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Condom use in French PrEP trial: half only used PrEP, a quarter used condoms and PrEP, one in six used neither
Gus Cairns, 2016-02-26 20:50:00
An analysis of
condom use in the placebo-controlled phase of the French IPERGAY trial of
intermittent PrEP, presented at the CROI 2016 conference, found that just over
half of the participants had high levels of PrEP use but rarely used condoms, and
about a quarter were “belt-and-braces” users who had high levels of both PrEP
and condom use.
However this left about
one in six trial participants who had low levels of use of both PrEP and
condoms. While their condom use did not change, in a minority of this group
their PrEP use declined significantly during the study.
In this randomised phase of the study, participants did not
know if they were taking PrEP or placebo. A second presentation of results from
the open-label phase of the study, when all participants knew they were on
PrEP, found that the use of condoms where the participant was the receptive partner
declined slightly but significantly, with a relative fall from previous condom
use rates of about 15-20%.