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New drug holds out promise of long-term control or even cure of HIV
Gus Cairns, 2015-07-18 17:40:00

Scientists at the Scripps Research Institute in California have discovered a new type of drug that may permanently inhibit HIV from becoming reactivated in the cells that are chronically infected with it. The new drug, didehyro-cortistatin A (dCA), appears to permanently change the cellular environment so that even after it is removed, the cells of the latently-infected reservoir cells remain 100 times less likely to ‘wake up’ and start producing new viruses.

This drug fills a gap in the anti-HIV arsenal that researchers have been in search of for a long time: it is an effective, apparently non-toxic and potent tat inhibitor.

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