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Studies look at brain and cognitive changes in people with HIV as they age
Liz Highleyman, 2017-03-14 07:50:00

People with HIV often show persistent signs of cognitive impairment and abnormalities in brain structure despite suppressive antiretroviral therapy (ART), but they do not appear to experience accelerated decline compared to HIV-negative people as they age, according to research presented at the 2017 Conference on Retroviruses and Opportunistic Infections (CROI) last month in Seattle.

HIV-associated neurocognitive disorder remains a poorly-understood co-morbidity in HIV-positive people. While frank AIDS dementia is now rare among people who receive effective antiretroviral treatment, more subtle cognitive problems – some of which may only be revealed by specialised testing – remain common. Cognitive decline is a concern as the HIV population ages; currently more than half of people living with HIV in the US are over age 50.