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Does having HIV affect response to hepatitis C treatment?
Liz Highleyman, 2016-05-16 07:10:00

A study from the US Veterans Health Administration found that HIV-positive people responded as well as those without HIV to direct-acting antiviral (DAA) therapy for hepatitis C, while a Spanish study showed that people with HIV/HCV co-infection were less likely to be cured. These conflicting findings, presented at the recent International Liver Congress in Barcelona, indicate that the interactions between HIV and hepatitis C are still not fully understood.

Approximately one-third of people with HIV are co-infected with hepatitis C virus (HCV). Individuals with co-infection experience more rapid liver disease progression on average, and in the era of interferon-based therapy they did not respond as well to treatment. But some recent studies have suggested that this disparity in treatment response does not apply to interferon-free DAA regimens.