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European guidelines on management of mental health for people with hepatitis C published
Michael Carter, 2012-10-16 07:40:00

European investigators have developed a consensus statement on hepatitis C and mental health. Published in the online edition of the Journal of Hepatology, the wide-ranging document assesses evidence concerning the effect of hepatitis C infection and its treatment on the brain and mental health. It also reviews the evidence for the prevalence and risk factors of psychiatric problems in hepatitis C-infected people and makes recommendations regarding the treatment and care of patients with mental health problems.

An estimated 170 million individuals are infected with hepatitis C worldwide. Chronic infection can lead to permanent liver damage and death. There is a high prevalence of psychiatric problems in people with hepatitis C. Some evidence suggests that the infection itself may be a cause, possibly due to its effect on the central nervous system. It is also well known that standard hepatitis C therapy with pegylated interferon and ribavirin can have psychiatric side-effects. These can include depression, fatigue, insomnia and cognitive disturbances.

Given these concerns, the European Liver Patients Association convened a meeting of European investigators in 2011 to develop a consensus statement based on current knowledge of mental health problems during hepatitis C infection and treatment and the treatment of psychiatric-related disorders.

Their recommendations are based on a grading of the quality of current evidence, and cover six broad areas.

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