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PrEP preferences in gay men are predicted by the frequency and predictability of the sex they have
Gus Cairns, 2015-10-02 08:30:00

A recently-published survey from the US and Canada reveals that on the whole HIV-negative gay men would rather take pre-exposure prophylaxis (PrEP) intermittently and only before they anticipate sex, in what has been called “event-driven” or “on-demand” PrEP.

The study was conducted in 2011 after the iPrEx study results came out and around the time PrEP received approval from the US Food and Drug Administration, so its results were not influenced by later trial results. It was done in preparation for the ADAPT (HPTN 067) trial of three different PrEP regimens, the first results from which were announced at this year’s IAS conference in Vancouver.

The respondents were asked about event-driven and two other types of PrEP – daily and twice-weekly dosing with an added dose after sex (sometimes called ‘time-driven’ dosing). Although event-driven remained the most popular strategy, the popularity of the other two was affected by how frequently participants had condomless anal sex, and whether it was usually planned or sometimes unplanned.