraviroc matches boosted protease inhibitor treatment over 96 weeksMichael Carter | 7 years ago Treatment with maraviroc (Celsentri/Selzentry) is associated with durable HIV suppression and a fav......MORE |
What is going on in gay men’s lives when they acquire HIV?Roger Pebody | 7 years ago Gay men in England who have recently become HIV positive describe a complex web of factors which ma......MORE |
No new HIV infections among Kaiser PrEP users, but data shows missed opportunitiesLiz Highleyman | 7 years ago No new HIV infections have occurred among nearly 5000 people who started Truvada for pre-exposure p......MORE |
Lipids improved by switching from ritonavir to cobicistat as a booster for darunavirMichael Carter | 7 years ago Switching from ritonavir to cobicistat is associated with significant improvements in cholesterol a......MORE |
Case reports of severe dolutegravir-related depressionMichael Carter | 7 years ago Severe depression can be a side-effect of treatment with the anti-HIV drug dolutegravir. In HIV Med......MORE |
Experts concur that intermittent oral PrEP probably won’t work for womenGus Cairns | 7 years ago Two presentations at the recent International AIDS Society Conference on HIV Science (IAS 2017) in ......MORE |
Experts concur that event-related oral PrEP probably won’t work for womenGus Cairns | 7 years ago Two presentations at the recent International AIDS Society Conference on HIV Science (IAS 2017) in ......MORE |
Taking dolutegravir in the morning may avert insomniaKeith Alcorn | 7 years ago Italian doctors say that sleeplessness after taking the integrase inhibitor dolutegravir occurred m......MORE |
The availability of direct-acting antivirals is reducing disparities in the uptake of hepatitis C treatmentRoger Pebody | 7 years ago An analysis from British Columbia, Canada shows that older people, individuals with HIV co-infectio......MORE |
The availability of directly acting antivirals is reducing disparities in the uptake of hepatitis C treatmentRoger Pebody | 7 years ago An analysis from British Columbia, Canada shows that older people, individuals with HIV co-infectio......MORE |
Who are trans women acquiring HIV from?Gus Cairns | 7 years ago There is a lot we don’t know about trans women’s HIV risk, why they are so vulnerable to HIV an......MORE |
One in seven people offered PrEP in African study start it immediatelyGus Cairns | 7 years ago One in seven (14%) of people offered PrEP in a large community study of enhanced HIV testing and tr......MORE |
What is “successful ageing” for people living with HIV?Roger Pebody | 7 years ago When Canadian researchers asked HIV-positive people over the age of 50 how they would define “suc......MORE |
New South Wales reports record drop in HIV diagnoses: fewest this year since records beganGus Cairns | 7 years ago Australia’s most populous state, New South Wales (NSW), has reported a steep drop in HIV diagnose......MORE |
No evidence of reduced efficacy or increased side-effects when patients switch to generic drugs, comparison study findsRoger Pebody | 7 years ago An analysis of 440 people switched to generic antiretroviral drugs at an Italian clinic and a match......MORE |
Trans women wary of antiretroviral drug and hormone interactionsLiz Highleyman | 7 years ago Transgender women living with HIV may be hesitant to use antiretroviral therapy (ART) or not take i......MORE |
Liver fibrosis speeds up around the menopause in women with HIV and HCV co-infectionMichael Carter | 7 years ago Menopause is associated with accelerated liver fibrosis in women with HIV and hepatitis C virus (HC......MORE |
People with HIV are at risk for liver fibrosis and steatosisLiz Highleyman | 7 years ago Metabolic syndrome, type 2 diabetes and obesity are risk factors for the development of liver fibro......MORE |
Switching from efavirenz to raltegravir leads to significant improvements in fatty liver disease in people with HIVMichael Carter | 7 years ago Switching to raltegravir from efavirenz is associated with significant improvements in liver steato......MORE |
Peripheral artery disease more common in people with HIV with lower CD4 countsKeith Alcorn | 7 years ago Peripheral artery disease, one of the most common forms of cardiovascular disease, occurs more freq......MORE |
PrEP use in US exceeds 100,000 in Gilead pharmacy surveyLiz Highleyman | 7 years ago An estimated 120,000 people in the US have started Truvada for pre-exposure prophylaxis (PrEP) sinc......MORE |
Incidence of anal cancer has already peaked among HIV-positive gay men; reductions can be achieved with expanded ART coverage and screeningMichael Carter | 7 years ago The incidence of anal cancer among HIV-positive gay men peaked in 2009 and will decline substantial......MORE |
Treatment with DAAs reduces the risk of mortality in the first 18 months after the completion of treatmentMichael Carter | 7 years ago For the first time, a large study has demonstrated that treatment with direct-acting antivirals (DA......MORE |
Switch from boosted protease inhibitor to dolutegravir reduces lipids in people with HIV at higher risk of heart diseaseKeith Alcorn | 7 years ago Switching from a boosted protease inhibitor to the integrase inhibitor dolutegravir was associated ......MORE |
Boosted darunavir plus lamivudine matches three-drug regimenKeith Alcorn | 7 years ago A combination of darunavir/ritonavir and lamivudine was just as effective as the same combination p......MORE |
European and US regulators approve AbbVie's new combo for all hepatitis C genotypesLiz Highleyman | 7 years ago The European Commission and the US Food and Drug Administration (FDA) last week approved AbbVie's n......MORE |
PrEP demand in England is rapidly accelerating – and most will want to join the trialGus Cairns | 7 years ago A survey of people currently using pre-exposure prophylaxis (PrEP) has found that PrEP use has rapi......MORE |
Why curing HIV may be like curing cancer – and may be as difficultGus Cairns | 7 years ago For the last few years, a specialist symposium on HIV cure research has preceded the International ......MORE |
What marks out HIV controllers from others?Gus Cairns | 7 years ago What if we are asking the wrong, question, though? What if trying to destroy or at least expose and......MORE |
Can we achieve a complete HIV cure in more patients?Gus Cairns | 7 years ago What all the different approaches discussed in the previous report have in common is to put HIV inf......MORE |
VRC01 antibody can delay but not prevent viral rebound after interruption of early treatmentLiz Highleyman | 7 years ago A broadly neutralising antibody modestly delayed the resurgence of viral replication following inte......MORE |
Long-acting NRTI shows promise for HIV treatment and PrEPLiz Highleyman | 7 years ago A single oral dose of MK-8591, a long-acting antiretroviral in a novel drug class, suppressed HIV f......MORE |
Stillbirth more frequent in women with HIV in UK and Ireland than in general populationCarole Leach-Lemens | 7 years ago The stillbirth rate among women living with HIV in the UK and Ireland from 2007 to 2015 was more th......MORE |
US HIV funding decisions on PEPFAR in 2017 will have critical effect on ability to reach 90-90-90 goalsKeith Alcorn | 7 years ago A withdrawal of United States funding for HIV treatment and prevention in sub-Saharan Africa could ......MORE |
First protease inhibitor combination pill maintains viral suppressionLiz Highleyman | 7 years ago The first once-daily single-tablet regimen containing a protease inhibitor maintained viral suppres......MORE |
Adolescents with HIV do better in more prosperous African countries, even with treatmentCarole Leach-Lemens | 7 years ago Adolescents who acquired HIV perinatally were less likely to die, grew faster and had better immune......MORE |
France’s next PrEP study aims to assess the wider impact of PrEP on the HIV epidemicRoger Pebody | 7 years ago France is launching a new study which will enrol 3000 new pre-exposure prophylxis (PrEP) users over......MORE |
Dutch study finds out whether gay men prefer daily or on-demand PrEPGus Cairns | 7 years ago In Europe, whether through national programmes or in trials, people are more often than not being g......MORE |
Long-acting cabotegravir injection shows promise for HIV preventionLiz Highleyman | 7 years ago A long-acting injectable formulation of cabotegravir given every 8 weeks produces high enough drugs......MORE |
Doravirine combination pill looks good for initial HIV treatmentLiz Highleyman | 7 years ago A single-tablet regimen containing the next-generation NNRTI doravirine reduced HIV viral load as m......MORE |
Acute kidney injury ‘uncommon’ but unpredictable on tenofovir and ritonavirGus Cairns | 7 years ago Doctors need to monitor patients regularly for kidney function if they are taking tenofovir, especi......MORE |
Countries and donors should aim for new $90-$90-$90 target on HIV, hepatitis, TB drug prices, study showsKeith Alcorn | 7 years ago HIV, hepatitis B and C and tuberculosis can each be treated for less than $90 a year where generic ......MORE |
Medical male circumcision for HIV has benefits for women tooRoger Pebody | 7 years ago South African women whose most recent sexual partner was circumcised are less likely to have HIV, s......MORE |
Demonstration projects explore the feasibility of PrEP for adolescents and young women in South AfricaRoger Pebody | 7 years ago One of the first studies to explore the acceptability, safety and use of pre-exposure prophylaxis (......MORE |
Ipergay trial: PrEP still protected people who had less sex and used it less oftenGus Cairns | 7 years ago A substudy of the French Ipergay trial of ‘on-demand’ PrEP has found that PrEP was just as effe......MORE |
Another HIV vaccine efficacy trial will start this yearGus Cairns | 7 years ago A year ago, one of the biggest pieces of prevention news at the Durban International AIDS Conferenc......MORE |
Glecaprevir/pibrentasvir is effective for people with HIV/HCV co-infectionLiz Highleyman | 7 years ago AbbVie's new pangenotypic regimen combining glecaprevir and pibrentasvir cured almost all HIV-posit......MORE |
90-90-90 progress in southern Africa: HIV testing gap needs to be closed in young people and menKeith Alcorn | 7 years ago Three African countries with high burdens of HIV infection are achieving very high levels of HIV tr......MORE |
Can self-testing engage 'hard to reach' men with HIV testing?Roger Pebody | 7 years ago Adding HIV self-testing as an additional option to a door-to-door programme offering HIV testing in......MORE |
Integrase inhibitors not causing higher rates of adverse birth outcomes, Botswana and French studies showCarole Leach-Lemens | 7 years ago Dolutegravir-based antiretroviral therapy (ART) started in pregnancy is as safe as efavirenz-based ......MORE |
New guidance says start HIV treatment within 7 days of diagnosis – but is everyone ready?Keith Alcorn | 7 years ago Everyone diagnosed with HIV should be offered the option to start treatment within seven days of di......MORE |
International study of gay couples reports no transmissions from an HIV-positive partner on treatmentGus Cairns | 7 years ago A study of 343 gay couples, where one partner had HIV and the other did not, has not found a single......MORE |
New integrase inhibitor bictegravir works well for first-line HIV treatmentLiz Highleyman | 7 years ago A single-tablet regimen containing the experimental integrase inhibitor bictegravir was as effectiv......MORE |
Hepatitis C treatment is effective and feasible in AfricaLiz Highleyman | 7 years ago Treatment for hepatitis C in sub-Saharan Africa can produce cure rates as high as those seen in ind......MORE |
High uptake of HIV self testing by female sex workers in African countriesRoger Pebody | 7 years ago A year ago there was virtually no evidence on the acceptability and feasibility of HIV self testing......MORE |
South African child has controlled HIV off treatment for 8.5 yearsKeith Alcorn | 7 years ago A nine-year-old South African child who was diagnosed with HIV infection at one month of age and r......MORE |
Programme to provide free self tests helps gay men to test for HIV more oftenRoger Pebody | 7 years ago Providing free HIV self-testing kits to gay and bisexual men is an effective way to increase the fr......MORE |
Less frequent clinic visits for HIV care: fine tuning neededKeith Alcorn | 7 years ago Shifts to less frequent clinic visits and medication pick-ups to free up healthcare resources and ......MORE |
Improved treatment for cryptococcal meningitis in HIV could save thousands of lives – if generic drug becomes availableKeith Alcorn | 7 years ago Urgent action is needed to improve access to the antifungal drug flucytosine, say investigators, fo......MORE |
Swaziland: new infections halved in five years as HIV treatment scales upKeith Alcorn | 7 years ago New HIV infections have halved in Swaziland since 2011 at the same time as the proportion of people......MORE |
Long-acting cabotegravir + rilpivirine injection shows good results at 96 weeksLiz Highleyman | 7 years ago Two long-acting injectable antiretrovirals, cabotegravir and rilpivirine, administered once every 4......MORE |
London gonorrhoea rates fall, and HIV rates falling in Australia as more join PrEP demoGus Cairns | 7 years ago Gonorrhoea diagnoses among gay men attending the largest STI clinic in the UK at 56 Dean Street in ......MORE |
World on track to reach the 90-90-90 targets for HIV treatment by 2020Keith Alcorn | 7 years ago The world is on track to reach global targets for reducing AIDS deaths and HIV treatment access by ......MORE |
WHO recommends package of tests, treatment and prevention for 'urgent need' people with HIV with low CD4 countsKeith Alcorn | 7 years ago A new package of measures to ensure rapid initiation of antiretroviral treatment and diagnosis of o......MORE |
Few people with HIV starting raltegravir and dolutegravir change therapy because of side-effectsMichael Carter | 7 years ago Only a few people starting an integrase inhibitor discontinue the treatment during the first year o......MORE |
US regulator approves Gilead's Vosevi combo pill for hepatitis C retreatmentLiz Highleyman | 7 years ago On 18 July the US Food and Drug Administration (FDA) approved Gilead Sciences' Vosevi, a new once-d......MORE |
US regulators approves Gilead's Vosevi combo pill for hepatitis C re-treatmentLiz Highleyman | 7 years ago On July 18 the US Food and Drug Administration (FDA) approved Gilead Sciences' Vosevi, a new once-d......MORE |
Many people living with HIV at high risk of cardiovascular disease are not on statinsMichael Carter | 7 years ago Only half of HIV-positive patients at a Chicago clinic eligible for statin therapy according to the......MORE |
People treated with atazanavir had lower risk of stroke and heart attackKeith Alcorn | 7 years ago People who started HIV treatment with a drug combination containing atazanavir (Reyataz) were signi......MORE |
Gay men using HIV self-tests promptly seek confirmatory testing and linkage to care, New York data suggestsRoger Pebody | 7 years ago Data from the partner services programme in New York City suggests that gay men who have previously......MORE |
Proton pump inhibitors may blunt CD4 cell gains, cause immune activation, in people with HIVKeith Alcorn | 7 years ago Proton pump inhibitors should be used with caution in people with HIV, US researchers say, after fi......MORE |
Non-alcoholic fatty liver disease common in people living with HIV – metabolic disorders are key risk factorsMichael Carter | 7 years ago Over a third of people with HIV have non-alcoholic fatty liver disease (NAFLD) in the absence of he......MORE |
High uptake of home-based HIV testing in Zambia, but repeat visits needed to get close to universal coverageRoger Pebody | 7 years ago Preliminary results from PopART, a large-scale study of a universal test and treat approach to slow......MORE |
Frailty is associated with loss of bone mineral density in middle-aged HIV-positive men and womenMichael Carter | 7 years ago Frailty is associated with loss of bone mineral density (BMD) in HIV-positive people, investigators......MORE |
Curing hepatitis C improves diabetes controlKeith Alcorn | 7 years ago Curing hepatitis C infection with direct-acting antiviral treatment improves diabetes control in pe......MORE |
Viral load as low as 400 copies/ml six months after starting ART is associated with a significant ten-year mortality riskMichael Carter | 7 years ago A viral load as low as 400 copies/ml six months after starting HIV therapy is associated with a sub......MORE |
Hepatitis A oubreak in gay and bisexual men in Europe is growingKeith Alcorn | 7 years ago New cases of hepatitis A cases have soared in Western Europe over the past six months as a result o......MORE |
Hepatitis A outbreak in gay and bisexual men in Europe is growingKeith Alcorn | 7 years ago New cases of hepatitis A cases have soared in Western Europe over the past six months as a result o......MORE |
San Francisco task force releases first hepatitis C estimatesLiz Highleyman | 7 years ago End Hep C SF, a consortium of public health workers, medical providers, advocates and people living......MORE |
Study identifies serious gaps in treatment and care of HIV-positive adolescents in sub-Saharan AfricaMichael Carter | 7 years ago Healthcare providers in sub-Saharan Africa are struggling to provide services for HIV-positive adol......MORE |
Why are women lost from HIV care during pregnancy? Malawi study shows social support and counselling are criticalKeith Alcorn | 7 years ago Lack of social support after diagnosis and inadequate counselling about HIV treatment and HIV disc......MORE |
HIV drug resistance becoming more common in Zambian infantsKeith Alcorn | 7 years ago The proportion of infants with HIV who had drug resistance at the time of HIV diagnosis almost doub......MORE |
New pangenotypic hepatitis C drug combinations recommended for approval in the European UnionKeith Alcorn | 7 years ago Two new pangenotypic direct-acting antiviral combinations have received positive opinions from the ......MORE |
Many Western European countries close to achieving UNAIDS 90-90-90 targetsMichael Carter | 7 years ago Countries in Western and Southern Europe are well on their way to meeting the UNAIDS 90-90-90 targe......MORE |
HIV has a similar impact to diabetes on heart disease riskKeith Alcorn | 7 years ago Living with HIV carries the same lifetime risk of cardiovascular disease as having diabetes, even a......MORE |
Researchers say rule out depression, anxiety, unemployment and other stresses before blaming cognitive impairment for everyday difficultiesMichael Carter | 7 years ago One in five people living with HIV in a European study reported a decline in everyday functioning a......MORE |
Risk score can identify which HIV-positive people with controlled viral load are at greatest risk of neurocognitive declineMichael Carter | 7 years ago Four factors are associated with neurocognitive decline in people living with HIV with an undetecta......MORE |
Experts question Cochrane review of hepatitis C treatmentKeith Alcorn | 7 years ago A systematic review of hepatitis C direct-acting antiviral studies published by the Cochrane Collab......MORE |
HIV drug resistance testing not a priority for resource-limited settings, trial findsKeith Alcorn | 7 years ago Resistance testing is unlikely to improve the effectiveness of second-line HIV treatment in resourc......MORE |
Fractures occur at an earlier age among men with HIVMichael Carter | 7 years ago The incidence of fractures begins to rise a full decade earlier in HIV-positive men compared to the......MORE |
High prevalence of tobacco use among HIV-positive individuals in low- and middle-income countriesMichael Carter | 7 years ago There is a high prevalence of tobacco use among HIV-positive adults in low- and middle-income count......MORE |
Taking PrEP has a profound impact on gay men’s sexual health and wellbeingRoger Pebody | 7 years ago Men who have sex with men (MSM) in Seattle who had recently begun to take pre-exposure prophylaxis ......MORE |
Swiss Grindr survey finds 50% want to use PrEP in the next six monthsGus Cairns | 7 years ago A survey of Swiss gay men and men who have sex with men recruited through the Grindr networking app......MORE |
Point-of-care CD4 counts improve linkage to HIV care in KenyaKeith Alcorn | 7 years ago Carrying out a point-of-care CD4 count immediately after a person was diagnosed with HIV by home-ba......MORE |
MSM, especially if HIV-positive, have an increased risk of meningococcal disease, according to US researchMichael Carter | 7 years ago Men who have sex with men (MSM) have an increased risk of meningococcal disease, investigators from......MORE |
Belgium, Portugal and Brazil will provide PrEP through their health services; Morocco announces a PrEP studyGus Cairns | 7 years ago In the last two weeks, several countries have announced that they will soon launch pre-exposure pro......MORE |
Six-question risk score can identify HIV-positive gay men needing testing for acute hepatitis CRoger Pebody | 7 years ago Six questions can identify HIV-positive gay men who are at elevated risk of having acute (recent) h......MORE |
Young women in Zimbabwe in sexual relationships with older men have an especially high risk of infection with HIVMichael Carter | 7 years ago Young women in Zimbabwe have an especially high risk of infection with HIV if they have a sexual pa......MORE |
HIV treatment targets for people who inject drugs will be missed without focus on rights, privacy and prisonsSusie McLean | 7 years ago Reaching ambitious HIV treatment targets for people who use drugs requires efforts to protect priv......MORE |
High frequency of recurrent high-grade pre-cancerous anal lesions in HIV-positive MSMMichael Carter | 7 years ago A high proportion of HIV-positive men who have sex with men (MSM) successfully treated for high-gra......MORE |
Agreements with cash incentives boost patient adherence to HIV therapy and rates of viral suppressionMichael Carter | 7 years ago Patients who enter into a contract with their HIV healthcare provider to receive cash incentives in......MORE |
Heroin combined with fentanyl is driving overdose crisis in USLiz Highleyman | 7 years ago New sources of heroin and increasing adulteration with fentanyl and other stronger analogues are co......MORE |
Injecting drug use increases worldwide, but no increases in needle and syringe programmesSusie McLean | 7 years ago Despite reports of expanding rates of injecting drug use in a new list of countries around the worl......MORE |
Indonesian buyers club helps people obtain generic hepatitis C treatmentLiz Highleyman | 7 years ago A community-led buyers club in Indonesia has helped more than 100 people get generic direct-acting ......MORE |
Pet care can connect people to health and harm reduction servicesLiz Highleyman | 7 years ago Providing free veterinary care can be a good way to bring homeless and marginally housed people int......MORE |
Use of psychedelic drugs may reduce the risk of suicide in female sex workersLiz Highleyman | 7 years ago Women sex workers who used psychedelic drugs such as LSD were less likely to think about or attempt......MORE |
People with HIV have impaired respiratory health, even when viral load is undetectableMichael Carter | 7 years ago HIV-positive people have impaired respiratory health, even when they have viral suppression with an......MORE |
Canadian Minister of Health opens International Harm Reduction conference amid controversy over overdose deathsSusie Mclean | 7 years ago The 25th International Harm Reduction Conference (HR17) in Montréal, Canada, kicked off with a dra......MORE |
People who use drugs may use cannabis and drug cocktails as a form of harm reductionLiz Highleyman | 7 years ago People who use drugs have come up with innovative strategies that help them reduce harm, including ......MORE |
Many physicians are wary of providing HIV PrEP for young peopleLiz Highleyman | 7 years ago Only about a third of family practice and paediatric providers said they would be likely to prescri......MORE |
Hepatitis C virus reinfection is uncommon after being cured with DAAsLiz Highleyman | 7 years ago Most people on opiate substitution therapy were successfully treated for hepatitis C with an interf......MORE |
Overamping is a common problem among people who use stimulantsLiz Highleyman | 7 years ago Overdosing on stimulants such as methamphetamine – known as 'overamping' – is an under-recognis......MORE |
Combining drug addiction treatment and perinatal HIV prevention leads to good outcomes in KenyaLiz Highleyman | 7 years ago An integrated programme offering medication-assisted drug addiction treatment and services aimed at......MORE |
Hydromorphone works as well as heroin-assisted drug addiction treatmentLiz Highleyman | 7 years ago Hydromorphone was as effective as pharmaceutical heroin for opioid addiction treatment, but it was ......MORE |
Drug checking reveals high levels of fentanyl contamination in Vancouver street drugsLiz Highleyman | 7 years ago A pilot project to check the purity of drugs at Vancouver's Insite safe injection facility found th......MORE |
AA amyloidosis is an unrecognised problem among people who inject drugsLiz Highleyman | 7 years ago AA amyloidosis, a condition resulting from skin and soft tissue infections that can lead to kidney ......MORE |
Life expectancy now near-normal in people with CD4 counts over 350 a year after starting therapyGus Cairns | 7 years ago A large study of 88,504 people with HIV on antiretroviral therapy (ART), published in the Lancet jo......MORE |
Protease inhibitor drug suppresses HIV in semen more slowly than drugs from other classesGus Cairns | 7 years ago Protease inhibitors may not be the best class of drug for people newly diagnosed with HIV to start ......MORE |
MDR-TB numbers could keep growing despite improved treatmentKeith Alcorn | 7 years ago Up to one-in-three tuberculosis cases in Russia could be multidrug resistant by 2040, and one-in-ei......MORE |
MDR TB numbers could keep growing despite improved treatmentKeith Alcorn | 7 years ago Up to one in three tuberculosis cases in Russia could be multi-drug resistant by 2040, and one in e......MORE |
Switching from efavirenz to lopinavir/ritonavir has no meaningful impact on neurological function, says UK studyMichael Carter | 7 years ago Switching from efavirenz does not significantly improve the neurological function of patients takin......MORE |
Undocumented migrants more likely to be lost to follow-up and have poor virological outcomes after starting ART, Milan study confirmsMichael Carter | 7 years ago Undocumented migrants living with HIV have especially poor rates of retention in care and virologic......MORE |
Besifovir and tenofovir exalidex look promising as new hepatitis B drugsLiz Highleyman | 7 years ago Two investigational nucleotide analogue antivirals were shown to be active against hepatitis B viru......MORE |
Naloxone is a heath intervention that can’t be effectively provided without the knowledge and social connections of people who inject drugsRoger Pebody | 7 years ago Programmes to provide naloxone, a drug that reverses the effects of opiate overdose, are successful......MORE |
Fear of stigma is prompting young South Africans to seek early HIV treatmentKeith Alcorn | 7 years ago Young South Africans are strongly motivated to seek HIV testing and treatment by a desire to mainta......MORE |
Increased screening for syphilis boosts detection of early latent infections among Australian gay menMichael Carter | 7 years ago Increased syphilis testing among gay men increased detection of early latent infections and was acc......MORE |
Avoiding false positives: rapid HIV tests vary in their accuracy, so need to be used in combinationRoger Pebody | 7 years ago An evaluation of eight widely used rapid diagnostic tests used in a variety of African countries by......MORE |
Triple combination cures most hepatitis C patients with prior DAA treatment failureLiz Highleyman | 7 years ago Almost all people with genotype 1 hepatitis C who were previously unsuccessfully treated with a cou......MORE |
Early ART highly acceptable and achieves excellent rates of viral suppression among young South African womenMichael Carter | 7 years ago Early antiretroviral therapy (ART) is highly acceptable to the majority of young women with HIV in ......MORE |
EASL releases updated hepatitis B guidelines at International Liver CongressLiz Highleyman | 7 years ago The European Association for the Study of the Liver (EASL) presented revised clinical practice guid......MORE |
Switching to TAF for hepatitis B improves kidney function and bone lossLiz Highleyman | 7 years ago People with hepatitis B who switched from the old tenofovir disoproxil fumarate (TDF) to the new te......MORE |
A quarter of people with second-line ART treatment failure in Kenya have exhausted current treatment optionsMichael Carter | 7 years ago Affordable third-line antiretrovirals are urgently needed in resource-limited settings, according t......MORE |
A quarter of people taking antiretroviral therapy in Kenya have exhausted current treatment optionsMichael Carter | 7 years ago Affordable third-line antiretrovirals are urgently needed in resource-limited settings, according t......MORE |
Generic hepatitis C drugs continue to produce high cure ratesKeith Alcorn | 7 years ago Treatment with generic versions of direct-acting antiviral drugs continues to produce similar cure ......MORE |
Switching from Atripla to generic-containing regimens can produce large cost savingsMichael Carter | 7 years ago Switching from branded Atripla to regimens that include at least one generic drug formulation can a......MORE |
AbbVie combination cures 97% of genotype 3 hepatitis CKeith Alcorn | 7 years ago AbbVie's pangenotypic direct-acting antiviral combination of two drugs cured 97% of people with ear......MORE |
AbbVie combination cures 95% of genotype 3 hepatitis CKeith Alcorn | 7 years ago AbbVie's pangenotypic direct-acting antiviral combination of two drugs cured 95% of people with ear......MORE |
New AbbVie hepatitis C combination cures 99% of people with cirrhosisKeith Alcorn | 7 years ago A new pangenotypic direct-acting antiviral combination developed by AbbVie is highly effective in ......MORE |
Direct-acting antivirals for hepatitis C not linked to higher liver cancer risk in most studiesLiz Highleyman | 7 years ago People with hepatitis C who take treatment with direct-acting antivirals (DAAs) do not appear to ha......MORE |
European HCV treatment access survey shows big variations in eligibilityKeith Alcorn | 7 years ago England, Malta, Slovakia, Hungary and Croatia have the tightest restrictions on who can receive dir......MORE |
Curing hepatitis C reduces cardiovascular riskKeith Alcorn | 7 years ago Curing hepatitis C reduces the risk of cardiovascular events in people with compensated cirrhosis,......MORE |
Monitoring of progress towards 90-90-90 blighted by poor quality reportingMichael Carter | 7 years ago Only six countries, representing just 2% of the global HIV burden, have high quality data reporting......MORE |
Hepatitis C treatment can be provided successfully at syringe programme sitesLiz Highleyman | 7 years ago Administering direct-acting antiviral therapy for people who inject drugs at a syringe exchange sit......MORE |
Study shows that HIV-positive nursing mothers in London can struggle to obtain and afford formula milkMichael Carter | 7 years ago Many HIV-positive nursing mothers in London are struggling to meet the financial costs of formula f......MORE |
Black HIV-positive MSM in US still have lower rates of ART useMichael Carter | 7 years ago The proportion of newly diagnosed HIV-positive men who have sex with men (MSM) in the United States......MORE |
Homeless US military veterans have high rates of HIV, HCV and HBVMichael Carter | 7 years ago Homeless veterans in the United States have a significantly higher prevalence of infection with HIV......MORE |
Behaviour change interventions in HIV prevention: is there still a place for them?Gus Cairns | 7 years ago A meta-analysis of studies of brief interventions to reduce HIV risk behaviour in HIV-negative gay ......MORE |
London data show that hepatitis C is passed on during anal sex without a condomRoger Pebody | 7 years ago Around one in five HIV-positive gay men who recently acquired hepatitis C report anal sex without a......MORE |
PrEP is approved in ScotlandGus Cairns | 7 years ago The Scottish Medicines Consortium (SMC) today announced that it had accepted tenofovir disoproxil/e......MORE |
Health system navigators didn't improve ART initiation or TB treatment completion rates among people newly diagnosed with HIV in DurbanMichael Carter | 7 years ago An intervention using health system navigators, phone support and text message reminders did not im......MORE |
Suicide accounts for 2% of deaths in people with HIV, twice the rate of the general populationRoger Pebody | 7 years ago Men living with HIV have an elevated rate of suicide, particularly in the first year after diagnosi......MORE |
The large fall in HIV diagnoses in London gay men is real and thanks to combination prevention, not just PrEPRoger Pebody | 7 years ago The number of new HIV diagnoses in gay men attending five key London clinics fell substantially dur......MORE |
Tracking down patients lost to HIV care: home visits need to be carefully targetedKeith Alcorn | 7 years ago Efforts to track patients lost to care are likely to produce very little return on the money and ti......MORE |
PrEP should be given to all breastfed babies, researchers sayGus Cairns | 7 years ago An international group of researchers involved in the ANRS 12174 randomised controlled trial of pre......MORE |
Poppers linked to increased risk of some cancers in older MSM without HIVKeith Alcorn | 7 years ago Daily or weekly use of poppers over a number of years is associated with a substantial increase in ......MORE |
Poppers linked to increased risk of some cancers in older men who have sex with men without HIVKeith Alcorn | 7 years ago Daily or weekly use of poppers over a number of years is associated with a substantial increase in ......MORE |
Co-infection with HCV increases cancer risk for people with HIVMichael Carter | 7 years ago People with HIV and hepatitis C virus (HCV) co-infection have an increased risk of non-AIDS-definin......MORE |
Black gay men still at higher risk of HIV in the UKRoger Pebody | 7 years ago Gay and bisexual men of black ethnicity are disproportionately likely to be living with diagnosed H......MORE |
Warning of hepatitis A outbreak among men who have sex with men in EuropeKeith Alcorn | 7 years ago An outbreak of hepatitis A in Europe has affected 287 people in at least 13 countries, with large ......MORE |
Investigating late HIV diagnoses as serious incidents may spur change across the health systemRoger Pebody | 7 years ago Investigating cases of very late HIV diagnosis through the NHS’ serious incident reporting proces......MORE |
Nurse-led intervention improves adherence to ART and is cost-effectiveMichael Carter | 7 years ago An antiretroviral therapy (ART) adherence support study conducted in the Netherlands has been haile......MORE |
Bone density improves in people who switch from tenofovir DF to tenofovir alafenamideLiz Highleyman | 7 years ago After three years, tenofovir alafenamide (TAF) for first-line HIV treatment was better at suppressi......MORE |
Scotland reports its lowest number of HIV diagnoses since 2003Gus Cairns | 7 years ago A report released on Tuesday by Health Protection Scotland shows that last year saw the lowest numb......MORE |
Two-thirds of people with HIV/HCV co-infection in Southeast Asia in need of HCV therapyMichael Carter | 7 years ago Almost two-thirds of people with HIV/hepatitis C virus (HCV) co-infection in Asia are in need of HC......MORE |
Research helps explain how vedolizumab antibody therapy leads to sustained viral remissionLiz Highleyman | 7 years ago HIV and its monkey cousin SIV can carry the alpha-4 beta-7 integrin receptor in their outer envelop......MORE |
Fewer clinic visits improve retention in HIV care in ZambiaKeith Alcorn | 7 years ago People with HIV who attended their clinic once every six months were much less likely to miss their......MORE |
Harm reduction should address the specific needs of couples who inject drugsRoger Pebody | 7 years ago The sharing of drug injecting equipment most often occurs between sexual partners, but the ways in ......MORE |
Vietnam will struggle to meet 90-90-90 targets without addressing barriers to HIV care for men who have sex with menRoger Pebody | 7 years ago Men who have sex with men in Vietnam risk being left behind as the country strives to achieve UNAID......MORE |
Finding men with HIV – and keeping them in treatmentKeith Alcorn | 7 years ago Specialised services to attract men to HIV testing and treatment may need to adopt several differen......MORE |
Linkage to HIV care still challenging for young men, Botswana study findsKeith Alcorn | 7 years ago Almost one in five people newly diagnosed with HIV in a study employing active methods to link peop......MORE |
Several new candidates in HIV drug pipeline discussed at conferenceLiz Highleyman | 7 years ago This year's Conference on Retroviruses and Opportunistic Infections (CROI 2017), held last month i......MORE |
Studies look at brain and cognitive changes in people with HIV as they ageLiz Highleyman | 7 years ago People with HIV often show persistent signs of cognitive impairment and abnormalities in brain stru......MORE |
Early adherence to ART key to long-term virological outcomesMichael Carter | 7 years ago Adherence to antiretroviral therapy (ART) in the first few months after starting treatment is cruci......MORE |
'Test and treat' study shows second phase is finding more people with HIV and getting them onto treatmentKeith Alcorn | 7 years ago After a second wave of intensive household testing, a large study of the 'test and treat' strategy ......MORE |
Glecaprevir/pibrentasvir for hepatitis C can be safely administered with common antiretroviralsLiz Highleyman | 7 years ago AbbVie's investigational glecaprevir/pibrentasvir treatment for hepatitis C is not expected to inte......MORE |
Dolutegravir monotherapy fails to maintain HIV viral suppression, but dolutegravir + lamivudine looks goodLiz Highleyman | 7 years ago Dolutegravir used alone without other antiretrovirals was unable to keep viral load suppressed in s......MORE |
DAA therapy cures most people with HIV/HCV co-infection with decompensated cirrhosis or liver transplantsLiz Highleyman | 7 years ago People with HIV/hepatitis C virus (HCV) co-infection with liver cirrhosis or liver failure, and th......MORE |
D:A:D study – long-term use of darunavir/ritonavir modestly increases the risk of cardiovascular diseaseMichael Carter | 7 years ago Long-term use of the protease inhibitor darunavir/ritonavir modestly increases the risk of cardiova......MORE |
Simple risk score can identify gay men who may have acute HIV infectionRoger Pebody | 7 years ago Seven simple questions about symptoms and risk factors identified three-quarters of gay men in Amst......MORE |
Researchers report case of bone marrow transplant patient off ART for 288 days without HIV reboundLiz Highleyman | 7 years ago An HIV-positive bone marrow transplant recipient at the Mayo Clinic experienced prolonged viral rem......MORE |
New HIV capsid inhibitors show high potency and prolonged activity in early studiesLiz Highleyman | 7 years ago A novel type of antiretroviral drug that interferes with the assembly and disassembly of the HIV ca......MORE |
HIV’s milder cousin may be less mild than previously thoughtGus Cairns | 7 years ago HIV-2’s virulence may have been underestimated and although progression to AIDS and death in HI......MORE |
Integrase inhibitors may increase risk of IRIS in late presenters for HIV treatmentKeith Alcorn | 7 years ago HIV integrase inhibitors such as dolutegravir and raltegravir may increase the risk of immune recon......MORE |
What is safe sex now? Does it include undetectable viral load and PrEP?Roger Pebody | 7 years ago Treatment as prevention and PrEP provide new ways to safely avoid HIV, but this poses challenges to......MORE |
Are people with HIV and HCV co-infection who are cured of hepatitis C with DAAs at increased risk for liver cancer?Liz Highleyman | 7 years ago People with HIV and hepatitis C virus (HCV) co-infection who are successfully treated for hepatitis......MORE |
Bacterial vaginosis does not affect efficacy of oral PrEP in womenGus Cairns | 7 years ago Research presented at the Conference on Retroviruses and Opportunistic Infections (CROI 2017) found......MORE |
STI rates in PrEP users very high, but evidence that PrEP increases them is inconclusiveGus Cairns | 7 years ago A study of PrEP users presented at the Conference on Retroviruses and Opportunistic Infections (CRO......MORE |
Monoclonal antibodies show promise for HIV-positive people with limited treatment optionsLiz Highleyman | 7 years ago A pair of long-acting monoclonal antibodies that prevent HIV from entering human cells – ibalizum......MORE |
No evidence of risk compensation after circumcision in three African cohortsRoger Pebody | 7 years ago Three large studies in South Africa, Zimbabwe and Kenya have found no evidence that men who have be......MORE |
Accelerated linkage to HIV care improves retention in care by a thirdCarole Leach-Lemens | 7 years ago Close to 60% of adults benefiting from point-of-care CD4 cell count testing at HIV testing sites, a......MORE |
Better depression care could improve outcomes for HIV treatment programmesRoger Pebody | 7 years ago Improved management of depression and other mental health disorders has the potential to improve th......MORE |
Peer navigators improve linkage to HIV care and retention in care in South African studyCarole Leach-Lemens | 7 years ago Adults recently diagnosed with HIV getting help from peers to address personal barriers to care tog......MORE |
Prednisone reduces the risk of developing TB-IRIS after starting antiretroviral treatmentKeith Alcorn | 7 years ago Prednisone reduces the risk of an immune restoration inflammatory syndrome (IRIS) in people with HI......MORE |
Will there be a new wave of HIV in people who inject drugs in the US?Gus Cairns | 7 years ago Ever since there was an outbreak of HIV among white, largely rural heroin users in Indiana in 2015,......MORE |
Will there be a new wave of HIV in injecting drug users in the US?Gus Cairns | 7 years ago Ever since there was an outbreak of HIV among white, largely rural heroin users in Indiana in 2015,......MORE |
New NNRTI doravirine shows good efficacy in phase 3 studyLiz Highleyman | 7 years ago Doravirine, an investigational next-generation non-nucleoside reverse transcriptase inhibitor (NNRT......MORE |
Time spent by US HIV patients in care with a transmissible viral load has fallen by three-quarters since 2000Gus Cairns | 7 years ago A study by the US Centers for the Disease Control (CDC) presented at the recent Conference on Retro......MORE |
Time spent by people in HIV care in US with a transmissible viral load has fallen by three-quarters since 2000Gus Cairns | 7 years ago A study by the US Centers for Disease Control and Prevention (CDC) presented at the recent Conferen......MORE |
One in five ‘heterosexual’ men in the UK caught their HIV from another manGus Cairns | 7 years ago A genetic analysis of a large database of UK people with HIV in care shows that 18% of men with HIV......MORE |
When science, community and political will come together, we can end the epidemic, says New York commissionerRoger Pebody | 7 years ago New York City’s strategy to end the AIDS epidemic is firmly rooted in science, was developed in c......MORE |
Spanish vaccine induces viral control off ART in nearly 40% of recipientsGus Cairns | 7 years ago A so-called ‘HIV Conserv’ vaccine has, for the first time, produced significant prolonged viral......MORE |
New hepatitis C infections among HIV-positive gay men drop by half after direct-acting antiviral roll-out in NetherlandsLiz Highleyman | 7 years ago A little more than a year after the Netherlands instituted a policy allowing unrestricted access to......MORE |
Three-drug regimen beats XDR-TB in first trialKeith Alcorn | 7 years ago A regimen of three oral drugs given for six months was enough to clear XDR-TB in 29 of the first 31......MORE |
How should HIV self-testing services be provided?Roger Pebody | 7 years ago Chairing a session on HIV self-testing at the 2017 Conference on Retroviruses and Opportunistic In......MORE |
Stopping smoking cuts the risk of some cancers quickly in people with HIVKeith Alcorn | 7 years ago Smoking probably contributes far more to the risk of cardiovascular disease in people with HIV than......MORE |
Unique case of PrEP failure without drug resistance reported from AmsterdamGus Cairns | 7 years ago HIV pre-exposure prophylaxis (PrEP) appears to be nearly 100% effective if taken consistently so th......MORE |
New HIV infections fall in the US, but demographic and geographic disparities persistLiz Highleyman | 7 years ago The number of annual new HIV infections in the US fell by 18% overall since 2008, offering evidence......MORE |
Isoniazid preventive treatment reduces the risk of death by 37% in people living with HIVKeith Alcorn | 7 years ago A six-month course of isoniazid preventive treatment (IPT) at the beginning of the Temprano trial r......MORE |
Treatment or watchful waiting for cervical abnormalities in women with HIV?Carole Leach-Lemens | 7 years ago Close monitoring of earlier-stage cervical abnormalities (CIN-2) may be preferable to treatment for......MORE |
Tenofovir/emtricitabine/efavirenz less likely to cause adverse birth outcomes than other regimens, Botswana study findsCarole Leach-Lemens | 7 years ago Infants exposed to an antiretroviral regimen of tenofovir, emtricitabine and efavirenz (Atripla) fr......MORE |
Tenofovir/FTC/efavirenz less likely to cause adverse birth outcomes than other regimens, Botswana study findsCarole Leach-Lemens | 7 years ago Infants exposed to an antiretroviral (ART) regimen of tenofovir, emtricitabine and efavirenz (TDF/F......MORE |
Experimental STI prophylaxis in PrEP users produces big drops in syphilis and chlamydia infections but not in gonorrhoeaGus Cairns | 7 years ago Use of the antibiotic doxycycline as on-demand post-exposure prophylaxis by men who have sex with m......MORE |
Changes in viral suppression over time reveal disparities in HIV care in the United StatesLiz Highleyman | 7 years ago Sustained viral suppression over the course of a year may be a better measure than the most recent ......MORE |
Dual antiretroviral regimen maintains durable HIV suppression after switchLiz Highleyman | 7 years ago People who switched from standard antiretroviral therapy to a two-drug regimen of dolutegravir (Tiv......MORE |
Infants treated within days of birth can clear HIV reservoir rapidlyKeith Alcorn | 7 years ago Viral load and viral DNA fall rapidly in infants who begin antiretroviral therapy within days of bi......MORE |
Treatment-as-prevention study sees substantial levels of transmitted drug resistance in participants, but no impact on treatmentGus Cairns | 7 years ago A study of the prevalence of transmitted drug resistance in participants in the ANRS 12249 trial of......MORE |
Point-of-care test improves infant HIV diagnosis rate, treatment starts and retention in careKeith Alcorn | 7 years ago Using a point-of-care test to diagnose HIV in infants significantly improved retention in care, spe......MORE |
Integrase inhibitor bictegravir matches dolutegravir for first-line HIV treatmentLiz Highleyman | 7 years ago Bictegravir, an investigational integrase inhibitor from Gilead Sciences, was highly potent, well t......MORE |
A benign circle: how a combination of factors has reduced HIV infections in one of the hardest-hit parts of AfricaGus Cairns | 7 years ago HIV incidence has started to tumble in one of the best-studied groups of people in Africa, the Conf......MORE |
Men from Latin America and central Europe now outnumber sub-Saharan Africans in HIV diagnoses in European migrantsGus Cairns | 7 years ago The latest figures from the European Centre for Disease Control (ECDC), presented at the recent HIV......MORE |
Across western Europe, migrants from all parts of the world start HIV treatment laterRoger Pebody | 7 years ago An analysis of over 150,000 people living with HIV in eleven western European countries shows that ......MORE |
Living with diagnosed HIV infection for a long time is associated with poor quality of lifeMichael Carter | 7 years ago Longer time living with diagnosed HIV infection is strongly associated with depression, anxiety and......MORE |
Sustained reductions in sexual risk behaviour following couples’ HIV testingRoger Pebody | 7 years ago A programme of couples’ HIV testing and counselling in Zambia appears to result in durable reduct......MORE |
Delays in linkage to care after HIV diagnosis pose the biggest barrier to treatment accessKeith Alcorn | 7 years ago Following individuals through the cascade of care, from HIV diagnosis to treatment and undetectable......MORE |
Women significantly more likely than men to have suboptimal adherence to HIV therapyMichael Carter | 7 years ago Women are more likely than men to have poor adherence to combination antiretroviral therapy (cART),......MORE |
Legalisation of sex work associated with lower prevalence of HIV in sex workersRoger Pebody | 7 years ago Countries that have legalised some aspects of sex work have fewer sex workers living with HIV than ......MORE |
High hepatitis C prevalence seen in Amsterdam PrEP study participantsGus Cairns | 7 years ago Researchers from the Dutch PrEP demonstration study, AmPrEP, have found an unexpectedly high rate o......MORE |
Recreational drug use very common among HIV-positive Londoners admitted for inpatient careMichael Carter | 7 years ago Recent recreational drug use is highly prevalent among HIV-positive people admitted to inpatient ca......MORE |
Recreational drug use very common among HIV-positive Londoners admitted for in-patient careMichael Carter | 7 years ago Recent recreational drug use is highly prevalent among HIV-positive people admitted to in-patient c......MORE |
Curing hepatitis C reduces the risk of diabetes & kidney failure in people with HIV/HCV co-infectionKeith Alcorn | 7 years ago Curing hepatitis C infection substantially reduces the risk of developing type 2 diabetes in people......MORE |
Hope overshadowed – the US PrEP SummitGus Cairns | 7 years ago The US National HIV PrEP Summit, which took place in early December in San Francisco, was one of th......MORE |
Liver cirrhosis and decompensation still on the rise among people with hepatitis CLiz Highleyman | 7 years ago Complications of advanced liver disease including cirrhosis and hepatic decompensation have risen o......MORE |
Two-thirds of HIV clinics in the UK don't think there's a current need for specialist services for older HIV-positive patientsMichael Carter | 7 years ago Two-thirds of HIV clinics in the UK do not think there is a current need for specialist care servic......MORE |
Is DAA treatment for hepatitis C reducing the need for liver transplants?Liz Highleyman | 7 years ago People successfully treated for hepatitis are less likely to need liver transplants and less likely......MORE |
No new HIV infections in Northern California Kaiser PrEP programme, but STI rates risingLiz Highleyman | 7 years ago No new HIV infections have been seen among nearly 1000 people who started Truvada for pre-exposure ......MORE |
Starting treatment quickly after diagnosis is not harmful for adolescents, Zimbabwe study findsKeith Alcorn | 7 years ago A lack of lengthy preparation before starting HIV treatment does not result in an increased risk of......MORE |
High prevalence of low testosterone among younger and middle-aged ART-treated men in FranceMichael Carter | 7 years ago Around one in six young and middle-aged HIV-positive men doing well on antiretroviral therapy (ART)......MORE |
Regular small incentives can improve adherence to ARTMichael Carter | 7 years ago The provision of regular low-value economic incentives can improve adherence to antiretroviral ther......MORE |
What are the key steps to effective delivery of PrEP care?Roger Pebody | 7 years ago Providing pre-exposure prophylaxis (PrEP) to people who need it entails at least nine key steps, wh......MORE |
Many older people living with HIV in the UK worried about poverty, loneliness and social careRoger Pebody | 7 years ago People over the age of 50 now represent one third of all people living with HIV, but the social car......MORE |
Vitamin D deficiency reduces statin potency, increases risk of muscle pain in people with HIVKeith Alcorn | 7 years ago People living with HIV who take statins are less likely to experience cholesterol reductions and mo......MORE |
Tenofovir alafenamide approved for hepatitis B in EuropeLiz Highleyman | 7 years ago The European Commission this week granted marketing authorisation for tenofovir alafenamide, to be ......MORE |
ART-treated patients in UK have an accurate understanding of their viral loadMichael Carter | 7 years ago The vast majority of antiretroviral (ART)-treated patients in the UK have an accurate knowledge of ......MORE |
People taking ART in the UK have an accurate understanding of their viral loadMichael Carter | 7 years ago The vast majority of people taking antiretroviral therapy (ART) in the UK have an accurate knowledg......MORE |
Implants and injectables: PrEP in the futureKeith Alcorn | 7 years ago Last month’s announcement that the Bill and Melinda Gates Foundation will give up to $140 million......MORE |
Risk of pregnancy loss among smokers much higher for women with HIVMichael Carter | 7 years ago Smoking “dramatically” increases the risk of pregnancy loss – miscarriage or stillbirth – i......MORE |
Risk score accurately predicts which pregnant and postpartum women would benefit most from PrEPMichael Carter | 7 years ago A risk score based on routine assessments carried out during antenatal care in resource-limited set......MORE |
Nearly two-thirds of European HIV cases are now in RussiaGus Cairns | 7 years ago The annual number of new cases of HIV increased by at least 8% in 2015 in the whole of the World He......MORE |
Scaling up adult male circumcision calculated to have HIV prevention benefits additional to those seen with 90-90-90 treatment targetMichael Carter | 7 years ago Scale-up of voluntary medical male circumcision (VMMC) in countries with a high HIV prevalence has ......MORE |
Viral load rebounds in a third of women who start HIV therapy during pregnancy or postpartum, South African study showsMichael Carter | 7 years ago Approximately one-third of HIV-positive women who attain viral suppression after starting antiretro......MORE |
Viral load testing capacity still weak in sub-Saharan Africa, 7-country study findsKeith Alcorn | 7 years ago Viral load testing capacity is still weak in some of the countries with the highest burden of HIV i......MORE |
People with HIV/HCV co-infection at increased risk of kidney disease and bone disordersMichael Carter | 7 years ago Hepatitis C virus (HCV) infection in people with HIV co-infection is associated with an increased r......MORE |
Virologic failure detected in a quarter of ART-treated children in TanzaniaMichael Carter | 7 years ago A quarter of children and adolescents in Tanzania taking antiretroviral therapy (ART) have major re......MORE |
The UK’s largest sexual health clinic saw a 40 percent drop in new HIV infections this yearGus Cairns | 7 years ago The clinic at 56 Dean Street in Soho, central London, the largest sexual health clinic in the UK, s......MORE |
In the era of universal treatment, what are HIV clinical guidelines for?Gus Cairns | 7 years ago The purpose and structure of clinical HIV guidelines may have to change radically now that universa......MORE |
African Americans taking ART have high incidence of illness associated with risk of cardiovascular diseaseMichael Carter | 7 years ago Black HIV-positive men and women receiving antiretroviral therapy (ART) have especially high rates ......MORE |
Co-morbidities are common and rising among people with HIV in the USLiz Highleyman | 7 years ago People living with HIV are increasingly experiencing a range of non-AIDS-related comorbidities as t......MORE |
High prevalence of resistance to zidovudine among people in sub-Saharan Africa experiencing virological failure with tenofovir-containing ARTMichael Carter | 7 years ago A significant proportion of people with virological failure after treatment with tenofovir-containi......MORE |
Migration and age differences between male and female partners fuelling the HIV epidemic in South AfricaRoger Pebody | 7 years ago Analyses from two large household surveys in KwaZulu-Natal, South Africa shed new light on the dyna......MORE |
Multiple motivations for ‘transactional sex’ need to be taken into account when planning interventions for African womenRoger Pebody | 7 years ago Many HIV prevention strategies identify ‘transactional sex’ as a practice that contributes to y......MORE |
Malawi, Zambia and Zimbabwe making strong progress towards the 90-90-90 goalsKeith Alcorn | 7 years ago Malawi, Zambia and Zimbabwe are making strong progress towards achieving the treatment and viral su......MORE |
Almost half of MSM with HIV/HCV co-infection have HCV in their rectal fluidMichael Carter | 7 years ago Almost half of HIV-positive men who have sex with men (MSM) who have co-infection with hepatitis C ......MORE |
Sofosbuvir-based therapy achieves excellent SVR12 rates among people who inject drugs in the UkraineMichael Carter | 7 years ago People who inject drugs (PWID) can have an excellent response to sofosbuvir-based therapy for hepat......MORE |
Sofosbuvir-based therapy achieves excellent SVR12 rates among people who inject drugs in UkraineMichael Carter | 7 years ago People who inject drugs (PWID) can have an excellent response to sofosbuvir-based therapy for hepat......MORE |
United States: Syringe service use up, but a third of people who inject drugs still share needlesLiz Highleyman | 7 years ago Use of syringe exchange and distribution services has increased substantially over the past decade ......MORE |
Electronic monitoring of antiretroviral adherence in "real time" boosts pill taking and need for intensive adherence supportMichael Carter | 7 years ago Electronic monitoring of antiretroviral adherence in “real time” significantly increases the pr......MORE |
Electronic monitoring of antiretroviral adherence in "real-time" boosts pill taking and need for intensive adherence supportMichael Carter | 7 years ago Electronic monitoring of antiretroviral adherence in “real time” significantly increases the pr......MORE |
Hepatitis C virus infection is rising among gay and bisexual men in San DiegoLiz Highleyman | 7 years ago The prevalence of hepatitis C virus (HCV) infection among HIV-positive men who have sex with men in......MORE |
NHS England announces major new PrEP trial for 2017Gus Cairns | 7 years ago NHS England, in collaboration with Public Health England, has announced in a press release today th......MORE |
Survey finds good knowledge of PrEP in Europe and a considerable amount of unsupported informal PrEP useGus Cairns | 7 years ago A large survey of knowledge and use of pre-exposure prophylaxis (PrEP) in Europe released its preli......MORE |
There may be fewer people living with undiagnosed HIV in the UK than previously thoughtRoger Pebody | 7 years ago Public Health England’s estimate of the number of people who have HIV without being aware of it h......MORE |
CDC releases new data on HIV diagnosis and prevalence in the United StatesLiz Highleyman | 7 years ago In advance of World AIDS Day the US Centers for Disease Control and Prevention (CDC) released its l......MORE |
Ending the HIV epidemic faces daunting barriers, former WHO HIV chief warnsGus Cairns | 7 years ago The difficulty of bringing the HIV epidemic “down to zero” should not be underestimated, Kevin ......MORE |
World Health Organization urges scale-up of HIV self-testingRoger Pebody | 7 years ago HIV self-testing (sometimes called ‘home testing’) should be offered as an additional approach ......MORE |
Health agencies should challenge the idea that most gay men use drugsRoger Pebody | 7 years ago Drug use generally and chemsex more specifically are perceived to be common and normalised behaviou......MORE |
Sofosbuvir/ledipasvir is effective for people with HIV/HCV co-infection in real-world clinical practiceLiz Highleyman | 7 years ago The sofosbuvir/ledipasvir (Harvoni) co-formulation used in real-world clinical practice produced go......MORE |
Sofosbuvir/ledipasvir is effective for HIV/HCV co-infected people in real-world clinical practiceLiz Highleyman | 7 years ago The sofosbuvir/ledipasvir (Harvoni) coformulation used in real-world clinical practice produced goo......MORE |
Grazoprevir triple regimen demonstrates high cure rates, even for hard-to-treat peopleLiz Highleyman | 7 years ago A new three-drug co-formulation containing Merck's grazoprevir plus the investigational agents MK-3......MORE |
People with HIV/HCV co-infection see good cure rates in real-world practice in MadridLiz Highleyman | 7 years ago More than 90% of HIV-positive people treated with direct-acting antivirals for hepatitis C – incl......MORE |
Chemsex and slamming “suffused with romantic, emotional and communal attachments”Roger Pebody | 7 years ago While gay men’s use of drugs in sexual contexts is often portrayed as deviant, extreme and unconn......MORE |
8-week triple DAA combo cures most people with genotype 1-6 hepatitis CLiz Highleyman | 7 years ago A three-drug regimen of sofosbuvir, velpatasvir and voxilaprevir taken for 8 weeks demonstrated an ......MORE |
Birth cohort screening and linkage to care for HCV treatment still weak in United StatesKeith Alcorn | 7 years ago Grave weaknesses in hepatitis C screening and linkage to care are still widespread in the United St......MORE |
AbbVie pangenotypic combination cures 98% or above across genotypesKeith Alcorn | 7 years ago AbbVie’s combination of glecaprevir and pibrentasvir cured at least 98% of people with hepatitis ......MORE |
AbbVie pangenotypic combination cures almost all hard-to-treat people with HCV genotype 3Keith Alcorn | 7 years ago AbbVie’s pangenotypic combination of glecaprevir and pibrentasvir cured almost all of the hardest......MORE |
US Veterans Affairs and Australia show potential for rapid elimination of hepatitis CKeith Alcorn | 7 years ago If sufficient money is available to pay for direct-acting antivirals (DAAs), the US Veterans Affair......MORE |
Tenofovir alafenamide approved for hepatitis B, works well with less effect on bonesLiz Highleyman | 7 years ago Tenofovir alafenamide (TAF), a new lower-dose pro-drug, matches the older tenofovir disoproxil fuma......MORE |
Self-sampling for HIV testing popular with gay men who have not recently tested, but less uptake by African peopleRoger Pebody | 7 years ago Three quarters of those using England’s free self-sampling service are men who have sex with men,......MORE |
Long term decline in consistent condom use among Australian gay menRoger Pebody | 7 years ago Data from the last ten years of the Australian Gay Community Periodic Surveys shows a steady declin......MORE |
Grazoprevir/elbasvir + sofosbuvir highly effective for hard-to-treat genotype 3 hepatitis C patientsLiz Highleyman | 7 years ago A triple regimen of grazoprevir/elbasvir (Zepatier) plus sofosbuvir (Sovaldi) without ribavirin cur......MORE |
Liver cancer risk reduced after hepatitis C treatment, but vigilance needed for aggressive cancers in months after treatmentKeith Alcorn | 7 years ago People who are cured of hepatitis C after a course of direct-acting antiviral treatment do not hav......MORE |
Real-world responses to HCV treatment among US veterans match best clinical trial resultsKeith Alcorn | 7 years ago Direct-acting antiviral treatment is curing people of hepatitis C infection in clinics at similar r......MORE |
The ‘long tail’ problem: injected-PrEP trial will be extended due to persistence of drug in companion studyGus Cairns | 7 years ago A study presented at last month’s HIV Research for Prevention (HIVR4P) conference in Chicago show......MORE |
The ‘long tail’ problem: forthcoming injected-PrEP efficacy trial delayed due to persistence of drug in some volunteersGus Cairns | 7 years ago A study presented at last month’s HIV Research for Prevention (HIVR4P) conference in Chicago show......MORE |
NHS England loses appeal – it must consider providing PrEPRoger Pebody | 7 years ago At the Court of Appeal in London this morning, three judges confirmed that NHS England is responsib......MORE |
Tenofovir alafenamide works well and improves kidney and bone markers in older people living with HIVLiz Highleyman | 7 years ago A co-formulation of tenofovir alafenamide (TAF) plus emtricitabine, used with a third antiretrovir......MORE |
Omega-3 fatty acids may reduce triglycerides and improve inflammation in people with HIVLiz Highleyman | 7 years ago Long-term use of omega-3 fatty acid supplements was associated with reduced levels of triglycerides......MORE |
Smoking more harmful than HIV for people taking effective treatment, US study suggestsKeith Alcorn | 7 years ago Smoking has the potential to shorten the life of a person taking HIV treatment by an average of six......MORE |
Dolutegravir regimen highly effective in clinical trial for womenLiz Highleyman | 8 years ago A once-daily regimen containing the potent HIV integrase inhibitor dolutegravir worked better than......MORE |
Ibalizumab monoclonal antibody looks promising for people with drug-resistant HIVLiz Highleyman | 8 years ago Ibalizumab, an experimental monoclonal antibody with a unique mechanism of action, demonstrated goo......MORE |
Men with HIV and men on PrEP in Boston see large increase in sexually transmitted infectionsLiz Highleyman | 8 years ago Rates of gonorrhoea, syphilis and chlamydia have risen steeply at Fenway Health in Boston since 201......MORE |
Four days on, three days off HIV treatment controls viral load in French pilot studyKeith Alcorn | 8 years ago An experimental `four days on, three days off` antiretroviral regimen kept viral load fully suppre......MORE |
Do people living with HIV who have an undetectable viral load need to wear condoms?Liz Highleyman | 8 years ago In the face of extensive research showing that people living with HIV who are on antiretroviral the......MORE |
Electronic health records can help select candidates for HIV PrEPLiz Highleyman | 8 years ago A machine learning algorithm used to analyse electronic health records (EHRs) identified high-risk ......MORE |
Darunavir/ritonavir & lamivudine matches triple-drug therapyKeith Alcorn | 8 years ago Simplifying antiretroviral therapy to a two-drug combination of lamivudine plus the protease inhibi......MORE |
Only a small proportion of gay men with HIV receive anal cancer screeningLiz Highleyman | 8 years ago In the absence of national screening guidelines, only 11% of HIV-positive gay and bisexual men in t......MORE |
New long-acting fusion inhibitor albuvirtide plus boosted protease inibitor matches standard triple-drug therapyKeith Alcorn | 8 years ago A new fusion inhibitor, albuvirtide, under development in China, combined with a boosted protease i......MORE |
Generic hepatitis C drugs purchased online achieve high cure ratesKeith Alcorn | 8 years ago Use of generic versions of direct-acting antivirals resulted in very high cure rates for people who......MORE |
Tests of online PrEP purchases by London clinic find no fakes, and adequate drug levelsGus Cairns | 8 years ago A sexual health clinic in central London that offered to test drug levels in users of tenofovir/emt......MORE |
The benefit of treatment has outweighed the clinical impact of lipodystrophy, conference hearsGus Cairns | 8 years ago The 2016 Glasgow HIV Conference heard today that over a 20-year period, people who suffered lipodys......MORE |
French study reveals the growing complexity of medical needs as people with HIV ageKeith Alcorn | 8 years ago The complexity of the needs of people living with HIV will continue to increase as the population a......MORE |
Dolutegravir and central nervous system side-effects: abacavir, older age increase the riskKeith Alcorn | 8 years ago Insomnia, dizziness, headache and other central nervous system side effects are occurring more freq......MORE |
Some of the Americans who need PrEP the most face the greatest barriers to getting itRoger Pebody | 8 years ago The personal values and moral judgements of healthcare providers are likely to interfere with the a......MORE |
Two-drug HIV therapy just as effective as three-drug therapyKeith Alcorn | 8 years ago Simplification of an antiretroviral treatment to a boosted protease inhibitor and the nucleoside an......MORE |
As PrEP knowledge increases in San Francisco, 12,500 people now thought to be on PrEPLiz Highleyman | 8 years ago Knowledge about and use of HIV pre-exposure prophylaxis (PrEP) has greatly increased over the past ......MORE |
New $90-$90-$90 target needed for global viral hepatitis, HIV and TB treatmentKeith Alcorn | 8 years ago The costs of making drugs to treat viral hepatitis, HIV and TB are now so low that each disease cou......MORE |
New HIV prevention products will need marketing and effective health services to reach the people who need themRoger Pebody | 8 years ago There is a naivety among many HIV prevention researchers and advocates about the steps needed to in......MORE |
Huge diversity in current HIV vaccine research, Research for Prevention conference hearsGus Cairns | 8 years ago The HIV vaccine research field is currently going through probably its most fertile and diverse per......MORE |
New microbicide enema achieves high levels of drug in rectal tissues in monkeysGus Cairns | 8 years ago Rectal microbicides that protect against HIV transmission via anal sex are a bigger technical chall......MORE |
Rings, films or inserts? Researchers need to develop prevention products that make sense in women’s livesRoger Pebody | 8 years ago “We need to think outside of the box,” Sharon Hillier of the Microbicide Trials Network told th......MORE |
Vaginal and rectal bacteria may have a big influence on HIV transmission and microbicide efficacyGus Cairns | 8 years ago A number of presentations at the 2016 HIV Research for Prevention Conference (HIVR4P) in Chicago lo......MORE |
Controlling the HIV epidemic: ambitious funding, expanded workforce, innovations and micro-focus neededKeith Alcorn | 8 years ago Advocates who seek to end AIDS by 2030 should be ready to call on Hillary Clinton to massively incr......MORE |
Policy makers’ inaction is leading people to take PrEP ‘in the wild’Roger Pebody | 8 years ago An increasing number of gay men and others at risk of HIV are seeking to protect their health with ......MORE |
Anal sex may transmit four in ten HIV infections in US women at high riskGus Cairns | 8 years ago A study presented at the 2016 HIV Research for Prevention (HIVR4P) Conference in Chicago, USA sugge......MORE |
Second case report of PrEP failure due to drug-resistant virusRoger Pebody | 8 years ago A PrEP user in New York City has become HIV positive with virus that is resistant to Truvada and ot......MORE |
Mental health disorders common among people with HIV in British ColumbiaMichael Carter | 8 years ago Over 50% of people with HIV, many from disenfranchised groups, in British Columbia, Canada, are liv......MORE |
Crohn’s disease drug produces long-lasting viral undetectability and T-cell restoration off treatment in monkeysGus Cairns | 8 years ago In a promising experiment in rhesus macaque monkeys, scientists from Emory University in Atlanta ha......MORE |
Doctors in Netherlands observe higher than expected dolutegravir treatment discontinuation rateMichael Carter | 8 years ago Almost one in seven people in a Dutch clinic population stopped treatment with the HIV integrase in......MORE |
Less than 100% adherence to HIV therapy, even with viral suppression, can lead to more inflammation and immune activationMichael Carter | 8 years ago Research involving men taking antiretroviral therapy, all with an undetectable viral load, has show......MORE |
Educational attainment associated with health outcomes after starting HIV therapyMichael Carter | 8 years ago People with HIV who have lower educational attainment have poorer outcomes after starting combinati......MORE |
No evidence that contaminated nelfinavir led to increased risk of birth abnormalities or cancerMichael Carter | 8 years ago HIV-negative infants potentially exposed in utero to doses of the HIV protease inhibitor nelfinavir......MORE |
Promising trends continue in UK diagnosis and treatment ratesGus Cairns | 8 years ago A ‘mini report’ of the latest figures on HIV diagnoses, late diagnosis, and treatment uptake in......MORE |
Hepatitis B testing should be done before hepatitis C treatment due to risk of HBV reactivationLiz Highleyman | 8 years ago People considering direct-acting antiviral (DAA) therapy for hepatitis C should first be tested for......MORE |
Gay men with overlapping partnerships are more likely to be recently and locally infectedGus Cairns | 8 years ago A study analysing transmission patterns between gay men in a cohort of patients on San Diego, Calif......MORE |
100% cure rate for people with HCV genotype 1 treated with AL-335, odalasvir and simeprevir for 6 or 8 weeksLiz Highleyman | 8 years ago A triple regimen containing two experimental hepatitis C drugs – AL-335 and odalasvir – plus si......MORE |
Young people say that sex and relationships education in schools is negative and out of touchRoger Pebody | 8 years ago A review of 55 separate studies of sex and relationships education (SRE) in schools shows that youn......MORE |
Media reports of a British HIV cure 'breakthrough' are prematureKeith Alcorn | 8 years ago The Sunday Times yesterday reported that HIV had become undetectable in the blood of one man takin......MORE |
Hepatitis C infection and reinfection among men who have sex with men need higher priority, US and European studies showLiz Highleyman | 8 years ago Public health officials in Michigan have identified a cluster of more than 20 cases of apparently s......MORE |
Syphilis rates rising among gay men in US, CDC data showLiz Highleyman | 8 years ago New state-level data reveal that syphilis cases continue to rise among gay and bisexual men in the ......MORE |
Risk of reinfection is a concern after successful hepatitis C treatmentLiz Highleyman | 8 years ago People on opiate agonist substitution therapy can be successfully treated with grazoprevir/elbasvir......MORE |
Dutch model finds PrEP for high-risk gay men is cost-effective at current prices and cost-saving at generic pricesGus Cairns | 8 years ago A mathematical modelling study based on the HIV epidemic in the Netherlands has found that daily Pr......MORE |
EASL issues new hepatitis C treatment recommendations for all genotypesLiz Highleyman | 8 years ago The European Association for the Study of the Liver (EASL) released its latest recommendations on t......MORE |
Structural inequalities create vulnerability to HIV for black gay men in New YorkRoger Pebody | 8 years ago The sexual relationships of many African American men who have sex with men are largely shaped by e......MORE |
Early infant HIV testing at birth and at 6 weeks of age will save lives, extend life expectancy and is cost-effective for South Africa, study findsMichael Carter | 8 years ago Early infant HIV diagnosis in South Africa will save lives, extend life expectancy and be cost-effe......MORE |
Spanish study gives reassurance: small HIV blips do not predict treatment failureMichael Carter | 8 years ago A very low viral load (20-49 copies/ml) during HIV therapy does not increase the risk of the subseq......MORE |
HCV treatment is effective and may work as prevention for people who inject drugsLiz Highleyman | 8 years ago Hepatitis C treatment for people who inject drugs is as safe and effective as it is for non-drug-us......MORE |
New York clinic outlines how to improve uptake of PrEP by transgender peopleRoger Pebody | 8 years ago Dedicated efforts are needed to engage transgender men and women with clinical services and to enco......MORE |
Ugandan experience shows TB detection can be successfully incorporated into community HIV testing campaignsMichael Carter | 8 years ago Community health campaigns provide an opportunity to detect previously undiagnosed cases of tubercu......MORE |
Where would gay men prefer to take their next HIV test?Roger Pebody | 8 years ago Among English gay men who have never previously taken a test for HIV, self-testing and self-samplin......MORE |
Hepatitis C vaccine development shows progress but scientific barriers remainLiz Highleyman | 8 years ago An effective vaccine may be necessary to eliminate hepatitis C virus (HCV) but development has been......MORE |
Sweden the first country to achieve UNAIDS/WHO 90-90-90 targetMichael Carter | 8 years ago Sweden has become the first country to achieve the UNAIDS/WHO 90-90-90 target, research published i......MORE |
Managing non-communicable diseases among people living with HIVTheo Smart | 8 years ago Non-communicable diseases - including cardiovascular diseases, diabetes, cancers, and other illnes......MORE |
Delays in updating HIV treatment guidelines in Africa blocking early treatment for millionsKeith Alcorn | 8 years ago Delays in adopting the World Health Organization’s 2015 recommendation of HIV treatment for all t......MORE |
Effective antiviral treatment reduces fatigue in people with chronic hepatitis CLiz Highleyman | 8 years ago Fatigue – a common symptom among people living with hepatitis C virus (HCV) infection – is asso......MORE |
INHSU 2016 opens with focus on hepatitis C prevention and treatment for people who inject drugsLiz Highleyman | 8 years ago The 5th International Symposium on Hepatitis Care in Substance Users (INHSU 2016) got underway yest......MORE |
London gay men anticipate some pros and cons of different PrEP methods – but optimal efficacy is key to acceptabilityRoger Pebody | 8 years ago When presented with a range of possible HIV prevention technologies – a daily pill, pills before ......MORE |
Acceptability of PrEP for London gay men affected by perception of risk, sexual partners’ attitudes and the stigmatisation of sexRoger Pebody | 8 years ago PrEP is broadly acceptable to London gay men who are at risk of acquiring HIV, with many men seeing......MORE |
Life expectancy of patients starting HIV therapy differs sharply between high and middle/low income countriesMichael Carter | 8 years ago There are significant disparities in the life expectancy of HIV-positive patients starting combinat......MORE |
Life expectancy of people starting HIV therapy differs sharply between high- and middle/low-income countriesMichael Carter | 8 years ago There are significant disparities in the life expectancy of HIV-positive people starting combinatio......MORE |
HIV-positive gay and bisexual men have increased risk of hospitalisation with anxiety and mood disorders, a risk factor for later mortalityMichael Carter | 8 years ago HIV-positive gay and bisexual men are almost ten times more likely to be hospitalised because of mo......MORE |
Statins reduce risk of progression to cirrhosis in people with HIV/HCV co-infectionMichael Carter | 8 years ago Treatment with statins decreases the risk of progression to liver cirrhosis in people with HIV and ......MORE |
Statins reduce risk of progression to cirrhosis in HIV/HCV-co-infected peopleMichael Carter | 8 years ago Treatment with statins decreases the risk of progression to liver cirrhosis in people co-infected w......MORE |
San Francisco reports new low in HIV infections and faster treatment, but disparities remainLiz Highleyman | 8 years ago On September 1 the San Francisco Department of Public Health released its HIV Epidemiology Annual R......MORE |
Improvements in HIV treatment and care have had no impact on rates of endstage liver disease among HIV-positive people with viral hepatitisMichael Carter | 8 years ago Incidence of endstage liver disease (ESLD) among HIV-positive people with viral hepatitis changed l......MORE |
Improvements in HIV treatment and care have had no impact on rates of endstage liver disease among HIV-positive patients with viral hepatitisMichael Carter | 8 years ago Incidence of endstage liver disease (ESLD) among HIV-positive patients with viral hepatitis changed......MORE |
Vaginal ring for HIV prevention effective and acceptableRoger Pebody | 8 years ago An updated adherence analysis from the ASPIRE study indicates that consistent users of a vaginal ri......MORE |
Study looks at use of PrEP during pregnancy and breastfeedingLiz Highleyman | 8 years ago Women in San Francisco and the New York City frequently chose to use Truvada for pre-exposure prop......MORE |
Realism needed about the benefits and risks of taking part in HIV cure studiesRoger Pebody | 8 years ago A significant proportion of people living with HIV would be willing to take part in a study towards......MORE |
Depression increases risk of heart attack for adults with HIVMichael Carter | 8 years ago Major depression is associated with an increased risk of heart attack for middle-aged HIV-positive ......MORE |
Elevated lipids associated with cognitive decline in middle-aged HIV-positive men doing well on ARTMichael Carter | 8 years ago Elevated cholesterol and a gene associated with Alzheimer’s risk in the general population are bo......MORE |
Elevated lipids associated with cognitive decline in middle aged HIV-positive men doing well on ARTMichael Carter | 8 years ago Elevated cholesterol and a gene associated with Alzheimer’s risk in the general population are bo......MORE |
US PrEP study achieves high levels of engagement and adherence among black men who have sex with menGus Cairns | 8 years ago What was described at the AIDS2016 conference as “The first PrEP trial devised and run by four bl......MORE |
Many people in the US with chronic hepatitis B not being properly monitoredMichael Carter | 8 years ago Many people with chronic hepatitis B (CHB) virus infection have infrequent medical monitoring, acco......MORE |
Neglect of infectious diseases in prisons highlighted at AIDS 2016Theo Smart | 8 years ago “Prisoners are among the most neglected of the key populations; they bear higher burdens of HIV, ......MORE |
HIV not a risk factor for fibrosis progression in people with hepatitis CMichael Carter | 8 years ago HIV co-infection is not associated with accelerated progression of liver fibrosis in people with he......MORE |
New WHO algorithm to prevent TB deaths in very ill people with HIVTheo Smart | 8 years ago The World Health Organization (WHO) has released a new diagnostic algorithm in order to reduce the ......MORE |
German medicines watchdog rejects ‘new tenofovir’ pillGus Cairns | 8 years ago The German health technology assessment agency IQWiG has announced that it finds no advantage in De......MORE |
How can clinical services engage men who have sex with men in Africa?Roger Pebody | 8 years ago Men who have sex with men living in African countries have an extremely high burden of HIV, Stefan ......MORE |
Poor kidney function associated with increased cardiovascular risk for people with HIVMichael Carter | 8 years ago Renal impairment is associated with an increased risk of cardiovascular disease (CVD) in HIV-positi......MORE |
Most contraceptives not linked to HIV infection, but Depo-Provera may raise riskLiz Highleyman | 8 years ago Birth control pills and some types of injectable and implanted contraceptives were not associated w......MORE |
Ongoing hepatitis B virus replication associated with higher mortality for people with HIVLiz Highleyman | 8 years ago People with HIV and hepatitis B virus (HBV) co-infection have more than double the risk of death if......MORE |
Vaginal bacteria increase HIV susceptibility and may reduce PrEP effectivenessLiz Highleyman | 8 years ago Overgrowth of a certain species of vaginal bacteria was associated with a 13-fold higher likelihood......MORE |
Most patients taking second-line ART in sub-Saharan Africa achieve viral suppression but there's a need for third-line treatment optionsMichael Carter | 8 years ago Approximately 85% of patients switched to protease inhibitor-based second-line antiretroviral (ART)......MORE |
Most people taking second-line ART in sub-Saharan Africa achieve viral suppression but there's a need for third-line treatment optionsMichael Carter | 8 years ago Approximately 85% of people switched to protease inhibitor-based second-line antiretroviral (ART) i......MORE |
No new HIV infections seen in San Francisco's Strut PrEP programmeLiz Highleyman | 8 years ago A community-based sexual health clinic in San Francisco has offered nurse-led pre-exposure prophyla......MORE |
Efavirenz appears to be associated with elevated suicide risk in START trialLiz Highleyman | 8 years ago Participants in the START treatment-timing trial who took antiretroviral regimens containing efavir......MORE |
A detectable CMV viral load could signal a high risk of mortality in older individuals hospitalised with HIV-associated TBTheo Smart | 8 years ago A study conducted in a cohort of hospitalised HIV-associated TB coinfected adults from Khayelitsha......MORE |
People shifting from paediatric to adult HIV care have a high risk of ART failureMichael Carter | 8 years ago HIV-positive adolescents and young adults are especially likely to experience the virological failu......MORE |
Patients shifting from paediatric to adult HIV care have a high risk of ART failureMichael Carter | 8 years ago HIV-positive adolescents and young adults are especially likely to experience the virological failu......MORE |
Package of prophylaxis against infections reduces the risk of death for people starting HIV treatment very lateKeith Alcorn | 8 years ago A package of enhanced prophylaxis against infections significantly reduced the risk of death in adu......MORE |
Ending AIDS by 2030 a distant prospect, global HIV incidence, prevalence, treatment coverage and mortality figures suggestMichael Carter | 8 years ago Remarkable progress has been made towards curbing the global HIV epidemic, but there is little chan......MORE |
AbbVie 3D and 2D hepatitis C combos work well for people with HIV and HCV co-infectionLiz Highleyman | 8 years ago AbbVie's paritaprevir-based 3D regimen for hepatitis C virus (HCV) genotype 1 and 2D regimen for ge......MORE |
START analysis looks at who benefits most from immediate HIV treatmentLiz Highleyman | 8 years ago Starting antiretroviral therapy (ART) soon after HIV diagnosis led to better outcomes than delayed ......MORE |
High Court rules NHS England is responsible for funding PrEPKeith Alcorn | 8 years ago A judicial review in the High Court has ruled that NHS England is responsible for funding pre-expos......MORE |
Training community health workers to perform intensified TB case finding associated with a surge in TB diagnoses in a rural Malawi studyTheo Smart | 8 years ago Intensified TB case finding (TB ICF) by community health workers was associated with a dramatic (20......MORE |
Searching for the next ‘Berlin patient’: doctors document bone-marrow recipients with HIVGus Cairns | 8 years ago The ‘Berlin patient’, Timothy Ray Brown, has now survived seven years off antiretroviral therap......MORE |
PrEP rollout recipients in France top 1000: full trial results report 97% effectivenessGus Cairns | 8 years ago Up to July 2016, 1077 people, 96.4% of them gay men, have started HIV pre-exposure prophylaxis (PrE......MORE |
PrEP rollout recipients in France top 1,000: full trial results report 97% effectivenessGus Cairns | 8 years ago Up to July 2016, 1077 people, 96.4% of them gay men, have started HIV pre-exposure prophylaxis (PrE......MORE |
Stigma persists in the undetectable eraRoger Pebody | 8 years ago In an era of widespread HIV treatment and undetectable viral load, stigma remains a persistent feat......MORE |
Reducing clinic visits can support retention in HIV care, African studies showKeith Alcorn | 8 years ago Interventions which reduce the need for people to attend clinics are proving highly successful in r......MORE |
High-dose rifampicin for TB treatment regimen may improve survival in people with low CD4 cell countsTheo Smart | 8 years ago More aggressive TB treatment using high dose of rifampicin, in addition to ARV treatment, could red......MORE |
Early HIV treatment: mothers say they need time to thinkCarole Leach-Lemens | 8 years ago Findings from the first randomised controlled trial to date evaluating postpartum antiretroviral th......MORE |
Mapping local HIV epidemics can help target resources to areas with the greatest needRoger Pebody | 8 years ago Global health agencies have recently put a new emphasis on geography. UNAIDS have called for progra......MORE |
Women with HIV have higher risk of loss to follow-up and death after deliveryCarole Leach-Lemens | 8 years ago Despite the widespread implementation of Option B+ (lifelong antiretroviral therapy (ART) for pregn......MORE |
Phone and home visit follow-up and appointment trackers improve retention in HIV care for pregnant women and new mothersCarole Leach-Lemens | 8 years ago Phone and home visit follow-ups, improved use of appointment books to track attendance and patient-......MORE |
Once-daily raltegravir works as well as twice-daily for initial HIV treatmentLiz Highleyman | 8 years ago A new formulation of the integrase inhibitor raltegravir (Isentress) taken once daily suppressed H......MORE |
Bone loss partially recovers after stopping PrEP, twice-yearly kidney monitoring is enough for mostLiz Highleyman | 8 years ago Young adults taking Truvada for pre-exposure prophylaxis (PrEP) experienced a modest decrease in bo......MORE |
Dolutegravir plus lamivudine dual therapy works well as initial HIV treatmentLiz Highleyman | 8 years ago A two-drug regimen of dolutegravir and the well-tolerated NRTI lamivudine led to sustained viral su......MORE |
Access to HIV home tests doubles the frequency of HIV testing in Australian gay menRoger Pebody | 8 years ago A randomised trial conducted with Australian gay men has shown that easy access to self-testing kit......MORE |
'Test and treat': large study fails to show an impact on new HIV infectionsRoger Pebody | 8 years ago The first major research study of ‘test and treat’ as a public health intervention to report it......MORE |
Earlier HIV treatment is not over-burdening health servicesKeith Alcorn | 8 years ago Earlier treatment initiation is not overwhelming rural health services in South Africa, but changes......MORE |
Long-acting injectable drugs work well for HIV maintenance therapyLiz Highleyman | 8 years ago Two long-acting injectable antiretrovirals – cabotegravir and rilpivirine – administered once e......MORE |
Viral load pilot study shows roll-out will depend on an educated workforceKeith Alcorn | 8 years ago For viral load testing to prevent treatment failure, drug resistance and onward transmission, treat......MORE |
World’s largest study of HIV self-testing gets off the groundRoger Pebody | 8 years ago Early data from STAR, the largest study yet of HIV self-testing, suggests that there is a strong de......MORE |
Australia adopts ambitious plan to use PrEP to ‘virtually eliminate’ HIV by 2020Gus Cairns | 8 years ago Australia plans an ambitious programme of pre-exposure prophylaxis (PrEP) provision for gay men at ......MORE |
Market constraints and uncertainties may limit the scale-up of HIV self-testingRoger Pebody | 8 years ago Four different HIV self-test products are now manufactured and approved for sale in the US and Euro......MORE |
Sofosbuvir/velpatasvir shows high cure rate in HIV/HCV co-infection studyLiz Highleyman | 8 years ago The once-daily co-formulation of sofosbuvir and velpatasvir was highly effective against all hepati......MORE |
Starting treatment on the day of HIV diagnosis improves retention and viral suppression, Haiti study showsKeith Alcorn | 8 years ago Interventions to improve linkage to care and retention in treatment which speed up the start of tre......MORE |
PrEP can further reduce the risk of HIV infection after a partner starts treatmentLiz Highleyman | 8 years ago Offering Truvada pre-exposure prophylaxis (PrEP) to the HIV-negative partner in a serodiscordant c......MORE |
Young gay men can do well on PrEP, but may need more supportLiz Highleyman | 8 years ago Young gay and bisexual men had good adherence to Truvada for pre-exposure prophylaxis (PrEP) during......MORE |
SEARCH study exceeds 90-90-90 targets after 2 years of 'test and treat' for HIV in rural East AfricaKeith Alcorn | 8 years ago A large study that embeds 'test and treat' for HIV within a larger multi-disease prevention campaig......MORE |
South Africa has driven mother-to-child HIV transmission down to 4%Carole Leach-Lemens | 8 years ago Mother-to-child transmission (MTCT) of HIV at population level was just over 4% at 18 months follow......MORE |
HIV will only be cured with combinations too, conference delegates hearGus Cairns | 8 years ago Curing people of HIV infection will have to involve combinations of drugs and approaches, just as H......MORE |
Progress towards 90-90-90 targets in southern Africa: find the men!Keith Alcorn | 8 years ago Studies of treatment cascade performance in South Africa and Namibia show large variations between ......MORE |
Far fewer people drop out of HIV care in South Africa than previously thoughtRoger Pebody | 8 years ago Previous research has considerably over-estimated the number of people living with HIV who stop att......MORE |
HIV criminalisation on the rise, especially in sub-Saharan AfricaLesley Odendal | 8 years ago Globally, 72 countries have adopted laws that specifically allow for HIV criminalisation, either be......MORE |
New strategy aims to end AIDS in children by 2020Keith Alcorn | 8 years ago A new strategy to end paediatric AIDS launched at the 21st International AIDS Conference in Durban,......MORE |
More confidence on zero risk: still no transmissions seen from people with an undetectable viral load in PARTNER studyGus Cairns | 8 years ago The PARTNER study, which two years ago created headlines by establishing that the chance of an HIV-......MORE |
It’s all go for a new HIV vaccine efficacy trial this yearGus Cairns | 8 years ago A new efficacy trial for an HIV vaccine – only the seventh ever conducted in the history of the e......MORE |
Comprehensive services for sex workers reduce detectable viral load, but enhanced ARV services provide no extra benefitRoger Pebody | 8 years ago A randomised trial in female sex workers in Zimbabwe, offering enhanced access to HIV treatment and......MORE |
HIV treatment programmes need to prepare for the 'youth bulge', South African experience showsCarole Leach-Lemens | 8 years ago Treatment programmes in sub-Saharan Africa must prepare for a growing population of adolescents ove......MORE |
PrEP use exceeds 79,000 in US pharmacy survey, but some groups lagging behindLiz Highleyman | 8 years ago More than 79,000 people in the US have started Truvada for pre-exposure prophylaxis (PrEP) over the......MORE |
Strong association between sexual violence and African women acquiring HIV in EuropeRoger Pebody | 8 years ago Migrant African women who have acquired HIV since moving to France are four times more likely to ha......MORE |
Gains in curbing HIV epidemic could be lost without continued commitment, AIDS 2016 speakers sayLiz Highleyman | 8 years ago Participants at the 21st International AIDS Conference (AIDS 2016), taking place this week in Durba......MORE |
TB2016 demands a global commitment to end TBTheo Smart | 8 years ago While much of TB 2016, held on the eve of AIDS 2016 from 16-17 July 2016 was devoted to the rapidly......MORE |
Progress towards 90-90-90 targets is promising, but funding is the critical step, says UNAIDS leaderKeith Alcorn | 8 years ago The 90-90-90 targets for testing, treatment and viral suppression are achievable by 2020 in many hi......MORE |
Young women treated in very early HIV infection stay HIV negative and preserve immune functionGus Cairns | 8 years ago A group of young South African women who were diagnosed in very early infection and immediately giv......MORE |
Shortened regimen for MDR-TB shows good results for childrenLesley Odendal | 8 years ago The use of the shortened 9-month treatment regimen for multidrug-resistant tuberculosis (MDR-TB), k......MORE |
PrEP researchers now focusing on the best ways to get PrEP to people who need itRoger Pebody | 8 years ago Speaking to a pre-conference meeting on pre-exposure prophylaxis (PrEP) yesterday at the 21st Inter......MORE |
Opioid substitution therapy improves many ART-related outcomes among people who inject drugsMichael Carter | 8 years ago Opioid substitution therapy has a key roll in improving antiretroviral therapy (ART)-related outcom......MORE |
Most young MSM and transgender women, including those with HIV, would benefit from HPV vaccinationMichael Carter | 8 years ago Most young gay, bisexual and other men who have sex with men (MSM) would benefit from human papillo......MORE |
Incidence of liver cancer is increasing in patients with HIV/HCV co-infectionMichael Carter | 8 years ago Incidence of liver cancer is increasing among patients with HIV co-infection, an international team......MORE |
Incidence of liver cancer is increasing in people with HIV/HCV co-infectionMichael Carter | 8 years ago Incidence of liver cancer is increasing among people with HIV co-infection, an international team o......MORE |
Switching from tenofovir DF to TAF improves bone and kidney safetyLiz Highleyman | 8 years ago People with HIV who switched from the older tenofovir disoproxil fumarate (TDF) formulation to teno......MORE |
Feasible to prescribe ART to emergency department patients with suspected acute HIV infectionMichael Carter | 8 years ago Empiric antiretroviral therapy (ART) for individuals presenting to emergency departments with suspe......MORE |
HIV seroconversion is rare if Truvada PrEP is used consistentlyLiz Highleyman | 8 years ago New HIV infections occurred at a low rate of about 1 per 100 person-years among people who took dai......MORE |
New integrase inhibitor bictegravir looks promising in early studiesLiz Highleyman | 8 years ago Gilead Sciences' novel integrase inhibitor bictegravir (formerly GS-9883) demonstrated favourable p......MORE |
Atripla three times weekly maintains HIV viral suppression for 24 weeksLiz Highleyman | 8 years ago People with undetectable viral load who switched from taking the Atripla single-tablet regimen (efa......MORE |
VACS Index score can help identify HIV-positive people most at risk of neurocognitive declineMichael Carter | 8 years ago A combination of simple, routine blood tests may be able to predict which people living with HIV ar......MORE |
VACS Index score can help identify HIV-positive patients most at risk of neurocognitive declineMichael Carter | 8 years ago A combination of simple, routine blood tests may be able to predict which HIV-positive patients are......MORE |
Gay and bisexual people really do have poorer mental health, national US health survey showsGus Cairns | 8 years ago The inclusion, for the first time, of a question about sexual orientation in a regularly-conducted ......MORE |
Vaccination could have important role in control of UK HCV epidemic among people who inject drugsMichael Carter | 8 years ago A vaccine, even with low efficacy, could lead to meaningful reductions in the incidence and prevale......MORE |
PRO 140 antibody injections maintain viral suppression in phase 2 studyLiz Highleyman | 8 years ago Subcutaneous injections of PRO 140, a monoclonal antibody that blocks HIV entry into cells, was wel......MORE |
PRO-140 antibody injections maintain viral suppression in phase 2 studyLiz Highleyman | 8 years ago Subcutaneous injections of PRO 140, a monoclonal antibody that blocks HIV entry into cells, was wel......MORE |
US National HIV Testing Day boosts numbers testingRoger Pebody | 8 years ago Today, June 27, is National HIV Testing Day in the United States and a study just published in Morb......MORE |
ART use averting huge numbers of opportunistic infections among children living with HIV in lower-income countriesMichael Carter | 8 years ago There has been a decrease in cases of many opportunistic infections (OIs) among children living wit......MORE |
ART use averting huge numbers of opportunistic infections among HIV-positive children in lower-income countriesMichael Carter | 8 years ago There has been a decrease in cases of many opportunistic infections (OIs) among HIV-positive childr......MORE |
PrEP use is rising fast in US, but large racial disparities remainLiz Highleyman | 8 years ago More than 49,000 people in the US have filled prescriptions for Truvada for pre-exposure prophylaxi......MORE |
Hepatitis C antigen testing could eliminate need for two-step HCV testing, reduce cost of accessKeith Alcorn | 8 years ago Testing for hepatitis C virus core antigen could eventually replace the current two-step procedure......MORE |
Gay men report a wide range of behaviours to make sex saferRoger Pebody | 8 years ago Gay men in the UK employ a wide range of precautionary tactics and behaviours to avoid harms during......MORE |
Many US communities vulnerable to HIV outbreak due to unsafe injecting of prescription opioidsMichael Carter | 8 years ago Research published in the online edition of the Journal of Acquired Immune Deficiency Syndromes has......MORE |
Women in HIV serodiscordant relationships less likely to take PrEP consistently if they experience intimate partner violenceMichael Carter | 8 years ago Experiencing intimate partner violence is associated with an increased risk of poor adherence to HI......MORE |
People who inject drugs have other priorities ahead of PrEPRoger Pebody | 8 years ago People who inject drugs have fundamental concerns about HIV pre-exposure prophylaxis and the manner......MORE |
HIV treatment reduces HIV transmission by 77% in South African couplesKeith Alcorn | 8 years ago Antiretroviral treatment reduced the risk of HIV transmission by 77% in serodiscordant couples in r......MORE |
HIV testing and treatment campaigns need to target women and the under 35s, says research from South AfricaMichael Carter | 8 years ago A quarter of HIV-positive individuals in KwaZulu-Natal are unaware of their infection status, accor......MORE |
Sofosbuvir/ledipasvir regimens can cost less per cure than older hepatitis C treatmentsKeith Alcorn | 8 years ago The cost of treating chronic hepatitis C with sofosbuvir/ledipasvir (Harvoni) is lower than the cos......MORE |
Sofosbuvir/ledipasvir regimens can cost less per cure than older hepatitis C treatmentsLiz Highleyman | 8 years ago The cost of treating chronic hepatitis C with sofosbuvir/ledipasvir (Harvoni) is lower than the cos......MORE |
HIV-positive adolescents need to be rapidly linked to specialist care to have best chances of sustaining engagement with HIV servicesMichael Carter | 8 years ago Adolescents newly diagnosed with HIV need to be rapidly incorporated into HIV care networks to have......MORE |
Adolescents with HIV need to be rapidly linked to specialist care to have best chances of sustaining engagement with HIV servicesMichael Carter | 8 years ago Adolescents newly diagnosed with HIV need to be rapidly incorporated into HIV care networks to have......MORE |
Less frequent CD4 and viral load monitoring safe for people doing well on ARTMichael Carter | 8 years ago The frequency of routine monitoring for people treated with antiretrovirals with viral suppression ......MORE |
Big increases in proportion of HIV-positive patients in US treated with ART and with viral suppressionMichael Carter | 8 years ago The proportion of HIV-positive patients receiving care in the United States who accessed antiretrov......MORE |
Big increases in proportion of HIV-positive people in US treated with ART and with viral suppressionMichael Carter | 8 years ago The proportion of people living with HIV receiving care in the United States who accessed antiretro......MORE |
New HCV therapies unaffordable to health systems and individualsMichael Carter | 8 years ago The pricing of new treatments for hepatitis C virus (HCV) means they are unaffordable for many heal......MORE |
Sub-type C infection does not increase the risk of virologic failure when patients are taking tenofovir-containing first-line ARTMichael Carter | 8 years ago There is no evidence that HIV-positive patients with sub-type C infection have an increased risk of......MORE |
Sub-type C infection does not increase the risk of virologic failure when people are taking tenofovir-containing first-line ARTMichael Carter | 8 years ago There is no evidence that HIV-positive people with sub-type C infection have an increased risk of t......MORE |
UN High-Level Meeting on Ending AIDS faces battle over key populationsKeith Alcorn | 8 years ago Activists say that a United Nations Political Declaration on Ending AIDS, due to be finalised this ......MORE |
HIV self-testing has several advantages, but some barriers to HIV testing likely to remainRoger Pebody | 8 years ago A service offering kits for HIV self-testing in South Africa has the potential to improve uptake of......MORE |
Australia shows an alternative to rationing hepatitis C treatmentKeith Alcorn | 8 years ago The Hepatitis C Trust has announced it is considering seeking judicial review of NHS England's deci......MORE |
Significant attrition at each stage of HIV care cascade in South AfricaMichael Carter | 8 years ago There is significant attrition at each stage of the HIV care continuum in South Africa, according t......MORE |
Cost is biggest barrier to PrEP in Europe, ECDC declaresGus Cairns | 8 years ago A meeting a month ago at the European Centre for Disease Control (ECDC) in Stockholm found that cos......MORE |
Cost is biggest barrier to PrEP in Europe, ECDC report declaresGus Cairns | 8 years ago A meeting a month ago at the European Centre for Disease Control (ECDC) in Stockholm found that cos......MORE |
France to provide universal access to hepatitis C treatmentKeith Alcorn | 8 years ago France will provide access to hepatitis C treatment with direct-acting antivirals to everyone diagn......MORE |
Many South African patients whose HIV has been diagnosed have unprotected sex with a serodiscordant partner before starting ARTMichael Carter | 8 years ago Among a sample of South Africans living with diagnosed HIV infection in South Africa and waiting to......MORE |
Many South African patients whose HIV has been diagnosed have unprotected sex with a serodiscrodant partner before starting ARTMichael Carter | 8 years ago Among a sample of South Africans living with diagnosed HIV infection in South Africa and waiting to......MORE |
Many South African people whose HIV has been diagnosed have unprotected sex with a serodiscordant partner before starting ARTMichael Carter | 8 years ago Among a sample of South Africans living with diagnosed HIV infection in South Africa and waiting to......MORE |
Two million people with HIV started treatment in 2015Keith Alcorn | 8 years ago At least two million people worldwide started antiretroviral treatment in 2015 alone, and 17 millio......MORE |
2 million people with HIV started treatment in 2015Keith Alcorn | 8 years ago At least two million people worldwide started antiretroviral treatment in 2015 alone, and 17 millio......MORE |
Very high levels of drug resistance seen in patients failing first-line antiretroviral therapy in KenyaGus Cairns | 8 years ago A cross-sectional survey of viral load in patients attending the largest clinic providing antiretro......MORE |
Very high levels of drug resistance seen in people experiencing first-line antiretroviral therapy failure in KenyaGus Cairns | 8 years ago A cross-sectional survey of viral load in patients attending the largest clinic providing antiretro......MORE |
Rare but severe liver side-effects reported among South African patients starting efavirenz-based ARTMichael Carter | 8 years ago Treatment with efavirenz has been associated with rare but severe liver complications among patient......MORE |
AIDS patients have increased risk of death due to non-AIDS-related cancersMichael Carter | 8 years ago People diagnosed with AIDS have a very high risk of dying of a non-AIDS-defining cancer, Italian in......MORE |
People diagnosed with AIDS have increased risk of death due to non-AIDS-related cancersMichael Carter | 8 years ago People diagnosed with AIDS have a very high risk of dying of a non-AIDS-defining cancer, Italian in......MORE |
Only treating patients with cirrhosis with DAAs will have limited impact on HCV epidemic in EnglandMichael Carter | 8 years ago Targeting new hepatitis C virus (HCV) direct acting antivirals (DAAs) at patients with cirrhosis wi......MORE |
American gay men’s use of condoms has been falling for a decade, regardless of sero-sorting or PrEPRoger Pebody | 8 years ago There has been a long-term decline in condom use by American gay men, researchers from the Centers......MORE |
American gay men’s use of condoms has been falling for a decade, regardless of serosorting or PrEPRoger Pebody | 8 years ago There has been a long-term decline in condom use by American gay men, researchers from the Centers......MORE |
HIV/HBV co-infection linked to worse immune recovery and death, but tenofovir improves outcomesLiz Highleyman | 8 years ago HIV-positive people with hepatitis B virus (HBV) co-infection had impaired CD4 cell recovery after ......MORE |
Poor mental health more commonly experienced by gay and bisexual men who are younger, poorer, less educated or blackRoger Pebody | 8 years ago While it is well established that men who have sex with men are more likely to experience poor ment......MORE |
In Option B+, side-effects and needing time to think are key reasons for not taking HIV medicationRoger Pebody | 8 years ago A qualitative study of women in Malawi who chose not to take HIV treatment as part of the country......MORE |
Denmark shows first clear evidence of the success of treatment as prevention in gay men in a high income countryGus Cairns | 8 years ago A study by the University of California, Los Angeles, and Copenhagen University Hospital provides t......MORE |
Successful diagnosis of acute/early HIV infections may have contributed to fall in HIV incidence in San DiegoMichael Carter | 8 years ago An HIV testing programme targeting individuals with acute/early infection likely contributed to a d......MORE |
HIV rapidly develops resistance to gene-editing cure technologyGus Cairns | 8 years ago In a setback for a novel approach to curing HIV, researchers involved in a technique that uses enzy......MORE |
Does having HIV affect response to hepatitis C treatment?Liz Highleyman | 8 years ago A study from the US Veterans Health Administration found that HIV-positive people responded as well......MORE |
Hypertension in patients with HIV associated with obesity, fat loss and previous treatment with stavudineMichael Carter | 8 years ago Patients with HIV have a higher prevalence of hypertension than closely matched HIV-negative contro......MORE |
WHO issues new hepatitis C guidelines, EASL guidelines update forthcoming in SeptemberLiz Highleyman | 8 years ago In April, coinciding with the 2016 International Liver Congress in Barcelona, the World Health Orga......MORE |
Men taking virologically suppressive ART have undetectable HIV in their pre-ejaculatory fluidMichael Carter | 8 years ago HIV is undetectable in the pre-ejaculatory fluid of men taking suppressive antiretroviral therapy, ......MORE |
Small risk of sexual transmission of HIV persists through first six months of ARTMichael Carter | 8 years ago A risk of HIV transmission to sexual partners persists for six months after the initiation of antir......MORE |
US on course to end its HIV epidemic – eventuallyGus Cairns | 8 years ago If current trends continue, the US may eventually end its HIV epidemic, a mathematical model recent......MORE |
HCV associated with increased risk of cancers of the head and neckMichael Carter | 8 years ago Infection with hepatitis C virus (HCV) is associated with an increased risk of head and neck cancer......MORE |
Hepatitis C kills more people than any other infectious disease in US, CDC saysLiz Highleyman | 8 years ago The number of deaths due to hepatitis C is at an all-time high in the US and exceeds those attribu......MORE |
Hepatitis C therapy improves quality of life for people who inject drugs, but reinfection risk remainsKeith Alcorn | 8 years ago People on opiate substitution therapy can be successfully treated with grazoprevir/elbasvir (Zepati......MORE |
High prevalence of geriatric conditions in HIV-positive patients aged over 50 in San FranciscoMichael Carter | 8 years ago Older HIV-positive patients have a high prevalence of multiple age-related problems, investigators ......MORE |
China has a long way to go before it achieves 90-90-90 targetsMichael Carter | 8 years ago A study published in Clinical Infectious Diseases suggests that China has a long way to go before i......MORE |
Which men stand to benefit most from access to PrEP?Michael Carter | 8 years ago New data from the PROUD pre-exposure prophylaxis (PrEP) study have identified the characteristics o......MORE |
How do gay men diagnosed with HIV change their risk behaviour?Gus Cairns | 8 years ago To what extent do gay men modify their sexual risk behaviour after testing HIV positive? Two Austra......MORE |
People treated for hepatitis C have unexpectedly high rate of liver cancer recurrenceLiz Highleyman | 8 years ago Hepatitis C patients with cirrhosis who were treated with direct-acting antivirals had about twice ......MORE |
ART use doesn't increase sexual risk among people with HIV in the UKMichael Carter | 8 years ago Taking antiretroviral therapy (ART) is not associated with an increased risk of condomless sex with......MORE |
More targeted interventions to diagnose HIV during acute infection are needed, researchers warnMichael Carter | 8 years ago Men who have sex with men (MSM) diagnosed with HIV in the acute phase of HIV infection have a great......MORE |
Portugal's roll-out of HCV therapy with DAAs achieves impressive resultsMichael Carter | 8 years ago Roll-out of hepatitis C virus (HCV) therapy using direct acting antivirals (DAAs) has achieved exce......MORE |
First data on uptake of HIV self-testing in the UKRoger Pebody | 8 years ago Between April 2015 and February 2016, almost 28,000 people have paid £29.95 for a kit allowing the......MORE |
Opt-out HIV testing in a hospital emergency department may cost less than managing two patients with undiagnosed HIVRoger Pebody | 8 years ago Opt-out HIV testing in accident and emergency departments in areas of high HIV prevalence is likely......MORE |
Considerable overlap between HIV and shigellosis epidemics in the UKMichael Carter | 8 years ago Approximately a third of cases of non-travel-related Shigella dysentery in the UK involve HIV-posit......MORE |
Considerable overlap between HIV and Shigella epidemics in the UKMichael Carter | 8 years ago Approximately a third of cases of non-travel-related Shigella dysentery in the UK involve HIV-posit......MORE |
Online privacy concerns limit the reach of sexual health messages on social mediaRoger Pebody | 8 years ago The way in which individuals manage their identities on Facebook, for example avoiding publication ......MORE |
Multiple social and health factors associated with irregular attendance at London HIV clinicsRoger Pebody | 8 years ago People who miss appointments for HIV care are more likely to have money problems, childcare respons......MORE |
DAAs achieve excellent outcomes in real-world settingsMichael Carter | 8 years ago Hepatitis C virus (HCV) therapy with direct acting antivirals (DAAs) is as effective in real-world ......MORE |
Model suggests there are fewer people with HIV in the US than thought, and more of them on therapyGus Cairns | 8 years ago A study comparing recorded diagnoses of HIV with subsequent records of viral load and CD4 tests sug......MORE |
High incidence of HCV re-infection among HIV-positive MSM in Western EuropeMichael Carter | 8 years ago There is a very high incidence of hepatitis C virus (HCV) re-infection among HIV-positive men who h......MORE |
Sofosbuvir/velpatasvir cures HCV in 95% of people with HCV and HIV co-infectionLiz Highleyman | 8 years ago A dual regimen of sofosbuvir plus velpatasvir was well tolerated and highly effective against hepat......MORE |
Six weeks of sofosbuvir/ledipasvir is enough to cure acute hepatitis C in HIV-negative peopleLiz Highleyman | 8 years ago A regimen of sofosbuvir/ledipasvir (Harvoni) taken for six weeks cured all patients with genotype 1......MORE |
Tenofovir alafenamide works well against hepatitis B with less effect on bones and kidneysLiz Highleyman | 8 years ago The new tenofovir alafenamide (TAF) pro-drug is as potent against hepatitis B virus (HBV) as the cu......MORE |
Low-cost generic hepatitis C drugs match branded products in viral responseKeith Alcorn | 8 years ago Generic versions of direct-acting antivirals purchased from China and India by people unable to obt......MORE |
Shifting hepatitis C treatment to primary care providers could expand availabilityLiz Highleyman | 8 years ago Hepatitis C treatment managed by non-specialists such as primary care physicians and nurse practiti......MORE |
Sofosbuvir/velpatasvir + GS-9857 works well for treatment-experienced hepatitis C patientsLiz Highleyman | 8 years ago A triple combination of Gilead Sciences' sofosbuvir, velpatasvir and GS-9857 demonstrated a high s......MORE |
Hepatitis C treatment may not be enough to stop the progress of advanced liver disease, or reduce liver transplant needKeith Alcorn | 8 years ago Doctors need to have “full and frank” discussions with patients about the potential risks and b......MORE |
$300 hepatitis C combination to enter clinical trialsKeith Alcorn | 8 years ago The Drugs for Neglected Diseases Initiative (DNDI) is launching clinical trials in Thailand and Mal......MORE |
People not taking HIV treatment feel under pressure to ‘do the right thing’Roger Pebody | 8 years ago Australian people living with HIV who have chosen not to take antiretrovirals and who have doubts a......MORE |
Resistance to anti-HIV drugs in steep decline in SwitzerlandMichael Carter | 8 years ago Prevalence of antiretroviral drug resistance has declined significantly among patients in Switzerla......MORE |
Primary care doctors and nurse practitioners can successfully treat people with hepatitis CLiz Highleyman | 8 years ago Direct-acting antiviral therapy for hepatitis C delivered by non-specialists such as primary care p......MORE |
A third of MSM with HIV/HCV co-infection have HCV in their semenMichael Carter | 8 years ago Hepatitis C virus (HCV) is present in the semen of a third of co-infected HIV-positive men who have......MORE |
VRC01 antibody delays but does not prevent HIV rebound after antiretroviral treatment interruptionLiz Highleyman | 8 years ago VRC01, a broadly neutralising antibody targeting HIV's CD4 binding site, was able to modestly delay......MORE |
More people with HIV are achieving viral suppression in US, but about 40% remain above transmission thresholdsLiz Highleyman | 8 years ago A growing proportion of people with HIV are reaching an undetectable viral load on antiretroviral t......MORE |
Indian study proves that more people virally suppressed in a population equals fewer HIV infectionsGus Cairns | 8 years ago The proportion of people living with HIV in a population who have a detectable viral load is much m......MORE |
Simple outreach on dating websites increases HIV testing rateRoger Pebody | 8 years ago A simple online outreach intervention – in which a health educator engaged in conversation and re......MORE |
No adverse social consequences from early ART initiation in West AfricaMichael Carter | 8 years ago Early initiation of antiretroviral therapy (ART) does not have negative social consequences, invest......MORE |
HCV epidemic in North America peaked between 1940 and 1965 with medical procedures likely source of most infectionsMichael Carter | 8 years ago The spread of hepatitis C virus (HCV) in North America peaked between 1940 and 1965, according to r......MORE |
African women in London with poor adherence feel that HIV treatment is difficult and unrelentingRoger Pebody | 8 years ago A qualitative study with West African women living in London who have difficulties adhering to thei......MORE |
Long-acting oral antiretroviral MK-8591 could represent 'paradigm shift' in HIV treatment and prophylaxisMichael Carter | 8 years ago An investigational antiretroviral agent that maintains drug levels that are able to inhibit HIV up ......MORE |
Antidepressant modestly improves HIV-related cognitive impairmentLiz Highleyman | 8 years ago The SSRI antidepressant paroxetine (Paxil) was associated with modest improvement in cognitive func......MORE |
Gene therapy snips HIV out of infected cells and makes uninfected cells resistantGus Cairns | 8 years ago For the first time, researchers have used a gene-editing technique already used to produce cells re......MORE |
Gene therapy snips HIV out of infected cells and makes uninfected cells resistantGus Cairns | 8 years ago For the first time, researchers have used a gene-editing technique already used to produce cells re......MORE |
High-risk anal HPV infections persist in a significant proportion of HIV-negative MSMMichael Carter | 8 years ago Anal infection with human papillomavirus (HPV) types associated with a high risk of pre-cancerous a......MORE |
Isoniazid alone prevents tuberculosis in people with advanced HIV, urine test may lower mortalityLiz Highleyman | 8 years ago Using isoniazid alone to prevent the development of active tuberculosis (TB) in people with advance......MORE |
Tailored programmes encourage black gay men to start and stay on PrEP in US studyLiz Highleyman | 8 years ago Providing culturally tailored support programmes for black men who have sex with men can increase t......MORE |
England’s PrEP policy in disarray after NHS U-turnRoger Pebody | 8 years ago Activists, individuals at risk of HIV, and clinicians have reacted with anger to an official U-turn......MORE |
Opt-out HIV/HBV/HCV testing for patients attending emergency departments identifies significant number of new infectionsMichael Carter | 8 years ago A pilot study involving nine UK emergency departments has shown that routine, opt-out testing for H......MORE |
ART has averted over 850,000 HIV-related opportunistic infections in low and middle income countriesMichael Carter | 8 years ago Rollout of antiretroviral therapy (ART) in low and middle income countries has averted over 850,000......MORE |
Combination inhibitor BMS-986197 demonstrates good activity against HIV in early studyLiz Highleyman | 8 years ago A long-acting bio-engineered molecule with a triple mechanism of action demonstrated potent antivir......MORE |
Starting HIV therapy associated with improvements in liver function, especially when viral load is suppressedMichael Carter | 8 years ago Starting antiretroviral therapy is associated with improvements in liver function in HIV-positive m......MORE |
High sexually transmitted infection rates among men on PrEP supports more frequent monitoringLiz Highleyman | 8 years ago Participants taking tenofovir/emtricitabine (Truvada) for pre-exposure prophylaxis (PrEP) continued......MORE |
HIV-related factors increase risk of strokeTheo Smart | 8 years ago HIV-related risk factors seem to increase the risk of stroke – the sudden death of brain cells du......MORE |
Sofosbuvir/velpatasvir for hepatitis C can be administered with most antiretroviralsLiz Highleyman | 8 years ago Sofosbuvir/velpatasvir, a forthcoming combination that effectively treats all hepatitis C virus (HC......MORE |
Transgender people are at high risk for HIV, but too little is known about prevention and treatment for this populationLiz Highleyman | 8 years ago Transgender women have among the highest rates of HIV infection but little is known about HIV preva......MORE |
Rapid rise in PrEP awareness in US gay men, but only 5% have used PrEPRoger Pebody | 8 years ago Large internet surveys of American gay men show that the proportion who have heard of pre-exposure ......MORE |
Indiana HIV epidemic among people who inject drugs is controlled, but ongoing vigilance is neededLiz Highleyman | 8 years ago Extensive epidemiological investigation followed by prevention and treatment interventions have lar......MORE |
Ravidasvir plus sofosbuvir demonstrates high cure rate for people with hepatitis C genotype 4Liz Highleyman | 8 years ago Sofosbuvir plus the investigational HCV NS5A inhibitor ravidasvir, with or without ribavirin, cured......MORE |
START study shows that people starting HIV treatment earlier have better quality of lifeRoger Pebody | 8 years ago Rather than treatment side-effects having a negative impact on people’s quality of life when they......MORE |
South Africa’s XDR-TB epidemic is due to transmission rather than evolution of resistant strainsTheo Smart | 8 years ago A study in KwaZulu-Natal, South Africa, evaluating the social networks as well as clinical and geno......MORE |
Maraviroc may work as PrEP in combination with another drug – but probably not by itselfGus Cairns | 8 years ago Two studies presented at the Conference on Retroviruses and Opportunistic Infections (CROI 2016) ou......MORE |
Expanding treatment and PrEP could prevent 185,000 new HIV infections, US CDC saysLiz Highleyman | 8 years ago Increasing diagnosis, care and treatment of people living with HIV could lead to a large decrease i......MORE |
Modest kidney function decline in people taking Truvada for PrEP supports need for monitoringLiz Highleyman | 8 years ago Participants taking tenofovir/emtricitabine (Truvada) for pre-exposure prophylaxis (PrEP) in two ma......MORE |
Rate of entry into HIV care improved by personalised counsellingKeith Alcorn | 8 years ago Entry into HIV care can be increased by around 40% if people receive a point-of-care CD4 test and c......MORE |
Studies probe retention in HIV care for women who start antiretroviral treatment during pregnancyCarole Leach-Lemens | 8 years ago Engaging lay counsellors to provide a combination package of evidence-based interventions in Nyanza......MORE |
Experimental TLR7 agonist suppresses HIV-like virus in monkeys after ART interruptionLiz Highleyman | 8 years ago GS-9620, an investigational toll-like receptor or TLR7 agonist, led to immune activation in a stud......MORE |
Study does not support routine HPV quadrivalent vaccination to protect against anal cancer in older people living with HIVKeith Alcorn | 8 years ago The quadrivalent HPV vaccine Gardasil does not protect older adults with HIV against persistent ana......MORE |
‘On-demand’ rectal microbicide gel has reasonable tolerability and acceptability – daily less soGus Cairns | 8 years ago Results from the MTN-017 study of 1% tenofovir gel as a rectal microbicide were presented to the CR......MORE |
Life expectancy in HIV positive people in the US still lags 13 years behind HIV negative peopleGus Cairns | 8 years ago A study presented at the CROI 2016 conference comparing life expectancies of HIV-positive and HIV-n......MORE |
Life expectancy in HIV-positive people in the US still lags 13 years behind HIV-negative peopleGus Cairns | 8 years ago A study presented at the Conference on Retroviruses and Opportunistic Infections (CROI 2016) compar......MORE |
Option B+ has enabled Malawi to make significant progress towards 90-90-90Roger Pebody | 8 years ago In four years Malawi’s treatment cascade for pregnant women has been transformed so that the prop......MORE |
Condom use in French PrEP trial: half only used PrEP, a quarter used condoms and PrEP, one in six used neitherGus Cairns | 8 years ago An analysis of condom use in the placebo-controlled phase of the French IPERGAY trial of intermitte......MORE |
Empirical TB treatment comes up short againTheo Smart | 8 years ago A South African trial has found that a strategy allowing primary care nurses to quickly provide emp......MORE |
Sofosbuvir/ledipasvir for 6 weeks cures HCV in HIV-positive people with acute HCV if viral load is lowLiz Highleyman | 8 years ago An interferon- and ribavirin-free regimen of sofosbuvir/ledipasvir (Harvoni) taken for just 6 weeks......MORE |
Large-scale household TB screening shows feasibility in PopART trialKeith Alcorn | 8 years ago Offering TB screening as part of a home-based HIV testing intervention has the potential to identif......MORE |
Almost-certain case of PrEP failure due to drug resistance reported at CROI 2016Gus Cairns | 8 years ago A case report of a man in Toronto who became infected with a multi-drug-resistant strain of HIV des......MORE |
Almost-certain case of PrEP failure due to drug resistance reported at CROI conferenceGus Cairns | 8 years ago A case report of a man in Toronto who became infected with a multi-drug-resistant strain of HIV des......MORE |
Early antiretroviral therapy reduces the risk of infection-related cancersKeith Alcorn | 8 years ago People who started antiretroviral therapy at a CD4 cell count above 500 had a significantly lower ......MORE |
HIV in the brain: new tools and treatment to keep your mind beautifulTheo Smart | 8 years ago In the future, HIV-associated neurocognitive disorder (HAND) may become less common because of the ......MORE |
Removing clinic barriers to rapid initiation of ART in Uganda enables 70% to start on the same dayRoger Pebody | 8 years ago Making point-of-care CD4 count diagnostics available, revising adherence counselling requirements a......MORE |
Dolutegravir safe and highly effective in older childrenCarole Leach-Lemens | 8 years ago Dolutegravir (DTG) plus optimised background regimen (OBR) is safe, well tolerated and provides vir......MORE |
Long-acting PrEP injection tolerable and acceptable for male volunteers, but dose adjustment neededGus Cairns | 8 years ago The Conference on Retroviruses and Opportunistic Infections (CROI 2016) heard results yesterday fro......MORE |
Tenofovir alafenamide PrEP protects monkeys from infection, but rectal and vaginal levels in humans may be too lowLiz Highleyman | 8 years ago A proof-of-concept study showed that the new tenofovir alafenamide (TAF) plus emtricitabine (FTC, E......MORE |
TAF/emtricitabine maintains viral suppression as well as TDF regimens with less bone and kidney toxicityLiz Highleyman | 8 years ago A fixed-dose coformulation of tenofovir alafenamide (TAF) and emtricitabine (FTC, Emtriva), combine......MORE |
PopART trial shows feasibility of reaching 90-90-90 targets for testing and treatment coverage in Zambia and South AfricaKeith Alcorn | 8 years ago Early findings from the PopART study of the impact of a test-and-treat strategy on antiretroviral t......MORE |
Botswana close to reaching the 90-90-90 testing and treatment targetsKeith Alcorn | 8 years ago Botswana is already close to reaching the 90-90-90 target for testing, treatment and viral suppres......MORE |
Cotrimoxazole prophylaxis provides no benefit for HIV-exposed uninfected childrenCarole Leach-Lemens | 8 years ago Challenging current guidelines, prolonged use of cotrimoxazole (CTX) may not be necessary for HIV-e......MORE |
Partner notification feasible and effective in African settingsRoger Pebody | 8 years ago Partner notification programmes, offering HIV testing to the sexual partners of people newly diagno......MORE |
Very high levels of chemsex and ‘slamsex’ seen in HIV-positive men attending English/Welsh HIV clinicsGus Cairns | 8 years ago A survey of HIV-positive patients attending 30 HIV clinics in England and Wales, presented at the C......MORE |
Option B+ cuts mother-to-child HIV transmission dramatically in MalawiCarole Leach-Lemens | 8 years ago Among women on antiretroviral therapy (ART) prior to pregnancy, early mother-to-child transmission ......MORE |
Starting HIV treatment at first clinic visit improves outcomes in African studyLiz Highleyman | 8 years ago A programme to accelerate the process of HIV diagnosis, preparation and starting antiretroviral the......MORE |
Major disparities persist in lifetime risk of HIV diagnosis in the USLiz Highleyman | 8 years ago The lifetime risk of being diagnosed with HIV in the US has decreased overall during the past decad......MORE |
During pregnancy, offering HIV testing at home doubles the proportion of male partners who testRoger Pebody | 8 years ago A programme of home visits, partner education and HIV testing for couples in Kenya was able to doub......MORE |
People with HIV considerably overestimate their chance of infecting someoneGus Cairns | 8 years ago Only a small proportion of HIV-positive people in a large US treatment study, ACTG A5257, regarded ......MORE |
Bone density recovers quickly after stopping PREPKeith Alcorn | 8 years ago Bone mineral density recovers within six months of stopping pre-exposure prophylaxis (PrEP) contain......MORE |
Dose-finding trials of antibody-based drugs for HIV prevention will start soonGus Cairns | 8 years ago The next generation of pre-exposure prophylaxis (PrEP), and even of HIV treatment, may consist of a......MORE |
Long-acting injectable cabotegravir + rilpivirine works well as HIV maintenance therapyLiz Highleyman | 8 years ago A combination of two long-acting injectable antiretrovirals, cabotegravir and rilpivirine, given on......MORE |
Early antiretroviral therapy has no impact on marker of early cardiovascular diseaseKeith Alcorn | 8 years ago Starting treatment at a CD4 cell count above 500 does not lead to improvement in an important early......MORE |
Women and African-Americans with HIV have a higher risk of strokeKeith Alcorn | 8 years ago The risk of stroke among people living with HIV is highest among people with unsuppressed viral loa......MORE |
Tenofovir treatment raises the risk of broken bonesKeith Alcorn | 8 years ago Treatment containing tenofovir is associated with a higher risk of bone fractures in people living ......MORE |
Vaginal rings containing antiretroviral moderately effective in preventing HIV – but not in the youngest womenGus Cairns | 8 years ago The results of two studies announced today at the annual Conference on Retroviruses and Opportunist......MORE |
Survey shows more than 800,000 people in US have hepatitis B, half of them AsianLiz Highleyman | 8 years ago Although nearly 70 million people in the US have been vaccinated against hepatitis B virus (HBV), t......MORE |
Direct-acting antivirals reduce cryoglobulinemia in hepatitis CKeith Alcorn | 8 years ago Treatment with direct-acting antivirals not only cures people of hepatitis C, but can also rapidly ......MORE |
What do women want from a vaginal microbicide ring?Gus Cairns | 8 years ago In order to maximise confidence in its effectiveness, a vaginal microbicide ring for women would id......MORE |
Telephone intervention can boost retention in care for HIV-positive patients with mental health and drug/alcohol problemsMichael Carter | 8 years ago Retention in HIV care among patients with mental health and/or drug and alcohol problems can be imp......MORE |
PrEP use rising among high-risk gay men in Washington StateLiz Highleyman | 8 years ago More than 20% of gay and bisexual men in Washington State considered to be at high risk for HIV in......MORE |
HIV-infected vaginal cells do not transmit HIV if plasma viral load is undetectable, researchers findGus Cairns | 8 years ago A group of researchers, in experiments on mice, have cleared up an important question about HIV tra......MORE |
Survival and outcome analysis shows that selected HIV-positive patients are good candidates for liver and kidney transplantMichael Carter | 8 years ago Liver and kidney transplant can be justified for carefully selected HIV-positive patients, research......MORE |
Moderate alcohol consumption may be more harmful to people with HIVKeith Alcorn | 8 years ago Safe drinking limits for people living with HIV may be lower than the recommendations for the rest ......MORE |
Neurosyphilis present in 90% of HIV-positive patients with early syphilis in WarsawMichael Carter | 8 years ago The overwhelming majority of early syphilis cases in patients with HIV in Warsaw had neurological i......MORE |
African Americans have highest HIV incidence, lowest rate of consistent careLiz Highleyman | 8 years ago African Americans in the US have the highest rate of new HIV infections, but black people living w......MORE |
Women under-represented in HIV clinical trialsRoger Pebody | 8 years ago Less than a quarter of people taking part in clinical trials for antiretroviral medications are wom......MORE |
Combination nanotherapy drastically reduces the amount of HIV produced by cells in miceGus Cairns | 8 years ago A combination of fine-particle formulations of the drugs atazanavir and ritonavir, plus an immune-d......MORE |
Combination nanotherapy drastically reduces the amount of HIV inside cells in miceGus Cairns | 8 years ago A combination of fine-particle formulations of the drugs atazanavir and ritonavir, plus an immune-d......MORE |
Bladder cancer occurring earlier in people with HIV, and cases more difficult to treat, French study findsMichael Carter | 8 years ago The frequency of bladder cancer is elevated in patients with HIV, investigators from Paris report i......MORE |
Opt-out approach can boost HIV testing ratesRoger Pebody | 8 years ago A large randomised study in an emergency department in San Francisco clearly shows that an ‘opt-o......MORE |
Broad range of risk factors associated with mild cognitive impairment in HIV-positive men on ARTMichael Carter | 8 years ago A broad range of factors are associated with cognitive impairment in middle-aged HIV-positive men, ......MORE |
Tenofovir resistance may develop after HIV treatment failure in over half in sub-Saharan AfricaKeith Alcorn | 8 years ago More than half of people who experienced failure of a tenofovir-based antiretroviral regimen in sub......MORE |
Tenofovir resistance may develop in more than half of patients failing treatment in sub-Saharan AfricaKeith Alcorn | 8 years ago More than half of people who experienced failure of a tenofovir-based antiretroviral regimen in sub......MORE |
New Merck combination pill Zepatier approved for hepatitis C treatment in the United StatesKeith Alcorn | 8 years ago Merck has received a US license for its direct-acting antiviral combination of grazoprevir and elba......MORE |
Criminal laws on HIV transmission make little difference to sexual behaviour – or may make condomless sex more likelyRoger Pebody | 8 years ago A study comparing the sexual behaviour of American gay men living in states with or without laws th......MORE |
London sexual health clinics step up their support for people buying PrEP onlineRoger Pebody | 8 years ago Several large sexual health clinics in London and Brighton have responded to the growing numbers of......MORE |
US study shows importance of access to chemotherapy for HIV-positive patients with Hodgkin lymphomaMichael Carter | 8 years ago HIV is associated with poorer outcomes in patients diagnosed with Hodgkin lymphoma, according to US......MORE |
People taking a large number of non-HIV-related medications more likely to stop or change HIV drugsMichael Carter | 8 years ago HIV-positive patients who are taking a large number of medications for the treatment of non-HIV-rel......MORE |
New PrEP studies will be a challenge, statisticians warnGus Cairns | 8 years ago Two statisticians involved in the PROUD and iPrEx trials of pre-exposure prophylaxis (PrEP) warn th......MORE |
Model suggests HIV vaccine still has key role in ending AIDSLiz Highleyman | 8 years ago Even a modestly effective HIV vaccine would likely be cost-effective and could make a major contri......MORE |
Cardiovascular disease risk is higher for people with hepatitis CKeith Alcorn | 8 years ago People with hepatitis C are at higher risk of dying from cardiovascular disease suffering a stroke ......MORE |
D:A:D study: long-term treatment with tenofovir associated with increased risk of serious liver diseaseMichael Carter | 8 years ago Long-term therapy with the antiretroviral drug tenofovir increases the risk of end-stage liver dise......MORE |
Electrocautery ablation only partially effective as a treatment for high-grade pre-cancerous anal lesions in HIV-positive gay menMichael Carter | 8 years ago Electrocautery ablation is only partially effective as a treatment for high-grade pre-cancerous ana......MORE |
High rates of cervical disease and low rates of screening among women with HIV in DenmarkMichael Carter | 8 years ago Women with HIV have a higher incidence of cervical dysplasia – pre-cancerous cell changes – com......MORE |
Efavirenz-based treatment is safe and effective for young children with HIV exposed to nevirapine for PMTCTMichael Carter | 8 years ago Efavirenz-based treatment is a safe and effective treatment option for children living with HIV pre......MORE |
PrEP, plus increased testing and treatment, could prevent nearly half of HIV infections in gay men in the UK by 2020Gus Cairns | 8 years ago A new British mathematical modelling study published in The Lancet HIV has found that adding pre-e......MORE |
High rates of modifiable cancer risk factors present in Western HIV-positive patientsMichael Carter | 8 years ago The prevalence of potentially modifiable risk factors for some cancers is “extraordinarily high......MORE |
High prevalence of anal infection with high-risk HPV types among HIV-positive women in FranceMichael Carter | 8 years ago A large proportion of women living with HIV in a national study have an anal infection with types o......MORE |
Two cases of PrEP failure on solo tenofovir pose significant research questionsGus Cairns | 8 years ago A report originally presented to the 2015 BHIVA conference last year details two cases where therap......MORE |
MDR-TB treatment: Six drugs better than fiveKeith Alcorn | 8 years ago A regimen containing six drugs was more likely to cure multi-drug resistant tuberculosis (MDR-TB) t......MORE |
Middle-aged people living with HIV have an increased risk of frailtyMichael Carter | 8 years ago Middle-aged people living with HIV have an increased risk of frailty compared with their peers with......MORE |
Not having enough food linked with lower chances of sustained viral suppression for ART-treated breastfeeding mothers in UgandaMichael Carter | 8 years ago Not having enough food is associated with poorer chances of achieving a sustained viral suppression......MORE |
Hepatitis C virus linked to increased risk of Parkinson's disease, studies showLiz Highleyman | 8 years ago People with hepatitis C virus (HCV) infection may be more likely to develop Parkinson's disease, e......MORE |
HIV-positive patients lost to follow-up successfully identified and re-engaged with care by programme in LA CountyMichael Carter | 8 years ago A programme in Los Angeles County successfully re-engaged and retained patients who dropped out of ......MORE |
LAM point-of-care TB testing reduces mortality in people with HIV/TB co-infection in hospitalLesley Odendal | 8 years ago All-cause 8-week mortality is reduced by rapid point-of-care urine-based testing for tuberculosis (......MORE |
Annual testing and scale-up of PrEP could slow the Dutch gay HIV epidemicRoger Pebody | 8 years ago Phylogenetic analysis of the source of HIV infections in Dutch gay men over more than a decade show......MORE |
Xpert MTB/RIF testing has reduced MDR-TB treatment delays in South AfricaLesley Odendal | 8 years ago Although the introduction of the Xpert MTB/RIF test for TB and drug-resistant TB has improved the ......MORE |
Lessons learnt from the history of contraception are relevant for the implementation of PrEPRoger Pebody | 8 years ago Achieving a widespread and appropriate use of pre-exposure prophylaxis (PrEP) will take several yea......MORE |
One in eight children with confirmed TB have drug-resistant TB in Cape TownLesley Odendal | 8 years ago One in eight children with confirmed TB have drug-resistant TB in Cape Town, South Africa, accordin......MORE |
Malawian study provides strong evidence that HIV infection is an important risk factor for strokeMichael Carter | 8 years ago HIV infection is an important risk factor for stroke among adults in Malawi, investigators report i......MORE |
HIV salvage regimens can safely omit NRTIs, says US studyMichael Carter | 8 years ago Nucleoside reverse transcriptase inhibitors (NRTIs) can be safely omitted from HIV salvage therapy,......MORE |
DAAs could halt HCV epidemic in US – but only with near-universal testing and big increase in treatment ratesMichael Carter | 8 years ago Treatment using direct-acting agents (DAA) could have a major impact on the hepatitis C virus (HCV)......MORE |
A quarter of people with HCV initially refused access to sofosbuvir/lepidasvir, says US study, but most successfully appealMichael Carter | 8 years ago Insurers deny almost a quarter of requests for sofosbuvir/lepidasvir (Harvoni) to treat people with......MORE |
Community care workers boost TB case finding among hard-to-reach adultsLesley Odendal | 8 years ago Community care worker active case finding is an effective tool for increasing TB case detection, ac......MORE |
Previous AIDS-related pulmonary disease associated with lung cancer risk for people with HIVMichael Carter | 8 years ago AIDS-related pulmonary disease is a major factor in the increased risk of lung cancer seen in peopl......MORE |
Low implementation of Xpert MTB/RIF among HIV/TB co-infected adults in 19 low- and middle-income countriesLesley Odendal | 8 years ago Three quarters of people with HIV/TB co-infection did not receive Xpert MTB/RIF testing for TB diag......MORE |
Large UK study shows low rates of HIV testing, even among those who think they are at risk of HIVRoger Pebody | 8 years ago A major household survey of adults in the UK shows that, even among people who perceive themselves ......MORE |
Evidence for PrEP efficacy grows, but implementation presents challengesLiz Highleyman | 8 years ago Pre-exposure prophylaxis (PrEP) was a major topic at the 2015 National HIV Prevention Conference (N......MORE |
Tenofovir alafenamide fumarate at what price? No more than $1000 a year above existing tenofovir formulation, says modelMichael Carter | 8 years ago The superior safety of the tenofovir analogue tenofovir alafenamide fumarate (TAF) over tenofovir d......MORE |
Two-drug ART with dolutegravir-lamivudine would be cost-effective and achieve substantial cash savingsMichael Carter | 8 years ago Virologically suppressive first-line antiretroviral treatment with a two-drug regimen of dolutegrav......MORE |
US syringe funding ban impedes HIV and hepatitis C preventionLiz Highleyman | 8 years ago Providing sterile syringes is a proven effective way to prevent HIV and hepatitis C virus (HCV) inf......MORE |
UK maintains the largest HIV epidemic in western Europe...Gus Cairns | 8 years ago The annual surveillance report released recently by the European Centre for Disease Prevention and ......MORE |
UK maintains the largest HIV epidemic in western EuropeGus Cairns | 8 years ago The annual surveillance report released recently by the European Centre for Disease Prevention and ......MORE |
Sofosbuvir/daclatasvir combination could be produced for $200 per hepatitis C cureKeith Alcorn | 8 years ago Month-by-month tracking of the prices paid in India for the chemicals used to make hepatitis C dire......MORE |
Sofosbuvir / daclatasvir combination could be produced for $200 per hepatitis C cureKeith Alcorn | 8 years ago Month-by-month tracking of the prices paid in India for the chemicals used to make hepatitis C dire......MORE |
Drug resistance acquired during HIV PrEP rapidly disappears after medication is discontinuedMichael Carter | 8 years ago Drug resistance acquired in rare cases of HIV infection during treatment with pre-exposure prophyla......MORE |
Grazoprevir/elbasvir cures more than 90% of people with HIV/HCV co-infectionLiz Highleyman | 8 years ago Merck's grazoprevir/elbasvir combination cured 93% of people with HIV and hepatitis C co-infection,......MORE |
Death during MDR-TB treatment more likely in people with HIV and underweight or most drug-resistant patientsKeith Alcorn | 8 years ago People living with HIV, those who are underweight and those with more extensive drug resistance are......MORE |
National HIV Prevention Conference highlights progress and disparitiesLiz Highleyman | 8 years ago Pre-exposure prophylaxis (PrEP), integration of prevention and treatment services, and initiatives ......MORE |
United States faces biggest burden of hepatitis C treatment costs before 2020Keith Alcorn | 8 years ago The cost of treating hepatitis C is likely to decline dramatically over the next decade in the Unit......MORE |
New HIV cases decline in US, but population and geographic disparities persistLiz Highleyman | 8 years ago HIV diagnoses have declined by nearly 20% overall during the past decade but progress has been une......MORE |
9-month MDR-TB regimen cures 82% in African studyKeith Alcorn | 8 years ago A nine-month standardised treatment regimen for multi-drug resistant tuberculosis (MDR-TB) cured 82......MORE |
San Francisco reports progress in 'Getting to Zero' HIV prevention and treatment effortLiz Highleyman | 8 years ago San Francisco made good progress in HIV prevention and treatment during 2015, and its successes ha......MORE |
San Francisco reports progress in 'Getting to Zero' HIV prevention and treatment effortKeith Alcorn | 8 years ago San Francisco made good progress in HIV prevention and treatment during 2015, and its successes ha......MORE |
Coffee consumption linked to reduced liver fibrosis in people with HBV, HCV and NAFLDLiz Highleyman | 8 years ago Drinking coffee was associated with lower liver stiffness – a non-invasive measure used to estima......MORE |
Gay men starting to use crystal meth usually increase their sexual risk takingRoger Pebody | 8 years ago A study which followed the same group of gay men over several years has found that individuals who ......MORE |
Australian survey finds that less than a third of gay men have committed relationships with just one partnerGus Cairns | 8 years ago A large survey conducted through gay dating sites and Facebook in Australia has found that previous......MORE |
Ipergay PrEP study results publishedGus Cairns | 8 years ago The results from the Ipergay study of intermittent pre-exposure prophylaxis (PrEP) were published i......MORE |
WHO issues recommendations on linkage to care, retention, to help bring HIV treatment to allKeith Alcorn | 8 years ago The World Health Organization has issued new recommendations on how to organise services in order t......MORE |
Many more people could benefit from HIV PrEP but not enough doctors are aware, says CDCLiz Highleyman | 8 years ago One-quarter of gay and bisexual men in the US and one-fifth of people who inject drugs -- but less......MORE |
For African migrants in Europe, destitution shapes sexual behaviour and HIV riskRoger Pebody | 8 years ago For African migrants recently arrived in France, periods without a residence permit, secure housing......MORE |
Two-drug maintenance therapy keeps viral load suppressed and may even have advantages over traditional ARTMichael Carter | 8 years ago Two-drug antiretroviral therapy (ART) consisting of ritonavir-boosted atazanavir and lamivudine has......MORE |
High HCV cure rate demonstrated for people retreated after failure of short course direct-acting antiviral therapyLiz Highleyman | 8 years ago People with hepatitis C who did not achieve sustained virological response with a prior short cours......MORE |
HIV-related wasting can have long-term consequencesMichael Carter | 8 years ago HIV-associated wasting can have a long-term impact on physical function and quality of life, accord......MORE |
Dutch research identifies relationship between HIV clinic characteristics and retention of patients in careMichael Carter | 8 years ago Dutch research published in the online edition of AIDS has provided insights into the relationship ......MORE |
Triple DAA regimen cures hepatitis C patients with rapid response in just 3 weeksLiz Highleyman | 8 years ago Response-guided therapy using an all-oral regimen of three direct-acting antivirals cured a majori......MORE |
Clinical impact of effective HCV DAAs: referrals for liver transplant drop after their introductionMichael Carter | 8 years ago The number of hepatitis C virus (HCV)-related referrals for liver transplant has declined significa......MORE |
France approves PrEPGus Cairns | 8 years ago In a historic move, France has become the first country outside the USA, and the first country with......MORE |
Study reveals potential challenges for scaling up of HCV therapy in UKMichael Carter | 8 years ago A large proportion of patients with chronic hepatitis C virus (HCV) infection in the UK have co-mor......MORE |
Liver fibrosis improves after successful treatment for hepatitis CLiz Highleyman | 8 years ago A majority of people with chronic hepatitis C and advanced fibrosis or cirrhosis showed improvement......MORE |
Widely-used anti-alcoholism drug wakes up dormant HIV-infected cellsGus Cairns | 8 years ago An Australian research team has found that disulfiram, a long-established and safe drug used primar......MORE |
Daclatasvir and sofosbuvir with ribavirin cures 90% of people with genotype 3 hepatitis CLiz Highleyman | 8 years ago An all-oral combination of daclatasvir, sofosbuvir and ribavirin taken for 12 or 16 weeks led to hi......MORE |
Daclatasvir plus sofosbuvir works well for people with genotype 3 hepatitis C and advanced liver disease in real-world clinical practiceLiz Highleyman | 8 years ago Interferon-free treatment with daclatasvir plus sofosbuvir, with or without ribavirin, led to susta......MORE |
Tenofovir during pregnancy reduces risk of mother-to-child hepatitis B virus transmissionLiz Highleyman | 8 years ago Women with chronic hepatitis B and high viral load who were treated with tenofovir (Viread) during ......MORE |
UK’s latest HIV figures show the need to scale up HIV testing and preventionRoger Pebody | 8 years ago The latest annual report by Public Health England shows that, although the number of gay men who ha......MORE |
New AbbVie hepatitis C combination cures 93%-97% with genotype 3Keith Alcorn | 8 years ago A combination of two experimental direct-acting antivirals developed by AbbVie cured 93%-97% of peo......MORE |
Sofosbuvir/ledipasvir plus vedroprevir shows 96% response rate for hard-to-treat genotype 1 hepatitis C patientsLiz Highleyman | 8 years ago A triple combination of Gilead Sciences' sofosbuvir/ledipasvir (Harvoni) plus the experimental HCV......MORE |
Barcelona clinic study counts how many gay men might benefit from PrEPGus Cairns | 8 years ago A study from the Barcelona Checkpoint gay men’s HIV clinic, presented at the recent 15th European......MORE |
Sofosbuvir/velpatasvir shows high cure rates for all HCV genotypes, works well for patients with liver decompensationLiz Highleyman | 8 years ago A coformulation of sofosbuvir and the pan-genotypic HCV NS5A inhibitor velpatasvir from Gilead Scie......MORE |
Sofosbuvir & ravidasvir delivers high sustained response rates for genotype 4 hepatitis C patientsLiz Highleyman | 8 years ago A regimen of sofosbuvir and the pan-genotypic HCV NS5A inhibitor ravidasvir, with or without ribavi......MORE |
Treatment intensification with sofosbuvir permits cure after failure of previous HCV treatmentKeith Alcorn | 8 years ago Re-treating with an interferon-free regimen that previously failed to cure hepatitis C can result i......MORE |
Almost half of US Medicaid recipients denied funding for hepatitis C treatment, 4-state study showsKeith Alcorn | 8 years ago Around one in six people with hepatitis C in four US states had their prescriptions for direct-acti......MORE |
New AbbVie hepatitis C pan-genotypic combination cures 97% - 100% in early studyKeith Alcorn | 8 years ago A combination of two experimental direct-acting antivirals developed by AbbVie cured 97%-100% of no......MORE |
REP 2139 shows promise for people with hepatitis B and hepatitis delta co-infectionLiz Highleyman | 8 years ago The nucleic acid-based polymer REP 2139, used first as monotherapy then combined with pegylated int......MORE |
Liver cancer risk will remain elevated for people with cirrhosis cured of hepatitis CKeith Alcorn | 8 years ago The burden of liver cancer and cirrhosis caused by hepatitis C is likely to continue to grow in the......MORE |
Sofosbuvir/velpatasvir + GS-9857 for 8 weeks cures hepatitis C for most people with genotype 1 or 3Liz Highleyman | 8 years ago An 8-week triple combination of Gilead Sciences' sofosbuvir, velpatasvir and GS-9857 showed a high ......MORE |
HCV transmission during anal sex may happen without blood, study in HIV/HCV coinfected men findsKeith Alcorn | 8 years ago Hepatitis C virus is present in large enough quantities in the rectal fluid of men with HIV and hep......MORE |
Grazoprevir/elbasvir shows high hepatitis C cure rate for people who inject drugsLiz Highleyman | 8 years ago Merck's grazoprevir/elbasvir coformulation cured hepatitis C infection in 92% of injecting drug us......MORE |
People with HIV and HCV co-infection achieve high HCV cure rates with grazoprevir/elbasvirLiz Highleyman | 8 years ago A dual combination of Merck's grazoprevir and elbasvir taken for 12 or 16 weeks cured most HIV-posi......MORE |
Women living with HIV in the UK continue to have poorer treatment outcomesRoger Pebody | 8 years ago Women have triple the rate of poor treatment outcomes of gay men and the gap has not narrowed over ......MORE |
Ambivalence and tensions in young gay men’s accounts of monogamy and relationshipsRoger Pebody | 8 years ago Young Australian gay men’s feelings about sex and relationships are characterised by a tension be......MORE |
Low CD4 count, smoking and unhealthy alcohol use are risk factors for acute exacerbation of COPD in people with HIVMichael Carter | 8 years ago HIV infection increases the risk of acute exacerbation of chronic obstructive pulmonary disease (AE......MORE |
Truvada PrEP appears to work for transgender women, but only if used consistentlyLiz Highleyman | 8 years ago The more than 300 transgender women in the pivotal iPrEx pre-exposure prophylaxis (PrEP) trial had......MORE |
Counselling for HIV sero-discordant couples associated with reductions in HIV risk behaviourMichael Carter | 8 years ago Counselling for HIV sero-discordant couples can achieve significant reductions in sexual risk behav......MORE |
How do we maximise global HIV treatment access? IAPAC Care Continuum Guidelines make recommendationsGus Cairns | 8 years ago IAPAC, the International Association of Practitioners in AIDS Care, has issued a set of guidelines ......MORE |
Does low-level HIV viral load raise the risk of disease progression and co-morbidities?Liz Highleyman | 8 years ago People living with HIV who have a detectable but low viral load – in the range of 50 to 500 or 10......MORE |
Hormonal contraception safe for women with HIV and may have important health benefitsMichael Carter | 9 years ago HIV-positive women can safely use hormonal contraception, according to research published in the on......MORE |
Patients of non-specialist HIV physicians often have poor ART outcomes and frequently receive sub-optimal careMichael Carter | 9 years ago Physician experience is associated with the quality of care provided to HIV-positive patients, new ......MORE |
Hepatitis C incidence remains stable among gay men living with HIV in Europe, but varies across countriesLiz Highleyman | 9 years ago Researchers have seen no decline in new hepatitis C virus (HCV) infections among HIV-positive men w......MORE |
Post-treatment control of HIV appears rare, biomarkers may help predict viral reboundLiz Highleyman | 9 years ago Only four individuals out of nearly 5000 people receiving care at US military health facilities wer......MORE |
Many HIV transmissions in sero-discordant couples occuring at CD4 cell counts above ART eligibility thresholdMichael Carter | 9 years ago Many HIV transmissions in sero-discordant couples occur when the HIV-infected partner has a high CD......MORE |
Priorities for HIV care: the perspectives of healthcare providers and patientsMichael Carter | 9 years ago Virological suppression and co-morbidities are the main focus of consultations between HIV healthca......MORE |
Sofosbuvir/ledipasvir for 8 weeks cures most hard-to-treat hepatitis C patients in real-world studyLiz Highleyman | 9 years ago Most people with hepatitis C virus (HCV) in the GECCO German hepatitis C cohort who were treated wi......MORE |
Successful hepatitis C treatment lowers risk of death for people with HIV and HCV co-infectionLiz Highleyman | 9 years ago Hepatitis C treatment that leads to sustained virological response (SVR) – generally regarded as ......MORE |
Strategies for hepatitis C ‘treatment as prevention’ must address the concerns of people who inject drugsRoger Pebody | 9 years ago While epidemiologists and public health experts are excited by the potential of new hepatitis C dru......MORE |
HIV maturation inhibitor BMS-955176 shows good safety and efficacy in phase 2a trialLiz Highleyman | 9 years ago Bristol-Myers Squibb’s next-generation maturation inhibitor BMS-955176 demonstrated good antivira......MORE |
START sub-studies show no differences in lung or neurocognitive function with early or later treatmentLiz Highleyman | 9 years ago Participants who started antiretroviral therapy (ART) soon after HIV diagnosis in the large START ......MORE |
Community-based drug projects provide an alternative to compulsory detention in AsiaRoger Pebody | 9 years ago A series of pilot projects in China, Indonesia and Cambodia are showing that non-coercive, communit......MORE |
START sub-study shows more bone loss with earlier HIV treatmentLiz Highleyman | 9 years ago Participants who started antiretroviral therapy (ART) soon after HIV diagnosis in the large START t......MORE |
London clinic survey shows impact of chemsex on condom and PEP useKeith Alcorn | 9 years ago A survey of gay men in London using drugs during sex – chemsex – has shown high levels of unpro......MORE |
Risk of heart attack rises with length of HIV infection, regardless of ageKeith Alcorn | 9 years ago Ten years after becoming infected with HIV, a person living with HIV has approximately twice the ri......MORE |
Harm reduction conference calls for political leadership to reform drugs policyRoger Pebody | 9 years ago The biggest challenges to harm reduction are drugs policy and drugs laws, the Malaysian harm reduct......MORE |
Harm reduction conference calls for political leadership on drugs policy reformRoger Pebody | 9 years ago The biggest challenges to harm reduction are drugs policy and drugs laws, the Malaysian harm reduct......MORE |
With EACS release, all international HIV treatment guidelines agree on when to start – for the first time since 2006Gus Cairns | 9 years ago The new European AIDS Clinical Society (EACS) HIV clinical guidelines, released last week at the 15......MORE |
Tenofovir alafenamide single-tablet regimen shows good efficacy with improved kidney and bone safetyLiz Highleyman | 9 years ago A single-tablet regimen containing the new tenofovir alafenamide (TAF) - to be marketed as Genvoya......MORE |
When will Europe get PrEP?Keith Alcorn | 9 years ago Pressure is mounting at community level for access to pre-exposure prophylaxis (PrEP) in Europe and......MORE |
Can dolutegravir dual therapy or monotherapy produce and maintain HIV suppression?Liz Highleyman | 9 years ago The potent integrase inhibitor dolutegravir taken with a single well-tolerated NRTI was able to ful......MORE |
The majority of migrants living with HIV in Europe may have acquired HIV in their new countryGus Cairns | 9 years ago A study presented at the 15th European AIDS Conference yesterday found evidence that the majority o......MORE |
Benefits of early HIV treatment are clear, but issues raised by START and D:A:D remain unresolvedLiz Highleyman | 9 years ago The long-running controversy over when to start antiretroviral therapy (ART) has been definitively ......MORE |
Needle and syringe exchanges need to adapt to meet the needs of people who inject steroids and image-enhancing drugsRoger Pebody | 9 years ago The numbers of people injecting steroids and other image-enhancing drugs has increased significantl......MORE |
Newest MDR-TB drug prices could fall by up to 95% through generic productionKeith Alcorn | 9 years ago The cost of newer drugs for the treatment of multidrug-resistant tuberculosis (MDR-TB) could be cut......MORE |
TB death rate four times higher in Eastern Europe due to lack of HIV treatment after TB diagnosisKeith Alcorn | 9 years ago People living with HIV in Eastern Europe who develop tuberculosis (TB) are four times more likely t......MORE |
Three-month isoniazid/pyrazinamide regimen prevents TB as well as 6-month isoniazid in people living with HIVKeith Alcorn | 9 years ago A daily three-month regimen of isoniazid and pyrazinamide is just as effective at preventing the de......MORE |
Can Europe reach the 90-90-90 target for HIV treatment by 2020?Keith Alcorn | 9 years ago The European region needs to step up prevention and treatment activities if it is to reach the UNAI......MORE |
Modest bone loss seen in young men taking Truvada for pre-exposure prophylaxisLiz Highleyman | 9 years ago Young men participating in a pre-exposure prophylaxis (PrEP) demonstration project experienced mode......MORE |
Why is injecting equipment re-used? Drug users do their own research to find outRoger Pebody | 9 years ago Even in the context of the relatively good access to harm reduction services in Australia, the prin......MORE |
Peer workers improve drug users’ engagement with HIV care in UkraineRoger Pebody | 9 years ago An innovative programme in which peer outreach workers use a case management approach to help HIV-p......MORE |
One third of people with HIV in US study are not virally suppressed on antiretroviral therapyLiz Highleyman | 9 years ago A third of people with HIV on antiretroviral therapy (ART) do not have sustained viral suppression ......MORE |
How do we treat the world? Experts discuss moving to universal HIV treatmentGus Cairns | 9 years ago What practical steps does the global healthcare community need to take in order to expand HIV treat......MORE |
Sofosbuvir + daclatasvir demonstrates high cure rates for people with HIV and HCV co-infectionLiz Highleyman | 9 years ago Nearly all people with HIV and genotype 1-4 HCV co-infection treated for 12 weeks with an interfero......MORE |
Retreat of international donors and neglect of national governments threatens harm reduction servicesRoger Pebody | 9 years ago The availability of needle and syringe programmes, opioid substitution therapy and other harm reduc......MORE |
Emergency needle exchange in Indiana reduces HIV and HCV risk for people who inject drugsLiz Highleyman | 9 years ago An emergency syringe exchange program implemented after an outbreak of HIV earlier this year in the......MORE |
US study provides 'real world' evidence about which patients with hepatitis C should be prioritised for therapyMichael Carter | 9 years ago For patients with hepatitis C virus (HCV) mono-infection, baseline fibrosis stage is strongly predi......MORE |
Opioid substitution therapy, especially in combination with needle exchange, reduces transmission of hepatitis CRoger Pebody | 9 years ago A pooled analysis of 25 studies has shown for the first time good evidence that methadone and other......MORE |
Studies continued to support tenofovir alafenamide combination pill as it nears US approvalLiz Highleyman | 9 years ago A single-tablet regimen containing a new formulation of tenofovir maintained viral suppression for ......MORE |
Hepatitis C-related mortality continues to increase in the USLiz Highleyman | 9 years ago Deaths related to hepatitis C virus (HCV) infection continue to rise in the US despite the advent o......MORE |
At least 25,000 people in the US may now be using PrEPGus Cairns | 9 years ago As many as 30,000 people in the US may now be taking pre-exposure prophylaxis to prevent HIV, the f......MORE |
Abacavir/lamivudine could be driving liver damage in ART-treated patients with HIV/HCV co-infectionMichael Carter | 9 years ago Progression of liver fibrosis among ART-treated patients with HIV/HCV co-infection is associated wi......MORE |
HIV attachment inhibitor BMS-663068 matches atazanavir in phase 2b studyLiz Highleyman | 9 years ago Bristol-Myers Squibb’s HIV attachment inhibitor BMS-663068 (fostemsavir), which prevents the viru......MORE |
Interferon-free treatment works well for people who inject drugs, but barriers to access remainLiz Highleyman | 9 years ago Hepatitis C treatment for people who inject drugs, including those receiving opioid substitution th......MORE |
Affordable Care Act coverage improves chances of viral suppression for Americans with HIVLiz Highleyman | 9 years ago Enrolling low-income and under-insured people with HIV in one of the new Affordable Care Act (ACA)......MORE |
No transmission of integrase inhibitor-resistant HIV seen in California patientsGus Cairns | 9 years ago Not one case of transmission of HIV that is resistant to any of the integrase inhibitor (INI) drugs......MORE |
People who inject drugs should have access to hepatitis C treatment, expert panel recommendsKeith Alcorn | 9 years ago New recommendations on hepatitis C treatment and care for people who inject drugs encourage physici......MORE |
People with HIV are at higher risk of several types of cancer, large study findsLiz Highleyman | 9 years ago People living with HIV remain at risk of AIDS-defining cancers in the era of effective antiretrovir......MORE |
New antiretrovirals and HIV treatment strategies highlighted at ICAACLiz Highleyman | 9 years ago Researchers presented findings from several HIV studies at the 55th Interscience Conference on Ant......MORE |
US HIV physicians routinely offering early ART but only a third have prescribed PrEPMichael Carter | 9 years ago Most doctors at the frontline of the HIV epidemic in the United States recommend early antiretrovir......MORE |
Recent infection and ART treatment interruptions are key periods for HIV transmissionMichael Carter | 9 years ago A large proportion of HIV transmissions occur during recent infection or antiretroviral treatment i......MORE |
New HCV NS5A inhibitor EDP-239 looks good in early studies, more evidence supports early hepatitis C treatmentLiz Highleyman | 9 years ago A new hepatitis C virus (HCV) NS5A inhibitor being developed by Enanta – EDP-239 – was well-tol......MORE |
PrEP preferences in gay men are predicted by the frequency and predictability of the sex they haveGus Cairns | 9 years ago A recently-published survey from the US and Canada reveals that on the whole HIV-negative gay men w......MORE |
WHO guidelines recommend universal antiretroviral treatment, PrEP for those at substantial riskLiz Highleyman | 9 years ago The World Health Organization (WHO) released updated guidelines today calling for antiretroviral th......MORE |
The enduring power of stigma – understanding why HIV-positive gay men don’t disclose their statusRoger Pebody | 9 years ago The accounts of a group of gay men living with HIV in Dublin, most of whom rarely, if ever, disclos......MORE |
High standards of care associated with reduced mortality risk of patients with HIVMichael Carter | 9 years ago Quality of care (QOC) in the first twelve months after entering HIV care is associated with longer-......MORE |
High standards of care associated with reduced mortality risk of patients with HIVMichael Carter | 9 years ago Quality of care (QOC) in the first twelve months after entering HIV care is associated with longer-......MORE |
Second UK cost-effectiveness study finds that large PrEP programmes may need drug price cut to be affordableGus Cairns | 9 years ago A second UK cost-effectiveness study of pre-exposure prophylaxis has concluded that a medium-sized ......MORE |
Substantial improvement in life expectancy of older HIV-positive patients in modern treatment era, report DanesMichael Carter | 9 years ago The prognosis of older HIV-positive patients has improved substantially during the era of combinati......MORE |
Increasing levels of engagement with care is key to controlling HIV epidemic in USMichael Carter | 9 years ago “Test-and-treat” is unlikely to be an effective strategy to control the HIV epidemic in the Uni......MORE |
Awareness of treatment’s impact on transmission is transforming the lives of couples of mixed HIV statusRoger Pebody | 9 years ago A greater understanding of the impact of HIV treatment on prevention is changing the experience of ......MORE |
Sexual transmission of HCV is increasing among gay and bisexual men with HIV, meta-analysis findsLiz Highleyman | 9 years ago Sexual transmission of hepatitis C virus (HCV) is occurring among HIV-positive men who have sex wit......MORE |
Thai testing campaign suggests how local cultures can influence testing behaviourGus Cairns | 9 years ago A campaign to encourage Thai gay men and other men who have sex with men (MSM) to test at least onc......MORE |
Spanish pharmacy HIV testing programme detects many new infectionsGus Cairns | 9 years ago A programme in which cheap, 30-minute HIV tests were offered in local pharmacy shops in three Spani......MORE |
Cost of comprehensive global viral hepatitis prevention and treatment effort might peak at $11 billion in 2025Keith Alcorn | 9 years ago Reaching the World Health Organization’s (WHO) proposed targets for viral hepatitis control by 20......MORE |
PROUD PrEP study results publishedGus Cairns | 9 years ago The results of the PROUD study of HIV pre-exposure prophylaxis (PrEP) using daily tenofovir + emtri......MORE |
Bone loss slows, but continues long-term in HIV-positive people on antiretroviral therapyLiz Highleyman | 9 years ago People with HIV experienced a decrease in bone density at the hip and spine during their first two ......MORE |
Asymptomatic neurocognitive impairment in people with HIV does predict later neurocognitive symptomsLiz Highleyman | 9 years ago People with HIV who showed evidence of asymptomatic neurocognitive impairment at study entry were n......MORE |
Rilpivirine + darunavir HIV maintenance regimen matches standard three-drug antiretroviral therapyLiz Highleyman | 9 years ago An NRTI-sparing dual antiretroviral regimen consisting of the NNRTI rilpivirine (Edurant) plus the ......MORE |
US PrEP care cascade analysis suggests that major, structural barriers need to be addressed for PrEP to have an impactRoger Pebody | 9 years ago The uptake of PrEP in people who need it risks being limited due to low levels of awareness, gaps i......MORE |
Medicines Patent Pool looks at hepatitis CKeith Alcorn | 9 years ago Greg Perry, Executive Director of the Medicines Patent Pool, told delegates at the World Hepatitis ......MORE |
Oestrogen may block HIV reactivation, hints at gender differences in viral reservoirsLiz Highleyman | 9 years ago Oestrogen receptors on cells may play a role in HIV latency and reactivation, and drugs targeting t......MORE |
Half of American gay men using dating apps have interacted with a PrEP userRoger Pebody | 9 years ago Almost half of American gay men recruited to a survey via advertising on a major mobile phone datin......MORE |
‘Undetectable’ is both a milestone and an identity for gay men recently diagnosed with HIVRoger Pebody | 9 years ago Achieving an undetectable viral load is a key milestone in the period after diagnosis with HIV, qua......MORE |
World Health Organization calls for ambitious global targets for viral hepatitis controlKeith Alcorn | 9 years ago The World Health Organization (WHO) is calling for ambitious new global targets for diagnosis, trea......MORE |
No HIV infections seen in San Francisco PrEP users referred via primary careGus Cairns | 9 years ago A programme that provides pre-exposure prophylaxis (PrEP) through primary care referrals in San Fra......MORE |
STI clinic attendees have high HIV diagnosis rates in Netherlands, but many missed opportunities in primary careGus Cairns | 9 years ago Two studies from the Netherlands show that while the proportion of people with HIV who are diagnose......MORE |
HIV treatment as prevention scale-up linked to reduced mortality among people who inject drugs in VancouverLiz Highleyman | 9 years ago HIV-related and all-cause death decreased significantly among people who inject drugs – with sim......MORE |
HIV-positive youth are less likely than adults to achieve viral suppression on antiretroviral treatmentLiz Highleyman | 9 years ago While adolescents and young adults are about as likely as older people to be linked to care after b......MORE |
Fatty liver may contribute to higher risk of death for HIV/HCV co-infected peopleLiz Highleyman | 9 years ago About a quarter of people in a New York City cohort who had HIV and hepatitis C virus (HCV) died ov......MORE |
Good outcomes for people living with HIV diagnosed with Hodgkin's lymphoma in FranceMichael Carter | 9 years ago People living with HIV who are diagnosed with Hodgkin’s lymphoma now have excellent outcomes, Fre......MORE |
HCV infection associated with hardening of the coronary arteryMichael Carter | 9 years ago Chronic hepatitis C virus (HCV) infection is associated with an important early warning side of car......MORE |
HIV-treatment 'booster drugs' are most likely to have dangerous interactions with methamphetamine, mephedrone, MDMA and ketamineRoger Pebody | 9 years ago The two drugs involved in HIV treatment that are most likely to have dangerous interactions with re......MORE |
Ugandan gay men talk about why they do not always use condomsGus Cairns | 9 years ago Gay men and other men who have sex with men (MSM) in Uganda, who had not used a condom last time th......MORE |
HIV-positive postpartum women who rapidly re-engage with HIV care more likely to have viral suppression in longer termMichael Carter | 9 years ago HIV-positive women who have recently given birth have low rates of engagement with HIV care, invest......MORE |
Low rates of engagement with HIV care among women who have recently given birth in Cape Town townshipsMichael Carter | 9 years ago Only half of HIV-positive mothers in townships near Cape Town, South Africa, who received antenatal......MORE |
People with HIV and hepatitis B co-infection can safely switch to simpler TAF single-tablet regimenLiz Highleyman | 9 years ago People with HIV and hepatitis B virus (HBV) co-infection maintained HIV viral suppression, maintain......MORE |
Hepatitis C cure associated with significant improvement in liver stiffness in people with HIV and HCV co-infectionMichael Carter | 9 years ago A successful response to hepatitis C virus (HCV) therapy is associated with a significant improveme......MORE |
People with hepatitis B can safely use Truvada PrEP for HIV preventionLiz Highleyman | 9 years ago People with hepatitis B virus (HBV) infection did not experience liver inflammation 'flares' or oth......MORE |
Study sheds light on how tenofovir is processed in different body tissuesLiz Highleyman | 9 years ago Tenofovir, which is widely used for HIV treatment and prevention, is activated in a tissue-specific......MORE |
Third of people with HIV who use drugs intentionally miss doses of HIV treatment when planning to use drugsMichael Carter | 9 years ago Beliefs about possible toxic interactions between antiretroviral therapy (ART) and illicit drugs ar......MORE |
Low-threshold methadone maintenance reduces HIV risk for people who inject drugsKeith Alcorn | 9 years ago Receiving methadone maintenance therapy through primary care physicians or community pharmacies sig......MORE |
First Brazilian PrEP data reinforce evidence that PrEP is most used by those at greatest riskGus Cairns | 9 years ago The first data from a Brazilian open-label demonstration project of HIV pre-exposure prophylaxis (P......MORE |
Cirrhosis and decompensation are common among people with chronic hepatitis CLiz Highleyman | 9 years ago More than one-quarter of people with chronic hepatitis C at Kaiser-Permanente developed liver cirrh......MORE |
Indiana HIV outbreak offers lessons about containing local outbreaks and need for harm reductionLiz Highleyman | 9 years ago An early-2015 outbreak of HIV and hepatitis C virus (HCV) in rural Indiana, USA, linked to injectio......MORE |
Starting ART reduces TB risk for HIV-positive patients in South AfricaMichael Carter | 9 years ago Starting antiretroviral therapy (ART) significantly reduces the risk of tuberculosis (TB) for patie......MORE |
WAVES shows elvitegravir regimen beats boosted atazanavir for women with HIVLiz Highleyman | 9 years ago A study of antiretroviral treatment specifically for women with HIV showed that a single-tablet reg......MORE |
Open-label PrEP in Botswana: very high adherence and no HIV infections seenGus Cairns | 9 years ago A study of open-label Truvada HIV pre-exposure prophylaxis (PrEP) in Botswana among heterosexual pe......MORE |
Peer or community interventions improve outcomes for mothers with HIVCarole Leach-Lemens | 9 years ago Peer- and community-based interventions can significantly increase retention in care of mothers wit......MORE |
Retention in pre-ART care can be boosted by monthly visits from volunteer support workersMichael Carter | 9 years ago Retention in HIV care for patients not eligible for antiretroviral therapy (ART) can be boosted by ......MORE |
Daclatasvir plus sofosbuvir cures HCV for most people with HIV and HCV co-infection in French compassionate use programmeLiz Highleyman | 9 years ago Interferon-free treatment using daclatasvir (Daklinza) and sofosbuvir (Sovaldi), with or without ri......MORE |
Interferon-free hepatitis treatment is highly effective for people with HIV and HCV co-infection in three studiesLiz Highleyman | 9 years ago Three different interferon-free regimens – sofosbuvir/ledipasvir, AbbVie's 3D regimen and grazopr......MORE |
Intensification of antiretroviral therapy reduces risk of late-term mother-to-child HIV transmissionCarole Leach-Lemens | 9 years ago Maternal and infant antiretroviral therapy (ART) intensification is very effective in preventing HI......MORE |
Implant and injectable hormonal contraception most effective methods for women living with HIVCarole Leach-Lemens | 9 years ago Hormonal contraceptive methods are highly effective in reducing the risk of pregnancy in women livi......MORE |
Liver fibrosis regression after hepatitis C treatment linked to reduced complications and death in people with HIV and HCV co-infectionLiz Highleyman | 9 years ago People with HIV and HCV co-infection, with liver cirrhosis, who achieve sustained virological respo......MORE |
Switching to new tenofovir alafenamide keeps virus in check and improves kidney and bone healthLiz Highleyman | 9 years ago People who switch from the current version of tenofovir to tenofovir alafenamide (TAF) – a new fo......MORE |
Raltegravir appears to prevent mother-to-child HIV transmission during late pregnancyLiz Highleyman | 9 years ago Combination antiretroviral therapy containing the integrase inhibitor raltegravir (Isentress) appea......MORE |
PrEP demo project finds the people at highest HIV risk generally take PrEP most consistentlyGus Cairns | 9 years ago An open-label demonstration project of Truvada pre-exposure prophylaxis (PrEP) in the United States......MORE |
Vancouver's treatment as prevention success is also due to harm reduction and addiction treatmentRoger Pebody | 9 years ago “We talk a lot about the success of treatment as prevention in Vancouver, but we always need to m......MORE |
HIV self-testing may help the 'hard to reach' learn their status, but uncertainties remainRoger Pebody | 9 years ago HIV self-testing (or ‘home testing’) is likely to have an important place in future global HIV ......MORE |
Peer-led network intervention substantially lowers HIV infections in people who use drugs in UkraineRoger Pebody | 9 years ago A cluster randomised trial in Ukraine has shown that a peer education project reduced new HIV infec......MORE |
Gay youth PrEP study finds good retention and reasonable adherenceGus Cairns | 9 years ago A US study of pre-exposure prophylaxis in 200 young gay and bisexual men aged 18-22 found reasonabl......MORE |
Giving people information about HIV treatment as prevention lessens stigma and increases testing ratesRoger Pebody | 9 years ago A large randomised trial of communities in rural Malawi shows that a single community meeting provi......MORE |
New NNRTI doravirine suppresses HIV as well as efavirenz but with fewer central nervous system side-effectsLiz Highleyman | 9 years ago Merck's next-generation NNRTI doravirine (formerly known as MK-1439) was found to be as effective ......MORE |
Same-day start to antiretroviral treatment leads to faster HIV suppression in San FranciscoLiz Highleyman | 9 years ago A programme at San Francisco General Hospital that offers antiretroviral therapy (ART) on the same......MORE |
Opioid substitution therapy combined with HIV treatment saves the lives of more drug users than ART aloneKeith Alcorn | 9 years ago Providing opioid substitution therapy (OST) alongside antiretroviral therapy (ART) to people who in......MORE |
Younger gay men have much lower risk of acquiring HIV than previous generations, but racial disparities persistRoger Pebody | 9 years ago An innovative analysis of HIV trends in the Seattle area has found that gay men who were born in th......MORE |
Half of African migrants diagnosed with HIV in France acquired HIV while living thereRoger Pebody | 9 years ago Between a third and a half of African people living with HIV in France probably acquired HIV after ......MORE |
Next-generation maturation inhibitor BMS-955176 shows good antiviral activity in combination with atazanavirLiz Highleyman | 9 years ago The next-generation HIV maturation inhibitor BMS-955176 was well-tolerated and suppressed HIV viral......MORE |
Intermittent PrEP may be a robust strategy for anal sex – vaginal much less certainGus Cairns | 9 years ago The pharmacodynamics (drug absorption and elimination rates) of the two drugs that comprise Truvada......MORE |
‘Nuanced’ sero-adaptive behaviours being used by Australian and American gay menRoger Pebody | 9 years ago There is evidence that some groups of Australian and American gay men are considering HIV-positive ......MORE |
'Nuanced' sero-adaptive behaviours being used by Australian and American gay menRoger Pebody | 9 years ago There is evidence that some groups of Australian and American gay men are considering HIV-positive ......MORE |
Treatment cascades show 90-90-90 goal within reach for some - but Eastern Europe lags behind AfricaKeith Alcorn | 9 years ago Global analysis of HIV treatment cascades – the proportions of people diagnosed with HIV, in care......MORE |
Treatment cascades show 90-90-90 goal within reach for some – but Eastern Europe lags behind AfricaKeith Alcorn | 9 years ago Global analysis of HIV treatment cascades – the proportions of people diagnosed with HIV, in care......MORE |
The Pros and Cons of PrEP: trial volunteers recount their experience of the ADAPT studyGus Cairns | 9 years ago The reasons whether or not people come forward for pre-exposure prophylaxis (PrEP) or take it once ......MORE |
Cash compensation encourages uptake of circumcision, PMTCT servicesKeith Alcorn | 9 years ago Cash compensation can improve the uptake of key HIV prevention services in sub-Saharan Africa, res......MORE |
Active invitation and tracing more likely to get men involved in couples HIV counselling and testingCarole Leach-Lemens | 9 years ago Active invitation and tracing of male partners of pregnant women newly diagnosed with HIV substanti......MORE |
Cash to stay in school doesn’t reduce HIV incidence in South African study – but school attendance protected young women against HIVKeith Alcorn | 9 years ago A conditional cash transfer to the households of adolescent girls to promote school attendance did ......MORE |
START trial provides definitive evidence of the benefits of early HIV treatmentLiz Highleyman | 9 years ago People who start antiretroviral therapy (ART) immediately after HIV diagnosis, while their CD4 cell......MORE |
Innovative approaches to linkage to care boost clinic visits, HIV treatment uptake in African studyKeith Alcorn | 9 years ago A systematic effort to promote HIV testing, linkage to care for people diagnosed with HIV and circu......MORE |
Non-daily PrEP regimens provide extra options, but adherence is often better with daily dosingRoger Pebody | 9 years ago For some people in some settings, less frequent PrEP regimens with doses linked to sexual activity ......MORE |
Targets proliferate in HIV cure researchGus Cairns | 9 years ago The Towards an HIV Cure two-day symposium has become a fixture in advance of the International AIDS......MORE |
No HIV infections from partners with fully suppressed viral load during long-term follow up of landmark treatment as prevention trialKeith Alcorn | 9 years ago Final follow up of the HPTN 052 study of treatment as prevention shows no evidence of HIV transmiss......MORE |
Young woman stays undetectable for twelve years off treatment after early HIV therapyGus Cairns | 9 years ago The 8th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 20......MORE |
Presumptive treatment of TB in advanced HIV no better than giving ART and isoniazidKeith Alcorn | 9 years ago Giving treatment for tuberculosis to all people with very advanced HIV disease at the time they sta......MORE |
Access to screening and treatment are key issues for hepatitis B and C and HIV/viral hepatitis co-infectionLiz Highleyman | 9 years ago The development of effective new interferon-free treatment makes it possible to cure more than 90% ......MORE |
Vancouver Consensus statement calls for early access to treatment and PrEP worldwideKeith Alcorn | 9 years ago Leading figures in the HIV response have endorsed a call for immediate access to antiretroviral the......MORE |
World Health Organization urges more HIV testing by non-medical staff, outside of clinical settings, targeted to those who need it the mostRoger Pebody | 9 years ago In addition to recommending that routine HIV testing in medical settings be expanded to reach new g......MORE |
World Health Organization to recommend HIV treatment for allKeith Alcorn | 9 years ago The World Health Organization will issue new HIV treatment guidelines later this year recommending ......MORE |
Test and treat studies and African countries showing that 90-90-90 targets are achievableRoger Pebody | 9 years ago Health services in some African countries including Botswana, Rwanda and Malawi are now providing e......MORE |
Reaching UNAIDS HIV treatment targets could avert millions of deaths and new infectionsLiz Highleyman | 9 years ago Achieving UNAIDS 90-90-90 targets for getting more people with HIV diagnosed and on antiretroviral ......MORE |
New drug holds out promise of long-term control or even cure of HIVGus Cairns | 9 years ago Scientists at the Scripps Research Institute in California have discovered a new type of drug that ......MORE |
HIV PEP with emtricitabine/tenofovir/rilpivirine has excellent completion and adherence ratesMichael Carter | 9 years ago Daily post-exposure prophylaxis (PEP) with single tablet emtricitabine/tenofovir/rilpivirine (Compl......MORE |
HIV-positive patients in Africa do well on three second-line ART regimensMichael Carter | 9 years ago Three second-line antiretroviral therapy (ART) regimens are equally safe and effective for patients......MORE |
South Africa: Women of lower socio-economic status have greater needs for services to prevent mother-to-child HIV transmissionLesley Odendal | 9 years ago Pregnant women of lower socio-economic status are more likely to take up early HIV testing and to h......MORE |
One step further towards an HIV vaccine: and this one performed as expectedGus Cairns | 9 years ago A recent experimental HIV vaccine protected 50% of a group of twelve rhesus monkeys from infection ......MORE |
Second-line ART patients reach viral re-suppression following intensified adherence supportLesley Odendal | 9 years ago Sixty-seven per cent of all patients who were failing second-line ART achieved viral re-suppressio......MORE |
Black market for Truvada PrEP may undermine treatment adherence in marginalised people living with HIVRoger Pebody | 9 years ago The increasing demand for pre-exposure prophylaxis (PrEP) is likely to increase the likelihood that......MORE |
Community-based adherence clubs show high retention in HIV care and treatment adherenceLesley Odendal | 9 years ago People with HIV who were receiving their HIV treatment outside of health facilities in community-ba......MORE |
Nurse-led palliative care can be successfully integrated into routine HIV services in KenyaMichael Carter | 9 years ago Integrating nurse-led palliative care into routine HIV services has positive effects for the psycho......MORE |
Prompt ART especially important for people with HIV aged 45 and overMichael Carter | 9 years ago Delaying antiretroviral therapy (ART) may have especially serious consequences for middle-aged and ......MORE |
Longer secondary education protects against HIV infection, Botswana study showsKeith Alcorn | 9 years ago Every additional year of schooling among young people in Botswana was associated with an 8% reducti......MORE |
Where next in PrEP and microbicides? Europeans discuss research pipelineGus Cairns | 9 years ago Thursday 18 June saw the final research meeting in Brussels of CHAARM (Combined Highly Active Anti-......MORE |
ART roll-out in Uganda accompanied by increased rates of HIV disclosure to spousesMichael Carter | 9 years ago Roll-out of antiretroviral treatment (ART) has been accompanied by an increase in the proportion of......MORE |
Multiple strategies for safer conception need to incorporate couples' preferencesLesley Odendal | 9 years ago Misunderstandings about serodiscordance and limited understanding of female fertility and male inse......MORE |
Unmet basic needs may be related to poor rates of durable viral suppression among transgender women with HIVMichael Carter | 9 years ago Transgender women living with HIV are less likely to have excellent adherence to antiretroviral tre......MORE |
People with HIV and HCV co-infection who have fibrosis stages F2 and above should be prioritised for new anti-HCV therapiesMichael Carter | 9 years ago People with HIV and hepatitis C virus (HCV) co-infection who have advanced liver fibrosis should be......MORE |
South Africa: Lower coverage of maternal HIV testing among adolescents leading to higher mother-to-child transmissionLesley Odendal | 9 years ago Adolescents have lower coverage of HIV testing and subsequent prevention of mother-to-child (PMTCT)......MORE |
South Africa: Lower coverage of maternal HIV testing among adoelscents leading to higher mother-to-child transmissionKeith Alcorn | 9 years ago Adolescents have lower coverage of HIV testing and subsequent prevention of mother-to-child (PMTCT)......MORE |
HIV stigma decreases with scale-up of HIV treatmentRoger Pebody | 9 years ago In high-prevalence countries of sub-Saharan Africa, the scale-up of HIV treatment appears to have r......MORE |
Liver transplants in HIV/HCV co-infection: study underlines importance of hepatitis C treatmentKeith Alcorn | 9 years ago People with HIV and hepatitis C co-infection were significantly more likely to experience organ re......MORE |
New British guidelines recommend treatment for everyone with HIVKeith Alcorn | 9 years ago Everyone with HIV who is prepared to take antiretroviral treatment should receive it, regardless of......MORE |
Four in ten people diagnosed with HIV in Europe are migrantsGus Cairns | 9 years ago Nearly four out of every ten people with HIV in the European Economic Area (EEA) is a migrant to th......MORE |
Not having enough food linked to poor treatment outcomes in New YorkRoger Pebody | 9 years ago People who don’t have enough food to eat are less likely to have an undetectable viral load than ......MORE |
Living in a stigmatizing country increases HIV risk for MSM in EuropeMichael Carter | 9 years ago Men who have sex with men (MSM) living in European countries with laws and attitudes that stigmatiz......MORE |
Vaginal microbicide ring study releases first data on participantsGus Cairns | 9 years ago An efficacy study of a new method of HIV prevention has published its first data. ASPIRE is one of ......MORE |
Liver function and survival improve after treatment with Viekirax + Exviera regimenLiz Highleyman | 9 years ago Hepatitis C patients treated with AbbVie's Viekirax plus Exviera or '3D' regimen saw improvements i......MORE |
Geriatric conditions common in middle-aged and older HIV-positive menMichael Carter | 9 years ago Geriatric conditions were common in middle-aged and older HIV-positive adults in a San Francisco cl......MORE |
Geriatric HIV: living with multiple medical conditions will become the norm as population agesRoger Pebody | 9 years ago In fifteen years time, the clinical needs of Dutch people living with HIV will have changed substan......MORE |
Consider cannabis use when assessing middle-aged and older patients with HIV, say US investigatorsMichael Carter | 9 years ago Recent cannabis (marijuana) use by middle-aged HIV-positive adults is associated with poor mental h......MORE |
High HCV infection rate in sub-Saharan Africa, with prevalence especially high in patients with HIVMichael Carter | 9 years ago Prevalence of hepatitis C virus (HCV) infection is high in sub-Saharan Africa, according to a repor......MORE |
Acute HCV infections observed among HIV-negative gay men in LondonMichael Carter | 9 years ago Hepatitis C virus (HCV) infections are occurring among HIV-negative gay men in London, investigator......MORE |
Most gay men with HIV in central European capitals are undiagnosed, survey has foundGus Cairns | 9 years ago A survey of gay men in the European cities of Barcelona, Bratislava, Bucharest, Ljubljana, Prague a......MORE |
Hepatitis B and C co-infection linked to worse liver fibrosis than hepatitis B aloneLiz Highleyman | 9 years ago People with both hepatitis B virus (HBV) and hepatitis C virus (HCV) co-infection may experience mo......MORE |
Hepatitis C treatment could halve HCV transmission among gay men in UK over 10 yearsKeith Alcorn | 9 years ago Access to more effective hepatitis C treatment could halve new infections among men who have sex wi......MORE |
Reinfection after hepatitis C cure: prevention may require long-term support for people who have injected drugsKeith Alcorn | 9 years ago Reinfection rates after hepatitis C cure among people who inject drug users, as well as past drug u......MORE |
Sofosbuvir plus daclatasvir for 12 weeks cures most HIV/HCV coinfected patientsLiz Highleyman | 9 years ago Nearly all HIV/HCV coinfected patients treated for 12 weeks with an interferon- and ribavirin-free ......MORE |
Transmitted HIV drug resistance is persistent but is not harming treatment responses in the UKGus Cairns | 9 years ago A study that looks at the genetic makeup of archived samples of drug-resistant HIV in the UK has fo......MORE |
Depression strongly associated with risky sex in UK gay menRoger Pebody | 9 years ago HIV-negative gay men who have several symptoms of depression are more likely to report sex without ......MORE |
Provision of PrEP in the UK will be cost-effective for gay men at high risk of HIV, model findsGus Cairns | 9 years ago A cost-effectiveness model of HIV pre-exposure prophylaxis (PrEP) for gay men based on the data fro......MORE |
Many South African women become infected with HIV during pregnancy posing high risk of transmission to their infantsMichael Carter | 9 years ago There is a high risk of HIV seroconversion during pregnancy for women in South Africa, investigator......MORE |
Harm reduction for people who inject drugs in New York has worked, but hasn’t reduced racial inequalityGus Cairns | 9 years ago Needle and syringe exchange and opiate substitution therapy in New York City has worked in reducing......MORE |
START trial finds that early treatment improves outcomes for people with HIVGus Cairns | 9 years ago A major international randomised clinical trial has found that people living with HIV have a consid......MORE |
High lifetime costs of treating HIV show importance of investing in preventionMichael Carter | 9 years ago The lifetime cost for treating one HIV infection in the UK is almost £380,000, according to a mode......MORE |
Acute HIV infection may present in many ways – sometimes as a serious illnessGus Cairns | 9 years ago A Swiss study of people who were diagnosed during early HIV infection has found that a quarter of t......MORE |
Funders' priorities and targets hindered community mobilisation and meaningful participation of sex workers in IndiaRoger Pebody | 9 years ago Two qualitative studies, investigating the implementation of a massive programme of HIV prevention ......MORE |
Lower daily tenofovir dose of 150mg safe and effective in people with moderate renal impairmentMichael Carter | 9 years ago A reduced tenofovir (Viread) dose of 150mg daily appears to be a safe and effective treatment for p......MORE |
Hepatitis C treatment for people in prison may be highly cost-effective in EnglandKeith Alcorn | 9 years ago Reducing the duration of direct-acting antiviral treatment for hepatitis C will make treatment for ......MORE |
Prioritisation is crucial for the success of PrEP, model confirmsGus Cairns | 9 years ago A mathematical model developed by two researchers at Imperial College in London, and based on what ......MORE |
Statin use associated with lower risk of liver decompensation and death in hepatitis C patients with cirrhosisLiz Highleyman | 9 years ago Hepatitis C patients with liver cirrhosis were significantly less likely to progress to decompensat......MORE |
Inter-connecting health problems increase HIV risk for MSMMichael Carter | 9 years ago Intertwining health problems – syndemics - are associated with higher viral load and poorer adh......MORE |
Civacir immune globulin may help prevent HCV reinfection after liver transplantLiz Highleyman | 9 years ago Civacir, a hepatitis C immune globulin or antibody product, reduced the likelihood of hepatitis C v......MORE |
Gilead triple combination cures easy-to-treat hepatitis C patients in 6 weeks, but 4 weeks is not enoughLiz Highleyman | 9 years ago A 6-week regimen of sofosbuvir (Sovaldi) plus two experimental direct-acting antivirals being devel......MORE |
Shortening hepatitis C treatment to 6 weeks effective but not perfect for easier-to-treat patientsKeith Alcorn | 9 years ago Shortening hepatitis C treatment to 6 weeks for easier-to-treat patients without cirrhosis does not......MORE |
Truvada PrEP causes only mild loss of bone mineral densityMichael Carter | 9 years ago Treatment with tenofovir/emtricitabine (Truvada) as pre-exposure prophylaxis (PrEP) is associated w......MORE |
People with hepatitis C have higher cancer rates, even when excluding liver cancerLiz Highleyman | 9 years ago Hepatitis C patients in the Kaiser Permanente Southern California health maintenance organization h......MORE |
Modern NNRTI regimens can be effective with 85% adherenceMichael Carter | 9 years ago Some modern HIV treatment regimens can achieve viral suppression with adherence rates as low as 85%......MORE |
Modern NNRTI regimens can be effective with 85% adherenceMichael Carter | 9 years ago Some modern HIV treatment regimens can achieve viral suppression with adherence rates as low as 85%......MORE |
Sofosbuvir-based therapy effective for hepatitis C patients with decompensated cirrhosisLiz Highleyman | 9 years ago Interferon-free regimens containing sofosbuvir (Sovaldi) plus simeprevir (Olysio) cured about three......MORE |
Five antiretroviral combinations associated with increased risk of a cardiovascular eventMichael Carter | 9 years ago Treatment with four individual and five combinations of anti-HIV drugs is associated with an increa......MORE |
Gilead triple combination cures easy-to-treat hepatitis C patients in 6 weeks, but 4 weeks is not enoughLiz Highleyman | 9 years ago A 6-week regimen of sofosbuvir (Sovaldi) plus two experimental direct-acting antivirals being devel......MORE |
HIV infection and low CD4 count associated with hardening of arteriesMichael Carter | 9 years ago HIV infection is associated with an increased risk of hardening of the arteries, investigators repo......MORE |
Another study confirms detrimental effects of delaying hepatitis C treatmentLiz Highleyman | 9 years ago Deferring antiviral therapy for hepatitis C until a person progresses to advanced liver disease has......MORE |
When a short course of sofosbuvir/ledipasvir fails, some people can be cured of hepatitis C with a double treatment durationLiz Highleyman | 9 years ago More than 70% of people with chronic genotype 1 hepatitis C who did not achieve a sustained virolog......MORE |
People who don’t tell anyone else their HIV status have as good health outcomes as other people living with HIVRoger Pebody | 9 years ago A large survey of people attending HIV clinics in the UK has found that those individuals who chose......MORE |
Many undiagnosed HIV infections picked up when testing people who have other medical conditions, but implementation challenges remainRoger Pebody | 9 years ago A Europe-wide project offering HIV tests to hospital patients with glandular fever symptoms, swolle......MORE |
Sofosbuvir-based treatment safe and effective in advanced kidney diseaseKeith Alcorn | 9 years ago Sofosbuvir-based direct-acting antiviral therapy for hepatitis C can be used safely and effectively......MORE |
Merck's grazoprevir/elbasvir combo cures 99% of hepatitis C in chronic kidney diseaseKeith Alcorn | 9 years ago The once-daily combination of grazoprevir and elbasvir cured hepatitis C in 99% of people with adva......MORE |
Sofosbuvir plus pegylated interferon/ribavirin is highly effective for people with hard-to-treat genotype 3 hepatitis CLiz Highleyman | 9 years ago A throwback regimen of sofosbuvir (Sovaldi), ribavirin and pegylated interferon taken for 12 weeks ......MORE |
Sofosbuvir, daclatasvir and ribavirin cures hepatitis C for most people with advanced cirrhosis or liver transplantsLiz Highleyman | 9 years ago An interferon-free regimen of sofosbuvir, daclatasvir and ribavirin for 12 weeks produced sustained......MORE |
New EASL guidelines prioritise interferon-free hepatitis C treatmentLiz Highleyman | 9 years ago The European Association for the Study of the Liver (EASL) released its latest hepatitis C treatmen......MORE |
Alcohol misuse the strongest predictor of severe liver damage and death in French people with hepatitis CKeith Alcorn | 9 years ago People with hepatitis C have a much greater risk of liver-related hospitalisation or death if they ......MORE |
Expanded vaccination and treatment could help eliminate hepatitis B worldwideLiz Highleyman | 9 years ago While universal infant hepatitis B virus (HBV) vaccination has already led to major advances in red......MORE |
Grazoprevir/elbasvir highly effective in treatment-experienced a nd HIV-coinfected hepatitis C patientsKeith Alcorn | 9 years ago The combination of grazoprevir and elbasvir without ribavirin is highly effective in curing hepati......MORE |
Advanced liver damage is common in people with undiagnosed hepatitis C in US surveyKeith Alcorn | 9 years ago Around one in five of people with hepatitis C in the United States who do not know of their inf......MORE |
Grazoprevir/elbasvir highly effective in treatment-experienced and HIV-coinfected hepatitis C patientsKeith Alcorn | 9 years ago The combination of grazoprevir and elbasvir without ribavirin is highly effective in curing hepatit......MORE |
First HIV home test approved for sale in UKRoger Pebody | 9 years ago The BioSure HIV Self Test, designed to be used by untrained users at home was granted a CE mark yes......MORE |
Many people living with HIV willing to take part in cure research, despite its risksRoger Pebody | 9 years ago There is a strong interest among people living with HIV in studies towards an HIV cure, with many p......MORE |
Grazoprevir / elbasvir highly effective in previously untreated hepatitis CKeith Alcorn | 9 years ago A 12-week course of the combination of grazoprevir and elbasvir cured 95% of previously untreated p......MORE |
Men taking HIV treatment have undetectable viral loads in the rectum; sexually transmitted infections make no differenceRoger Pebody | 9 years ago A small study assessing the infectiousness of HIV-positive gay men taking antiretroviral therapy ha......MORE |
Sofosbuvir/ledipasvir plus ribavirin shows high cure rate for hepatitis C patients with advanced liver diseaseLiz Highleyman | 9 years ago An oral regimen of sofosbuvir/ledipasvir (Harvoni) and ribavirin taken for 12 or 24 weeks produced ......MORE |
Merck HCV combination effective after failure of first generation of direct-acting antiviralsKeith Alcorn | 9 years ago A 12-week course of treatment with two direct-acting antivirals in development by Merck plus riba......MORE |
Merck HCV combination achieves 90% cure in advanced cirrhosisKeith Alcorn | 9 years ago A 12-week course of treatment with two direct-acting antivirals in development by Merck cured hepat......MORE |
Treatment outcomes no better with single tablet regimens than individual tabletsRoger Pebody | 9 years ago One pill a day HIV treatments such as Atripla, Stribild and Eviplera have the same rates of virolog......MORE |
HCV viral load levels during treatment and speed of decline do not predict cure with interferon-free therapyLiz Highleyman | 9 years ago Direct-acting antiviral regimens containing sofosbuvir (Sovaldi) and the drugs in Viekirax/Exviera ......MORE |
Daily PrEP leads to better adherence and protective drug levels in womenLiz Highleyman | 9 years ago HIV-negative African women assigned to take once-daily Truvada for HIV pre-exposure prophylaxis (Pr......MORE |
High treatment failure rate among Thai children switching to second-line ARTMichael Carter | 9 years ago There is a high treatment failure rate among children taking second-line antiretroviral therapy (AR......MORE |
Annual CD4 count monitoring may be sufficient for people doing well on HIV treatmentMichael Carter | 9 years ago Annual CD4 count monitoring may be sufficient for people taking antiretroviral treatment who have a......MORE |
Newly adopted risk behaviours predict HIV infections in Portuguese gay menRoger Pebody | 9 years ago Changes to an individual’s risk profile – including starting to have unprotected sex with a ste......MORE |
High-dose rifampicin may shorten time to TB clearanceLiz Highleyman | 9 years ago A combination regimen containing high-dose rifampicin (also known as rifampin) was associated with ......MORE |
Women in PrEP trial feared they would have to leave study if they reported low adherenceGus Cairns | 9 years ago Post-study interviews and computer questionnaires conducted with former participants in a trial of ......MORE |
Opioid substitution treatment increases chances that people who inject drugs will have good adherence to HIV therapyMichael Carter | 9 years ago Opioid substitution treatment (OST) increases the chances of people who inject drugs achieving good......MORE |
Global hepatitis B epidemic treatable at cost of just $36 per patient per yearMichael Carter | 9 years ago Large-scale production of generic entecavir could cut the cost of first-line hepatitis B virus (HBV......MORE |
Six in ten US HIV infections are transmitted by people who know they have HIV but are not in careGus Cairns | 9 years ago The majority of HIV in the USA is transmitted by people who know they have HIV but are not in care,......MORE |
End-stage liver disease is a concern for people with HIV and hepatitis B or C co-infectionLiz Highleyman | 9 years ago People with HIV and hepatitis B or C virus co-infection are more likely to progress to end-stage li......MORE |
Ritonavir concentrations not correlated with lipid levels in people with HIV taking boosted atazanavir or boosted darunavirMichael Carter | 9 years ago People taking HIV treatment based on ritonavir-boosted atazanavir and darunavir have comparable lon......MORE |
Cannabis use reduces risk of insulin resistance in people with HIV/HCV co-infectionMichael Carter | 9 years ago Cannabis use is associated with a reduced risk of insulin resistance in people with HIV and hepatit......MORE |
Chinese study sheds light on how well treatment may work as prevention in the real worldGus Cairns | 9 years ago A study from the Henan province of China published recently shows that antiretroviral therapy (ART)......MORE |
HCV sexual transmission linked to anal sex, drug use, lower CD4 countLiz Highleyman | 9 years ago In addition to the usual risk factors for hepatitis C virus (HCV) sexual transmission seen in most ......MORE |
Most HIV-positive gay men in European survey are on HIV treatment, though fewer in the eastGus Cairns | 9 years ago The large EMIS survey of gay men living in Europe has found that over 70% of respondents with HIV a......MORE |
More people in the UK are starting HIV treatment early, in order to reduce their risk of transmissionRoger Pebody | 9 years ago There is evidence of increasing interest in HIV treatment as prevention among people living with HI......MORE |
Adherence support improves ART outcomes in KenyaMichael Carter | 9 years ago The scale-up of antiretroviral therapy (ART) in Kenya is being undermined by high rates of treatmen......MORE |
Early antiretroviral treatment reduces, but does not eliminate HIV reservoirLiz Highleyman | 9 years ago Starting antiretroviral therapy (ART) very soon after infection may limit the size of the HIV 'rese......MORE |
Experimental agents reverse HIV latency and help immune system fight HIV-infected cellsLiz Highleyman | 9 years ago Researchers at the recent Conference on Retroviruses and Opportunistic Infections (CROI 2015) in S......MORE |
Screening for cryptococcal meningitis and adherence support reduce mortality among people starting ART in AfricaMichael Carter | 9 years ago Screening and treatment for cryptococcal meningitis combined with a short period of adherence suppo......MORE |
Good mental health associated with excellent adherence among people taking ART for preventionMichael Carter | 9 years ago Good mental health was the only significant factor associated with optimal pill-taking among people......MORE |
Canada: PrEP use now could save considerable sums in the futureGus Cairns | 9 years ago A Canadian paper that weighs the cost of using pre-exposure prophylaxis (PrEP) to prevent HIV infec......MORE |
Cabotegravir and rilpivirine effective for HIV maintenance therapy at 96 weeksLiz Highleyman | 9 years ago An combination of two once-daily oral antiretrovirals – the next-generation integrase inhibitor c......MORE |
FRAX fracture prediction tool underestimates fracture risk in people with HIVTheo Smart | 9 years ago The Fracture Risk Assessment Tool (FRAX), an online tool developed by the World Health Organization......MORE |
Sustained virological response represents a long-term cure for people with hepatitis C treated with sofosbuvirLiz Highleyman | 9 years ago Almost all patients with hepatitis C virus alone or HIV/HCV coinfection who achieved sustained viro......MORE |
Inflammation and gut leakage remains elevated in people with HIV despite early antiretroviral treatmentLiz Highleyman | 9 years ago Inflammatory changes and damage to the gut begin very soon after initial HIV infection, and may not......MORE |
Screening may miss pre-cancerous anal lesions in women with HIVTheo Smart | 9 years ago Existing algorithms to screen for anal cancer in women living with HIV could be missing many cases ......MORE |
Re-infection due to ongoing risk probably the cause of HCV recurrence after SVRMichael Carter | 9 years ago Rates of hepatitis C virus (HCV) reoccurrence after successful therapy differ markedly between risk......MORE |
Sofosbuvir/ledipasvir raises some antiretroviral levels in HIV/HCV coinfected peopleKeith Alcorn | 9 years ago HIV/HCV coinfected people who take sofosbuvir/ledipasvir (Harvoni) to treat hepatitis C along with ......MORE |
Sofosbuvir/ledipasvir raises some antiretroviral levels in HIV/HCV coinfected peopleLiz Highleyman | 9 years ago HIV/HCV coinfected people who take sofosbuvir/ledipasvir (Harvoni) to treat hepatitis C along with ......MORE |
Studies offer mounting evidence that statins may reduce the risk of heart disease in people living with HIVTheo Smart | 9 years ago Evidence is mounting that statin therapy can prevent the progression of coronary atherosclerosis (......MORE |
We may need to combine many approaches to achieve a cure, delegates hearGus Cairns | 9 years ago It is unlikely that one single approach will achieve a cure for HIV infection, delegates at a commu......MORE |
Does HIV make you fat? Study connects viral load with fat gainsGus Cairns | 9 years ago HIV infection or inflammatory changes associated with it may be responsible for fat accumulation an......MORE |
Screening study finds high prevalence of early-stage lung cancer among smokers with HIVTheo Smart | 9 years ago Using low-dose computed tomography to screen selected people living with HIV who smoke, led to ear......MORE |
Smoking is the biggest risk factor for non-AIDS-defining cancers in people living with HIVTheo Smart | 9 years ago Smoking appears to contribute most to the burden of non-AIDS-defining cancers diagnosed in people l......MORE |
Varenicline helps people with HIV stop smoking, but success rate remains lowLiz Highleyman | 9 years ago The smoking cessation drug varenicline (Champix, or Chantix in the United States) helped more peopl......MORE |
HIV attachment inhibitor BMS-663068 safe and effective in phase 2b studyLiz Highleyman | 9 years ago Bristol-Myers Squibb's BMS-663068 or fostemsavir, a first-in-class HIV attachment inhibitor that s......MORE |
Deferring hepatitis C treatment can lead to liver cancer and death, despite cureLiz Highleyman | 9 years ago HIV/HCV coinfected people who delay hepatitis C treatment remain at risk for liver failure, hepatoc......MORE |
Progression to severe fibrosis or cirrhosis is common among baby boomers with hepatitis C in the USLiz Highleyman | 9 years ago The burden of hepatitis C virus (HCV) infection is high in the US, with a substantial number of in......MORE |
Study finds high rates of cancer among older people living with HIVTheo Smart | 9 years ago Older people living with HIV (over the age of 65) are at greatly increased risk of HIV-associated c......MORE |
Levels of maraviroc in vaginal and rectal tissues may not be high enough for pre-exposure prophylaxisLiz Highleyman | 9 years ago Levels of the HIV entry inhibitor maraviroc (Celsentri/Selzentry) in vaginal and rectal tissues did......MORE |
Financial incentives did not improve linkage to care or viral suppression in US studyGus Cairns | 9 years ago A US study which offered patients gift cards to present themselves for care after testing, and also......MORE |
Tenofovir, boosted atazanavir and boosted lopinavir are associated with cumulative risk of developing chronic kidney diseaseGus Cairns | 9 years ago Three antiretroviral drugs are associated with a slowly increasing rate of chronic kidney disease o......MORE |
Two interferon-free regimens show high HCV cure rates for people with HIV and HCV co-infectionLiz Highleyman | 9 years ago A pair of two-drug, 12-week regimens containing neither interferon nor ribavirin – sofosbuvir (So......MORE |
Tenofovir alafenamide equally effective but safer for kidneys and bones than current formulationLiz Highleyman | 9 years ago Tenofovir alafenamide (TAF), a new formulation that has lower concentrations in the blood but reach......MORE |
Treatment cascades and viral load surveys show how African countries can maximise prevention benefits of HIV treatmentKeith Alcorn | 9 years ago Reaching ambitious HIV prevention targets in South Africa will require intensified efforts to engag......MORE |
Circumcision is reducing HIV incidence in Uganda, Rakai community study showsKeith Alcorn | 9 years ago The growing uptake of medical male circumcision by men in the Rakai district of Uganda is leading ......MORE |
No HIV transmissions from HIV-positive partner seen in Australian gay couples studyGus Cairns | 9 years ago An Australian-based study of gay male couples of opposite HIV status (serodifferent couples) has so......MORE |
US PEPFAR abstinence and faithfulness funding had no impact on sexual behaviour in AfricaKeith Alcorn | 9 years ago Nearly US$1.3 billion spent on US-funded programmes to promote abstinence and faithfulness in sub-S......MORE |
HIV maturation inhibitor BMS-955176 looks promising in early studyLiz Highleyman | 9 years ago A second-generation HIV maturation inhibitor, BMS-955176, demonstrated good safety and high potency......MORE |
Starting HIV treatment at CD4 count above 500 reduces the risk of serious illness and death by 44%, African Temprano trial showsKeith Alcorn | 9 years ago Starting HIV treatment at a CD4 cell count above 500 reduced the risk of serious illness including ......MORE |
Combining PrEP and ART could almost eliminate HIV infection, east African study findsGus Cairns | 9 years ago Giving both pre-exposure prophylaxis (PrEP) and antiretroviral therapy (ART) to heterosexual couple......MORE |
XDR-TB in South Africa is largely spread person-to-person, not by failure of drug treatmentKeith Alcorn | 9 years ago The vast majority of people with extensively drug-resistant tuberculosis (XDR-TB) diagnosed in the......MORE |
Stopping cotrimoxazole during antiretroviral therapy raises risk of bacterial illness, malaria, Ugandan trial showsKeith Alcorn | 9 years ago Stopping cotrimoxazole prophylaxis increases the risk of serious bacterial infections and malaria, ......MORE |
Week-on, weekend-off treatment controls viral load in young peopleKeith Alcorn | 9 years ago Taking an efavirenz-based antiretroviral regimen during the week and taking no medication on two da......MORE |
PrEP use rising in San Francisco, but scaling up could further cut new infectionsLiz Highleyman | 9 years ago Use of Truvada (tenofovir/emtricitabine) pre-exposure prophylaxis, better known as PrEP, is increas......MORE |
Disappointing result for tenofovir-gel microbicide shows that young women still lack HIV prevention methods they can useGus Cairns | 9 years ago Among some highly promising results from HIV prevention studies presented at the Conference on Retr......MORE |
7-country study shows triple-drug combination superior for preventing infant HIV infectionKeith Alcorn | 9 years ago Implementing the World Health Organization (WHO) recommendation of three-drug antiretroviral treatm......MORE |
Breastfeeding mothers often undiagnosed in sub-Saharan AfricaKeith Alcorn | 9 years ago A large proportion of women in sub-Saharan Africa who are at high risk of transmitting HIV to their......MORE |
Pre-exposure prophylaxis also stops 86% of HIV infections in Ipergay studyGus Cairns | 9 years ago A French and Canadian study of pre-exposure prophylaxis (PrEP) presented today at the Conference on......MORE |
Pre-exposure prophylaxis (PrEP) stops 86% of HIV infections in PROUD studyGus Cairns | 9 years ago A study of pre-exposure prophylaxis (PrEP), the English PROUD study, demonstrated the highest effec......MORE |
Local spending on HIV prevention in England plunges to 70p per person, per yearRoger Pebody | 9 years ago HIV prevention in England is underfunded and deprioritised, says the National AIDS Trust (NAT). Whe......MORE |
Low CD4 count important risk factor for oral HPV infection in patients with HIVMichael Carter | 9 years ago A low CD4 count is the single most important risk factor for oral human papillomavirus (HPV) infect......MORE |
Clinicians report two acute HCV infections in Kaiser San Francisco PrEP programmeLiz Highleyman | 9 years ago Two HIV-negative men gay receiving HIV pre-exposure prophylaxis (PrEP) through Kaiser Permanente in......MORE |
HIV testing continues to rise in UK gay men, but safer sex knowledge dropsRoger Pebody | 9 years ago With health services and HIV prevention organisations now having relentlessly focused on HIV testin......MORE |
Researchers may have caught HIV becoming more virulentGus Cairns | 9 years ago A study from Cuba has generated wide media interest because researchers have identified a particula......MORE |
Early antiretroviral treatment reduces seizure risk by two-thirds for children with HIVMichael Carter | 9 years ago Early antiretroviral therapy prevents the development of epilepsy in children with HIV, results of ......MORE |
Patients with HIV can safely receive kidneys from deceased HIV-positive donors, with good five-year survival ratesMichael Carter | 9 years ago HIV-positive patients can safely receive kidneys from deceased HIV-infected donors, investigators f......MORE |
Pilot study suggests that PrEP for other STIs might workGus Cairns | 9 years ago A small pilot study using a daily dose of the antibiotic doxycycline as pre-exposure prophylaxis (P......MORE |
A more personalised approach to hepatitis C treatment may improve adherence and completion ratesRoger Pebody | 9 years ago People receiving treatment for hepatitis C value clinicians who give information and clinical feedb......MORE |
VOICE trial: Microbicide gel may have stopped two out of three HIV infections – in the women who used itGus Cairns | 9 years ago The final published paper on the VOICE trial in women in three African countries mainly reinforces ......MORE |
Men who have sex with men have other health inequalities as well as poor sexual health, say Public Health EnglandRoger Pebody | 9 years ago The UK government’s leading body for public health this week launched a new framework for improvi......MORE |
No improvements in CD4 count at diagnosis in African patients in last decadeGus Cairns | 9 years ago A study by Harvard Medical School has found that the average CD4 count in sub-Saharan African peopl......MORE |
Screening for bone fracture risk should be routine for over-40s with HIV, new guidelines recommendKeith Alcorn | 9 years ago Screening for fracture risk should be a routine part of HIV care for all over-40s, and all postmeno......MORE |
AbbVie next-generation hepatitis C drugs look promising in early studiesLiz Highleyman | 9 years ago AbbVie's investigational HCV protease inhibitor ABT-493 and NS5A inhibitor ABT-530 demonstrated go......MORE |
African American people’s AIDS conspiracy beliefs best understood in terms of social anxiety and distrust, not ignoranceRoger Pebody | 9 years ago The idea that AIDS was created as part of a government-led conspiracy to decimate the African Ameri......MORE |
Smoking is the main cause of increased risk of heart attack in people with HIVRoger Pebody | 9 years ago People living with HIV who smoke have an almost three-fold greater risk of heart attack than HIV-ne......MORE |
Starting HIV treatment early and then interrupting is no better than delaying itGus Cairns | 9 years ago A French study that looked at the total amount of time since infection that people with HIV have sp......MORE |
Many HIV-positive people’s understanding of the law on HIV transmission is “weak and patchy”Roger Pebody | 9 years ago Many people living with HIV in England have a limited understanding of the law which leaves them ei......MORE |
Substance use and social problems predict HIV infection in American gay menRoger Pebody | 9 years ago American gay men reporting depression, childhood sexual abuse, stimulant use, other substance use a......MORE |
Successful peer-recruited project shows it is possible to do prevention work with gay men in hostile environmentsGus Cairns | 9 years ago A community education and HIV prevention project that took place among 626 gay men and other men......MORE |
Improved school attendance credited with reducing HIV infections among teenage girls in UgandaRoger Pebody | 9 years ago The Ugandan government’s decision to abolish tuition fees for school pupils, the resulting improv......MORE |
HCV prevention campaigns need to focus on reducing frequency of injecting drug use involving sharing of equipmentMichael Carter | 9 years ago Sharing injecting equipment is associated with a low per-event probability of hepatitis C virus (HC......MORE |
Gay men are better at predicting when they won’t have sex than when they willGus Cairns | 9 years ago A study in which a group of HIV-negative gay and bisexual men from New York were asked to predict e......MORE |
Elite controllers may pay a high price for their low viral loadGus Cairns | 9 years ago About one in 200 people with HIV maintains an undetectable viral load and high CD4 counts without h......MORE |
Experimental siRNA therapy lowers HBsAg levels in people with hepatitis BLiz Highleyman | 9 years ago ARC-520, a novel therapy using short interfering RNA, appeared safe and was associated with a reduc......MORE |
US guidelines on prevention with people living with HIV now emphasise engagement with care, HIV treatment and social factorsRoger Pebody | 9 years ago The American public health agency, the Centers for Disease Control and Prevention (CDC) has publish......MORE |
Entecavir and tenofovir work well for people with drug-resistant hepatitis B virusLiz Highleyman | 9 years ago A combination of entecavir plus tenofovir effectively suppressed hepatitis B virus (HBV) in people ......MORE |
CDC researchers publish estimate of effectiveness of condom use in anal sexGus Cairns | 9 years ago A paper this month in the Journal of Acquired Immune Deficiency Syndromes finally makes publicly av......MORE |
ART during tuberculosis therapy reduces mortality risk for people with HIVMichael Carter | 9 years ago There is a high mortality rate among people living with HIV undergoing treatment for tuberculosis (......MORE |
One million people with hepatitis C in the US at high priority for treatmentLiz Highleyman | 9 years ago An estimated 813,000 people with diagnosed hepatitis C in the US have undergone liver disease stagi......MORE |
Many hepatitis C patients with cirrhosis or advanced fibrosis face liver failure and liver cancerLiz Highleyman | 9 years ago Nearly one-third of chronic hepatitis C patients with liver cirrhosis and 12% with advanced fibrosi......MORE |
Strategies to improve male partner involvement in microbicide research neededLesley Odendal | 9 years ago Vaginal microbicides were partially developed in response to power differentials within sexual rel......MORE |
UK government halves the budget of HIV prevention programme for EnglandRoger Pebody | 9 years ago The Department of Health’s funding for HIV Prevention England, the national HIV prevention progra......MORE |
Smoking doubles risk of death for patients taking HIV therapyMichael Carter | 9 years ago Smoking doubles the mortality risk for people with HIV taking antiretroviral therapy, a study publi......MORE |
No new HIV infections seen among Kaiser PrEP usersLiz Highleyman | 9 years ago No new HIV infections have occurred among more than 500 users of the Kaiser Permanente healthcare p......MORE |
HIV most often passed on by younger gay men who have undiagnosed HIV, are not on treatment, and have an ongoing partnershipRoger Pebody | 9 years ago A modelling study based on the UK’s HIV epidemic among gay men estimates that two-thirds of infec......MORE |
HIV has become more virulent over time, not less, European study findsGus Cairns | 9 years ago The largest cohort study ever to look at CD4 count and viral loads in HIV-positive people around th......MORE |
Sofosbuvir/ledipasvir cures most previously treated hepatitis C patients with cirrhosisLiz Highleyman | 9 years ago Difficult-to-treat hepatitis C patients with liver cirrhosis who were not cured with a prior course......MORE |
Poor weight gain during first year of ART associated with increased mortality risk for children with HIV in resource-limited settingsMichael Carter | 9 years ago Poor weight gain after starting antiretroviral therapy (ART) is associated with increased mortality......MORE |
European HIV response "falling behind" as Eastern European epidemic growsKeith Alcorn | 9 years ago HIV diagnoses have increased by 80% in the European region since 2004, and three quarters of new HI......MORE |
Reduced physical function significantly increases mortality risk of middle-aged people living with HIVMichael Carter | 9 years ago HIV infection is associated with reduced physical performance, investigators report in the online e......MORE |
Safer injecting practices would be better promoted by focusing on pleasure and practical concerns – not the risk of infectionRoger Pebody | 9 years ago Harm reduction interventions often fail to engage people who inject drugs because they over-emphasi......MORE |
Sofosbuvir/ledipasvir with ribavirin cures most people with hepatitis C recurrence after liver transplantationLiz Highleyman | 9 years ago An interferon-free regimen of sofosbuvir plus ledipasvir (Harvoni) taken with ribavirin for 12 or 2......MORE |
Sofosbuvir + simeprevir shows good results for hepatitis C in real-world useLiz Highleyman | 9 years ago Regimens containing sofosbuvir (Sovaldi) – including sofosbuvir plus simeprevir (Olysio) – work......MORE |
HIV epidemic will spring back without near-universal diagnosis and treatment, says UNAIDSGus Cairns | 9 years ago “Without scale-up, the AIDS epidemic will continue to outrun the response, increasing the long-te......MORE |
British HIV cure survey: most respondents would be prepared to take some health risk to help find a cure for HIVGus Cairns | 9 years ago An online survey that asked people living with HIV, largely from the UK, whether they would partici......MORE |
DAAs show good cure rates and liver function improvement for transplant recipients with recurrent HCVLiz Highleyman | 9 years ago Several presentations at the American Association for the Study of Liver Diseases (AASLD) Liver Mee......MORE |
AbbVie 3D regimen cures recurrent HCV in most liver transplant recipients without cirrhosisLiz Highleyman | 9 years ago AbbVie's 3D regimen (newly named Viekirax + Exviera) demonstrated a sustained virological response ......MORE |
NHS urgently needs to make PrEP available, say HIV prevention organisationsRoger Pebody | 9 years ago A group of community organisations working on HIV prevention have called for the NHS to speed up it......MORE |
Tenofovir continues to suppresses hepatitis B virus for eight yearsLiz Highleyman | 9 years ago Most people with chronic hepatitis B who are treated with tenofovir for eight years continued to ma......MORE |
Tenofovir continues to suppress hepatitis B virus for eight yearsLiz Highleyman | 9 years ago Most people with chronic hepatitis B who are treated with tenofovir for eight years continued to ma......MORE |
Daclatasvir + sofosbuvir demonstrates good cure rate for genotype 3 hepatitis CLiz Highleyman | 9 years ago An all-oral combination of daclatasvir (Daklinza) plus sofosbuvir (Sovaldi), taken for 12 weeks, pr......MORE |
Positive response to 'gift tokens for undetectable viral load' trialGus Cairns | 9 years ago A US study presented at last month’s HIV Research for Prevention conference found generally posit......MORE |
AbbVie 3D regimen and sofosbuvir/ribavirin show high cure rates for HCV in people with HIV co-infectionLiz Highleyman | 9 years ago AbbVie's 3D regimen (paritaprevir/ombitasvir/ritonavir plus dasabuvir) with ribavirin for 12 weeks ......MORE |
Sofosbuvir + GS-5816 for 12 weeks shows high HCV cure rates, but 8 weeks is less effective for some patientsLiz Highleyman | 9 years ago A 12-week oral combination of sofosbuvir plus the experimental NS5A inhibitor GS-5816 demonstra......MORE |
HIV in the UK: 76% diagnosed, 90% on treatment, 90% undetectableRoger Pebody | 9 years ago The UK’s annual epidemiological report, released yesterday, shows that the country already provid......MORE |
Adding pegylated interferon to tenofovir improves odds of HBsAg loss in hepatitis B patientsLiz Highleyman | 9 years ago People with chronic hepatitis B virus (HBV) infection are more likely to experience favourable trea......MORE |
Gay men in UK recommended to receive HPV vaccinationMichael Carter | 9 years ago HPV vaccination programmes should be extended to gay and other men who have sex with men (MSM), an ......MORE |
Merck's grazoprevir/elbasvir combo shows high cure rates, including for people with cirrhosis and HIV/HCV co-infectionLiz Highleyman | 9 years ago An all-oral regimen of grazoprevir (MK-5172) and elbasvir (MK-8742), taken with or without ribaviri......MORE |
Groundbreaking HIV vaccine's effects were real – and could be made to work betterGus Cairns | 9 years ago Findings from further studies using a reformulation of the only HIV vaccine that has ever worked in......MORE |
Sofosbuvir/ledipasvir and AbbVie 3D regimen cure most people with HCV genotype 4Liz Highleyman | 9 years ago Sofosbuvir/ledipasvir without ribavirin and AbbVie's 3D regimen (paritaprevir/ombitasvir plus dasab......MORE |
Restoring and maintaining a high CD4 count possible for vast majority of people living with HIV in FranceAlain Volny-Anne | 9 years ago A large French study has shown that the vast majority of people living with HIV who started treatme......MORE |
Sofosbuvir/ledipasvir with ribavirin is highly effective for people with decompensated cirrhosisLiz Highleyman | 9 years ago An oral regimen of sofosbuvir/ledipasvir plus ribavirin taken for 12 weeks cured most hepatitis C p......MORE |
People living with HIV have high survival rates after liver transplants due to HCCLiz Highleyman | 9 years ago People with HIV – most of whom had hepatitis B or C co-infection – generally had good outcomes ......MORE |
What are the barriers that could stop HIV treatment becoming HIV prevention?Gus Cairns | 9 years ago One of the key strategies involved in trying to bring an end to the HIV epidemic is to increase the......MORE |
Hepatitis B testing and treatment rates are low among U.S. veteransLiz Highleyman | 9 years ago Only 15% of US veterans have been tested for hepatitis B virus (HBV) infection, and among those who......MORE |
Hepatitis B testing and treatment rates are low among US veteransLiz Highleyman | 9 years ago Only 15% of US veterans have been tested for hepatitis B virus (HBV) infection, and among those who......MORE |
Daclatasvir TRIO regimen has good cure rates for hepatitis C patients with or without cirrhosisLiz Highleyman | 9 years ago A 12-week all-oral regimen of daclatasvir, asunaprevir and beclabuvir, with or without ribavirin, c......MORE |
Young drug injectors on opioid maintenance therapy have lower risk of hepatitis C infectionLiz Highleyman | 9 years ago Young people who inject drugs (PWID) who undergo opioid agonist maintenance therapy with methadone ......MORE |
Misunderstanding of questions regarding anal sex in microbicide HIV prevention trialLesley Odendal | 9 years ago There was widespread misunderstanding and misinterpretation of questions about anal sex being asked......MORE |
Once-daily dolutegravir superior to darunavir/ritonavir in 96-week follow-upAlain Volny-Anne | 9 years ago Treatment with a triple antiretroviral combination containing once-daily integrase inhibitor dolute......MORE |
Doravirine works as well as efavirenz with fewer CNS side-effectsLiz Highleyman | 9 years ago Once-daily doravirine (MK-1439), an experimental NNRTI, demonstrated viral suppression similar to ......MORE |
Sofosbuvir/ledipasvir cures nearly all genotype 1 HCV for people with HIV co-infectionLiz Highleyman | 9 years ago All but one participant treated for hepatitis C virus (HCV) with a co-formulation of sofosbuvir an......MORE |
Sustained virological response to hepatitis C treatment reduces mortality, liver cancer and liver transplantsLiz Highleyman | 9 years ago People who achieve sustained virological response (SVR) when treated with interferon-based therapy ......MORE |
Sofosbuvir/ledipasvir cures nearly all genotype 1 HIV/HCV coinfected patientsLiz Highleyman | 9 years ago All but one participant treated with a co-formulation of sofosbuvir and ledipasvir (Harvoni) achiev......MORE |
Protease inhibitor monotherapy: darunavir/ritonavir less effective than three-drug therapyKeith Alcorn | 10 years ago Darunavir/ritonavir monotherapy results in a lower rate of viral suppression after 48 weeks when co......MORE |
Truvada PrEP use rising in United States, especially among menLiz Highleyman | 10 years ago The number of people using Truvada for pre-exposure prophylaxis (PrEP) in the US is increasing and ......MORE |
One third of TB cases in Eastern European HIV clinic survey multi-drug resistantAlain Volny-Anne | 10 years ago Around one-third of people living with HIV in Eastern Europe who were diagnosed with tuberculosis (......MORE |
Australia performs best in HIV treatment cascade – 62% with undetectable viral loadKeith Alcorn | 10 years ago Australia and northern European countries are doing far better than North America at retaining peop......MORE |
Australia performs best in HIV treatment cascade - 62% with undetectable viral loadKeith Alcorn | 10 years ago Australia and northern European countries are doing far better than North America at retaining peop......MORE |
Generic antiretrovirals could save NHS £1.25 billion over 5 years, study findsMichael Carter | 10 years ago Switching all patients taking antiretrovirals in the United Kingdom to generic versions of the drug......MORE |
Efavirenz compromises hormonal contraceptive implantKeith Alcorn | 10 years ago The widely-prescribed non-nucleoside reverse transcriptase inhibitor substantially reduces levels ......MORE |
Do emtricitabine and lamivudine have similar virological efficacy when used in first-line HIV therapy?Michael Carter | 10 years ago First-line antiretroviral regimens containing emtricitabine have superior virological efficacy to c......MORE |
HIV testing and ongoing relationships are part of 'safer sex' for young gay menRoger Pebody | 10 years ago Many young gay men consider ‘safer sex’ to be about more than condom use, according to a qualit......MORE |
Injectable rilpivirine shows promise in phase I trials – but may work better for anal than vaginal sexGus Cairns | 10 years ago A phase one dose-finding and safety study in humans of TMC278 LA, a long-acting, injectable formati......MORE |
Tenofovir gel use associated with lower HSV-2 risk in womenLesley Odendal | 10 years ago The risk of acquiring herpes simplex virus type 2 (HSV-2) was reduced by 46% (aIRR:0.54, 95%CI:0.30......MORE |
Injectable cabotegravir makes progress towards human efficacy studies: doubts about injectable rilpivirineGus Cairns | 10 years ago Researchers have determined the dose of an injectable formulation of the integrase inhibitor cabote......MORE |
Increased expenditure on social security has benefits for TB control in the EUMichael Carter | 10 years ago Increased expenditure on social protection programmes – sickness, disability and unemployment ben......MORE |
Research for Prevention conference opens with real hope for an HIV vaccineGus Cairns | 10 years ago “There’s only one Berlin patient still. But by this time next year he will at least be joined b......MORE |
Second European PrEP study is closed early due to high effectivenessGus Cairns | 10 years ago In an extraordinary development, a second European scientific trial of pre-exposure prophylaxis (Pr......MORE |
Second European PrEP study closes placebo arm early due to high effectivenessGus Cairns | 10 years ago In an extraordinary development, a second European scientific trial of pre-exposure prophylaxis (Pr......MORE |
How does a ‘human rights based approach’ work out on the ground? Lessons from South AfricaRoger Pebody | 10 years ago While international rhetoric on HIV and AIDS frequently invokes human rights, putting these ideas i......MORE |
Emerging epidemic of transmitted HIV drug resistance in low- and middle-income countries, with highest burden seen in MSMMichael Carter | 10 years ago Prevalence of transmitted drug-resistant HIV has doubled in low- and middle-income countries in rec......MORE |
Bedaquiline as part of tailored therapy for MDR- and XDR-TB achieves impressive culture conversion ratesMichael Carter | 10 years ago Use of the new anti-tuberculosis (TB) drug bedaquiline as part of a tailored regimen achieved high ......MORE |
AbbVie 3D HCV regimen well-tolerated in PEARL trialsLiz Highleyman | 10 years ago AbbVie's 3D hepatitis C regimen containing paritaprevir (ABT-450), ombitasvir, and dasabuvir was ge......MORE |
HIV care cascade at Kaiser Permanente varies by sex and ageTheo Smart | 10 years ago Though there has been improving performance of healthcare delivery at each point of the HIV care ca......MORE |
Behavioural and financial incentives may improve HIV treatment outcomesTheo Smart | 10 years ago While making medications free can remove barriers to access for individuals who cannot pay for trea......MORE |
NNRTIs and protease inhibitors both good for first ART, channelling affects choicesLiz Highleyman | 10 years ago Non-nucleoside reverse transcriptase inhibitors (NNRTIs) and boosted protease inhibitors work equ......MORE |
Infants in southern Africa start antiretroviral therapy late with advanced diseaseLesley Odendal | 10 years ago Three quarters of infants starting antiretroviral therapy (ART) across eleven clinics in southern A......MORE |
No to treating our way out of the epidemic, say South African expertsKeith Alcorn | 10 years ago No, we cannot treat our way out of the HIV epidemic, was the resounding sentiment of a panel of exp......MORE |
No to treating our way out of the epidemic, say South African expertsLesley Odendal | 10 years ago No, we cannot treat our way out of the HIV epidemic, was the resounding sentiment of a panel of exp......MORE |
Sofosbuvir/ledipasvir safe and effective for genotype 1 HCVLiz Highleyman | 10 years ago A single-tablet regimen containing the hepatitis C virus (HCV) nucleotide polymerase inhibitor so......MORE |
Inflammatory markers associated with development of diabetes in people taking HIV therapyMichael Carter | 10 years ago Low-level elevations in important markers of systemic inflammation are associated with the developm......MORE |
High effectiveness seen in English PrEP trialGus Cairns | 10 years ago The Steering Committee* of the PROUD trial of pre-exposure prophylaxis (PrEP) in gay men in England......MORE |
Targeted adherence measures and viral load monitoring needed to improve retention in South African ART programmeLesley Odendal | 10 years ago 57% of people living with HIV in South Africa who are eligible to initiate antiretroviral therapy (......MORE |
HIV stigma starts young, but can be corrected, African schoolchildren's study showsGus Cairns | 10 years ago A study conducted among nearly 40,000 school students aged 12 to 14 in nine southern African countr......MORE |
Care programme improves clinic attendance and rates of virologic suppression among vulnerable HIV-positive patients in New YorkMichael Carter | 10 years ago Enrollment in a comprehensive care coordination programme significantly improves levels of engageme......MORE |
HCV core-antigen testing is a reliable way of detecting acute HCV infections in HIV-positive gay menMichael Carter | 10 years ago Hepatitis C virus (HCV) core-antigen testing is a highly reliable way of diagnosing acute HCV infec......MORE |
HIV treatment roll-out has had only a modest impact on mortality in Lusaka, ZambiaMichael Carter | 10 years ago The scale-up of antiretroviral therapy (ART) programmes in Lusaka, Zambia, has been accompanied by ......MORE |
HIV-related stigma has increased in Uganda despite treatment roll-outMichael Carter | 10 years ago HIV continues to be stigmatised despite increased access to antiretroviral therapy (ART), according......MORE |
Counselling during routine HIV care reduces rates of risky sex among people on ART in South AfricaMichael Carter | 10 years ago HIV prevention counselling delivered during routine care reduces sexual risk behaviour in people re......MORE |
The treatment cascade in the United States – good in Ryan White programmes, but overall picture for gay men is poorMichael Carter | 10 years ago People living with HIV in the United States who receive their care through the Ryan White HIV/AIDS ......MORE |
People with hepatitis B who have cirrhosis should be prioritised for liver cancer screeningMichael Carter | 10 years ago Liver cancer screening for people with hepatitis B virus (HBV) infection should be targeted at thos......MORE |
PrEP will need high adherence, high effectiveness and high coverage in specific populations to be affordable in the US, New York study findsGus Cairns | 10 years ago A study based on New York City that modelled pre-exposure prophylaxis (PrEP) uptake there has found......MORE |
Approximately 4.2 million over 50s are now living with HIVMichael Carter | 10 years ago Persuasive new data showing the ageing of the global HIV epidemic has been published in the online ......MORE |
Nearly half of HIV-positive gay men could benefit from being vaccinated against HPV, say Irish researchersGus Cairns | 10 years ago A study of gay men in Ireland that has investigated the prevalence of infection with the human papi......MORE |
Treatment of worm infections leads to increases in CD4 counts and haemoglobin and fall in viral load for HIV-positive women taking ARTMichael Carter | 10 years ago De-worming is associated with falls in viral load and increases in CD4 count and haemoglobin, in pr......MORE |
London gay men: 2% of the population, a quarter of the sexually transmitted infections and half of HIV infectionsRoger Pebody | 10 years ago Men who have sex with men (MSM) living in London have particularly poor sexual health and this is w......MORE |
HIV infection associated with an increased risk of the diseases of ageingMichael Carter | 10 years ago HIV infection is associated with an increased risk of several diseases of old age, according to Dut......MORE |
HCV antibody testing may miss recent infections in gay men living with HIVMichael Carter | 10 years ago Nucleic acid testing should be used to diagnose acute hepatitis C virus (HCV) infections in gay men......MORE |
People living with HIV in the US are infrequently screened for HCVMichael Carter | 10 years ago People living with HIV are infrequently screened for hepatitis C virus (HCV) infection, according t......MORE |
Stigma, ambivalence and other priorities – explaining poor adherence to PrEP and vaginal microbicidesRoger Pebody | 10 years ago HIV stigma, the danger of being mistakenly labelled as having HIV, ambivalence about the research p......MORE |
Drug use strongly associated with sex, condomless sex and STIs in gay men living with HIV in EnglandGus Cairns | 10 years ago A large survey of gay and bisexual men living with HIV and attending eight sexual health clinics in......MORE |
Learning about additional HIV prevention methods doesn’t undermine gay men’s intentions to use condomsRoger Pebody | 10 years ago Health promotion interventions can combine information about condoms and alternative biomedical pre......MORE |
Pregnant women need more support on looking after their own health after childbirth – could help retention in Option B+ programmesRoger Pebody | 10 years ago Many women living with HIV believe that HIV care for the mother’s own health is unimportant once ......MORE |
Longer time to virological failure and less drug resistance seen in people taking Atripla than in people taking separate drugsGus Cairns | 10 years ago An analysis of people who experienced treatment failure on their first-line HIV therapy with a vira......MORE |
HIV testing rates are improving in African people in EnglandRoger Pebody | 10 years ago Data from two large, community surveys of African people living in England suggest that the proport......MORE |
Social inequalities associated with late HIV diagnosis and delayed HIV treatment – European studyRoger Pebody | 10 years ago Even in the context of western European countries with universal access to health care, there are s......MORE |
Poor knowledge of partner HIV status among South African women with recent pregnancyMichael Carter | 10 years ago Over 40% of women with recent pregnancy and a third of men with recent partner pregnancy do not kno......MORE |
Novel immune-suppressant vaccine completely blocks HIV infection in monkeys: human trials plannedGus Cairns | 10 years ago A novel and relatively simple vaccine that can be administered orally has managed to completely blo......MORE |
Late enrolment in HIV care declines in sub-Saharan Africa, but majority of people still eligible for immediate ART at diagnosisMichael Carter | 10 years ago The proportion of HIV-positive patients in sub-Saharan Africa who entered care late declined signif......MORE |
Expanded harm reduction provision achieves impressive reductions in HCV incidence among PWID in ScotlandMichael Carter | 10 years ago Implementation of comprehensive harm reduction policies has achieved impressive reductions in incid......MORE |
HIV superinfection associated with accelerated viral load increase but has no impact on clinical disease progressionMichael Carter | 10 years ago HIV superinfection has no impact on clinical disease progression, investigators report in the onlin......MORE |
Emergent HCV epidemic among young, non-urban people who inject drugs in the United StatesMichael Carter | 10 years ago Incidence of acute hepatitis C virus (HCV) infection increased significantly among young, non-urban......MORE |
CBT counselling significantly increases adherence among participants in HIV PrEP studyMichael Carter | 10 years ago A support intervention based on cognitive behavioural therapy (CBT) significantly improved adherenc......MORE |
Study in Malawi shows importance of screening HIV-positive patients for HBV co-infection and using tenofovir-containing regimensMichael Carter | 10 years ago Hepatitis B virus (HBV) genotype A1 infection is associated with poor virological control and the r......MORE |
Use of drug susceptibility testing to select therapy improves treatment outcomes in patients with MDR- and XDR-TBMichael Carter | 10 years ago New research published in the online edition of Clinical Infectious Diseases supports World Health ......MORE |
HIV prevention for black African people in the UK is under-resourced and needs to be scaled upRoger Pebody | 10 years ago NAT (National AIDS Trust) argues in a recent report that although black African communities in the ......MORE |
Study in South African township shows HIV-negative individuals often source of new TB cases in patients with HIVMichael Carter | 10 years ago HIV-negative individuals are an important source of new tuberculosis (TB) cases in HIV-positive pat......MORE |
Excellent outcomes among people starting HIV therapy at high CD4 counts in UgandaMichael Carter | 10 years ago People in Uganda starting antiretroviral therapy (ART) with higher CD4 counts can achieve excellent......MORE |
Intimate partner violence intervention reduces HIV incidence and violence against womenCarole Leach-Lemens | 10 years ago Integrating intimate partner violence (IPV) prevention strategies into HIV prevention programming l......MORE |
Risk of invasive pneumococcal disease remains high for people living with HIVMichael Carter | 10 years ago People living with HIV continue to be at increased risk of invasive pneumococcal disease, Danish in......MORE |
South African women living with HIV subtype C experience rapid CD4 cell lossMichael Carter | 10 years ago A third of women living with HIV subtype C have a fall in their CD4 count to below 350 cells/mm3 wi......MORE |
Couples-based intervention has impact on HCV incidence and risky sexual behaviour among drug-involved couples in KazakhstanMichael Carter | 10 years ago A couples-based risk reduction intervention reduced hepatitis C virus (HCV) incidence and levels of......MORE |
Self-testing has the potential to boost HIV diagnosis rates among MSM in ChinaMichael Carter | 10 years ago Self-testing has the potential to boost HIV diagnosis rates among high-risk and hard-to-reach men w......MORE |
Mothers starting antiretrovirals in Malawi lost from care more frequently, revealing weaknesses in Option B+ implementationCarole Leach-Lemens | 10 years ago Although Malawi’s policy of offering lifelong antiretroviral therapy (ART) to women living with H......MORE |
Harm reduction prevents HIV, national evidence from Ukraine and Greece showsMara Kardas-Nelson | 10 years ago Two presentations given at the 20th International AIDS Conference, held in Melbourne, Australia Jul......MORE |
Need for scaled up combination prevention for sex workers, Indian and Central American studies showMara Kardas-Nelson | 10 years ago Presentations given at a session considering HIV prevention strategies among female sex workers, wh......MORE |
Switching from first-line ART with suppressed viral load linked to treatment failureLiz Highleyman | 10 years ago People who switch away from their initial antiretroviral therapy (ART) regimen when their viral ......MORE |
Gay men interested in taking PrEP already report high-risk behaviourRoger Pebody | 10 years ago Surveys of gay men in the Netherlands and Australia suggest that some would use condoms less freque......MORE |
Young people with HIV respond well to human papillomavirus vaccineLiz Highleyman | 10 years ago The quadrivalent human papillomavirus (HPV) vaccine worked as well for teens and young adults with......MORE |
What needs to be done to make HIV self-testing a reality?Roger Pebody | 10 years ago Self-testing for HIV has great potential to broaden access to HIV testing, the 20th International A......MORE |
Nearly half of young gay men in Bangkok not using condoms consistently acquire HIV within five years of starting sexGus Cairns | 10 years ago A survey of young gay men and transgender women (MSM) in Bangkok has found that HIV incidence among......MORE |
NAM European HIV prevention survey: final resultsGus Cairns | 10 years ago A pan-European survey of opinions about HIV prevention methods, conducted by NAM last year and answ......MORE |
Of guidelines, targets and resources: the documents that defined the 2014 International AIDS ConferenceGus Cairns | 10 years ago If there was a phrase that defined the 20th International AIDS Conference, one that surfaced in eve......MORE |
Weight gain on ART may raise risk of heart disease and diabetesLiz Highleyman | 10 years ago People with HIV in the normal weight range who gain a substantial amount of weight shortly after st......MORE |
Interferon-free hepatitis C treatment works for people on methadone or buprenorphineLiz Highleyman | 10 years ago People with chronic hepatitis C who are using methadone or buprenorphine to manage opiate addiction......MORE |
Most gay men who don’t use condoms are mindful of HIV and attempt to reduce their riskRoger Pebody | 10 years ago Three-quarters of Australian gay and bisexual men who report unprotected anal intercourse with casu......MORE |
Efavirenz use not linked to neurocognitive impairmentLiz Highleyman | 10 years ago People who use antiretroviral regimens containing efavirenz (Sustiva or Stocrin, also in the Atripl......MORE |
How will people use PrEP? iPrEx users talk condoms, pills, anxiety and reliefGus Cairns | 10 years ago Interviews with participants in the US sites of the iPrEx study of pre-exposure prophylaxis show th......MORE |
The more drugs gay men have taken, the more likely they are to have unprotected sexRoger Pebody | 10 years ago The probability of gay men in England having unprotected anal intercourse is strongly associated wi......MORE |
Tackling moral judgments about sex and sexuality is vital for HIV preventionRoger Pebody | 10 years ago Scientific advances in biomedical prevention and treatment will not reach transgender people, men w......MORE |
ART demand up to 16.8 million by 2016Lesley Odendal | 10 years ago The projected demand for antiretroviral therapy (ART) will increase to 16.8 million person-years by......MORE |
Strong performance on HIV drugs for mothers doesn't guarantee optimal care for infants, survey showsCarole Leach-Lemens | 10 years ago The significant increase in access to antiretroviral therapy for all pregnant women living with HIV......MORE |
HIV is increasing in gay men in London because of lack of testing, comparative study findsGus Cairns | 10 years ago A study presented at the 20th International AIDS Conference (AIDS 2014) in Melbourne today compared......MORE |
Dolutegravir demonstrates good efficacy despite resistanceLiz Highleyman | 10 years ago Antiretroviral regimens containing the recently approved HIV integrase inhibitor dolutegravir (Tiv......MORE |
Could HIV treatment mean safer sex?Gus Cairns | 10 years ago A meta-analysis of every study that has looked at the sexual behaviour of people after starting HIV......MORE |
More data suggest increased risk of HIV infection for women using contraceptive injectionsRoger Pebody | 10 years ago A sophisticated meta-analysis, pooling individual-level data on 37,000 women, has found that the us......MORE |
Reduced treatment delays for people with drug-resistant TB and HIV co-infection through decentralised care and rapid Xpert MTB/RIF testLesley Odendal | 10 years ago Decentralisation of drug-resistant tuberculosis (DR-TB) management and use of the Xpert MTB/RIF tes......MORE |
Anal lesions often resolve without treatment in HIV-positive gay menKeith Alcorn | 10 years ago High-grade anal dysplasia is common among gay men living with HIV, but it often resolves spontaneou......MORE |
Home-testing acceptable in 'treat everyone' trial: treatment takes longer to acceptGus Cairns | 10 years ago The pilot phase of a trial in South Africa that aims to treat everyone living with HIV in a communi......MORE |
Treatment as prevention may not work in Africa without couples counsellingGus Cairns | 10 years ago A study from Zambia has found that a programme of couples voluntary counselling and testing (CVCT),......MORE |
Harm reduction funding meeting only 7% of global needKeith Alcorn | 10 years ago International donors are investing only 7% of what is needed to provide adequate harm reduction cov......MORE |
Maraviroc fails to match tenofovir/emtricitabine for first-line HIV treatmentKeith Alcorn | 10 years ago An NRTI-sparing dual antiretroviral regimen containing maraviroc (Celsentri) plus ritonavir-booste......MORE |
Meta-analysis: only half the people who start PEP complete the courseRoger Pebody | 10 years ago There are significant losses at each step of the post exposure prophylaxis (PEP) ‘treatment casca......MORE |
Globally, 1 in 12 MSM have been arrested for same-sex behaviourRoger Pebody | 10 years ago Laws which criminalise homosexual behaviour – such as those recently passed by Nigeria and Uganda......MORE |
Good adherence seen in study of intermittent PrEPGus Cairns | 10 years ago The first results published from the IPERGAY study, a trial of pre-exposure prophylaxis (PrEP) in g......MORE |
Novel techniques probed in cure researchGus Cairns | 10 years ago Two presentations at the 20th International AIDS Conference in Melbourne described new pathways bei......MORE |
Romidepsin activates latent HIV, but does not decrease viral reservoirLiz Highleyman | 10 years ago The HDAC inhibitor romidepsin was able to awaken latent HIV in resting T-cells, causing it to start......MORE |
Adolescent deaths from AIDS rising, especially among boysCarole Leach-Lemens | 10 years ago While new HIV infections have declined among children, adolescents and adults since 2000, HIV-relat......MORE |
Reappearance of HIV in "Mississippi Baby" poses questions for early treatmentGus Cairns | 10 years ago The 20th International AIDS Conference (AIDS 2014) heard yesterday that the reappearance of HIV in ......MORE |
Cash transfers plus care halve HIV risk behaviours in South African adolescentsCarole Leach-Lemens | 10 years ago Combining unconditional economic support in the form of government cash transfers, school feeding a......MORE |
AIDS 2014: Researchers discuss progress towards an HIV cureLiz Highleyman | 10 years ago Progress along the multi-pronged path towards a cure for HIV was one of the themes at the 20th In......MORE |
Overall PrEP effectiveness in iPrEx OLE study 50%, but 100% in those taking four or more doses a weekGus Cairns | 10 years ago The open-label extension of the iPrEx study of pre-exposure prophylaxis (iPrEx OLE) reported its ma......MORE |
What is needed to 'step up the pace' on HIV prevention and treatment?Keith Alcorn | 10 years ago 'Stepping up the pace', the theme of AIDS 2014, will require a new focus on key populations and ge......MORE |
Significantly less syphilis in female partners of circumcised menGus Cairns | 10 years ago A study presented today at the 20th International AIDS Conference (AIDS 2014) in Melbourne found po......MORE |
Novel TB regimen could reduce treatment durationLesley Odendal | 10 years ago A novel TB drug regimen that could treat drug-sensitive and some forms of drug-resistant TB far mor......MORE |
AbbVie 3D regimen cures most genotype 1 HCV in people with HIV and HCV co-infectionLiz Highleyman | 10 years ago An oral regimen of three direct-acting antivirals plus ribavirin taken for 12 weeks demonstrated a ......MORE |
Sofosbuvir + ribavirin cures hepatitis C for more than 80% of people with HIV and HCV co-infectionLiz Highleyman | 10 years ago An interferon-free regimen of sofosbuvir (Sovaldi) plus ribavirin for 24 weeks led to sustained hep......MORE |
Recession and income inequality have fuelled HIV infections in European drug usersRoger Pebody | 10 years ago In European countries, increases in rates of reported HIV infections among people who inject drugs ......MORE |
AIDS 2014 opening ceremony honours Flight MH17 dead with drive to end AIDS by 2030Keith Alcorn | 10 years ago The 20th International AIDS Conference (AIDS 2014) opened in Melbourne, Australia, on Sunday evenin......MORE |
European CDC cautious about PrEPGus Cairns | 10 years ago The European Centre for Disease Control (ECDC) has issued a paper saying that it cannot make a clea......MORE |
Protease inhibitor therapy doesn't reduce the risk of malaria for HIV-positive pregnant womenMichael Carter | 10 years ago Antiretroviral therapy (ART) based on the protease inhibitor lopinavir/ritonavir does not reduce th......MORE |
Study finds no evidence that HIV-positive gay men in UK have increased risk of neurocognitive impairmentMichael Carter | 10 years ago Prevalence and severity of neurocognitive impairment does not differ between HIV-positive and HIV-n......MORE |
High levels of adherence to study medication among women who conceived during HIV PrEP studyMichael Carter | 10 years ago HIV pre-exposure prophylaxis (PrEP) appears to be an acceptable strategy for safer conception for......MORE |
High rates of drug resistance among HIV-positive infants in South AfricaMichael Carter | 10 years ago There was a high prevalence of antiretroviral drug resistance among infants newly diagnosed with ......MORE |
Therapy with newer, safer antiretrovirals an option for the majority of HIV-positive patientsMichael Carter | 10 years ago The majority of patients taking antiretroviral therapy (ART) that includes drugs associated with ......MORE |
Substantial proportion of male HIV infections labelled as 'heterosexual exposure' in UK probably due to sex with other menMichael Carter | 10 years ago Up to a fifth of HIV infection among black African men initially classified as 'heterosexual exposu......MORE |
HIV prevention needs to support gay men to discuss HIV status and risk, especially in relationshipsRoger Pebody | 10 years ago Gay, bisexual and other men who have sex with men in Scotland rarely talk explicitly about HIV stat......MORE |
HIV/HCV co-infection associated with increased risk of osteoporosis and fracturesMichael Carter | 10 years ago Co-infection with HIV and hepatitis C virus (HCV) is associated with increased risks of low bone ......MORE |
Complex needs and overlapping vulnerabilities frequently reported by ‘high-risk’ gay men in ScotlandRoger Pebody | 10 years ago A quarter of Scottish gay men who are newly diagnosed with HIV or a rectal sexually transmitted inf......MORE |
Protease inhibitor therapy increases underlying genetic risk of diabetes for women with HIVMichael Carter | 10 years ago Treatment with an antiretroviral regimen based on a protease inhibitor magnifies any underlying gen......MORE |
'Robust' evidence of HIV epidemic among people who inject drugs in the Middle East and North AfricaMichael Carter | 10 years ago There is “robust” evidence of HIV epidemics among people who inject drugs (PWID) in multiple co......MORE |
High prevalence of risk behaviour means there's pontential for worsening of HIV epidemic among people who inject drugs in EuropeMichael Carter | 10 years ago Sharing of injecting equipment and sex without condoms is more frequently reported by people who in......MORE |
High prevalence of risk behaviour means there's potential for worsening of HIV epidemic among people who inject drugs in EuropeMichael Carter | 10 years ago Sharing of injecting equipment and sex without condoms is more frequently reported by people who in......MORE |
HCV is a major reason for healthcare utilisation in the United StatesMichael Carter | 10 years ago Patients with hepatitis C virus (HCV) infection are significant users of healthcare services in the......MORE |
Health interventions in online cruising environments more acceptable when they take a ‘passive’ approachRoger Pebody | 10 years ago A survey of men who have sex with men in Scotland has found that sexual health promotion is accepta......MORE |
ART soon after birth for HIV-infected babies can achieve sustained viral suppression and reduce pool of HIV-infected cellsMichael Carter | 10 years ago Antiretroviral therapy started soon after birth can suppress HIV to extremely low levels and severe......MORE |
Gay men who discuss HIV status with sexual partners are less likely to acquire HIVRoger Pebody | 10 years ago A case-control study, examining the sexual behaviour of German gay men receiving HIV-negative and H......MORE |
HIV infection due to unsafe medical injections may have fallen by almost 90% worldwide in decade after 2000Michael Carter | 10 years ago The number of HIV infections in low- and middle-income acquired due to unsafe medical injections by......MORE |
Drug-resistant gonorrhoea rates plummet in USGus Cairns | 10 years ago Preliminary results announced at the US 2014 STD Prevention Conference in Atlanta have shown that t......MORE |
Low uptake of HCV treatment in England will lead to substantial disease burden by 2035Michael Carter | 10 years ago Only 3% of patients with chronic hepatitis C virus (HCV) are treated for their infection each year ......MORE |
PrEP users say it provides an ‘extra layer of protection’ and ‘peace of mind’Roger Pebody | 10 years ago American gay men who have chosen to take pre-exposure prophylaxis (PrEP) are aware of their own ris......MORE |
Current WHO guidelines for use of ART as prevention will benefit only a "fraction" of people with higher CD4 counts and their partnersMichael Carter | 10 years ago World Health Organization (WHO) guidance on the use of antiretroviral treatment (ART) for the preve......MORE |
People starting therapy on a boosted protease inhihibitor don't need to switch after one virological failure episode, study indicatesMichael Carter | 10 years ago Remaining on the same regimen is a “reasonable” strategy for people taking first-line antiretro......MORE |
Three-quarters of women interviewed in Kenya's highest prevalence province say they prefer circumicsed partnersMichael Carter | 10 years ago Women in Kenya generally have a good understanding of the partial protection against infection with......MORE |
Three-quarters of women interviewed in Kenya's highest prevalence province say they prefer circumcised partnersMichael Carter | 10 years ago Women in Kenya generally have a good understanding of the partial protection against infection with......MORE |
Poor infection control procedures lead to HIV transmissions at haemodialysis centre in Saudi ArabiaMichael Carter | 10 years ago Breaches in infection control procedures were associated with genetically linked HIV transmissions ......MORE |
High burden of STIs among people living with HIV in Cape Town in period before they start ARTMichael Carter | 10 years ago Sexually transmitted infection (STI) rates are high among people living with HIV in the period befo......MORE |
Study shows prognostic value of viral load monitoring among people living with subtype C HIV in South AfricaMichael Carter | 10 years ago Viral load is the single most important predictor of CD4 cell loss among people in South Africa who......MORE |
Second analysis concludes that we can't eliminate the long-term possibility of HIV transmission from someone on treatmentGus Cairns | 10 years ago A study that estimates the risk that someone living with HIV and taking antiretroviral therapy coul......MORE |
Second analysis concludes that treatment doesn't eliminate the long-term risk of HIV transmissionGus Cairns | 10 years ago A mathematical model that estimates the risk of HIV transmission from someone taking antiretroviral......MORE |
Model shows potential for substantial long-term HIV risk for serodifferent couples, even with new prevention toolsGus Cairns | 10 years ago A mathematical model derived from the current knowledge about the efficacy of various different pre......MORE |
Model shows potential for substantial long-term HIV risk for serodifferent couples, even with new prevention toolsMichael Carter | 10 years ago A mathematical model derived from current knowledge about the efficacy of various different prevent......MORE |
Men living with HIV have a lower risk of prostate cancerMichael Carter | 10 years ago Incidence of prostate cancer is significantly lower among men living with HIV, investigators from C......MORE |
Tenofovir HIV PrEP causes no long-term harm to kidneysMichael Carter | 10 years ago HIV pre-exposure prophylaxis (PrEP) with tenofovir is associated with mild disturbances in kidney f......MORE |
Action needed to tackle co-infection with HIV and visceral leishmaniasis in IndiaMichael Carter | 10 years ago HIV and visceral leishmaniasis co-infection is “an under-diagnosed and under-recognised emerging ......MORE |
Low vitamin D concentrations associated with poor clinical and virological outcomes among people starting HIV therapyMichael Carter | 10 years ago Low vitamin D concentrations are associated with an increased risk of HIV disease progression among......MORE |
People living with HIV at higher risk of cancers caused by smoking or viruses, but not all cancersMichael Carter | 10 years ago The risk of cancer is increased twofold for people with HIV compared to individuals in the general ......MORE |
New US guidelines recommend PrEPGus Cairns | 10 years ago The US Centers for Disease Control and Prevention (CDC) today released new guidelines recommending ......MORE |
Daily dosing key to the efficacy of tenofovir-based HIV PrEPMichael Carter | 10 years ago Good adherence is key to the efficacy of tenofovir-based HIV pre-exposure prophylaxis (PrEP), accor......MORE |
No significant risk of resistance during treatment with Truvada PrEPMichael Carter | 10 years ago Treatment with pre-exposure prophylaxis (PrEP) does not involve a significant risk of HIV drug resi......MORE |
No significant risk of resistance if HIV infection occurs during use of Truvada PrEPMichael Carter | 10 years ago Treatment with pre-exposure prophylaxis (PrEP) does not involve a significant risk of HIV drug resi......MORE |
Even moderate drinking increases risk of advanced liver fibrosis for people with HIV and HCV co-infectionMichael Carter | 10 years ago Even moderate alcohol consumption is associated with an increased risk of advanced liver fibrosis f......MORE |
Annual HIV tests for high-risk groups and one-off screening for all others could have a big impact on UK's HIV epidemicMichael Carter | 10 years ago The UK’s HIV epidemic could be partially curtailed by annual testing of high-risk groups and one-......MORE |
Sofosbuvir + ribavirin is safe and effective for HCV recurrence after liver transplantationLiz Highleyman | 10 years ago An interferon-free combination of sofosbuvir (Sovaldi) plus ribavirin taken for up to 24 weeks led ......MORE |
Voucher incentives improve engagement with HIV care among people who inject drugsMichael Carter | 10 years ago Providing vouchers exchangeable for food or household goods boosts rates of linkage and retention i......MORE |
Sustained response to treatment reduces fatigue in hepatitis C patientsLiz Highleyman | 10 years ago Curative treatment that eliminates hepatitis C virus from the body can reduce central fatigue, one ......MORE |
Investigational protease inhibitor TMC310911 highly potent in phase 2 studyMichael Carter | 10 years ago The investigational ritonavir-boosted protease inhibitor TMC310911 has a potent antiviral effect, f......MORE |
Sofosbuvir + ribavirin for 24 weeks is highly effective against HCV genotype 4Liz Highleyman | 10 years ago A 24-week regimen of sofosbuvir (Sovaldi) plus ribavirin cured 93% of people with hard-to-treat he......MORE |
Early antiretroviral treatment reduces risk of AIDS and HIV-related illnessMichael Carter | 10 years ago Early antiretroviral therapy significantly reduced the risk of AIDS and HIV-related illness in a la......MORE |
PCR testing reveals high prevalence of CNS infections among people living with HIV in Zambia with CNS symptomsMichael Carter | 10 years ago There is a high prevalence of central nervous system (CNS) opportunistic infections among people li......MORE |
Methadone and buprenorphine-naloxone both associated with reduced HIV risk among people who inject drugsMichael Carter | 10 years ago Methadone maintenance therapy and treatment with buprenorphine-naloxone are equally effective at re......MORE |
Implementation of a comprehensive harm reduction programme curtailed the HIV epidemic among people who inject drugs in TaiwanMichael Carter | 10 years ago Implementation of a comprehensive harm reduction programme successfully contained the HIV epidemic ......MORE |
HIV infection increases risk of melanomaMichael Carter | 10 years ago HIV infection is associated with an increased risk of melanoma, according to the results of a meta-......MORE |
Three-drug AbbVie combination safe and highly effective in treatment of post-transplant hepatitis C recurrenceKeith Alcorn | 10 years ago A three-drug combination of direct-acting antivirals developed by AbbVie cured hepatitis C genotype......MORE |
Sofosbuvir for hepatitis C works well despite multiple negative predictive factorsLiz Highleyman | 10 years ago Hepatitis C treatment using sofosbuvir (Sovaldi) is highly effective even for people with multiple ......MORE |
People living with HIV in the UK still have impaired health-related quality of lifeMichael Carter | 10 years ago People living with HIV in the UK have poorer health-related quality of life (HRQoL) compared to ind......MORE |
Sofosbuvir + new GS-5816 NS5A inhibitor is effective against hepatitis C genotypes 1-6Liz Highleyman | 10 years ago A new experimental NS5A inhibitor, GS-5816, was shown to be safe and effective when used in an inte......MORE |
'Chem sex' commonly reported by UK gay men diagnosed with shigellaMichael Carter | 10 years ago 'Chem sex' (taking recreational drugs during sex) and attendance at sex parties are commonly repo......MORE |
BMS combination cures 90% of genotype 1b hepatitis C in 24 weeksKeith Alcorn | 10 years ago A combination of two direct-acting antivirals developed by Bristol-Myers Squibb (BMS) cured 90% of ......MORE |
Sofosbuvir + ribavirin is safe and effective for people with hepatitis C who have advanced liver diseaseLiz Highleyman | 10 years ago Sofosbuvir plus ribavirin is a safe option that can lead to sustained response in people with advan......MORE |
Abolishing HIV in RwandaGus Cairns | 10 years ago The achievement of universal HIV coverage in one African country, Rwanda, has resulted in HIV diagn......MORE |
Adding interferon to nucleoside antivirals may improve response for people with chronic hepatitis BLiz Highleyman | 10 years ago Adding pegylated interferon to entecavir (Baraclude) led to greater hepatitis B virus (HBV) viral l......MORE |
AbbVie 3-drug combination cures 92 to 96% of hepatitis C patients with cirrhosisKeith Alcorn | 10 years ago The largest study of new direct-acting antivirals yet conducted in people with hepatitis C genotype......MORE |
AbbVie 2-drug combination + ribavirin achieves 100% cure in previously untreated genotype 4 hepatitis CKeith Alcorn | 10 years ago A combination of two direct-acting antivirals developed by AbbVie cured 100% of previously untreate......MORE |
Sofosbuvir/ledipasvir coformulation cures more than 90% of treatment-naive and retreated genotype 1 patientsLiz Highleyman | 10 years ago A coformulation of sofosbuvir and ledipasvir taken for as little as 8 weeks produced high sustaine......MORE |
Sofosbuvir/ledipasvir co-formulation cures more than 90% of treatment-naive and retreated genotype 1 patientsLiz Highleyman | 10 years ago A co-formulation of sofosbuvir and ledipasvir taken for as little as eight weeks produced high sus......MORE |
Sofosbuvir + simeprevir dual therapy shows high cure rates for hepatitis C patients with or without cirrhosisLiz Highleyman | 10 years ago A 12-week oral regimen of sofosbuvir (Sovaldi) plus simeprevir (Olysio) without pegylated interfero......MORE |
European liver specialists recommend `mix-and-match` approach to new hepatitis C drugsKeith Alcorn | 10 years ago The European Association for the Study of the Liver has issued new guidelines for the treatment of ......MORE |
European liver specialists recommend 'mix-and-match' approach to new hepatitis C drugsKeith Alcorn | 10 years ago The European Association for the Study of the Liver (EASL) has issued new guidelines for the treatm......MORE |
Sofosbuvir/ledipasvir produces early cure for 100% of people with HIV and HCV co-infectionLiz Highleyman | 10 years ago Treatment for 12 weeks with a co-formulation of sofosbuvir and ledipasvir led to sustained respons......MORE |
Sofosbuvir/ledipasvir produces early cure for 100% of HIV/HCV coinfected patientsLiz Highleyman | 10 years ago Treatment for 12 weeks with a coformulation of sofosbuvir and ledipasvir led to sustained response......MORE |
Sofosbuvir/ledipasvir is safe and effective for relapsers and hard-to-treat patientsLiz Highleyman | 10 years ago A coformulation of sofosbuvir and ledipasvir successfully treated a variety of difficult-to-treat p......MORE |
88% of previous relapsers achieve hepatitis C cure with simeprevir-based triple therapyKeith Alcorn | 10 years ago Almost 90% of European patients who had relapsed after previous treatment with pegylated interferon......MORE |
AbbVie interferon-free regimen cures 96% of treatment-experienced genotype 1 hepatitis C infectionsKeith Alcorn | 10 years ago A 12-week course of three direct-acting antivirals developed by AbbVie, plus ribavirin, cured 96.3%......MORE |
Can we provide point-of-care viral load tests in poor countries?Gus Cairns | 10 years ago It is not impossible to provide mobile, point-of-care viral load tests in resource-poor settings, t......MORE |
PROUD UK PrEP study completes enrolment - first data gives participants' background and risk factorsGus Cairns | 10 years ago The pilot stage of the PROUD study - the UK's study of HIV pre-exposure prophylaxis (taking HIV dru......MORE |
PROUD UK PrEP study completes enrolment – first data give participants' background and risk factorsGus Cairns | 10 years ago The pilot stage of the PROUD study – the UK's study of HIV pre-exposure prophylaxis (HIV-negative......MORE |
WHO recommends global use of newest hepatitis C drugs, urges price reductionsKeith Alcorn | 10 years ago The World Health Organization has issued global treatment guidelines for hepatitis C, strongly reco......MORE |
Low CD4 count during HIV therapy increases risk of virus-related non-AIDS cancersMichael Carter | 10 years ago A poor CD4 response to antiretroviral therapy (ART) is associated with an increased risk of virus-r......MORE |
Giving treatment to specific high-risk people may bring down HIV faster than distributing it equallyGus Cairns | 10 years ago In a concentrated epidemic, HIV is mainly restricted to – or at least more common in – specific......MORE |
Expanded HIV testing may find more acute infections as well as more late presentersGus Cairns | 10 years ago Expanding HIV testing into local hospitals and primary care may not only find more people who have ......MORE |
Home sampling for HIV testing – high demand, 1 in 60 are HIV positiveRoger Pebody | 10 years ago Pilot projects, testing innovative ways for individuals to take their own saliva or blood sample an......MORE |
Home sampling for HIV testing – high demand, 1 in 60 are HIV positiveRoger Pebody | 10 years ago Pilot projects, testing innovative ways for individuals to take their own saliva or blood sample an......MORE |
An estimated 29,000 undiagnosed HIV cases in FranceMichael Carter | 10 years ago An estimated 29,000 individuals in France were living with undiagnosed HIV infection in 2010, inves......MORE |
No simple relationship between drug use and risky sex in London gay menRoger Pebody | 10 years ago Gay men involved in ‘chemsex’ (taking recreational drugs such as mephedrone, GHB/GBL and crysta......MORE |
Standard HIV treatment achieves high concentrations in female genital tract and suppresses shedding of virusMichael Carter | 10 years ago Standard antiretroviral therapy containing tenofovir, FTC and atazanavir achieves high concentratio......MORE |
HIV viral load in semen can differ in two samples provided within one hourMichael Carter | 10 years ago HIV can be intermittently detectable in the semen of men taking long-term antiretroviral therapy th......MORE |
Risk score can help predict which people living with HIV have highest risk of kidney disease during tenofovir treatmentMichael Carter | 10 years ago Investigators in the United States have developed a risk score to predict which people living with ......MORE |
Hepatitis delta virus co-infection increases risk of poor liver-related outcomes for people living with HIVMichael Carter | 10 years ago Co-infection with hepatitis delta virus (HDV) is a major risk factor for hepatic decompensation and......MORE |
South African treatment guidelines need to consider viral load, not CD4 count, to achieve greater impact of treatment as prevention: studyMichael Carter | 10 years ago Recommendations about the initiation of antiretroviral therapy (ART) need to change for the use of ......MORE |
Interferon-free BMS combo cures 90% of genotype 1 hepatitis CLiz Highleyman | 10 years ago An all-oral regimen of daclatasvir, asunaprevir and BMS-791325 – without interferon or ribavirin ......MORE |
HIV incidence is high among pregnant and postpartum women and increases the risk of mother-to-child transmissionMichael Carter | 10 years ago HIV incidence is high among pregnant and postpartum women and is associated with an increased risk ......MORE |
Merck combination suppresses HCV in mono-infected and co-infected patientsLiz Highleyman | 10 years ago An all-oral combination of the hepatitis C virus (HCV) protease inhibitor MK-5172 and NS5A inhibito......MORE |
Early treatment reduces viral reservoirs but does not prevent reboundLiz Highleyman | 10 years ago Antiretroviral therapy started during the first several days after infection limited dissemination ......MORE |
Dapivirine vaginal ring safe and effective in tissue study, but maraviroc component doesn't workLiz Highleyman | 10 years ago Vaginal rings containing the experimental NNRTI dapivirine were well tolerated and blocked HIV infe......MORE |
Early antiretroviral therapy may limit gut damage and immune activationLiz Highleyman | 10 years ago Starting antiretroviral therapy (ART) at the earliest stage of HIV infection can help prevent immun......MORE |
Women with circumcised partners less likely to have HIV, no less likely to use condomsGus Cairns | 10 years ago A study from Orange Farm near Johannesburg in South Africa, the area that hosted the first-ever ran......MORE |
High rate of new infections with HPV types associated with a high risk of anal cancer among gay men living with HIVMichael Carter | 10 years ago Incidence of anal infection with cancer-associated strains of human papillomavirus (HPV) is high am......MORE |
Monitoring may be an option for people living with HIV diagnosed with high-grade pre-cancerous anal lesionsMichael Carter | 10 years ago Up to 62% of people living with HIV who have high-grade pre-cancerous cell changes may experience a......MORE |
Rare case of lesbian transmission of HIV reported in USMichael Carter | 10 years ago An extremely rare case of female-to-female sexual transmission of HIV has been reported in the Unit......MORE |
Very different levels of PrEP uptake and adherence in three US cities, demonstration project findsGus Cairns | 10 years ago One of the first studies of open-label pre-exposure prophylaxis (PrEP) for at-risk gay men in three......MORE |
Heart attack link to abacavir persists in D:A:D studyGus Cairns | 10 years ago The nucleoside (NRTI) drug abacavir (Ziagen also in Kivexa/Epzicom) continues to be associated with......MORE |
Daclatasvir plus simeprevir are effective against hepatitis C genotype 1bLiz Highleyman | 10 years ago An all-oral regimen of daclatasvir plus simeprevir, without interferon or ribavirin, led to sustain......MORE |
Efavirenz-based ART matches lopinavir/ritonavir for perinatal HIV treatmentCarole Leach-Lemens | 10 years ago Pregnant women taking efavirenz-based antiretroviral therapy had significantly better virologic out......MORE |
Massive scale-up of HIV testing, plus HIV treatment on diagnosis, needed to curtail UK gay epidemicRoger Pebody | 10 years ago Increasing the proportion of HIV-positive gay men in the UK who have an undetectable viral load fro......MORE |
Only having sex with same-status partners is an HIV prevention strategy for 40% of gay menGus Cairns | 10 years ago A study from Seattle has found that only having sex with men of the same HIV status was by far the ......MORE |
Rejecting serodiscordant partners is HIV prevention strategy of choice for 40% of gay menGus Cairns | 10 years ago A study from Seattle has found that avoiding men of the opposite HIV status was by far the most com......MORE |
Sexually transmitted infections greatly increase the risk of HIV infection in pregnancyCarole Leach-Lemens | 10 years ago Pregnant women in Kenya have a similar risk of HIV infection during pregnancy to serodiscordant cou......MORE |
New NNRTI doravirine matches efavirenz for first-line HIV treatmentLiz Highleyman | 10 years ago The next-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) doravirine (formerly MK-......MORE |
Lopinavir/ritonavir or 3TC PrEP equally protective against infant HIV infection during breastfeedingCarole Leach-Lemens | 10 years ago Lopinavir/ritonavir (Kaletra) or 3TC (lamivudine, Epivir) proved equally protective as infant proph......MORE |
Heart attack risk in people with HIV may be falling – but not in womenGus Cairns | 10 years ago A number of studies at last week’s Conference on Retroviruses and Opportunistic Infections (CROI)......MORE |
Nipping HIV in the bud: could we use genotyping to interrupt transmission?Gus Cairns | 10 years ago The Conference on Retroviruses and Opportunistic Infections (CROI) this year heard a number of pres......MORE |
Novel two-drug maintenance combination works at least as well as triple therapy: stage set for long-lasting injectable formulationGus Cairns | 10 years ago An oral combination therapy of two antiretroviral drugs, the non-nucleoside rilpivirine (Edurant, a......MORE |
Protected T-cells persist and proliferate in HIV gene therapy studyLiz Highleyman | 10 years ago Genetically modified CD4 T-cells lacking CCR5 co-receptors reach high levels in the body and are re......MORE |
Raltegravir has the edge over two protease inhibitors in three-drug comparison studyGus Cairns | 10 years ago In a head-to-head comparison of three drugs presented at the 21st Conference on Retroviruses and Op......MORE |
The 'Boston patients' experience HIV rebound after stem cell transplantsLiz Highleyman | 10 years ago HIV has re-emerged in two Boston men who underwent experimental antiretroviral therapy interruption......MORE |
Younger women not at higher risk of HIV from relationships with older men, South African study findsKeith Alcorn | 10 years ago Sex with older men is not placing women under 30 at higher risk of HIV infection in rural South Afr......MORE |
Self-testing encourages very high uptake of HIV testing in Malawi studyKeith Alcorn | 10 years ago A community-based self-testing programme achieved 76% uptake of HIV testing in urban Malawi, with v......MORE |
Male life expectancy nine years shorter due to lower male uptake of HIV treatment in rural South AfricaKeith Alcorn | 10 years ago Male life expectancy in rural South Africa has improved far less dramatically than women’s life e......MORE |
Raltegravir plus boosted darunavir shown to be safe and effective for first-line ARTLiz Highleyman | 10 years ago An NRTI-sparing initial regimen of raltegravir (Isentress) plus boosted darunavir (Prezista) worked......MORE |
HIV attachment inhibitor BMS-663068 shows good safety and efficacy in phase 2b studyLiz Highleyman | 10 years ago Combination therapy using a novel HIV attachment inhibitor demonstrated good safety and effectivene......MORE |
Maternal deaths due to HIV not declining despite PMTCT successes in South AfricaKeith Alcorn | 10 years ago Improvements in prevention of mother-to-child transmission of HIV (PMTCT) in South Africa are not t......MORE |
HIV incidence at record high in young gay black men in southern USAGus Cairns | 10 years ago HIV incidence in young black gay men in Atlanta, Georgia in the US is running at 12.1% a year – o......MORE |
People with HIV more likely to die after diagnosis of many common cancers in USKeith Alcorn | 10 years ago People with HIV are more likely to die from many common cancers than the rest of the US population,......MORE |
Monkey studies confirm viability of injectable PrEP drugGus Cairns | 10 years ago Two studies in monkeys of an injectable formulation of the third-generation integrase inhibitor dr......MORE |
Sofosbuvir & ribavirin cures 75% of genotype 1 HIV/HCV co-infected patientsLiz Highleyman | 10 years ago An interferon-free regimen of sofosbuvir plus ribavirin for 24 weeks led to sustained response in t......MORE |
AbbVie '3D' combination cures 99% of genotype 1b hepatitis CKeith Alcorn | 10 years ago A 12-week triple combination of direct-acting antivirals developed by AbbVie cured at least 99% of ......MORE |
Simeprevir cures almost 80% of first-time coinfected hepatitis C patientsKeith Alcorn | 10 years ago The next-generation hepatitis C protease inhibitor simeprevir cured almost 80% of previously untre......MORE |
Simeprevir cures almost 80% of first-time co-infected hepatitis C patientsKeith Alcorn | 10 years ago The next-generation hepatitis C protease inhibitor simeprevir cured almost 80% of previously untre......MORE |
Faldaprevir plus interferon and ribavirin cures hepatitis C in most people with HIV/HCV co-infectionLiz Highleyman | 10 years ago The hepatitis C protease inhibitor faldaprevir added to pegylated interferon and ribavirin cured he......MORE |
Six-week oral treatment can cure hard-to-treat hepatitis C patientsLiz Highleyman | 10 years ago Interferon- and ribavirin-free treatment using sofosbuvir, ledipasvir and a third direct-acting dru......MORE |
No-one with an undetectable viral load, gay or heterosexual, transmits HIV in first two years of PARTNER studyGus Cairns | 10 years ago The second large study to look at whether people with HIV become non-infectious if they are on anti......MORE |
A cure may need multiple components, workshop delegates hearGus Cairns | 10 years ago Delegates at the community cure workshop in advance of the 21st Conference on Retroviruses and Oppo......MORE |
Older age associated with bigger increases in viral load and falls in CD4 count in patients not taking HIV treatmentMichael Carter | 10 years ago Results of a large observational study underline the importance of closely monitoring viral load in......MORE |
Reconnecting patients lost to follow-up with care can prevent new HIV transmissionsMichael Carter | 10 years ago The number of HIV transmissions can be reduced by tracing patients who drop out of HIV care, accord......MORE |
Big gaps in engagement with HIV care and virological suppression between US statesMichael Carter | 10 years ago The proportion of people living with HIV linked to and retained in HIV care varies considerably bet......MORE |
Guidelines for HIV testing in non-specialist settings not being followed in the UKMichael Carter | 10 years ago UK guidelines issued in 2008 concerning HIV testing in general medical and primary care settings ar......MORE |
HIV treatment as prevention: the Ugandan experienceMichael Carter | 10 years ago Antiretroviral therapy (ART) is associated with a substantial and sustained reduction in the risk o......MORE |
Young people who acquire HIV in Uganda report poor communication and mistrust in their relationshipsRoger Pebody | 10 years ago Compared with young people who remain HIV negative, recent seroconverters in Rakai, Uganda describe......MORE |
HIV treatment as prevention: the experience in British ColumbiaMichael Carter | 10 years ago Expanded coverage of HIV therapy in British Columbia has been accompanied by a 42% reduction in HIV......MORE |
Truvada PrEP does not harm the kidneys, trial showsMichael Carter | 10 years ago HIV pre-exposure prophylaxis (PrEP) with FTC/tenofovir (Truvada) is associated with only mild distu......MORE |
HIV prevalence and incidence fall in KenyaMichael Carter | 10 years ago HIV incidence and prevalence are declining in Kenya, investigators report in the online edition of ......MORE |
A low CD4 cell count despite viral suppression with HIV treatment is associated with a big increase in mortality riskMichael Carter | 10 years ago A low CD4 cell count is associated with increased mortality risk, even if people are taking virolog......MORE |
Wide range of factors contribute to high HIV risk among black MSM in the USMichael Carter | 10 years ago Demographic, behavioural, economic and biological factors are all associated with increased HIV ris......MORE |
Dosing errors of liquid AZT "exceedingly" common and related to poorer HIV health literacyMichael Carter | 10 years ago Dosing errors are “exceedingly” common when adults are preparing paediatric doses of liquid ant......MORE |
Unprotected receptive anal sex is the key risk factor among UK gay men for rectal LGV infectionMichael Carter | 10 years ago Unprotected receptive anal sex is the key risk factor for rectal LGV (lymphogranuloma venereum) inf......MORE |
Black people have low levels of engagement and retention in HIV care in the USMichael Carter | 10 years ago Intensified efforts are needed to improve engagement by black people in the HIV care continuum in t......MORE |
High incidence of antiretroviral prescribing errors in NigeriaMichael Carter | 10 years ago Antiretroviral prescribing errors are common in Nigeria, according to results of a large prospectiv......MORE |
‘Not quite normal’ – exploring poor mental health in gay menRoger Pebody | 10 years ago Although legal and social equality for gay people is further advanced in the Netherlands than in mo......MORE |
HIV associated with increased risk of MDR-TBMichael Carter | 10 years ago HIV infection is associated with an increased risk of multi-drug-resistant tuberculosis (MDR-TB), r......MORE |
HIV increases fracture risk, say DanesMichael Carter | 10 years ago HIV infection increases the risk of fractures, Danish investigators report in the online edition of......MORE |
Close link between HIV and hepatitis C transmission networksMichael Carter | 10 years ago HIV and hepatitis C virus (HCV) transmission networks are closely linked, according to Swiss resear......MORE |
HIV testing interventions should challenge fears of a positive resultRoger Pebody | 10 years ago Among gay and bisexual men in Glasgow, not having recently taken an HIV test is associated with bei......MORE |
Higher pill burden is associated with poorer adherence to HIV therapy and reduced chances of achieving an undetectable viral loadMichael Carter | 10 years ago Lower pill burden is associated with higher rates of adherence to HIV treatment and better virologi......MORE |
Gay and bisexual men in UK warned of Shigella outbreakMichael Carter | 10 years ago Gay and bisexual men in the UK are being targeted with a new health information campaign warning th......MORE |
US medical societies launch new hepatitis C treatment guidelinesLiz Highleyman | 10 years ago The American Association for the Study of Liver Diseases (AASLD), Infectious Diseases Society of Am......MORE |
Average CD4 cell count at time HIV therapy was started increased among young people in New York City after 2009Michael Carter | 10 years ago The average CD4 cell count at which young people living with HIV in New York City started antiretro......MORE |
Taking one to tango: how restricting responsibility for safer sex to individuals hinders talking about safer sexGus Cairns | 10 years ago A discussion paper based on a Canadian project that invited HIV-negative and HIV-positive gay men t......MORE |
Successful HIV drug resistance testing is possible when viral load is lowMichael Carter | 10 years ago HIV drug resistance testing can perform well, even when viral load is as low as 250 copies/ml, resu......MORE |
Ongoing challenges in providing PMTCT in Kenya and MalawiLesley Odendal | 10 years ago Ongoing systemic issues are affecting the implementation of the 2010 World Health Organisation (WHO......MORE |
Significant attrition at each step of the HIV care 'cascade' in British ColumbiaMichael Carter | 10 years ago Patients are being lost at each stage of the HIV care ‘cascade’ in British Columbia, Canada. In......MORE |
Long-term immune response to vaccines is impaired in people with HIVMichael Carter | 10 years ago The long-term immune response to most vaccines is impaired in people with HIV, according to the res......MORE |
Cotrimoxazole prophylaxis neither reduces TB risk nor complicates TB diagnosis in people with HIVMichael Carter | 10 years ago Cotrimoxazole prophylaxis has no impact on incidence or detection of tuberculosis (TB) in people wi......MORE |
Modelling study – self testing could lead to more HIV infectionsRoger Pebody | 10 years ago If gay men replace clinic-based HIV testing with less sensitive home tests, the prevalence and inci......MORE |
Testing HCV positive has a sustained impact on drug injecting behaviourMichael Carter | 10 years ago Diagnosis with hepatitis C virus (HCV) is associated with a sustained reduction in injecting drug u......MORE |
Gay men’s HIV risk varies hugely between individuals and over time, cohort study findsGus Cairns | 10 years ago A study that looked at the way risk of HIV transmission changed over time in a group of gay men dur......MORE |
Low lymphocyte count a risk factor for infections for people taking HCV therapyMichael Carter | 10 years ago A low lymphocyte count is associated with an increased risk of infections during hepatitis C virus ......MORE |
Opt-out HIV testing for acute medical admissions to UK hospitals worksMichael Carter | 10 years ago Opt-out HIV testing for general medical admissions to hospital is feasible, cost-effective and lead......MORE |
Immune suppression associated with reduced risk of TB transmission to household contacts of people with HIV/TB co-infectionMichael Carter | 10 years ago HIV-related immune suppression is associated with a reduced risk of tuberculosis (TB) transmission ......MORE |
Computerised counselling for patients taking HIV therapy can reduce viral load, improve treatment adherence and reduce rates of risky sexMichael Carter | 10 years ago Computerised counselling can achieve reductions in viral load and HIV transmission risk behaviour, ......MORE |
Study identifies factors associated with mortality in HIV-positive people with cryptococcal meningitisMichael Carter | 10 years ago Rapid diagnosis and effective antifungal therapy are essential to reduce mortality rates in HIV-pos......MORE |
Regular clinic attendance especially beneficial for people with HIV who have low CD4 countsMichael Carter | 10 years ago People taking HIV treatment who have a low CD4 cell count are especially likely to achieve an undet......MORE |
High viral load levels in young people newly linked with HIV care in the USMichael Carter | 10 years ago Approximately a third of young people newly linked to HIV care in the United States have viral load......MORE |
African studies identify strategies for improving treatment adherence, retention in careMara Kardas-Nelson | 10 years ago Getting people tested for HIV is one thing; getting them onto antiretrovirals (ARVs) another; and r......MORE |
TB/HIV programmatic challenges highlighted at ICASALesley Odendal | 10 years ago The presence of tuberculosis (TB) at the initiation of antiretroviral therapy (ART) predicts retent......MORE |
Life expectancy now considerably exceeds the average in some people with HIV in the USGus Cairns | 10 years ago A study from the US has found that some groups of people with HIV, especially those treated before ......MORE |
Large US study shows which HIV tests are most accurateRoger Pebody | 10 years ago Differences in the performance of commonly used HIV tests lead to substantial differences in the nu......MORE |
People newly diagnosed with HIV/STIs often have individuals with undiagnosed HIV in their social networkMichael Carter | 10 years ago Asking people who are newly diagnosed with HIV or a sexually transmitted infection (STI) to recruit......MORE |
Patients newly diagnosed with HIV/STIs often have individuals with undiagnosed HIV in their social networkMichael Carter | 10 years ago Asking patients newly diagnosed with HIV or a sexually transmitted infection (STI) to recruit conta......MORE |
Short course of ART during primary HIV therapy has immunological and virological benefits after treatment is stoppedMichael Carter | 10 years ago A short course of antiretroviral therapy during primary HIV infection (PHI) has immunological and v......MORE |
Short course of ART during primary HIV infection has immunological and virological benefits after treatment is stoppedMichael Carter | 10 years ago A short course of antiretroviral therapy during primary HIV infection (PHI) has immunological and v......MORE |
Botswana's ART programme achieves good resultsMichael Carter | 10 years ago Botswana’s antiretroviral treatment (ART) programme has achieved good results, analysis of nine y......MORE |
Implementing viral load testing in resource-limited settings: one size does not fit allMara Kardas-Nelson | 10 years ago Routine viral load can be done in low-resource settings, Helen Bygrave of Médecins Sans Frontière......MORE |
Decentralisation of care reduces HIV and TB-related deaths, illness in Swaziland and UgandaMara Kardas-Nelson | 10 years ago New studies from Eastern and Southern Africa add to mounting evidence that anti-retroviral therap......MORE |
Gilead two-drug hep C combination cures 94% of genotype 1 patients in eight weeksKeith Alcorn | 10 years ago A two-drug combination of sofosbuvir and ledipasvir cured 94% of previously untreated patients with......MORE |
Gilead two-drug hep C combination cures 94% of genotype 1 patients in 8 weeksKeith Alcorn | 10 years ago A two-drug combination of sofosbuvir and ledipasvir cured 94% of previously untreated patients with......MORE |
Health systems, not family factors, most crucial in PMTCT outcomes, Kenyan study showsLesley Odendal | 10 years ago Women who learn of their HIV infection during pregnancy are at higher risk of vertical transmission......MORE |
Widespread support for HIV PrEP among infectious disease doctors in the US and CanadaMichael Carter | 10 years ago Three-quarters of infectious disease specialists in the United States and Canada are supportive of ......MORE |
Starting antiretroviral therapy significantly reduces the risk of decompensated liver disease for men with HIV/HCV co-infectionMichael Carter | 10 years ago Starting antiretroviral therapy (ART) significantly reduces the risk of serious liver disease for p......MORE |
Study provides information on sexual health of male sex workers in EnglandMichael Carter | 10 years ago Male sex workers are significantly more likely to be diagnosed with certain sexually transmitted in......MORE |
HIV treatment in South Africa has had "astounding" benefitsMichael Carter | 10 years ago The roll-out of antiretroviral therapy (ART) in South Africa has achieved “astounding” results,......MORE |
Good adherence to HIV treatment, undetectable viral load, reduce the risk of anal infection with high-risk HPV types for MSM with HIVMichael Carter | 10 years ago Prevalence of anal HPV (human papillomavirus) infection is significantly higher among men with HIV ......MORE |
Men with penile HPV infection have an increased risk of acquiring HIVMichael Carter | 10 years ago Men with penile human papillomavirus (HPV) infection have an increased risk of acquiring HIV, inves......MORE |
NAM prevention survey results: testing underestimated, support for treatment as prevention, reservations about PrEPGus Cairns | 10 years ago A survey of beliefs and opinions on HIV prevention options, conducted by NAM as part of a programme......MORE |
NAM prevention survey: support for treatment as prevention, but reservations about PrEPGus Cairns | 10 years ago A survey of beliefs and opinions on HIV prevention options, conducted by NAM as part of a programme......MORE |
Severity of HIV seroconversion illness associated with subsequent disease progressionMichael Carter | 10 years ago Severity of symptoms during primary HIV infection (PHI) is associated with subsequent disease progr......MORE |
For women, HIV treatment based on atazanavir/ritonavir involves twice the risk of failure compared to efavirenz-containing therapyMichael Carter | 10 years ago Treatment outcomes differ between women taking first-line antiretroviral therapy based on ritonavir......MORE |
Hepatitis C virus dried on inanimate surfaces can remain infectious for up to six weeksMichael Carter | 10 years ago Dried spots of blood contaminated with hepatitis C virus (HCV) can remain infectious for up to six ......MORE |
Major UK study shows rise in HIV testing, but only a quarter of gay men tested in previous yearRoger Pebody | 10 years ago Data from three, large representative samples of the UK population over the last two decades show a......MORE |
Increasing diversity of sexual experience – major UK studyRoger Pebody | 10 years ago There has been significant change in British people’s sexual behaviour and attitudes in recent de......MORE |
Condomless sex increasing in US gay men – especially in HIV-negative and untested menGus Cairns | 10 years ago The proportion of gay men in the US who have had anal sex without a condom at least once in the pas......MORE |
Entecavir + tenofovir works well for people with hepatitis B who have had prior treatment failureLiz Highleyman | 10 years ago A dual regimen of entecavir (Baraclude) plus tenofovir (Viread) for 48 weeks led to virological res......MORE |
Micronutrient supplements delay HIV disease progression for patients with higher CD4 cell countsMichael Carter | 10 years ago Long-term micronutrient supplementation delays HIV disease progression in patients with higher CD4 ......MORE |
Early ART only increases TB IRIS risk for people with HIV who have a CD4 cell count below 50Michael Carter | 10 years ago A low CD4 cell count increases the risk of immune reconstitution inflammatory syndrome (IRIS) for p......MORE |
Faldaprevir effective across patient sub-groups with several baseline characteristics associated with treatment outcomesMichael Carter | 10 years ago The experimental hepatitis C virus (HCV) protease inhibitor is efficacious across a range of subgro......MORE |
After diagnosis of hepatitis C, some gay men willing to consider risk-reduction practicesRoger Pebody | 10 years ago HIV-positive gay men living with HIV in France need better information about the sexual transmissio......MORE |
Proportion of people in southern Africa starting ART with advanced HIV disease fallsMichael Carter | 10 years ago The proportion of people in sub-Saharan Africa who started antiretroviral therapy (ART) with advanc......MORE |
Ritonavir the cause of the interaction between telaprevir and ritonavir-boosted atazanavirMichael Carter | 10 years ago Ritonavir is the cause of the detrimental bi-directional interaction between telaprevir and ritonav......MORE |
Urgent need to address "resurgent" gay global epidemic, says English public health chiefGus Cairns | 10 years ago There is an increasing and potentially catastrophic HIV and sexual health epidemic in gay men and m......MORE |
Partner notification highly effective at finding new HIV cases, but a third who could be tested are missedGus Cairns | 10 years ago Systematically contacting and notifying the sexual partners of people newly diagnosed with HIV is a......MORE |
Faldaprevir safe and effective in HCV treatment-experienced patientsMichael Carter | 10 years ago The investigational hepatitis C virus (HCV) protease inhibitor faldaprevir is a safe and effective ......MORE |
People who aren't taking HIV treatment are a major source of transmitted resistance in Swiss gay menMichael Carter | 10 years ago Individuals who have never taken antiretroviral therapy (ART) are the main source of transmitted HI......MORE |
Largest ever number of HIV diagnoses in UK gay men – due to increased testing and new infectionsRoger Pebody | 10 years ago 3250 gay men were diagnosed with HIV in the United Kingdom during 2012, the largest number of cases......MORE |
Systematic review and meta-analysis shows equivalence of 3TC and FTCMichael Carter | 10 years ago The nucleoside reverse transcriptase inhibitors (NRTIs) 3TC and FTC are equally effective, results ......MORE |
AbbVie reports 96% cure rate for interferon-free hepatitis C regimen in phase 3 studyKeith Alcorn | 10 years ago An interferon-free combination of three drugs plus ribavirin achieved a sustained virologic respons......MORE |
Church attendance associated with late HIV diagnosis among US MSMMichael Carter | 10 years ago Church attendance is associated with late HIV diagnosis among men who have sex with men (MSM), acco......MORE |
Successful hepatitis C treatment reduces risk of liver cancer and death, but most remain untreatedLiz Highleyman | 10 years ago Hepatitis C treatment that leads to viral suppression significantly reduces the likelihood of liver......MORE |
Harm reduction works: extremely low HIV incidence over almost 20 years among people who inject drugs in AustraliaMichael Carter | 10 years ago Incidence of new HIV infections among people who inject drugs in Australia is extremely low, result......MORE |
Sofosbuvir/ribavirin for 24 weeks cures most genotype 3 hepatitis C patients, adding interferon may help difficult-to-treatLiz Highleyman | 10 years ago A dual oral regimen of sofosbuvir plus ribavirin led to sustained response for 93% of genotype 2 he......MORE |
Faldaprevir plus pegylated interferon/ribavirin leads to early sustained response in people with HIV and HCV co-infectionLiz Highleyman | 10 years ago The hepatitis C protease inhibitor faldaprevir plus pegylated interferon and ribavirin improved 4-w......MORE |
Rifampicin dose can be increased safely in TB treatment, may shorten durationMara Kardas-Nelson | 10 years ago Increasing the daily dose of rifampicin within the current TB treatment regimen from 10mg/kg to 15m......MORE |
Audit shows many high HIV prevalence areas in England are failing to expand HIV testingMichael Carter | 10 years ago Most sexual health commissioners for areas in England with a high HIV prevalence have introduced so......MORE |
Daclatasvir + asunaprevir cures 85% of genotype 1b hepatitis C patients in Japanese studyLiz Highleyman | 10 years ago An interferon- and ribavirin-free oral regimen of daclatasvir plus asunaprevir taken for 24 weeks l......MORE |
Fixed-dose sofosbuvir/ledipasvir with or without ribavirin cures most genotype 1 hepatitis C patients, LONESTAR study showsLiz Highleyman | 10 years ago At least 95% of newly treated people with genotype 1 hepatitis C and prior non-responders achieved ......MORE |
Another negative result in the quest for a shorter TB treatment courseMara Kardas-Nelson | 10 years ago Results from a Phase III trial that attempted to shorten the treatment duration for drug-sensitive ......MORE |
Sofosbuvir taken before or after liver transplant reduces hepatitis C recurrenceLiz Highleyman | 11 years ago An interferon-free combination of sofosbuvir plus ribavirin administered before liver transplantati......MORE |
HIV may be becoming less fit as it adapts to the immune systemGus Cairns | 11 years ago HIV, at least in some parts of the world, may be developing a lower replicative capacity as it adap......MORE |
Hepatitis B treatment with entecavir or tenofovir lowers, but does not eliminate, liver cancer riskLiz Highleyman | 11 years ago Long-term treatment with entecavir can reduce the likelihood that people with chronic hepatitis B w......MORE |
Sofosbuvir + ribavirin produces sustained response in 76% of genotype 1 HIV/HCV co-infected peopleLiz Highleyman | 11 years ago An interferon-free regimen of sofosbuvir plus ribavirin taken for 24 weeks cured three quarters of ......MORE |
Simeprevir + sofosbuvir produces high sustained response rates for hard-to-treat patients in COSMOS trialLiz Highleyman | 11 years ago A 12-week all-oral combination of simeprevir plus sofosbuvir led to sustained virological response ......MORE |
BMS interferon-free combination cures over 90% of genotype 1 hepatitis C in 12 weeksKeith Alcorn | 11 years ago A combination of three direct-acting antivirals developed by Bristol-Myers Squibb cured chronic hep......MORE |
Merck interferon-free combination shows high hepatitis C cure rate in early studyKeith Alcorn | 11 years ago A two-drug combination of direct-acting antivirals developed by Merck achieved very high cure rates......MORE |
Need for expansion of hepatitis C screening among veterans, 'baby-boom' generation and pregnant women highlightedKeith Alcorn | 11 years ago Two large studies of the 'baby-boom' generation in the United States suggest that at least 50,000 U......MORE |
AbbVie’s two-drug, interferon-free combination cures genotype 1b hepatitis C infection in 95%Keith Alcorn | 11 years ago A two-drug combination of direct-acting antivirals developed by AbbVie achieved sustained virologic......MORE |
High response rates with telaprevir triple therapy for HIV-positive men with acute hepatitis CLiz Highleyman | 11 years ago Adding telaprevir (Incivo or Incivek) to pegylated interferon and ribavirin shortens the duration o......MORE |
In ELECTRON trial, 100% of hard-to-treat patients cured with sofosbuvir/ledipasvir plus ribavirin or GS-9669Liz Highleyman | 11 years ago Interferon-free regimens of sofosbuvir and ledipasvir plus either ribavirin or GS-9669 taken for 12......MORE |
Urgent need to improve sexually transmitted infection screening for MSM in EuropeRoger Pebody | 11 years ago Across 40 large European cities, less than one third of men who have sex with men (MSM) have been s......MORE |
Gay men who don't have anal sex still at high risk of bacterial STIsMichael Carter | 11 years ago Gay men may still have a significant risk of syphilis and urethral gonorrhoea even if they do not h......MORE |
Once-daily raltegravir effective as maintenance therapyLiz Highleyman | 11 years ago Almost all HIV-positive people with undetectable viral load who switched to once-daily raltegravir ......MORE |
HIV rebound linked to higher baseline level, slower suppression and low-level viraemiaLiz Highleyman | 11 years ago Higher baseline viral load, longer time to viral suppression and low-level viraemia below the level......MORE |
Simultaneous HIV and tuberculosis therapy doesn't cause problems with liver functionMichael Carter | 11 years ago Simultaneous treatment with anti-tuberculosis (TB) drugs and antiretroviral therapy (ART) does not ......MORE |
Dolutegravir matches or surpasses other regimens for first-line HIV treatmentLiz Highleyman | 11 years ago The recently approved HIV integrase inhibitor dolutegravir (Tivicay) provides at least equivalent a......MORE |
HCV reinfection is common among HIV-positive gay men in EuropeLiz Highleyman | 11 years ago Nearly 10% of HIV-positive men acquired hepatitis C virus (HCV) a second time after clearing the vi......MORE |
High prevalence of osteoporosis and osteopenia in young men with HIVMichael Carter | 11 years ago There is an increased prevalence of osteoporosis and osteopenia in young HIV-positive men, Spanish ......MORE |
Low CD4 cell count increases heart attack risk for people with HIVMichael Carter | 11 years ago Immunodeficiency is an important risk factor for heart attack in people living with HIV, results of......MORE |
Social problems and drug and alcohol problems common among people who develop AIDS despite long-term HIV careMichael Carter | 11 years ago Psychiatric, drug, alcohol and social care problems are highly prevalent among people who develop s......MORE |
Social problems and drug and alcohol abuse common among people who develop AIDS despite long-term HIV careMichael Carter | 11 years ago Psychiatric, drug, alcohol and social care problems are highly prevalent among people who develop s......MORE |
Pre-test counselling does not reduce sexual risk reduction – findings support streamlined HIV testing proceduresRoger Pebody | 11 years ago A large randomised controlled trial of rapid HIV testing, with or without risk-reduction counsellin......MORE |
Pre-test counselling does not reduce sexual risk taking – findings support streamlined HIV testing proceduresRoger Pebody | 11 years ago A large randomised controlled trial of rapid HIV testing, with or without risk-reduction counsellin......MORE |
Late testing rates declining in Europe, but largely in gay menGus Cairns | 11 years ago Over Europe as a whole, the proportion of people testing late for HIV decreased between 2002 and 20......MORE |
Considerable increase in unprotected sex found in French/Canadian gay surveyGus Cairns | 11 years ago A French and Canadian online survey of gay men and other men who have sex with men (MSM) appears to......MORE |
Tel Aviv and Bucharest signal warnings of new HIV epidemics among people who inject drugsKeith Alcorn | 11 years ago A switch to a cheaper injectable illicit drug led to a major outbreak of HIV infection in Tel Aviv,......MORE |
Future HIV care will include both novel antiretroviral drugs and new treatment strategiesLiz Highleyman | 11 years ago HIV treatment in the coming years will include novel antiretroviral agents and new formulations suc......MORE |
Faldaprevir demonstrates good early response in genotype 1 HIV/HCV co-infectionLiz Highleyman | 11 years ago The HCV protease inhibitor faldaprevir added to pegylated interferon and ribavirin increased the li......MORE |
Suicide rates tumble in people with HIV in Canadian study but psychiatric drug use remains high in Danish people with HIVGus Cairns | 11 years ago A study presented at the 14th European AIDS Conference last week found that the suicide rate in peo......MORE |
Simeprevir with interferon effective for HIV/HCV co-infected people with genotype 1 hepatitis CLiz Highleyman | 11 years ago Adding the direct-acting hepatitis C drug simeprevir to pegylated interferon and ribavirin produced......MORE |
Dual therapy with Kaletra and 3TC works well regardless of viral loadLiz Highleyman | 11 years ago A dual combination of lopinavir/ritonavir (Kaletra or Aluvia) plus 3TC (lamivudine, Epivir) as firs......MORE |
GSK1265744 rapidly suppresses HIV and appears safe at selected doseLiz Highleyman | 11 years ago The experimental HIV integrase inhibitor GSK1265744 demonstrated rapid and potent antiviral activi......MORE |
Ensuring good-quality HIV care in Europe: where can we improve?Keith Alcorn | 11 years ago Only 20% of people with HIV in Europe have fully suppressed viral load, compared to an estimated 24......MORE |
New EACS treatment guidelines strike balance between individual choice and public health, say writersGus Cairns | 11 years ago A new edition of the European AIDS Clinical Society (EACS) guidelines for the treatment of HIV, HIV......MORE |
New drugs will bring revolution in hepatitis C treatmentLiz Highleyman | 11 years ago The advent of direct-acting antiviral agents can rightly be described as a revolution in treatment ......MORE |
CCR5 inhibitor cenicriviroc shows good activity against HIV; new formulation may reduce dropoutsLiz Highleyman | 11 years ago The dual CCR5/CCR2 inhibitor cenicriviroc demonstrated good antiviral activity and tolerability in ......MORE |
Number of people infected with drug-resistant HIV in Europe has risen by around 35%Keith Alcorn | 11 years ago The number of people in Europe who have become infected with a drug-resistant strain of HIV may hav......MORE |
Anal cancer screening may be appropriate for all women with HIV, French researchers suggestKeith Alcorn | 11 years ago Women living with HIV had a higher risk of anal pre-cancerous changes than cervical changes linked ......MORE |
Experts debate whether HIV cure is 'hype or hope'Liz Highleyman | 11 years ago Is a functional cure for HIV feasible within the foreseeable future or is it a hopeless quest robbi......MORE |
Researchers and advocates discuss biomedical HIV preventionLiz Highleyman | 11 years ago The first day of the 14th European AIDS Conference, which opened yesterday in Brussels, featured a ......MORE |
Researchers and advocates discuss the microbicides pipeline in EuropeLiz Highleyman | 11 years ago The first day of the 14th European AIDS Conference, which opened yesterday in Brussels, featured a ......MORE |
Eastern Europe facing quadruple epidemic while governments do nothing, warns UN Special EnvoyKeith Alcorn | 11 years ago Eastern Europe is facing quadruple, intersecting epidemics of injecting drug use, HIV, tuberculosis......MORE |
Vaccine trials – where next?Gus Cairns | 11 years ago New efficacy trials of HIV vaccines based on what has been learned in the RV144 vaccine trial in Th......MORE |
European physicians condemn impact of Russian anti-gay law on HIV prevention and careKeith Alcorn | 11 years ago The European AIDS Clinical Society (EACS) has strongly condemned the discriminatory legal and polic......MORE |
Big differences in virological outcomes among people taking first-line HIV therapy in resource-limited settingsMichael Carter | 11 years ago Virological outcomes vary enormously among people taking antiretroviral therapy in different resour......MORE |
HIV-positive people not on antiretrovirals are prone to inflammation-related bone lossLiz Highleyman | 11 years ago HIV-positive people not taking antiretroviral therapy experienced more bone mineral density loss at......MORE |
HIV-positive young women have adequate response to human papillomavirus vaccineLiz Highleyman | 11 years ago HIV-positive girls did not respond as well to the quadrivalent human papillomavirus (HPV) vaccine a......MORE |
Only a fifth of pregnancies among women living with HIV in the US are plannedMichael Carter | 11 years ago Only a fifth of pregnancies among women living with HIV in the United States are planned, research ......MORE |
Predicting response to acute hepatitis C treatment in HIV/HCV co-infected peopleLiz Highleyman | 11 years ago HIV/HCV co-infected people with higher HCV viral load, lower CD4 cell counts, older age and unfavou......MORE |
Young people (15 to 24 years) especially likely to drop out of HIV careMichael Carter | 11 years ago Patients aged between 15 and 24 years are significantly more likely to drop out of HIV compared to ......MORE |
Eviplera works well regardless of viral load or CD4 count, may improve lipid levelsLiz Highleyman | 11 years ago The single-tablet regimen Eviplera (rilpivirine/tenofovir/emtricitabine) worked as well as Atripla ......MORE |
Unravelling the mystery of the vaccine trialsGus Cairns | 11 years ago There have been thousands of small vaccine trials in the history of HIV – the first one took plac......MORE |
HIV monitoring every six months is adequate for people on ART with stable viral suppressionLiz Highleyman | 11 years ago People with HIV who have their viral load and CD4 cell count monitored every six months were no mor......MORE |
Specialised testing and social marketing campaigns increase the detection of acute HIV infection among gay menMichael Carter | 11 years ago Big increases in diagnosis rates of acute HIV infection (AHI) can be achieved with the use of targe......MORE |
Daclatasvir works well against hepatitis C either with interferon or in all-oral regimenLiz Highleyman | 11 years ago A short 12- or 16-week triple regimen of daclatasvir plus pegylated interferon/ribavirin cured more......MORE |
Researchers see further positive results with herpes virus-based vaccines in monkeysGus Cairns | 11 years ago One of the biggest news stories at the AIDS Vaccine 2013 conference was the groundbreaking experime......MORE |
Female condom choices are expanding – new models have low failure rates and are acceptable to usersRoger Pebody | 11 years ago A randomised trial has shown that three new models of female condom are non-inferior to the establi......MORE |
The monkeys’ tale – how a vaccine might nip HIV in the budGus Cairns | 11 years ago Four dozen rhesus monkeys may have successfully fought off the monkey equivalent of HIV in a series......MORE |
UK patients with MDR-TB have good outcomes but a quarter not receiving the recommended duration of therapyMichael Carter | 11 years ago Approximately 25% of people with multidrug-resistant tuberculosis (MDR-TB) in the UK are not comple......MORE |
People with HIV have higher risk of death after heart attackLiz Highleyman | 11 years ago People with HIV had higher mortality than HIV-negative individuals after hospitalisation for acute ......MORE |
Does efavirenz use raise the risk of suicide in people with HIV?Liz Highleyman | 11 years ago Suicidal thoughts, attempted suicide and death by suicide were more than twice as common amongst pe......MORE |
HIV vaccine conference opens in most promising research atmosphere for yearsGus Cairns | 11 years ago The 13th – and last – AIDS Vaccine 2013 Conference opened today in Barcelona in an atmosphere o......MORE |
Studies look at community vs hospital-based HIV care and medication issuesLiz Highleyman | 11 years ago HIV-positive people treated at community clinics were more likely to continue receiving care, while......MORE |
Revisiting the safety spectrum: how gay men fall into different 'risk classes' for HIVGus Cairns | 11 years ago Gay men fall into different groups that are at radically different risk for acquiring HIV, Canadian......MORE |
Liver fibrosis linked to immune activation in HIV/HCV co-infected womenLiz Highleyman | 11 years ago CD4 and CD8 cell activation were found to be associated with biomarkers of liver fibrosis among HIV......MORE |
Many HIV-positive people not receiving recommended prevention counselling as part of their routine careMichael Carter | 11 years ago Approximately half of HIV-positive people in the United States are not receiving prevention counsel......MORE |
Long-acting antiretrovirals may improve survival for people with poor adherenceLiz Highleyman | 11 years ago Long-acting antiretroviral formulations taken once-monthly or less have the potential to improve su......MORE |
Liver cancer often diagnosed late with poor survival in people with HIVLiz Highleyman | 11 years ago Hepatocellular carcinoma is frequently diagnosed at an advanced stage in HIV-positive people with h......MORE |
New integrase inhibitor GSK1265744 safe and well tolerated in eight studiesLiz Highleyman | 11 years ago The investigational HIV integrase inhibitor GSK1265744 was well tolerated, with no notable safety c......MORE |
Home-based counselling and testing achieves very high testing rates in KenyaCarole Leach-Lemens | 11 years ago A home-based counselling and testing (HBCT) programme in western Kenya achieved 96% uptake of HIV t......MORE |
Is HCV infection spreading among HIV-positive gay men in Japan?Liz Highleyman | 11 years ago The incidence of acute hepatitis C virus (HCV) co-infection has increased in recent years at the la......MORE |
People's friends diagnose brain impairment better than they do themselvesGus Cairns | 11 years ago Baseline results from a longitudinal study of 235 gay men with HIV aged 18 to 50 attending the Mort......MORE |
Microbicide ring study shows users are reassured about discomfort but develop new worries about safetyGus Cairns | 11 years ago A safety and acceptability study of a vaginal ring containing the antiretroviral drugs dapivirine (......MORE |
Men attending group sex 'slam parties' don’t all use or inject drugsGus Cairns | 11 years ago There has been considerable publicity in the gay, scientific and general media recently about so-ca......MORE |
Cross-sectional study suggests circumcision is having a big impact on HIV rates among men in Orange Farm, South AfricaMichael Carter | 11 years ago Research conducted in South Africa suggests that the roll-out of circumcision is reducing the preva......MORE |
Stribild is effective and well tolerated in older people with HIVLiz Highleyman | 11 years ago The Stribild single-tablet regimen matched both Atripla and boosted atazanavir (Reyataz) in efficac......MORE |
Who will PrEP be for?Gus Cairns | 11 years ago Whether pre-exposure prophylaxis (PrEP) is adopted and is effective as an HIV prevention method dep......MORE |
Infection with HIV associated with increased risk of dialysis and end-stage kidney diseaseMichael Carter | 11 years ago HIV infection increases the risk of kidney disease requiring renal replacement therapy or dialysis,......MORE |
Political leadership on finance and pace of scale-up needed to realise full potential of treatment as preventionKeith Alcorn | 11 years ago Achieving the full potential of antiretroviral treatment as a prevention method will require govern......MORE |
Tenofovir vaginal ring protects monkeys on Depo-Provera against HIV-like virusLiz Highleyman | 11 years ago An intravaginal ring containing tenofovir protected all but one macaque monkey given hormonal contr......MORE |
Uptake of PrEP may be limited because few gay men think they are at risk of HIV infectionRoger Pebody | 11 years ago Three quarters of gay men seeking HIV testing at a Toronto sexual health clinic were assessed as be......MORE |
Treating HCV genotypes 2 and 3 in HIV/HCV co-infected peopleLiz Highleyman | 11 years ago People co-infected with HIV and HCV, mostly with hepatitis C virus (HCV) genotype 3, responded abo......MORE |
Making treatment as prevention a reality for people who inject drugsKeith Alcorn | 11 years ago People who inject drugs risk being left behind as countries make efforts to scale up antiretroviral......MORE |
Single-tablet regimen improves antiretroviral adherence and reduces hospitalisationLiz Highleyman | 11 years ago Antiretroviral treatment that requires only a single tablet taken once daily were associated with b......MORE |
HPV type 39 linked to anal dysplasia, better screening needed for HIV+ men and womenLiz Highleyman | 11 years ago About two-thirds of gay men and one-fifth of women tested in Spain were found to have cell or tissu......MORE |
Economic austerity affects the way in which HIV-positive Londoners view ‘treatment as prevention’Roger Pebody | 11 years ago Discussions of an economic crisis and of austerity contribute to the manner in which people living ......MORE |
Switching from Atripla to Eviplera reduces central nervous system side-effectsLiz Highleyman | 11 years ago People who switched single-tablet regimens from Atripla (efavirenz/tenofovir/emtricitabine) to Evip......MORE |
Late HIV diagnosis continues to be a Europe-wide problemMichael Carter | 11 years ago Late diagnosis of HIV remains a serious problem across Europe, results of a large study published i......MORE |
Interferon response reduces liver disease and death in HIV/HCV co-infected peopleLiz Highleyman | 11 years ago Effective interferon-based therapy that produces sustained virological response led to significant ......MORE |
"If I am given antiretrovirals I will think I am nearing the grave" – a challenge for early treatment strategiesRoger Pebody | 11 years ago Kenyan people living with HIV perceive antiretroviral therapy to be something that is taken in the ......MORE |
Raltegravir appears safe for mothers and babies during pregnancyLiz Highleyman | 11 years ago Antiretroviral regimens containing the integrase inhibitor raltegravir (Isentress) were shown to be......MORE |
Depression linked to episodes of detectable HIV in cerebrospinal fluidLiz Highleyman | 11 years ago People who experience episodes of major depressive disorder (MDD) are significantly more likely to ......MORE |
South American survey finds rectal microbicide formulated as a douche acceptableGus Cairns | 11 years ago A qualitative study of 140 men who have sex with men (MSM) and transgender women (TGW) is three cit......MORE |
Gay men recall seeing mass media campaign, but impact on behaviour remains unclearRoger Pebody | 11 years ago A media campaign promoting condom use and sexual health check-ups to gay and other men who have sex......MORE |
Novel NNRTI AIC292 works well against drug-resistant HIVLiz Highleyman | 11 years ago The next-generation HIV non-nucleoside reverse transcriptase inhibitor (NNRTI) AIC292 showed good a......MORE |
New NNRTI MK-1439 interacts with ritonavir but not tenofovirLiz Highleyman | 11 years ago Blood levels of MK-1439, a next-generation HIV non-nucleoside reverse transcriptase inhibitor (NNRT......MORE |
Dolutegravir shows good efficacy across broad range of patient groupsLiz Highleyman | 11 years ago The new integrase inhibitor dolutegravir worked better than boosted darunavir for people starting H......MORE |
US PrEP prescriptions more likely to go to Southern womenGus Cairns | 11 years ago A US survey of the prescribing of Truvada (tenofovir/emtricitabine) to HIV-negative people as pre-e......MORE |
New tenofovir formulation works equally well with less effect on kidneys and bonesLiz Highleyman | 11 years ago Tenofovir alafenamide (TAF), a new formulation that produces higher drug levels in cells but allows......MORE |
Raltegravir is a good choice for people with HIV undergoing cancer chemotherapyLiz Highleyman | 11 years ago The integrase inhibitor raltegravir (Isentress) may be an optimal choice for many HIV-positive peop......MORE |
CD4 gene therapy may enable functional HIV control during treatment interruptionLiz Highleyman | 11 years ago Two people whose CD4 T-cells were modified to make them resistant to HIV entry experienced substant......MORE |
Hepatitis E virus infection associated with HIV and damage to gut mucosa, Zambian study showsMichael Carter | 11 years ago The prevalence of hepatitis E virus (HEV) infection is strongly associated with HIV status, results......MORE |
Systematic review confirms that regular viral load monitoring assists adherence to HIV therapyMichael Carter | 11 years ago Routine viral load monitoring means that people with treatment adherence problems can be identified......MORE |
Sexual role versatility among HIV-negative US MSM contributing to high level of HIV incidenceMichael Carter | 11 years ago Versatility in anal sex roles is a likely explanation for the continued high rate of new HIV transm......MORE |
Integration of HIV care into primary care reduces deaths in South African trialCarole Leach-Lemens | 11 years ago Integrating HIV care into primary care can improve survival of HIV-positive patients in need of ART......MORE |
Loss of kidney function in older people with HIV underlines need for earlier treatmentMichael Carter | 11 years ago Kidney function deteriorates more rapidly in older people with HIV than in age-matched controls in ......MORE |
Intravenous AZT does not provide extra protection against vertical transmission in mothers with undetectable viral loadCarole Leach-Lemens | 11 years ago Intravenous (IV)-zidovudine (AZT or ZDV) during labour and delivery is effective in reducing mother......MORE |
Text messages do not reduce early resumption of sexual activity in recently circumcised menCarole Leach-Lemens | 11 years ago Text messaging did not help reduce early resumption of sex after male circumcision (MC) in a large ......MORE |
Tenofovir is highly effective for HIV/HBV co-infection, meta-analysis showsLiz Highleyman | 11 years ago Home aidsmap.com Full site Tenofovir is highly effective ......MORE |
Decompensated cirrhosis increases risk of liver cancer for people with HIV and viral hepatitis co-infectionMichael Carter | 11 years ago There is a relatively low incidence of hepatocellular carcinoma (HCC) among people living with HIV ......MORE |
People with HIV/HCV-co-infection and advanced liver fibrosis can rapidly develop decompensated liver diseaseMichael Carter | 11 years ago People living with HIV who have hepatitis C virus (HCV) co-infection and advanced liver fibrosis ca......MORE |
Global AIDS mortality fell by over 20% in last five years, but large inequalities remain between countriesGus Cairns | 11 years ago The overall annual death rate from AIDS has fallen by 21% since 2006, the most recent study in the ......MORE |
Persisently detectable viral load at any level increases risk of HIV treatment failureMichael Carter | 11 years ago For people taking HIV therapy, a persistent detectable viral load at any level is associated with a......MORE |
High rates of anal HPV infection among young gay menMichael Carter | 11 years ago Prevalence and incidence of anal human papillomavirus (HPV) are high among young gay men, according......MORE |
Partner violence may undermine use of female-controlled forms of HIV preventionMichael Carter | 11 years ago Women who experience violence from their male partner are less likely to use condoms or diaphragms,......MORE |
A fifth of gay men in a relationship with an HIV-negative man have not tested for HIV while in their current relationshipMichael Carter | 11 years ago A fifth of gay men in a relationship with an HIV-negative male partner have not had an HIV test whi......MORE |
Kenyan sex workers and men who have sex with men find PrEP acceptable but worry about others' assumptionsGus Cairns | 11 years ago Qualitative interviews from an already published placebo-controlled study of 66 men who have sex wi......MORE |
High proportion of Canadian patients with HIV-HCV co-infection and liver cirrhosis are not having ultrasounds to check for liver cancerMichael Carter | 11 years ago Over a third of HIV-positive people with hepatitis C virus-related liver cirrhosis are not having r......MORE |
Low baseline CD4 cell count associated with greater bone loss after starting HIV therapyMichael Carter | 11 years ago A low baseline CD4 cell count is associated with loss of bone mineral density (BMD) during the earl......MORE |
Cleared HCV infection associated with increased risk of kidney disease in people with HIVMichael Carter | 11 years ago People living with HIV with previous hepatitis C virus (HCV) infection continue to have an increase......MORE |
High prevalence of CMV retinitis among HIV-positive patients in Asia and AfricaMichael Carter | 11 years ago Prevalence of CMV retinitis remains high among HIV-positive patients in resource-limited settings, ......MORE |
Considerable increase in unprotected sex found in French gay surveyGus Cairns | 11 years ago A French and Canadian online survey of gay men and other men who have sex with men (MSM) appears to......MORE |
Legal barrier to self-testing for HIV in UK to be liftedKeith Alcorn | 11 years ago The Department of Health announced an important change to HIV testing policy for the United Kingdom......MORE |
UK health care workers with HIV to be cleared for dental and surgical workKeith Alcorn | 11 years ago Health care workers in the United Kingdom living with HIV will be permitted to carry out exposure-p......MORE |
UK healthcare workers with HIV to be cleared for dental and surgical workKeith Alcorn | 11 years ago Healthcare workers in the United Kingdom living with HIV will be permitted to carry out exposure-pr......MORE |
Pegylated interferon with antiretroviral therapy achieves promising results in patients with difficult-to-treat Kaposi's sarcomaMichael Carter | 11 years ago Pegylated interferon alfa-2a (PegIFN) may be an effective therapy for Kaposi's sarcoma (KS) that ha......MORE |
High prevalence of heart rhythm disturbance among HIV-positive people on methadone maintenance therapyMichael Carter | 11 years ago Spanish investigators have identified a high prevalence of a potentially life-threatening disturban......MORE |
CD4 cell count at time of entry to HIV care did not increase significantly between 1992 and 2011Michael Carter | 11 years ago The average CD4 cell count of people newly entering HIV care in resource-rich countries did not inc......MORE |
Few AIDS diagnoses among people with higher CD4 cell counts, but risk remains elevated for those with a count below 750Michael Carter | 11 years ago Incidence of AIDS-defining illnesses remains elevated even when the CD4 cell count is between 500 a......MORE |
Immune suppression and smoking history are risks for HPV-related anal disease in HIV-positive gay menMichael Carter | 11 years ago Risk factors for human papillomavirus (HPV)-associated anal disease in HIV-positive gay men are sim......MORE |
Community study finds no evidence of widespread HCV epidemic among HIV-negative gay men in LondonMichael Carter | 11 years ago Approximately 1% of HIV-negative gay men in London had antibodies to the hepatitis C virus (HCV) in......MORE |
A quarter of HIV/HCV-co-infected people in EuroSIDA have received HCV therapyMichael Carter | 11 years ago A quarter of HIV-positive people in the EuroSIDA cohort with chronic hepatitis C virus (HCV) co-inf......MORE |
Evidence is not yet sufficient to recommend universal treatment, clinicians and community writers sayGus Cairns | 11 years ago We do not yet have sufficiently strong evidence to recommend that antiretroviral treatment (ART) sh......MORE |
HIV treatment has not led to increasing sexual risk-taking in rural South African communitiesGus Cairns | 11 years ago A study from a rural area in the province of KwaZulu Natal, South Africa, has found no evidence tha......MORE |
Opportunities being missed for a vaginal delivery for HIV-positive pregnant women in Europe with viral suppressionMichael Carter | 11 years ago There are “missed opportunities” for HIV-positive pregnant women with a suppressed viral load t......MORE |
Smoking cannabis does not accelerate progression of liver disease in people with HIV/HCV co-infectionMichael Carter | 11 years ago Smoking cannabis does not worsen liver disease in people with HIV and hepatitis C virus (HCV) co-in......MORE |
Drinking alcohol doesn't increase the risk of HIV treatment failureMichael Carter | 11 years ago Alcohol consumption has little impact on key markers used to monitor the health of individuals with......MORE |
Investigators identify genetic profile associated with better treatment outcomes in people with HIV/HCV co-infectionMichael Carter | 11 years ago Several genetic characteristics are associated with a successful response to treatment for hepatiti......MORE |
Lymphoma mortality rates remain elevated among HIV-positive people in the United StatesMichael Carter | 11 years ago HIV-positive people in the United States diagnosed with certain types of lymphoma continue to have ......MORE |
Biomedical HIV prevention – the social complexities of achieving effectivenessRoger Pebody | 11 years ago Public health officials, donors, epidemiologists, researchers and clinicians need to factor in the ......MORE |
Only a weak association between immune suppression and increased cardiovascular disease risk for people with HIVMichael Carter | 11 years ago There is only a weak association between immune suppression and risk of heart attack and coronary h......MORE |
Number of patients diagnosed with HCV in England increased by a third between 2010 and 2012Michael Carter | 11 years ago The UK is making progress in the prevention, diagnosis and treatment of hepatitis C virus (HCV), a ......MORE |
"Strong" argument for providing HPV vaccination to younger gay men in the UKMichael Carter | 11 years ago There is a “strong” argument for extending UK HPV (human papillomavirus) vaccination programmes......MORE |
Gay men diagnosed with a rectal STI have a very high risk of subsequent infection with HIVMichael Carter | 11 years ago The rate of new HIV infections is especially high among gay men recently diagnosed with a rectal se......MORE |
HIV/HCV co-infected people can do well on hepatitis C triple therapy despite contraindicationsLiz Highleyman | 11 years ago Nearly three-quarters of HIV/HCV co-infected patients in the French HEPAVIH cohort achieved end-of-......MORE |
What HIV self-testing may mean for couplesLaura Lopez Gonzalez | 11 years ago A study in Malawi is offering glimpses into why couples opt for HIV self-testing – including issu......MORE |
Women with HIV feel 'under surveillance' during pregnancy and early motherhoodRoger Pebody | 11 years ago Women living with HIV are subject to questioning, monitoring and surveillance of their choices duri......MORE |
Many gay men enjoy bareback porn, but are concerned about its possible effects on sexual behaviourRoger Pebody | 11 years ago Many gay men who watch pornography enjoy and sometimes prefer material in which condoms are not use......MORE |
Medical male circumcision campaigns face cultural challenges in southern AfricaLaura Lopez Gonzalez | 11 years ago Campaigns to circumcise tens of thousands of men in southern Africa are falling victim to lingering......MORE |
Genetic testing lowers risk of nevirapine skin rashLiz Highleyman | 11 years ago Screening for genetic mutations could substantially reduce the risk of hypersensitivity reactions i......MORE |
Vaccination could prevent infection with anal cancer-associated HPV strains in older gay menMichael Carter | 11 years ago A large number of infections with anal cancer-associated strains of human papillomavirus (HPV) amon......MORE |
Male circumcision: the message is catching on, but scale-up poses monitoring and follow-up problemsGus Cairns | 11 years ago Programmes offering voluntary medical male circumcision (VMMC) as part of HIV prevention are now st......MORE |
Six in ten European gay men have had unprotected sex in the past year – more common with steady partnersRoger Pebody | 11 years ago Across Europe, 58% of gay and other men who have sex with men (MSM) report at least one incident of......MORE |
South African couples living with HIV are missing out on safer conception adviceLaura Lopez Gonzalez | 11 years ago Clinicians and counsellors may understand the right of people living with HIV to have children, but......MORE |
Text messages to mothers improve early infant HIV diagnosis rates in Kenya and MozambiqueCarole Leach-Lemens | 11 years ago Use of text messaging significantly improved the rate of early infant diagnosis (EID) among HIV-pos......MORE |
'Option B+' women are at increased risk of loss to follow-up after starting HIV treatmentLesley Odendal | 11 years ago Women who begin HIV treatment during pregnancy, or while breastfeeding, prior to the CD4 cell thres......MORE |
Kidney problems linked to tenofovir use, improve with switch to abacavirLiz Highleyman | 11 years ago Indian people with HIV taking tenofovir had a higher rate of kidney impairment than westerners, acc......MORE |
Stigma, delay and misunderstanding slow access to ART in AfricaGus Cairns | 11 years ago Three presentations at the recent 7th International AIDS Society conference on HIV Pathogenesis, T......MORE |
Scientists and clinicians must challenge HIV-related stigma and ensure enabling legal and policy environments, IAS conference hearsEdwin J. Bernard | 11 years ago Scientists should not only create knowledge to improve the HIV epidemic, they also have a duty to s......MORE |
Efavirenz in children: WHO dosing guidelines raise the risk of side-effects in Thai childrenCarole Leach-Lemens | 11 years ago Taking efavirenz according to 2010 World Health Organization (WHO) guidelines ensures a higher prop......MORE |
Non-African middle-income countries pay four times more for ARVs than African middle-income countriesLesley Odendal | 11 years ago Middle-income countries outside Africa are paying, on average, four times more for antiretrovirals ......MORE |
Darunavir/ritonavir safe and effective for younger childrenCarole Leach-Lemens | 11 years ago Over 80% of treatment-experienced children with HIV aged three to six years from ten sites in Argen......MORE |
Lower-dose lopinavir/ritonavir reduces side-effects, maintains viral control in Thai childrenCarole Leach-Lemens | 11 years ago Low dose lopinavir/ritonavir (LPV/r) – 70% of the standard dose – worked as well as standard do......MORE |
Magical thinking? FEM-PrEP trial may have failed because participants used testing as preventionGus Cairns | 11 years ago While the 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (......MORE |
Malaysia’s harm reduction programmes are preventing infections and saving money, but reaching far too few people who inject drugsRoger Pebody | 11 years ago An expansion of methadone maintenance and needle exchange programmes in Malaysia, a conservative Mu......MORE |
Fibroscan accurately predicts liver decompensation and death in HIV/HCV co-infected peopleLiz Highleyman | 11 years ago The non-invasive transient elastometry method of estimating liver damage may be a better way to pre......MORE |
Studies look at bone changes during second-line therapy, fractures, and HIV- and HCV-related bone lossLiz Highleyman | 11 years ago People with HIV experience less bone loss if they switch to a NRTI-sparing second-line regimen cont......MORE |
Strategies to detect and treat MSM with acute infection may be a powerful tool to control HIV epidemicsRoger Pebody | 11 years ago The detection and control of acute (very recent) HIV infection may be a powerful HIV prevention mea......MORE |
Long-acting GSK1265744 and TMC278-LA appear safe and practical in early studyLiz Highleyman | 11 years ago A combination of antiretroviral drugs in long-acting nanosuspension formulations achieved adequate ......MORE |
No increase in risk behaviour in people taking antiretroviral therapy, meta-analysis showsRoger Pebody | 11 years ago One of the anxieties in relation to ‘treatment as prevention’ is that it may discourage people ......MORE |
First-line antiretroviral therapy has improved over time, meta-analysis showsLiz Highleyman | 11 years ago The effectiveness of initial antiretroviral treatment has improved markedly over the years, but man......MORE |
Intervention with cash lottery prizes cuts HIV infection by 39% in young women in LesothoRoger Pebody | 11 years ago An HIV prevention intervention in which young people who had tested negative for sexually transmitt......MORE |
Ambitious plans for treatment as prevention in Asia, but challenges remainRoger Pebody | 11 years ago Countries such as China, Cambodia and Vietnam have made strong commitments to curbing their HIV epi......MORE |
Dolutegravir superior to raltegravir for treatment-experienced people with HIVLiz Highleyman | 11 years ago The once-daily HIV integrase inhibitor dolutegravir demonstrated better efficacy than twice-daily r......MORE |
Reduced efavirenz dose suppresses HIV as well as standard doseLiz Highleyman | 11 years ago Lowering the dosage of efavirenz (Sustiva or Stocrin) from 600 to 400mg in an antiretroviral regime......MORE |
Study supports WHO recommendations for second-line HIV therapy in resource-limited countriesLiz Highleyman | 11 years ago A second-line regimen consisting of a protease inhibitor (PI) plus two nucleoside/nucleotide revers......MORE |
Bangkok PrEP study finds PrEP efficacy is related to drug exposureGus Cairns | 11 years ago The 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention heard ......MORE |
PrEP appears safe for use in conception, but may not be necessary if partner is taking treatmentRoger Pebody | 11 years ago HIV-negative women who wish to become pregnant with their male HIV-positive partner can be reassure......MORE |
First-ever community-randomised combination prevention trial produces modest drop in HIV incidence, big increase in testing in menGus Cairns | 11 years ago The results of a pioneering HIV prevention trial comparing the effects of mobile HIV testing, commu......MORE |
Two stem cell transplant recipients now controlling HIV off treatmentKeith Alcorn | 11 years ago Two people with HIV who received stem cell transplants for the treatment of lymphoma are now contro......MORE |
How can most-at-risk populations be encouraged to seek HIV testing?Lesley Odendal | 11 years ago Peer-mediated HIV counselling resulted in the highest uptake of HIV counselling and testing (HCT) a......MORE |
Kick, |