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Bacterial vaginosis does not affect efficacy of oral PrEP in women
Gus Cairns, 2017-02-23 14:00:00
Research presented at the Conference on Retroviruses and Opportunistic Infections (CROI 2017) found that the efficacy of oral
PrEP for women was not affected by bacterial vaginosis (BV) – the overgrowth in
the vagina of untypical microbes.
of PrEP in the Partners PrEP study was not significantly different in women
with and without BV. This rules out BV as a possible cause for the lower effectiveness
of oral PrEP in some studies in women, compared to studies in men who have sex
another study did find that tissue concentrations of the drug tenofovir were
lower in women with BV who used a microbicide gel – corroborating a difference
in effectiveness already noticed in the CAPRISA 004 gel study.
now being conducted to find out if BV affected the efficacy of vaginal rings.