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Low levels of innate immune activation and high levels of gut antibodies may protect people from HIV
Gus Cairns, 2012-08-24 13:40:00
Several research papers published in the last month have reported strong correlations between specific immune responses and protection against HIV infection or its effects. These include a comparison of women in the CAPRISA 004 microbicide trial who became infected and ones who did not, despite high exposure to HIV; an analysis of female sex workers in Kenya who similarly seem to be able to resist HIV infection; and a study of immune responses in a group of monkeys given pre-exposure prophylaxis (PrEP) who all became infected but subsequently developed much lower viral loads.
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